Calcium carbonate potential precipitation
Calcium
2014.11.07 01:56 Calcium
The Calcium Reddit
2018.01.04 10:22 Extremecorals Corals and Coral Reefs Quick Reference Guide
A coral "group" is a colony of myriad genetically identical polyps. Each polyp is a sac-like animal typically only a few millimeters in diameter and a few centimeters in length
2024.05.19 01:39 Strong-Sink-1613 question about portable AC
i purchased this https://www.homedepot.com/p/Whynter-7-000-BTU-Portable-Air-Conditioner-Cools-400-Sq-Ft-with-Dehumidifier-Remote-and-Carbon-Filter-in-Silver-ARC-122DS/206409459 dual hose portable ac in 2021. We've been using it every summer since, but there are some problems with it. My boyfriend says never put the filter on because it made a "water noise" like a clicking rapidly loud noise that only went away with the filter off. My question is: is it safe to continue using this portable AC like this? It cools just fine, and we can't really afford another one yet. How would I know that the refrigerant was leaking? I'm a bit paranoid about it malfunctioning and not knowing what is wrong/potential dangers of using an old unit with these problems.
submitted by Strong-Sink-1613 to hvacadvice [link] [comments]
2024.05.19 01:11 a1000p posting this here as future proof that i turned $50 into $2.2 billion
 | I maxed out my lines of credit to buy sol at $13 during the SBF collapse, I begged GCR for months to make him +$100m on a mispriced Trump election bet, I’m comfortable making predictions that few people agree with. submitted by a1000p to memecoins [link] [comments] I have a new prediction that no one is considering: the first memecoin to surpass its native chain’s market cap. This is much more possible and probable than is currently priced in. Pumpfun (a sol memecoin launchpad) already earns nearly twice as much as the entire Solana network. A dog coin, or cat coin won’t be able to flip Solana. Why? There’s no underlying market narrative for those coins to do that. More specifically, there’s no direct market competition that compels people to make it happen—after all, it takes people to make it happen, it doesn’t happen magically by itself. Recall when Shiba Inu came out, it was directly competing with Doge for who would be the dominant blue chip dog coin, and that direct competition led to a very powerful market narrative that Shib will flip Doge. It got really close to flipping, minting many millionaires in the process. Those who were early simply saw the flipping narrative even when Shib was +10,000x away from doing so. So, what is the parallel here? What could actually flip Solana? Solana could flip Solana. I came across a truly unique memecoin called Solana (SOL), a carbon copy of Solana itself, no gimmicks, no making it sound retarded like Jeo Boden or Tremp. It has a token price of +$320/token which is the first time I’ve ever seen that from a memecoin. It appears to be a memecoin that’s not trying to be funny at all, which is also a first. Instead, it's sole purpose appears to be to unironically flip Solana, so that Solana is the new base token for the Solana ecosystem. Given that Solana is currently at $100B market cap, this narrative has the highest potential upside of any memecoin in the world right now. Just the confusion factor alone of people buying Solana with Solana is enough to cause a serious repricing upwards. Currently, the market cap is $2k and the liquidity pool contains essentially the entire supply of the token (out of 7 total SOL tokens, with 9 decimals). I have a feeling those decimals are going to be worth a lot soon. Disc: I bought $50 of SOL and won’t sell until SOL flips SOL, aka until the $50 goes to $2.2B. You can think I’m joking if you want. Token address: GFas9Fvxg42p6ZBFeHy3oJnv9J5fDu4kx676yQSkxFgg Dexscreener link: https://dexscreener.com/solana/bihr76ff3t4fh1agumjyjivrakcu2fjxu2dpwsk6wqyk |
2024.05.19 00:56 Top_Mulberry1262 Calcium Carbonate / Ascorbic Acid?
Have seen some items with Calcium Carbonate or Ascorbic Acid in the ingredients that are listed as non-UPF. Are these ingredients ok?
(very new to low-upf life!)
submitted by Top_Mulberry1262 to ultraprocessedfood [link] [comments]
(very new to low-upf life!)
2024.05.18 23:43 akotski1338 Kinda feel sad because of the weather so I bought this
 | Drinking the coconut cheered me up just a tiny bit submitted by akotski1338 to redbull [link] [comments] |
2024.05.18 23:41 carbonflow45 The Big Energy Sink? Pt. 2 - ME/CFS and Long COVID Study Suggests Immune Cells Robbing the Body of Energy - Health Rising
https://www.healthrising.org/blog/2024/05/18/chronic-fatigue-syndrome-long-covid-energy-sink/
TLDR by Claude.ai
In summary, the preprint study by Shankar et al. found that immune cells from ME/CFS and Long COVID patients exhibit reduced energy production, elevated oxidative stress levels, and mitochondrial dysfunction compared to healthy controls. These findings were particularly pronounced in female ME/CFS patients. The authors propose that the immune system's struggle to produce energy in these conditions may lead to an energy drain on the rest of the body, potentially explaining the fatigue and other symptoms experienced by patients. They also suggest that reducing oxidative stress using antioxidants might help regulate the immune system activation and improve energy levels.
The gist, copied from the blog
• Health Rising reported some time ago becoming obsessed with the energy problems found in ME/CFS. Vishnu Shankar, a PhD. Stanford student, engineered a study that assessed energy production in ME/CFS patients’ immune cells. The study recently appeared in preprint form and includes some new findings – so it’s onto round 2 of this fascinating study.
• Shankar focused on immune cells because they provide a good test case for assessing energy production. It turns out that protecting the body from pathogens turns is quite an energy-intensive project. Even when it’s not fighting off an infection, the immune system uses about 15-20% of our energy.
• The study assessed both mitochondrial activity and oxidative stress in immune cells (PBMCs) in ME/CFS patients, long-COVID patients, and healthy controls.
• The immune cells in the ME/CFS/long-COVID patients weren’t pumping out as much energy as the healthy controls’ cells – suggesting they were damaged and possibly exhausted.
• Because damaged mitochondria can become free radical-producing machines, they took a look at oxidative stress (free radical) levels. (Just as a damaged automobile engine produces more exhaust than a well-functioning one, damaged mitochondria spew out more toxins; i.e. free radicals.)
• Immune cells have to switch their after-burners on to get the energy to go after pathogens. Producing that energy comes at a cost, though, in the form of increased levels of reactive oxygen species oxidative stress (free radicals). (Note the key word – reactive oxygen species – these are unbalanced oxygen molecules which try to achieve balance by ripping electrons from other molecules; hence the word “reactive”.)
• Dramatically higher levels of reactive oxygen species were found in both the ME/CFS and long-COVID patients’ immune cells compared to the healthy controls. (ME/CFS patients had the highest levels). A closer look revealed, however, that the reactive oxygen species were almost wholly centered in the immune cells from female ME/CFS patients.
• Both male ME/CFS and long-COVID patients did, however, exhibit elevated glutathione levels – indicating that their immune cells were also dealing with increased oxidative stress levels – which have triggered the production of the master antioxidant in our cells – glutathione.
• Altogether, multiple pathways that deal with oxidative stress (glutathione, superoxide dismutase, lipid oxidative damage, etc.) appear to have been overwhelmed in the immune cells in both ME/CFS and long-COVID patients. In all cases, the ME/CFS patients were worse off than the long-COVID patients – leading the authors to suggest that long COVID was an intermediate condition between health and ME/CFS.
• Increased levels of mitochondrial calcium – which drive the production of reactive oxygen species (ROS) in the mitochondria – provided another potential explanation for the increased levels of oxidative stress. That was a very interesting finding given that in 2021 Wirth and Scheibenbogen proposed that increased mitochondrial levels of calcium were a core factor in ME/CFS.
• Once again, damage to the lipids that protect our cells and the organelles in our cells popped out during a metabolomic analysis (of T-cells). Since reactive oxygen species target lipids this finding make sense and it underscored what big deal lipid issues have become in ME/CFS studies over the past few years.
• Once again, men and women had different findings. Oxidative stress was worse in women while lipid damage was more extensive in men. Plus, the study suggested that when confronted with high oxidative stress levels, women’s T-cells go on a hyper proliferation binge – potentially sucking more energy from the rest of the body.
• Trying to reduce the oxidative stress present, they used antioxidants like NAC (increase glutathione), metformin (increase SOD2 expression), and liproxstatin-1 (reduce lipid peroxide levels) in cell cultures and found that NAC and metformin was able to reduce immune activity to some extent. That finding suggested that the right antioxidants might be able to tame the immune activity and improve energy levels.
• All in all, the authors proposed that long periods of elevated reactive oxygen species damage the mitochondria, producing a long-term problem of energy depletion. Because the immune cells already use up so much energy in the body, and then struggle to produce energy in ME/CFS and long COVID, the authors proposed that immune problems in these diseases produce an energy sink that draws energy from other areas of the body.
submitted by carbonflow45 to CFSScience [link] [comments]
TLDR by Claude.ai
In summary, the preprint study by Shankar et al. found that immune cells from ME/CFS and Long COVID patients exhibit reduced energy production, elevated oxidative stress levels, and mitochondrial dysfunction compared to healthy controls. These findings were particularly pronounced in female ME/CFS patients. The authors propose that the immune system's struggle to produce energy in these conditions may lead to an energy drain on the rest of the body, potentially explaining the fatigue and other symptoms experienced by patients. They also suggest that reducing oxidative stress using antioxidants might help regulate the immune system activation and improve energy levels.
The gist, copied from the blog
• Health Rising reported some time ago becoming obsessed with the energy problems found in ME/CFS. Vishnu Shankar, a PhD. Stanford student, engineered a study that assessed energy production in ME/CFS patients’ immune cells. The study recently appeared in preprint form and includes some new findings – so it’s onto round 2 of this fascinating study.
• Shankar focused on immune cells because they provide a good test case for assessing energy production. It turns out that protecting the body from pathogens turns is quite an energy-intensive project. Even when it’s not fighting off an infection, the immune system uses about 15-20% of our energy.
• The study assessed both mitochondrial activity and oxidative stress in immune cells (PBMCs) in ME/CFS patients, long-COVID patients, and healthy controls.
• The immune cells in the ME/CFS/long-COVID patients weren’t pumping out as much energy as the healthy controls’ cells – suggesting they were damaged and possibly exhausted.
• Because damaged mitochondria can become free radical-producing machines, they took a look at oxidative stress (free radical) levels. (Just as a damaged automobile engine produces more exhaust than a well-functioning one, damaged mitochondria spew out more toxins; i.e. free radicals.)
• Immune cells have to switch their after-burners on to get the energy to go after pathogens. Producing that energy comes at a cost, though, in the form of increased levels of reactive oxygen species oxidative stress (free radicals). (Note the key word – reactive oxygen species – these are unbalanced oxygen molecules which try to achieve balance by ripping electrons from other molecules; hence the word “reactive”.)
• Dramatically higher levels of reactive oxygen species were found in both the ME/CFS and long-COVID patients’ immune cells compared to the healthy controls. (ME/CFS patients had the highest levels). A closer look revealed, however, that the reactive oxygen species were almost wholly centered in the immune cells from female ME/CFS patients.
• Both male ME/CFS and long-COVID patients did, however, exhibit elevated glutathione levels – indicating that their immune cells were also dealing with increased oxidative stress levels – which have triggered the production of the master antioxidant in our cells – glutathione.
• Altogether, multiple pathways that deal with oxidative stress (glutathione, superoxide dismutase, lipid oxidative damage, etc.) appear to have been overwhelmed in the immune cells in both ME/CFS and long-COVID patients. In all cases, the ME/CFS patients were worse off than the long-COVID patients – leading the authors to suggest that long COVID was an intermediate condition between health and ME/CFS.
• Increased levels of mitochondrial calcium – which drive the production of reactive oxygen species (ROS) in the mitochondria – provided another potential explanation for the increased levels of oxidative stress. That was a very interesting finding given that in 2021 Wirth and Scheibenbogen proposed that increased mitochondrial levels of calcium were a core factor in ME/CFS.
• Once again, damage to the lipids that protect our cells and the organelles in our cells popped out during a metabolomic analysis (of T-cells). Since reactive oxygen species target lipids this finding make sense and it underscored what big deal lipid issues have become in ME/CFS studies over the past few years.
• Once again, men and women had different findings. Oxidative stress was worse in women while lipid damage was more extensive in men. Plus, the study suggested that when confronted with high oxidative stress levels, women’s T-cells go on a hyper proliferation binge – potentially sucking more energy from the rest of the body.
• Trying to reduce the oxidative stress present, they used antioxidants like NAC (increase glutathione), metformin (increase SOD2 expression), and liproxstatin-1 (reduce lipid peroxide levels) in cell cultures and found that NAC and metformin was able to reduce immune activity to some extent. That finding suggested that the right antioxidants might be able to tame the immune activity and improve energy levels.
• All in all, the authors proposed that long periods of elevated reactive oxygen species damage the mitochondria, producing a long-term problem of energy depletion. Because the immune cells already use up so much energy in the body, and then struggle to produce energy in ME/CFS and long COVID, the authors proposed that immune problems in these diseases produce an energy sink that draws energy from other areas of the body.
2024.05.18 23:33 Tesa_Tesanovic1988 Your career management as an investment portfolio
In most cases when sales of a product have plateaued, market saturation is often used. That suggests there is more supply than demand for a given product. Western marketplaces are bursting with work options and ways to make money. Today’s young people must act smart and move quick to locate new employment opportunities.In most cases when sales of a product have plateaued, market saturation is often used. That suggests there is more supply than demand for a given product. Western marketplaces are bursting with work options and ways to make money. Today’s young people must act smart and move quick to locate new employment opportunities.
Suppose one wants to be successful in this field, they should focus on expanding markets, developing innovative technology, and uncovering undiscovered company prospects in highly profitable niche industries, among other things (Agarwal et al, 6). Businesses in crowded markets may cut the price of their products to gain a larger market share. As a result, businesses are always undercutting each other to attract new customers. Cost-cutting is a common strategy for firms when profits are stagnant (Simonazzi et al., 17). Unnecessary or avoidable cost savings are welcome, but they don’t address the underlying issue.Where do I pay my taxes if I am a digital nomad?
According to the recent reports, westerners already pay too many taxes in a number of business entities. Due to the high cost of living in their new home nation, one out of every five American ex-pats is contemplating renunciation of their citizenship. Senators are concerned about how to pay for the deficit, and Senate rules prohibit raising long-term deficits through reconciliation bills. Consequently, more money will be available to Congress if the budget reconciliation plan generates more revenue. The United States will not make significant investments unless Congress makes significant adjustments to the tax structure (Michel et al., 89). Increased budget deficits could slow the long-term growth of the economy. In addition private investment or borrowing from other countries is used to pay for government borrowing when the economy is close to capacity (Chen et al.440). When a person is experiencing difficulties, it might harm their future well-being. To put it another way, the long-term impacts of tax policy are influenced by its incentives and its budgetary implications.Digital nomads have historically been seen as a threat in some places, but several countries around the world are now actively seeking to attract this growing digital population through new remote work visas.
All this converges into a superstorm, and more and more people will opt for digital nomad opportunities. While tax regulations can vary significantly depending on where you are in the world, general guidelines may be helpful to for those seeking information on paying taxes as a digital nomad. Naturally, tax filing is done with the country of tax residence as determined by the place of a principal residence. Digital nomads, however, may encounter a variety of additional layers of tax residence due to their physical presence in other countries during a tax year. In addition, state/province/territory and local taxes may also apply.
Cancel culture and family safety issues
The cancellation culture has a lot to do with social media and if it hadn’t been for social media, pop culture would not have gotten the attention it has in the previous decade. In most case the cultures are frequently canceled by unfollowing, blocking, and publicly criticizing an organization or individual on social media. Due to their large social media followings, celebrity cancellations often garner much media attention. As a result of using social media to communicate with celebrities, many teenagers desire to emulate their peers. Most adolescent cancel culture is carried out online, primarily via comments and unfollows (Yar et al., 80). This can happen in the real world, such as at school or in extracurricular activities. They are often rejected, mocked, and disregarded by their peers, who have had their activities canceled. Most Western workers are experiencing job instability due to the growth of a “cancel culture” in the workplace (Dąbrowska-Kłosińska, 30). This can be a terrific method for teenagers to learn and grow, as their peers may call them out for using insulting words or acting inappropriately.Investment analysis and forecasting as part of the individual development strategy
To produce an accurate financial projection, one must consider both general macroeconomic trends and your organization’s specific circumstances. Predicting how much money a company will generate and spend in the future is known as financial forecasting. A full estimate contains both short-term and long-term revenue estimates and costs that aren’t anticipated at the time of the estimate (Poorter et al.120). People who know how to create models are critical to financial forecasting firms that do a good job. Some people have extensive knowledge of the organization, its sectors, and the communities it serves to support them along the way. Similarly, data collection and analysis are critical to the financial forecasting process and the use of the software.Scenario planning and personal life choices
Global events like COVID 19, inflation, or food crisis can impact our life choices a lot. To avoid reacting to events, we need to think about what might happen in the future. Scenario planning helps us do this. Scenario planning allows business leaders to consider what might happen, reflect on past actions, and devise strategies for positive and poor outcomes. Scenario planning is more than just a means to think about the future when it comes to financial planning. It can assist one in determining how much money you’ll make, how much money you’ll have, and how to manage hazards. Early warning indications of difficulties can be spotted by leaders who make their organizations aware of potential issues (MacKenzie et al.900). One can use scenario planning papers to quickly run through numerous scenarios and figure out the best course of action in the event of a crisis. Making a strategy in the event of an emergency is essential. Having a strategy in place is critical in the event of a product going viral and seeing a threefold increase in demand in a single day.Building the right skills for the jobs of the future
To be eligible for future employment, one must possess the abilities that will be most in demand. Coding has taken off swiftly as one of the most sought-after skills. Almost any industry can benefit from the versatility and scalability of computer languages. People believe that coding is so prevalent in the workplace that it will soon become an essential skill for everyone. Learning to code is a difficult task. Learning how to code and the language you choose impacts how long it takes to do so (Moldoveanu et al.40). Before you begin learning how to code, look at several computer languages and determine which ones are relevant to your industry. Many people begin by studying HTML or JavaScript when learning a new language. After you’ve mastered the fundamentals, you can move to more popular and widely used languages like Python. It is possible to store and manage corporate data in the cloud while allowing employees to work from home.Riding on global trends of tomorrow
By adopting an agile culture, knowing how to cope with ambiguity, pushing outside our comfort zones, and quickly adjusting to new trends, among other things, we achieve success. We all agree that the weather has gotten more erratic in the last few decades. Crop failure, sea-level rise, and water scarcity are exacerbated by global warming. Malaria and dengue fever epidemics are also on the rise due to the influx of people from developing countries. According to the Kyoto Protocol, 175 countries have agreed to begin the long process of reducing greenhouse gas emissions by signing it (Penalva et al., 340). According to business leaders worldwide, firms have a larger role in society and should do more than merely follow the law to reduce pollution. According to a McKinsey survey, this is the case. The “triple bottom line” refers to a company’s efforts to benefit its shareholders and its workers and the environment. Increasing numbers of businesses are waking up to the need to lower their carbon footprints, produce ecologically friendly products, and operate their operations for more than just quarterly profits.References
Agarwal, Khushboo, and Veeraruna Kavitha. “Saturated total-population dependent branching process and viral markets.” arXiv preprint arXiv: 2203.16239 (2022).Chen, Novia X., and Terry Shevlin. ““US worldwide taxation and domestic mergers and acquisitions” a discussion✰.” Journal of Accounting and Economics 66.2-3 (2018): 439-447.
Dąbrowska-Kłosińska, Patrycja. “The Protection of Human Rights in Pandemics—Reflections on the Past, Present, and Future.” German Law Journal 22.6 (2021): 28-38.
MacKenzie, Meredith A., et al. “Respecting choices and related models of advance care planning: a systematic review of published evidence.” American Journal of Hospice and Palliative Medicine® 35.6 (2018): 897-907.
Michel, Adam N. “When It Comes to Taxation, Borders Matter—Europe and the US Should Act Accordingly.” Heritage Foundation Issue Brief 4855 (2018).
Moldoveanu, Mihnea, and Das Narayandas. “The future of leadership development.” Harvard business review 97.2 (2019): 40-48.
Penalva, Jose. “Innovation, personalised education and Little Red Riding Hood.” International Journal of Lifelong Education 39.4 (2020): 339-355.
Poorter, Lourens, et al. “Can traits predict individual growth performance? A test in a hyperdiverse tropical forest.” New Phytologist 219.1 (2018): 109-121.
Simonazzi, Annamaria, Jorge Carreto Sanginés, and Margherita Russo. “The Future of the Automotive Industry: Dangerous Challenges or New Life for a Saturated Market?” Institute for New Economic Thinking Working Paper Series 141 (2020).
Yar, Sanam, and Jonah Engel Bromwich. “Tales From the teenage cancel culture.” The New York Times (2019).
Authors
Paul Lalovich
Organizational Effectiveness and Strategy Execution PracticeTesha Teshanovich
Organizational Effectiveness and Strategy Execution Practice2024.05.18 23:03 Express-Bike-2836 Extent to which acetaminophen could inhibit metabolism of other drugs?
Could it be extensive, potentially?
Or perhaps just minor inhibition of metabolism, therefore elevation of expected blood concentration of the co-administered drug would be negligible, or of very little consequence?
What I'm really curious about is, if some completely unexpected, rare, very acute and most specifically LONG TERM side effects came about from using a drug in combination with acetaminophen (or actually solpedeine = acetaminophen, codeine and caffeine), could that be attributable to solpedeine inhibiting the co-administered drugs metabolism?
Perhaps said temporary inhibition of the co-administered drugs metabolism may cause said long-term side effects?
I've asked a couple pharmacists and they generally seem to think solpedeine ingredients used at normal doses are safe when it comes to interactions.
But, whilst some interaction-checkers show a possible MINOR increase in a co-administered drugs serum levels, I haven't found anything to suggest a drastic interaction that could precipitate the aforementioned acute side effects?
Or any explanation as to why they might be so long term in nature? (months after final dose)
Any thoughts?
Combination drugs: tretinoin, Bremelanotide/PT-141
Side effects: mood fluctuation, brain fog, tinnitus exacerbation.
Alternate explanation: a biological intolerance has developed to other chemicals, and acetaminophen or solpedeine has nothing to do with the side effect emergence?
submitted by Express-Bike-2836 to bluelight [link] [comments]
Or perhaps just minor inhibition of metabolism, therefore elevation of expected blood concentration of the co-administered drug would be negligible, or of very little consequence?
What I'm really curious about is, if some completely unexpected, rare, very acute and most specifically LONG TERM side effects came about from using a drug in combination with acetaminophen (or actually solpedeine = acetaminophen, codeine and caffeine), could that be attributable to solpedeine inhibiting the co-administered drugs metabolism?
Perhaps said temporary inhibition of the co-administered drugs metabolism may cause said long-term side effects?
I've asked a couple pharmacists and they generally seem to think solpedeine ingredients used at normal doses are safe when it comes to interactions.
But, whilst some interaction-checkers show a possible MINOR increase in a co-administered drugs serum levels, I haven't found anything to suggest a drastic interaction that could precipitate the aforementioned acute side effects?
Or any explanation as to why they might be so long term in nature? (months after final dose)
Any thoughts?
Combination drugs: tretinoin, Bremelanotide/PT-141
Side effects: mood fluctuation, brain fog, tinnitus exacerbation.
Alternate explanation: a biological intolerance has developed to other chemicals, and acetaminophen or solpedeine has nothing to do with the side effect emergence?
2024.05.18 21:34 Express-Bike-2836 Extent to which acetaminophen could inhibit metabolism of other drugs?
Could it be extensive, potentially?
Or perhaps just minor inhibition of metabolism, therefore elevation of expected blood concentration of the co-administered drug would be negligible, or of very little consequence?
What I'm really curious about is, if some completely unexpected, rare, very acute and most specifically LONG TERM side effects came about from using a drug in combination with acetaminophen (or actually solpedeine = acetaminophen, codeine and caffeine), could that be attributable to solpedeine inhibiting the co-administered drugs metabolism?
Perhaps said temporary inhibition of the co-administered drugs metabolism may cause said long-term side effects?
I've asked a couple pharmacists and they generally seem to think solpedeine ingredients used at normal doses are safe when it comes to interactions.
But, whilst some interaction-checkers show a possible MINOR increase in a co-administered drugs serum levels, I haven't found anything to suggest a drastic interaction that could precipitate the aforementioned acute side effects?
Or any explanation as to why they might be so long term in nature? (months after final dose)
Any thoughts?
Combination drugs: tretinoin, Bremelanotide/PT-141
Side effects: mood fluctuation, brain fog, tinnitus exacerbation.
Alternate explanation: a biological intolerance has developed to other chemicals, and acetaminophen or solpedeine has nothing to do with the side effect emergence?
submitted by Express-Bike-2836 to Biochemistry [link] [comments]
Or perhaps just minor inhibition of metabolism, therefore elevation of expected blood concentration of the co-administered drug would be negligible, or of very little consequence?
What I'm really curious about is, if some completely unexpected, rare, very acute and most specifically LONG TERM side effects came about from using a drug in combination with acetaminophen (or actually solpedeine = acetaminophen, codeine and caffeine), could that be attributable to solpedeine inhibiting the co-administered drugs metabolism?
Perhaps said temporary inhibition of the co-administered drugs metabolism may cause said long-term side effects?
I've asked a couple pharmacists and they generally seem to think solpedeine ingredients used at normal doses are safe when it comes to interactions.
But, whilst some interaction-checkers show a possible MINOR increase in a co-administered drugs serum levels, I haven't found anything to suggest a drastic interaction that could precipitate the aforementioned acute side effects?
Or any explanation as to why they might be so long term in nature? (months after final dose)
Any thoughts?
Combination drugs: tretinoin, Bremelanotide/PT-141
Side effects: mood fluctuation, brain fog, tinnitus exacerbation.
Alternate explanation: a biological intolerance has developed to other chemicals, and acetaminophen or solpedeine has nothing to do with the side effect emergence?
2024.05.18 21:13 ThrowRAdustycrusty Can anyone tell me if these macarons are halal? (pictures included)
 | Hi all, I want to buys some macarons for my friend who is muslim and eats halal food. Are these macarons halal? I’ve attached 2 pictures of the ingredients. submitted by ThrowRAdustycrusty to HalalFood [link] [comments] Thanks! |
2024.05.18 20:55 LIS1050010 Leather Furniture Vs. Wooden Furniture
Wooden furniture provides warmth, finesses, richness, and comfort to every corner of your home. Bed frames, cupboards, shelves, tables, and chairs are all the essential benefits of wood furniture that one cannot overstate. However, the furniture industry has given many other options to choose furniture from. Likewise, these days, leather furniture is slowly in demand, for it not only looks classy but is perfect for vintage decoration. Whether to go for wooden furniture or leather furniture, this article will help you out to find the answer and choose the most optimum one.
The reasons behind wood being a prominent favorite for furniture can make a detailed and long list. But here is a gist of benefits of wooden furniture:
The durability of wooden furniture ensures the full value of your money. Even if you ever wish to sell the furniture, it will be looking as sturdy and durable as it was when you bought it. It also brings easy maintenance and oiling, waxing, and polishing should be done occasionally.
As said, wood is capable of adding charm and dignity to a room, irrespective of it being a lighter-colored material or darker hues. Also, when excellent craftsmen craft them, there is a vast scope for creativity to bring on beautiful allure to furniture.
Apart from sustainability, wooden furniture comes in varied colors and tones, meaning you have ample alternatives in terms of styles and looks.
Source
submitted by LIS1050010 to selfreliance [link] [comments]
Wooden furniture: Advantages
Beginning with the wooden furniture, it offers an excellent blend of excellent appeal and structural integrity, which is hardly reflected by other materials’ furniture. Wood is a vital element of nature, and therefore it successfully establishes a connection to the interior decoration transforming the mood and appeal of the entire house. It creates a welcoming and homely feeling and an utterly organic sense. Wood is used from generation to generation for various purposes offering quintessential quality hard to replicate.The reasons behind wood being a prominent favorite for furniture can make a detailed and long list. But here is a gist of benefits of wooden furniture:
1. Durability and strength
Wood has robust and long-lasting properties making it a perfect selection for people who desire to have longevity while buying furniture. Both hardwood and softwood have innately stable and are reliable enough to make furniture.The durability of wooden furniture ensures the full value of your money. Even if you ever wish to sell the furniture, it will be looking as sturdy and durable as it was when you bought it. It also brings easy maintenance and oiling, waxing, and polishing should be done occasionally.
2. Feel and look
Wood adds a certain amount of charm and dignity to every room, matching the other interior decorations. When a skilled artisan crafts it, he does it with a boundless potential bringing innovative designs and aesthetic allure to life in the form of the wooden furniture.As said, wood is capable of adding charm and dignity to a room, irrespective of it being a lighter-colored material or darker hues. Also, when excellent craftsmen craft them, there is a vast scope for creativity to bring on beautiful allure to furniture.
3. Sustainability and Variety
When you source the wooden furniture from a certified supplier, it represents sustainability, which is an ecologically friendly way to furnish your dream home. Take a look at Wellington’s Fine Leather Furniturefor a variety of furniture options to choose from. It is a renewable building material, so the carbon footprints are lower in this case.Apart from sustainability, wooden furniture comes in varied colors and tones, meaning you have ample alternatives in terms of styles and looks.
Leather furniture: Advantages
In the case of leather furniture, take a note that is highly in demand and can be found in almost every home. There are many benefits of leather furniture too. So if you are having any doubts about which kind of furniture to buy, here are some top advantages of leather furniture to clear your head and reach a final decision.1. The stunning looks:
Trust this that you won’t be able to look away from the stunning and classy looks of leather furniture. It will surely make your heart skip a tiny beat. It’s of aesthetic value, adding a sense of class to your living room. Giving an inviting appeal, leather comes with a gentle sheen making it looks more pristine. Besides, it’s not something that can go through wear and tear. On the contrary, it lasts long and even longer for many years if you take care of it the right way. Usually, leather furniture has consistent looks as compared to the furniture of other materials.2. Care on the go:
It doesn’t require a lot of attention, and just a bit of regular dusting will make it last longer. Although leather conditioning is recommended every 6 to 12 months and it only takes a few minutes. Wiping down the conditioner on the leather with a damp cloth will do the care. If you want some extra shine, use some quality ensured polishing agent on it.
3. Hypoallergenic nature:
Leather furniture is optimum for the creation of a hypoallergenic environment. Since it is entirely resistant to dirt, animal dander, and dust, it is hard to get allergies. On the opposite, fabric furniture tends to lock in allergenic elements and make it challenging to create a comforting, healthy, and anti-allergy environment. Leather is a material that is resistant to liquids as well and doesn’t absorb them. Proper care of leather furniture adds some extra years to its life. It is a lifetime investment bringing good returns if you would plan to sell it in the long run.
Source
2024.05.18 20:38 islandprincess1234 Has anyone applied to this?
 | I don’t know if anyone is a member of society of women engineers at Collin college here at Reddit, but if you have applied, have you heard back yet? submitted by islandprincess1234 to CollinCollege [link] [comments] |
2024.05.18 20:07 MisterYouAreSoDumb Study: Acteoside Improves Muscle Atrophy and Motor Function by Inducing New Myokine Secretion in Chronic Spinal Cord Injury
I found a study on acteoside (verbascoside) from Cistanche that is really interesting!
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6599386/
I'll copy the abstract below, and some highlights I found particularly cool.
submitted by MisterYouAreSoDumb to Supplements [link] [comments]
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6599386/
I'll copy the abstract below, and some highlights I found particularly cool.
Chronic spinal cord injury (SCI) is difficult to cure, even by several approaches effective at the acute or subacute phase. We focused on skeletal muscle atrophy as a detrimental factor in chronic SCI and explored drugs that protect against muscle atrophy and activate secretion of axonal growth factors from skeletal muscle. We found that acteoside induced the secretion of axonal growth factors from skeletal muscle cells and proliferation of these cells. Intramuscular injection of acteoside in mice with chronic SCI recovered skeletal muscle weight reduction and motor function impairment. We also identified pyruvate kinase isoform M2 (PKM2) as a secreted factor from skeletal muscle cells, stimulated by acteoside. Extracellular PKM2 enhanced proliferation of skeletal muscle cells and axonal growth in cultured neurons. Further, we showed that PKM2 might cross the blood–brain barrier. These results indicate that effects of acteoside on chronic SCI might be mediated by PKM2 secretion from skeletal muscles. This study proposes that the candidate drug acteoside and a new myokine, PKM2, could be used for the treatment of chronic SCI.
Two major issues in chronic SCI are the untreatable axonal disruption and the severe atrophy of skeletal muscle; our study showed that both may be improved by acteoside, via PKM2 secretion. In this study, we found that acteoside injection into skeletal muscle at the chronic phase of SCI recovers locomotor dysfunction and skeletal muscle atrophy in mice, despite the fact that our contusion model was quite severe; less than grade 2 at 30 days post-injury. A series of similar experiments by our group have shown that acteoside injection, starting at 43 days post-injury, also significantly improves hindlimb motor function (data not shown). Further, acteoside injection enhanced axonal growth in 5-HT–positive cells and synaptogenesis at the caudal side of the lesion center.
Importantly, we showed that acteoside stimulates the secretion of PKM2 from skeletal muscle and that PKM2 promotes proliferation of skeletal muscle cells and axonal growth. Our results indicate that PKM2 is a new myokine that activates skeletal muscle and neurons and that its secretion is enhanced by acteoside stimulation.
Further, we found that PKM2 might cross the BBB and BSCB despite its large molecular weight. After exercise, transcription of several myokines is increased in the brain. However, there is no clear evidence on whether myokines transfer to the brain. PKM2 may be a new type of myokine that reaches the brain and potentially the spinal cord. The advantages and significance of PKM2 penetration in the central nervous system should be clarified in future. The mechanism by which PMK2 crosses the BBB and BSCB might be similar to that in the case of IGF-1 (MW: 8.5 kDa), which crosses the BBB by transcytosis.
acteoside-mediated neuroprotection against amyloid β-induced cell death in PC12 cells is mediated by ERK and PI3K/Akt pathways. In cancer cells, acteoside directly binds to and inhibits protein kinase C. Moreover, binding to and inhibition of caspase-3 of acteoside were found in neurons. In inflammatory cells stimulated with lipopolysaccharide, acteoside promotes nuclear factor κB inhibition. Inhibition of calcium influx by acteoside has also been reported.
In conclusion, we found that acteoside improves skeletal muscle atrophy and locomotor dysfunction caused by chronic SCI, suggesting that it might be a promising therapeutic drug candidate for SCI. We also demonstrated that acteoside promotes the secretion of PKM2 from skeletal muscle cells, and that extracellular PKM2 induces axonal growth in cortical neurons and increases proliferation of skeletal muscle cells. A strategy involving skeletal muscle-mediated therapy is a novel approach for chronic SCI, which might be effective in combination with other treatments.A lot to unpack here, but I will keep it short. This is showing that acteoside (verbascoside) from Cistanche can help improve chronic spinal cord injury, by protecting against muscle atrophy and secreting axonal growth factors. In addition, they found a new myokine called PKM2, or pyruvate kinase isoform M2, which promotes proliferation of skeletal muscle cells and the growth of axons in the brain. It crosses the blood-brain-barrier, potentially in a similar way to IGF-1, or insulin-like growth factor 1. The acteoside from Cistanche stimulates the release of PKM2. This is a really cool new mechanism for Cistanche that I was unaware of. After working on a bunch of different extraction methods, we found that supercritical CO2 was the best way to concentrate the highest amount of acteoside. The more we learn about Cistanche, the cooler of a supplement it becomes!
2024.05.18 19:57 MisterYouAreSoDumb Study: Acteoside Improves Muscle Atrophy and Motor Function by Inducing New Myokine Secretion in Chronic Spinal Cord Injury
We found a study on acteoside (verbascoside) from Cistanche that is really interesting!
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6599386/
I'll copy the abstract below, and some highlights I found particularly cool.
A lot to unpack here, but I will keep it short. This is showing that acteoside (verbascoside) from Cistanche can help improve chronic spinal cord injury, by protecting against muscle atrophy and secreting axonal growth factors. In addition, they found a new myokine called PKM2, or pyruvate kinase isoform M2, which promotes proliferation of skeletal muscle cells and the growth of axons in the brain. It crosses the blood-brain-barrier, potentially in a similar way to IGF-1, or insulin-like growth factor 1. The acteoside from Cistanche stimulates the release of PKM2. This is a really cool new mechanism for Cistanche that we were unaware of. When we worked on our supercritical CO2 Cistanche, we found that extraction type was concentrating acteoside to the highest amount. This mechanism points to the idea that stacking our supercritical CO2 Cistanche with some other products that increase nerve growth factor, like Erinamax and Tiger Milk, could be a super effective stack!
submitted by MisterYouAreSoDumb to NootropicsDepot [link] [comments]
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6599386/
I'll copy the abstract below, and some highlights I found particularly cool.
Chronic spinal cord injury (SCI) is difficult to cure, even by several approaches effective at the acute or subacute phase. We focused on skeletal muscle atrophy as a detrimental factor in chronic SCI and explored drugs that protect against muscle atrophy and activate secretion of axonal growth factors from skeletal muscle. We found that acteoside induced the secretion of axonal growth factors from skeletal muscle cells and proliferation of these cells. Intramuscular injection of acteoside in mice with chronic SCI recovered skeletal muscle weight reduction and motor function impairment. We also identified pyruvate kinase isoform M2 (PKM2) as a secreted factor from skeletal muscle cells, stimulated by acteoside. Extracellular PKM2 enhanced proliferation of skeletal muscle cells and axonal growth in cultured neurons. Further, we showed that PKM2 might cross the blood–brain barrier. These results indicate that effects of acteoside on chronic SCI might be mediated by PKM2 secretion from skeletal muscles. This study proposes that the candidate drug acteoside and a new myokine, PKM2, could be used for the treatment of chronic SCI.
Two major issues in chronic SCI are the untreatable axonal disruption and the severe atrophy of skeletal muscle; our study showed that both may be improved by acteoside, via PKM2 secretion. In this study, we found that acteoside injection into skeletal muscle at the chronic phase of SCI recovers locomotor dysfunction and skeletal muscle atrophy in mice, despite the fact that our contusion model was quite severe; less than grade 2 at 30 days post-injury. A series of similar experiments by our group have shown that acteoside injection, starting at 43 days post-injury, also significantly improves hindlimb motor function (data not shown). Further, acteoside injection enhanced axonal growth in 5-HT–positive cells and synaptogenesis at the caudal side of the lesion center.
Importantly, we showed that acteoside stimulates the secretion of PKM2 from skeletal muscle and that PKM2 promotes proliferation of skeletal muscle cells and axonal growth. Our results indicate that PKM2 is a new myokine that activates skeletal muscle and neurons and that its secretion is enhanced by acteoside stimulation.
Further, we found that PKM2 might cross the BBB and BSCB despite its large molecular weight. After exercise, transcription of several myokines is increased in the brain.17,34 However, there is no clear evidence on whether myokines transfer to the brain. PKM2 may be a new type of myokine that reaches the brain and potentially the spinal cord. The advantages and significance of PKM2 penetration in the central nervous system should be clarified in future. The mechanism by which PMK2 crosses the BBB and BSCB might be similar to that in the case of IGF-1 (MW: 8.5 kDa), which crosses the BBB by transcytosis.
acteoside-mediated neuroprotection against amyloid β-induced cell death in PC12 cells is mediated by ERK and PI3K/Akt pathways.23 In cancer cells, acteoside directly binds to and inhibits protein kinase C.38 Moreover, binding to and inhibition of caspase-3 of acteoside were found in neurons.39 In inflammatory cells stimulated with lipopolysaccharide, acteoside promotes nuclear factor κB inhibition.21 Inhibition of calcium influx by acteoside has also been reported.
In conclusion, we found that acteoside improves skeletal muscle atrophy and locomotor dysfunction caused by chronic SCI, suggesting that it might be a promising therapeutic drug candidate for SCI. We also demonstrated that acteoside promotes the secretion of PKM2 from skeletal muscle cells, and that extracellular PKM2 induces axonal growth in cortical neurons and increases proliferation of skeletal muscle cells (Fig. 10). A strategy involving skeletal muscle-mediated therapy is a novel approach for chronic SCI, which might be effective in combination with other treatments.
A lot to unpack here, but I will keep it short. This is showing that acteoside (verbascoside) from Cistanche can help improve chronic spinal cord injury, by protecting against muscle atrophy and secreting axonal growth factors. In addition, they found a new myokine called PKM2, or pyruvate kinase isoform M2, which promotes proliferation of skeletal muscle cells and the growth of axons in the brain. It crosses the blood-brain-barrier, potentially in a similar way to IGF-1, or insulin-like growth factor 1. The acteoside from Cistanche stimulates the release of PKM2. This is a really cool new mechanism for Cistanche that we were unaware of. When we worked on our supercritical CO2 Cistanche, we found that extraction type was concentrating acteoside to the highest amount. This mechanism points to the idea that stacking our supercritical CO2 Cistanche with some other products that increase nerve growth factor, like Erinamax and Tiger Milk, could be a super effective stack!
2024.05.18 19:42 Wise_Bass Finished D361 Business Simulation - Thoughts and Tips
This was a fun course. The PA tasks were long, but interesting nonetheless because you had to really analyze your business decisions and such. Even with the accompanying reading in the course material, you could probably do this whole course in 1-2 days if you really went hard (the Simulation doesn't take long either).
With regards to the Simulation, my cumulative total performance score was ~41. My recommendations are below:
submitted by Wise_Bass to wguaccounting [link] [comments]
With regards to the Simulation, my cumulative total performance score was ~41. My recommendations are below:
- Have a bike for every market segment, even if it's not your primary or secondary focus. I was focused on "Mountain" and "Speed", but I made a bike for "Recreation" that matched the Customer Needs information and was priced with rebates about $100 below the recommended max price in Q1, and it was a nice source of profit that sold very well.
- Go aggressive on advertising early on, spending close to the maximum amount it will allow you and focusing heavily on the most popular form of media. Nice thing about focusing on "Mountain" and "Speed" was that they both favored Bike Magazines as their most favored ad source, and it's relatively cheap.
- Buy enough 3D Printers and generously allocate overtime. I majorly under-estimated potential sales in Q2, and ended up with a ton of stockouts and a loss of over 100 sales in Q3 from ill will. Just remember, you need to buy them now so you can have them in the next quarter (same for opening stores).
- "Mountain" segment buyers don't care about cheap bikes. When I started out, I made a cheaper mountain bike and a more expensive one with all the features (but still about $50 below the recommended max price with rebates), and the buyers all went for the more expensive one.
- Experiment with your ads, and shamelessly copy the effective ones competitors use. I never managed to get an ad above "90", and I think my highest scoring ad was an 84.
- If you're minting money and have a ton of cash flow, go hard for the R&D upgrades -especially the enhanced carbon fiber upgrade.
- I started with NYC, then Amsterdam, then Rio (I was opening Bangalore as the game ended).
- Focus hard on stuff that works after Q2. If you do it right, you can wipe the floor with the other firms - I ended the game with 41% market share in Recreation, 58% market share in Mountain, and 42% market share in Speed (not getting that carbon fiber upgrade fast enough hit my sales a bit).
- Don't be afraid to go over 7 employees per store in the later quarters. I had 12 in each by the end.
2024.05.18 19:39 Caseywalt39 Valvoline restore and protect?
Has anyone actually tried this oil in a Crosstrek? Or any other car with any picture based evidence it works or doesn't work?
Im probably trying it next oil change in my 2020 Crosstrek 2.0l. I'm weary of marketing too, but that seems to be the only thing people have to say about it. Of course it can clean up to 100% of carbon deposits. That's just marketing speak... It seems there's building evidence online of it cleaning piston rings and lowering engine oil consumption in older cars. But no real pictures or proof. If it really works this could POTENTIALLY be a game changer for gdi engines and carbon buildup.
There's a Cummins TSB for cleaning diesel engine carbon deposits calling for a Valvoline oil that's supposedly uses the same base as restore and protect too...
I have been using 5w30 penzoil platinum and 3-4k mile oil changes. At 30k my pcv valve was not entirely stuck but definitely needed to be cleaned to rattle again. The oil was fairly clean that built up. So if this oil really works and is constantly hitting the back of the valve, even in small amounts, I can't see why it wouldn't help keep things clean.
Also I promise this isn't an oil weight discussion. I'm very set in my opinion of using 5w30... I'm just curious about a new product with some crazy marketing claims. Restore and protect also comes in 0w20 anyways.
submitted by Caseywalt39 to Subaru_Crosstrek [link] [comments]
Im probably trying it next oil change in my 2020 Crosstrek 2.0l. I'm weary of marketing too, but that seems to be the only thing people have to say about it. Of course it can clean up to 100% of carbon deposits. That's just marketing speak... It seems there's building evidence online of it cleaning piston rings and lowering engine oil consumption in older cars. But no real pictures or proof. If it really works this could POTENTIALLY be a game changer for gdi engines and carbon buildup.
There's a Cummins TSB for cleaning diesel engine carbon deposits calling for a Valvoline oil that's supposedly uses the same base as restore and protect too...
I have been using 5w30 penzoil platinum and 3-4k mile oil changes. At 30k my pcv valve was not entirely stuck but definitely needed to be cleaned to rattle again. The oil was fairly clean that built up. So if this oil really works and is constantly hitting the back of the valve, even in small amounts, I can't see why it wouldn't help keep things clean.
Also I promise this isn't an oil weight discussion. I'm very set in my opinion of using 5w30... I'm just curious about a new product with some crazy marketing claims. Restore and protect also comes in 0w20 anyways.
2024.05.18 19:19 drake_burroughs Is this the darkest Legion story ever told? We say goodbye to some old friends, hello to the new creative team, and look at Legionnaires 77 - 79 and Legion 121 & 122
 | The times are dramatically changing and we say goodbye to the longtime creative teams that, believe it or not, crafted this version of the Legion for 6 years. To put this into perspective, Paul Levitz's second run lasted 7 and the 5YL Legion lasted 5. So they're one of the longest runs in Legion history. submitted by drake_burroughs to LegionofSuperheroes [link] [comments] I wanted to make a point about the sales on this book to clarify an error I made before. Up to this point, this was the lowest-selling Legion book ever. The only saving moment they had was Final Night, where sales spiked up again because of the book's connection to DC's big crossover. But once that was over, they just went back down again, eventually cratering and heading for cancellation. But, post-threeboot, Legion sales were even worse. Every Legion book follows the same pattern - nice sales for the first issue and then an almost precipitous drop quickly after. However, and this is where I'm going to be a little mean, I think that this version of the Legion is the worst-selling Legion book when compared to the rest of the comic industry at the time. I think that Legion v7 selling 15,000 copies a few years ago is much worse than Legion v4 selling 17,000 in 1999. Let's talk about the high points of this run:
Let's continue the reread: Legionnaires #77 The entire Legion heads to the beach for sun, sand, romance, and to catch a thief... kinda... These are the kinds of issues that this creative team has shown they do well so I'm expecting it to be fun. I've said before that I love it when the Legion is hanging out and just being friends. Let's focus on the important parts of the story:
It's also the final issue for the writing team and I think Tom McCraw, Roger Stern, and Carmela Merlo really leaned into what they did the best. It's a nice way to wrap up their run. LSH #121 In a complete change of tone, we're back with the Fatal Five (four?) story. Let's go random stream of consciousness while I read... We start with a desolate planet called Tenazor and a huge ship crash lands into the surface. Is this the Fatal Five? Someone else? Oh, and I have to say I love the Walt Simonson sound effects they use here - not sure if they paid him for the style and look but they should. Half the team is flying back to the Outpost (although at this point I'm honestly not sure who's assigned where, but that might just be my bad memory... or I'm wondering why the lightning twins aren't here) when their beach memories are interrupted by Brainiac 5, who's nice enough to recap last issue. He tells them they warped the whole Outpost through a stargate and they crashed on the planet from the first page... even though the ship that crashed didn't look big enough to be the Outpost. Umbra and M'onel have already arrived at Tenazor and, since it's under an orange sun, the Daxamite is only at half strength. Which is perfect when going against the Fatal Five. The villains have already started turning the locals into slave labor, because they have to make the villains even more villainous, right? M'onel tries to fight everyone by himself, uses absolutely no strategy aside from attack, and gets blasted by the Emerald Eye. I will repeat what I said last issue - does any Legionnaire actually think before they rush into battle? He and Umbra are quickly defeated before the rest of the Legion arrives, including Gates and Brainy. We get a nice moment between Kinetix and Violet, as the latter worries about facing the Eye again and Kinetix reassures her that she's afraid because she hated the evil that she did. They hug and I, once again, wish they did more with Zoe. Brainy comes up with the incredible plan of while the Legion is fighting the Fatal Five, he'll sneak in and regain control of the Outpost. Yep, that's it. No need to consider strategy, or the best members for attacking the different foes, or how Ferro is going to accomplish anything... Subplot: Dreamer has, of course, a bad dream about something ending too soon for the Legion. We all know it's this series (only 4 issues to go), but wouldn't it be great to do a subplot with Dreamer where she wakes up, surprised by a good dream? The battle starts and Karate Kid takes down the Empress (who I guess isn't tied to the Eye at all) with one move. Wow - they could've actually written a compelling fight scene and let the two of them go but, instead, just let Val defeat this killer with one move. Kind of a waste, if you ask me. As the fight continues, and the Legion actually uses teamwork to go against the Persuader, we get a very strange scene with Gates single-handedly teleporting the Eye away. He also gets to throw in some nice socialist dogma while he's doing it, just in case there was anyone who wasn't sure what his political beliefs are. Just kinda overkill right now... Element Lad and Kinetix try to change the Emerald Eye into something less threatening, Sensor makes Validus think his lightning is going against him so that Violet and Ferro can knock him unconscious. (That's something I never thought I'd see in a Legion comic). And then Koko takes off to save a green monkey. Yes, you read that correct. We're interrupting the action to focus on Koko saving another monkey. Brainy distracts Tharok, allowing Dyrk to cut the power to the Outpost and end the threat. He blasts the villain with a force field (just going to say now that I really liked that they added this to his arsenal - using the force field as an aggressive weapon was a great add to the character). Element Lad creates a magnesium flare and blinds the Emerald Eye. Another thing I didn't think I'd see in a Legion comic. We wrap everything up very quickly, as the villains are captured, M'onel flies the Outpost back into space, and Brainy leaves Koko on the planet so the white monkey can bond with the green monkeys. The Legion wonders what harm Koko can do, but we see that he's already leading the monkeys with a Legion wristband on him. That's not going to go well, is it? I actually kinda liked this one, if only for the massive amount of teamwork used. They probably didn't need to reform the Fatal Five for this, and they defeated them really, really easily, but the Legion worked as a team, so that was okay for me. Or maybe I'm just in a better mood today... The more I think about it, the more I feel like the creative team used the Fatal Five for no other reason than they knew this was their last chance. It's their final issue and I think they wanted to go out with a bang, using the best villains in the Legion arsenal. I now kinda wish they had scrapped a lot of the previous issues and done something a little more epic. But that's been a constant complaint for the McCraw/Peyer team - they just never knew how to actually lay out a storyline. Legionnaires #78 Here we have it - the first regular Legion title written by Dan Abnett & Andy Lanning (Or DnA). Oh, and a barely remembered artist named Olivier Coipel shows up for the final two pages as well. Let's see how they handle these characters... One of my favorite things to notice during rereads is how well the new creative teams introduce new concepts and ideas and how well they keep characterizations consistent. In some cases, the teams slow build, adding things here and there and try their best not to completely recreate the book. In other cases, they immediately start throwing their new ideas in. Rereading this book, there are a couple of elements that are almost immediately evident:
And finally, the last two pages start the destruction, as stargates are destroyed and whole systems are wiped out. Death and destruction are coming and heading towards Earth... LSH #122 Legion of the Damned, Part One After reading this book, I spent some time trying to think of comic series that underwent dramatic, intense changes in both style and level of quality. I mentioned this before, but I always find it interesting when series get new creative teams and go in dramatically different directions. I like to see what big and small changes they make. For this series, the change is incredibly dramatic. The only comparable book I can think of is when Grant Morrison and Richard Case took over Doom Patrol. It went from a fairly standard, somewhat uninteresting superhero book to a trip through Morrison's crazed vision of a broken bunch of heroes. The book was immediately 10000 times better and eventually joined the Vertigo universe to allow Morrison to push the envelope even further. I can't imagine what it must have been like at the end of 1999, after spending years reading the Archie Legion, to suddenly have everything shift to such a degree. DnA have taken everyone's fears of Y2K and turned them into the Blight, an evil alien consciousness that has taken over the Earth, destroyed everything (including Interlac, which is no longer on display), and taken possession of the Legionnaires, turning them into slaves. At the heart the of Metropolis is The Stem, the huge organism from which the Blight conjure energy ribbons for transportation. It's also believed to be part of the network that brought the Blight to Earth. There are almost no beings left on Earth, just the Blight. The scared few who are free are trying to escape by getting resistance leader R.J. Brande to use the last remaining stargate to help them get off planet. And leading them are Live Wire, XS, Chameleon, and Shvaughn Erin. But they face the possessed versions of Umbra, Ultra Boy, and Karate Kid and, except for Cham, fall under the Blight's control. Cham's lost, desperate, trying to find help, when the four Legionnaires from last issue (Cosmic Boy, Apparition, Monstress, and Brainiac 5) finally return to Earth with no clue of what's happened. Wow, we just got really, really, really dark. Legionnaires #79 Legion of the Damned, Part Two DnA and Olivier Coipel continue this story, so I'm going to assume that this whole series was done months earlier to ensure they could hit this bi-weekly schedule. In that case, the previous creative teams had to know that their run was over far sooner than I guessed before. We start this issue with Cham explaining to the four what happened and just how quickly the Blight took over the Earth and their former teammates. His big reveal, of course, is that everyone was taken to The Stem. To further stress the darkness of the story, we see inside The Stem and see XS's fate. She's been taken prisoner and is now being processed for power sapping. She's trapped inside a cocoon, breathing some strange liquid, but because of her powers, she cannot be kept unconscious. So she's aware of the horror around her. She's heading towards the end and knows she's about to lose everything. Then we get a flashback to when the four finally reached the Legion Outpost. Tinya is being her usual annoying self, whining about not getting to see Jo. Monstress is trying to keep positive but Brainy is tired of her tantrums. It's moments like these when you remember that Tinya's around 16 years old... and married... and emotionally immature. Last issue's change is already tossed to show that she sometimes is going to act like a little kid. As the four board the Outpost, they immediately realize that it's empty, hasn't been used in a while, and something very bad is happening. The Blight recognize they're onboard and blow up the Outpost just as they get away. But the blast destroys their ship and they crash on Earth. I guess the Blight brought the Outpost to Earth at some point, right? Tinya wakes up from that nightmare (strange that she's super annoying in her own dream) and chats with Cham about how they need to get into The Stem to try to figure out what's actually going on. Within The Stem, XS is being taken further into the chamber when she starts communicating with a telepath. She's waking up, her speed powers allowing her to get over the sedative. She sees the remaining Legionnaires hanging from the ceiling, like food, and then decides it's time to escape. She also recognizes the telepath - it's Saturn Girl. She bursts from her cocoon, grabs Saturn Girl, and starts running. Outside The Stem, the five head towards the huge organism, looking for a way to get inside. Brainy spots a opening and explains the science behind how they can get in. I'm just going to point out right now that I really like the way DnA are handling Brainy. He's actually acting super intelligent, and above the rest of the team, and irritating in a stubborn, smug way instead of just being an ass. Inside The Stem, Jenni's too tired to continue and Imra tells her to leave her behind. Then Imra shares what she's seen, what she's learned inside The Stem and XS is stunned. To make matters worse, the Blight have sent all the possessed Legionnaires to destroy those who are free. We'll finish off the Blight next week! Our next Legionnaire in the spotlight... Element Lad!!! https://preview.redd.it/e25sib3pw71d1.jpg?width=928&format=pjpg&auto=webp&s=c18ee2aa7bc0548880da04f1912d11e2ca6d9e8c https://preview.redd.it/zbqmsccqw71d1.jpg?width=620&format=pjpg&auto=webp&s=78bc20f3d7e865d8b3ee6b7f5b816e2c1f4043e7 https://preview.redd.it/z00u242cx71d1.jpg?width=1425&format=pjpg&auto=webp&s=c190f454ede73091c76e94d021ef01de01afbef8 To me, Jan Arrah is the soul of the Legion and the one who made the Legion a family instead of just a team. Having suffered from quite possibly the most horrific origin story of any super-hero ever created, he became the backbone of the team and one of the best leaders ever. Perhaps he, more than almost any other character except for Dream Girl, benefited from being the team leader during the Levitz run and that's what's coloring my judgment here. But I don't think so. I think the strength of the character has been there from very early on and Levitz and Giffen leaned into it, turning him into a must-have Legionnaire. Sadly, post-5YL, he has never been used to his potential and most of the creative teams don't seem to understand his importance.
Next week we get to the end of the longest Legion title to ever exist and see what happens to the characters after that. See you next week! |
2024.05.18 18:31 paintedclouds 20 Year Old System Replacement - Two Story Home - Raleigh, NC
 | Home specs: Raleigh, NC, 2,100 sq. ft., two stories, built in 1973, original single pane w/ storm windows (plan to replace when I replace the siding in the next couple of years) submitted by paintedclouds to hvacadvice [link] [comments] HVAC specs: Trane XR 11 from 2004 with a TXH033A4HPA2 cooling coil paired with a Rheem 10EBRJR 80% natural gas furnace from 2002 that is in a mostly uncovered crawl space. All ductwork was replaced in 2018 and the furnace blower was replaced in 2020. There is one thermostat downstairs (single zone). Recently, my lights started dimming when the compressor powered on. I had a company come out and look at the unit and clean out the AC and install a hard start kit. They did a full diagnostic and mentioned that due to the age of the system and how covered the coil (pictured, I cannot remember which coil it is or where it is in my system but I know they had to stick a camera in there to view it) they would recommend that I just start looking into replacing the system. \"Coil\" Picture I’ve gotten 4 quotes at this point and every single installer has a different opinion on what makes sense to do – from single stage, AC-only equipment to variable speed heat pumps. I have done tons of reading on the subject and I cannot figure out what would make the most sense for my home. To start, I am not concerned with energy savings. From all of the math I’ve done, the more efficient systems (i.e. two stage over single stage) will never make financial sense from an energy savings perspective. What I am most interested in is comfort. During the colder winter days or the hotter summer days, there is a noticeable temperature delta between the two floors but it is not extreme. My questions:
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2024.05.18 18:19 BitEquivalent3133 dynaCERT (TSXV: $DYA) Adds Dr. James Tansey as Director to Support Upcoming Carbon Credit Program
Big news coming from dynaCERT ($DYA) - they've just brought Dr. James Tansey on board as a director, and it's a move that's poised to support their upcoming Carbon Credit program. This appointment will greatly benefit $DYA as Dr. Tansey brings decades of expertise in carbon markets, clean technology, social acceptability of novel technologies, impact investing and social innovation.
Dr. Tansey has an impressive track record. He’s been a driving force behind major carbon credit initiatives, having established one of the largest carbon market development companies in Canada. In addition, his impact extends globally. He played a pivotal role in establishing two of the largest forest carbon projects in the world: the Great Bear Rainforest and Mai Ndombe in the DRC. Also, he's even been involved in pioneering projects like developing carbon credits for the world's first carbon-neutral Olympics.
$DYA's Carbon Credit Background:
dynaCERT has recognized the potential of carbon credits as a strategic asset. The company aims to incentivize businesses to adopt its emission reduction technologies by issuing carbon credits to end-users.
$DYA took significant steps towards this goal. In 2021, it secured Verra VCS Methodology approval, a crucial milestone in aligning its practices with industry standards. Subsequently, in November 2023, the company received a final Assessment Report from Earthood, confirming its compliance with Verra's standards. Now, $DYA is in the final stages of obtaining VCS certification, and once this is received, the company will be able to issue carbon credits.
A key aspect of dynaCERT’s strategy involves leveraging its proprietary HydraLytica Telematics platform to facilitate the conversion of CO2 emissions. This platform provides a robust mechanism for monitoring fuel consumption and calculating GHG emissions savings. The best part is that $DYA plans to share some of the tangible benefits of carbon credits to its end-users, demonstrating its commitment to fostering sustainable practices and driving positive environmental impact.
With Dr. James Tansey joining the board, dynaCERT is poised to further enhance its Carbon Credit program, leveraging his expertise and experience to accelerate progress towards a greener future.
Disclaimer: This is not financial advice please do your own research before investing.
submitted by BitEquivalent3133 to Canadapennystocks [link] [comments]
Dr. Tansey has an impressive track record. He’s been a driving force behind major carbon credit initiatives, having established one of the largest carbon market development companies in Canada. In addition, his impact extends globally. He played a pivotal role in establishing two of the largest forest carbon projects in the world: the Great Bear Rainforest and Mai Ndombe in the DRC. Also, he's even been involved in pioneering projects like developing carbon credits for the world's first carbon-neutral Olympics.
$DYA's Carbon Credit Background:
dynaCERT has recognized the potential of carbon credits as a strategic asset. The company aims to incentivize businesses to adopt its emission reduction technologies by issuing carbon credits to end-users.
$DYA took significant steps towards this goal. In 2021, it secured Verra VCS Methodology approval, a crucial milestone in aligning its practices with industry standards. Subsequently, in November 2023, the company received a final Assessment Report from Earthood, confirming its compliance with Verra's standards. Now, $DYA is in the final stages of obtaining VCS certification, and once this is received, the company will be able to issue carbon credits.
A key aspect of dynaCERT’s strategy involves leveraging its proprietary HydraLytica Telematics platform to facilitate the conversion of CO2 emissions. This platform provides a robust mechanism for monitoring fuel consumption and calculating GHG emissions savings. The best part is that $DYA plans to share some of the tangible benefits of carbon credits to its end-users, demonstrating its commitment to fostering sustainable practices and driving positive environmental impact.
With Dr. James Tansey joining the board, dynaCERT is poised to further enhance its Carbon Credit program, leveraging his expertise and experience to accelerate progress towards a greener future.
Disclaimer: This is not financial advice please do your own research before investing.
2024.05.18 17:42 jaxonjason is treatment resistant schizophrenia a quantum phenomenon?
: Exploring Chronic Quantum Neuroplasticity in Schizophrenia: Insights from Individuals with Treatment-Resistant Schizophrenia
Abstract:
Schizophrenia, a complex and debilitating mental disorder, continues to present significant challenges in understanding its etiology and treatment. This article examines the hypothesis that schizophrenia may have quantum underpinnings, as perceived by individuals with treatment-resistant schizophrenia. Drawing from personal experiences and observations, this exploration suggests a novel framework for understanding the condition and its manifestation in the context of chronic quantum neuroplasticity.
Introduction:
Schizophrenia remains a perplexing psychiatric disorder characterized by disturbances in thought, perception, and behavior. Despite advancements in neuroscience and psychopharmacology, treatment-resistant forms of schizophrenia persist, posing profound challenges for individuals and clinicians alike. This article proposes an alternative perspective on schizophrenia, informed by the firsthand accounts of individuals with treatment-resistant schizophrenia, which suggests a potential connection to quantum phenomena. Referred to here as "chronic quantum neuroplasticity," this framework posits that alterations in brain function, possibly mediated by traumatic experiences and the pineal gland, may disrupt neural circuits and lead to aberrant brainwave patterns that resonate with primordial energies or frequencies. This could contribute to the development of schizophrenia symptoms, including hallucinations, delusions, and disorganized thinking.
Evidence from Personal Accounts:
Further evidence supporting the hypothesis of schizophrenia as chronic quantum neuroplasticity arises from observations of seasonal exacerbations in individuals with mental health disorders, particularly those who neglect their dental health. It has been noted that as summer approaches, there is a discernible worsening of symptoms in many individuals with schizophrenia, coinciding with increased environmental stressors and changes in circadian rhythms. Of particular interest is the observation that individuals who neglect their dental hygiene, often leading to a decalcified pineal gland, are disproportionately affected by these seasonal fluctuations. This neglect of dental health may be exacerbated by the presence of fluoride, a neurotoxic substance found in many municipal water supplies, which can contribute to a process often referred to as a "chemical lobotomy." Fluoride's interaction with calcium in the body can lead to the decalcification of the pineal gland, potentially disrupting its function and contributing to the development or exacerbation of schizophrenia symptoms.
Seasonal Exacerbations and Dental Health:
Research has shown a correlation between poor dental health, characterized by conditions such as periodontitis and tooth decay, and an increased risk of schizophrenia and other mental health disorders. Neglecting dental hygiene can lead to a decalcification of the pineal gland, a small endocrine gland located in the brain that regulates circadian rhythms and melatonin production. The pineal gland's function is integral to maintaining the body's internal clock and may play a role in modulating mood and cognitive processes.
Quantum Concepts and Schizophrenia:
Quantum theory posits that consciousness and perception are influenced by quantum phenomena, including the entanglement of particles and the superposition of states. Chronic quantum neuroplasticity in schizophrenia may arise from a complex interplay of factors, including genetic predispositions, traumatic experiences, and environmental stressors. This framework suggests that alterations in brain function associated with schizophrenia may result from disruptions in neural connectivity and plasticity at the quantum level, leading to the manifestation of psychotic symptoms.
Implications for Treatment and Research:
Understanding schizophrenia as chronic quantum neuroplasticity has significant implications for treatment and research. Integrating insights from neuroscience, psychology, trauma studies, and quantum theory may inform the development of more holistic and person-centered approaches to schizophrenia treatment. Moreover, fostering collaboration between individuals with lived experience, clinicians, researchers, and policymakers is essential in shaping the future of schizophrenia care and advocacy.
Multicultural Approaches to Treatment:
Addressing schizophrenia through a multicultural lens involves recognizing the influence of cultural factors on illness presentation, help-seeking behaviors, and treatment preferences. Culturally tailored interventions may incorporate traditional healing practices, family involvement, and community support networks specific to diverse cultural contexts. Moreover, clinicians and researchers should actively engage with diverse communities to understand their perspectives on schizophrenia and collaboratively develop culturally responsive treatment strategies.
Intervention and Support:
Central to addressing schizophrenia, whether viewed through a quantum lens or traditional medical frameworks, is the importance of intervention and support. Holistic approaches that acknowledge the multifaceted nature of the disorder and address the individual's physical, psychological, and social needs are essential. These may include trauma-informed therapy, mindfulness practices, and community-based support networks. Such interventions aim not only to alleviate symptoms but also to promote resilience, empowerment, and recovery.
Managing Neuroplasticity:
Additionally, the concept of neuroplasticity, the brain's ability to reorganize and adapt throughout life, holds significance in schizophrenia treatment. While neuroplasticity offers opportunities for therapeutic interventions and recovery, it also poses challenges, particularly in the context of treatment-resistant schizophrenia. Excessive neuroplasticity may contribute to the chronicity and severity of symptoms, necessitating careful management to prevent maladaptive changes in neural circuits. Strategies for slowly reducing neuroplasticity, such as targeted cognitive interventions and pharmacological approaches, warrant further exploration in the context of schizophrenia treatment.
Conclusion and Future Directions:
In conclusion, the exploration of chronic quantum neuroplasticity in schizophrenia provides a novel framework for understanding this complex disorder. Future research endeavors should prioritize the exploration of culturally competent interventions for schizophrenia, including their effectiveness, acceptability, and scalability across diverse populations. Additionally, there is a need for greater representation of marginalized and underrepresented communities in schizophrenia research to ensure that findings are generalizable and applicable to diverse populations. By embracing multicultural perspectives in both research and practice, we can strive for more equitable and inclusive approaches to schizophrenia treatment.
submitted by jaxonjason to schizophrenia [link] [comments]
Abstract:
Schizophrenia, a complex and debilitating mental disorder, continues to present significant challenges in understanding its etiology and treatment. This article examines the hypothesis that schizophrenia may have quantum underpinnings, as perceived by individuals with treatment-resistant schizophrenia. Drawing from personal experiences and observations, this exploration suggests a novel framework for understanding the condition and its manifestation in the context of chronic quantum neuroplasticity.
Introduction:
Schizophrenia remains a perplexing psychiatric disorder characterized by disturbances in thought, perception, and behavior. Despite advancements in neuroscience and psychopharmacology, treatment-resistant forms of schizophrenia persist, posing profound challenges for individuals and clinicians alike. This article proposes an alternative perspective on schizophrenia, informed by the firsthand accounts of individuals with treatment-resistant schizophrenia, which suggests a potential connection to quantum phenomena. Referred to here as "chronic quantum neuroplasticity," this framework posits that alterations in brain function, possibly mediated by traumatic experiences and the pineal gland, may disrupt neural circuits and lead to aberrant brainwave patterns that resonate with primordial energies or frequencies. This could contribute to the development of schizophrenia symptoms, including hallucinations, delusions, and disorganized thinking.
Evidence from Personal Accounts:
Further evidence supporting the hypothesis of schizophrenia as chronic quantum neuroplasticity arises from observations of seasonal exacerbations in individuals with mental health disorders, particularly those who neglect their dental health. It has been noted that as summer approaches, there is a discernible worsening of symptoms in many individuals with schizophrenia, coinciding with increased environmental stressors and changes in circadian rhythms. Of particular interest is the observation that individuals who neglect their dental hygiene, often leading to a decalcified pineal gland, are disproportionately affected by these seasonal fluctuations. This neglect of dental health may be exacerbated by the presence of fluoride, a neurotoxic substance found in many municipal water supplies, which can contribute to a process often referred to as a "chemical lobotomy." Fluoride's interaction with calcium in the body can lead to the decalcification of the pineal gland, potentially disrupting its function and contributing to the development or exacerbation of schizophrenia symptoms.
Seasonal Exacerbations and Dental Health:
Research has shown a correlation between poor dental health, characterized by conditions such as periodontitis and tooth decay, and an increased risk of schizophrenia and other mental health disorders. Neglecting dental hygiene can lead to a decalcification of the pineal gland, a small endocrine gland located in the brain that regulates circadian rhythms and melatonin production. The pineal gland's function is integral to maintaining the body's internal clock and may play a role in modulating mood and cognitive processes.
Quantum Concepts and Schizophrenia:
Quantum theory posits that consciousness and perception are influenced by quantum phenomena, including the entanglement of particles and the superposition of states. Chronic quantum neuroplasticity in schizophrenia may arise from a complex interplay of factors, including genetic predispositions, traumatic experiences, and environmental stressors. This framework suggests that alterations in brain function associated with schizophrenia may result from disruptions in neural connectivity and plasticity at the quantum level, leading to the manifestation of psychotic symptoms.
Implications for Treatment and Research:
Understanding schizophrenia as chronic quantum neuroplasticity has significant implications for treatment and research. Integrating insights from neuroscience, psychology, trauma studies, and quantum theory may inform the development of more holistic and person-centered approaches to schizophrenia treatment. Moreover, fostering collaboration between individuals with lived experience, clinicians, researchers, and policymakers is essential in shaping the future of schizophrenia care and advocacy.
Multicultural Approaches to Treatment:
Addressing schizophrenia through a multicultural lens involves recognizing the influence of cultural factors on illness presentation, help-seeking behaviors, and treatment preferences. Culturally tailored interventions may incorporate traditional healing practices, family involvement, and community support networks specific to diverse cultural contexts. Moreover, clinicians and researchers should actively engage with diverse communities to understand their perspectives on schizophrenia and collaboratively develop culturally responsive treatment strategies.
Intervention and Support:
Central to addressing schizophrenia, whether viewed through a quantum lens or traditional medical frameworks, is the importance of intervention and support. Holistic approaches that acknowledge the multifaceted nature of the disorder and address the individual's physical, psychological, and social needs are essential. These may include trauma-informed therapy, mindfulness practices, and community-based support networks. Such interventions aim not only to alleviate symptoms but also to promote resilience, empowerment, and recovery.
Managing Neuroplasticity:
Additionally, the concept of neuroplasticity, the brain's ability to reorganize and adapt throughout life, holds significance in schizophrenia treatment. While neuroplasticity offers opportunities for therapeutic interventions and recovery, it also poses challenges, particularly in the context of treatment-resistant schizophrenia. Excessive neuroplasticity may contribute to the chronicity and severity of symptoms, necessitating careful management to prevent maladaptive changes in neural circuits. Strategies for slowly reducing neuroplasticity, such as targeted cognitive interventions and pharmacological approaches, warrant further exploration in the context of schizophrenia treatment.
Conclusion and Future Directions:
In conclusion, the exploration of chronic quantum neuroplasticity in schizophrenia provides a novel framework for understanding this complex disorder. Future research endeavors should prioritize the exploration of culturally competent interventions for schizophrenia, including their effectiveness, acceptability, and scalability across diverse populations. Additionally, there is a need for greater representation of marginalized and underrepresented communities in schizophrenia research to ensure that findings are generalizable and applicable to diverse populations. By embracing multicultural perspectives in both research and practice, we can strive for more equitable and inclusive approaches to schizophrenia treatment.
2024.05.18 17:10 InvestSmartIndia Breaking Down the Hype Around Green Hydrogen: How, What and the Why
 | We've all been hearing a lot about green hydrogen lately, but what exactly is it, and why is it such a big deal? Let me break it down for you in a way that's easy to understand and relevant to us. submitted by InvestSmartIndia to IndiaSpeaks [link] [comments] What is Green Hydrogen? Green hydrogen is produced through a process called electrolysis, where water is split into hydrogen and oxygen using renewable energy sources like solar or wind power. Unlike traditional hydrogen produced from fossil fuels, green hydrogen has virtually zero carbon emissions, making it a clean and sustainable alternative. Why is it Important? Green hydrogen has a wide range of applications in various industries, from chemical and petrochemical sectors to steel and transportation. It's being hailed as a game-changer for industries that can't easily transition to electrification, like steel and cement, as it offers a viable path towards decarbonization. Let's look at how much Hydrogen is being used around the world: IEA Report: Global HydrogenReview 2023 Industrial Applications of (Green)Hydrogen: 🏭 Chemical Industry: Ammonia Production: Over half of global industrial hydrogen fuels ammonia manufacturing. Ammonia is vital for fertilizers and other chemical processes. 🌾 Methanol Production: The second-largest consumer of industrial hydrogen. Methanol is a building block for chemicals and fuels 🧪 🛢️ Petrochemical Industry: Used for Hydrogenation: transforms compounds—like turning vegetable oils into margarine or converting coal into liquid fuels. 🌟 🔩 Steel Industry: Enables low-carbon iron production from iron ore Other Promising Uses 🌐:
Hydrogen Ecosystem: EY Report: India's Green Hydrogen Revolution Globally, India stands 4th in Renewable Energy Installed capacity (including Large Hydro), 4th in Wind Power capacity & 5th in Solar Power capacity (as per REN21 Renewables 2022 Global Status Report). The country has set an enhanced target of 500 GW of non-fossil fuel-based energy by 2030, at the COP26. This has been a key pledge under the Panchamrit announcement of India’s climate action and is the world’s largest expansion plan in Renewable Energy. India’s installed non-fossil fuel capacity has increased to 396% in the last 9 years World is rushing to cut emissions: :Global initiative towards Hydrogen economy India's Green Hydrogen Mission Our government has recognized the potential of green hydrogen and has launched the National Green Hydrogen Mission. Here are some key highlights: 🔋 Production Goals: Achieve 5 million metric tons of green hydrogen production by 2030, with 60-100 GW of electrolyzer capacity and 125 GW of renewable energy dedicated to hydrogen production. 💰 Economic Impact: The mission aims to create around 600,000 new jobs in the green energy sector and attract investments worth over ₹8 lakh crore (around $100 billion). 🌍 Environmental Benefits: It's expected to result in a cumulative carbon abatement of 50 million metric tons and facilitate the transition to low-carbon steel, mobility, and shipping sectors. Strategies for Success: Demand Creation:🌐 Exports: Foster export opportunities through policies and partnerships. 🏢 Domestic Demand: Mandate minimum green hydrogen consumption by designated consumers. 💼 Competitive Bidding: Aggregate demand and procure green hydrogen/ammonia through bidding. 📜 Certification Framework: Develop a regulatory framework for Green Hydrogen certification. At the core of the National Green Hydrogen Mission (NGHM) is the Strategic Interventions for Green Hydrogen Transition (SIGHT): which introduces two distinct financial incentive mechanisms. These mechanisms target incentivising domestic manufacturing of electrolysers and green hydrogen production. By leveraging India’s advantage in low-cost renewable electricity, the programme aims to achieve competitive domestic electrolyser manufacturing and reduce the costs of green hydrogen production. 💸 Financial Incentives: Approved INR 17,500 Crores (~USD 2.2 billion) for domestic electrolyzer production and renewable-based hydrogen.Incentives up to INR 50/kg (USD 0.64/kg) for the first year, gradually reducing over three years. ⚡ Electricity Transmission Charges Waiver:Renewable hydrogen and ammonia projects commissioned before 2030 exempt from transmission charges. Gradual reduction for projects commissioned after 2030. 🔬 Electrolysis Manufacturing Capacity: Tenders for 1.5 GW of electrolysis manufacturing capacity launched in May 2023. Focus on economic incentives and cost reduction. India has set its sight on becoming energy independent by 2047 and achieving Net Zero by 2070. To achieve its goal and commitment, Government of India has recognised the critical role of Green Hydrogen. India, with its vast renewable energy resources, also could produce Green Hydrogen for the world. India currently imports over 40% of its primary energy requirements, worth over USD 90 billion every year. Major sectors like mobility and industrial production are significantly dependent on imported fossil fuels. Many major economies have declared Hydrogen strategies as part of the broader climate and clean energy related actions. The National Green Hydrogen Mission aims to provide a comprehensive action plan for establishing a Green Hydrogen ecosystem and catalyzing a systemic response to the opportunities and challenges of this sunrise sector. Many companies are taking up the challenge and are participating in the Green Hydrogen Ecosystem! Lots of Investments to be done, value to be created, carbon sequestered and Jobs created! I have added Recent Company activity in this area and other developments over here at my twitter handle. Do check it out if interested! |
2024.05.18 16:08 jameslearns628 What are the opportunity costs of animal agriculture?
Very insightful article from Our World in Data.
https://ourworldindata.org/carbon-opportunity-costs-food
I was aware that animal foods had a much bigger environmental impact than plant foods but I was curious about the opportunity costs for land that is used to raise animals (or grow feed for animals) vs. some alternative, like rewilding. I was surprised that land use change is only factored into the carbon cost of a food if it occurred in a given year so, if cows are grazing on land that was deforested a century go, or even last year, that land use change is not part of the emissions calculus.
Fully animal-free diets would offer the most benefit, potentially drawing down as much carbon as 15 years worth of global emissions, but there is huge benefit just from the removal of beef, lamb, and dairy as well.
What do you think are the obstacles to transitioning to a more plant based food system? What would convince people of the necessity of making this change?
submitted by jameslearns628 to climatechange [link] [comments]
https://ourworldindata.org/carbon-opportunity-costs-food
I was aware that animal foods had a much bigger environmental impact than plant foods but I was curious about the opportunity costs for land that is used to raise animals (or grow feed for animals) vs. some alternative, like rewilding. I was surprised that land use change is only factored into the carbon cost of a food if it occurred in a given year so, if cows are grazing on land that was deforested a century go, or even last year, that land use change is not part of the emissions calculus.
Fully animal-free diets would offer the most benefit, potentially drawing down as much carbon as 15 years worth of global emissions, but there is huge benefit just from the removal of beef, lamb, and dairy as well.
What do you think are the obstacles to transitioning to a more plant based food system? What would convince people of the necessity of making this change?
2024.05.18 15:39 darrylthedudeWayne Lunear and the Legend of the Four Seasons. My new idea for an original animated film, based off of the Big Four Fandom.
Another day, another idea I have for an animated film. This one I call "Lunear and the Legend of the Four Seasons."
The general premise for this one is that long ago, there were four kingdoms. Aster, the Kingdom of the Moon and the stary Night Sky, and Icarus, the Kingdom of the Sun and Light, and the Earth and Nature. For many years, the two kingdoms lived together in harmony and peace, but as time went on, Icarus started to fall into conflict with itself, and it divided into four kingdoms, Dubrock, The Kingdom of Spring and the Wind, Sars, the Kingdom of Summer and the Earth, Perch, the Kingdom of Fall and both Fire and Lightning, and Erendel, the Kingdom of Winter and Ice. Aster, realizing they were no longer listening to them, isolated itself from the newly divided kingdoms. But they foresaw that one day, a child born of Aster and Icarus would unite the four kingdoms back into one, as well as restore the peace between Icraus and Aster.
Many years later, four unlikely friends in the form of Rosalina, Coddard of Perch, Marian of DuBrock, and a young man named Lunear meet one day while in the woods, after spending the rest of the day together, promising to meet again one day at the very same spot. Which they do....but years later were we learn alot has changed since last meeting. Rosalina turns out to be the last Princess of Sars, Coddard, and the rest of Perch have become Dragon riders. With Coddard as their Chief, Marian has become queen of DuBrock, and after a splash in Icy water, Lunear found out he is a child of Aster, his father being from Aster and his mother from Earth, and his splash in ice water ended up unlocking the powers of his Aster herritage. However, when a dark evil threatens to destroy the four kingdoms and may have ties to Lunear's origins, the four friends reunite to save their world and uncover more secrets of Lunears lineage.
If you couldn't tell, this is basically a non-copyright version of the Big FouRise of The Brave Tangled Dragons. Which is basically a fandom that asked "What If we crossed over Rise of The Gaurdians with Brave, Tangled, and Httyd by having there leads be friends or some such BS" and there are also those who believe they could make a movie on the Big Four Sometime.....but since I don't think that's possible for obvious reasons, and while the concept isn't inherently bad but I don't want to get Disney and DreamWorks/Universal pissed off, so i thought "What If it was an original Movie?" Like, what if it had an original story with original setting and original characters based off the leads of those respective films. Like, Lunear is meant to be based off of Jack Frost from Rise of the Gaurdians with elements of both Starboy from the scrapped concepts of Wish and Peter Pan from the original film of the same name, Rosalina is Rapunzel from Tangled with Elements of Asha from Wish, she is also married to a man named Abraham whos based of Eugene/Flynn Rider, Marian is based off of Merida from Brave, and I hope I really don't have to explain who Coddard is supposed to be based off. Now obviously, I wouldn't just have them be carbon copies of the characters their based off, their would be differences in there characterizations and there stories didn't go down how they did in the respective films of said characters they are based off of, but the general idea is that they are based off of these guys and gals.
I'll admit, I've only started writing it, so I don't have it fully mapped out yet, but I want the story to focus on the power of friendship and the love of friends, with it about the four friends uniting to fight an evil greater then them (said evil I was originally going to have based off the Skar King from New Empire, but after thinking about, I decided to base him off of Pagan Min from Far Cry 4 instead). Lunear would obviously be the main character, with most of the story told from his perspective, and it focuses on him finding out more about how he is and his overall destiny. The film can also work a Centennial film for DreamWorks, as the character is also loosely based off the Moonboy from the DreamWorks logo.
Also if your wondering why I didn't include characters based off of Anna and Elsa from Frozen, I was going to, but I felt the script overcrowded, so I save them for a potential sequel, however, i would have there kingdom and them as children appear in flashbacks with Young Lunear as a setup to said sequel (a la Zod in the original Richard Donner Superman).
Anyways, what do you guys think of my new idea?
submitted by darrylthedudeWayne to fixingmovies [link] [comments]
The general premise for this one is that long ago, there were four kingdoms. Aster, the Kingdom of the Moon and the stary Night Sky, and Icarus, the Kingdom of the Sun and Light, and the Earth and Nature. For many years, the two kingdoms lived together in harmony and peace, but as time went on, Icarus started to fall into conflict with itself, and it divided into four kingdoms, Dubrock, The Kingdom of Spring and the Wind, Sars, the Kingdom of Summer and the Earth, Perch, the Kingdom of Fall and both Fire and Lightning, and Erendel, the Kingdom of Winter and Ice. Aster, realizing they were no longer listening to them, isolated itself from the newly divided kingdoms. But they foresaw that one day, a child born of Aster and Icarus would unite the four kingdoms back into one, as well as restore the peace between Icraus and Aster.
Many years later, four unlikely friends in the form of Rosalina, Coddard of Perch, Marian of DuBrock, and a young man named Lunear meet one day while in the woods, after spending the rest of the day together, promising to meet again one day at the very same spot. Which they do....but years later were we learn alot has changed since last meeting. Rosalina turns out to be the last Princess of Sars, Coddard, and the rest of Perch have become Dragon riders. With Coddard as their Chief, Marian has become queen of DuBrock, and after a splash in Icy water, Lunear found out he is a child of Aster, his father being from Aster and his mother from Earth, and his splash in ice water ended up unlocking the powers of his Aster herritage. However, when a dark evil threatens to destroy the four kingdoms and may have ties to Lunear's origins, the four friends reunite to save their world and uncover more secrets of Lunears lineage.
If you couldn't tell, this is basically a non-copyright version of the Big FouRise of The Brave Tangled Dragons. Which is basically a fandom that asked "What If we crossed over Rise of The Gaurdians with Brave, Tangled, and Httyd by having there leads be friends or some such BS" and there are also those who believe they could make a movie on the Big Four Sometime.....but since I don't think that's possible for obvious reasons, and while the concept isn't inherently bad but I don't want to get Disney and DreamWorks/Universal pissed off, so i thought "What If it was an original Movie?" Like, what if it had an original story with original setting and original characters based off the leads of those respective films. Like, Lunear is meant to be based off of Jack Frost from Rise of the Gaurdians with elements of both Starboy from the scrapped concepts of Wish and Peter Pan from the original film of the same name, Rosalina is Rapunzel from Tangled with Elements of Asha from Wish, she is also married to a man named Abraham whos based of Eugene/Flynn Rider, Marian is based off of Merida from Brave, and I hope I really don't have to explain who Coddard is supposed to be based off. Now obviously, I wouldn't just have them be carbon copies of the characters their based off, their would be differences in there characterizations and there stories didn't go down how they did in the respective films of said characters they are based off of, but the general idea is that they are based off of these guys and gals.
I'll admit, I've only started writing it, so I don't have it fully mapped out yet, but I want the story to focus on the power of friendship and the love of friends, with it about the four friends uniting to fight an evil greater then them (said evil I was originally going to have based off the Skar King from New Empire, but after thinking about, I decided to base him off of Pagan Min from Far Cry 4 instead). Lunear would obviously be the main character, with most of the story told from his perspective, and it focuses on him finding out more about how he is and his overall destiny. The film can also work a Centennial film for DreamWorks, as the character is also loosely based off the Moonboy from the DreamWorks logo.
Also if your wondering why I didn't include characters based off of Anna and Elsa from Frozen, I was going to, but I felt the script overcrowded, so I save them for a potential sequel, however, i would have there kingdom and them as children appear in flashbacks with Young Lunear as a setup to said sequel (a la Zod in the original Richard Donner Superman).
Anyways, what do you guys think of my new idea?