Interaction between amoxicillin and bactrim

I'm on amoxicillin every 8 hours for a toothache and the only other medication I take is Aubra EQ (combination pill). I missed my pill yesterday, so I'm doubling up today. I just took my amoxicillin around 9:30am. I was thinking of waiting two hours before I popped both. I'll be fine right? I haven't had unprotected sex in over a week but I might tonight (LOL) so just wanted to make sure. I keep reading there are no interactions between the two but just wanna make sure if anyone else here has had a similar experience.
I started the amoxicillin yesterday in the evening so today will be my first full round of taking it three times a day. The only side effect its given me so far is gas and going #2.

25F, 170 lbs, prescribed vyvanse and adderall daily for adhd and gapapentin very rarely as needed for sleep, decently healthy on paper but my immune system is not the strongest and I’ve gotten a handful of strep and staph infections over the past few years. Had a recent skin infection/abscess on my butt. Went to doctor when it was hot to the touch through my pants, I was sleeping like crazy and I started developing a low-grade (100.3F) fever. It was swabbed, eventually drained and I’ve been on Bactrim since I first was seen for it.
The swab test results just say Staph, which of course I know is what MRSA is, but wouldn’t the results list MRSA specifically considering how serious it is these days? Or are the gram strain results what specify that it is specifically MRSA? If anyone is able to translate/confirm the test results for me it would be greatly appreciated, screenshot is in link below.
https://ibb.co/kMPB7cF
If it is MRSA, is it still able to spread on my body while i’m on the Bactrim? I cleaned/disinfected a lot in my living spaces, keep the wound covered with bandage and mupurocin except while showering, use hibiclens whenever I shower and had the antibiotics extended an extra 5 days because I thought something new was developing on my ear so I’m still on them now. The initial wound is healing up, but I can’t figure out how to know if something new is cropping up every time I see any bump or pimple now. Plus, my lymph nodes keep intermittently swelling, and i’m still running between a 99-100.3 temperature. Is this just a normal response to the body fighting the infection? It’s been probably 8 days of the antibiotics now, I did miss one dose of it last night after falling asleep early by accident but have been consistent otherwise. However, I also was drinking alcohol for the first few days of the Bactrim which I ceased immediately once a nurse friend warned me of the serious interactions and because I was feeling like sh*t when I drank on it anyways, so I’m hoping that didn’t do anything really bad to my body or weaken the antibiotics. I am super scared and have gotten limited info from the doctors and google so any info is really useful.

I believe I recently just experienced bipolar disorder after taking Clarithromycin and Amoxicillin to treat my HP infection in my stomach. I only took them for 3.5 days and had to stop it because the situation went too bad.
At first I felt really good, but started from the third day I started to feel irritated, obsessive about the same thoughts, did some impulsive shopping and forgot them afterwards, feel no tiredness, and started to cry a lot for no reason from time to time. I had difficulty with falling asleep and kept having terrible dreams. I could feel the circle of swinging moods became shorter and shorter.
There was one night I was woken up by the noise of my arteries hitting my pillow (it’s a pillow filled with little plastic straws). At that moment, I was scared and started thinking of going to Emergency Room.
At first I was thinking of taking half tablet of Xanax to ease my pain and restless feelings, which was prescribed by a psychiatrist for my anxiety disorder before(I am still taking 12.5 mg quetiapine every night to help sleeping). But when I started to check the interaction between drugs, I found Xanax and Clarithromycin together may worse the situation. So I started to search the side effects of Clarithromycin, that’s how I found the term “antibiomania”. Until then I just realised that the timeline of bipolar episode overlapped with the medication of antibiotics.
I went to the ER directly after I found this. They labelled me as urgent. But after I told them my story, it seemed that they didn’t know if it was real? They suggested I could quit the antibiotics if they did make me feel uncomfortable, and prescribed some hypnotic and discharged me.
The next several days I finally started to feel really tired as if I hadn’t slept for 4 days. And I was recovered after a week.
The thing is, after that I had follow-up consultation with my psychiatrist and my gastroenterologist. One denied the association between antibiotic and bipolar disorder, the other one said it was the first time she ever heard of this. Frankly, I feel so frustrated and disappointed when I received these feedback, even though I knew it was rare.
But the good thing is I am taking a different antibiotic for HP infection. Hope it works better this time…🤞

Hi there everyone , I’m currently taking buspar twice a day for 5mg , I googled the interactions between buspar and amoxicillin but couldn’t find anything , can I take both at same day?

I wanted to see if anyone else has had bad interactions when using amoxicillin/penicillin while taking qulipta. I’ve found interactions between other antibiotics and qulipta, but it is unclear if amoxicillin is considered one of these. I have been on qlipta since February and it has been great with barely any side effects (little nausea in the beginning). Unfortunately, I got bit by a dog and had to go onto antibiotics to treat it.
The first night I took the antibiotics was awful. I was severely nauseous and uncontrollably vomiting from 6pm to 6 am. Part of my symptoms for migraines is nausea and vomiting so I am very used to it by now, but this was on another level, it just never stopped. I took zofran which didn’t work. On top of the nausea I had racing heart, chest tightness, limbs went numb, and confusion.
The second night was the same but I started to notice blood in my vomit so I went to the emergency room. Just a tear in my osophugus, and got some hydration and they sent me home.
The third day I found this which is the only information I was able to find on any interactions. But the symptoms mentioned match my own.
So I didn’t take the qulipta the third night and I made it through the night without vomiting and extreme nausea. I plan to reach out to my neurologist and let her know as well.
Is this something anyone else has experienced?

I’m taking Amoxicillin, Clarithryomycin and Omeprazole. I’m also undergoing a medical miscarriage. My doctors didn’t seem to think there were any interactions between the meds (mifepristone and misoprostol), but I’m worried. Has anyone else has gone through this or knows about medication interactions?

Note: I sometimes update my post, so please check regularly! - last updated 5/16/2024
Updates with color coding for visibility (and to point out super important information) can also be found here: https://docs.google.com/document/d/1xJQPANRO8XTi-uvncCeNPNM8x6UBmSsjKxFAO9lMWcM/edit?usp=sharing
Hello! For those who are either taking the Naplex for the first time or need to retake it, please note that this guide is VERY COMPREHENSIVE. You may take whatever information I have and use however works best for you. If you study and follow all the information I bolded below, I am sure you will pass. But feel free to DM me or comment below, if you have any other questions. Hope that this guide helps!
P2 students: If you want to get a head start in your pharmacology and pharmacotherapeutics classes, I suggest getting an OLD copy of RxPrep book and studying the different disease states and associated treatments/drug therapies from there as you are going through class. The lectures in those classes can be overwhelming, so reading through the disease state and associated drug therapies from the RxPrep book prior to your lectures and in conjunction with your class notes will definitely help improve your understanding (and hopefully your grades)! Essentially, treat the old copy of RxPrep as a somewhat simplified summary. Only pay attention to the disease state info, drugs, and med safety (side effects, contraindications, black box warnings, teratogenicity, etc.) info though. Don’t pay attention to the dosing so much as these may have changed. The reason why I recommend using an old copy of RxPrep at this stage is because it is extremely cheap. Save your money for the more expensive and updated version for the end of P3 year!
P3 & P4 students: If you want to take the Naplex as soon as possible or do really well on your APPE rotations, I suggest studying from the most current RxPrep (or whatever resources you want to use) dated for the year that you plan on taking the Naplex during your rotations, starting with the chapters most related to your rotations first (obviously), then on the bigger chapters listed below, then the smaller chapters. This is most critical for those looking to apply for residency or wanting to get licensed ASAP. Otherwise, you may make your study schedule on your own. Please note the type of learning that works best for you. If you are someone who struggles with retaining information, you should start early so you have enough time to review enough times to absorb the material. If you are someone who procrastinates a lot, please plan your study schedule wisely and effectively.
How to get RxPrep at a discount: Close to the end of P3 year, I suggest you get together with a group, either classmates from your school or other pharmacy students on social media, and contact a UWorld Rep. They typically want a list of people who are interested in buying RxPrep at a group discount. They offer different packages, so you will have to discuss that with them, but they should always include the book. Most people also purchase the question bank, which I highly recommend in order to have something to test yourself with, and the majority of the questions give explanations with the answers. There are also the videos, which I personally liked because they do a good job summarizing the information and emphasizing the important info. This is particularly beneficial to those who find the book overwhelming. Just keep in mind that you probably will want to increase the speed of the videos (I did 2x speed), and that some videos may not be 100% updated. If there are any discrepancies, always go with the book info as being correct. But RxPrep does a good job notifying when videos have been updated, if this is something you are interested in.
Study Schedule Timing: Whether you plan on studying early, or are procrastinating, I suggest that you finish studying everything 1-2 prior to your exam, and then use that last 1-2 weeks for overall review and to review weak spots. You don’t want to forget the material you looked over a while ago right before the exam!
Naplex Candidate Performance Report: https://nabp.pharmacy/news/blog/the-science-behind-the-new-naplex-candidate-performance-report/

• Area 1 - Obtain, Interpret, or Assess Data, Medical, or Patient information (18%)
• Area 2 - Identify Drug Characteristics (14%)
• Area 3 - Develop of Manage Treatment Plans (35%)
• Area 4 - Perform Calculations (14%)
• Area 5 - Compound, Dispense, or Administer Drugs, or Manage Delivery Systems (11%)
• Area 6 - Develop or Manage Practice or Medication Use Systems to Ensure Safety and Quality (7%)

Naplex Breakdown on RxPrep by Area:

• Areas 1-3 → Top 300 and all disease state, DDI, OTC, and Tests/Labs chapters
• Area 4 → Calculations, PK, Biostats chapters
• Area 5-6 → Foundations 1 & 2, and Compounding chapters

Studying Recommendations:
Speaking from my experience and skimming through YEARS of study posts for Naplex, I suggest going through the RxPrep book, focusing on the underlined/bolded parts, and then doing all the quizzes until you get at least 70% on each topic. I cannot emphasize how important it is to memorize every "key drugs guy and study tip gal" notes on RxPrep (there are also good quizlets for this). I recommend writing down all the acronyms from key drugs guy/study tip gal before starting the exam. I felt memorizing those really helps eliminate wrong answers on the Naplex enough that I passed despite not being always confident that I knew the answer. Most of the time they give you the lab values and ranges but knowing the “average” value goals for each by heart is a good thing. If there is something wrong with the labs, it should be a very outlandish value, so memorizing the actual range is a waste of mental space. Remember, a value may be slightly off based on the patient’s condition, age, etc. RxPrep does a good job summarizing what labs and tests to look for with the important disease states, so definitely know those (including specific tests, such as pregnancy). Definitely know your foundations 1 & 2 chapters, math, biostatistics, hypertension/cardiovascular diseases, cough/cold/allergy (you will need to know dosing of APAP and IBU for adult vs. pediatric), diabetes, liverenal diseases, infectious disease (main and alternative treatment), major common drug interactions (only the ones in RxPrep chapter for that), immunizations, OTC drugs (only those on RxPrep), side effects for all drugs mentioned in the RxPrep book, GI diseases, respiratory diseases, Chemo man (for oncology), Antidotes, Pharmacogenomics, HIV (know the brand/generic/class names of each drug, MOA/common side effect of each class, and the tests associated with diagnosis/regimen choice).
Now this DOES NOT mean the above topics are the ones that will occur the most in your exam (although it is for most people), because the exam can really ask you about any topic. The topics above are simply the ones that happen to appear in most people's exam and are typically the ones that require more time to study for. Please understand the difference. There is a line between studying a topic well, and over studying for it. You don't want to focus too hard on a few topics and ignore/not study the other topics enough. So, I still recommend that you still review EVERY topic until you get > 70% on the quiz. If you do not reach that threshold, please wait a couple days before taking the quiz again. You do not want to get in the habit of just memorizing the question/answer because the exam WILL NOT ask you the exact same question. It is more important for you to understand what the question is asking, AND why each individual answer choice is correct/incorrect.
ABSOLUTELY MUST KNOW CHAPTERS: Foundations chapters, Calculations/PK/Biostats (obviously), Compounding (mostly the points that I mentioned below), Pharmacogenomics, DDIs, Antidotes, OTC, and key drugs guy/study tip gal. These chapters are the very core as they will allow you to eliminate a lot of answers. This is crucial because there will be questions that you will not know well, and you will need to do your best to eliminate as many answer choices as possible based on those chapters, along with what you know from the disease state chapter. Notice how many of these are all MED SAFETY-related chapters (the biggest purpose of the Naplex to begin with). These are also the chapters that a lot of people might brush over and think they are not important, so they under-utilize them, but from observation, they are the ones that can make a difference between a pass or fail for the majority of people.
For the clinical cases, my biggest suggestion I have for you is to READ THE QUESTION FIRST before reading through the case, and SCAN ENTIRE SCENARIO carefully!! Reading the question first should give you a hint on what you are looking for so that reading the scenario is more effective. You shouldn't have to reread the scenario over and over again, because you should already have an idea of what you are looking for after reading the question itself. Also, there are questions that don't even require you to read the case to answer because the question itself is not scenario specific, so those ones trick people into wasting their time reading the entire scenario for nothing.
When you read the scenario, really read through the questions and all the information, INCLUDING LABS, carefully! The exam doesn't let you move on unless it senses you physically scrolled through everything with your mouse/cursor first anyways, so there is no point freaking out and skipping stuff. The question itself or info/labs/tests should give you some sort of red flag to watch out for. I will reiterate, most of the time the question wants to ask you about identifying safety/side effects and how to minimize/eliminate them (depending on what it is), so keep that in mind! Big things to look for in scenarios are often related to Black box warnings/Contraindications (NEVER SKIP THIS!!), teratogens/pregnancy risk (mostly pay attention if patient is female, but in reality there are some drugs that have this problem in males too), other REMS (know drugs on RxPrep that require that), allergies (NEVER SKIP THIS!!), other side effects, duplicate/antagonistic therapy (Top 300/RxPrep. Make sure to compare home medication list with discharge medication list, and to check if they are getting medications from a different pharmacies).
Here is how you should approach every scenario question:
Step 1: What is the question asking? Is it even related to the scenario (If not, answer the question. DO NOT read the scenario!)?
Step 2: What do I know about the topic the question is asking about? Signs/symptoms? Side effects? Contraindications/Black box warnings? Teratogenicity? REMS? Labs/Tests? → This is basically Top 300 + RxPrep chapter info. If you are struggling with this, you should review that section and redo the quiz on RxPrep.
Step 3: What about the patient case that stands out regarding the topic being asked? Any symptoms/side effects? Duplicate/antagonistic therapy? Labs/Tests? Allergies? Gender? Age? → Once you get Step 2, you should be able to have enough info to look for relevant information for Step 3. With Step 2 and "key drugs guy/study tip gal" you should be able to eliminate a lot, even if you aren't completely confident about the topic.
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Sample Clinical Questions: -- The way I word the questions are oversimplified compared to how they may be presented on the Naplex due to space constraints. I also am not giving you any actual details. This is simply a practice of how you should approach these scenario questions BEFORE you actually read the scenario. For the case questions, you should look at each drug/disease state and ask yourself what kinds of "cases" can they ask of you, kind of like I did in my post. Also, you should definitely go through all the "labs and tests" associated with each disease state, since that is something you definitely need to memorize for the case questions. RxPrep has a great chapter on that. To go about this, think, if a patient was on a certain drug already, or if you tweaked the labs/test results, how would it affect your recommendation? Best way to study for this is to make flashcards/tables of each disease state with the possible treatment options, disease symptoms/drug side effects (including black box warnings/contraindications/teratogenicity/etc.) to look for, and labs/tests associated with the disease state and/or drug (some drugs require certain labs/tests too!).--

1. A patient comes in looking to fill a medication for erectile dysfunction (they will likely just give you the name of the drug). Is it alright to dispense it? (They may give more information such as a list of medications they take from a different pharmacy). → You may notice that the patient normally has medications filled elsewhere and/or you notice that their past medical history mentions angina. It is always a good thing to ask the patient for their entire med list. In this case, if you had noticed any of that, you should look for any nitrates that they may be taking as they are contraindicated with your typical erectile dysfunction drugs.
2. A female patient comes in wanting to get treatment for acne (they may describe the severity here). What would you recommend for this patient? → Notice the patient is FEMALE. You should always look to see if they are pregnant, especially if there are possible treatments that are teratogenic. Also, isotretinoin has REMS, so they may ask about that.
3. A patient presents at the clinic with new onset lower backpain. They describe it as a deep "aching" pain. What would you recommend for this patient? → You may notice that this patient has a history of hyperlipidemia and/or are taking a statin. This may be either new to them, or they may have had a recent dose change. Either way, a deep "aching" pain in the large muscle of the lower back is usually a side effect of statins. A very elevated CK or CPK level would indicate a very strong intolerance to the statin. In this case, either you would lower the dose of the statin or change the statin to something more tolerable (i.e. The less lipid soluble a statin, the less likely it is to have this side effect. For example, atorvastatin is more lipid soluble and more likely to have this side effect than rosuvastatin. But for this reason, rosuvastatin tends to be more "expensive", and sometimes a PA needs to be sent to get a more expensive drug covered by insurance). A lot of the time, they will opt to just lower the statin dose since it is easier and less expensive. However, if the patient needed to increase their statin dose because their lipid levels were still not controlled with the previous lower dose, switching statins may be worth it along with potentially adding a different drug. For example, if you notice their triglyceride level was > 5000 mg/dl, you absolutely need to add a fibrate (fenofibrate is the safest option. Pretty much never choose gemfibrozil since it has a lot of problems, including intolerance) to prevent pancreatitis.
4. A patient presents with myocardial infarction (MI) and was treated at the hospital. The provider asks you what you recommend discharging the patient with. → You may notice that this patient has already taken an ACE inhibitor and Beta blocker prior to being hospitalized to control their blood pressure. Perhaps they have even had an MI previously. You want to make sure that when you discharge, you go through their med list to reconcile it all. If they need to increase the dose or change their regimen, make sure the previous lower dose/medication is discontinued and replaced with the newer dose/medication.
5. A patient comes in with Pneumocystis Pneumonia (PCP). The doctor needs help recommending a treatment for them. → You may notice this patient has an allergy to sulfa- drugs. Generally, the treatment for PCP is Bactrim. Therefore, you need to think of an alternative treatment for this patient. You can find more "practice" online, although it can be hard to find. Here is some that might help:

Click the search bar and type "Interactives: Case Studies" → https://www.pharmacytimes.com/search?pharmacytimes_sanity_data%5Bquery%5D=Interactives%3A%20Case%20Studies https://www.youtube.com/@pharmacyhouse/search?query=clinical%20case%20study
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Overviews/Extra Question Banks:

• TLDR Naplex Overview: https://www.tldrpharmacy.com/content/how-to-study-for-the-naplex
• Naplex Simplified: https://www.rxexamreview.com/index.php
• MemoryPharm (Are you a visual leaner? Then this is for you! This site mixes art and humor to simplify complex pharmacy topics and reviews all there is to know about medications, disease states, and labs. It also provides tons of studying tips, especially memory tips. Also, their store has lots of resources you can buy including Top 200 Drugs Coloring Book, Antibiotics Coloring Book, Mnemonic Workbooks, and more!): https://www.memory-pharm.com/study-topics/
• RxPrep Tables (Note - These are from 2021, so you may need to update information. However, this should give you a good idea on how to approach studying each disease state): https://www.scribd.com/document/493603800/RXPREP-TABLES
• Pyrls practice Naplex: https://www.pyrls.com/naplex
• Pharmacy Prep: https://www.youtube.com/@pharmacyprep1/search?query=naplex
• Naplex Review: https://www.youtube.com/watch?v=hcm56j_Bxmg
• Drug Info (Top 200 and Class reviews), DDI, Narrow Therapeutic Index, Calculations Review and Practice: https://www.youtube.com/@AmandaPharmD/search?query=naplex
• Pharmacy Times → Click the search bar and type "Pharmacy Quiz": https://www.pharmacytimes.com/search?pharmacytimes_sanity_data%5Bquery%5D=pharmacy%20quiz
• Pearson Vue Exam Software Demo → This is a demo of the program that Pearson Vue uses for the exam. I highly encourage you to play around with the buttons to get familiar with the exam software’s functions/capabilities. Due note that I don’t think that “scratch pad” was there when I took the Naplex: https://www.pearsonvue.com/athena/athena.asp

TOP 300 → Remembering Top 200-300 drugs is hard, because it’s…well…a lot. I personally like to associate names with a song/history (like understanding the background or story behind it)/image (like picmonic)/similar words (i.e. hypotonic cells are fat like hippos) that help me remember them better. Here are some links that might help assist with it. Note that they just cover SOME of the most common drugs, but not all the ones you need to know.

• PTCB Top 200 Drugs (Brand/Generic) 100 Question Quiz: https://ptcbtestprep.com/top-200-brand-and-generic-drugs/
• TonyPharmD (Songs to help you remember important drugs by different body systems): https://www.youtube.com/@TonyPharmD/search?query=decoded
• How to Memorize Top 300: https://www.youtube.com/watch?v=1SFqEDNDxHc
• How to Learn Top 200 in 10 Days: https://www.youtube.com/watch?v=jR7d56UeeeU
• How to Learn Top 200 Brand/Generic Drug Names Like a Pro: https://www.youtube.com/watch?v=kuwubVIekD4
• 15 Drug Name Origins: https://www.pharmacytimes.com/view/15-rx-drug-name-origins
• 20 Drug Name Origins That May Surprise You: https://www.pharmacytimes.com/view/20-drug-name-origins-that-may-surprise-you
• Top 20 Drug and Medicine Name Origins: https://pharmafactz.com/21-bizarre-drug-name-origins/

Calculations → You need to score > 90% on both PDF and the calculations question bank on RxPrep. Be aware of how you round, and make sure to time yourself!!:

• Naplex Calculation Problem Practice (PDF): https://forums.studentdoctor.net/attachments/2006-calc-problem-collection-pdf.15108/
• Naplex Required Math Formulas: https://forums.studentdoctor.net/threads/naplex-required-math-formulas.1381455/
• Drug Info (Top 200 and Class reviews), DDI, Narrow Therapeutic Index, Calculations Review and Practice: https://www.youtube.com/@AmandaPharmD/search?query=naplex
• All calculations (A great place for video tutorials of all kinds of calculation problems you can run into the exam!): https://www.youtube.com/@PharmaceuticalCalculationsEasy
• Naplex Practice Calculations Questions: https://pdfcoffee.com/naplex-practice-questions-rxcalculations-pdf-free.html
• Alligation: https://www.youtube.com/watch?v=67HX1ZsGoKk
• TPN:
  • https://www.youtube.com/@PharmaceuticalCalculationsEasy/search?query=TPN
  • https://www.tldrpharmacy.com/content/the-total-rundown-on-total-parenteral-nutrition
• RxExam's Biostatistics: https://www.pharmacyexam.com/images/pdf/Biostatistics_Sample_Questions.pdf
• TI30X emulator trial download:
  • https://education.ti.com/en/software/details/en/3e7218fdf3844afeba3885b671191ceb/sda-ti-smartview-ti-30x-ti-34-multiview
  • https://www.passnaplexnow.com/calculator.html
  • https://www.pearsonvue.com/athena/athena.asp
  • https://aldenbradford.com/calculator_emulato

Pharmacology:

• Medicurio → Best video shorts for quick disease/drug review. Animations are great! I like to watch/listen to these while doing other things: https://www.youtube.com/@Medicurio
• Speed Pharmacology: https://www.youtube.com/channel/UC-i2EBYXH6-GAglvuDIaufQ
• Ninja Nerd: https://www.youtube.com/channel/UC6QYFutt9cluQ3uSM963_KQ
• Dirty Medicine → Great pharmacology info: https://www.youtube.com/watch?v=cI8G2KSQdMo&list=PL5rTEahBdxV6kvrOR0aL9Su4V40OJs8LH&pp=iAQB
• TonyPharmD → Great pharmacology mnemonics: https://www.youtube.com/@TonyPharmD/search?query=pharmacology
• Pyrls → If you make an account it has lots of good visual charts for various disease states. However, some charts may require payment for pro-membership. The first link is for the application. The second link is for the free 2024 charts: https://app.pyrls.com/home and https://firebasestorage.googleapis.com/v0/b/pyrls-prod.appspot.com/o/contentPDFs%2Fpyrls_charts-bundlev3-1.pdf?alt=media&token=b2ecf70a-fe8a-4329-9be4-d7f33b41f5c7

HIV Info → RxPrep has WAYYYY too much info on this than you need and doesn't simplify it in a way that is great for studying for the Naplex, especially for memorizing brand/generic. However, it is still a very popular topic that Naplex likes to test on most exams. Please use the following link to guide you on how to approach studying the HIV section: https://www.reddit.com/Naplex_Advice/comments/1c61t0l/a_guide_to_hiv_regimen_rules_and_memorization/
Dosing → DO NOT focus your time on memorizing all the dosing except for whatever RxPrep tells you to and the following: hyperlipidemia, hypertension, APAP and IBU dosing (adult vs. pediatric), anticoag, cardiology, and OI prophylaxis
Key Drugs Guy/Study Tip Gal on Quizlets → You can find more flashcards by searching “key drugs guy” and “study tip gal” on Quizlet. I tend to favor key drugs guy most though. I put a couple of them below:

• https://quizlet.com/575387356/key-drugs-guystudy-tip-gal-flash-cards/
• https://quizlet.com/815331657/naplex-key-drug-guy-flash-cards/

Compounding → Both RxPrep and PNN are very basic info, but not very detailed. You would need to be more thorough when studying for MPJE. You should focus most of your attention to “The Basics” compounding chapter in RxPrep, stability and degradation, excipients (some patients cannot have certain excipients due to their disease state), hazardous drugs (be able to recognize them), BUD, garbing, cleaning/spills, storage, and documentation

• https://www.wolterskluwer.com/en/expert-insights/usp-797-translating-low-medium-and-high-risk-compounding-into-categories
• https://eagleanalytical.com/bud/
• https://eagleanalytical.com/facility-design/
• https://www.youtube.com/@EscoTaPestleRx/videos
• https://healthcare.contecinc.com/usp-797-compliance-in-proper-donning-of-garb

Other Useful Communities → If you have recently passed either the Naplex or MPJE, I am looking for contributors/mods/members to share their insight on their experiences in the communities below. If you are interested in being a mod, please DM me!

• Pharmacy Students → This is a community-based group meant to help students with their studies during school and provide advice/insight to rotations and pharmacy in general: https://www.reddit.com/Pharmacy_Students/
• Naplex Advice → This is a community-based group meant for students and recent graduates to help each other prepare for Naplex. One of our mods also offers one-on-one tutoring sessions as well. And yes, the Prozac banner was intentional! lol: https://www.reddit.com/Naplex_Advice/
• MPJE Advice → This is a community-based group meant for students and recent graduates to help each other prepare for MPJE. It is there to make looking for state-specific and federal resources easier to find, with the help those who have already passed: https://www.reddit.com/MPJE_Advice/
• 💊 PharmaPrep Discord 💊 → Are you striving for success in your pharmacy career? Feel like you need a little extra help to make your dreams a reality? Join PharmaPrep, the exclusive Discord server that's your one-stop destination for all things pharmacy! Our community is more than just a study server; it's a network of aspiring pharmacists and seasoned tutors, all dedicated to helping you excel. Whether you're a fresh-faced student or a graduate on the cusp of your career, PharmaPrep aligns with your goals. Follow this link to get the invite: https://discord.com/invite/CVCTJPcVz8
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 **Why do people believe Lyme is Fake?** 

The skepticism surrounding Lyme disease, particularly chronic Lyme disease, stems from a combination of factors including diagnostic challenges, variability in symptoms, and differing medical opinions. Here are some key reasons why some people may doubt or question the legitimacy of Lyme disease:

1. Diagnostic Challenges: Lyme disease can be difficult to diagnose. The symptoms are diverse and often mimic those of other conditions, leading to misdiagnosis. Additionally, current diagnostic tests are not always accurate, especially in the early stages of the infection.
   
2. Lack of Consensus on Chronic Lyme Disease: There's significant debate within the medical community about chronic Lyme disease—a condition reported by some patients who experience persistent symptoms after treatment for Lyme disease. Some medical professionals question the existence of chronic Lyme disease due to a lack of conclusive evidence showing persistent infection with the Borrelia burgdorferi bacteria after standard treatment.
   
3. Variability in Treatment Responses: People with Lyme disease can have vastly different responses to treatment. While many recover with standard antibiotic therapy, others report lingering symptoms. This variability contributes to skepticism, particularly when standard medical treatments do not resolve the patient’s symptoms.
   
4. Misinformation and Misunderstanding: Misinformation online and in social media can contribute to misunderstandings about Lyme disease. Stories of misdiagnosis or claims of miraculous cures may lead some to question the legitimacy of the disease or the medical community's understanding of it.
   
5. Medical Controversy: The controversy among doctors over the best approach to diagnose and treat Lyme disease, including the use of long-term antibiotics for those claiming to have chronic Lyme disease, has led to public confusion and skepticism.
   
6. Symptom Overlap with Other Conditions: Lyme disease symptoms overlap with many other chronic conditions, such as fibromyalgia, chronic fatigue syndrome, and autoimmune diseases. This overlap can lead to skepticism about Lyme disease as a distinct condition.
   

It's important to rely on credible sources and evidence-based medicine when seeking information about Lyme disease. The recognition of Lyme disease by major medical institutions and ongoing research aims to improve understanding, diagnosis, and treatment, helping to address skepticism and improve outcomes for those affected.

 **Why do people think Lyme that isn’t recognized or diagnosed shortly after acquisition should be easily treated after the person has had it for months or years?** 

The belief that Lyme disease should be easily treated, even if not recognized or diagnosed until months or years after infection, may stem from several misconceptions and a lack of awareness about the disease's complexity. Here are some factors contributing to this belief:

1. Underestimation of Disease Complexity: Some people may not fully understand the complexities of Lyme disease, especially its ability to mimic other conditions and the potential for the bacteria to disseminate and hide within the body. This lack of understanding can lead to the assumption that, like some other bacterial infections, it can be easily treated with antibiotics regardless of how long the infection has been present.
   
2. Misinformation: Misinformation about Lyme disease is widespread, including overly simplistic views on treatment. People may read anecdotal stories online about quick fixes or miracle cures and come to believe that late-stage Lyme disease should be no more difficult to treat than early-stage disease.
   
3. Limited Public Awareness: Public awareness campaigns often focus on prevention and the importance of early treatment, which is crucial. However, this may inadvertently contribute to the perception that if Lyme disease is caught and treated early, it's a minor concern, implying that later treatment should also be straightforward.
   
4. Varied Individual Responses to Treatment: Individual responses to Lyme disease treatment can vary significantly. Some people may experience quick and complete recovery with antibiotics, even if the disease was not immediately diagnosed. These success stories can contribute to the belief that late-stage treatment should always be straightforward.
   
5. Confusion About Chronic Lyme Disease: The debate within the medical community regarding chronic Lyme disease—where symptoms persist after standard treatment—may lead some to oversimplify the disease's treatment at any stage. People might not appreciate the difference between treating an active infection and managing the lingering symptoms that some attribute to chronic Lyme disease.
   
6. Overlooked Complications: Late diagnosis and treatment of Lyme disease can lead to complications, as the bacteria might have caused more extensive damage to the body's systems. This complexity requires more nuanced treatment approaches, which can be overlooked in simplified narratives about the disease.
   

In reality, treating Lyme disease that has been present for months or years can be challenging. It may require a multifaceted approach beyond standard antibiotic treatment, including managing symptoms and addressing complications. The belief in easy treatment reflects a need for increased education and awareness about Lyme disease's potential severity and complexity.

 **Why do people not believe chronic Lyme or post treatment Lyme is real?** 

Skepticism about chronic Lyme disease or post-treatment Lyme disease syndrome (PTLDS) arises from a combination of factors related to diagnostic challenges, the nature of symptoms, and differing views within the medical community. Here's why some may question the reality of these conditions:

1. Lack of Consensus in the Medical Community: There's significant debate among healthcare professionals about the existence of chronic Lyme disease. While some practitioners recognize it as a condition that requires long-term treatment, others are skeptical due to the lack of clear diagnostic criteria and conclusive evidence of ongoing infection with Borrelia burgdorferi after the initial treatment.
   
2. Diagnostic Challenges: Both chronic Lyme disease and PTLDS lack specific, universally accepted diagnostic tests. The symptoms are often nonspecific (such as fatigue, joint pain, and cognitive issues) and overlap with many other conditions, making it difficult to definitively attribute them to Lyme disease after standard antibiotic treatments have been completed.
   
3. Variability of Symptoms: The wide range of symptoms and their fluctuating nature can lead to skepticism. Since these symptoms can also occur in numerous other conditions, some medical professionals and laypeople may doubt their connection to a past Lyme disease infection.
   
4. Misunderstanding of Bacterial Infections: Some people might not fully understand how bacterial infections work, particularly the idea that some infections can cause long-lasting effects on the body, even after the bacteria are no longer detectable. This can lead to skepticism about the validity of chronic conditions attributed to such infections.
   
5. Controversy Over Treatment Approaches: The treatment for chronic Lyme disease often involves long-term antibiotic therapy, which is controversial and not widely endorsed by major medical organizations due to concerns about antibiotic resistance, side effects, and the lack of evidence supporting its efficacy for this purpose. This controversy contributes to the skepticism.
   
6. Information and Misinformation: With increasing access to information online, people encounter a wide range of perspectives and experiences related to Lyme disease. While this can be beneficial, it can also lead to confusion and skepticism, especially when faced with contradictory information or anecdotal evidence lacking scientific backing.
   
7. Scientific Evidence: The skepticism is partly due to the current state of scientific evidence. Major health organizations like the CDC and the Infectious Diseases Society of America recognize PTLDS but note that its cause is not well understood, and there's no proven treatment. The lack of solid evidence for chronic Lyme disease as a distinct condition fuels skepticism.
   

Efforts to increase awareness, conduct research, and develop clear diagnostic and treatment guidelines may help address skepticism about chronic Lyme disease and PTLDS, improving understanding and support for those affected.

 **Why do people think that Lyme is easily treated with a few weeks of antibiotics?** 

The belief that Lyme disease can be easily treated with a few weeks of antibiotics stems from several factors, primarily based on the standard treatment guidelines for early-stage Lyme disease and the general characteristics of bacterial infections. Here's why this perspective exists:

1. Early Detection and Treatment Success: When Lyme disease is diagnosed early, a short course of antibiotics, typically doxycycline, amoxicillin, or cefuroxime, is often highly effective in clearing the infection and preventing further health complications. This success has led to a generalization that all Lyme disease cases can be easily treated if identified promptly.
   
2. Guidelines from Health Organizations: Major health organizations, including the Centers for Disease Control and Prevention (CDC) and the Infectious Diseases Society of America (IDSA), recommend a 2-4 week antibiotic treatment for most cases of Lyme disease. These guidelines are based on extensive research and clinical trials, reinforcing the belief that short-term antibiotic therapy is sufficient for treating Lyme disease.
   
3. Understanding of Bacterial Infections: Generally, bacterial infections are known to be treatable with antibiotics. The public's understanding of antibiotics as a cure-all for bacterial infections contributes to the expectation that Lyme disease, caused by the bacterium Borrelia burgdorferi, should be no different.
   
4. Simplification of Complex Information: The nuances and complexities of Lyme disease treatment can be lost in simplified messages conveyed by media or even in healthcare settings. This can lead to an oversimplified view of the disease's treatment among the general public.
   
5. Underestimation of Chronic Lyme Disease: There's ongoing debate and skepticism within the medical community about the existence and nature of chronic Lyme disease or post-treatment Lyme disease syndrome (PTLDS), where symptoms persist after the completion of antibiotic treatment. The controversy and lack of consensus contribute to the perception that Lyme disease, as a rule, is easily treatable and manageable with a short course of antibiotics.
   
6. Anecdotal Evidence: Personal stories and testimonials about quick recovery from Lyme disease with antibiotics can reinforce the belief in their efficacy. However, these stories may not fully represent the diversity of Lyme disease experiences, especially more complicated or chronic cases.
   

While a short course of antibiotics is often effective for early-stage Lyme disease, it's important to recognize that the disease can present complex challenges, including persistent symptoms for some individuals, and may require a more nuanced approach to treatment and management. Education and awareness are key to understanding the full spectrum of Lyme disease and its potential impacts on health.

 **Why do people think that testing for Lyme is accurate and stand strongly by this face when there are many places currently trying to make better diagnostics available?** 

The perception that current Lyme disease testing is highly accurate and the strong confidence some people place in these tests may stem from several factors, despite the acknowledged need for improved diagnostics. Here's why this belief persists, alongside efforts to develop better testing methods:

1. Guidelines and Recommendations: Health organizations, including the Centers for Disease Control and Prevention (CDC), recommend a two-tiered testing process for Lyme disease, which involves an initial enzyme immunoassay (EIA) or immunofluorescence assay (IFA), followed by a confirmatory Western blot test if the first test is positive. These recommendations can lead to a perception of reliability and accuracy in the established testing protocols.
   
2. Lack of Awareness About Limitations: The general public may not be fully aware of the limitations of current Lyme disease tests, especially regarding their sensitivity in the early stages of the disease. The tests are most reliable a few weeks after infection, once the body has had time to produce antibodies, and their effectiveness can vary depending on the timing of the test.
   
3. Success Stories: People who receive a timely and accurate diagnosis of Lyme disease based on the current testing methods may stand firmly by the accuracy of these tests, based on their personal experience. Success stories can overshadow cases where the disease was not accurately diagnosed due to testing limitations.
   
4. Simplicity and Accessibility: The current testing methods are relatively straightforward and widely available, making them the standard approach for diagnosing Lyme disease. This accessibility contributes to the perception that the tests are sufficient for most cases.
   
5. Efforts to Improve Diagnostics: The ongoing efforts by research institutions and companies to develop better diagnostics for Lyme disease highlight the recognized need for improvement. However, until new methods are validated and become widely available, the medical community and the public may rely on and defend the existing tests.
   
6. Confirmation Bias: Some healthcare providers and patients may exhibit confirmation bias, giving more weight to test results that confirm a suspected diagnosis of Lyme disease and less to those that don't, especially in areas where Lyme disease is common.
   

Despite these factors, there is a growing recognition of the need for better diagnostic tools for Lyme disease, particularly tests that can accurately detect the disease in its early stages, differentiate between active and past infections, and provide more reliable results for cases suspected of chronic Lyme disease or post-treatment Lyme disease syndrome (PTLDS). Research in this area continues to evolve, with the aim of offering more accurate, reliable, and timely diagnostics to improve patient care and outcomes.

 **Why do people not have awareness of how complex healing from Lyme is, especially considering the other diseases one tick can have and spread in one bite?** 

The lack of widespread awareness about the complexities of healing from Lyme disease, including the potential for co-infections from a single tick bite, can be attributed to several factors:

1. Public Perception and Education: General public health campaigns often simplify messages for broader understanding, which can unintentionally minimize the complexity of Lyme disease and its treatment. While effective for prevention, such simplifications may not fully convey the challenges of diagnosis, the risk of co-infections, or the variability in treatment responses.
   
2. Variability of Symptoms: Lyme disease and its co-infections can present a wide array of symptoms, mimicking other conditions and making diagnosis challenging. This variability can lead to underdiagnosis or misdiagnosis, contributing to a lack of understanding about the disease's complexity.
   
3. Co-Infections Underrecognized: Ticks can transmit multiple pathogens besides Borrelia burgdorferi (the bacteria that causes Lyme disease), such as Babesia, Anaplasma, Ehrlichia, and Powassan virus. However, public awareness campaigns and even some medical professionals may not always highlight the possibility of these co-infections, which can complicate treatment and recovery.
   
4. Debate Within the Medical Community: There's ongoing debate among healthcare professionals regarding the best approaches to diagnose and treat Lyme disease, particularly chronic manifestations of the illness. This debate can lead to mixed messages about the disease's complexity and the healing process.
   
5. Media Representation: Media coverage may focus on acute Lyme disease cases and prevention methods, with less attention on chronic Lyme disease, post-treatment Lyme disease syndrome (PTLDS), or the impact of co-infections. This can shape public perception, underrepresenting the complexity of the condition.
   
6. Personal Experience and Anecdotal Evidence: Individuals who have not personally experienced Lyme disease, or who have only encountered uncomplicated cases, may base their understanding on limited or anecdotal evidence, overlooking the disease's potential complexity.
   
7. Scientific Research and Funding: The complexity of Lyme disease and its co-infections requires significant scientific research to fully understand. However, research and funding may be limited compared to other diseases, slowing the dissemination of new findings and understanding to healthcare professionals and the public.
   

Increased education and awareness efforts, aimed at both the public and healthcare providers, can help improve understanding of the complexities of Lyme disease, including the importance of considering co-infections in diagnosis and treatment. Highlighting personal stories of those affected, along with advancing research into all aspects of tick-borne diseases, can contribute to a more nuanced understanding of the challenges in healing from Lyme disease.

 **Why is the online discourse on Lyme more passionate and contentious than any other infections disease?** 

The online discourse on Lyme disease is notably passionate and contentious due to several unique aspects of the disease and its treatment, societal impact, and the challenges faced by patients. Here's why the conversations about Lyme disease can be more intense compared to other infectious diseases:

1. Diagnostic Controversy: Lyme disease, especially in its chronic form, poses significant diagnostic challenges. The standard tests can produce false negatives, leading to underdiagnosis or misdiagnosis. This ambiguity fuels debate and personal stories of suffering and misdiagnosis, intensifying online discussions.
   
2. Disagreement on Treatment: There is substantial disagreement within the medical community regarding the treatment of Lyme disease, particularly chronic Lyme disease or post-treatment Lyme disease syndrome (PTLDS). The efficacy and appropriateness of long-term antibiotic treatments are hotly debated, dividing both medical professionals and patients.
   
3. Symptom Overlap with Other Conditions: Lyme disease symptoms overlap with many other chronic conditions, such as fibromyalgia, chronic fatigue syndrome, and autoimmune diseases. This overlap complicates diagnosis and treatment, leading to passionate advocacy and discourse from those affected.
   
4. Patient Advocacy and Activism: The Lyme disease community includes highly vocal advocacy groups and individuals pushing for greater recognition of the disease, improved treatment options, and more research funding. Their efforts often clash with established medical opinions, fueling contentious exchanges online.
   
5. Personal Stories of Suffering: Many individuals with Lyme disease share their prolonged experiences of suffering, misdiagnosis, and treatment challenges. These personal stories, often shared online, can evoke strong emotions, driving passionate advocacy and sometimes contentious interactions with skeptics or medical professionals adhering to different viewpoints.
   
6. Limited Public and Medical Education: Misunderstandings about Lyme disease are widespread, partly due to limited public and medical education on its complexities. This gap in knowledge can lead to dismissive attitudes towards those suffering from the disease, further intensifying online discourse.
   
7. Perceived Neglect by the Medical Establishment: Some individuals and groups feel that Lyme disease has been neglected or minimized by the medical establishment, leading to a sense of injustice and a strong drive to advocate for change. This perception contributes to passionate, sometimes contentious, advocacy efforts.
   
8. Impact of Social Media: Social media amplifies the contentiousness of Lyme disease discourse by providing platforms for instant, widespread dissemination of information and opinions. The echo chamber effect of social media can intensify divisions and passionate arguments.
   

These factors combine to make the online discourse surrounding Lyme disease uniquely passionate and contentious. Understanding the complexities of the disease, acknowledging the diverse experiences of those affected, and promoting respectful, evidence-based discussions can help mitigate the contentious nature of these conversations.

** Why are there so many passionate trolls online who want to discredit the research around Lyme, the specialists, and the patients?** 

Online discourse about Lyme disease and other controversial health topics can attract passionate responses, including trolling and attempts to discredit research, specialists, and patients. This phenomenon can be attributed to several factors:

1. Anonymity and Polarization: The internet allows for anonymity, which can embolden individuals to express extreme views or engage in trolling without fear of repercussions. Health topics, particularly those with varying opinions and research, like Lyme disease, can become polarized, leading to passionate and sometimes aggressive exchanges.
   
2. Misinformation and Confirmation Bias: The vast amount of information available online includes both accurate, research-backed data and misinformation. Individuals may selectively seek out information that confirms their existing beliefs (confirmation bias) and discredit opposing views, leading to passionate defense of their stance and attacks on conflicting information or experiences.
   
3. Lack of Consensus in the Medical Community: The ongoing debate within the medical community about aspects of Lyme disease, such as its chronic forms and appropriate treatment protocols, can be mirrored and amplified in online discussions. Individuals may align with one perspective and become hostile towards opposing views.
   
4. Emotional Investment: For some, discussions about Lyme disease are not purely academic or scientific but deeply personal, tied to their own experiences or those of loved ones. This emotional investment can heighten the intensity of their responses, sometimes leading to aggressive tactics against perceived threats or disbelief.
   
5. Skepticism Towards Medical Authorities: A general skepticism or distrust towards medical authorities and the pharmaceutical industry can fuel efforts to discredit mainstream research and recommendations. This skepticism can be exacerbated by individual negative experiences with the healthcare system.
   
6. Identity and Community: For some individuals, their stance on controversial health topics becomes part of their identity and their participation in like-minded communities. Attacks on their views, or the research and specialists they support, can be perceived as personal attacks, prompting aggressive defense mechanisms.
   
7. Influence of Advocacy and Interest Groups: Advocacy groups and individuals with vested interests in certain treatments or perspectives on Lyme disease may engage in discrediting opposing viewpoints to promote their agenda, which can include trolling and other online harassment tactics.
   

Navigating online discussions about Lyme disease and other contentious health topics requires critical thinking, empathy, and the recognition that behind many passionate exchanges are real people with genuine concerns. Encouraging respectful dialogue, relying on evidence-based information, and acknowledging the complexity of Lyme disease can help foster a more productive and less confrontational online environment.

Day 23 of PEP and started having flu symptoms (fever, sore throat, coughing, etc.) so went to doctor next day.
Tested positive for covid and was diagnosed with a case of "covid pneumonia" due to the cough in my chest and fever etc.
Now I am on PEP and having to take a huge Augmentin (amoxicillin) and Medrol pill 2x a day as well.
I didn't find any interactions between my PEP meds and amoxicillin/medrol but holy sh*t I am taking a lot of heavy drugs right now and hope nothing bad happens/I'm not doing any long term damage to my body.
Any advice/tips would be very welcome right now. Thanks.
UPDATE: tested negative for HIV (4th gen) 2 days ago, which was 43 post exposure and 15 days post PEP. Will test again at 90 days.

Hey guys,
I just wanted to share a few thoughts about the influence of our psyche on CPPS. I'm currently doing my Major in Psychology and I struggled with CPPS for the last few months. Similar issues, ruled out everything and anything until my urologist finally told me that he has a few patients every day that he diagnoses with CPPS and that this is NOT something to be treated by a urologist.
What I did to overcome my CPPS: Stretching, yes, pelvic floor therapy, yes, but most of all: Let go.
What I would advise anyone on here who struggles with rather mild or moderate symptoms of CPPS as I did: Just leave this sub. Yes, that's right. CPPS, in my experience, is heavily connected to overthinking, obsessing over autonomous bodily functions that we, for the first time ever most likely, actively observe when we struggle with CPPS.
Was that a weird twitching sensation in my bladder? Probably cancer.
Was that weird burning feeling in my urethra? Probably urethritis.
Was that a weird feeling when ejaculating? Probably prostate cancer - whatever.
As soon as you rule out all these major complications (which, most likely, you won't have if you suffer from CPPS, statistically speaking), get a urine culture done etc., you should just do one thing - let go. Let your body return to its normal state and stop obsessing. That's easier said than done. I know. But you have to do it.
In my case, I started to struggle with rather heavy health anxiety from the time I had some blood coming out of my penis after ejaculating (actually already when I had ACL surgery a few years ago, I know that I can be obsessive in these things since then). For me, it was a muscular reason that I got prostatitis, I cramped too much after a long time of sitting and sexual abstinence. Then things started to go downhill. Urologist did what all urologists do: do their thing, but don't look at any bigger picture at all. Without a moment's hesitation he prescribed me Amoxicillin. Heavy antibiotics for two weeks which fucked my intestines and my psyche, daily and hourly obsessing over my body, my prostate, everything, for weeks I was a mess. Then I went to the doc again - symptoms were better, after all, and every single test came back negative. Then he said one sentence, which triggered this whole wave of anxiety in me once again: "You did have blood in your urine once. We should do a cystoscopy JUST TO BE SURE." Needless to say, a few days later it was the first time that I EVER started to notice symptoms in my bladder area. Dreamt about having cancer and what not. 6 long weeks until my cystoscopy, 6 weeks of obsessing and struggling with health anxiety and obsessive thoughts.
Then, of course, cystoscopy came back with nothing suspicious to be found whatsoever - I felt relieved and symptoms went away (albeit for a few days peeing hurt terribly, which is pretty common after a cystoscopy).
THEN, once again, I started to notice symptoms. Random symptoms: I noticed some discharge coming out of my penis. Freaked out, thought it was an infection. I researched (again) way too much, called the doc, got on antibiotics again. Then, finally, urine culture was NEGATIVE again. But what about the discharge? Doc said it can commonly happen with CPPS, and that one time he finally diagnosed me, I finally felt relieved. The discharge continued, but it was likely a bodily counter reaction to the cystoscopy, which was, to say the least, incredibly uncomfortable. What do you expect when someone shoves a big camera down your urethra? I had never felt so violated before.
I immediately made an appointment with a pelvic floor specialist and started doing more stretching. I came to believe that my OCD / anxiety like behavior likely caused almost every single symptom I ever had, with the exception of this one time I actually had blood coming out of my penis (which was, as I said, very likely due to a muscular reason). Discharge stopped after 1-2 weeks (which still felt so weird to have it that long).
Stop obsessing. Stop researching too much. Do your tests, if you need to, but if you're like me, you probably think:
"But what if I am that 1% that actually has cancer?"
Get it checked out if you really need to. But then, finally, calm down. You're going to be fine. Overthinking makes everything worse. I do not think much about CPPS anymore. Don't even stretch a lot anymore. It's all been in my head - I can't speak for everyone, but I strongly suspect there is a connection between obsessing and symptom severity.
Ask yourself: Do I obsess too much? Research every little thing? Keep an eye on my body 24/7? If you're like me, you do, and that makes all the difference.
Best thing you can do is probably go to psychotherapy and learn how to calm your mind down. Meditation, paradoxically, made my symptoms worse. Why? Because I observed my body, but I was not equanimous. I paid attention but at the same time worried too much.
In conclusion, I just wanted to say, there definitely IS a link between your mental state and your CPPS symptoms. You can only fully get rid of it if you're aware of the root cause, which, in my opinion, is very likely due to psychological reasons and obsessive thinking / anxiety in the majority of cases. Not in all, and of course there is an interaction taking place. But still - really try to actively let go. Do your thing, go out, live your life, and you will see that once you stop worrying all day long, things will surely improve in the majority of cases.
A book I read that I found really interesting: The Myth of Normal. The mind and the body are so strongly linked, things like CPPS are only the tip of the iceberg. Many chronic diseases stem from stress, grudges we hold, from anger issues and many other mental causes. Let go of your obsession, and your CPPS will improve.

Hi!
I have a giant ear infection and just received my antibiotics today (amoxicillin) and I haven’t been able to sleep in days due to the pain. I found today that Motrin helps me a TON and I was wondering if there are any known interactions between NyQuil and Motrin? The NyQuil helps allievate my cold symptoms that caused this infection but the Motrin helps with the pain so much

24F
Hello I’m currently in Spain and having not only a spine flare up but some sort of sinus fever issue going on. About a week ago I was prescribed amoxicillin potassium clauvanate for a reoccurring sinus infection. The dosage instructions was 2xday for 10 days - I was doing good but only taking it once a day and my symptoms got significantly better. However I haven’t taken the dose in 3 days and got a fever yesterday and today accompanied by a wet cough and runny nose. I’ve been taking Tylenol extra every 6h to keep the fever down, however at night it doesn’t seem to do well. I also am taking propalcof (dextramethorpan hydrobromide) with enanadol 25 (Dexketoprofen) for my back pain. I found no interactions with amoxicillin and any of the other drugs except the enanadol. I’m wondering if I should start up the antibiotics again tomorrow morning even though I found one interaction between those drugs saying “Dexketoprofen may decrease the excretion rate of Amoxicillin which could result in a higher serum level” - yet I have no idea what that means. Any advice is welcome thank you.

21 Male 6'1 220 lbs non smoker medications: escitalopram azithromycin allegra. So around Christmas time I had RSV which subsequently turned into a sinus infection. My GP prescribed me a 5 day course of azithromycin as I'm allergic to amoxicillin. I also take escitalopram 10mg for anxiety. On my second day on antibiotics I tested positive for Covid which was a bit of a knockout combination. Since last night my resting heart rate has been much higher sitting around 85-100 when it is normally in the low to mid 60s. I know there is a possible interaction between escitalopram and azithromycin but my pharmacist said it was okay to take. I'm just not sure if it is the Covid causing my heart rate to increase of the antibiotics. I also have a history of PACs less than 1% burden if that makes any difference. I just want to make sure my heart is doing okay. Any advice would be appreciated

Hey, just got prescribed amoxicillin for a tooth infection that I’m picking up from the pharmacy later today but when I googled it in that drug interaction website it said there was a major one between the two and now I’m really concerned? My last dentist gave me penicillin which doesn’t have any.
Should I be trying to get the doc to change it?

Symptoms and life: I was really struggling 2019-2022. Sleep was just not right and I never felt rested. Lots burping and nausea. Morning abdomen aches, constipation, and poor appetite. Waking up felt awful. Brain fog, difficulty breathing. Whenever I tried to fight myself into doing more, the walls around me just got higher. Terrible cycles of fatigue, likely caused by interactions between the bacteria and diet. I was not enjoying anything I usually enjoyed. I was struggling to do small chores like helping cook or clean.
2023 1st treatment: Prior to this I had seen at least 10 doctors trying to figure out what was wrong. I tested positive early 2023 and a doctor who I will call “Doctor Z” put me on a 2 week omeprazole and amoxicillin dose. I get mostly no side effects except a weird taste and some nausea, but I still have the aforementioned symptoms. He didn’t bother re testing during our follow up. I went literally down the street for a second opinion gastroenterologist. Gastro doctor was super pushy but did find H pylori still there.
2023 2nd treatment: gastro doctor put me on amoxicillin and omeprazole again. Follow up, of course tested positive, the bacteria is still there. Gastro doctor prescribes quad therapy, omeprazole, tetracycline, metronidazole, bis subcycilicate. This therapy messed me up, especially the metronidazole, almost couldn’t eat it without puking. I couldn’t keep up with the schedule and missed doses. I took ginger tea, and some vitamin D (I did have a vD deficiency). Somehow even after missing like 3-5 doses and over half the bismuth sub, I go in for a follow up and test is negative.
2023 post Quad therapy: Still getting those morning stomach problems and constipation. Stool is very unusual, fluffy and completely not together. So I pick up a probiotic 90 tablets for 90 days. Slowly but surely a worlds difference. Breathing easier, no more morning cramps, I figured out some of my symptoms were from dry climate (less saliva to digest food). Eating is still a precarious matter. Outside street food and restaurants are out of the question, almost always get diarrhea afterwards. Stool is mostly normal and clumped together now but still looks a bit off. Bits of dark, seemingly undigested stuff. Don’t know if I need a stool test.
Tl:dr. Constant fatigue, nausea, brain fog for 3 y. 10 docs over 3 yrs + therapy, no results. Test positive but first doctor gaslights me. Quad therapy big toll, but probiotics help.

Caucasian female, 31 years old, 315lbs, non smoker, seldom social drinker.
3 weeks ago I went to the ER because I thought I had a blood clot. My lower right calf was extremely painful to the touch and red. Had an ultrasound done with no DVT findings. Was diagnosed with cellulitis and given Clindamycin. 3 days later, I noticed the pain and reddness were tracking up my leg, following a path of a vericose vein that I have. I went to urgent care thinking my antibiotics needed to be changed - was diagnosed with superficial thrombophlebitis and was then sent back to ER who gave me the official diagnosis and gave me bactrim instead. Did the full 10 days of bactrim and had about a 2 day break from pain. I saw a family medicine doc in between who told me to elevate leg and wear compression socks. After my 2 day pain break, I noticed I had the same pain starting at my knee crease and going up my thigh, still following the vericose vein track. I contacted a virtual doctor who advised me to continue warm compresses and take ibprofen 600mg 3x/day. 3 days after that I went back to ER because the reddness was still traveling up my thigh. They admitted me for IV antibiotics starting Sunday night and ending Tuesday night. They did a CT of my legs and found cellulitis, another ultrasound with no findings of DVT. my reddness continued to grow at a slower pace at the hospital. They said my white blood count was showing improvement as well as the test they did to show my blood reacting to the inflammation? Which was also improving so they sent me home on amoxicillin. My concern is that being home, the redness is still growing. Why? No one seems to be able to tell me why. Or show any sort of confidence that it’s going to stop eventually. And if it doesn’t stop, when do I be concerned? Just looking for some insight! Sorry for the long story. I have plenty of progress pictures if needed.

My 18m son was diagnosed with a double ear infection and was prescribed amoxicillin. In my panic, I didn’t ask the pediatrician if it can be mixed into food/drinks but I’ve done some googling and I can’t find a solid answer.
My son will absolutely NOT take medication straight. No syringe or spoon or medication pacifier will get it done, he clamps his jaw shut and if I do manage to get medicine in, he just spits it out. So, we have to be able to hide it. My go to have been fruit pouches, but I’m worried that somehow the interaction between amoxicillin and fruit is causing the antibiotic to be not as effective. I also saw inconclusive results about yogurt/dairy.
Am I being overly anxious? Is there truth to the interaction cautions? If so, what else can be tried to hide the amoxicillin?
Any help is appreciated, thank you!
article link about antiobiotics and fruit juice/yogurt

This all happened in June 2022 after getting covid-19. Before covid, I was kinda relatively healthy. I had OCD, PTSD, eating disorder, anxiety disorder, depression. And physically, I had normal seasonal allergies on set from giving birth to my only child at 18. As I got a little older, migraines happened due to family history. Everyone gets them in my family. And i suffered some acid reflux that i noticed got worse in 2021, maybe from too much stress? It was weird. I also remember once being really sick for a few months waking up with nausea every day from amoxicillin. This was 2019. But it cleared and I was fine. But then, I got covid. June 2022. First, I suffered heart racing and adrenaline dumps. I would stand or even sit up and my BPM would skyrocket dangerously to 185-190 in my mid to late 20s. After 6 months, this faded but sometimes my bpm goes nuts during anxiety or acid reflux after eating. I remember in August 2022, i was eating a fry and began to itch my neck. I questioned if i had a rash and stood up to check, only to feel like I genuinely was not getting enough air in my lungs. BPM was high. I was gasping on the ground for hours. No rash btw. That night, due to scratching my skin, i noticed onset Of dermatographia. Red skin, imprinted skin, burning upon interacting with the skin in any way. This frightened me a LOT. I also had a horrible situation after covid with a spicy chicken sandwich and waking up to being unable to breathe due to acid getting into my lungs. I suffered the worst acid reflux ever and began taking tums nearly every day. I was very hyper-fixated on the dermatographia and asked long covid reddit groups about it to be met with “sounds like MCAS”. Upon reading about it, I panicked and then only ate foods I had eaten between covid ending and that time where I didn’t have something weird happen like the fry or spicy sandwich dwhich. This led me to only eating wendys normal sandwich whichs, wendys fries, nuggets, cupcakes, chipotle bowls with chicken, rice, cheese, lettuce, and guacamole, coke, and two bite brownies. Yeah. Absolutely awful. After a few months, i added cheese steak too. I had acid reflux with every single meal. But I didn’t care because it wasn’t anaphylaxis and focused more on my skin reactions and itching and weird flaring that kept happening. After MONTHS, i realized my skin was itching was being anxious and leaving the shower too soon and not rinsing my hair all the way, leaving shampoo in it, which explains the neck being the only thing that would itch. In December, itching it would cause neurological symptoms where i itched where it felt like it would go numb. But the weird skin flaring that caused a more inflamed sensation never improved. It wasn’t until I pieced together I kept reacting when my clothes had a particular smell on it. So we changed detergents and i still reacted, as i STILL smelled the same thing. We realized the smell came from our public dryer where someone in our apartment is using harsh dryer sheets. Avoiding it seems to get rid of it? But we are still testing. But then, in spring 2023, things began to worsen. While we were avoiding skin reactions a LOT more frequently (its nearly become a non issue, except we are now considering getting our own dryer to see if we can get to stop entirely). Before spring, i made the choice to axe the guac off my bowls because everyone told me to eliminate high histamine foods, so i did despite it not doing anything apart from what every other food did which was just cause reflux. Like every meal did. the spring hit and then brain fog and ear fullness happened. As well as weird neurological sensations on my face specifically. The brain fog only comes on with severe head congestion. This began to cause me to drink coke and then the ears would fill and i would become brain fogged for say 20 minutes. So i axed it because mcas reddit told me to. In the spring, i also felt acid reflux suddenly worsen where eating the cheese steaks cause my stomach to feel numb and i had to keep burping to relieve it and usually by evening, looked forward to chipotle because it kinda would neutralize the feeling. My lungs would become numb during these attacks and i would frantically run around in a panic scared. I decided to axe out cheese steaks and temporarily, the sensation went away. But came on again in the summer randomly after eating things. In summer too, i got ris of cupcakes after a two time instances of them triggering a migraine. But tbf, i already suffered from chronic migraine. This just made me fear even more that its the mcas boogie man getting me so i axed it. In fall, suddenly every food i had left and even water caused the numbness feeling in my lungs so i panicked and stopped eating everything apart from chicken and rice. It came on so severely and the ear clogging and brain fog happened too.
So a breakdown: Total - All symptoms so far
Dermatographia, has lessened a lot Skin flaring that so far comes from dryer sheets Burning and skin redness when rubbed or interacted at all during flares Itching from shampoo left on skin Neurological symptoms on flared up locations and areas that get scratched GERD - Acid Reflux every day (below symptoms of reflux that i get) - numbness in stomach when i eat (is this reflux? Mucus?) - Shortness of breath - Stomach pain from pressure - Sweating Bloating During heightened allergy season: Extreme congestion in face and head Brain fog when congestion is bad enough Sometimes eating and drinking things cause sudden ear fullness, head congestion, and brain fog. Allergist told me this was due to congestion already existing and eating and drinking causing it to move around while mcas reddit said to ace it, sign of reaction Neurological symptoms on face when congestion in extreme Ears clogging and fullness Skin neurological symptoms, like lack of sensation if skin gets wet or if heat is blown onto skin, lasts for 45 minutes to over an hour (not always, only during skin flares)
I think it could be MCAS .. but I also keep questioning myself over certain things not making sense.
Like how on earth i ate so much junk and didnt get anaphylaxis. Haven’t had it once.
Allergist recently is telling me dermatographia is from a particular antibody from the covid infection but also can be caused from moderna vaccine.
Am i just having a lot happen ? For instances, my seasonal allergies are WAY worse than usual but also LA is having a super bloom and every allergist keeps telling me this is the worst allergy year they’ve seen.
Its a lot and even with chicken and rice, the numbness is here. The only improved symptom is the acid reflux but its not gone either. Its just lessened? But still have days with it that its bad. Still getting brain fog sometimes upon eating and congestion. Fall allergies outside are really bad.
Does everyone with mcas just nearly always have acid reflux? Apart from sometimes?
Please give me your honest input. MCAS?
Asking here because doctors arent helping me

I'm on amoxicillin right now and I really would like some ginseng. Anyone know if there's any adverse interactions between Korean Panax Ginseng and amoxicillin?

Hello everyone, I have strep and I need to take a round of antibiotics (amoxicillin) and I was wondering if I should be worried about taking amoxicillin and Valtrex at the same time. From a quick google search it shows there is no interaction between the two but I wanted to ask on here in case someone has personal experience or knows. Thank you so much!

Just wanted to hear from someone that may have more information than i can find on google. Im currently taking bactrim and tamsulosin for 5 days now but am weary of possible negative interactions with taking some muscimol extract. I know the bactrim is a heavy duty antibiotic. Cant really find a definitive answer on interactions between any of these chemicals.

• Species: Feline
• Age: 9+?
• Sex/Neuter status: Male/Intact
• Breed: Unsure
• Body weight: 11lb
• History: Found outside during a storm almost 6 years ago and brought inside to his forever home. Has always been vocal, had a hypersalivation incident 5 years ago (9 months after arrival) for which ER vet kept him and gave fluids until salivation subsided. Was told at that time that his teeth indicated he was 4-5 years old, and was given vaccinations according to that age.
• Clinical signs: As an intact male he has always had small instances of spraying. Typically on my boyfriends laundry on the floor. His vocalization was also described as a symptom of us not fixing him and perhaps his breed as he has medium-long grey hair with a white undercoat. Never had breed testing done. During a busy work week he began having more non-productive puke (aka, no food or hairballs, just watethick saliva) within 48 hours of admittance. Came home late one night to find him squatting in his box without any production, a hyper focus on grooming his genitals, then squatting in unusual places such as the end of my bed. He did not attempt to move when jostled or startled, so we took him in.
• Duration: 24-48 hours for the most intense symptoms.
• Your general location: Minnesota
• Links to test results, vet reports, X-rays etc. : Vet diagnosed FLUTD/FIC. Emergency vet quoted 5k to clear the blockage and keep him for 48 hours. We asked that the vet clear the blockage so we could take him to another vet in the morning. The ER vet provided a pre-cath urine sample and a sample of the "plug" or blockage. They wanted those samples refrigerated but upon arrival at the morning vet we waited for around 4.5 hours with the samples. (I did try to ask them multiple times to take the samples to keep them cold but felt ignored.) They were unable to get any analysis off of the blockage but found "some" crystals in his pre-cath urine. Vet gave us outpatient treatment with a course of 4 seemingly strong drugs, 1 of which causes hypersalivation.

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My question is about the course of treatment for my cat with FIC/FLUTD. He is intact so he has always had some quirks. 3 of these meds are given every 12 hours (2x per day) and the other 1x per day. They are; Amoxicillin, Buprenorphrine, Acepromazine, and Amitriptyline. There is no recommended spacing or timing for these meds, but there is the factor that we have to work so most of these meds can only be given within a couple hour timeframe (if given 2x per day) where we are realistically there and able to give it "on time."I'm also super nervous about giving him the hypersalivation med (Amitriptyline) due to his past.
So we gave him the 3 the other day and he couldn't even keep his balance and was so out of it and likely to hurt himself that one of us had to call out of work to keep an eye on him. We now feed him prescription royal canin ur+calm exclusively and he loves it, but I don't wanna keep my baby drugged out unless its necessary. From what I see there is a pain reliever, an antibiotic, and a muscle relaxer + "the one with the side effects". So here are the questions google couldn't answer for me.

1. How do I figure out which meds interact with others, so that I can try to time between these?
2. Is Amitriptyline a normal and necessary drug for blockages in cats? What specifically does it do?