Jcpenney coupons survey printable may 2011 Perioral dermatitis doxycycline

HardImages2 HARDNESS Scale

2024.05.19 08:22 blackhydroflask HardImages2 HARDNESS Scale

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2024.05.19 08:01 editorksqupl JCPenney Promo Code for May 2024

Visit this page for JCPenney Promo Code for May 2024. The website offers a wide selection of coupons, promo codes, and discount deals that are updated regularly, just visit the website to find the perfect one for you.
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2024.05.19 05:20 qwas12357 BPD and hurdles to recovery

Vital Environmental Factors That Can Prevent Recovery From BPD:
If, as a result of childhood trauma, we have developed post-traumatic stress disorder (PTSD) or borderline personality disorder (BPD) our post-traumatic environment can have an extremely strong impact upon our chances of recovery. I list some particularly important factors below :
LACK OF SUPPORT FROM FRIENDS, FAMILY AND THE WIDER COMMUNITY / SOCIETY
If we are not provided with such support, but, instead, are shunned and ignored, it is highly likely that our feelings of worthlessness, vulnerability and isolation will be intensified.
Support needs to be non-judgmental, empathic and validating both of our emotional pain and also of our interpretation of how our adverse experiences have affected us.
Also, those providing the support need to be 'emotionally literate' (i.e. able and willing to discuss feelings and emotions in a compassionate and understanding manner)
NOT BEING BELIEVED
Obviously, if people we talk to about our traumatic experiences don't believe what we are saying or believe we are exaggerating the seriousness of what happened to us (or the seriousness of the effect it has had upon us) our psychological condition is likely to be severely aggravated: our lack of self-esteem, sense of despair, sense of worthlessness, sense of unlovability, feelings of isolation and any feelings of anger, bitterness and resentment we may have are all likely to be severely intensified.
SECONDARY VICTIMIZATION
We need to avoid those who would cause us secondary victimization. Secondary victimization occurs when those who ought to be helping us instead harm us further. Indeed, the example of not being believed (see above) is one such form of secondary victimization.
Other examples of secondary victimization include :
On top of these problems, it can, too, be difficult to get professional support:
A recent study carried out by Proctor et al., 2020, has produced further evidence that BPD sufferers frequently find it highly problematic gaining access to effective treatment such as dialectical behaviour therapy, or DBT. (In relation to this problem, you may wish to read my previously published articles: How Malignant Alienation May Impoverish Care BPD Patients Receive.)
Whilst many professional used to believe BPD was typically unresponsive to treatment, this can no longer operate as a feasible excuse as there now exists an increasingly large and growing body of evidence that a substantial proportion of those who have been diagnosed with this extremely serious condition (which is closely linked to severe and protracted, interpersonal, childhood trauma) can be treated effectively, at least to the degree that they no longer fulfil the requisite criteria necessary for the diagnosis of BPD to continue to be applicable.
The authors of the study suggest that difficulty obtaining proper treatment is linked to the continued stigma attaching itself to a BPD diagnosis. However, as sufferers of the condition become increasingly knowledgeable about the illness and of the existence of evidence base therapies like DBT (see above), so too should their confidence assertively to request the opportunity to access such treatment. After all, about one in ten BPD sufferers eventually die by suicide, so the need for such individuals to be offered compassionate, non-judgmental, empathetic and non-discriminatory treatment can hardly be overstated. The treatment of extreme mental pain is just as much of an ethical imperative as is the treatment of extreme physical pain.
The Australian study surveyed 500 patients between 2011 and 2017 and found that those offered appropriate help often waited between a year and a year-and-a-half to receive it. The author of the study pointed out that this not only resulted in unnecessary suffering for the BPD sufferer but also placed extra strain on hospital emergency services (i.e. due to more BPD sufferers reaching crisis point, attempting suicide, self-medicating with dangerous levels of alcohol and/or narcotics, extreme self-harm such as self-cutting and self-burning etc.).
The researchers concluded by emphasizing the importance of health professionals applying NHMRC BPD guidelines in order to support front line services responsible for the welfare of BPD sufferers.

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2024.05.19 04:55 1ndonlylis White papules on center of cheek

White papules on center of cheek
I've been dealing with this cluster of whiteheads for probably 1 1/2 years now. It's literally only in one area of my face (middle of left cheek). The weird part about it is I'II wake up and there will be no whiteheads, then by the middle of the day there are 4-5. The doc diagnosed it as perioral dermatitis & rosacea It varies so much on a day to day basis. I've worked directly with a dermatologist and there's no resolve. Some of the oral medications I've tried are: doxycycline (twice), spironolactone, and ivermectin. Some of the face washes I've tried are: sulfur face wash, dove unscented soap, panoxyl, ketoconazole, and cerave. Some of the topicals I've used are mupirocin, bactrim, cephalexin, and a Azelaic/ ivermectin/metronidazole 15/1/1% cream. I'm at a loss. Some of the treatments will help, but then it'll come right back in a couple days Has anyone experienced this? I’m willing to try anything at this point
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2024.05.19 02:45 The_Brand94 RIGL Thesis 5/18/2024

~RIGL Thesis – 5/18/2024~
Outstanding Shares 175M
131 Institutional Holders
111,129,461 Total Shares Held
63.36% Institutional Ownership
Total Cash on Hand 3/31/2024 = $49.6M
Total Debt: $101.5M
Cash Burn Approximate = $8M per quarter (6 quarters of cash without any increases in revenue)
Q12023 REV = $26M
Q22023 REV = $26.8M
Q32023 REV = $28.1M
Q42023 REV = $35.8M
Q12024 REV = $29.5M (Decline from Q4 likely from end of year versus new-year tracking of Rx and shipments of drugs, resetting of Copays)
Most Recent EPS -$0.05 per share
May 22, 2024 - Vote on S will take place, caution
~Statistics Applicable To Thesis~
333.3 million US Population (2022)
8,109,679,892 Global Population (2024)
~Drugs On Market~
~Tavalisse – Treatment for ITP, FDA Approved April 17, 2018~
~What is ITP?~
Immune thrombocytopenia (ITP) is an illness that can lead to bruising and bleeding. Low levels of the cells that help blood clot, also known as platelets, most often cause the bleeding.
Once known as idiopathic thrombocytopenic purpura, ITP can cause purple bruises. It also can cause tiny reddish-purple dots on the skin that look like a rash.
Children can get ITP after a virus. They most often get better without treatment. In adults, the illness often lasts months or years. People with ITP who aren't bleeding and whose platelet count isn't too low might not need treatment. For worse symptoms, treatment might include medicines to raise platelet count or surgery to remove the spleen. Immune thrombocytopenia (ITP) - Symptoms and causes - Mayo Clinic
~What is Tavalisse?~
TAVALISSE is a prescription medication used to treat adults with low platelet counts due to chronic immune thrombocytopenia (ITP) when a prior treatment for ITP has not worked well enough. It is not known if TAVALISSE is safe and effective in children.
The cost for Tavalisse oral tablet 100 mg is around $15,404 for a supply of 60 tablets, depending on the pharmacy you visit. Quoted prices are for cash-paying customers and are not valid with insurance plans. This price guide is based on using the Drugs.com discount card which is accepted at most U.S. pharmacies.
Tavalisse Prices, Coupons, Copay & Patient Assistance - Drugs.com
TAVALISSE IS AN ORAL MEDICATION TAKEN TWICE DAILY WITH OR WITHOUT FOOD1
A 12-week evaluation period is recommended
60 tablets = 1 month supply, evaluation period = 3 months, Cost for 3 months = $46,212 Cash, assuming cheaper through wholesale, insurance, discount cards, etc.
Dosing TAVALISSE® (fostamatinib disodium hexahydrate) tablets (tavalissehcp.com)
~Addressable Market~
“Our findings suggest that nearly 20,000 children and adults are newly diagnosed with ITP each year in the US, substantially higher than previously reported. Among patients requiring formal medical care, the economic burden during the first 12 months following diagnosis is high, with estimated US expenditures totaling over $400 million.”
Primary immune thrombocytopenia in US clinical practice: incidence and healthcare burden in first 12 months following diagnosis - PubMed (nih.gov)
The estimated prevalence of ITP in the United States is 9.5 per 100,000 people, with a global prevalence of over 200,000 people at any given time [1].
Immune thrombocytopenia. [ Oct; 2022 ]. 2022. https://rarediseases.org/rare-diseases/immune-thrombocytopenia
~Author Calculations/Estimates~
ITP estimated cases based on measured statistics 31,635 cases a year in the US and 770,355 cases globally each year.
~Rezlidhia – R Acute Myeloid Leukemia, FDA Approved December, 22, 2022~
~What is Relapsed or Refractory Acute Myeloid Leukemia?~
Relapsed, or recurrent, acute myeloid leukemia (AML) means the leukemia has come back after treatment and remission.
Refractory AML means the leukemia did not respond to treatment. Complete remission has not been reached because the chemotherapy drugs did not kill enough leukemia cells.
Both relapsed and refractory AML need more treatment to reach complete remission.
Your healthcare team will suggest treatments based on your needs and work with you to develop a treatment plan. Some factors considered for your treatment include:
your age
your health
how long the leukemia was in remission
treatments you had before
where the leukemia comes back
Treatment options usually include chemotherapy and a stem cell transplant if possible. Targeted therapy may also be used.
Treatments for relapsed or refractory acute myeloid leukemia Canadian Cancer Society
~What is IDH1?~
Somatic mutations in isocitrate dehydrogenase (IDH) genes occur frequently in adult Acute myeloid leukemia (AML) and less commonly in pediatric AML… Enhanced genomic and epigenomic profiling of acute myeloid leukemia (AML) has led to identification of recurrent mutations that are prognostic and are candidates for targeted therapy. Somatic mutations in isocitrate dehydrogenase (IDH) genes, IDH1 and IDH2, occur in ∼6% to 16% and ∼8% to 19% of adult patients with AML, respectively.1-5 In pediatric AML, IDH mutations are rare, occurring in <4% of patients.6-11
Characteristics and prognostic impact of IDH mutations in AML: a COG, SWOG, and ECOG analysis Blood Advances American Society of Hematology (ashpublications.org)
~What is Rezlidhia?~
REZLIDHIA is a prescription medicine used to treat adults with acute myeloid leukemia (AML) with an isocitrate dehydrogenase-1 (IDH1) mutation when the disease has come back or has not improved after previous treatment(s).
Targeted Treatment REZLIDHIA® (olutasidenib) capsules
The cost for Rezlidhia oral capsule 150 mg is around $17,468 for a supply of 30 capsules, depending on the pharmacy you visit. Quoted prices are for cash-paying customers and are not valid with insurance plans. This price guide is based on using the Drugs.com discount card which is accepted at most U.S. pharmacies.
Rezlidhia Prices, Coupons, Copay & Patient Assistance - Drugs.com%20is%20a%20member,on%20the%20pharmacy%20you%20visit.)
~Addressable Market~
The annual incidence of new cases in both men and women is approximately 4.3 per 100,000 population, totaling over 20,000 cases per year in the United States alone.[13] The median age at the time of diagnosis is about 68, with a higher prevalence observed among non-Hispanic Whites. Furthermore, males exhibit a higher incidence compared to females, with a ratio of 5:3.
Acute Myeloid Leukemia - StatPearls - NCBI Bookshelf (nih.gov)
~Author Calculations/Estimates~
Cases of AML with IDH1 would be 11% based on the median of statistics above (6% to 16%) leaving approximately 1500 to 2000 cases a year in the US. Appling the same calculations to world population would amount to approximately 38,500 cases a year globally.
~Gavreto – Treats RET+ Non-Small Cell Lung Cancer In Adults and RET+ Thyroid Cancer in Kids and Adults, FDA Approved August 9, 2023~
For the sake of common ground, I am going to assume these types of cancers do not need to be elaborated on as we all likely have a basic understanding of what they are. The medical conditions treated by Tavalisse and Rezlidhia I felt needed a more in-depth explanation because they are not common. I will elaborate on RET+ a little later in this writing.
~What is Gavreto?~
GAVRETO is an oral once daily prescription medicine used to treat certain cancers caused by abnormal rearranged during transfection ~(RET+)~ genes in:
Adults with non-small cell lung cancer (NSCLC) that has spread
Adults and children 12 years of age and older with advanced thyroid cancer or thyroid cancer that has spread who require a medicine by mouth or injection (systemic therapy) and who have received radioactive iodine and it did not work or is no longer working*
It is not known if GAVRETO is safe and effective when used to treat cancers caused by abnormal RET genes in children for the treatment of NSCLC or in children younger than 12 years of age for the treatment of thyroid cancer.
Home GAVRETO® (pralsetinib)
The cost for Gavreto oral capsule 100 mg is around $11,745 for a supply of 60 capsules, depending on the pharmacy you visit. Quoted prices are for cash-paying customers and are not valid with insurance plans. This price guide is based on using the Drugs.com discount card which is accepted at most U.S. pharmacies.
The recommended dosage for adults and children 12 and over is 400mg orally once daily. Each capsule is 100mg, which means you will take 4 capsules. Gavreto should be taken on an empty stomach, at least 1 hour before or 2 hours after a meal.
Gavreto Prices, Coupons, Copay & Patient Assistance - Drugs.com
~What is Rearranged During Transfection Positive (RET+)?~
RET-positive cancer is caused by a mutation or abnormal re-arrangement of the RET gene. It occurs most commonly in lung cancer and several types of inherited and sporadic thyroid cancers. RET alterations also occur in an estimated 1-2% of multiple other cancers, including ovarian, pancreatic, salivary, breast, and colorectal cancers.
RETpositive Empowering Patients and Driving Research
Rearranged during transfection (RET) rearrangements were first identified as oncogenic drivers in NSCLC in 2012. The proportion of patients with NSCLC who have RET rearrangements (ie, fusion-positive disease) is approximately 1%-2%.
RET Fusion-Positive Non-small Cell Lung Cancer: The Evolving Treatment Landscape The Oncologist Oxford Academic (oup.com)
RET alterations occur most commonly in lung cancer (non-small cell lung cancer (NSCLC)) and the number of new cases diagnosed each year is considerable, accounting for approximately 37,500 [IG1] cases worldwide and 4,000 cases in the US (2% of NSCLC) (2,3). RET alterations are also common in several types of inherited and sporadic thyroid cancers and can occur in other types of cancers like ovarian, breast, pancreatic, and colorectal cancers, among others (4-8) adding >110,000 cases yearly worldwide (9).
What is RET Positive Lung Cancer? - The Happy Lungs Project
(2) Although medullary thyroid carcinoma represents 5-10% of all thyroid cancers, activating RET gene abnormalities occur in over 90% of hereditary and approximately 40%-60% of sporadic medullary thyroid carcinoma cases.
Patients – RETpositive%20Although%20medullary%20thyroid%20carcinoma,sporadic%20medullary%20thyroid%20carcinoma%20cases.)
~Prevalence of Non-Small Cell Lung Cancer~
Most lung cancer statistics include both small cell lung cancer (SCLC) and non-small cell lung cancer (NSCLC). In general, about 10% to 15% of all lung cancers are SCLC, and about 80% to 85% are NSCLC.
Lung cancer (both small cell and non-small cell) is the second most common cancer in both men and women in the United States (not counting skin cancer). In men, prostate cancer is more common, while breast cancer is more common in women.
The American Cancer Society’s estimates for lung cancer in the US for 2024 are:
About 234,580 new cases of lung cancer (116,310 in men and 118,270 in women)
About 125,070 deaths from lung cancer (65,790 in men and 59,280 in women)
Lung Cancer Statistics How Common is Lung Cancer? American Cancer Society
Worldwide, an estimated 2,206,771 people were diagnosed with lung cancer in 2020. These statistics include both small cell lung cancer and NSCLC.
Lung Cancer - Non-Small Cell: Statistics Cancer.Net
~Author Calculations/Estimates~
Approximately 187,664 cases of NSCLC in the US based on an 80% factor.
Approximately 1,765,416 cases of NSCLC worldwide based on an 80% factor.
~Prevalence of Thyroid Cancer~
Rate of New Cases and Deaths per 100,000: The rate of new cases of thyroid cancer was 13.5 per 100,000 men and women per year. The death rate was 0.5 per 100,000 men and women per year. These rates are age-adjusted and based on 2017–2021 cases and 2018–2022 deaths.
Lifetime Risk of Developing Cancer: Approximately 1.2 percent of men and women will be diagnosed with thyroid cancer at some point during their lifetime, based on 2017–2019 data. Lifetime risk based on data through 2022 will available soon.
Prevalence of This Cancer: In 2021, there were an estimated 979,295 people living with thyroid cancer in the United States.
Thyroid Cancer — Cancer Stat Facts
About 44,020 new cases of thyroid cancer (12,500 in men and 31,520 in women)
About 2,170 deaths from thyroid cancer (990 in men and 1,180 in women)
Thyroid cancer is often diagnosed at a younger age than most other adult cancers. The average age when a person is diagnosed with thyroid cancer is 51.
This cancer is about 3 times more common in women than in men. It is about 40% to 50% less common in Black people than in any other racial or ethnic group.
Key Statistics for Thyroid Cancer American Cancer Society)
Addressable Market
Given Gavreto’s dual treatment capacity, the total amount of potential patients with NSCLC with RET+ indications would be approximately 2,800 cases in the US and approximately 26,500 cases worldwide each year using a factor of 1.5% of total NSCLC cases. The total amount of treatable cases for Thyroid Cancer would be approximately 650 in the US and 16,500 cases worldwide respectively each year applying the same 1.5% RET+ percentage rate. DOUBLE CHECK MATH…
~Rigel Pharmaceuticals Pipeline~
~IRAK/4 – Clinical Trials~
Rigel’s investigational candidate, R289, is an oral, potent and selective inhibitor of interleukin receptor-associated kinases 1 and 4 (IRAK1/4).
Toll like receptors (TLRs) and the interleukin 1 receptor family (IL-1Rs) play a critical role in the innate immune response and dysregulation of these pathways can lead to a variety of inflammatory conditions such as psoriasis, rheumatoid arthritis, and inflammatory bowel disease. Chronic stimulation of both receptor systems has also been implicated in causing a pro-inflammatory bone marrow environment leading to persistent cytopenias in lower-risk myelodysplastic syndrome (LR-MDS) patients1.
R835 is a selective dual inhibitor of IRAK1/4 that blocks TLR4 and IL-1R-dependent systemic cytokine release. In preclinical studies, R835 demonstrated activity in multiple animal models of inflammatory disease2,3 and showed that dual inhibition of IRAK1 and IRAK4 provided more complete suppression of inflammatory cytokines when compared to an IRAK4-selective inhibitor4.
Development of R289:
In a Phase 1 clinical trial, R835 was well tolerated and inhibited LPS-induced inflammatory cytokine production in healthy volunteers, demonstrating proof-of-mechanism.5 Phase 1 clinical studies of R289 (an oral prodrug that is rapidly converted to R835 in the gut) are also complete.
A Phase 1b open-label, multicenter trial of R289 in patients with relapsed/refractory lower-risk MDS is currently enrolling (NCT05308264). The primary endpoint for this trial is safety with key secondary endpoints including preliminary efficacy and evaluation of pharmacokinetic properties.
~Bemcentinib – Bergenbio Partnership~
In June 2011, Rigel entered into an exclusive, worldwide research, development and commercialization agreement with BerGenBio for its investigational AXL receptor tyrosine kinase (AXL) inhibitor, R428 (now referred to as bemcentinib).
Bemcentinib is a potent, selective and orally bioavailable AXL inhibitor and the furthest along in clinical trials. In preclinical studies, bemcentinib was shown to have an effect as a single agent therapeutic in the prevention and reversal of acquired resistance to standard of care cytotoxics and targeted therapies and may also slow or prevent tumor metastasis.
Rigel received an upfront payment and is eligible for milestone payments and potential sublicensing revenue, as well as tiered royalty payments on any future net sales of products emerging from the collaboration.
~R552 Systemic – Eli Lilly Partnership~
Rigel’s investigational candidates are oral, potent and selective inhibitors of receptor-interacting serine/threonine-protein kinase 1 (RIPK1).
RIPK1 is a critical signaling protein implicated in a broad range of key inflammatory cellular processes including necroptosis, a type of regulated cell death, and cytokine production. In necroptosis, cells rupture leading to the dispersion of cell contents, which can trigger an immune response and enhance inflammation. RIPK1 inhibition has therapeutic potential in treating autoimmune, inflammatory, and neurodegenerative disorders.
Rigel’s RIPK1 inhibitor program includes R552, a systemic molecule being developed for the treatment of autoimmune and inflammatory disorders, and brain penetrating RIPK1 inhibitors for central nervous system (CNS) diseases. In preclinical studies, R552 demonstrated prevention of joint and skin inflammation in a RIPK1-mediated murine model of inflammation and tissue damage.
Development of R552:
In Q2 2023, the initial Phase 2a trial (NCT05848258) in moderately to severely active rheumatoid arthritis (RA) was initiated by partner Eli Lilly.
Development CNS-penetrating RIPK1 inhibitors:
Currently in preclinical studies.
~Milademetan – Daiichi Sankyo Partnership~
Rigel has a long-standing collaboration with Daiichi-Sankyo for developing murine double minute 2 (MDM2) protein inhibitors in cancer, which were discovered in Rigel’s laboratories.
Preliminary safety and efficacy data from an early Phase 1 study of milademetan (formerly DS-3032), an oral selective MDM2 inhibitor, in hematological malignancies suggests that it may be a promising potential treatment for oncology indications.
Rigel received an upfront payment and is eligible for milestone payments, as well as tiered royalty payments on any future net sales of any products emerging from the collaboration.
~Rxxx (CNS Penetrant) – Eli Lilly Partnership~
Rigel’s investigational candidates are oral, potent and selective inhibitors of receptor-interacting serine/threonine-protein kinase 1 (RIPK1).
RIPK1 is a critical signaling protein implicated in a broad range of key inflammatory cellular processes including necroptosis, a type of regulated cell death, and cytokine production. In necroptosis, cells rupture leading to the dispersion of cell contents, which can trigger an immune response and enhance inflammation. RIPK1 inhibition has therapeutic potential in treating autoimmune, inflammatory, and neurodegenerative disorders.
Rigel’s RIPK1 inhibitor program includes R552, a systemic molecule being developed for the treatment of autoimmune and inflammatory disorders, and brain penetrating RIPK1 inhibitors for central nervous system (CNS) diseases. In preclinical studies, R552 demonstrated prevention of joint and skin inflammation in a RIPK1-mediated murine model of inflammation and tissue damage.
Development of R552:
In Q2 2023, the initial Phase 2a trial (NCT05848258) in moderately to severely active rheumatoid arthritis (RA) was initiated by partner Eli Lilly.
Development CNS-penetrating RIPK1 inhibitors:
Currently in preclinical studies. Pipeline :: Rigel Pharmaceuticals, Inc. (RIGL)
~Summary and Prediction~
The current share price of sub $1 does not feel justified. I would anticipate financial breakeven by the end of 2024 or potentially in Q1 or Q2 of 2025. The robust pipeline, progress, and expected revenue growth are enough to justify a much higher valuation. The debt load is manageable, but the potential for S is concerning. I believe that the S is not necessary and revenue growth and progress should speak for itself. I am not as bullish as the analysts at HC Wainright for a $15 PT, but the valuation should be at least 3x to 5x from the current value. This thesis does not highlight the patents surrounding their drugs either which some extend into 2035 and beyond. Perhaps what Wall Street is discounting is the fact that most of the drugs are very niche. However, the currently available drugs have an addressable market, albeit less universal than some, but you should value it in the sense of multiple facets (a 1000 headed snake is the phrase I wanted to use). I believe the company should be valued with specialty drugs in mind which would command a higher PE ratio. At the current day and time of writing, the value should be at least $1.50 to $1.75 ~at a minimum~ with a 12 month price target of $3 to $5+. I will be looking for continued revenue growth in each quarter this year and realization of revenue from Gavreto in Q2 or Q3 this year. The partnerships should not be discounted either and the current share price if it lingers here perhaps may attract a merger or acquisition. I initially began the research thinking that perhaps the drugs were too niche, but given the multiple drugs they are working with, I believe their revenue sources will continue to grow if you do not focus on one particular drug as the main performer. With the most recent inflation report being cooler than expected, I would suspect larger funds and institutions will be circling back to riskier assets.
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2024.05.18 23:31 Tesa_Tesanovic1988 Venture Capital and Innovation Strategies

Innovation is the lifeblood of business growth and development. Without it, your organization will fall behind its competition and eventually die out. However, innovation is expensive, and many small and medium-sized organizations can’t afford to innovate unless they get financial help from external sources.

Investments in bio-engineering can be risky, as many startups and early-stage companies may face regulatory hurdles, intellectual property challenges, or other barriers to success. However, for investors with a long-term outlook and a strong appetite for innovation, bio-engineering can offer significant opportunities for growth and returns.
Venture capital is one of the most common sources of financing for organizations that want to invest in innovation. Venture capital is a type of dedicated financial help that funds businesses to make a capital gain until publicizing them or even selling them outright. A distinguishing feature of venture capital involves screening, monitoring, and advising on a portfolio of its businesses. These non-financial services enable venture capitalists to choose businesses with high growth potential and make them succeed. The three distinctive features discussed before add to the venture capital’s edge over other types of financing that are not as dedicated (Sorensen, 2007).
Venture capitalists normally select companies that they can exit fast enough. This means that they select innovative organizations whose ROI is expectedly high. Therefore, such organizations are those that use knowledge to generate innovative capabilities to create profit in the short term.
Innovation is a process of continuous improvement and growth. It leads to the creation of new value or business ideas, which in turn contributes to the growth of any organization. The ability to innovate helps in increasing the revenue and profit margins of an organization by making it competitive in its industry.
Venture capitalists are interested in investing in innovative startups because they believe this will help them achieve their financial goals faster compared to the companies that do not invest in innovation. Venture capitalists want their investment to grow fast so they can exit quickly after making their money back at a higher rate than what they invested initially into it.
In the age of the knowledge economy, innovation is a main source of competitiveness (Daghfous, 2004). Based on what is known as the knowledge-based vision, the performance of the organization lies in its capacity to create, blend, recombine, and make use of knowledge (Grant, 1996). Therefore unstated, knowledge is indispensable to the capacity of an organization to innovate and favorably compete with others, causing it to be a strategic resource (Ibarra-Cisneros et al., 2021). The knowledge inside a firm is normally formed internally or by the outward acquisition of information and know-how. Accordingly, the knowledge absorptive capacity (AC) of a firm is vital for the creation of value inside a firm (Xie et al., 2018).
According to Davenport and Prusak (1998), knowledge cannot be completely dispersed without the backing of absorptive capacity. At the same time, the transfer of knowledge within a firm will come up as a main hindrance without the backing of absorptive capacity, inserting value on the significance of absorptive capacity within firms (Wuryaningrat, 2013).
Absorptive capacity has been described as the capacity of an organization to acknowledge the value of fresh outward information, integrate it, and implement it for business goals. Besides, it has become amongst the most dominant research scopes in business management. Huang et al. (2015) also note that absorptive capacity refers to a group of organizational practices that need to recognize and use knowledge, stressing the significance of absorptive capacity in the process of managing knowledge.
Most studies back the idea of absorptive capacity directly or indirectly prompting innovation and organizational financial outcomes (Tseng et al., 2011). The procedures of absorption of outward knowledge have grown into key aspects for innovation in organizations, making them to better adjust to transformations within the competitive atmosphere. Because of this, there are still many opportunities for research within the scopes of relational learning, absorptive capacity, as well as the attainment of a competitive edge (Tseng et al., 2011).
According to Xie et al. (2018), two vital gaps restrict deep hypothetical and empirical progresses in the management of absorptive capacity. Foremost, some programs of research have considered diverse proportions of absorptive capacity, while this dimensional separation of the construct and its function is not clear, conceptually and practically. Nonetheless, some studies have concentrated on the relationship between the diverse measures of absorptive capability and the innovation performance of a firm (Yaseen, 2020). Absorptive capacity is a tacit and intricate concept, making it challenging to measure. Learning the connection between venture financing and absorptive capacity can hence enhance our comprehension concerning how the source of financing impacts the innovation tactic of entrepreneurial organizations.

Absorptive Capacity and Innovation

Companies are working within a very competitive setting and need great measures of knowledge, which has turned into one of their most vital resources (Lian and Wu, 2010). To compete favorably, organizations cannot depend only on their external knowledge web but must progress their absorptive capacities to dynamically source new knowledge (Sancho-Zamora et al., 2021). This imposes methods that enable learning, allowing them to disperse and use the knowledge that will offer them fresh organizational innovations. Furthermore, the merging of this acquired knowledge is decided by an organization’s absorptive capacity. Hence, firms are required to possess and create, internal absorptive capacity to enhance innovation performance. This is vital since this form of capacity can impact the efficiency of innovation actions.
The first parties to describe absorptive capacity as the ability of an organization to assess fresh knowledge from outside, integrate it, and use it for commercial reasons were Cohen and Levingthal in 1990 (Wuryaningrat, 2013). A firm can obtain and efficiently utilize external and internal knowledge that will impact its innovation. This style looks at absorptive capacity as an outcome of not just research and development activities but similarly the variety or depth of the knowledge base of an organization, its former learning encounter, a mutual language, the presence of cross-functional points, and the mental frameworks, as well as problem-solving capability of the members in an organization (Camison and Fores, 2010). In this manner, absorptive capacity is vital for organizations to utilize outward knowledge and hence trigger inner innovation (Dutse, 2013).
Knowledge has become the most vital resource for organizations; outward knowledge concerning markets and technologies is thought to be key for generating inner knowledge in research and development units. Using absorptive capacity, organizations can change outward knowledge into innovative capabilities. Originally, absorptive capacity begins with gaining knowledge from the environment and it culminates by getting the best out of it (Saebi and Foss, 2015). This dynamic ability enables organizations to be in a better place to grow any form of innovation. Organizational learning theory recommends that an organization’s innovation actions are an outcome of its knowledge base.
Earlier research discovered that organizations having a greater absorptive capacity were more predisposed to undertake product, process, organizational, or even marketing innovations. In the same way, Calero-Medina and Noyons (2008) mapped programs of research connected to absorptive capacity and its connection to diverse domains, identifying substantial relations between absorptive capacity and innovation within the organization.
More current work, like the one by Chen and Chang (2012) discovered that the more the level of absorptive capacity of the organization, the more the level of innovativeness within the organization. They also discovered within their systematized literature review that most prevailing research concerning innovation literature accentuates the capacity to use outward knowledge. Moreover, this relation with fresh external knowledge enhances the absorptive capacity.
According to a research program undertaken by Liao et al (2007), empirical proof was given that innovation stems from the necessity for sharing knowledge, instigated by its absorptive capacity. When absorptive capacity progresses, it becomes very simple for anyone to form a noteworthy innovation grounded on acquired knowledge. Indarti (2010) similarly notes that absorptive capacity can be observed as a procedure by which a certain entity establishes innovative business goals (Wuryaningrat, 2013).
Notwithstanding the proof connecting absorptive capacity to innovation, this notion has developed in due course. The most comprehensive reconceptualization was suggested by Indarti (2010). They connected the idea to a set of company-wide routines and strategic procedures by which organizations acquire, change, and utilize knowledge to establish an active organizational capacity.

Dimensions of Innovation Capacity

Innovation is a vital element of the research enterprise, is very developed, and exists in all business procedures (Alshanty and Emeagwali, 2019). Nonetheless, the function of innovations, a main driver concerning a venture’s performance, has transformed in the latest years because of globalization and improved foreign competition (Pustorvrh et al., 2017). As a result, we comprehend innovation as the capacity of a firm to use knowledge and create novel products, services, and processes. Nonetheless, innovation typically encompasses some level of risk, which explains why outcomes are not always satisfying.
Various studies have demonstrated that innovativeness allows organizations to attain results, for instance, enhancement of the organization’s performance; growing exports; making a competitive edge; and or adding to the growth of the business. Generally, innovation assists organizations to react to competitive difficulties in globalized settings.
Innovativeness is an intricate capacity through which fresh knowledge and ideas are constantly used to attain excellent business performance using the integration of new offertories, product innovation, and the development of new processes for creating and distributing those novel offerings, and process innovation. These improve or sustain their efficiency and competitiveness. Process innovation concentrates on enhancing the efficiency and inner operations of an organization’s procedures to produce, bring together, or deliver the product. In this manner, another process can lessen the expenses or bring about extra production ability for an organization. Product innovation, conversely, is where an organization can present improved, distinguished, or even new products to the market to satisfy the needs of the consumers. Product innovation concentrates on the market and depends on robust abilities like quality, efficiency, speed, and flexibility, whereas process innovation has its place within the space of technical innovation. Both forms of innovation are closely connected and make up intricate procedures that normally encompass all functional sections of the organization.

References

Alshanty, A. M., and Emeagwali, O. L. (2019). Market-sensing capability, knowledge creation and innovation: the moderating role of entrepreneurial-orientation. J. Innov. Knowl. 4, 171–178. doi: 10.1016/j.jik.2019.02.002
Calero-Medina, C., and Noyons, E. C. (2008). Combining mapping and citation network analysis for a better understanding of the scientific development: the case of the absorptive capacity field. J. Informetr. 2, 272–279. doi: 10.1016/j.joi.2008.09.005
Camisón, C., and Forés, B. (2010). Knowledge absorptive capacity: new insights for its conceptualization and measurement. J. Bus. Res. 63, 707–715. doi: 10.1016/j.jbusres.2009.04.022
Chen, S. T., and Chang, B. G. (2012). The effects of absorptive capacity and decision speed on organizational innovation: a study of organizational structure as an antecedent variable. Contemp. Manag. Res. 8:7996. doi: 10.7903/cmr.7996
Daghfous, A. (2004). Absorptive capacity and the implementation of knowledge-intensive best practices. S.A.M. Adv. Manag. J. 69, 21–27.
Davenport, T. H., and Prusak, L. (1998). Working Knowledge: How Organizations Manage What They Know. Boston, MA: Harvard Business School Press.
Dutse, A. Y. (2013). Linking absorptive capacity with innovative capabilities: a survey of manufacturing firms in Nigeria. Int. J. Technol. Manag. 12, 167–183. doi: 10.1386/tmsd.12.2.167_1
Grant, R. M. (1996). Toward a knowledge based theory of frim. Strategic Management Journal, 17, 109–122. https://doi.org/10.2307/2486994
Huang, K. F., Lin, K. H., Wu, L. Y., and Yu, P. H. (2015). Absorptive capacity and autonomous R&D climate roles in firm innovation. J. Bus. Res. 68, 87–94. doi: 10.1016/j.jbusres.2014.05.002
Ibarra-Cisneros, M., Demuner-Flores, M. R., and Hernández-Perlines, F. (2021). Strategic orientations, firm performance, and the moderating effect of absorptive capacity. J. Strateg. Manag. doi: 10.1108/JSMA-05-2020-0121, [Epub ahead of print].
Indarti, N. (2010). The Effect of Knowledge Stickiness and Interaction on Absorptive Capacity. Groningen, The Netherlands: University of Groningen.
Liao, S. H., and Wu, C. C. (2010). System perspective of knowledge management, organizational learning, and organizational innovation. Expert Syst. Appl. 37, 1096–1103. doi: 10.1016/j.eswa.2009.06.109
Pustovrh, A., Jaklič, M., Martin, S. A., and Rašković, M. (2017). Antecedents and determinants of high-tech SMEs’ commercialisation enablers: opening the black box of open innovation practices. Econ. Res. 30, 1033–1056. doi: 10.1080/1331677X.2017.1305795
Saebi, T., and Foss, N. J. (2015). Business model for open innovation: matching heterogeneous open innovation strategies with business model dimensions. Eur. Manag. J. 33, 201–213. doi: 10.1016/j.emj.2014.11.002
Sancho-Zamora, R., Peña-García, I., Gutiérrez-Broncano, S., and Hernández-Perlines, F. (2021). Moderating effect of proactivity on firm absorptive capacity and performance: empirical evidence from Spanish firms. Mathematics 9:2099. doi: 10.3390/math9172099
Sørensen, Morten (2007) ‘How Smart is Smart Money: An Empirical Two-Sided Matching Model of Venture Capital,’ Journal of Finance, 62 (6), 2725–2762.
Tseng, C. Y., Chang Pai, D., and Hung, C. H. (2011). Knowledge absorptive capacity and innovation performance in KIBS. J. Knowl. Manag. 15, 971–983. doi: 10.1108/13673271111179316
Wuryaningrat, N. F. (2013). Knowledge sharing, absorptive capacity and innovation capabilities: an empirical study on small and medium enterprises in North Sulawesi. Indonesia. Gadjah Mada Int. J. Bus. 15, 61–77. doi: 10.22146/gamaijb.5402
Xie, X., Zoub, H., and Quick, G. (2018). Knowledge absorptive capacity and innovation performance in high-tech companies: a multi-mediating analysis. J. Bus. Res. 88, 289–297. doi: 10.1016/j.jbusres.2018.01.019
Yaseen, S. G. (2020). “Potential absorptive capacity, realized absorptive capacity and innovation performance,” in International Conference on Human Interaction and Emerging Technologies 2019, AISC 1018. ed. Ahram (Cham: Springer), 863–870.
Authors

Emilija Vukovic

Business Architecture Practice

Paul Lalovich

Organizational Effectiveness and Strategy Execution Practice
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2024.05.18 23:28 FakeElectionMaker What if a national conservative and economically populist Greek businessmen existed and became Prime Minister in 2012, only to compromise on his more radical proposals?

What if a national conservative and economically populist Greek businessmen existed and became Prime Minister in 2012, only to compromise on his more radical proposals?
On 7 September 2005, businessman and owner of the AEK Athens football club Ioannis Konstantinos announced he was leaving New Democracy and creating the Party of the Greek Nation (Κόμμα Ελληνικού Έθνους).
The new right-wing party also had the involvement of dissenters from LAOS and Golden Dawn, and several military officers. Konstantinos was announced to be the party's chairman, with Kyriakos Veuopoulos and Vasilis Stigkas also being founding members. On 11 February 2006, the KEE was officially registered with the Ministry of the Interior, allowing it to participate in that year's local elections.
The KEE fielded 42 candidates during the election, including in Athens and other PASOK strongholds like Crete and Thrace, but the majority of them ran in rural districts. Konstantinos self-funded the KEE's campaign efforts, and refused donations; the party elected two councillors, both of whom were in conservative small towns, and only won 0.34% of the vote in Athens, the majority of which is speculated to have come from AEK fans.
Throughout the rest of 2006, the KEE tried to capitalize on right-wing discontent with the European Union, and especially Turkey's proposed entry in the EU. It also fought against multiculturalism and immigration, and demanded that Germany pay Greece war reparations. The KEE manifesto (released to the public on 15 February 2006) did not make any mention of economics, which were not a winning issue for them before 2008, but in power, the party has pursued Keynesianism and economic nationalism.
On 10 January 2007, Konstantinos stepped down as AEK's official chairman, allowing him to focus on politics. During the legislative election, the KEE fielded 98 candidates for the Greek Parliament, and again refused to receive public funding,
its wealthy leader funding the campaign instead. Party campaigning focused on anti-immigration and eurosceptic views, supporting the restoration of drachma as a step towards Grexit, a points-based immigration system and border fence with Turkey, and a limit on how many refugees Greece could receive a year.
KEE eventually won 70,655 votes, 0.99% of the nationwide vote. Much of it came from rural districts that heavily supported ND, with football aficionados playing a lesser role, although many of them understood Konstantinos remained the power behind the throne. This low percentage of the vote (two percentage points below the electoral threshold) had an effect in the election, as ND fell two seats short of a parliamentary majority, forcing a confidence and supply agreement with the Popular Orthodox Rally (LAOS) to be formed.
During his second term, Kostas Karamanlis was forced to take a harder line on immigration and social issues in order to please his coalition partners, moving closer to the right wing of the ND, subsequently leading to the Party of Growth being formed as a centre-right schism from the ruling party. The 2008–09 financial crisis subsequently led to a vote of no confidence on his unpopular government, and PASOK won a landslide at the 2009 legislative election. Karamanlis also announced his opposition to Turkey's membership in the EU, and threatened to take the Macedonia naming dispute to the International Court of Justice, leading to international embarrassment.
The ND-LAOS coalition government followed a more conservative policy than previous administrations, opposing Turkish membership in the EU and threatening to sue Macedonia over its name.
The privatisation and deregulation policies of Kostas Karamanlis' first term were continued, as was European integration, generating tensions with ND's coalition partner while members of the ND establishment broke from the party to form the Party of Growth (KA). The KA's 2009 campaign was substantially hyped, but it won 168,953 votes and 2.46% of the vote, meaning it did not win any seats.
After his vote of no confidence pushed by the PASOK and dissatisfied ND politicians who opposed his inconsistent line and handling of the financial crisis, Karamanlis was replaced as its leader by Dora Bakoyannis, Foreign Minister of Greece, and formerly the first female major of Athens who hosted the 2004 Olympics. With two popular far-right parties, a broken economy and recently impeached head of government, voters agreed the ND was doomed from the start, and it had a historically poor result.
After the global economic crisis began in September 2008, KEE ran on economic interventionism, returning to the drachma, and protectionist trade policies, occasionally bringing up restrictions on immigration and law and order. Konstantinos continued to self-fund his party's campaign efforts, and often emphasized how his movement did not receive any government money, unlike the majority of competitors. On 28 May 2009, he and Georgios Karatzaferis agreed to a nonaggression pact between KEE and LAOS.
The 2009 general election produced a hung parliament for the second consecutive time, and again, one of the two major parties had to form a coalition government with a smaller, anti-estabilishment movement. George Papandreou, on the other hand, only agreed to govern as a 1970s social democrat and resist any further neoliberal measures.
KKE had a strong performance, getting double digits of the popular vote and 36 seats, while kingmaker Syriza and LAOS remained static. Over the next three years, Greece's economy continued to worsen, allowing KEE to form a majority government after the 2012 elections. Democratic backsliding and efforts to control government institutions have led to it governing Greece as of May 2024.
The PASOK-SYRIZA administration attempted to return to social democracy, but a crushing debt crisis made itself the main issue facing the country, and the left-wing coalition's policies failed to fix it.
As such, in 2011, the left-wing coalition government was replaced by a grand coalition of the ND and PASOK, which obtained a far greater margin in Parliament. Syriza leader Alexis Tsipras felt betrayed and broke with the PASOK, challenging it from its left and attempting to attract the working class and students.
In the meantime, the KEE, which proposed a Greek withdrawal from the Eurozone, protectionist economic policies and restrictions on immigration, continued to grow in support, attracting socially conservative workers who blamed immigrants and other minorities for the recession. In the 2010 local elections, it was the third most voted party nationwide and fourth in Athens, winning three city council seats in the capital, and actively used the internet for campaigning, the same strategy Konstantinos had used as a football chairman. By late 2011, it was polling second in general election surveys, behind Syriza, which was not blamed for the economic situation by voters due to having 15 seats.
Some pundits feared scheduling a new legislative election would hand over seats to the KEE, and those fears proved prescient, as it went from the second smallest to the largest party in Parliament, although 80 seats below a majority. The three days after the election were marked by pessimism, and the Athens stock market dropped noticeably.
On 7 May, Ioannis Konstantinos called Antonis Samaras, and offered to compromise on the Euro by supporting a referendum on the national currency instead. Polling showed the electorate to be split on whether or not to readopt the drachma, although the majority of them went on to vote for it, restoring Greece's sovereign currency. Later that day, he contacted Panos Kammenos, who was unaware of the compromise, and asked for him to support a right-wing coalition government; the ANEL leader accepted, and the governing majority was formed two days later – having a bare majority of 151 seats, and forcing Konstantinos to govern in a more moderate manner than expected.
The KKE lost eight seats to the Syriza, effectively realigning Greek politics between a national conservative and a democratic socialist parties. They have finished first or second in every Greek legislative election since, with SYRIZA having won the lastest due to the KEE administration getting unpopular.
The right-wing coalition went on to increase their seats the following year, as it did not take any further loans and instead focused paying down Greece's debt, implemented a balanced budget amendment, and closed corporate tax loopholes in order to stop tax evasion.
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2024.05.18 23:19 FakeElectionMaker The PASOK-SYRIZA administration attempted to return to social democracy, but a crushing debt crisis made itself the main issue facing the country, and the left-wing coalition's policies failed to fix it

The PASOK-SYRIZA administration attempted to return to social democracy, but a crushing debt crisis made itself the main issue facing the country, and the left-wing coalition's policies failed to fix it
As such, in 2011, the left-wing coalition government was replaced by a grand coalition of the ND and PASOK, which obtained a far greater margin in Parliament. Syriza leader Alexis Tsipras felt betrayed and broke with the PASOK, challenging it from its left and attempting to attract the working class and students.
In the meantime, the KEE, which proposed a Greek withdrawal from the Eurozone, protectionist economic policies and restrictions on immigration, continued to grow in support, attracting socially conservative workers who blamed immigrants and other minorities for the recession. In the 2010 local elections, it was the third most voted party nationwide and fourth in Athens, winning three city council seats in the capital, and actively used the internet for campaigning, the same strategy Konstantinos had used as a football chairman. By late 2011, it was polling second in general election surveys, behind Syriza, which was not blamed for the economic situation by voters due to having 15 seats.
Some pundits feared scheduling a new legislative election would hand over seats to the KEE, and those fears proved prescient, as it went from the second smallest to the largest party in Parliament, although 80 seats below a majority. The three days after the election were marked by pessimism, and the Athens stock market dropped noticably.
On 7 May, Ioannis Konstantinos called Antonis Samaras, and offered to compromise on the Euro by supporting a referendum on the national currency instead. Polling showed the electorate to be split on whether or not to readopt the drachma, although the majority of them went on to vote for it, restoring Greece's sovereign currency. Later that day, he contacted Panos Kammenos, who was unaware of the compromise, and asked for him to support a right-wing coalition government; the ANEL leader accepted, and the governing majority was formed two days later – having a bare majority of 151 seats, and forcing Konstantinos to govern in a more moderate manner than expected.
The KKE lost eight seats to the Syriza, effectively realigning Greek politics between a national conservative and a democratic socialist parties. They have finished first or second in every Greek legislative election since, with SYRIZA having won the lastest due to the KEE administration getting unpopular.
The right-wing coalition went on to increase their seats the following year, as it did not take any further loans and instead focused paying down Greece's debt, implemented a balanced budget amendment, and closed corporate tax loopholes in order to stop tax evasion.
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2024.05.18 22:55 RIZZOLI123 How do I know when to quit azelaic acid ??

I’ve been desperately trying to calm down my rosacea for the past 2 months. After years of wondering why I had such extremely sensitive skin/ finally realizing that the bumps on my cheeks weren’t acne, I talked to my doctor and got diagnosed with rosacea . Since then, I’ve been all over the place with treatment. I know I am lacking self control and not being patient which is part of why things aren’t getting better, but I also feel scared to put time into a product that may be making things worse!
I’m going to break down what I’ve tried and my hope is that someone can help me figure out if I should stick with a product, reduce % or frequency, or try something new all together??
March 25th - April 12th (almost 3 weeks): Wash face with FAB ultra repair - avene tolerance control creme (wait to dry) - Paula’s Choice Azelaic Acid Booster - avene cicalfate. During this time, I was honestly pretty happy for the first 5 days or so. Skin felt smooth, less red and tight and bumps were clearing. Then suddenly it was like I was flushing / rosy cheeks and waking up with new pimples on cheeks, chin and even forehead (where I don’t usually get rosacea).
April 12th - 15th Same wash/moisturizer routine but I got my rx for the azelaic acid 20% and tried that but felt like it was way too strong /stinging.
April 16 - 24th Went back to using Paula’s Choice Booster nightly, sandwich between moisturizers (waiting for them to dry in between). My skin was still inflamed, acne bumps on cheeks, temples and chin, perioral dermatitis bumps starting to pop up (something I dealt with 3 years ago). No improvements which was so discouraging because I felt like I had seen hope and improvements in the beginning!
April 24th - May 9th Cut back frequency of azelaic acid 10% use to every 3rd night. Skin was starting to look calmer and happier and less dry. I was so excited. It did seem like the mornings after using azelaic acid, I would wake up with a bit more texture/ a zit or two but nothing alarming.
May 10th - 15th Hugeeeee flare up! Azelaic acid was not doing a damn thing to help so I just a stopped use of it completely. I know the flare up was because we had a 90 degree day for the first time all year and I had to be outside for work. Sunscreen and a hat didn’t help unfortunately.
May 16th Out of total desperation to calm the irritation and bumps and feeling urgency because I leave for a bachelorette trip in a week - I read on here about Ivermectin 5% lice treatment and immediately ran out to get some. Tried it for a night and then got freaked out by the potential “die off period” and didn’t use it again.
Today: Now here I am, unsure if I should try azaleic acid again, give ivermectin a real effort, do nothing at all? I have rx for azaleic acid 15% too. Maybe I try that because it doesn’t have the salicylic acid like Paula’s Choice does, and maybe my skin didn’t like that?
PLEASE HELP! I need some guidance so I don’t drive myself crazy second guessing myself.
Thanks for tuning in to my saga lol
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2024.05.18 18:24 DoublleA Can somebody use undetectable AI for me?

Sorry if this sounds selfish but this is really only a one time thing for a friend. I need someone to use there undetectable AI account to paraphrase this please.
IntroductionThe rise of fast food chains in the United States from 2000 to 2010 had an impact on both the culture and economy. This period saw an increase in obesity rates among Americans, which coincided with the growth of these eateries. In this essay we delve into the connection between the expansion of fast food franchises and the obesity epidemic examining factors that influence health. Through an analysis of data, health studies and relevant literature our goal is to provide an understanding of how consuming food has played a role in fueling obesity during this particular decade, in America.The Growth of Fast Food Chains
Between 2000 and 2010 there was a rise in the fast food industry. Popular chains such as McDonalds, Burger King and Subway expanded their reach by opening stores to meet the demand for budget friendly meals. Data from the U.S. Census Bureau shows that the number of fast food eateries increased by around 20% during this timeframe (U.S. Census Bureau, 2011). This expansion made fast food more convenient for a range of people, including kids and teenagers.
Obesity Trends in the U.S. (2000 2010)
The prevalence of obesity in America has been on a trajectory during the early years of the 21st century. According to the Centers for Disease Control and Prevention (CDC) the rate of obesity among adults rose from 30.5% in 2000 to 35.7% in 2010 (CDC, 2011). Similarly among children and teens aged between 2 and 19 years old obesity rates increased from 13.9% to 16.9% over that period. This continuous increase signals a concerning public health issue with impacts on illness rates, mortality rates and healthcare expenses.
The Impact of Fast Food, on Eating Habits
food is commonly known for its levels of calories, excessive saturated fats, sugars and sodium with little nutritional value. These aspects of food are closely associated with weight gain and obesity. Studies show that regular consumption of food is linked to consuming calories and maintaining poor eating habits (Bowman & Vineyard 2004). Research conducted by Pereira et al. (2005) revealed that individuals who ate food than twice a week were more likely to gain weight and develop insulin resistance compared to those who consumed it less frequently.
Influence of Socioeconomic Factors
The easy availability and affordability of food make it an attractive option for people with incomes. Fast food establishments are often concentrated in low income areas where residents have limited access to dining choices (Powell et al. 2007). This situation, referred to as "food deserts " , worsens the issue of obesity because disadvantaged groups tend to rely on food as their main source of nutrition.
Impact of Advertising and Promotion
The aggressive advertising tactics used by fast food companies also have a significant influence on eating behaviors particularly among young individuals, like children and teenagers.
Many businesses invest sums of money each year in marketing showcasing their products across platforms, like TV, the web and social networks. Kids are especially influenced by these strategies that highlight the appeal and ease of food reinforcing harmful dietary patterns early on.
The impact of obesity, on health is significant and variedObesity is a factor in chronic illnesses like type 2 diabetes, heart disease, stroke and certain cancers (Flegal et al., 2012). The rise in obesity rates has led to an increase in health issues putting a strain on the healthcare system. The financial implications of obesity are also noteworthy with studies indicating that medical costs linked to obesity made up around 10% of healthcare expenses in the United States during that time (Cawley & Meyerhoefer 2012).
Policies and public health effortsIn response to the escalating obesity crisis, different policies and public health efforts have been put into action at state and local levels. These initiatives aim to encourage eating habits through measures like food labeling requirements, restrictions on advertising foods to children and campaigns raising awareness about the risks of obesity (Koplan et al., 2007). Schools have been a point for intervention well, with endeavors to enhance the nutritional value of school meals and boost physical activity among students.ExamplesVarious real life examples and stories showcase the effectiveness of taking action to address the issue of obesity. For example, New York City put in place a set of strategies to combat obesity, such as displaying calorie information on menus and prohibiting trans fats in restaurant dishes. These initiatives led to improvements in people's eating habits and a slight decrease in obesity levels, within the community (Dumanovsky et al. 2011).ChallengesThe obesity epidemic still poses challenges despite the efforts to address it. Unhealthy eating habits deeply ingrained in society, the presence of the fast food industry and disparities in status all add layers of complexity to this issue. Moving forward it is crucial to focus on creating an environment that encourages choices for vulnerable communities. This entails advocating for policies that restrict the marketing of foods to children, enhancing access to options in low income areas and urging food companies to improve the health profile of their products.
Psychological marketingWhen it comes to food marketing companies go beyond advertising tactics by leveraging deep rooted psychological triggers that influence consumer behavior. Bright colors, catchy tunes and recognizable mascots are commonly used in food ads to build a memorable brand image. This technique is particularly effective with audiences like children and teenagers who're more susceptible and likely to develop lasting brand loyalties. Research indicates that exposure to these advertisements can lead children to prefer calorie, nutrient foods ultimately impacting their dietary decisions and contributing to weight gain (Boyland & Halford 2013).The impact of portion sizes
One overlooked but significant factor contributing to the obesity crisis is the increasing sizes of portions served by food chains. Over time portion sizes have substantially grown, with meals exceeding the recommended calorie intake for a single meal. Young and Nestles (2002) study reveals that fast food item portions have expanded over the years with some items now more than double their size. This phenomenon of "portion distortion" results in calorie consumption as individuals tend to eat when faced with larger servings often underestimating the actual caloric content.
Changes in lifestyle and time constraints
The contemporary way of life characterized by schedules and time limitations has also played a role in the heightened dependence on fast food. With an increase in dual income households and longer work hours many people find themselves lacking the time to cook meals. Fast food emerges as a solution offering cost effective options that align with busy routines. Nonetheless this convenience comes at a price as frequent consumption of food is linked to dietary patterns and increased calorie intake contributing to the surge in obesity rates (Smith, Ng & Popkin 2013).Another significant measure involves restricting the promotion of foods to children. By reducing kids exposure to food ads policymakers aim to lessen the impact of marketing on their eating habits. Some cities have also imposed taxes on beverages and unhealthy foods in an effort to discourage consumption through penalties. While the effectiveness of these strategies may vary they mark progress in combating the obesity crisis.
Approaches Rooted in Communities
Community based strategies for addressing obesity highlight the importance of initiatives and grassroots movements. Programs that concentrate on enhancing access to foods encouraging activity and educating community members about healthy eating have shown positive outcomes. For example community gardens and farmers markets can offer produce to residents living in areas with access to healthy food options promoting better dietary choices. Schools and community centers can also play a role by providing nutrition education and physical activity programs.
The Impact of Technology
Technology has increasingly become an asset in the battle against obesity. Mobile applications and wearable gadgets enable individuals to monitor their calorie intake and exercise levels offering feedback and motivating lifestyle choices.
Furthermore social networking sites can play a role, in advocating for public health initiatives and sharing details on diet and wellness. Although technology isn't a solution to the issue of obesity it provides avenues to involve people and groups in embracing healthier habits (Stephens & Allen 2013).
Future Directions and Recommendations
The approach to tackling obesity needs to be multi-faceted and should involve collaboration between government departments, health workers, local communities, as well as the food industry. In future, there is need for more efforts in creating an atmosphere that supports healthier selections particularly among the disadvantaged groups. This means that one should continue to campaign for policies aimed at reducing children’s exposure to unhealthy food advertisements, improving availability of healthy foods in deprived neighborhoods and encouraging manufacturers in the food sector to change their products into a healthier version.
Further still public health campaigns will try and focus on having balanced diets regularly done exercises. Schools and offices can succeed by developing well-structured meals alongside opportunities for exercising. More research is also needed to understand why some people are poor eaters or overweight than others.
Policy Proposals
To further combat the menace of overweight, policy makers should think about enacting a variety of evidence-based strategies. Some of them could be: Sugar-Sweetened Beverage Taxes: Taxes on sugary drinks can decrease consumption and raise funds for public health projects. Zoning Regulations: By controlling the number of fast food restaurants in given areas, intake will subside and encourage establishment of grocery stores among other healthier alternatives.Menu Labeling Laws: This makes sure that restaurants indicate calorie counts as well as other nutritional information to assist customers in making informed choices. School Nutrition Standards: Schools meals and snacks in the course of learning ought to meet recommended nutrition levels so that students are eating healthy. Addressing Behavioral FactorsBehavioral interventions also play a significant role in dealing with obesity. Cognitive-behavioral therapy (CBT) and other psychological approaches aid individuals to develop better eating habits and deal with triggers involved in overeating. Programs addressing weight control which incorporate behavior change counseling together with diet and exercise components show promise towards helping individuals achieve successful long term weight loss.Long-Term Commitment and Sustainable Change
Society must collectively make a commitment that will last over a long period to reduce obesity rates. The approach should be ongoing and flexible enough to accommodate changing circumstances and new information. For this change to be lasting, there must be continuous investment in public health infrastructure, research, and education. Therefore, significant strides can be achieved in reducing obesity rates by nurturing a culture that appreciates wellness.
Cultural Shifts and Public Perception
In addressing the obesity epidemic another critical factor is shifting public opinion as well as cultural norms with regards to food and health. The acceptance of fast food and oversize portions as normative has been one of the major drivers towards unhealthy eating habits over the past few decades. This would involve public health campaigns focused on what constitutes healthy balanced meals and promoting on good home cooked fresh meal benefits instead. To change public perception cooking classes nutrition workshops media campaign advertising preparation advantages of healthy meals at home for instance.
Strengthening Health Care Interventions
Routine screenings, counseling and support for weight management by health care providers are crucial in handling obesity. Obesity prevention and treatment should be integrated into primary care to ensure consistency and comprehensiveness in people’s health. Personalized advice can be availed by the healthcare practitioners and also set realistic targets as well as referring patients to dietitians or structured weight loss programs.
Advancing Research and Use of Proven Practices
To better understand the intricate contributors to obesity and curate effective interventions, it is important to sustain research. Longitudinal studies that follow diet patterns, activity levels, and disease outcomes offer useful information on how to prevent or reduce obesity. By exploring behavioral, environmental and genetic factors that affect obesity, this will enable us to make interventions that are specific for different populations and situations as well.
Conclusion
The period between 2000 and 2010 registered a sharp increase of obesity rates that is closely linked to the spread of fast food outlets across America. This public health menace can only be fought with multidimensional approaches that will change public attitude, improve education, enhance corporate accountability and support inclusive research plus health care interventions. By creating an environment where good health is appreciated through provision of necessary resources and support, we can achieve significant milestones in curbing cases of obesity within our population as well as overall improvement in their welfare.
Citations:
Boyland, E.J. & Halford, J.C.G., 2013. Television advertising and branding. Effects on eating behavior and food preferences in children. **Appetite**, 62, pp.236-241.
Brownell, K.D. & Frieden, T.R., 2009. Ounces of prevention—the public policy case for taxes on sugared beverages. **New England Journal of Medicine**, 360(18), pp.1805-1808.
Drewnowski, A. & Specter, S.E., 2004. Poverty and obesity: the role of energy density and energy costs. **American Journal of Clinical Nutrition**, 79(1), pp.6-16.
Krieger, J.W., Chan, N.L., Saelens, B.E., Ta, M.L., Solet, D. & Fleming, D.W., 2013. Menu labeling regulations and calories purchased at chain restaurants. **American Journal of Preventive Medicine**, 44(6), pp.595-604.
Ogden, C.L., Carroll, M.D., Kit, B.K. & Flegal, K.M., 2014. Prevalence of childhood and adult obesity in the United States, 2011-2012. **JAMA**, 311(8), pp.806-814.
Smith, L.P., Ng, S.W. & Popkin, B.M., 2013. Trends in US home food preparation and consumption: analysis of national nutrition surveys and time use studies from 1965-1966 to 2007-2008. **Nutrition Journal**, 12(1), p.45.
Stephens, J. & Allen, J., 2013. Mobile phone interventions to increase physical activity and reduce weight: a systematic review. **Journal of Cardiovascular Nursing**, 28(4), pp.320-329.
Story, M., Kaphingst, K.M., Robinson-O'Brien, R. & Glanz, K., 2008. Creating healthy food and eating environments: policy and environmental approaches. **Annual Review of Public Health**, 29, pp.253-272.
Walker, R.E., Keane, C.R. & Burke, J.G., 2010. Disparities and access to healthy food in the United States: A review of food deserts literature. **Health & Place**, 16(5), pp.876-884.
Young, L.R. & Nestle, M., 2002. The contribution of expanding portion sizes to the US obesity epidemic. **American Journal of Public Health**, 92(2), pp.246-249.
Fulkerson, J.A., Story, M., Neumark-Sztainer, D. & Rydell, S., 2008. Family meals: Perceptions of benefits and challenges among parents of 8-to 10-year-old children. **Journal of the American Dietetic Association**, 108(4), pp.706-709.
Huang, T.T.K., Drewnowski, A., Kumanyika, S.K. & Glass, T.A., 2009. A systems-oriented multilevel framework for addressing obesity in the 21st century. **Preventing Chronic Disease**, 6(3), A82.
Kumanyika, S.K., 2008. Environmental influences on childhood obesity: Ethnic and cultural influences in context. **Physician and Sportsmedicine**, 36(1), pp.45-51.
Larson, N.I., Story, M.T. & Nelson, M.C., 2009. Neighborhood environments: Disparities in access to healthy foods in the US. **American Journal of Preventive Medicine**, 36(1), pp.74-81.
Ludwig, D.S. & Pollack, H.A., 2009. Obesity and the economy: from crisis to opportunity. **JAMA**, 301(5), pp.533-535.
Powell, L.M., Chaloupka, F.J. & Bao, Y., 2007. The availability of fast-food and full-service restaurants in the United States: associations with neighborhood characteristics. **American Journal of Preventive Medicine**, 33(4), pp.S240-S245.
Sallis, J.F., Floyd, M.F., Rodríguez, D.A. & Saelens, B.E., 2012. Role of built environments in physical activity, obesity, and cardiovascular disease. **Circulation**, 125(5), pp.729-737.
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2024.05.18 16:11 aK1donn Savvy Shopping: Your Guide to Scoring the Best Deals and Saving Money

1. Create a Budget and Stick to It

Before you start shopping, set a budget to control your spending. Make a list of the items you need and stick to it. This helps you avoid impulse buys and ensures you stay within your financial limits.

2. Shop at the Right Time

Timing can significantly impact your savings. Here are some key periods to watch for:

3. Use Coupons Wisely

Coupons are a powerful tool for saving money. Here’s how to maximize their use:

4. Compare Prices

Before making a purchase, compare prices across multiple retailers. Use tools like Google Shopping, ShopSavvy, and PriceGrabber to ensure you're getting the best deal. Don’t forget to check for price-matching policies that many stores offer.

5. Buy in Bulk

When non-perishable items or household staples are on sale, buy in bulk to save money over time. Ensure you have adequate storage space to avoid waste. Items like toilet paper, canned goods, and cleaning supplies are ideal for bulk purchases.

6. Take Advantage of Rewards Programs

Join rewards programs at your favorite stores to earn points on your purchases. These points can often be redeemed for discounts or free products. Credit cards with cash back or rewards points are also a great way to earn while you shop.

7. Utilize Cash Back Offers

Cash back websites and apps like Rakuten or Swagbucks give you a percentage of your purchase back when you shop through their links. This is an easy way to earn money on purchases you’re already making.

8. Shop Clearance Sections

Always check the clearance sections in stores and online. These areas often have deeply discounted items that are perfectly good but may be out of season or overstocked.

9. Look for Free Shipping

Shipping costs can add up quickly, so look for retailers that offer free shipping. Many stores provide free shipping on orders over a certain amount. Use tools like FreeShipping.org to find free shipping codes and offers.

10. Plan Meals Around Sales

Base your weekly meal plan on what's on sale at your local grocery store. Check weekly ads and use grocery store apps to find the best deals. Planning meals around sales ensures you buy what’s discounted, saving you money on groceries.
By following these tips, you can make smarter shopping decisions, save money, and make the most out of every dollar. Happy shopping!
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2024.05.18 15:45 LargeLawyer224 HELP

HELP
So I’ve been told by dermatologists that I have perioral dermatitis. They’ve given me everything from hydrocortisone, steroid creams and face washes. As well as now I’m taking doxycycline antibiotics. But my main concern is how there’s a huge red/brown VERY noticeable area around my mouth. It almost looks like burns from maybe using too much on my face??? I don’t think it’s JUST hyperpigmentation but how do I get RID of it. Completely. It’s literally only around my mouth.
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2024.05.17 23:19 ObjectiveMortgage905 Progress pics

Progress pics
I have had bouts of hair loss for the past 10 years. Twice were classic TE from weight loss and divorce. The most recent episode was not classic. I struggled thinking maybe it was CTE, AGA or a reaction to hair dye. I saw two derms and a trichologist. Ultimately I was diagnosed with seborrheic dermatitis exacerbated by hair dye. These photos are mainly since starting the hair max headband in March. The other stuff I’ve been doing since January. Included photos from last year at my worst.
My current routine: wash hair every other day or more. I use Bumble and Bumble volume shampoo and seaweed conditioner. I use the Omnilux red light mask on my scalp a total of 20 minutes at different angles trying to part my hair to get benefit. With a recommendation from my trichologist in March, got the hair max headband and use that 3x/week. I have taken oral ketoconazole 200mg weekly for 8 weeks. I took ivermectin orally for the demodex.
Things that seem to help: shower and whole house water filter, red light mask on my scalp, eating meat for the first time in years, eating red meat three times a week, spirulina, chlorella, beetroot, beef liver and oyster, zinc, washing hair more often - at least every other day, completely stopped dyeing my hair. Clobetasol definitely helped but I didn’t want to take long term bc it caused folliculitis on multiple occasions. Also noted that I had been on several long courses of doxycycline for perioral dermatitis when my hair was growing at its best (inflammation?)
Things I’ve tried that didn’t help: vegamour, nutrafol (took 6 months and it gave me nightmares, Mary Ruth multivitamin, head massages (worsened inflammation and loss).
Things that seem to correlate every shed: going too long without washing, hair dye, head massage, microneedling, forehead botox, notice tiny white flakes before every shed. Zero hx of seb derm in the past. Just diagnosed with Demodex in the brows and eye lashes. Tea tree oil fixed immediately.
I’ve never taken minoxidil, spironolactone etc.
I used to use sulfate free IGK but I shedded more so I think it didn’t clean my scalp enough.
Happy Cappy zinc shampoo made wayyy worse and Dr. Donovan’s blog said it could.
I do not use Any dandruff treatment shampoos.
I do plan on trying to dye my hair using only to blend gray. I have considered henna bc it’s the only option without PPD or MEA but I’ve never done my own hair and don’t really want to at this point.
By the way MEA is in “no ammonia” hair dye and is 80% more likely to cause dermatitis and hair loss than ammonia. I am pretty convinced that’s what my issue is honestly. My new stylist said you have to wash immediately so it will stop processing which I have never done because I like the coloblow out.
So using advice and anecdotes I’ve gathered I plan to use clobetasol for two days prior (dr. Donovan recommendation), wash my hair the day of the appt and put conditioner directly on my scalp (trichologist rec), wash my hair immediately after and daily for a while. May use clobetasol after.
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2024.05.17 05:15 Equal-Respect-3000 JCPenney Promo Codes - Up to 50% OFF

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2024.05.16 19:20 mediumonplus JCPenney Promo Code for May 2024

Visit this page for JCPenney Promo Code for May 2024. The website offers a wide selection of coupons, promo codes, and discount deals that are updated regularly, just visit the website to find the perfect one for you.
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2024.05.16 17:42 karinamarinasarina Should I go back to retinol?

Posting on here for some advice on whether to start using retinol again… I have a long story with acne and getting perioral dermatitis recently - really need some advice
For context, I have struggled with acne my entire life, from the age of 11 I was on multiple treatments including creams and antibiotics to try and control my spotty and oily t-zone. At the age of 17 I had a terrible break out on my cheeks, it was really severe and I had never had acne like that before. After numerous things I ended going on the contraceptive pill and that completely cleared my skin. I was on the pill for about 5-6 years but it really affected my mental health, depression, anxiety and mood swings were horrible so I finally came off it before the age of 23.
When I came off the pill I became quite nervous that all my acne would come back, I began getting spots here and there, and after seeing the rave about tretinoin online I decided to give it a go. It definitely wasn’t the best decision from me, I got the retinol uglies, I went in with 0.5 which was definitely too strong too quick and I was losing hope after a few months. I think my skin was just TOO exfoliated, I couldn’t figure out a routine and I think I was using too many products.
I then switched to Dermatica and got prescribed Adapalene 0.2% / Clindamycin 1% / Niacinimide 4% This felt better but my skin was continually peeling, it looks glowy now that I look back on pictures but I was still getting spots. Nothing drastic but I was definitely searching for that glass skin look.
After 6 months they switched my prescription and removed the Clindamycin (due to resistance to that ingredient I think you can only take it for 6 months). This was before Christmas time in 2023, the weather became really extreme and my skin suffered. I thought it was just the weather and I would lather in moisturisers and continue to only use Dermatica every 3rd night but my skin would not stop peeling. I contacted Dermatica and told them my side effects and they said that my skin is just getting used to it. I began to get a dry patch near my mouth which slowly got worse, I thought this was because of the weather but I got a lot of redness around my mouth and looking online I felt like I had developed perioral dermatitis.
Long story short I did have perioral dermatitis. I stripped my skincare routine to be VERY minimal and began taking antibiotic, I was prescribed Lymecycline from my doctor for 3 months, I also started using Azelaic Acid after following Dr Sam Bunting advice online.
Now that I have finished my antibiotic, I am still continually getting spots, it almost feels a tad worse now that I’ve finished the antibiotic (Lymecycline is also prescribed for acne as well as POD). My skin feels really clogged and my forehead just has a lot of tiny spots, I keep getting breakouts and I just want to not have to deal with it all the time, it feels NEVER ending that I have acne for the rest of time at the moment.
Here is my current skincare routine: AM - Wash face with water - The Ordinary Caffeine Solution under my eyes - The Inkey List Azelaic Acid 10% - The Inkey List Vitamin C 15% (just started using this to brighten marks) - The Inkey List Niacinimide (for my oiliness) - The Inkey List Omega Water Cream (if my skin is feeling moisturised I don’t use this) - Paula’s Choice Clear SPF 30 Fluid
PM - Remove make up with The Inkey List Oat Cleansing Balm - Wash face with Dr Sam Bunting Flawless Cleanser - Dr Sam Bunting Flawless Neutralising Gel - this has 2% salycilic acid, 5% azelaic acid, 0.5% bakuchiol, 5% squalene (started using this in the past week now that I have finished my antibiotic and I only put it on my spots, most nights in the week) - Sometimes I may use Paula’s Choice BHA or AHA (probably once a week and not at the same time as the gel above) - Cosrx Snail Mucin (if my skin is feeling dry or I have used an exfoliator) - The Inkey List Omega Water Cream OR Aveeno Oat Restorative Night Cream
Treatments: - I’ve got the Omnilux Red Light Therapy mask and I use it a few times a week (my skin feels very hydrated and plump from this) - I’ve been using a high frequency wand a few times a week on my spots
I’ve been contemplating using The Ordinary Retinal 0.2% maybe once or twice a week in the evenings, but I’m just really nervous and not entirely sure whether it’s worth it. My skin did look good on Dermatica (apart from the peeling) and definitely way less clogged than I feel now, so I feel really tempted especially hearing that retinal is really good.
Considering I’ve been using Azelaic Acid daily for 3 months now I feel like my skin is slightly less sensitive, but I’m VERY worried I will fall into a trap and over exfoliate if my spots still continue, I’m a stress picker and I just want them gone so if one appears I just need to do something to it. I’m also very scared of the retinol uglies, I’ve started a new job recently and I’m definitely worried it will crush my confidence on a daily, as already I get quite down about spots.
Does anyone have any advice if retinal is a good idea?
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2024.05.16 13:18 _mardavi Red bumps on nose bridge

(I'm sorry for my English, it's not my language). In November I began to notice spots like that in my nose, by February it was in my forehead, nose, cheeks along with weird reddish and purple colors on my nose. I was diagnosed with rosacea and began to take doxycycline and use Metronidazole 1% + Ivermectin 1% all over my face. I did that in October of last year because it all started as a perioral dermatitis. In November, I was using the prisme poudre de libre powder and thought it was that. My face was clear, besides random spots in my cheeks and apples like in the picture. Recently, I was using one of my favorite powders, Hourglass Veil, and the spots started again (I don't use powder in my nose though). But I also started de Vanicream two days ago, because it's been months that I'm using Osmia Black Clay Soap, and it's AWESOME, but I HATE bar soaps for face. The Vanicream felt great, smooth in my face, but I think that made my bumps redder and in this morning I woke up with these nose spots even worse. Any ideas? Thank you!
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2024.05.15 16:05 healthmedicinet Health Daily News May 14 2024

DAY: MAY 14, 2024

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2024.05.15 13:52 wakamegs JCPenney Discount Code for May 2024

Visit this page for JCPenney Discount Code for May 2024. The website offers a wide selection of coupons, promo codes, and discount deals that are updated regularly, just visit the website to find the perfect one for you.
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2024.05.14 18:10 styleesmave JCPenney Coupon Codes of May 2024

Visit this page for JCPenney Coupon Codes of May 2024. The website offers a wide selection of coupons, promo codes, and discount deals that are updated regularly, just visit the website to find the perfect one for you.
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2024.05.14 16:30 princeherb1 Need help on deciding when to re-introduce tret

I was prescribed tret 0.25 alongside benzoyl peroxide since October 2022 then 0.5 in july 2023 and I’ve had meh results so I was recently prescribed up to 1% this past April. However I decided to take a break from treatment since I’m pretty sure I’ve damaged my moisture barrier from using treatment daily (BP in AM) and I wanted to focus on repairing my barrier. After about two weeks of stopping I had a horrible breakout around my chin which I’m pretty sure was perioral dermatitis caused by a new toothpaste and cleansing balm. It’s cleared a bit since then and I was prescribed doxycycline last week to help. But now I’m at a point where I’m not sure when to re introduce my treatment. I feel like my skin barrier needs a little more time to heal but I’m afraid I might scar from this recent breakout if I don’t act now. Tret has been ok for me but I’m curious to see if the 1% will finally do the trick, however I really want to help my moisture barrier as my skin is pretty oily and dehydrated at the moment. Any advice would be appreciated!
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2024.05.14 06:15 theconstellinguist Borders, Power Shifts, and Gender: Power Shifts at Border Checkpoints Seem to be Processed on Women's Bodies in Ukraine and Russia: Patterns of Gender-Based Violence in Conflict-Affected Ukraine: A Descriptive Analysis of Internally Displaced and Local Women Receiving Psychosocial Services

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9240103/

Patterns of Gender-Based Violence in Conflict-Affected Ukraine: A Descriptive Analysis of Internally Displaced and Local Women Receiving Psychosocial Services

Arbitrary Displacement Is a Structural Rot that Hegemonizes Economic Abuse and with it Economic Collapse
Checkpoints for the displaced showed the most violence, literally predating on women when they were the most vulnerable by armed men.
Almost 8% of violent incidents against displaced women occurred at checkpoints or at reception centers for internally displaced persons (IDP) and 20% were perpetrated by armed men.
Majority of Ukrainian female respondents described their household economic situation as bad or very bad (59%)
A survey of internally displaced persons (IDPs) in Ukraine found that a majority of respondents described their household economic situation as bad or very bad (59%), and only 22% held regular employment (Roberts et al., 2017).
Women fleeing violence are most likely to be exposed to sexually violent men exactly at the moments they were most expecting protection. This suggests a pattern of men who watch for the female victims of their enemies, and then violate them when they come to them, simply out of nationalist/ethnicist hate crime, with no care about their status as a victim.
Meta-analytic findings estimate a 21% prevalence of sexual violence among female refugees and IDPs (Vu et al., 2014).
A 2014 national survey conducted shortly after the start of the conflict found that 19% of 15–49 year old women had experienced violence since the age of 15 compared to 17% in 2007 (Martsenyuk et al., 2014).
Displaced women were more likely to experience sexual violence
Furthermore, we hypothesized that among GBV survivors: 1) proportionally more violent acts against displaced women would be non-domestic and associated with combat operations (i.e., demobilized and active governmental and non-governmental soldiers); 2) displaced women would be more likely to experience sexual violence than local women; and 3) patterns of reporting and referrals would differ depending on a woman’s residency status.
UN Women’s Framework for emergency response and preparedness (UN Women, 2013) was used
The adaptation process followed the recommendations of the GBV-IMS Rollout Guidelines (UNFPA, n.d.) and the UN Women’s Framework for emergency response and preparedness (UN Women, 2013), and entailed piloting the tool with several mobile teams and incorporating the feedback from the field.
Definition of internally displaced person
Ukrainian law defines an internally displaced person as “a citizen of Ukraine, a foreigner or a stateless person who is in the territory of Ukraine legally and has the right to reside permanently in Ukraine, and who was forced to leave his place of residence due to armed conflict, temporary occupation, widespread violence, human rights violations or emergencies of natural or man-made nature” (On Ensuring the Rights and Freedoms of Internally Displaced Persons, 2014).
Forced marriage with economic abuse followed with rape and sexual assault
Determination of GBV type was made by mobile team members using the GBV-IMS classification tool (UNFPA et al., 2011). The form instructs providers to select only one GBV type per case based on a series of questions asked in a specific order, as follows: 1) rape (if any type of penetration occurred); 2) sexual assault (if there was unwanted sexual contact); 3) physical assault (if there was physical battery); 4) forced marriage; 5) economic violence (in cases of denial of resources, opportunities, or services); 6) psychological or emotional abuse (if the incident involved insults, name-calling, and humiliation); and 7) no GBV (if none of the above). If, for example, a woman reported experiencing unwanted sexual contact, the provider would classify the case as “sexual assault” and continue to the following section.
One in five women who experienced violence were unemployed, showing these violent perpetrators may keep their victims from employment or sabotage their employment purposefully to put them in harm’s way.
More than one in five (21.6%) women who experienced violence were unemployed, with no differences between the groups. Overall, slightly less than one-third (30.7%) of the women engaged in unpaid labor such as elder and childcare, with significantly higher proportions among local women. Proportionally more displaced women had a professional occupation (24.6% vs. 20.0%, p<0.001).
78.3% of women reported that a man raped them. Half of the women reported psychological abuse in addition, showing many rapists are psychologically abusive before and after as a tell-tale sign.
More than three-quarters (78.3%) of women reported that a man was the perpetrator. In nearly half of the cases, the perpetrator was an intimate partner (49.5%); and in roughly one in five (21.8%) a family member. Psychological abuse (48.4%) was reported by almost half of the women (See Table 2).
Compared to local women, proportionally more displaced women reported an incident of rape or sexual abuse (3.1% vs. 2.1%, p<0.001) or economic abuse (23.4% vs. 14.4%, p<0.001).
Gender based violence affects one million women annually in Ukraine
GBV is a grave human rights violation that affects an estimated one million women annually in Ukraine (Barrett et al., 2012). Social disruption and frail economic conditions in humanitarian settings further aggravate women’s vulnerability to violence, particularly for displaced women (Stark & Ager, 2011; Stark et al., 2017). This analysis supports our primary hypothesis that the experience of violence differs by survivors’ residency status. Specifically, we found differences in terms of relationship to the perpetrator, type of violence experienced and access to care between local and displaced women.
Checkpoints, or borderlines, nebulous zones of power shifts were huge points of violence to Ukrainian women, showing power shifts are often signaled by violence, especially to the most vulnerable.
Notably, 20.0% of displaced women in our sample experienced violence at the hands of armed men compared to 5.3% of local women. We also found that checkpoints between government-controlled and non-government–controlled areas and IDP reception centers posed a particular risk for displaced women in our study.
38% more displaced women reported experiencing sexual violence than local women, meaning people were actively preying on people who were displaced, not protecting them. This shows Ukrainian women are at huge risk of opportunistic rape by the very men pretending to be safe.
Whereas sexual violence was the least common type of reported violence, 38% more displaced women reported experiencing sexual violence than local women.
Ukrainian women come from a long history of corrupt police, so they did not report to the police because the police do not work for them and never have. That is not their fault; it is their country and area’s fault.
Studies in conflict-affected Ukraine found that a majority of survivors were unwilling to report GBV incidents to the police, particularly among internally displaced women (UCSR, 2018).
Because of this violence around the very people that were supposed to protect them, Ukrainian women are less likely to file a police report. Displaced women were even more unlikely. It is an intelligent decision to not have a faith that has been factually and with evidence violated repeatedly.
we found that displaced women were less than half as likely than local women to have filed a police report.
Younger women seek gender based violence services more than older women, showing Ukrainian women are often being targeted for their fertility and not receiving justice can help them remain to be seen as a fertility commodity instead of a human being, making European countries very wary of the nation seeing how their women are treated. Women's rights feature largely in European economic inclusion.
For example, among GBV survivors in Ukraine, younger women seek services for GBV more often than older women (41% of those aged 15–29 vs. 26% those aged 40–49) (Martsenyuk et al., 2014). Therefore, this analysis is not representative of all women experiencing violence.
Domestic violence within the ranks of the warring country increased during war for Ukrainian women, instead of coming together in solidarity and mutual support
Studies in complex emergency settings have found stigma among GBV survivors, normalization of domestic violence during times of conflict, unwillingness to report men living in the home for fear of forced military recruitment, and reluctance to involve law enforcement as major reporting barriers, especially among displaced women survivors of violence (Ager et al., 2018; Stark & Ager, 2011).
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9240103/
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