How septra ds works

Homestuck

2010.07.31 14:11 Homestuck

A subreddit for Homestuck, Beyond Canon and the works of Andrew Hussie. The largest, most active Homestuck community. Submit fanart, cosplay and discussions of all kinds! The Homestuck Discord exists at https://discord.gg/homestuck if you want to chat with fellow fans.
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2010.09.24 19:01 The Real Driving Simulator

A subreddit dedicated to the Gran Turismo series. Come here for news, discussion, speculation, and help. Post your garage collection, strategies and techniques, photos and everything in between!
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2010.07.06 18:09 Wo1ke Café

We aim to be the reddit version of your local cafe. We welcome discussions related to coffee, other “cafe” food and drink, and cafe life. Like real cafes have galleries or stages, we host weekly themes as an addition post topic, and we host special event days to try and mimic specialty bookings: memes on Mondays, Thursday is Open Mic night, and cap off the week with Sunday Story Slam. Come on in, take off your coat, and sit down to relax.
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2024.05.19 08:25 Nice-Succotash-6802 Anyone have suggestions about crossing Chiron/Neptune?

Anyone have suggestions about crossing Chiron/Neptune?
[[Summary and question below, since it's confusing]] Hi, I'm quite new about astrology so I'm not sure how to interpret these correctly. The last time I lived in crossing Chiron/Neptune was a hectic. Both my mental and physical health was bad, but I don't know if it was due to Pluto/DS too or not. The images I attached below are astrocartography of where I have been wanting to live for a very long time and my natal chart. I planned to quit my current job at JupiterAC/PlutoMC since I've been fighting with my boss since before I moved here and I'd say I don't want to work with him anymore. I planned to move to where I wanted, but since it has Chiron/Neptune, I'm scare.
If the above info is confusing, here's summary.
Place A, where I lived for 6 months and my life was a hectic: SunDS, PlutoDS, crossing MercuryDC/Moon's nodeIC, VenusMC/ChironDC, ChironDC/NeptuneMC, VenusDC/SaturnMC, MoonMC/NeptuneDC
Place B, where I live now but planning to move elsewhere: JupiterAC/PlutoMC
Place C, where I have been wanting to live, but has weird stars: as in the pic
Question: Should I move to place C or stay in B?

https://preview.redd.it/w4jo4xb3ub1d1.jpg?width=797&format=pjpg&auto=webp&s=aa245624c3aea8d6ec70457a50e1e77ea6dc4d3a
https://preview.redd.it/yh4uuo00ub1d1.jpg?width=628&format=pjpg&auto=webp&s=72bbf5886e14b6b8e19698c07dc9f9d0476bed8d
submitted by Nice-Succotash-6802 to astrosignature [link] [comments]


2024.05.19 08:00 prankousky start backup 2 after backup 1 has finished (instead of at specific time)

Hi everybody,
I am using Hyper Backup to back up files from my DS918+ onto my DS413.
Each of these backups are run at specific times, which I had to configure when creating each backup.
However, my DS413 only runs for these backups. That means that my DS413 boots at a specific time and shuts down at another specific time.
Here is an example
* DS413 power on 11:55 * DS918 start backup 00 at 12:00 * DS918 start backup 01 at 12:45 * DS918 start backup 02 at 13:30 * DS918 start backup 03 at 15:00 * DS413 shutdown at 16:30
This works fine. However, depending on the size, backups take different amounts of time (of course). I planned 45 minutes for backup 00; however, let's say there is nothing to backup... in this case, it would make much more sense to run backup 01 at 12:05 (or, to be clear, at whatever time my DS realizes that backup 00 has finished already).
However, the current configuration will run backup 00 at 12:00 and wait until 12:45 no matter what. I would like to start backup 01 as soon as backup 00 has finished; if it's done by 12:05, start backup 01 by 12:05. If it takes longer than expected, for example, until 13:00, then don't start backup 01 until backup 00 has finished.
Is this possible? If so, how can I achieve this?
Why am I even doing this? Well, I have tried to use one single Hyper Backup task to backup everything at once. Multiple attempts failed. They took days each at the time (multiple TB have to be backed up) and failed eventually, so I figured I'll split this one backup task into many smaller ones. There haven't been issues with this.
Except that I have to schedule each backup at a specific time, which results in either gaps (if backups finish earlier) or overlap (in which case backup 01 will start while backup 00 is still running).
I am doing all this to conserve energy. DS413 only needs to run when backups are being synced. If the DS could improve the duration of this by running the next backup related to the previous one, this would allow me to shut down the DS413 sooner (because, if only one of those four backups were to run, this would be determined by an external script and also externally send a command to power off the DS413 way sooner than if it were to wait until a specific, hard-coded time).
Thank you in advance for your ideas :)
submitted by prankousky to synology [link] [comments]


2024.05.19 06:42 kainike Delusional Filipino actually turned out fine

im a harbinger of bad luck so cant believe things actually went okay-ish considering im not a competitive applicant
₊˚⊹♡.𖥔 ݁ Demographics
₊˚⊹♡.𖥔 ݁ Intended Major(s): Media Production / Film and Television Production / Communications / Media Studies
₊˚⊹♡.𖥔 ݁Academics
₊˚⊹♡.𖥔 ݁ Standardized Testing
₊˚⊹♡.𖥔 ݁ Extracurriculars/Activities:
i didnt plan my extracurriculars in high school i sure did a lot and most of them were scattered out HAHA. jack of all trades, master of none moments. i tried to include mostly my media and writing related activities. aside from the ones i listed on my common app, i was immersed in a lot of social justice and political advocacy works + other sports :)
₊˚⊹♡.𖥔 ݁ Awards/Honors
₊˚⊹♡.𖥔 ݁ Essay
₊˚⊹♡.𖥔 ݁ LORs
I did not read the letters but im basing it on how much they like me as a student. I chose these teachers because I got high grades in their subjects and they got PhDs.
₊˚⊹♡.𖥔 ݁ Interviewss- I got none and I was too busy to go for optional interviews. I really did not display any demonstrated interest.
₊˚⊹♡.𖥔 ݁ D*ecisionss *(ALL REGULAR DECISION, actually I filed my international applications late like 2-3 weeks after the deadlines because I was in a depressive episode last January)
ACCEPTANCES
WAITLISTS
REJECTED
₊˚⊹♡.𖥔 ݁Reflection
well that was krazy HAHA. ik many people here showcase ivies and T20s and im not that remarkable with my t40s to t100s but i'd like to think its not that shabby for an unknown international from a third world country. my biggest regret is not applying for NYU, its my dream school but again considering my depressive episode from November to January I wasnt able to file my application on time. its a miracle that universities still accept late applications and im grateful for all that I have and received. If i could turn back time I wish I was a little bit stronger and more stable to have been able to apply for NYU, my common app essay about my favorite author was actually an alumni from NYU :")
but we carry the burdens of choice under the merits of luck; even with merit scholarships, I cant afford any of the international schools I was accepted to. more likely i'll have to attend the top university in my country. but i dont want to give up man i'll still try to appeal for financial aid and if that wont work I'll apply for transfer during my sophomore year to ivies and top LACs that give full financial aid to international transfers. the odds are low but never 0 and no harm in trying !! see you all again next year for my transfer results :]
submitted by kainike to collegeresults [link] [comments]


2024.05.19 02:45 The_Brand94 RIGL Thesis 5/18/2024

~RIGL Thesis – 5/18/2024~
Outstanding Shares 175M
131 Institutional Holders
111,129,461 Total Shares Held
63.36% Institutional Ownership
Total Cash on Hand 3/31/2024 = $49.6M
Total Debt: $101.5M
Cash Burn Approximate = $8M per quarter (6 quarters of cash without any increases in revenue)
Q12023 REV = $26M
Q22023 REV = $26.8M
Q32023 REV = $28.1M
Q42023 REV = $35.8M
Q12024 REV = $29.5M (Decline from Q4 likely from end of year versus new-year tracking of Rx and shipments of drugs, resetting of Copays)
Most Recent EPS -$0.05 per share
May 22, 2024 - Vote on S will take place, caution
~Statistics Applicable To Thesis~
333.3 million US Population (2022)
8,109,679,892 Global Population (2024)
~Drugs On Market~
~Tavalisse – Treatment for ITP, FDA Approved April 17, 2018~
~What is ITP?~
Immune thrombocytopenia (ITP) is an illness that can lead to bruising and bleeding. Low levels of the cells that help blood clot, also known as platelets, most often cause the bleeding.
Once known as idiopathic thrombocytopenic purpura, ITP can cause purple bruises. It also can cause tiny reddish-purple dots on the skin that look like a rash.
Children can get ITP after a virus. They most often get better without treatment. In adults, the illness often lasts months or years. People with ITP who aren't bleeding and whose platelet count isn't too low might not need treatment. For worse symptoms, treatment might include medicines to raise platelet count or surgery to remove the spleen. Immune thrombocytopenia (ITP) - Symptoms and causes - Mayo Clinic
~What is Tavalisse?~
TAVALISSE is a prescription medication used to treat adults with low platelet counts due to chronic immune thrombocytopenia (ITP) when a prior treatment for ITP has not worked well enough. It is not known if TAVALISSE is safe and effective in children.
The cost for Tavalisse oral tablet 100 mg is around $15,404 for a supply of 60 tablets, depending on the pharmacy you visit. Quoted prices are for cash-paying customers and are not valid with insurance plans. This price guide is based on using the Drugs.com discount card which is accepted at most U.S. pharmacies.
Tavalisse Prices, Coupons, Copay & Patient Assistance - Drugs.com
TAVALISSE IS AN ORAL MEDICATION TAKEN TWICE DAILY WITH OR WITHOUT FOOD1
A 12-week evaluation period is recommended
60 tablets = 1 month supply, evaluation period = 3 months, Cost for 3 months = $46,212 Cash, assuming cheaper through wholesale, insurance, discount cards, etc.
Dosing TAVALISSE® (fostamatinib disodium hexahydrate) tablets (tavalissehcp.com)
~Addressable Market~
“Our findings suggest that nearly 20,000 children and adults are newly diagnosed with ITP each year in the US, substantially higher than previously reported. Among patients requiring formal medical care, the economic burden during the first 12 months following diagnosis is high, with estimated US expenditures totaling over $400 million.”
Primary immune thrombocytopenia in US clinical practice: incidence and healthcare burden in first 12 months following diagnosis - PubMed (nih.gov)
The estimated prevalence of ITP in the United States is 9.5 per 100,000 people, with a global prevalence of over 200,000 people at any given time [1].
Immune thrombocytopenia. [ Oct; 2022 ]. 2022. https://rarediseases.org/rare-diseases/immune-thrombocytopenia
~Author Calculations/Estimates~
ITP estimated cases based on measured statistics 31,635 cases a year in the US and 770,355 cases globally each year.
~Rezlidhia – R Acute Myeloid Leukemia, FDA Approved December, 22, 2022~
~What is Relapsed or Refractory Acute Myeloid Leukemia?~
Relapsed, or recurrent, acute myeloid leukemia (AML) means the leukemia has come back after treatment and remission.
Refractory AML means the leukemia did not respond to treatment. Complete remission has not been reached because the chemotherapy drugs did not kill enough leukemia cells.
Both relapsed and refractory AML need more treatment to reach complete remission.
Your healthcare team will suggest treatments based on your needs and work with you to develop a treatment plan. Some factors considered for your treatment include:
your age
your health
how long the leukemia was in remission
treatments you had before
where the leukemia comes back
Treatment options usually include chemotherapy and a stem cell transplant if possible. Targeted therapy may also be used.
Treatments for relapsed or refractory acute myeloid leukemia Canadian Cancer Society
~What is IDH1?~
Somatic mutations in isocitrate dehydrogenase (IDH) genes occur frequently in adult Acute myeloid leukemia (AML) and less commonly in pediatric AML… Enhanced genomic and epigenomic profiling of acute myeloid leukemia (AML) has led to identification of recurrent mutations that are prognostic and are candidates for targeted therapy. Somatic mutations in isocitrate dehydrogenase (IDH) genes, IDH1 and IDH2, occur in ∼6% to 16% and ∼8% to 19% of adult patients with AML, respectively.1-5 In pediatric AML, IDH mutations are rare, occurring in <4% of patients.6-11
Characteristics and prognostic impact of IDH mutations in AML: a COG, SWOG, and ECOG analysis Blood Advances American Society of Hematology (ashpublications.org)
~What is Rezlidhia?~
REZLIDHIA is a prescription medicine used to treat adults with acute myeloid leukemia (AML) with an isocitrate dehydrogenase-1 (IDH1) mutation when the disease has come back or has not improved after previous treatment(s).
Targeted Treatment REZLIDHIA® (olutasidenib) capsules
The cost for Rezlidhia oral capsule 150 mg is around $17,468 for a supply of 30 capsules, depending on the pharmacy you visit. Quoted prices are for cash-paying customers and are not valid with insurance plans. This price guide is based on using the Drugs.com discount card which is accepted at most U.S. pharmacies.
Rezlidhia Prices, Coupons, Copay & Patient Assistance - Drugs.com%20is%20a%20member,on%20the%20pharmacy%20you%20visit.)
~Addressable Market~
The annual incidence of new cases in both men and women is approximately 4.3 per 100,000 population, totaling over 20,000 cases per year in the United States alone.[13] The median age at the time of diagnosis is about 68, with a higher prevalence observed among non-Hispanic Whites. Furthermore, males exhibit a higher incidence compared to females, with a ratio of 5:3.
Acute Myeloid Leukemia - StatPearls - NCBI Bookshelf (nih.gov)
~Author Calculations/Estimates~
Cases of AML with IDH1 would be 11% based on the median of statistics above (6% to 16%) leaving approximately 1500 to 2000 cases a year in the US. Appling the same calculations to world population would amount to approximately 38,500 cases a year globally.
~Gavreto – Treats RET+ Non-Small Cell Lung Cancer In Adults and RET+ Thyroid Cancer in Kids and Adults, FDA Approved August 9, 2023~
For the sake of common ground, I am going to assume these types of cancers do not need to be elaborated on as we all likely have a basic understanding of what they are. The medical conditions treated by Tavalisse and Rezlidhia I felt needed a more in-depth explanation because they are not common. I will elaborate on RET+ a little later in this writing.
~What is Gavreto?~
GAVRETO is an oral once daily prescription medicine used to treat certain cancers caused by abnormal rearranged during transfection ~(RET+)~ genes in:
Adults with non-small cell lung cancer (NSCLC) that has spread
Adults and children 12 years of age and older with advanced thyroid cancer or thyroid cancer that has spread who require a medicine by mouth or injection (systemic therapy) and who have received radioactive iodine and it did not work or is no longer working*
It is not known if GAVRETO is safe and effective when used to treat cancers caused by abnormal RET genes in children for the treatment of NSCLC or in children younger than 12 years of age for the treatment of thyroid cancer.
Home GAVRETO® (pralsetinib)
The cost for Gavreto oral capsule 100 mg is around $11,745 for a supply of 60 capsules, depending on the pharmacy you visit. Quoted prices are for cash-paying customers and are not valid with insurance plans. This price guide is based on using the Drugs.com discount card which is accepted at most U.S. pharmacies.
The recommended dosage for adults and children 12 and over is 400mg orally once daily. Each capsule is 100mg, which means you will take 4 capsules. Gavreto should be taken on an empty stomach, at least 1 hour before or 2 hours after a meal.
Gavreto Prices, Coupons, Copay & Patient Assistance - Drugs.com
~What is Rearranged During Transfection Positive (RET+)?~
RET-positive cancer is caused by a mutation or abnormal re-arrangement of the RET gene. It occurs most commonly in lung cancer and several types of inherited and sporadic thyroid cancers. RET alterations also occur in an estimated 1-2% of multiple other cancers, including ovarian, pancreatic, salivary, breast, and colorectal cancers.
RETpositive Empowering Patients and Driving Research
Rearranged during transfection (RET) rearrangements were first identified as oncogenic drivers in NSCLC in 2012. The proportion of patients with NSCLC who have RET rearrangements (ie, fusion-positive disease) is approximately 1%-2%.
RET Fusion-Positive Non-small Cell Lung Cancer: The Evolving Treatment Landscape The Oncologist Oxford Academic (oup.com)
RET alterations occur most commonly in lung cancer (non-small cell lung cancer (NSCLC)) and the number of new cases diagnosed each year is considerable, accounting for approximately 37,500 [IG1] cases worldwide and 4,000 cases in the US (2% of NSCLC) (2,3). RET alterations are also common in several types of inherited and sporadic thyroid cancers and can occur in other types of cancers like ovarian, breast, pancreatic, and colorectal cancers, among others (4-8) adding >110,000 cases yearly worldwide (9).
What is RET Positive Lung Cancer? - The Happy Lungs Project
(2) Although medullary thyroid carcinoma represents 5-10% of all thyroid cancers, activating RET gene abnormalities occur in over 90% of hereditary and approximately 40%-60% of sporadic medullary thyroid carcinoma cases.
Patients – RETpositive%20Although%20medullary%20thyroid%20carcinoma,sporadic%20medullary%20thyroid%20carcinoma%20cases.)
~Prevalence of Non-Small Cell Lung Cancer~
Most lung cancer statistics include both small cell lung cancer (SCLC) and non-small cell lung cancer (NSCLC). In general, about 10% to 15% of all lung cancers are SCLC, and about 80% to 85% are NSCLC.
Lung cancer (both small cell and non-small cell) is the second most common cancer in both men and women in the United States (not counting skin cancer). In men, prostate cancer is more common, while breast cancer is more common in women.
The American Cancer Society’s estimates for lung cancer in the US for 2024 are:
About 234,580 new cases of lung cancer (116,310 in men and 118,270 in women)
About 125,070 deaths from lung cancer (65,790 in men and 59,280 in women)
Lung Cancer Statistics How Common is Lung Cancer? American Cancer Society
Worldwide, an estimated 2,206,771 people were diagnosed with lung cancer in 2020. These statistics include both small cell lung cancer and NSCLC.
Lung Cancer - Non-Small Cell: Statistics Cancer.Net
~Author Calculations/Estimates~
Approximately 187,664 cases of NSCLC in the US based on an 80% factor.
Approximately 1,765,416 cases of NSCLC worldwide based on an 80% factor.
~Prevalence of Thyroid Cancer~
Rate of New Cases and Deaths per 100,000: The rate of new cases of thyroid cancer was 13.5 per 100,000 men and women per year. The death rate was 0.5 per 100,000 men and women per year. These rates are age-adjusted and based on 2017–2021 cases and 2018–2022 deaths.
Lifetime Risk of Developing Cancer: Approximately 1.2 percent of men and women will be diagnosed with thyroid cancer at some point during their lifetime, based on 2017–2019 data. Lifetime risk based on data through 2022 will available soon.
Prevalence of This Cancer: In 2021, there were an estimated 979,295 people living with thyroid cancer in the United States.
Thyroid Cancer — Cancer Stat Facts
About 44,020 new cases of thyroid cancer (12,500 in men and 31,520 in women)
About 2,170 deaths from thyroid cancer (990 in men and 1,180 in women)
Thyroid cancer is often diagnosed at a younger age than most other adult cancers. The average age when a person is diagnosed with thyroid cancer is 51.
This cancer is about 3 times more common in women than in men. It is about 40% to 50% less common in Black people than in any other racial or ethnic group.
Key Statistics for Thyroid Cancer American Cancer Society)
Addressable Market
Given Gavreto’s dual treatment capacity, the total amount of potential patients with NSCLC with RET+ indications would be approximately 2,800 cases in the US and approximately 26,500 cases worldwide each year using a factor of 1.5% of total NSCLC cases. The total amount of treatable cases for Thyroid Cancer would be approximately 650 in the US and 16,500 cases worldwide respectively each year applying the same 1.5% RET+ percentage rate. DOUBLE CHECK MATH…
~Rigel Pharmaceuticals Pipeline~
~IRAK/4 – Clinical Trials~
Rigel’s investigational candidate, R289, is an oral, potent and selective inhibitor of interleukin receptor-associated kinases 1 and 4 (IRAK1/4).
Toll like receptors (TLRs) and the interleukin 1 receptor family (IL-1Rs) play a critical role in the innate immune response and dysregulation of these pathways can lead to a variety of inflammatory conditions such as psoriasis, rheumatoid arthritis, and inflammatory bowel disease. Chronic stimulation of both receptor systems has also been implicated in causing a pro-inflammatory bone marrow environment leading to persistent cytopenias in lower-risk myelodysplastic syndrome (LR-MDS) patients1.
R835 is a selective dual inhibitor of IRAK1/4 that blocks TLR4 and IL-1R-dependent systemic cytokine release. In preclinical studies, R835 demonstrated activity in multiple animal models of inflammatory disease2,3 and showed that dual inhibition of IRAK1 and IRAK4 provided more complete suppression of inflammatory cytokines when compared to an IRAK4-selective inhibitor4.
Development of R289:
In a Phase 1 clinical trial, R835 was well tolerated and inhibited LPS-induced inflammatory cytokine production in healthy volunteers, demonstrating proof-of-mechanism.5 Phase 1 clinical studies of R289 (an oral prodrug that is rapidly converted to R835 in the gut) are also complete.
A Phase 1b open-label, multicenter trial of R289 in patients with relapsed/refractory lower-risk MDS is currently enrolling (NCT05308264). The primary endpoint for this trial is safety with key secondary endpoints including preliminary efficacy and evaluation of pharmacokinetic properties.
~Bemcentinib – Bergenbio Partnership~
In June 2011, Rigel entered into an exclusive, worldwide research, development and commercialization agreement with BerGenBio for its investigational AXL receptor tyrosine kinase (AXL) inhibitor, R428 (now referred to as bemcentinib).
Bemcentinib is a potent, selective and orally bioavailable AXL inhibitor and the furthest along in clinical trials. In preclinical studies, bemcentinib was shown to have an effect as a single agent therapeutic in the prevention and reversal of acquired resistance to standard of care cytotoxics and targeted therapies and may also slow or prevent tumor metastasis.
Rigel received an upfront payment and is eligible for milestone payments and potential sublicensing revenue, as well as tiered royalty payments on any future net sales of products emerging from the collaboration.
~R552 Systemic – Eli Lilly Partnership~
Rigel’s investigational candidates are oral, potent and selective inhibitors of receptor-interacting serine/threonine-protein kinase 1 (RIPK1).
RIPK1 is a critical signaling protein implicated in a broad range of key inflammatory cellular processes including necroptosis, a type of regulated cell death, and cytokine production. In necroptosis, cells rupture leading to the dispersion of cell contents, which can trigger an immune response and enhance inflammation. RIPK1 inhibition has therapeutic potential in treating autoimmune, inflammatory, and neurodegenerative disorders.
Rigel’s RIPK1 inhibitor program includes R552, a systemic molecule being developed for the treatment of autoimmune and inflammatory disorders, and brain penetrating RIPK1 inhibitors for central nervous system (CNS) diseases. In preclinical studies, R552 demonstrated prevention of joint and skin inflammation in a RIPK1-mediated murine model of inflammation and tissue damage.
Development of R552:
In Q2 2023, the initial Phase 2a trial (NCT05848258) in moderately to severely active rheumatoid arthritis (RA) was initiated by partner Eli Lilly.
Development CNS-penetrating RIPK1 inhibitors:
Currently in preclinical studies.
~Milademetan – Daiichi Sankyo Partnership~
Rigel has a long-standing collaboration with Daiichi-Sankyo for developing murine double minute 2 (MDM2) protein inhibitors in cancer, which were discovered in Rigel’s laboratories.
Preliminary safety and efficacy data from an early Phase 1 study of milademetan (formerly DS-3032), an oral selective MDM2 inhibitor, in hematological malignancies suggests that it may be a promising potential treatment for oncology indications.
Rigel received an upfront payment and is eligible for milestone payments, as well as tiered royalty payments on any future net sales of any products emerging from the collaboration.
~Rxxx (CNS Penetrant) – Eli Lilly Partnership~
Rigel’s investigational candidates are oral, potent and selective inhibitors of receptor-interacting serine/threonine-protein kinase 1 (RIPK1).
RIPK1 is a critical signaling protein implicated in a broad range of key inflammatory cellular processes including necroptosis, a type of regulated cell death, and cytokine production. In necroptosis, cells rupture leading to the dispersion of cell contents, which can trigger an immune response and enhance inflammation. RIPK1 inhibition has therapeutic potential in treating autoimmune, inflammatory, and neurodegenerative disorders.
Rigel’s RIPK1 inhibitor program includes R552, a systemic molecule being developed for the treatment of autoimmune and inflammatory disorders, and brain penetrating RIPK1 inhibitors for central nervous system (CNS) diseases. In preclinical studies, R552 demonstrated prevention of joint and skin inflammation in a RIPK1-mediated murine model of inflammation and tissue damage.
Development of R552:
In Q2 2023, the initial Phase 2a trial (NCT05848258) in moderately to severely active rheumatoid arthritis (RA) was initiated by partner Eli Lilly.
Development CNS-penetrating RIPK1 inhibitors:
Currently in preclinical studies. Pipeline :: Rigel Pharmaceuticals, Inc. (RIGL)
~Summary and Prediction~
The current share price of sub $1 does not feel justified. I would anticipate financial breakeven by the end of 2024 or potentially in Q1 or Q2 of 2025. The robust pipeline, progress, and expected revenue growth are enough to justify a much higher valuation. The debt load is manageable, but the potential for S is concerning. I believe that the S is not necessary and revenue growth and progress should speak for itself. I am not as bullish as the analysts at HC Wainright for a $15 PT, but the valuation should be at least 3x to 5x from the current value. This thesis does not highlight the patents surrounding their drugs either which some extend into 2035 and beyond. Perhaps what Wall Street is discounting is the fact that most of the drugs are very niche. However, the currently available drugs have an addressable market, albeit less universal than some, but you should value it in the sense of multiple facets (a 1000 headed snake is the phrase I wanted to use). I believe the company should be valued with specialty drugs in mind which would command a higher PE ratio. At the current day and time of writing, the value should be at least $1.50 to $1.75 ~at a minimum~ with a 12 month price target of $3 to $5+. I will be looking for continued revenue growth in each quarter this year and realization of revenue from Gavreto in Q2 or Q3 this year. The partnerships should not be discounted either and the current share price if it lingers here perhaps may attract a merger or acquisition. I initially began the research thinking that perhaps the drugs were too niche, but given the multiple drugs they are working with, I believe their revenue sources will continue to grow if you do not focus on one particular drug as the main performer. With the most recent inflation report being cooler than expected, I would suspect larger funds and institutions will be circling back to riskier assets.
submitted by The_Brand94 to u/The_Brand94 [link] [comments]


2024.05.19 02:37 United-Ad9475 Orientation Question

Today is my 2nd day of orientation. I worked on online training from 8AM-12PM. When will I start on the sales floor? When will I meet my DS/ managers? Will I get store walk tour or something? How many more days of online training?
submitted by United-Ad9475 to Lowes [link] [comments]


2024.05.19 02:04 ParkersCuddles My dr told the chemist not to dispense my T

Need advice pls, Also TW possibly ahead. Had a real Shit day today.

Started off aight. Had a dream I was spiderman, and this time didn’t run outta my web fluid mid-swing 🤣😭

I had a shower was all good but after that. Shit only went down hill. (In the shit way) So I showered, and got ready to go get my T shot. Because I’m due today. (This was on Monday and it’s now Thursday 😭) So I got ready all except my shoes and grabbing the actual box of T to take with me. Went to look for the box. It’s gone.

(For context my mum had been in my room, had admitted to “cleaning up the floor a little and taking out the rubbish”)

Right so ideally id like to assume my mum hasn’t taken it. Because I’d like to assume my mum wouldn’t push her opinions of my decisions on me like that. So I’m just gonna say it was on the floor and she put it in the medicine cabinet or in the bathroom with my other ointments n meds n stuff (or where my morning meds are next to the bench.) Not in any of those places. Right so I thought right I’ll call mum. Coz she’d probably just moved it and hadn’t known that id put it in a very specific location for a very SPECIFIC REASON. Call her. “Nah idk I havnt seen it” Right. Then I’m just fuckin blind coz I’m rushing and looking for it. It’s gotta be here somewhere. Aggressive loud and panicked rummaging Bout 20 mins goes past. (Queue the bin/recycling truck noises this will be useful later I promise) I call her again. “Mum can you please promise me you didn’t see it and that you didn’t take it.” “deadname stop calling me I’m at work. I’ll talk to you later” Right she didn’t promise. She was either actually stressed at work or was trying to get me to stop talking about it. So I go looking in the places she used to hide my phone / iPad / DS / Computer / whatever when she took things off me. Not anywhere. Right now I think back to the last time I saw it or something similar and brushed my eyes over it. Last I KNOW I saw it. It was in the chemist warehouse (Australian chemist place) bag on the floor beside my bed. Right well she cleared the floor. So I’ll go look in all the places she stuffed shit in while I wasn’t here. Not in the backpack, not on the top bunk of my bed, not under my bed. Not in any drawers. Ok well my appointment to get my injection is in 30 mins and I’ve been searching for 30mind stressed asf coz I needa get on the bus. So let’s see if I can move that appointment. Moved the appointment back 2 hours. Right now I got 2.5h to find it. Now I have a very thorough look for it in my room in all the places that have been TOUCHED recently. Incase I’m just stupid and put it there to HIDE it. Coz doggy brain (and trauma) say “hide precious thing so nobody take. Coz precious thing good and need to keep safe.” Ok. I look in those places. Not there. Right well she cleared out the RUBBISH and a plastic chemist warehouse bag with a box and a receipt could be “rubbish” right well I took out the recycling yesturday and saw a blue and white somethin in the recycling maybe it’s in the recycling bin. …. •-• the bins 2 houses up. Has already been. Fook me dead. Right well literally EVERY OPTION of me getting the box I collected last week at the pharmacy hasn’t worked. Aight well what’re my options? Call the hospital see if they can get me an emergency script. Nope they said call ur GP. I call my GP, ask them what to do coz I havnt had my T shot, and they have literal proof coz I booked the injection with them. Had havnt had it…..

so I call em up. They said “yeah come in we’ll see what we can do” they get me a script. I’m brilliant I could KISS the gp rn :D!!

Get to the chemist. They make me wait 45mins. “Sorry we gotta call the dr coz he didn’t put the interval of how often you take this” Aight sure I’ll just wait. … Sorry you already have a script for this, and you picked it up the other day, so we can’t give it to you. Aight. Well I literally got the second proscription, so that I could get a new bottle… because I’ve LOST / HAD IT TAKEN FROM ME / IT HAD BEEN THROWN AWAY BY ACCIDENT That’s why u got the second proscription paper thingy. “Yeah nah I can’t do that” “Tf you mean nu-uh.” “Well we called ur GP on the script.

Told him (coz why wouldn’t you) you picked it up the other day and he said not to dispense it”

Dawggggg I literally came into the fucking medical centre told y’all the situation and u gave me the script not even 20 mother fucking minutes ago. Aight can I take my script back? Yeah. Aight well I still have the bit of paper of me needing my T. (Mind you, he didn’t put the fucking concession on it. So would’ve costed me 150$ instead of S E V E N which is how much u usually pay.) I call the medical centre I was literally JUST AT 20 mins ago “hey yeah he just told the chemist NOT to give it to me after I literally just left to come get it.” “Aight brb I’ll go talk to him” … “Yeah nah sorry can’t do anything…” “Aight well what am I gonna do then?”

“Idk hangs up

WELL FUCK ME SIDEWAYS (don’t actually but it’s too late coz my days already FUCKED ME SO WHY NOT JOIN IN )

Aight well what are my other options. I’ll ring my endo see if he can call the pharmacy and tell them to gimme my fuckin boy juice. Aight he’s not in today. Right well reception sent him an email. He’s on leave for another fuckin 3 weeks. Right. Only other option. Is to go to another pharmacy. And try use this script which chemist warehouse already scribbled all over.!!!! See if they’ll give it to me. Priceline (another pharmacy) doesn’t have any. Right try the other one. They’re confused as to why they’d scribbled on it and DIDNT give it to me. I explain my situation. They said “also btw how much you usually pay for this..?” “Like 7 bucks..” “He hasn’t put the concession on this. And he can’t cos he’s not a specialist. And I’d have to ring him to ask if I can give this to you.” “Right then nvm I’ll try something else. Coz he’s just gonna tell you not to give it to me :)” Ok well I’m fucked now. It’s not at home. They won’t give it to me. I’ve tried every pharmacy in the area and they’ve all told me to get fucked. Right idk what else to do so I’ll go to safe haven (where mentally ill people go when they’re having / about to have a crisis. And need help coz they’re feeling unstable.) I go there. Chat to the chick there she suggested I try the gender centre or 20ten or whatever. Call the gender centre. They gimme a list of numbers to try. Tried all of em. One calls me back and says to call MY endo’s place coz SURELY he’s not the only endo there. So I do. They shut THREE MINUTES AGO. (4.03pm) :))) Aight guess that’s all I can fuckin DO FOR TODAY :))) So now I’m sitting here (bbq sauce in my tiddies) / ref And idk what to do.
OH and coz the day wasn’t COOKED enough.

The buses I signed by waving for a solid 8 seconds. Both changed lanes (to make the next turn in the route) AND DROVE PAST ME!!!!! So I WALKED to safe haven!!!!

Anyways. It’s Now Thursday I have some more info. Still have the problem UNSOLVED.

Called the endo. They said they’d see if they can get the other endo to call the chemist.

Mum didn’t chuck it out on purpose but thinks I could’ve been thrown away by accident when she was cleaning (it has to have been coz it’s not in my room or any-bloody-where else.

Ive called the endo up multiple times. I’ve called my GP and he just said “you could’ve sold it so we can’t get you another one” BUT WHY WOULD I SELL IT?! W h Y?!! And it has MY NAME ON IT. NOBODYS GONNA GIVE SOMEONE AN INJECTION THAT DOESNT HAVE THEIR NAME ON IT🤌🏻 bro the fuck just gimme my boy juice 😭😭😭

So I’ve had a pretty fucked week stressing over this so I’d appreciate any ideas anyone has on how I can get my T 😭

I live in Australia so we gotta abide by those laws with giving meds n shit but if u know a way around it… or somethin pls comment at lmk I really needed this like a hole in the head 😭😭😭
submitted by ParkersCuddles to trans [link] [comments]


2024.05.19 01:18 Complex_Order7708 Lost Fortress triple Boss

Im in the lost fortress and im stuck with the 3 bosses and i cant kill them even with the NPC its still to hard i am at my 42 try. Im level 54 have a +5 sword and ds2 is my first ds. So pls help me and btw idk how the online stuff works im mean i have the stone to get people in my world but idk the rest
Pls help.
submitted by Complex_Order7708 to DarkSouls2 [link] [comments]


2024.05.19 00:27 sridges94 AMs: What’s it like at a DS?

Hello,
I just want to hear what it’s like working at a DS and how the leadership org is structured there.
I’m an L5 AM at an AR Sortable FC. I currently run Sort and Pack for AFE and have almost 90 associates on my roster. However, my area usually hosts up to 200 associates depending on volume, number of flex AAs, and labor share AAs.
I know it’s a much smaller building with a way smaller headcount.
My site is currently 40 miles each way, but it’s the only AR site in the area. I have no interest working at a Sortation Center or any other type of site, other than an IXD. My wife wants me to look into transferring closer and to something with a better schedule, because I’m on 12 hour night shifts, but I don’t want to slow down my growth.
submitted by sridges94 to AmazonFC [link] [comments]


2024.05.18 22:33 CatsCookiesBooks ADA Accommodations for Disabilities in PhD Programs

I did a search for this in this subreddit and didn’t find anything, so asking here. I am applying to clinical and health psychology PhDs this fall. I have several chronic illnesses and currently have ADA accommodations at work for 100% telework and flex schedule/sick leave for appointments and flare ups. The telework is really important and literally the only reason I can work full-time, but I also have anywhere from 2-5 medical appointments each week. My health is really unpredictable, and I get fatigued and rundown and sick very easily. For all these reasons, I’m really nervous about being able to physically handle a PhD program, but I really want to do it if possible. I don’t want to have to settle with my career just because my body has limitations that are out of my control.
I’ve heard the accommodations process for grad school in particular can be very difficult, and also very dependent on the program and faculty. In particular, I expect that a request to attend classes virtually will be difficult. And my experience at a lab at a university has really disappointed me, as my advisor liked to talk a lot about DEI but was not actually willing to accommodate my disability.
So would anyone be willing to share their experiences with requesting accommodations or how they managed their program with a serious disability? Did you find faculty willing to accommodate you? Was the process difficult?
Thanks in advance!
submitted by CatsCookiesBooks to ClinicalPsychology [link] [comments]


2024.05.18 22:33 astralrocker2001 It's truly adorable when one DARPA puppet front man (Shelon Musk) calls out another DARPA puppet front man (Fauci) for creating COVID-19, instead of calling out the Luciferian Rothschild-Rockefeller NWO/DARPA his boss for hitting us with COVID-19. Elon is no. 1 DARPA/DoD contractor, worth $200B haha

It's truly adorable when one DARPA puppet front man (Shelon Musk) calls out another DARPA puppet front man (Fauci) for creating COVID-19, instead of calling out the Luciferian Rothschild-Rockefeller NWO/DARPA his boss for hitting us with COVID-19. Elon is no. 1 DARPA/DoD contractor, worth $200B haha submitted by astralrocker2001 to bestconspiracymemes [link] [comments]


2024.05.18 22:32 JasmineGlisten_ How could I make myself eligible for engineering?

How could I make myself qualified for engineering as an international student?
How could I make myself a qualified engineer without being well prepared?
I’m not sure if this is the best tag, but I’m genuinely curious about how could I make myself more confident with engineering work.
My bg is that I’m international student from China and my whole family support my study in us. Currently I’m a sophomore studying in UWMadison and majoring in CompE and DS. I have a GPA of 3.7, and I was trying to transfer to a higher rank uni.
I had a bad start because I started studying STEM in high school and my bg was not as good as my peers. I was lucky enough to land an IT internship this summer but was rejected almost every school I applied for transfer (Umich etc and I don’t feel like I’m good enough to get into USC and UTAustin).
So my experience in college is that I feel it’s hard to study engineering and I’m almost paying all my energy into studying to just barely have a 3.7. I did have a few Bs and BCs and the only thing I did in college is work as a technician in school department. I took a few IT related certifications and the only advantage I have is probably over 90 credits now…
I’m wondering if anyone could give me some advice abt how to improve myself cause my goal is to stay here and get a job. I’m not waiting for a 100k job, I just want to support me and my family and have a better life. However I feel exhausted studying and working in college; I don’t have trouble forcing myself work or study but I feel I’m lacking of energy and the only thing that supports me is the far-away dream of having a good paying job.
To be more specific I don’t know how to start. I don’t know the competitions my friends engaged in high school, and I don’t know the stuff that my friends already learnt before attending college. The first year here is still a nightmare for me that I slept only 3-4 hours per day to catch up. I self-studied AP physics but realized that after began to studying for engineering classes I had 0 advantages both in language aspects and studying aspects. Also I met a few bad teammates which brought me those B/BC in my grade…
I feel like I’m too late to learn engineering and I am afraid I’m not eligible for being a successful engineer in the future. How could I compete with others in the job market with such late start and 0 connections? I even don’t know how to make connections. This made me have very bad depression and anxiety and I began to take high dose medication. With medication I’m able to act normally but I feel like I’m just different from normal people. I’m also worried that since I don’t have much experiences and money, I have 0 chances to start over. I love studying engineering but I never feel like I should enter this field.
Pls help me, I’m open to all suggestions. I don’t want to give up. Thanks for all the suggestions in advance.
submitted by JasmineGlisten_ to EngineeringStudents [link] [comments]


2024.05.18 22:28 Alarmed_Goat4986 Please help

How could I make myself a qualified engineer without being well prepared?
I’m not sure if this is the best tag, but I’m genuinely curious about how could I make myself more confident with engineering work.
My bg is that I’m international student from China and my whole family support my study in us. Currently I’m a sophomore studying in UWMadison and majoring in CompE and DS. I have a GPA of 3.7, and I was trying to transfer to a higher rank uni.
I had a bad start because I started studying STEM in high school and my bg was not as good as my peers. I was lucky enough to land an IT internship this summer but was rejected almost every school I applied for transfer (Umich etc and I don’t feel like I’m good enough to get into USC and UTAustin).
So my experience in college is that I feel it’s hard to study engineering and I’m almost paying all my energy into studying to just barely have a 3.7. I did have a few Bs and BCs and the only thing I did in college is work as a technician in school department. I took a few IT related certifications and the only advantage I have is probably over 90 credits now…
I’m wondering if anyone could give me some advice abt how to improve myself cause my goal is to stay here and get a job. I’m not waiting for a 100k job, I just want to support me and my family and have a better life. However I feel exhausted studying and working in college; I don’t have trouble forcing myself work or study but I feel I’m lacking of energy and the only thing that supports me is the far-away dream of having a good paying job.
To be more specific I don’t know how to start. I don’t know the competitions my friends engaged in high school, and I don’t know the stuff that my friends already learnt before attending college. The first year here is still a nightmare for me that I slept only 3-4 hours per day to catch up. I self-studied AP physics but realized that after began to studying for engineering classes I had 0 advantages both in language aspects and studying aspects. Also I met a few bad teammates which brought me those B/BC in my grade…
I feel like I’m too late to learn engineering and I am afraid I’m not eligible for being a successful engineer in the future. How could I compete with others in the job market with such late start and 0 connections? I even don’t know how to make connections. This made me have very bad depression and anxiety and I began to take high dose medication. With medication I’m able to act normally but I feel like I’m just different from normal people. I’m also worried that since I don’t have much experiences and money, I have 0 chances to start over. I love studying engineering but I never feel like I should enter this field.
Pls help me, I’m open to all suggestions. I don’t want to give up. Thanks for all the suggestions in advance.
submitted by Alarmed_Goat4986 to EngineeringStudents [link] [comments]


2024.05.18 21:26 PocketPlayerHCR2 1.61 will SUCK

These 2 statements alone lead to a conclusion that this update has to go wrong. In the first one, Rhys states that they only want to make the game fun to play, and never think about what will happen to the leaderboards. And immediately we see the first problem, because how the heck can you not care about the leaderboards if you're making a racing game!? This game's all about competing for the top times, so why don't the devs care about what will happen to the top times? I genuinely have no idea.
The second message from Rhys says this update is not for casuals, but for hardcore players. But wait a second, didn't he also say that they want to make the game more fun and never think about world records? The thing is... Hardcore players are here for world records, and casuals just want to have fun. However this update is meant to be fun and for hardcore players, while the devs are aware the leaderboards will drastically change and casuals won't be able to master their vehicles.
This simply doesn't work. If you want to make an update for top players, you can't at the same time not care about their efforts put into records. Years of optimising and finding strategies are going to go to waste because of this update, and this is not a good thing. Titanium says more about this in his video, so go watch it if you need more explanation, in the meantime I'll just get to the next topic.
A common counter"argument" to this is: bUt ThEy CaN jUsT gEt ThEiR rEcOrDs BaCk!!!! They can, sure. The thing is that they will have to spend a lot of time on it. Hours of their grind are worth nothing now, and they will need to grind every record again. That's hundreds of hours worth of grind just to get all the ADVENTURE records to be good (there are like 300 of them, and you are not gonna get every single one in 20 minutes), and if you include time attack, it's suddenly thousands of hours of grinding. Just for the records to be decent.
To Fingersoft: (I also recommend reading the previous part of the post, not just this part) As I am sure you aren't willing to just not implement the update, I'm begging you for one thing: make a separate leaderboard for vehicles with and without the mastery upgrades, and also make vehicles that use them unable to get adventure stars. The leaderboard thing is quite obvious, this way the work players put into their records will still be worth it, and players with mastery upgrades will be able to enjoy them and make new crazy strategies. You might however not understand why adventure stars are such a big deal, so let me explain: some players spent hours on grinding them, just like world records, and once again their efforts would turn out to be worth nothing if you could have better grip, engine, acceleration or whatever, and also another part. Just take a look at the struggles of getting max stars in city (especially moonlander): while driving moonlander, you have to drive very precisely to have enough fuel, especially in the 9.2 - 9.6 section. If you could get that 10k in a few tries because of the new mastery upgrades, their struggles would be unnecessary to achieve maxed stars in this map, so please, make vehicles that use them unable to get adventure stars.
Don't get me wrong, I think that this update could be pretty fun and I'm quite excited to put wheelie boost on my buggy together with kangaroo, but the price we have to pay (which is thousands of hours of grinding, struggling and thinking of new strategies) is too big. So please, change this system a bit, before it's too late.
submitted by PocketPlayerHCR2 to HillClimbRacing [link] [comments]


2024.05.18 21:12 StockSong6126 Hinjew?

Lately my wife has been researching Hinduism and I've seen a few stories of Jews becoming Hindu and I was just wondering if anyone here knew anything about this. Yourself or someone you know? Any articles on this? My wife and I are Jewish and I am more religious and practicing then she. She has set her heart on Hinduism and it's been difficult to be honest. I've seen a few people say they make it work but I haven't seen a real in depth conversation about it. I understand that one believes in many g-ds and the other only one. I also understand that they are very similar in some ways. I'm just curious if anyone has every experienced anything like this and how your daily life is. Thank you.
submitted by StockSong6126 to Judaism [link] [comments]


2024.05.18 17:23 MerkurSchroeder NDD: Target Exo 03 (21g, 90% Tungsten)

NDD: Target Exo 03 (21g, 90% Tungsten)
I know a lot of you guys are very keen on the Target Exo series, so having made a first impression on the Exo 03 21g, I'm putting down some notes for you.
These are the first out of the series I'm holding in my hands and I'm surprised how rather specific they are for a budget roster, being used to some versatile Bolide shapes. The Exo 03 will always want to be played based around the large middle ring grip section which is where you'll find your traction.
Both slight ring cuts in the rear and front are rather slippy. I'd say the front is almost for decoration only whilst the back can give enough grip if you use the thumb, index, middle and ring finger along the barrel. In my opinion having less friction in the front can be an advantage for smooth groups, so I embrace it.
What the Target Exo 03 seem to scream for is more a middle or middle/front grip (thinking Joe Cullen/Gerwyn Price style) with at least thumb or index finger on the middle section and middle finger on the point, which will supposedly really shine using a Firepoint or DS fingergrip.
Sadly the market is currently wiped clean of any Swiss Points longer than 26mm complemented by sporadic offers with shipping time between one and three weeks or prices up to 20€. German Amazon have even canceled any offer of 40mm points.
I'll have to wait at least until next week for some silver 30mm Firepoints to arrive for at least 3€ less than I'd have had to pay for alternatively available 35mm DS incl. tax and shipping. I'm neither proud of the paid price nor my forecast of this scenario a few weeks ago came true.
With the ongoing hype around darts and Target products it was to be expected a still rather stable supply of Swiss Points would reach the same state we had with K-Flex that got back into circulation after a while. So nothing really to be worried about, except with the points there's no alternative and we might have to stock up on occasion.
However, neither I nor the woman who bought the Exo 03 as a surprise for me accidentally* after I had shown her the Exo 02 that would go great with the spare Storm Points I have, had planned to buy the Exo 03 at this moment. We just decided to keep them, now that I know I like these. (*I didn't expect she would buy them, so I wasn't precise enough for her to find a way through the mixed up Amazon offer of all three barrel shapes on the same page.)
The Target Exo 03 are very pragmatic in design which I can appreciate. For me the ring grooves wouldn't even have to be painted, but I'm happy to report the paint doesn't seem to reduce the medium grip level, like I've experienced on other darts and which is the reason some of you are stripping the color. The middle section isn't overly grippy though, which for me leads to a rather smooth release, but I've read some weren't as convinced.
It's a great entry level Swiss Point dart in my opinion, even though I'd like to point out I've bought all my Bolides discounted to the same 39,95€ that are asked for Exo darts regularly and you'd sure want to buy your preferred points on top. The supplied 26mm chrome points will work scuffed up, but as mentioned above I see more potential in finger grip points.
With quite some similarities to my Bolide 04 except for grip level and scallop I wanted some shorter points than the 40mm DS I play on those for comparison. In a perfect world I might have gone for 35mm Firepoints, that I wanted to try, but considering the 30mm I'll receive I provisionally equipped the Target Exo 03 with fairly used 30mm Storm Points.
At first I put some short No.2 K-Flex on the Target Exo 03, because I think the white goes very well with that barrel. Between throws I've changed to red short No.6 I had though, which are the same size like the supplied setup and seem to be the better speed.
Another great option I have just tested spontaneously (no picture included) are my beloved Harrows Retina Velos flights on short Supergrip Fusion stems like I play on some other darts. This is a great balance between speed and control.
With the huge initial demand we'll have to see if the Exo darts will get discounted soon as well, but if you're in need of some decent Swiss Point darts, the 03 will surely cater everything required for some satisfying play. They're just not extra grippy and this model may not suit every throw like explained.
Almost 40€ is still not a cheap dart, even for 90% Tungsten, but I guess in the Target world, which to me looks like an equivalent to Apple, it's rather affordable. I'm sure the other models find their purpose as well and so I'm especially looking forward to trying the Target Exo 02 either. Spoiler: They've just been in the mail, but I can't unbox them until tomorrow.
Have you been able to play any Target Exo yet and what's your opinion?
Have a nice weekend.
Cheers and happy darting! 🎯👍
submitted by MerkurSchroeder to Darts [link] [comments]


2024.05.18 15:35 Scapegoat24 It's probably a silly argument, but I need to vent

Hi, guys.
I need to vent. I try to ignore this and not react to it, but sometimes it's just overbearing. And I feel like a failure because I let this get to me when I could just ignore it. I could talk to a friend about this, but I feel it's always something so stupid and I am embarrassed! Not to mention, what they tell me is like "You should move out" and "If I were you, I wouldn't submit myself to it and I would just tell him everything" as if I was weak and had no boundaries. I feel judged and embarrassed. I have no conditions to move out even though I am older now (turning 30 yo) and work for myself.
I usually don't cry but this made me cry hard after the argument. Maybe because I had been having a good week and this escalated out of nowhere!
So, my godmother invited my parents to have lunch together this Saturday, she was going to throw a family party and invited our family to lunch. She did so on Thursday - not much anticipation, just the Portuguese way. My sibling was going out of town this weekend, and I was the only one who stayed. On Saturdays, my parents usually rent their office to a friend of my mom's who is a psychologist. It's at 1 PM but they usually open the door to her around 12:40/12:45 pm. So, they needed someone to open the door to her when she arrived, because they were going to the party!
When my nfather called me, he exposed the situation and he asked me in a way he'd be hoping that I said no (because he needed someone to open the door to the friend). He's usually really upset when we don't come to family things, especially when she's my godmother, but this time he just asked me "Do... Do you want to come?" lol It was obvious! I said no and that I already had plans - to be fair, I hadn't, I knew I had something on but wasn't sure what.
My godmother lives at a 1-hour distance from us, more or less. And usually, my parents go shopping first thing in the morning, which they did today as well. But they left the house around the same time they did on the other weekends (11 AM) and arrived home at 12:30 PM lol So, while helping them unpack the groceries, I asked what happened and told my mom (but my nfather listened and assumed it was foagainst him) that, if they were to leave and come back home this late, they should have just opened the door to the psychologist instead and asked her to come earlier, than asking me to readjust my plans.
And, Hell started. He came to the kitchen and said with such a bratty smile "Look, do a sacrifice for the poor infants of this world" and a bunch of other stuff lol I explained to him that I was doing them a favor and that I had changed my plans over this, so this wasn't fair, and - after he started throwing shit at me - that his attitude was wrong. I did the same thing he always does - he likes to say how other people should react and speak to his words - apologetically - instead of arguing (ex.: "You should just have said 'Sorry, dad, I was tired and couldn't do it, but I will do better next time'). So, I said something along the lines of "I'm cancelling my plans to do you a favor and it turns out it wouldn't have been needed in the first place. It would be okay if you told me 'I was late, X happened, I'm sorry'.
He started yelling about how I should be humbler, how he's the most humble person in this house (also yelling about how he helps everyone but no one helps him - fake -, how much he works and has two PhDs... lol See how humble he is!), on how I should be embarrassed before God and learn how to do sacrifices (to him, this was a sacrifice for God, not a favor for him), how I was a sinner, etc, etc. I couldn't hold my tongue and told him he was the least humble person and the most sinner person I've ever met and that he'd certainly go to Hell instead lol To this, he said God is at his side always.
He also accused me of charging him with that just because I was doing him a favor. I mean, if I asked someone for a favor but it turned out I had been troubling them when I could have done it myself, I would take the comment and apologize instead, or ignore him. But he took that as a criticism. And, when I told him to stop throwing shit at me, he said: "I am not shit, stop insulting me, you're shit!" lol And I said I wasn't insulting him, I was saying he was arguing shitty things and that it wasn't the same. He kept repeating that, so I said, "If you think otherwise, then okay, but it's on you"... and he was like "No, you called me shit, you insulted me, see? Here you have it, God just has heard you, hahaha".
I hate this religious shit and I don't believe him. He's becoming too focused on religion (he was always, to the point of saying "God punished you" whenever I fell as a child, but now he's more). When I was young, I used to cry and ask God how could God support someone like him who'd abuse me - my mother once told me my nfather had a gift, that he could speak to God and get responses lol. As a child, I believed him and got sad over it.
But I learned better after a while, and understood he was just justifying his own inner thoughts and his attitudes as if they were God's will, and not his'. I don't even know why he thinks this affects me, I couldn't care less about religion tbh. I mean, I am catholic and I do pray at night, but it's for myself, I'm very far away from the beliefs and traditions most believers have. And for sure I don't act thinking about what is good or bad in the eyes of God lol
So, at a certain point, I told him that he should stop this and apologize instead, or else he'd have to open the door to her himself. At this, he said I was vengeful.
He spent so much time arguing with me and trying to get the last word in the conversation - with my mom telling him to stop because I needed to get ready to leave - and he only left here at 12:50 pm! Isn't this ridiculous? He left when the lady was here already, for sure! Then I cried so much afterward. But I was also a bit mean as I got late on purpose to open the door (which led me to my mom calling me, too). And now I have to go there and close it.
I don't know what to do, tbh. To be honest, I happened not making plans, so it's true I lied (and probably had no big reason to get upset at this...) but I had some work to do in the morning which got completely interrupted because of that favor. And now I need to get back to it but I can't, I am a mess!
I don't know why this bothered me so much - my take is that it messed with my routine and expectations and that they're too intense and stressed whenever they're late, making a big deal of everything and ruining my peaceful mornings -, and I hate how I feel I was being too complicated and threw that comment. But at the same time, he was the one who felt attacked and got into an argument, right?
They don't like to be indebted and I'm pretty sure he knew it was on him - if he needed to get to the party early and couldn't afford to open the door to that person, why wouldn't he just organized himself better? Every time we plan stuff and he says he's in a hurry, he still makes no effort to get up earlier, leaving the house later and then throwing shit because he's late!
But it's ridiculous the religious talk and the way he was trying to manipulate me into thinking I was calling him names, etc. And the whole "do a sacrifice for all the poor infants of this world". For God's sake!
Now I have to go and close the office for them, haven't had lunch yet, nor do I want to. I need to work, but I also need to go shopping for something and have no interest or willingness to have dinner with them.
submitted by Scapegoat24 to narcissisticparents [link] [comments]


2024.05.18 15:32 Gambit-Accepted DAK Battlegroups And DLC Ideas

DAK Battlegroups And DLC Ideas
With the recent additional content for DAK, I’ve had a lot of ideas poking around in the back of my head about new battlegroups that could be developed and other related ideas for DAK. Having a creative bent of mind, I decided to do a write up of these ideas for publication, ideally to influence what comes out later, but mostly for my own enjoyment. This is what this post contains.
The perspective I’m coming from in this post is that, to me, it would be non-sensical for Relic to develop another sequel to Coh, as the release of Coh3 has demonstrated that you have to compete directly with the predecessors, leading to schisms in the playerbase. Moving to Coh3 made a lot of sense, as the technology required updating, but now that that is done, I feel doubling down on DLC for Coh3 in terms of new factions, battlegroups and content is the way to go, unless some fundamental technology leap happens in the next 10 years. Coh3 should be treated as the ‘platform’ on which Coh is developed. Even if we have to wait another 5 years for another faction, this probably makes the most sense. This way, the effort that would go to porting functionality to a new game, can be spent on creating new content and new features for the already existing game.
In terms of the design of the battlegroups, I wanted to make them thematic, different from existing battlegroups, unique and mostly historically accurate. The interesting aspect of DAK battlegroups is that you have a limited pool of units to work with.
Without further ado, here are my battlegroup ideas:
https://preview.redd.it/ln47ig1ct61d1.png?width=1308&format=png&auto=webp&s=931bc2205f9585526dc0543c3b24fb7f15611ccc
Central Idea: Logistics, augmenting Halftrack Deployment System. The battlegroup focuses on mobility and efficient resource expenditure.
Opel Blitz Fuel Truck: The Opel Blitz Fuel Truck should have two effects with the lockdown, when locked down on fuel, it should increase the rate of fuel supply, probably by more than a normal cache, however when locked down in base, it should reduce fuel cost of the vehicles in the selected structure, so kind of like officer supervision. This would encourage more active micro management of the unit. When it dies it should have a large AOE explosion, meaning friendly units should avoid it and also that it can be driven towards enemy units, kinda like a less efficient Goliath that you can't manually detonate, I can’t see this being anything but ludicrously fun. You really could go nuts with the audio design on that. Top Up Vehicle should be an ability that can be targeted on friendly vehicles. Once done, the target vehicle has faster speed, acceleration and deceleration for a fixed distance. Note this is a fixed distance, instead of time, so if the vehicle doesn't move, it won't 'expend' the ability.
Recharge Halftrack Deployment: This feeds into DAK’s tempo playstyle by allowing you to muster units rapidly. The situations where I see this being useful are early in the game when you want to get double call ins early to build out your composition at a discount or later in the game where you’re trying to mass late game armour quickly. For instance, calling in a P4 as a stopgap measure before calling in a Tiger 90 seconds later, especially if you build up a bank in the lategame.
Panzer III Munitions Supply Vehicle: Largely self explanatory, its like the Munitions Store for US, except mobile and provides different buffs. I could see this unit being coupled with ATGs and LeIGs being strong, as well as recharging snares faster, it compliments that infantry and support weapon playstyle nicely. The unit also can drop MG42s and Mortars, which give DAK manpower efficient access to more team weapons, diversifying potential builds.
Vehicle ROF Ability: Self explanatory. Could see it being strong on Marders, Tigers and Stug Ds. You could make this a global ability but here I’ve stuck with a unit ability.
Ability/Upgrades Discount: This essentially makes Unit Upgrades and Unit Abilities 50% cheaper for the duration. Its thematically appropriate and potentially a strong ability. If you could pair this with the Panzer III Muntions Vehicle, grenades would be cheaper but also recharge faster, although this combination could apply to a whole bunch of different things. Strategies where you rush this ability to ‘mass upgrade’ MG34s on the PGs could be a thing, although you’d need a fair bit of munitions banked up. One thing that could be experimented with is applying this to mines, where you could pop this to spam out mines, depending on how expensive the ability is, the calculus might add up.
Panzer I Command Tank: Feeding into that tempo style again, this early game vehicle would have roughly the potency against infantry as a 250, albeit with better armour. However, the main appeals are the capping and mobility bonuses, these would allow you to rapidly gain map control and would give you an edge when switching sides of the map. For flanking manoeuvres, this would also come in handy, one combination that would be strong would be your vehicles ‘Topped Up’ with the mobility bonuses from the Opel Blitz Fuel Truck and your infantry buffed by the Pzr I Command Tank, meaning your forces can get off flanks or respond to threats much faster.
Withdraw & Refit: Again interacting with the Halftrack Deployment System, this allows you to trade in vehicles that are not needed for resources, exactly like with Brits. I could see this being useful when you want to get rid of 250s that you have spare.
Panzer III S-Mine Launchers: This would be an ability on the Panzer III that allows it to launch S-Mines. I could see this being implemented in 2 ways, either exactly like the Tiger S-Mine launcher ability, which would be really strong for flanking AT Guns or chasing down squads, or if that’s too strong, more like the grenade ability on the Sturmtiger in Coh2. Again, this synergises with the Panzer III Munitions Vehicle and the Ability/Upgrades Discount ability.
Panzer III Side Skirts: Self explanatory, improves the armour and health of your Panzer IIIs after a unit upgrade is purchased. I wouldn’t be in favour of this being an instant upgrade to all units. This would again synergise with the Ability/Upgrades Discount ability.
Lorraine Schlepper Mobile Artillery: Finally, mobile artillery, not unlike the Wespe, giving DAK another tool in the box at their disposal.
https://preview.redd.it/japhac3bt61d1.png?width=1496&format=png&auto=webp&s=3e701d51062abcefb4181342300ec17de4d2fcf1
Central Idea: Fire, anti-cover. It would be strong against team weapon camp gameplay.
Incendiary Grenade Assault: Its essentially the exact same as the Assault Gren grenade assault, except Panzer Grens have access to it and its better at denying cover. So I see this being useful when you want to dislodge infantry in cover or make a Team Weapon move, as they won’t be able to jump back into cover or move back.
Detonating Shot: This ability is available for; Paks, Marders, P3s, Tigers, P4s, Stugs, Flak 36s. While active, if you land a kill shot on a vehicle, that vehicle will blow up causing AOE damage to nearby units. How good this should be will need to be tested. The basic counter play would be just to split up your units, but that requires micro. On the flip side, using the ability well also requires micro and good timing, so there’s a skill factor involved. This ability can also be used on ATGs and Indirect fire units (including emplacements), and if you land the kill shot on these units while the ability is active, it not only explodes but also, importantly, destroys the weapon outright. So you wouldn’t need to focus the decrewed weapon afterwards. This is pretty strong against team weapon play.
Indirect Incendiary Rounds: Exactly like it was in Coh2 for the same units. It also applies to the 254 Artillery observer. All of these barrages are good for area denial and also killing off emplacements.
21cm Nebelwerfer 42: A heavier version of the Nebelwerfer, relative to Wehr’s one. This would have higher alpha damage on it’s shells and the flame dot damage to boot. Only 5 rockets though.
Incendiary Creeping Barrage: Self-explanatory, area denial tool, good against team weapons and emplacements. Strong for denying VPs.
Double Flamethrower Panzer Pios: Strong upgrade naturally, but expensive. In order to get the double flamethrowers you need to buy each flamethrower for 50 munitions. It makes the squad a massive target.
Flammpanzer I Assault Group: This is very much a shock callin, you’d get this to drive your opponent off the map in the early stages of the game. Relative to the L6/40 with the flamethrower upgrade, this would be more potent as it retains the coaxial MG. Relative to the Flammpanzer III, it would have less health but come earlier. Combined with the Panzer Pios, it’s a strong power spike which would be especially good on urban maps.
Inspired Assault: Exactly like it was in Coh1, it was an interesting ability.
Sd. Kfz. 233 Armoured Car: In the great pantheon of DAK light vehicles, where does the 233 fit? It would be most comparable to the Stummel and the Scott, being effective against Team Weapons and Camp playstyle. Unlike the Stummel, it would be more effective at short range, as it retains an MG42 and has the canister round, as well as having more health. Relative to the 8 Rad, it would be worse at chasing infantry on retreat (although you already have the Flammpanzer I), but it would be far more proficient against units at range, units in cover and team weapons. Relative to the StuG D, it would be faster, cheaper and require less teching, but would have worse armour.
Heavy Incendiary Bomb Drop: Extremely good against team weapon camp, emplacements and units capping VPs. Could potentially neutralise points like the Dive Bomb in Coh2?
https://preview.redd.it/aipq57z9t61d1.png?width=1020&format=png&auto=webp&s=0bba7347d9d2321fca701d0e1b97fac68f4d1a0f
Central Idea: Heavy Team weapon play, this battlegroup is the only one that ‘goes against the grain’ of the DAK traditional playstyle by offering you more of a camp based strategy.
250 Reinforce: Essentially a utility ability that congeals with the rest of the battlegroup. Although I could see it being useful in combination with Assault Grens as well.
Pak 36 ATG: Light ATG, effective against Light Vehicles. Unlike the Pak 38, it requires no tech, so you can get it early and allows you to tech T2 while still having ATG support. The Stielgranate 41 shot improves it’s penetration against vehicles, although at the cost of munitions.
Tobruk Bunkers: Variety of emplacements, lots of photos of the DAK using these in WW2, hence the origin of their name. For defence in depth, these are going to be strong, you could have one of the Panzerturms in the back to prevent light vehicles or infantry from breaking in. The 360 Bunker is not fundamentally different from the Wehr AA piece, however, to make it more skilful, it would be cool if you have to manually switch the firing arc.
Flak 37 AA: A larger and more powerful AA than the Wehr Flak 30. This would be more effective against light vehicles and infantry, although could be made slower to move around, and have slower pack up and setup times, to balance it. My thinking is something like the speed of Pak 40s in camo would be slow enough to make indirect highly effective against them. It would encourage using them in conjunction with a tow vehicle, moving them around the battlefield quickly would be impossible without a tow vehicle, although not strictly necessary.
Rapid Suppression Barrage: This is mostly a standard off-map, except that the shells also cause suppression. My thinking with this is that it should cover a broad area, with a relatively short delay between each shell, with each shell having a large AOE suppression. Perhaps the effect would be best compared to the Nebelwerfer from Coh1, minus the flame. What you essentially use it for is area denial and forcing off squads.
MG131 HMG Team: Essentially a ‘premium’ HMG team, the same way the MG42 and DSKH were considered premium in Coh2. Its suppression and damage would be far better than the MG34. It should perform relatively well against light vehicles, like the .50 Cal did in Coh2. The HE rounds ability I see performing better against units in cover, potentially even allowing you to perform cover suppression.
Sd. Ah. 52 Supply Trailer: The Supply Trailer requires some explanation. My thinking with this is that its a brand new unit type, which loosely can be defined as a support weapon. How it works is that infantry squads can crew it, push it around, vehicles can tow it, etc. When in a position, it provides an aura which in this case gives nearby units additional construction options as well as increasing pio construction speeds and giving vehicles the ability to hull down. However, the unit shouldn't require pop cap and moreover, you can actually manually decrew it and it will still provide you the benefits. So for example, let's say it spawns in your base and you want to setup a strong point, you can crew it with a squad, wheel it over to a house near the frontline and then decrew it. Units within its vicinity would still be benefiting from the aura. When you want to move it, recrew it again, or tow it, to a new location. The beauty of this dynamic is that your opponents can steal these units from you like an ATG, so while they don't take up popcap and would be relatively cheap (say 100 to 150 manpower), you're still incentivised to protect them. You can also attack move them with AT guns etc, would be interesting to play around it. I think it would make for an fun dynamic, but would need to be coded from scratch. It also indirectly makes tow yet more useful. With this trailer specifically, it’s aura will make the area around it a point where you can dig in. Multiple squads would be setting up sandbags, vehicles would be able to hulldown and it can also distribute medical supplies.
Off-map Mortar Creeping Barrage: Fairly straight forward light off-map.
Hold The Line: This allows you to hold onto territory easier. A global ability, while in capture circles, your infantry will be hardier. Moreover, they can also reverse the capping progress of your opponent when you contest the capture with your own unit, although you can’t use this to capture territory that is contested. This will be really powerful in VP wars.
15 cm sIG 33 Heavy Infantry Support Gun: The star of the battlegroup. This would be like an LeIG but dialled up to 11. It would have 110 range direct autofire (so like Free Fire Drills), but with a slower ROF. The team would be able to move it around without tow, but like the Flak 37, it would be incredibly slow, like a Pak 40 in camo. The demolition shot would have a much shorter range, like 50, but be incredible against emplacements, although if you manage to get vehicles or team weapons it would be deadly as well. The trick shot nature of this should make it easier to avoid. So kind of like a Sturmtiger but much easier to notice and dodge, while also being less powerful. Realistically you would need to use tow to get it around, but its not strictly required.
https://preview.redd.it/4yg3itn8t61d1.png?width=1012&format=png&auto=webp&s=bb6f1e7b2a4c8d145cfe231db303b0474c33d4e9
Central Idea: Vision, having awareness of the battlefield and executing flanks. Conceptually this battlegroup is the opposite of Battlefield Espionage.
Horch 108 Recon: A heavy ‘ultra light’, which sounds like an oxymoron, but to put this on a scale, it would be better than the Krad as a harassment tool, but not as good as the 250. However, the 250 can’t cap and this can, whereas the Krad is cheaper, faster and has more vision while stationary. So there are trade offs to all 3. The Flak 38 gives the Horch better scaling than the krad. Relative to the Dingo, the Dingo should win, but one would expect the fight with the US Jeep to be more even, if not slightly Horch favoured.
Forward Observation Posts: These are equivalent to the battlefield espionage beacons, except they’re focused on providing LOS. You set them up with infantry and they can be faced to an area to provide sight. I could see these being super handy on the edge of the map, overlooking a flanking route.
Sd. Kfz. 263 Panzerfunkwagen: The Panzerfunkwagen would be a solid sight tool. The MG would be roughly as good as a 250, so you might want to use it aggressively early on, but you’d mostly be using it as a mobile sight platform. With cautious movement, you would be able to spot your opponents forces from camo and the Mark infantry ability should have a short cooldown and be free. You’d mark several units and they would make they more vulnerable to small arms. This would reward active micro management.
Timed Infantry Sight: Amazing for executing flanks, you can detect enemy units before they see you. This should make getting around MGs and picking your engagements far easier.
Panzer Commander Upgrade: Exactly like Coh2.
Suppressive Fire: Gives various units access to a suppressive fire ability. Coupled with the sight abilities, you can trigger this before an opponent’s unit comes into range.
Sd.Kfz.6/3 AT Halftrack: Weaker than the Marder in terms of health, the ATHT has the benefit of providing mobile AT without needing to tech T2. The ranged shot works well in conjunction with the sight tools allowing you to get off shots against more powerful vehicles without taking shots in return.
Temporary 222 Recon Group: Double 222s arrive off-map, they are in your control and you can use them how you please. However, after 75 seconds, they turn to AI control and leave the battlefield. By the time they reach the front, you’ll have roughly 60 seconds to ‘go nuts’ and do as much damage as possible. They don’t require manpower, fuel or popcap. This feeds into DAK’s tempo, all-in playstyle. So I could see a player building an 8-Rad and then using this ability, using the sight tools to determine where the ATGs are and then going all in, the 222s are relatively expendable. The 222s should benefit from the armoury upgrades, so in the lategame you could use this ability to jam captures or sneak off to grab a VP. As an opposing player, mines, hand held AT and snares are your friends. 222s should basically require 1 snare to cause engine damage. Some people have said they don't like temporary units, I haven't seen a good argument against them yet.
Bf 110 Autocannon Heavy Strafing Run: A heavy anti infantry strafing run, akin to the IL-2 strafe in Coh2. It would also be of variable length. Let's say X is your first click and Y is your second, which marks the end and direction of the run, the default run is diagram A, but you can drag the cursor of point Y as far as you want, with a maximum of either 35 range or when you don't have enough munitions banked up for the run. This gives you the flexibility of deciding how much you want to spend and where it will land. A well placed strafe on retreat could be devastating. The cursor should highlight the munitions cost as you drag from point x to point y.
Me 210 Light (SC50) Bombing Run: This is a much lighter bombing run than the US carpet bombing. It should be single line and relatively fast, the damage of the shells should be roughly equivalent to 5.5 inch artillery shells.
https://preview.redd.it/qi30nfn7t61d1.png?width=1417&format=png&auto=webp&s=200547a5ba6b66003c79100161f2613bc96b8c4f
Central Idea: Map presence, retaining position. The battlegroup was inspired by the invasion of Crete.
Luftwaffe Ground Forces: Somewhat similar to the Coh1 equivalent, they would be a fairly weak combat squad with lots of utility. In this case, they would have various construction options as well as being able to heal squads. L.P.Z. Light AT Mines would be more spamable than your standard mines, would be cheaper and only detonate on vehicles. If the vehicle is on less than 80% health, it would cause an engine crit. As an alpha damage, probably 75% of the standard mine would be sufficient. It would require 2 of these mines to detonate on a full health vehicle to engine crit it basically. Dosenmines are essentially like S-Mines and would be planted in patches. The M30 Drilling Shotgun Shot ability would be targeted on a squad and would have short range of about 5. You’d more or less use it like you would a grenade, except it like a throwing knife and the Sniper Shot ability, it can’t be dodged. More than likely, you’d get just one of these squads to augment your composition, with PGs as the mainline.
DFS 230 Glider HQ: Essentially a standard glider, you can drop it in to provide in field reinforcement. However, this glider can also heal nearby squads and recrew team weapons. In addition, the DFS 230 has roof top MG15 upgrade, which turns it into something akin to a light MG emplacement. So there are a few ways I see this being useful. One would be to drop the glider so that it covers your cut off, upgrade the MG and it will make it much harder for your opponent to cut you off and you’ll get infield reinforcement with healing. Maps like Famonville and Road to Tunis, this would be immensely useful. Another use would be in intense VP wars, at the end of the game you want to secure a flank VP, you drop the glider in and upgrade the MG, in many ways its like an auto build, quick deploy MG emplacement, that can also reinforce. Great for map control.
250 W/ Flak 38: Fairly vanilla, like the other 250 callins except with a Flak 38. The Flak 38 would have identical performance to the Flak 30 of Wehr, one way to differentiate them would be to give the gun shield heavy cover properties, but reduce the unit to 4 men to compensate.
Ju-87 Multi Vector MG Strafes: Essentially 3 separate strafes that you call in one after the other. The difference between this and a standard MG strafe is that these strafes give you what is essentially a ‘bulk buy discount’, but also, since they can be targeted in 3 totally separate places within LOS, your opponent has to react quickly to dodge all 3 of them. Its acts as a micro spike test, where you quickly throw them down and they quickly have to dodge. The skill of placing them all fast and accurately needs to be matched by the skill in dodging them all. Moreover, when combined with an attack with units, it can create an overwhelming set of threats.
Bomb Drop Overwatch: The most comparable ability to this would be sector artillery. However, in this case, its planes dropping bombs on units that come into the territory. Its not exactly a loiter though as the planes wait off map, they can still be shot down however. In terms of how strong the bombs should be, it would require testing but somewhere between a 5.5 inch shell and the US Dive Bomb would be a good place to start. Ideally a broad AOE, with only a small zone of full damage. This tool would essentially be used for area denial and be really strong in VP wars.
Ready Reinforcements: A fairly straight forward ability that speeds up reinforcement and allows quick return to the battlefield, again allowing you to retain field presence. Another feature of this ability is that it speeds up in field reinforcement and allows infantry to sprint in friendly territory outside of combat, being able to react to hot spots faster.
Junkers Ju 52 Reinforcement Pass: This is most comparable to the Paradrop Reinforcements of US, except where that ability is a stream of reinforcements over a long duration, this ability is more geared towards a burst of reinforcements all at once. There’s an element of skill in its deployment, as you’re incentivised to line up as many squads lengthwise as possible to maximise reinforcements dropped per munitions expenditure. Since its substantially longer than wide, you could have several squads in different engagements all ‘caught’ in the line and all benefiting from the ability. I could see this happening when you have multiple squads spread across the centre of the map and all located within the area of effect. The ability can be used to swing engagements and keep units in the field.
Paradrop 4.2cm Pak 41 Team: Self-explanatory, the performance of the Pak would be better than both the Pak 36 and the 38, as well as being more mobile than the 38. Useful to quickly deploy AT to a trouble spot.
Temporary Bolster: During the duration of the ability, squads can get an extra man. So Panzer grenadiers can go from 5 to 6 (or from 6 to 7), MG34s go from 4 to 5, Paks likewise etc. This applies to all infantry and support weapons. Once the ability ends, the extra model doesn’t leave, but when the squad drops back to normal numbers of models, it won’t return to the bolstered level until the ability is reactivated. What this ability allows you to do is augment the heath and DPS of your squads temporarily, making them more survivable in the field. Obviously though, the extra models are not free, costing both manpower and munitions.
Temporary Fallschirmjägers Assignment: Like the 222 assignment in the previous battlegroup, this involves you taking control of 2 squads which leave the battlefield after a period of time. In this case, 2 squads of MP40 Falls are dropped where you like and then can be used to sow carnage for 75 seconds from when they touch the ground. Their MP40s make them ideal for flanking team weapons, they have smoke grenades and the can throw short range snares. So you could potentially drop them in behind the lines with the intention of catching a vehicle trying to back up from the front line. One massive use of this ability will be in VP wars, where you drop them onto a VP in the lategame to swing the match in your favour. They don’t cost manpower, population or upkeep, but require a lot of munitions.
Historical Accuracy Notes
A few notes on what is inaccurate or anachronistic. The Panzer III Munitions Vehicle, as far as I know, wasn’t used in Africa but on the Eastern Front. There was another, the Lorraine Schlepper Munitions Vehicle, that was used in Africa for the exact same purpose and this could be used instead, but the benefits of the P3 are reduced development cost as some of the voice lines and the vehicle sounds can be reused. I’m also not so sure whether Side Skirts were used on P3s in North Africa, I haven’t seen photo evidence in any case.
The MG131, while used in a ground HMG role, I haven’t seen evidence of it being used by the DAK in North Africa. About ten Sd.Kfz.6/3 AT Halftracks were used, some people might object to that unit on these grounds. I haven’t seen evidence of the Pak 41 being used in North Africa, I’m also fairly sure they didn’t paradrop them. The M30 Drilling Shotgun was used in North Africa…but only by downed pilots. The Madsen Belt Fed MG was a Luftwaffe contract gun, but I haven’t seen evidence of it being used in North Africa. Likewise with the Panzerhandmine 3. Needless to say, all these are exceptions. Otherwise, to the best of my knowledge, these designs are historically congruent.
Design Notes
I deliberately avoided using Italian Units in these designs. Following from what I said about Relic doubling down on Coh3, I feel it makes sense for them to eventually create an Italian Faction, so I didn’t want to cannibalise that faction, especially when the DAK already has plenty of material to play with.
What to do with the remaining units in the files?
There are several other units in the game files that I haven’t used here. This was intentional. Several people having been calling out for the substitute vehicle feature from Coh1:
https://preview.redd.it/ijcq0sb6t61d1.png?width=1280&format=png&auto=webp&s=62585a9618ad9fb793d9ce95dcaccacf61dabaaa
As a feature it makes a lot of sense, I feel the community would be far more interested in small and frequent content drops like these instead of cosmetics and they could be priced to be more profitable than battlegroups at less development cost. They would ideally be more frequent as well, bringing players to the game. I feel games like War Thunder and WOT benefit from the sheer variety of units and I can’t see how this wouldn’t apply to Coh. Whenever they release, the units will be similar enough to the units they replace that they won’t disturb balance much, meaning less emergency balance hotfixes.
I feel this is what makes the most sense for the units already modelled, for example, the Panzer II is fundamentally serving the exact same role as the 8-Rad, they’re both 20mm autocannon light vehicles. Its hard to imagine a build where you would build both of them in the same composition and trying to make them different would be clumsy. We see this with the L6/40s, which are also similar to the 8 Rad and have been specialised to be worse against infantry and better against vehicles, to mixed results. Then there’s the 250/9. Adding another autocannon light vehicle via a battlegroup wouldn’t be that different from what we already have but as a substitute vehicle it makes a lot of sense. This logic can be applied to most of the vehicles already in the game files. The substitutions I would advise would be:
https://preview.redd.it/rermeob5t61d1.png?width=584&format=png&auto=webp&s=9a507899379f8fcd8c50d3ae04d85f8982f7ca12
The Panzerjäger I is already in the game files and could be substituted for the Marder. It would have less health and worse pen, but could be made significantly cheaper. This would be an interesting trade off in the composition. Alternatively, there’s the Marder III H which also could be made as a substitute, it would largely have the same performance but could have an MG upgrade and have a different starting price.
https://preview.redd.it/1jsj20n4t61d1.png?width=698&format=png&auto=webp&s=8be575f13ce97a2cd6c3e773ce16d67885949a5c
The Sturmpanzer II would have a much larger up front damage, closer to a Brummbär, but would have a lot less health and far worse frontal armour. You wouldn’t be tanking Bazooka shots like you do with the StuG D but it would be significantly more deadly.
https://preview.redd.it/gza0pvy3t61d1.png?width=526&format=png&auto=webp&s=c3425632265b68ee6e8d47216ceb8d6c0f36b83b
For the Opel Blitz Flak 38, it would be cool if this worked more like the Flak HT in Coh2, with the set up time and suppression. So this unit could be made cheaper and have the same role as the Flakvierling, but be more finicky to use.
Others:
https://preview.redd.it/mtp4c3a3t61d1.png?width=702&format=png&auto=webp&s=32e312dabe55957321e2ec9af9e8f89f89709906
https://preview.redd.it/n0klnvo2t61d1.png?width=652&format=png&auto=webp&s=e5825bd63a95e22090b3b9f52a8f820e61054537
https://preview.redd.it/59hqrd02t61d1.png?width=617&format=png&auto=webp&s=428ac413c7d8617936417072a1e74e0116285c46
https://preview.redd.it/9xmco9e1t61d1.png?width=813&format=png&auto=webp&s=3f34a21b37f36313900d7dc0cc2f0fa025370b03
Conclusion
This is what I would do with the remaining DAK content, short of a rework. The battlegroups are unique, fairly historically accurate, thematic and interesting. The concepts can at least be stolen and repurposed elsewhere. If there’s anything clearly broken or so amazing that it needs a shout out, feel free to let me know. I have other ideas for the other factions but I'm still pondering them.
PS. This is a repost from before, when I initially posted this I didn't understand how Reddit worked.
submitted by Gambit-Accepted to CompanyOfHeroes [link] [comments]


2024.05.18 15:20 SuccessfulComfort290 Microphone doesn’t work with Emulator on IPhone

I’ve downloaded several old ds Game Roms and I have been playing them through an emulator on my iPhone but I have two significant problems.
First Problem my Game Sounds keeps bugging. Sometimes the sounds is fine and then it suddenly changes. The games work like normal but the music sounds like it’s really buggy, this doesn’t change even when I have a good internet connection.
Second problem and this is really important: Some games require me speaking into the microphone or blowing in the microphone but this doesn’t work no matter how loud I speak or if I wear Headphones. I’m wondering if this is a bug or its just how it is since these games were made for the Nintendo Ds and not the iPhone but why would there be the rom that works on the emulator if I can’t properly play the game…
I really hope someone has some answered and can help me out :3
submitted by SuccessfulComfort290 to emulators [link] [comments]


2024.05.18 14:52 EggplantRough6633 Ranking All Classes I've taken Too!((MonkeyPOV))

Well, praying that I didn't fail my last two classes💀 I’m finally done with my degree. So why not share my unfiltered opinion/experience that I’m sure Faculty has been eagerly waiting for? Ranking wrt:
Course Content / Instructor / Organization / Exam/Pset Difficulty. Copying most recent post's format. Major congrats and shoutout to all graduating this semester and beyond, it's been more than real.
A lil motivation: don't give up, don't ever give up...
live look at brain having bruh moment during exam (is this a record?)
S-TIER:
  1. CS 1110 - Intro CS Python: Will always be goated course for me. After switching majors, was very intimidated by CS. Prof Lee/Bracy & staff were godsent, course was very enjoyable and beginner friendly (duh) while remaining very fulfilling and challenging. Projects/Labs were very helpful and plenty of resources for help, enjoyed studying for exams and material thoroughly. Thank god I did not stick w Matlab (unbiassed opinion why do you ask)
  2. ORIE 3500 - Prob & Stats II: An out of whack sequenced class took during summer but love how Goldberg teaches. Not sure if still applicable but grading was very friendly and not a lot of tedious course work but learned a lot and enjoyed class. Exams were challenging but fun and grade cutoff made learning pressure-free. Shoutout D Goldberg one of my favorite professors
  3. ORIE 4580 - Simulation Modeling: Took this course w/o prereqs so was unprepared but Henderson is amazing person & Professor and will help you out. Really enjoyed Simio and project/assignments were fun, interactive, interesting. Shoutout Henderson: great guy award helped me through rough spot super approachable/easy to talk to. Decent amount of work and I didn't understand half of it but tools and info still relevant
A-TIER:
B-TIEUSEFUL:
MIDDLE-UPPER-LOWER-TIEGEED:
EASY/CREDIT:
BUNS:
  1. MATH 1910 - Calc I: Did shitty after prelim 1, not bad course but possibly recommend taking CASE exam if you already know material, kind of waste
  2. ENGRD 2110 - Obj-Oriented Prog: Took in summer, was hopeful after enjoying CS1110 but class and content not as fun. Liked VanHattum, call me?
  3. PHYS 2213 - EM: Imma be 100p here and not even pretend I deserve credit hours for this course but was available online (ilovecovid) so that was no brainer. Least favorite stem class. Dont cae
  4. PSYCH 2350: Don't remember taking this. typical canvas credit course
FEVER DREAM / C&B TORTURE:
  1. ORIE 3510 - Stoch Proc I: Second class I failed 😎 Somehow made less sense 2nd time. Cursed course its hard to recognize when you are fully wrong/using wrong intuition but you might not realize this until you get a 31 on the Final. Must attend in person. Thought it would cake retaking but had Scully who is great guy/genius but taught it almost entirely different format than previous year. Info seemed to go in one ear (wp= u/λ) and out the other, not a fan of his notes/material organization. Scully is huge improvement from Dai nonetheless.
  2. MATH 2930 (First time😉)- DiffEq: My first failure!🤓 (took it when it was hard i swear) Even though 1st time through was rough, enjoyed solving equations and remains my central to major, def most involved of required math courses. Restructured version was an actual joke compared to previous year, legit had the option to retry & submit everything you turned in until you essentially got it right via brute-force submitting every possible answer.
  3. FWS: (Challenges of Modernity): Sigh
  4. ENGRI 1160 - Modern Structures: cool project but prof was hard to understand and psets were way too hard for sem1 intro eng course. TA could barely help, made me switch out of civil
  5. FWS(Anthrop Persp. of Tech Worlds)?: Now they invent ChatGPT, sick
O-H
  1. BIOG 1250 - Biology Seminar (The Rise and Fall of Viruses): Went to class for 3 weeks and learned ab Kentucky bluegrass and rocks, realized class wouldn't count towards major so dropped but figured I'd throw it in here.
submitted by EggplantRough6633 to Cornell [link] [comments]


2024.05.18 14:35 b3nchT3chSt3r1ing Best men's multi picks? Thoughts/input on overall approach.

Pick's for Men's Vitality Multi? Thoughts or Advice on Overall Stack/Approach?
Picks for men's vitality multi? And thoughts on overall stack/approach?
I have been a vitamin person for probably a good decade now (unlike many of my peers which blows my mind) but I can attribute them and routine exercise to greatly improving my health and how I view myself. I think I've hit my stride in terms of my overall wellbeing and professional performance in relation to my supplement routine over the last year or so. I am in a stressful line of work that's demanding mentally and people management-wise and requires deep focus, creative thinking, poise and charisma. I myself am predisposed to depression and coupled with my job can impact my libido. TLDR here - basically I want to keep fit while optimizing my mood, focus, cognition and sex drive.
I have been taking GNC's performance and vitality (GNCPV) packs on and off for awhile now and can notice a difference in my athletic energy and libido. https://www.gnc.com/vitapak-programs/219812.html?ogmap=SHP%7CNBR%7CGOOG%7CSTND%7Cm%7CSITEWIDE%7CCATCHALL%7C%7Bcampaign_name%7D%7C%7Badgroup%7D%7C%7C9279358699%7C93587336549&gad_source=1&gclid=EAIaIQobChMIg7D8weGQhgMVpTbUAR0rpQN2EAQYASABEgINmvD_BwE&gclsrc=aw.ds
I like the combo for the cost and convenience, but wondering if there's a better holistic option out there.
For added context or input, I take daily digestive enzymes with pre and probiotics. I also subscribe to Athletic Greens which I'll alternate with the GNCPV as my daily multi through a given week. Some days I'll take both if I'm especially active or eating more. For brain and stress, I'll add in a stress complex called Anxiety-T with l-theanine, kava kava, GABA, etc., an omega 3 fish oil, and a mushroom complex that has the notable shrooms, heaviest in lion's mane, with ashwaganda, bacopa, ginseng and others. I def notice I'm calmer and less nervous for things with the Anxie-T but wondering if I could be doing something else to check these boxes better.
submitted by b3nchT3chSt3r1ing to Supplements [link] [comments]


2024.05.18 12:35 Practical-Half3526 Gaming table solution

I was looking at toppers and other table ideas for something that could be put away when not in use. I found something that worked pretty well at Lowes and wanted to share. 3 2x4 cosco tables (50 each) https://www.lowes.com/pd/Cosco-24-in-x-48-in-Rectangle-Resin-Gray-Folding-Table/1000640653 1 pack of floating wood flooring to click in place on top (not sure if this is the exact one, but something like it) https://www.lowes.com/pd/Style-Selections-Florian-Oak-7-mm-T-x-8-in-W-x-48-in-L-Wood-Plank-Laminate-Flooring-23-91-sq-ft/1000766734?cm_mmc=shp-_-c-_-prd-_-flr-_-ggl-_-CRP_SHP_PLA_FLR_Online_A-B-_-1000766734-_-online-_-0-_-0&gad_source=1&gclid=CjwKCAjwo6GyBhBwEiwAzQTmc6Cayr-_LKXIJeZ8kz1M0o4N6h7z1v0DpWVFiIQet2fvTimlINZg8xoCyu4QAvD_BwE&gclsrc=aw.ds
what I love about this is how little space it all takes up and I can set up the tables in 4x4 or 4x6 configurations depending on the game (from Wasteland warfare, necromunda, Warhammer) I will probably use bungie cords to attach the tables together when set up.
submitted by Practical-Half3526 to wastelandwarfare [link] [comments]


2024.05.18 10:24 whoisgrayson I think I ruined my fiskars amplify scissors….. help

Hey guys, so I think I ruined my fiskars amplify scissors.
These ones
I have had them for years now and they were starting to get a bit dull and tight to open and close so I removed the blades and sharpened them with this
I put the scissors through all 3 of them.
I put the scissors back together and they felt better and didn’t feel tight when opening and closing them.
The scissors work fine while cutting card and paper but when I attempt to cut through anything soft or plasticy like bubblewrap or tape it doesn’t cut.
Did I ruin the scissors?
Anyone know what the problem might be and how to fix it?
Any advice is much appreciated. Cheers
submitted by whoisgrayson to cardmaking [link] [comments]


http://activeproperty.pl/