Tender lymph nodes armpit
Tropical Parasite?
2024.05.19 20:10 Few_Tomatillo2624 Tropical Parasite?
37f 5ft 6 110pounds For the past 2.5 years I have been extremely unwell, mostly bedbound in extreme pain. I returned from the tropics feeling very unwell, with weight loss, bloody stool and severe fatigue. I also had a swollen lymph node in my groin. I had lots of tests and they could not find a thing . I started to see what I thought was parasites in my stool. A doctor prescribed me albendazole. The day after taking it, the lymph node exploded and I started to feel extreme crawling all over my body. I have been trying to work out what was going on ever since. I’m certain I have a systemic infection but all my bloods responded negatively to antibodies. To give my full history, I have lived in a lot tropical countries over 20 years including south east Asia, south India and south and Central America. I have travelled extensively. I’ve been unwell on and off for 16 years and was never tested for infections thoroughly until 2021. Only stool tests and fbc. My symptoms are as follows: - sensations in my veins - feels like rushing / pumping - collapsed / indented veins in the head and face (diagnosed) - ongoing hematuria - extreme groin pain - extreme head pain in veins / tissues - progressive subdermal lumps on pubic area - numbness and ‘dead arms’ - puffy arms - lumpy breasts with sudden prominent veins - severe fatigue
After delving into a tonne of research it has become apparent than only 3 infections can cause systemic infection -Strongoloides, Filariasis and Schistosomiasis. Schistomiasis has been ruled out through urine and cystoscopy. Last month I spoke to a microbiologist (abroad) who I told I suspected an infection. She asked me if I was immune suppressed. I had taken immune suppressants on and off for a while, specifically before this infection got crazy. I also have chronic uti symptoms and occasional acute / severe UTIs. I’ve had to take multiple extended antibiotics in the past - last year I had to take them for 5 months. I was looking into these infections and it seems that steroids can prevent an immune response and can also impact antibody / eosinophil response. What’s more is I found a tonne of case studies where people are diagnosed with filariasis without antibodies or esoniphils. It also says on medical literature that the antibody does not rule out infection. It seems to be a very immune modulating parasite and is even capable of preventing sepsis. Im wondering if perhaps my antibodies response is not working? I cannot convince any of my doctors that I could have this disease, despite being very exposed and having classic progressive symptoms. Therefore they will not do the gold standard microfilaria testing at night. I have lived a very active lifestyle since my early 20s despite having bouts of fatigue and there is no way I’d be this sick if there wasn’t something wrong. I’ve had confirmed parasites come out before also. Doctors keeps saying my symptoms are ‘mysterious’, but will not properly test me for this infection. Does anyone have any suggestions of what I can do? Should I ask to biopsy the subdermal lumps down below ? I know in india testicular lumps are a pretty common sign of the disease. I’d be grateful for any advice. 🙏🏻
submitted by Few_Tomatillo2624 to AskDocs [link] [comments]
After delving into a tonne of research it has become apparent than only 3 infections can cause systemic infection -Strongoloides, Filariasis and Schistosomiasis. Schistomiasis has been ruled out through urine and cystoscopy. Last month I spoke to a microbiologist (abroad) who I told I suspected an infection. She asked me if I was immune suppressed. I had taken immune suppressants on and off for a while, specifically before this infection got crazy. I also have chronic uti symptoms and occasional acute / severe UTIs. I’ve had to take multiple extended antibiotics in the past - last year I had to take them for 5 months. I was looking into these infections and it seems that steroids can prevent an immune response and can also impact antibody / eosinophil response. What’s more is I found a tonne of case studies where people are diagnosed with filariasis without antibodies or esoniphils. It also says on medical literature that the antibody does not rule out infection. It seems to be a very immune modulating parasite and is even capable of preventing sepsis. Im wondering if perhaps my antibodies response is not working? I cannot convince any of my doctors that I could have this disease, despite being very exposed and having classic progressive symptoms. Therefore they will not do the gold standard microfilaria testing at night. I have lived a very active lifestyle since my early 20s despite having bouts of fatigue and there is no way I’d be this sick if there wasn’t something wrong. I’ve had confirmed parasites come out before also. Doctors keeps saying my symptoms are ‘mysterious’, but will not properly test me for this infection. Does anyone have any suggestions of what I can do? Should I ask to biopsy the subdermal lumps down below ? I know in india testicular lumps are a pretty common sign of the disease. I’d be grateful for any advice. 🙏🏻
2024.05.19 20:05 shyfawns Help me understand a surgery and illness I had in 2012?
Hello, looking for some thoughts on what was wrong with me, and what happened during a surgery I experienced in 2012
Context:
I was a 15 year old female, in an Australian hospital. Getting access to the medical records involves a lot of steps I’m not fully brave enough to do.
I hadn’t been diagnosed with any chronic/acute physical ailments prior to becoming unwell. I had been diagnosed with depression & anxiety and was taking fluoxetine. I had my tonsils removed due to frequent tonsillitis around the same age, but cannot recall if it was before or after this surgery.
I had been self harming, possibly using blades that weren’t the cleanest (but were only used by me)
What happened:
I ate a bacon and egg sandwich for lunch and not long after that, severe abdominal pain started. My mother & I assumed it was indigestion.
After 6+ hours it got to the point where I was struggling to breathe from the pain and was taken to the emergency room.
I was admitted to the ED, morphine reduced the pain a little bit but I started vomiting and then dry heaving/gagging after there was nothing left to throw up.
It was assumed it was my appendix, the rebound test confirmed that. An ultrasound was done but they couldn’t find my appendix. I was admitted to the children’s ward for monitoring. Multiple ultrasounds were done over the few days I was there, but they couldn’t see the appendix so assumed it wasn’t inflamed.
I was due to be discharged after about 3 days, but the night before the pain become incredibly bad again. I woke up at 7am being wheeled away to have surgery.
It was keyhole surgery with 3 incisions in my lower abdomen to remove the appendix. They informed my mum that it would be a simple 30-60 minute procedure.
It ended up taking 6 hours.
Afterwards, the surgeons said my appendix had been fine, but they removed it regardless (I understand this is pretty standard). However, they said that my abdomen was filled with pus and (maybe?) lymph fluid, and they spent hours “hosing it out”
They also mentioned that a gynaecologist had to come in and clean my reproductive organs. I’m not sure if this was an internal clean of the womb or if it was an external clean.
I can’t remember exactly what they ended up saying the cause or diagnosis was, and I’ve always been curious about it and have struggled to find info online. I recall them saying something about my internal lymph nodes being the cause, and referred to it as something that sounded like “lymph adie itis”
Does anyone know what the cause or reason that happened was? Why it took so long for them to clean me out (what exactly happens when they do that?) And what the fluid inside me was? I’ve never had a problem like that again.
Thanks :)
submitted by shyfawns to AskDocs [link] [comments]
Context:
I was a 15 year old female, in an Australian hospital. Getting access to the medical records involves a lot of steps I’m not fully brave enough to do.
I hadn’t been diagnosed with any chronic/acute physical ailments prior to becoming unwell. I had been diagnosed with depression & anxiety and was taking fluoxetine. I had my tonsils removed due to frequent tonsillitis around the same age, but cannot recall if it was before or after this surgery.
I had been self harming, possibly using blades that weren’t the cleanest (but were only used by me)
What happened:
I ate a bacon and egg sandwich for lunch and not long after that, severe abdominal pain started. My mother & I assumed it was indigestion.
After 6+ hours it got to the point where I was struggling to breathe from the pain and was taken to the emergency room.
I was admitted to the ED, morphine reduced the pain a little bit but I started vomiting and then dry heaving/gagging after there was nothing left to throw up.
It was assumed it was my appendix, the rebound test confirmed that. An ultrasound was done but they couldn’t find my appendix. I was admitted to the children’s ward for monitoring. Multiple ultrasounds were done over the few days I was there, but they couldn’t see the appendix so assumed it wasn’t inflamed.
I was due to be discharged after about 3 days, but the night before the pain become incredibly bad again. I woke up at 7am being wheeled away to have surgery.
It was keyhole surgery with 3 incisions in my lower abdomen to remove the appendix. They informed my mum that it would be a simple 30-60 minute procedure.
It ended up taking 6 hours.
Afterwards, the surgeons said my appendix had been fine, but they removed it regardless (I understand this is pretty standard). However, they said that my abdomen was filled with pus and (maybe?) lymph fluid, and they spent hours “hosing it out”
They also mentioned that a gynaecologist had to come in and clean my reproductive organs. I’m not sure if this was an internal clean of the womb or if it was an external clean.
I can’t remember exactly what they ended up saying the cause or diagnosis was, and I’ve always been curious about it and have struggled to find info online. I recall them saying something about my internal lymph nodes being the cause, and referred to it as something that sounded like “lymph adie itis”
Does anyone know what the cause or reason that happened was? Why it took so long for them to clean me out (what exactly happens when they do that?) And what the fluid inside me was? I’ve never had a problem like that again.
Thanks :)
2024.05.19 19:55 prxttygrl Blood Results, anyone know what this might be?
I am a 25 yr old Female, and starting in January, thought I just had an earache. I went into the walk in clinic and they prescribed me some medications for my ear. Couple days later, I started having racing thoughts, bad anxiety, and fatigue, which I went back into the doctor and did blood tests and I had hypercalcemia… Fast forward a couple months, I got an endocrinologist and they did some blood tests and my PTH is low and am now diagnosed with Secondary hypoparathyrodism (my symptoms are being caused by something else)… So with these new results, my blood count is actually fine. Everything looks to be in range, BUT my alpha 1 globulin is on the edge of being high and my beta 1 globulin is on the edge of being low. My calcium and bone tests came back good, but my vitamin A is low. Has anyone seen something like this before??
I am worried because I went for a CT scan of my parathyroid and they found lymph nodes that were inflammed, as well as I get this pain underneath my right armpit that flares up.. I looked these symptoms up and of course its gotten my mind racing. any help would be appreciated! Thank you!
submitted by prxttygrl to DiagnoseMe [link] [comments]
I am worried because I went for a CT scan of my parathyroid and they found lymph nodes that were inflammed, as well as I get this pain underneath my right armpit that flares up.. I looked these symptoms up and of course its gotten my mind racing. any help would be appreciated! Thank you!
2024.05.19 19:54 roccosRevenge Wheezing after eating like I have bronchitis
Could be a symptom of autonomic nervous system?
My other symptoms include:
In august last year I had strong infection, I was sweating by month, extreme fatigue, swollen lymph node under armpit.
Since then I have tons of symptons:
submitted by roccosRevenge to covidlonghaulers [link] [comments]
My other symptoms include:
In august last year I had strong infection, I was sweating by month, extreme fatigue, swollen lymph node under armpit.
Since then I have tons of symptons:
- neuropathic pain in back, deep pain in spine
- right shoulder blade is painful and deep itching, extremely weird tingling pain deep, when I move my arm
- my back feels so messed up I feel asymetric when I walk, when I breathe I feel pain in lot of different places in body
- redness on face, flushing, red ears, heatwaves and warm feeling (mostly at night) - when my face is flushed, symptoms of pins needles burning are the worst
- electric, neuralgic pains in face, head, scalp, pain when I move my eyes deep in face
- body itching, itch deep inside ears, face
- skin on face, scalp, eyelids twitch randomly, like electric shocks
- fatigue, brain fog
- brain zaps
- pins needles in feet, body for example when I put my clothes on
- random warm feelings in legs like hot water in legs
- hives which disappeared mostly
2024.05.19 19:10 rahulshariff Prostate Worries? Feeling the Effects of Age on Your Prostate? The Secret Weapon to Good Prostrate Health
 | Prostate Worries? Feeling the Effects of Age on Your Prostate? The Secret Weapon to Good Prostrate Health submitted by rahulshariff to u/rahulshariff [link] [comments] Image Credit: Pexels Prostrate Problems – A Comprehensive Guide for Men's Health The prostate gland is a walnut-sized organ. The organ is the male reproductive system and helps in sexual function and urination. With age, the prostate undergoes changes that lead to various health concerns. This informative guide explores the most common prostate problems, empowering you with knowledge and promoting early detection and treatment. Understanding the Prostate The prostate gland is below the bladder and surrounds the urethra. A healthy prostate is essential for male fertility and urinary control. Common Prostate Problems Many men experience prostate problems as they age. Here's a closer look at the three most frequent issues:
The exact cause of BPH is unknown, but it's believed to be linked to changes in hormone levels as men age. Here are some factors that increase the risk of BPH:
Early diagnosis of BPH is crucial for effective management. Diagnosis typically involves:
Treatment for BPH depends on how severe the symptoms are. Here are some options:
There are three main types of prostatitis:
The causes of prostatitis vary depending on the type. Here are some potential contributing factors:
Diagnosis of prostatitis often involves:
Treatment for prostatitis depends on the type. Here are common approaches:
Symptoms You will often find no symptoms in the early stages. In later stages, it may cause:
Several factors increase the risk of prostate cancer, including:
Early detection of prostate cancer ensures successful treatment. While the PSA test is commonly used, it could be more foolproof. Here are two critical methods for early detection:
If a PSA test or DRE raises concerns, further tests may be needed, including:
Treatment for prostate cancer will depend on different factors. The factors include the cancer's stage and aggressiveness. Some common approaches include:
While there's no guaranteed way to prevent prostate problems, some lifestyle choices may help:
Prostate problems are a common concern for men as they age. By understanding the different types, their symptoms, and risk factors, you ensure good health. Early detection and treatment help manage prostate problems effectively. Don't hesitate to discuss any concerns with your doctor. Taking charge of your prostate health is crucial towards a healthy and fulfilling life. Feeling Frustrated by Limited Prostate Health Solutions? What if a Targeted Probiotic Approach was Specifically Designed to Support Normal Function? Can This Daily Biotic Be Your Secret Weapon for Optimal Health? (Find Out!) Disclaimer - "The post contains affiliate links. I may earn a commission if you purchase through these links." |
2024.05.19 18:50 Fitgirly357 23F, two swollen lymph nodes under same armpit?
Im a female, 23 years old. Has anyone had any swollen lymph nodes in their armpit? I had one a couple months ago that was uncomfortable, the doctor said it was probably an ingrown hair. Now I have two painful ones in the same armpit. I'm not sick and doesn't look like ingrown hair. They are painful to touch too.
submitted by Fitgirly357 to DiagnoseMe [link] [comments]
2024.05.19 18:49 Fitgirly357 23F, Two lymph nodes swollen in the same armpit?
Im a female, 23 years old. Has anyone had any swollen lymph nodes in their armpit? I had one a couple months ago that was uncomfortable, the doctor said it was probably an ingrown hair. Now I have two painful ones in the same armpit. I'm not sick and doesn't look like ingrown hair. They are painful to touch too.
submitted by Fitgirly357 to AskDocs [link] [comments]
2024.05.19 18:33 LastVehicle599 Recurrence and BRAF+ treatment coming
Hi, here is a brief history and where I am at today. 2016 had an atypical mole on back of shoulder with recommendation for removal. Removed in 6/2017 and pathology found melanoma adjacent to the atypical mole. 8/2017 Had a wide excision and SLN biopsy. Positive SLN. Started every 3mo PET and ultrasound of L axilla (arm pit). 10/2017 Started every 2 week treatment with Optivo for 1 year. Had a port placed due to poor IV access. 9/1018 suspicious lymph node had biopsy and positive. 10/2018: complete axillary lymph node dissection 1 out 19 nodes positive. 10/2018-10/2023 continued PET scans and US every 6 months then annually. 10/2023 5 years no evidence of disease (yay) discharged from oncology 3/2024 found a lump in my arm about 2” from original wide excision scar. 4/2024 PET scan with bright shining tumor at site of lump. 5/2024 wide excision of tumor. Anticipated wound vac placement and skin graft. Luckily the surgeon was able to close. Currently sitting home letting this heal.
Meanwhile oncologist sent original melanoma for additional testing (I didn’t even know they kept the samples that long). It is BRAF positive and now he has mentioned wanting to start me on another treatment for a year. Not sure why this testing wasn’t done 6 years ago. Maybe it didn’t exist then.
Has anyone done targeted treatment for BRAF+ melanoma? I have an appointment in 2 weeks with oncologist. Just want input on what questions to ask.
submitted by LastVehicle599 to melahomies [link] [comments]
Meanwhile oncologist sent original melanoma for additional testing (I didn’t even know they kept the samples that long). It is BRAF positive and now he has mentioned wanting to start me on another treatment for a year. Not sure why this testing wasn’t done 6 years ago. Maybe it didn’t exist then.
Has anyone done targeted treatment for BRAF+ melanoma? I have an appointment in 2 weeks with oncologist. Just want input on what questions to ask.
2024.05.19 17:57 need_help_throawa Any insight would be really helpful and nice.
So I had a random hookup with a biology girl about an year ago. Did a lot of tests for HIV, all negative. Now the thing is I'm having red bumps that leave black spots on arms/back /chest/ thighs. Skin tags around both the eyes are growing out of nowhere. Some wierd spots as well. Lymph nodes behind the ear, occipital one side and recently right at the beck there appears to be some swelling and discomfort. Discomfort in chest. Some red bumps with white head at the middle occurs in the area above the penis( not scrotum not penis, the area of pubes). What can it be? Any help? I've tested for gonno rhea, HSV, Chlamydia, syphilis all negative. Please HELP.
submitted by need_help_throawa to STD [link] [comments]
2024.05.19 17:39 Agitated_Front7197 Really sick after MA 4 days ago
Hello, I had an MA on Wednesday when I took the misoprostol pills. On that day, I was bleeding a lot and cramping and passed some clots. Fast forward, I still have some light bleeding and light cramping. On Friday, I started feeling sick like I would get a fever but my temp never actually went up to 100. Last night, I had really bad congestion, runny nose, muscle ache, swollen lymph nodes, and it was hurting to swallow, and yellow nasal discharge/phlegm. I went to the urgent care this morning to get checked and tested negative for strep throat and doctor said it could be a viral infection. I was not prescribed any antibiotics and was told to take over the counter medication to manage the symptoms. I am just wondering if what I’m feeling could be any way related to my medical abortion. I am worried that I could have an infection or an incomplete abortion and this is how my body is reacting to it. Any thoughts would be appreciated. Has anyone ever experienced something like this.
submitted by Agitated_Front7197 to abortion [link] [comments]
2024.05.19 17:09 neoprofen Delayed gastric emptying on 6 months of ozempic?
Hi! I (20F) have been on ozempic for 6 months now (1.0) due to PCOS, BED and an overweight BMI. For all the reasons I’ve been taking the medication, i’ve had great improvements. I never really had any side effects at all, during most of my treatment. About two months ago the delayed gastric emptying became more noticeable, and, after all, it is part of ozempic. However already at 1 month and half ago things worsened drastically. I ended up going to the ER 3 times in a single week, complaining of constant nausea, chronic pain (which i’ve had for years now, but got significantly worse), low grade fever and other infection signs (extremely swollen lymph nodes). I’ve done several exams (blood, urine, physical), but they couldn’t explain what’s happening. I can barely eat or drink liquids and even taking my usual prescription cause me to throw up. I’ve been trying to get in touch with my endocrinologist without any success (my state is going through a massive flood and it would be even impossible for me to go to his clinic since it’s in another city. Honestly, I can’t even tell if what I am experiencing is related to the medication or not, and I am scared to take a break without confirmation of my endocrinologist. Any advice or contributions are welcomed❤️
submitted by neoprofen to Ozempic [link] [comments]
2024.05.19 17:08 GympieIcedTea 31 And Feeling Like Sophie From Howl's Moving Castle
For those of you that don't know, Sophie is the heroine of a Studio Ghibli movie called Howl's Moving Castle which is adapted from a book by Diane Wynne Jones. Sophie is a young woman that is cursed to be an old woman by the Witch of the Waste. The story is about her trying to break this curse. I was diagnosed with EPr+ HER- IDC on my right breast on 5/1/2024. My first line of treatment will be a unilateral mastectomy which is scheduled for 6/24/2024. My breast surgeon told me I will likely need chemo since I'm so young. I know I would need hormone therapy since I'm EPr+. I've been lurking on this subreddit for the past 2 weeks and every post that I read just makes me more and more depressed and scared. Not only am I worried about stage 4 recurrence and death, I'm also scared of lymphedema from lymph nodes removal, neuropathy from chemo, uterine cancer, vaginal atrophy, heart disease, osteoporosis, early-onset dementia from medically-induced menopause. Not to mention weight gain, depression, hot flashes and all the fun jazz that comes with being a member of the shitty titty committee. I don't feel safe in my body anymore and I can't relate to any of my friends because they are all getting married and having kids while I have cancer. I want to live so badly but I just know my quality of life will drop drastically after I start treatment. I'm not ready to embrace this new chapter in my life and I wish this "curse" will be broken. I want to be pre-cancer me again.
submitted by GympieIcedTea to breastcancer [link] [comments]
2024.05.19 16:26 Living-Treacle7283 so worried 23F
Hi I am a 23F with pretty bad health anxiety it comes and goes.. I noticed soreness by my ear where my ear connects to my face and then a couple days ago I realized there was a lump there after the soreness.. it doesn’t really hurt anymore but I’m so afraid it’s a lymph node which are apparently bad if they don’t hurt.. im going to the dr Monday but I am spiraling..
submitted by Living-Treacle7283 to AskDoctorSmeeee [link] [comments]
2024.05.19 16:14 WalkingHorse Predictive value of radiomic features extracted from primary lung adenocarcinoma in forecasting thoracic lymph node metastasis: a systematic review and meta-analysis BMC Pulmonary Medicine
 | submitted by WalkingHorse to LungCancerSupport [link] [comments] |
2024.05.19 16:09 enemenemoo Terrified of Surgery: Should I Get My Tonsils Removed?
Hello everyone,
I've been dealing with strong acute tonsil infections several times a year for several years. Since about six months ago, these acute infections have subsided, but now I have a latent infection. My tonsils are very irritated, especially in the mornings and evenings. Sometimes my lymph nodes swell, and exercising can make the irritation worse—it's like drinking spiced water, you can really feel your tonsils.
The pain isn't severe, but it's always there, making me constantly aware of the irritation. About a month ago, I had a really bad two-week episode of tonsil pain, but then it went away again.
I have a surgery appointment to get my tonsils removed, but I'm really unsure about it. The surgeon has tried to convince me not to go through with it, and I've already been to the hospital twice and canceled another two times. They've told me all sorts of scary things to make me want to avoid the surgery.
I'm conflicted. I could live with this mild ache and the thought that I'm too scared for the surgery. I could endure 2 to 4 weeks of intense pain a few times a year. But I'm scared of the surgery and I don't know if I should go through with it.
I'm not a severe case, but I've had several infections over the past three years, with the last one and a half years being particularly tough. It's gotten better, and I can live a somewhat normal life again. But this constant throat irritation, the feeling of my tonsils being irritated, and the low-level pain—I don't know if I should accept this for the rest of my life.
I'm really confused... 😭
Any advice or shared experiences would be greatly appreciated. Thank you!
submitted by enemenemoo to Tonsillectomy [link] [comments]
I've been dealing with strong acute tonsil infections several times a year for several years. Since about six months ago, these acute infections have subsided, but now I have a latent infection. My tonsils are very irritated, especially in the mornings and evenings. Sometimes my lymph nodes swell, and exercising can make the irritation worse—it's like drinking spiced water, you can really feel your tonsils.
The pain isn't severe, but it's always there, making me constantly aware of the irritation. About a month ago, I had a really bad two-week episode of tonsil pain, but then it went away again.
I have a surgery appointment to get my tonsils removed, but I'm really unsure about it. The surgeon has tried to convince me not to go through with it, and I've already been to the hospital twice and canceled another two times. They've told me all sorts of scary things to make me want to avoid the surgery.
I'm conflicted. I could live with this mild ache and the thought that I'm too scared for the surgery. I could endure 2 to 4 weeks of intense pain a few times a year. But I'm scared of the surgery and I don't know if I should go through with it.
I'm not a severe case, but I've had several infections over the past three years, with the last one and a half years being particularly tough. It's gotten better, and I can live a somewhat normal life again. But this constant throat irritation, the feeling of my tonsils being irritated, and the low-level pain—I don't know if I should accept this for the rest of my life.
I'm really confused... 😭
Any advice or shared experiences would be greatly appreciated. Thank you!
2024.05.19 16:08 LJ1720 Adjuvant estrogen therapy when pCR to neoadjuvant chemo achieved?
Sorry that the title is confusing. I hope I can explain my question clearly enough.
I was diagnosed with a TNBC primary breast tumor and a ER+ lymph node at the end of October 2023. I finished the Keynote-522 regimen and had a pCR in both the breast and lymph node. Residual cancer burden is 0.0000000000000…
I will likely go on to have WBI and RNI, as well as continue with pembrolizumab (aka Keytruda). This is the current standard for TNBC regardless of pCR or not.
Adjuvant hormone therapy is the standard for hormone positive breast cancer, but I am wondering if it is really indicated in a pCR setting? My case is somewhat of a strange constellation and I am having trouble finding statistics on the matter. With triple positive that achieve pCR it is absolutely still indicated, but I am not so sure if that is because of the nature of triple positive (they also go on to continue their antibody therapy too).
I’m just wondering if anyone has come across a study regarding the efficacy of adjuvant hormone therapy (in my case, likely AI because of HER2 negative status) in patient who achieved pCR after NAC?
I hope this post is not jibberish!
Thanks in advance!
submitted by LJ1720 to breastcancer [link] [comments]
I was diagnosed with a TNBC primary breast tumor and a ER+ lymph node at the end of October 2023. I finished the Keynote-522 regimen and had a pCR in both the breast and lymph node. Residual cancer burden is 0.0000000000000…
I will likely go on to have WBI and RNI, as well as continue with pembrolizumab (aka Keytruda). This is the current standard for TNBC regardless of pCR or not.
Adjuvant hormone therapy is the standard for hormone positive breast cancer, but I am wondering if it is really indicated in a pCR setting? My case is somewhat of a strange constellation and I am having trouble finding statistics on the matter. With triple positive that achieve pCR it is absolutely still indicated, but I am not so sure if that is because of the nature of triple positive (they also go on to continue their antibody therapy too).
I’m just wondering if anyone has come across a study regarding the efficacy of adjuvant hormone therapy (in my case, likely AI because of HER2 negative status) in patient who achieved pCR after NAC?
I hope this post is not jibberish!
Thanks in advance!
2024.05.19 16:03 AdInteresting2502 Journey so far
In case it helps other newly diagnosed, this is my journey so far. 1 month ago ultrasound of new lump I had in left breast. Told I had invasive breast cancer. Then sent for mammogram where they found 3 dodgy lymph nodes on left side as well, along with another suspicious lump in right. Sent for biopsies on all the lumps (no one told me before these just how much they hurt or how sore you are after, I recommend taking someone with you). Cancer confirmed in left breast and 3 lymph nodes and oestrogen and progesterone positive, but HER2 negative. Right lump still undetermined. Met with surgeon and sent for PET scan to ascertain if spread. This 1 week wait whilst waiting for the results was the most god damn terrifying of my life!! Met with surgeon again, PET scan showed no obvious spread. 4 days later I had double mastectomy and what I thought was removal of 3 lymph nodes. Woke up and was told all 23 lymph nodes on my left side were cancerous and they also performed auxiliary lymph node clearance on left side. I am now 2 weeks post surgery, and I am not going to lie- recovery from it has proved both physically and emotionally tough. They put implants in same time as mastectomy. In 2 days I find out next stage of the treatment plan and apparently I will have to have radiation and chemo. I feel extremely lucky I caught it when I did, and cancer is such a sneaky farker, as she said she would not of gone down the cure path (surgery), but just the medically manage path is she knew it was in 23 lymph nodes (phew). I still have a long journey to go, but my big tips from what I have already been through - the time waiting for the test results is beyond terrible, and once you know what you are dealing with it will get better - if you have an option to not work, or take leave from work, defo do that (I would not be able to manage both myself) - take someone to your appointments with you - recovery from surgery is hard, so be kind with yourself - if you have lymph nodes removed, it is even more painful, but so important to exercise those arms whenever you can - I am on day 16 post surgery and I am getting better everyday. SO WILL YOU - be kind to yourself, cancer is a lot I got this, and so do you my sisters ❤️🩹❤️🩹❤️🩹❤️🩹❤️🩹
submitted by AdInteresting2502 to breastcancer [link] [comments]
2024.05.19 15:24 Loose_Phrase_9203 Worsening back pain after treatment?
I’ve had back pain before, and even had surgery to relieve it, but this is different. I’ve brought this up with my RO and my plain oncologist, but wanted to see if anyone here has experienced this. Next week I’ll be talking to my GP.
A reminder of my DX: Gleason 9, spread to local lymph nodes. Treated with 28 fractions of EBRT, finished mid-April.
Strangely, during my radiation treatment, despite having bouts of “back” pain leading up to it, I experienced no back pain during treatment, until the final week. Since then it’s been getting worse, waking me up at night and making it difficult to find a comfortable position sitting or lounging.
An additional data point; I’ve been taking Orgovyx since December, and have just stated taking Abiraterone a week ago.
I’d describe it as a burning feeling, sometimes centered on my left hip. Sometimes it feels like my kidneys. No visible blood in my urine or stool. No pain urinating. Urinating a lot since treatment and since starting Abiraterone.
Not really looking for medical diagnosis so much as wanting to know: has anyone else experienced this? It could just be back problems on top of this other nonsense, but as I say about it in my comic, “it just feels different.”
Thanks.
submitted by Loose_Phrase_9203 to ProstateCancer [link] [comments]
A reminder of my DX: Gleason 9, spread to local lymph nodes. Treated with 28 fractions of EBRT, finished mid-April.
Strangely, during my radiation treatment, despite having bouts of “back” pain leading up to it, I experienced no back pain during treatment, until the final week. Since then it’s been getting worse, waking me up at night and making it difficult to find a comfortable position sitting or lounging.
An additional data point; I’ve been taking Orgovyx since December, and have just stated taking Abiraterone a week ago.
I’d describe it as a burning feeling, sometimes centered on my left hip. Sometimes it feels like my kidneys. No visible blood in my urine or stool. No pain urinating. Urinating a lot since treatment and since starting Abiraterone.
Not really looking for medical diagnosis so much as wanting to know: has anyone else experienced this? It could just be back problems on top of this other nonsense, but as I say about it in my comic, “it just feels different.”
Thanks.
2024.05.19 15:10 Jlevanz After a year I finally have answers
submitted by Jlevanz to sarcoidosis [link] [comments]
2024.05.19 13:49 AnxiousDiva143 Just diagnosed
Hi everyone. I just got a call from the doctor that did my biopsy that I have invasive ductal carcinoma and the size measurements were less than a cm around and that the lymph nodes biopsied did not show any cancer. This was last week. I know maybe I’m overly anxious but when did you get your hormone and her2 status results after this? I see my pcp and set up an appt with a breast surgeon near the end of this week. Not knowing the plan is making me very anxious as is waiting around. I’m trying to stay positive and hoping for the best but I feel like no one has really explained much to me in terms of what comes next and what to expect. I am under 40 and have small kids. It’s hard for me to tell people because I just get this look of pity from people and it makes me feel even worse. I have been reading some of your stories I know everyone has different experiences. I am just hoping for the best. Thank you. You all are amazing people!
submitted by AnxiousDiva143 to breastcancer [link] [comments]
2024.05.19 13:24 Xikolo UPDATE, Blood tests, CRP etc.
 | So I had sore movable lymph nodes in my neck and groin, the rest of my results came back do these look alarming? tested negative for mono, but I believe it indicates I have a bacterial infection? I do have a g.i condition that correlates to Gastritis or some infection, now I do have elevated liver enzymes times due to pcos, so a weird test wouldn't be surprising. submitted by Xikolo to Anemic [link] [comments] https://preview.redd.it/fbi43xbdbd1d1.jpg?width=3720&format=pjpg&auto=webp&s=87555b7cb677edcc9247aa0036480e963e6a76cf https://preview.redd.it/ru5hntbdbd1d1.jpg?width=3793&format=pjpg&auto=webp&s=f463291b31d0dc0e82b6e8fdf171c30ed096f062 https://preview.redd.it/xniaitbdbd1d1.jpg?width=4000&format=pjpg&auto=webp&s=307f060ac51f1a288a1a1bf26a622af8af21bbe7 |
2024.05.19 12:30 Simpleladycs Erythema Nodosum as side effect
Unfortunately after 1 year of Pembro immunotherapy, my first scans after treatment showed cancer in lymph nodes. I had surgery on March 21 and I started Mekinist and Tafinlar meds (BRAF+) on May 13. First few days were ok, just some fatigue, but then the fever, vicious body shakes, chills and sweats started on May 16. Extra Strength Tylenol seems to be helping with the fevers, which I am taking every 4 hours or so. The part that I am having trouble dealing with is the large, angry, hot and very painful red welts that seem to have started appearing all my body, including the bottoms of my feet. They are so painful, it feels as though I have bruises all over my body. It hurts to walk and to sit on anything, sitting on a pillow or my bed is more tolerable.
I started noticing a few red bumps on my legs on May 16 but I didn’t really think anything of it. My skin has been really sensitive, so I thought it was just irritated. But then on May 17 I noticed more of them and I called my hospital cancer care clinic and spoke with a nurse. She said she has never heard of this side effect and to continue taking the meds and monitor over the weekend. It’s a long weekend here in Ontario, so I will call again on Tuesday.
Searching the internet, I found this may be Erythema Nodosum. Has anyone experienced this while taking Mekinist and Tafinlar? If so, can you share your experience?
submitted by Simpleladycs to melahomies [link] [comments]
I started noticing a few red bumps on my legs on May 16 but I didn’t really think anything of it. My skin has been really sensitive, so I thought it was just irritated. But then on May 17 I noticed more of them and I called my hospital cancer care clinic and spoke with a nurse. She said she has never heard of this side effect and to continue taking the meds and monitor over the weekend. It’s a long weekend here in Ontario, so I will call again on Tuesday.
Searching the internet, I found this may be Erythema Nodosum. Has anyone experienced this while taking Mekinist and Tafinlar? If so, can you share your experience?