Zoloft and hyperhidrosis

It's been quite a while since I've not been on Lexapro.
It's bad enough I have hyperhidrosis that affects my head, face, shoulders, chest, and back. But some antidepressants apparently have a side effect of excessive sweating.
I was on Zoloft like 10ish years ago, and it made me sweat like crazy. Walking up a short set of stairs in AC, being slightly shy, I'd even sweat in freezing temps. It was so uncomfortable.
With Lexapro, I'm not really sure if it's making anything just slightly above my base HH level? It's definitely better than the Zoloft. I'm fine when I'm in decent temps, and it takes a lot of discomfort for me to start when it's due to anxiety in normal temps/conditions.
But during the summer, I sweat very easily in the heat, especially in humidity whether it's humid outside or due to lots of people in close quarters. I don't think it's the Lexapro? But I'm honestly too afraid to stop the Lexapro to find out

I have bad palmar hyperhidrosis and I’m about to start taking Zoloft. It says hyperhidrosis is a side effect of Zoloft. Has anyone experienced this?

CW // quick mention of suicidal ideation and SH
looking for stories from ppl who started Zoloft as a child!
I’m 20F and was prescribed zoloft at age 8 (started at 25mg, now taking 125mg) for severe anxiety, and panic attacks related to undiagnosed emetophobia/OCD. Idk how to feel about being medicated so young, but it does raise some concerns as I’m getting older.
as I’m looking to the future, I want to have kids within the next few years and would like to not be taking an SSRI while pregnant or trying to get pregnant. I’m concerned though, because I don’t remember life without my meds and I honestly don’t know who I would be without them. I cant even say if the meds are working bc I don’t know any different. I’m unable to connect any negative side effects to the meds (like hyperhidrosis, no libido, no appetite, inability to cry, teeth grinding, sleep talking, depressive episodes, nightmares, etc.) there’s no way to tell if those symptoms are from the Zoloft, a mental illness, or some other physical illness. If I stop taking it, I have NO idea if my panic attacks will increase again, or if I’ll be able to cope with the withdrawal. Idk if the meds are helping with my panic attacks or if it’s the last 5 months of exposure therapy, or maybe both. I also already struggle with SI/SH and have read that stopping meds may increase those things, which is another concern.
I feel like the only way to know if they’re actually helping is to stop taking them. Is this a bad idea considering how long I’ve been taking them? I’m terrified of the discontinuation symptoms (especially the stomach issues), but maybe if I work closely with my GP and/or psychiatrist we can manage the symptoms by taking it super slowly. I also struggle with several other mental illnesses, I wonder if the Zoloft is making those things worse? or maybe a different med would help more or decrease some of the negative side effects (if they’re due to the Zoloft)?
anyone have thoughts? advice? any similar experiences?

Greetings to the team that made me feel like I'm not alone in what I'm going through with my hyperhidrosis. I have to say that it's something I don't feel comfortable discussing even with my friends, let alone the neurologist I visited.
Notes:

• This is not a product advertisement; I'm simply describing my experience. That's why I won't include any links.
• The text was translated from Greek using AI since my English is "poor."

Quick background:

• I am a 48-year-old man who had a heart attack at the age of 35 and has had another serious condition since I turned 36. I mention this to give you an idea of the type of hyperhidrosis I have, as I take quite strong medications. Before the two conditions, I would sweat slightly more than the average person, but that was about it.
• I do not have depression (also confirmed by two different psychoanalysts).
• For the past 10 years, I have been sweating a lot in the dome (shaved head), slightly in the hands and feet, and heavily on my back. However, all of this occurs objectively when it's hot or when I'm physically active. I can handle it. It's manageable.
• However, under my arms, I sweat excessively every day of the year, even in the snow. I don't sweat when I'm alone at home in the winter, but if I have a good friend over for coffee, I start sweating. I only wear black clothing. Some days in winter, with a cotton t-shirt underneath, I "dare" to wear a loosely fitting light-colored shirt on top. Sometimes I regret it…
• Regarding body odor, I have no issues. Even if I apply the mildest deodorant, by the end of the day, I don't smell (thankfully).

What have I done about it:

• Last June (2022), I visited a neurologist who suggested Zoloft. I waited patiently (along with my weight) until May 2023.
• I also tried some specialized antiperspirants (containing aluminum salts), which worked well but didn't solve my problem. The sweat decreased by about 50%, but the remaining sweating still affected my quality of life. Among the products, I tried Certain-Dri and Perspi-Guard, among others.

What I haven't tried:
Botox due to the cost (with repeated sessions), Miradry due to the initial cost, and any invasive methods because I'm afraid.
What finally worked:
About 10 days ago, I tried Purax roll-on as a final non-invasive option. I ordered it from their European store for €18 (with free shipping, although the package traveled through five countries before reaching me in about 12 days).
Although I was very careful with its application to my underarms (using a small amount, applying it shortly before bed on completely dry skin, etc.), my skin got irritated during the first 2-3 applications. However, now it only tingles on the night of application.
I now use it every 4 nights and am slowly considering extending it to every 6 nights.
I live in Athens, where the average shade temperature reaches 34 degrees Celsius. My underarms remain completely dry, even after walking 4 kilometers (I enjoy going for walks with music in the afternoon, always in the shade).
Now, I've stopped changing 4-8 t-shirts per day. Additionally, after many years, I bought some brightly colored t-shirts. As strange or even funny as it may seem, now that I'm writing that I can finally wear any color I want, I'm tearing up.
Result:
Not only am I dry all day (the underarm may get slightly damp, but only under conditions where the rest of the world is excessively sweaty and doesn't face the problem of hyperhidrosis), but my mental well-being has also improved significantly.
What I "fear":

• The possibility of Purax ceasing to work, just like Certain-Dri stopped working for a user in our subreddit after a few months (I read all the posts).
• The potential harm of the product, as some claim that all products containing aluminum salts are harmful. From what I've researched, it hasn't been proven, but they don't have the best reputation, as I read former users mentioning "2 years without such products," etc.

What I don't “fear”:

• The dryness it causes in my underarms. The next morning after application, I use plenty of moisturizer before and after showering.
• Being able to wear any clothing color I want! After approximately 10 years!

Thank you very much for your time. I wanted to be as detailed as possible because I believe that if even one user of our subreddit is helped, it was worth the time to write this post.

I recently started on 50mg per day about two weeks ago to help with my anxiety and sweating issues. Before taking zoloft, I was diagnosed with hyperhidrosis (excessive sweating) and no prescribed deodorants worked. My dermatologist recommended i treat my anxiety to see if that helps.
Well it’s only made everything worse. My hyperhidrosis has now spread to my face and other parts of my body I never used to sweat much in. This mordofies me because I’m going on a work trip to a warmer climate and will need to present/meet a lot of people. I already sweat in anxious situations and I feel like now I’m gonna look like a fool. Should I stop taking Zoloft? Are there any hacks to get around sweating -particularly on the face?

Im a 23 y/o male that wants to share his story to maybe help another person dealing with the same thing as I am.
I have been suffering from severe craniofacial hyperhidrosis since I was about 16. At the same time, I was put on an antidepressant (SSRI Zoloft sertraline) which I've come to find out can cause excessive sweating as a side effect. I want to start the journey of getting off them completely but am not ready yet. I am still dealing with some rough life situations but my ultimate goal is to be 100% medication free. My sweating has continued to present day but I've recently found helpful things to counteract. I told my doctor about the issue and she prescribed me glycopyrrolate (anticholinergenic) that does help tremendously but comes with a fair share of side effects and is very strict as far as absorption. If you take it with anything in your stomach besides water, it will not work. Also you cannot eat anything for about 6 hours before and 1 hour after otherwise it will not absorb and take effect. You can't drink anything besides water for 1 hour before and 1 hour after or it won't absorb. It also takes 4 hours to begin to work after taking. I did some research and found that the reasoning behind sertraline and most antidepressants causing excessive sweating is due to the excess amount of brain chemicals floating (serotonin, dopamine, norepinephrine) and leading to sweating so I thought well what if I add something to help with absorption of those chemicals which lead me to l-theanine, an amino acid that is a precursor to serotonin, dopamine, and GABA and promotes a sense of calmness and relaxation. Every morning after I take my glycopyrrolate, I take 200mg of l-theanine and have found that it helps tremendously with sweating. It also calms me down without making me tired. I love it so far and its literally been my life saver as I just started a new job. Someone please try this out and tell me if it's only me experiencing this!!! L-theanine is expensive. It's about $15-$30 a bottle but is worth every penny in my opinion!!

Hey guys, I'm a 21 year old female. I do have hyperhidrosis. I'm not on the pill, I used to be until 3 months ago and the same with accutane, was on it for a few years until 3 months ago. I am currently on zoloft and have been for just under 2 months now. My symptoms are as follows;

• Intense wrinkling of my hands within minutes of being in the bath or shower, this causes some peeling of skin as well and is overall uncomfortable
• Tiny petechiae dots on my lower legs up to the inner corner of my knees
• Mild dyshidrosis on hands that flare every now and again
• fatigue/no energy
• Recurrent mouth ulcers
• keratosis pilaris on legs suddenly a year ago, also when I stand for around 5-10 minutes or more my legs look more reddish and it disappears when I sit down or elevate them

I have had my blood pressure tested, its fine. I've had a platelet count done and they're fine, I've had a sweat test to rule out CF, came back negative. I'm at a loss. Deep down I feel like something isn't right, this has been going on for a year now and is impacting my life and mental.

Update: I've recieved a Fibromyalgia and Raynaud's syndrome diagnosis
Original Post: Hello, I was wondering if anyone else in this sub has been diagnosed or believe they have the possibility of polymyositis, as I've only seen like 4 posts about it here and I'm interested to hear your experience if you want to share. Fibromyalgia may also be a possibility for me too.
Symptoms I have are:

• Sensitivity to touch (literally a poke, slap on the back, an arm on my shoulder hurt so bad)
  
• Tension and aching pain in neck, both shoulders while doing nothing or whenever I'm stressed or doing a physical activity like just walking
  
• Sensitivity to touch mostly occurs in both thighs, neck, both shoulders, both upper arms, both lower arms, both sides of hips, both sides of lower back
  
• Daily overall feeling of dullness /weighed down muscles all over
  
• Showering/washing hair can be painful because of lifting arms
  
• Walking for some time even if it's like 10 minutes results in neck tension pain
  
• Jaw clenches shut when not aware and even when sleeping
  
• Tender jaw pain, cheek bones, and sensitive to touch there
  
• When jaw is opened wide there's a small pop or crack sound?
  
• Left knee clicks when I walk sometimes (a year ago there was also intense pain because they would lock after sitting, but it seems to have disappear)
  
• Pins and needles that occur in feet and fingers after crossing legs, keeping arm in the same position, but it happens in less than 10 minutes
  
• Feet and fingers also turn blue in less than 10 minutes whenever pins and needles happen, however sometimes they get cold on their own
  
• Chronic fatigue
  
• Having to turn over in bed multiple times because of neck pain and it hurts laying down and lifting head
  
• Creptius (grinding sound of sand) in neck when turning head
  
• Shortness of breath after going up stairs
  
• Constipation and bloating
  

Everyday I feel like a 5/10 to 6/10 in pain. I don't know what it feels like to wake up with no pain for a day
I am diagnosed with ADHD, anxiety and depression and take Zoloft and Concerta. I read there's a link between ADHD and TMJ, but I also assume I might be having side effects from Zoloft which are jaw clenching and constipation. I also have hyperhidrosis which is excessive sweaty hands and feet, that also contributes to my cold hands and feet because sweat cools off your body, however I still have poor circulation it seems to my fingers and feet. I'm only 19 and have had these symptoms since 14 which seem to get worse. I don't wear thin strapped purses anymore because they're so painful, but it's funny because if it's a large strapped bag I can - my reasoning behind that is the surface area of a tiny strap maximizes the pressure so it hurts more, think of it like a high heel shoe stepping on your feet vs. a regular shoe. The high heels would hurt more because of maximized surface area to pressure. But even then I can't wear large strapped bags for too long before it starts to hurt.
I've gotten an xray done and the nerves are normal only "some inflammation" in muscles, but the doctor just brings up posture because of my age. I'm still going to try and pursue blood testing for CK levels and an MRI because those provide more details on your muscle tissues. It was also noted in a blood test I did my iron count is low, but they didn't say anything else.

On my first day, I wasn't going into it being very optimistic. I had read some posts on here from other people's experiences. I figured if I could see even a 1% improvement, it would be huge. So on day one, I started with 50mg and downloaded a journal app on my phone to keep track of how I was feeling. I didn't have many symptoms except for liquid shyte for a couple of weeks, and hyperhidrosis for which I got a beta-blocker and take 50mg a day to reduce hypertension. I upped the zoloft to 75mg a day after 7 days and then 100mg/day 7 days after that. I'm not sure if I should keep upping my dose. Its kind of hard being your own doctor and self-prescribing all these meds. I'm not sure how to know if I need to take 125 - 150 mg a day, I don't know if it will allow me to achieve anything more if I do. I do feel like I have made improvements in some areas of my life due to this SSRI. I have more energy to do things, and even socialize with people. I care more about my place being clean. I find myself cleaning a lot. I notice I smile and laugh a lot more now. I have more tolerance and patience with other people, I used to be very short fused and get agitated easily and didn't enjoy talking with many other people much. I still don't like most people, but I can tolerate them more now. I am able to be more pleasant and social. I still haven't changed my largely pessimistic view of the world, but maybe I consume too much political news. I do feel overall that my mental health has improved and I am glad I started taking this drug. I was worried about my ability to get an erection and ejaculate, but I've tested that throughout my progression and no problems. I can't say that I feel fantastic, but I have seen much improvement and I feel like I can make even more progress. I think my weight has stayed the same, maybe lost a little bit. I do practice intermittent fasting, but the serotonin rush in my stomach makes me hungry and very sleepy so I switched to taking it at night. So far, no negative side effects or interactions with the THC I consume. My sleep hasn't improved much, still getting 6 - 7 hours a night. SSRI was definitely needed, I think I had been living without it for too long. I still think there is something missing here though. There is still room to improve. I adopted a scared dog from a shelter, I've had it for a week. I started giving it zoloft too, hopefully it will come out of it's shell and want to be a dog again.

I'm sure the answer is no, but is there anything a person can do about this infernal racket? I have a really bad headache (just drastically reduced my Zoloft dosage and then switched to Prozac, hoping that's the cause), and a bunch of them, at least 50, probably more, were going up and down my street (Spring Garden, near 22nd) for like fifteen minutes straight. They eventually left but every few minutes a bunch come back and the noise is just irritating me so much. It goes on until well past 1 am usually. There's never, like, a full half-hour without some going by. It's hot in my apt so I have to have the window open (I have hyperhidrosis), but even without the window open, it's just. So. Loud. I am maybe more sensitive to loud noises than most people (trucks, loud music, babies crying make me want to throw something), but this is just neverending..I guess I'm just wanting to know if it is happening to anyone else this often, if anything can be done, and if not, can you at least reassure me I'm not the only one really pissed off? Thanks.

Honestly, I don’t know what to do. I appreciate this thread because of the real life experiences and the advice.
Some background on me: I am a 21 year old female. I suffer from excessive underarm sweating and face sweating. I have been dealing with the underarm sweating for about 4 years now. When I initially went to the doctor for the underarm sweating, they gave me prescription deodorant. I used that for a while and then stopped. Later on down the road, I’m working and I am dripping sweat from my armpits. I wore a red t-shirt at work so you could see my huge sweat stains. So embarrassing. I went to the doctor and got some Drysol, and got put on anxiety medicine. I deal with the hyperhydrosis and I also deal with social anxiety. The social anxiety makes me sweat, but the sweating gives me anxiety. It’s really hard to explain, but I hope there’s someone that understands where I’m coming from. I’ve gone to a few primary care doctors and no one is much help. I’ve been prescribed citalopram, Zoloft, and bupropion for my anxiety. I don’t care for the anxiety medicines a whole lot because they seem to totally take away my sex drive but I’ve still been on them for the past couple of years. Currently I am taking 20mg of Citalopram and bupropion with it, which was supposed to help cancel our the sexual side effects. I don’t think it helps a ton. The anxiety medicines don’t seem to help my sweating go away much. For hyperhidrosis I’ve been prescribed 10mg of Oxybutinin and I’m still taking that. I use the Drysol at night. Currently, none of it is doing a whole lot. I mean, of course the combination is doing something but I still am suffering. The Drysol doesn’t help my underarm sweating much anymore. The Oxybutynin does help me not sweat as much on my face though. To explain my social anxiety and Hyperhidrosis link, I’d give the example of work. I have the most social anxiety when it comes to working. Dealing with customers and coworkers gives me anxiety and it makes me sweat on my face and armpits more. I start to notice the sweating on my face and it makes me freak out more. It’s hard to deal with in everyday life and enjoy work. I feel like I won’t ever want to move up in my career because I’m not confident enough. To sum up what I’m trying to say : I’m struggling with a combination of social anxiety and Hyperhydrosis. I’ve deal with the underarm sweating for a while now, that’s a separate issue. I know that when I worry about it and think about it I sweat more. The social anxiety and facial sweating are definitely linked. I start sweating on my face when I have anxiety with dealing with customers at work. Nothing is really helping. I’m so embarrassed at work and unconfident. I think my brain is just wired this way now because of my constant anxious thinking the past few years. I think I should try Cognitive Behavioral Therapy with a mixture of medicine. I just can’t find the right medicine. As far as hyperhidrosis, I was thinking glyco? I need advice and stories and support and insight and any and everything you can give me please. I’m hopeless right now. Thanks guys.

34
Male
6'1"
230lbs
Caucasian
1 Year, sporadic
New Jersey, USA, N/A
Primary Hypothyroidism, Hypogonadism
Synthroid, Gabapentin, Zoloft, Clonazepam
N/A
I have been experiencing what I find to be bizarre episodes of Hyperhidrosis and elevated heart rate. Sometimes it's simply being in the hot weather for a minute or two, sometimes it's very mild exercise. I know this isn't a medical term or a quantifiable number, but it's bananas how much and how quickly I sweat sometimes, and it can be accompanied by an elevated heart rate that can last an hour or more (110-120 BPM while sitting down). I have been diagnosed about 18 months ago with primary hypothyroidism though I recently changed endocrinologists because I found my original doc to be unreliable, and have recently switched from levothyroxin to synthroid, and I was taking Clomid but discontinued recently (unclear what testosterone levels are now, haven't been tested in months).
I was inspired to post here because just yesterday I was vacuuming my apartment which is not very large with a self propelled vacuum cleaner and I started sweating like a lunatic and my heart was beating fairly fast. I sat down and continued sweating profusely for maybe 10 minutes? And using a heart monitor I saw that my heart rate stayed in the 110 area for at least an hour before its slowly returned to normal. To be clear, I can do a half an hour on an exercise bike and not have nearly the same issue with sweat and heart rate, so this is totally mystifying to me. It feels sometimes like I'm a sweat bomb that just needs the slightest poke to pop and suddenly boom, sweating like I just ran a marathon, absolutely drenched on my face like I just got out of a pool, within a couple of minutes.
Any help understanding what's going on here would be appreciated.

Age 27, Male, United Kingdom
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For exactly 4 years I have been back and forth with doctors, trying to understand what is wrong with me.
I first noticed the excess sweating, my feet would be in extreme discomfort and sweat in excess, but my whole body sweats a lot since then and can't handle heat well. My feet will always get (and I can't stress this enough) extremely uncomfortable and get a range of burning/numbness/tingling sensations. This leads to being in discomfort and changing socks throughout the day, and being miserable because of this.
Other symptoms would include several periods throughout each day of feeling spaced-out and faint, brain fog and confusion - maybe even depersonalisation - These symptoms scare me a lot, because I feel as though I have become brain dead and my brain is a potato, and sometimes I feel so intensely faint that I could fall down. There are periods where I am more alert though, when these symptoms aren't quite so intense.
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I have had every test under the sun carried out (either at suggestion from the doctor, or at my demand - thank the UK for national health care) to try solve this. Blood tests (vitamins/thyroid/vasculitis/lyme disease etc), nerves in my legs/feet, hyperhidrosis treatment, MRI brain/spine, anxiety treatment - currently I am taking 100mg Sertraline (Zoloft?).
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I have used drugs recreationally (generally MDMA), but I did try a 'lesser known' psychedelic called ' 4-HO-MET' around the similar time that these health problems arose. My new doctor told me that he believes that it may have damaged the pathways or neurons in the brain, which will be causing these problems. Damage that wouldn't be seen on an MRI.
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I stopped smoking 2 years ago, I have been going to the gym regularly for 2 years, I have been taking multivitamins and omegas on/off for the past year, and have been eating a plant-based diet since the new year. Currently I take 100mg Sertraline that I'm hoping may somehow help stabilise my brain neurons, or at the least make me feel a bit better. I am due to get some therapy (maybe CBT or something).
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How else may I go about healing? I just need to be better, It has tortured me for 4 years. I have learned to manage it better, but it pains me each day and has taken over my life and ruined my social life.
Thank you for reading and for any help.

I've been dealing with clammy hands, clammy feet, and general warmness almost constantly for the last 2 weeks.
I'm a super hypochondriac, and let everything that happens get to me. For example, last year my body was twitching for about a month then it stopped. My doc said it was just a physical representative of my anxiety.
Is it possible that this is too? I know hyperhidrosis is a thing, but they aren't so dripping like examples online. I also don't have like any other symptoms that would point to more serious stuff. I exercise regularly via running, drink tons of water, vitamins, etc.
Its the same loop. Things settle down at night. But when I wake up my feet get cold and clammy, my hands get clammy and my heart rate just blows me away. Feeling so nervous until I take my Zoloft.
Please help. 😷

I am bipolar 1, rapid cycling. I have been on Lamictal for about 10years, and it has deffinately brought things in check a little better. With the lamictal, i have tried seroquil, prozac, zoloft, welbutrin, and now Effexor. I also have narcolepsy and take the non stimulant wakefulness medicine Modafinil. I have been on the Effexor for over a year now, and Its the closest I have felt to being me since I first got medicated. However, I still can be very easily triggered into a self-harm ideating depression. I think I'm having the same amount of, if not more, suicidal thoughts than before. Further, the Effexor gives me incredibly believable suicidal nightmares every single night, as well as hyperhidrosis. I take hydroxyzine and prazosin to combat those side effects, but I don't think either one is helping at all. I'm really scared to go off of Effexor because I was seriously non functional before getting on it, but the side effects are getting to be more than I can bare. Any advice would be welcome. Thank you so much.

This was the first doctor I ever saw about my anxiety. She diagnosed me with social phobia and prescribed me Zoloft , which I had requested. Tried it for a bit but it didn't' work which she said was normal and that we can keep trying medications.
I was then given Paxil and Ativan PRN. The Paxil seemed to help me a bit. By the time my prescription was running out I was really liking Paxil and Ativan didn't really do anything. She kept me on Paxil and switched the Ativan with Xanax. Remember this bit.
They told me I could request a refill over the phone. After weeks of scary phone calls trying to figure out why my prescription was never available even though it should have been I finally gave up around November of last year.
About 2 weeks ago I finally got the small courage needed to go see my doctor again. She says we're going to try something new this time and send my pharmacy a new prescription. It was Ativan again. Same dosage. I called her office later that day to explain the situation and they told me they'd swap it out for something else. A couple days later they tell me to pick up a new prescription.
I look at it when I'm back home. It's Xanax. Same dose. I call again and explain that once again she gave me the same thing. It was then over the phone that her assistant told me "nothings working for you so she's recommending you to a therapist" I said "but these sedative's shes been pushing haven't done anything, what about the SSRI's the Paxil?" "The xanax is the strongest thing she can give you so she's recommending a therapist."
I hung up angrily and tried to not let my co-workers see me teary eyed. I don't want therapy. I'm sure I couldn't afford it. I don't want some med school drop-out trying to tell me that my facial twitches, hyperhidrosis, and uncontrollable shaking is "all in my head".