So I really had no intentions of taking progress pics because I'd gotten so used to avoiding makeup-free selfies at any cost (even if they were just for me to see). But I just couldn't believe this was actually my skin when I looked in the mirror today and felt like I just had to document it. I'm nearly 37 and I can't believe I let myself suffer for 24 years before embracing accutane.
Apologies for my goofy looking mouth in the first set (I was biting my tongue in concentration, haha).
The second set of photos were taken about six weeks ago, right before taking my first dose (at my dermatologist's urging). This was after most of my foundation had melted/flaked off my skin midway through the day (as it did most days), but overall, I had actually considered that a great skin day as I had no active cysts. Still, my skin was so congested, inflamed, and angry all the time, even when it was in "healing" mode. Basically, as long as I had no active, painful explosions, I considered myself blessed. I would say my acne was mild-moderate but maddeningly persistent, and it just always looked...unhealthy? There was nothing I'd tried up to this point that managed to yield anything but the most temporary of results (and trust, I have tried EVERYTHING under the sun).
I was determined to microdose from the beginning, and am planning on staying on it for as long as I can—ideally lowering to a maintenance dosage of 10-20mg a week. I've only taken a total of 40mg a week for the last six weeks (10mg on Tuesdays, Wednesdays, Fridays, and Saturdays). I take it with a big spoonful of peanut butter and a claritin. I also take NAC and Milk Thistle for extra liver support. Plenty of water, obviously. I've honestly had ZERO side effects that I'm aware of—not even bothersome dryness, really. Though I do keep myself properly slugged pretty much whenever I'm home. My topical routine is exceedingly simple and gentle.
Topical Routine:
PM—double cleanse with baby shampoo, apply about a quarter-sized pour of pure vegetable glycerine to very damp skin and let it air-dry, then slug with vaseline
AM—splash with cold water, mix a nickel-sized pour of vegetable glycerine in my wet hand with a small shake of l-ascorbic acid powder from The Ordinary, mix it well, apply it all over my still damp face, and let air dry before GENEROUS globs of SPF 50 everywhere that isn't covered with clothing.
No makeup but lip gloss and a bit of mascara occasionally (makes SPF re-application easier).
https://preview.redd.it/17g1kk89k91d1.png?width=1958&format=png&auto=webp&s=eced4b293b489ae678d9788ea21e7955681e2698
https://preview.redd.it/b3jeop5ak91d1.png?width=1368&format=png&auto=webp&s=0bbda767dc0a72843a0087557f8c1102bca21eee

I've seen discussions on why Dimitri is/isn't so plagued by hallucinations that he loses all reason in different routes but I've always been surprised that no one offers what seems to me to be the most obvious answer - Rhea is medicating him to keep him docile.
Why do I think Rhea is medicating Dimitri? Well it wouldn't be the first time she used medicine as a means to temper emotions. In WC on all routes iirc, she offers a quest in which she asks you to distribute special herbs to several students she deems as "troubled". I believe Ashe (who just lost his adoptive father) is among them - and given Lord Lonato's ties to revolutionaries it would be detrimental to her if Ashe became emotional enough to lash out against the Church.
So if Ashe, and I believe Marianne and Annette (?) are big enough security risks for Rhea if they are ill at ease, it's almost certain that Dimitri is too. If she is as observant as Jeralt says she is then she could easily have recognised Dimitri's darker side just as Felix did and began medicating him early on. Since it's revealed in his support line with Ingrid that he has little to no sense of taste, it wouldn't even be hard to do so without his knowledge.
When the war starts in AM, VW and SS, Rhea and Dimitri are separated. His rapid decline in all three routes would align with his removal of access from emotion-stabilising herbs without an appropriate reduction period after prolonged use. Before long follow auditory and visual hallucinations and violent impulses, the likes of which had never appeared so intensely during his time at the Academy but had appeared to some extent in his childhood, if Felix is to be believed.
In a CF route, however, he stays with Rhea during the war. If he is not still being medicated five years later, she would have at least been able to properly manage reducing dosages until he had basically been staved off of it since she never disappeared. It would explain why CF is the sole route in which he hasn't fallen to a level of mental instability in which he can no longer be reasoned away from his constant bloodlust.
So yeah. That's my head canon

Okay so to start my husband began having a histamine type reaction all over his body many months ago. We saw his PCP then a few specialists, one thought maybe he had developed an allergy to tattoo ink because it did seem to be worse under one specific tattoo, but that did not explain the full body hives so they let that go. (We did the whole change laundry soaps and hand and body soaps and check our house and remove all new things etc etc)
After a few months of back and forth appointments it kind of cleared up a bit. Not all the way but dramatically. At the time I did not put 2 and 2 together to realize that it was at the same time of the shortages. He got bumped from 10mg hydrocodone to 7.5 and his dr did not match his dosage. Essentially his dosage was cut in half.
Pharmacy gets 10s back and they give him back his proper dosage and the full body hives are back but in over drive. He is blistered. And we noticed that after a few hours of taking one it eases some so its like peak he's fully covered in hives and blisters and as the medicine fades so does the reaction.
Now I have done a ton of reading overnight and found that it is probably a psuedoallergy. A mast histamine reaction. Apparently the majority of allergic reactions to opioids are more this then the anaphylaxis kind. It could also be a reaction to the acetaminophen in the same way. We are going to investigate that further.
From what I've been able to find if it is an allergy to the hydrocodone he is limited to taking hydromorphon (i probably spelled that incorrectly but Im sure you get the gist), tramadal, or fentanyl (the last obviously wouldnt be something they would prescribe). Tramadol does not work for him we have tried that route before. Idk about the other.
It could also be the manufacturer. He never had any problems when our pharmacy carried camber (which has discontinued making hydrocodone) this all actually started when they swapped to mallinckrodt (which is garbage anyway) but it is the only manufacturer anyone in this area has. So trying to swap manufacturers probably wont be something we can do either. (Thank you DEA for continuing to push shortages and give us crap medication pushed out by very few manufacturers, camber used food product, the yellow color being from corn starch, as their fillers the one time i found info on mallinckrodt it was mostly chemical because why put natural things in a human body...)
If he is lucky and it is the acetaminophen I know there is an ER hydrocodone without acetaminophen but I do not know, and cannot seem to find, if there is an IR without acetaminophen.
Do any of you know if there is and the info on it? Or one containing ibuprofen instead of acetaminophen?
These are all shots in the dark right now obviously as we havent nailed down if its the manufacturer, the medication as a whole, or the acetaminophen, I just want to have some info in the back of my mind. I have found going in completely ignorant of anything relevant to the situation is, for us, when we end up being ignored, things being missed, or being given only one treatment option because it is easiest for the provider, and ends up being the worst choice. The trauma I have experienced due to drs just flares if I have no information.
Thank you in advance to anyone that has any info or advice.

I am making this post based on my experience after seeing previous complaints in other places about Jatenzo and having to take it twice a day like it's some chore. Do you eat twice a day? Then, what's the big deal? I do take it with fat to ensure good absorption.
Anyway, it has been nothing short of miraculous. Much of the TRT pages are geared toward weightlifters or FTM. I'm just a regular-born male who needs to take testosterone for health reasons. After testicular cancer 11 years ago at age 29, my one functioning testicle had to be removed (the other one was destroyed by an incompetent doctor who didn't descend it properly as a kid). So, I don't make any except for the tiny bit made elsewhere. I tried gels. Axiron worked great at first....and mimicked natural cycles, which is important to me. Then, it stopped absorbing. And other gel forms didn't work. Then, I went on shots every few weeks. Wild swings. And even with the high levels at the start, I didn't "feel" like it was working.
Enter Jatenzo. I waited a good year for this drug when I heard about it. And for all the people that don't know, it's a new pill form that DOES NOT HARM THE LIVER. My liver is doing fine after several years now. I was the first one my internal medicine doctor prescribed this medicine for, and I ended up leaving the urologist since he wouldn't prescribe it. The worst part has been getting insurance to cover it. It has been a battle every time I got new insurance, but I think my lack of testicles makes them more likely to cover it than just demand I do the shots.
I feel so much better on this than the shots! My energy is higher, I feel mentally better, and every morning, I have a rager right before waking up. It's like I'm a teen again. One weird difference between this and the injectable was that I had a ridiculous number of nocturnal emissions with the shots. With this, just the morning wood. I will take that. I think it's impacting my libido in a way that presents differently and in a superior way to the injections. And my wife is glad to not have to give me injections.
Honestly, I am surprised at how well my numbers have improved on Jatenzo. At first, it seemed to be around 600, but I recently had 700. Keep in mind, I don't make testosterone on my own, so I am almost on the max dose: 2 158 mg pills twice a day. There is only one dosage higher than this. I take it with peanut butter and fish oil capsules. I am sure my numbers would be much lower otherwise. Note: You are supposed to take labs 6 hours after the morning dose, which is different than other forms. So, these numbers are well past the peak number.
Anyway, I just wanted to share my positive experience as a person taking this for my essential health reasons, not just for slightly low levels but absurdly low if I didn't take it. I am worried about the future, as the original manufacturer of this folded and sold the product to another company. It's expensive, so I use the discount card, which means I really only pay $10. I hope they never discontinue this discount, but they likely will once it gets closer to going generic unless they also fold or pull it from the market like what happened to Axiron.
If I ever can't take this, I will try micro-dosing injectables, but I will be angry about having to do that with a pill form. It will feel like a punishment. Maybe it would more naturally mimic natural cycles than the longer injection doses. But that's a what-if in the future. For now, I am grateful to have Jatenzo and insurance that finally accepts it.

Before considering buying steroids, it's essential to understand the potential risks, legal implications, and health considerations associated with their use. Here are some important factors to consider:

1. **Legal Status**: In many countries, steroids are controlled substances and can only be obtained with a prescription for medical purposes. Purchasing steroids without a prescription or from illegal sources can result in legal consequences.
   
2. **Health Risks**: Steroids can have serious side effects, including liver damage, cardiovascular issues, hormonal imbalances, infertility, and psychiatric effects such as mood swings and aggression. Long-term use can lead to dependency and addiction.
   
3. **Purpose**: Understand why you want to use steroids. Are you looking to enhance athletic performance, improve muscle mass, or treat a medical condition under the supervision of a healthcare professional? Using steroids for non-medical purposes is risky and can have serious consequences.
   
4. **Quality and Source**: If you're obtaining steroids, ensure that they are from a reputable source and are of pharmaceutical grade. Underground labs and black market products may be contaminated or of poor quality, posing additional health risks.
   
5. **Dosage and Administration**: Proper dosage and administration are crucial for minimizing health risks. If you're unsure about how to use steroids safely, consult with a qualified healthcare professional or endocrinologist.
   
6. **Potential Interactions**: Steroids can interact with other medications and supplements, potentially causing adverse effects. Make sure to disclose all medications and supplements you are taking to your healthcare provider before starting steroid use.
   
7. **Monitoring and Follow-up**: Regular monitoring by a healthcare provider is essential while using steroids to monitor for potential side effects and adjust treatment as necessary.
   
8. **Alternative Options**: Consider alternative strategies for achieving your goals, such as proper nutrition, training, and supplementation with legal and safer substances.
   
9. **Personal Health**: Consider your own health status and any pre-existing medical conditions before using steroids. Certain medical conditions may be exacerbated by steroid use.
   
10. **Long-Term Implications**: Think about the long-term implications of steroid use on your health, including potential effects on fertility, hormonal balance, and overall well-being.
    

Bit of a story - cathartic to write it down so please humour me. Background: 50 yo. Started with pelvic issues when around 16 years - had loads of urodynamics - cystoscope, flow tests but none conclusive so sent on my way! Just ended up living with it - back then late 80s not much in the way of resources to look things up! Never mind support groups like this :) Now over 30 years later I reflect back on how much it impacted me mentally - I used to be quite extrovert and at sixteen just coming out of myself - wanting to find a gf, etc. But the pelvic issues totally knocked my self confidence, self esteem - always felt like I was wetting myself - sweating in class ruminating on whether or not to put my hand up to leave for yet another wee, thinking everyone was watching me. I could never pee at wall urinal if anyone else in the bathrooms. Exams were a nightmare! I kind of just accepted it in the end and lived with it - that need to pee more than most people - maybe I just had a small/overactive bladder and things did settle enough that I could get on with life. At 21 I did finally get a gf but in hindsight it ended up being quite a toxic relationship- i think I was always too desperate to keep the peace and let her walk all over me due to my lack of self. My bladder issues would flare every couple of years- usually when I’ve been stressed - invariably the GPs would give me antibiotics just in case of a uti (despite no tests ever being conclusive) which did help- now knowing more about antibiotics it was probs more down to their anti-inflammatory properties or maybe a placebo effect. Here I am two divorces down the line but thankfully in a really equal supportive relationship the last 9 years. Self confidence has grown over the many years - I think as we get older we give less of a shit on how other people perceive us , or at least I do! You’d think I’d knocked all the pelvic issues on the head but I think it’s been a a ticking time bomb. I have always struggled with anxiety not helped with stressful divorces - battles over children/finances is no fun - so when the pandemic hit I have to admit i was super covid anxious and was hyper careful. Mad really in hindsight! But no one really knew fa in 2020. Then in 2021 I suffered an injury to my testicles - my stupid dog jumped up at me. After three weeks I was still having throbbing pains so the GP suspected epididymitis and some kind of infection and ‘just in case’ (as there was a waiting list for scans) prescribed me Cipro. OMG - hindsight would be a wonderful thing -suffice to say I had a bad reaction, couldn’t walk properly due to pain for several months , had bad GI issues, neurological flashing pains and other weird shit. Also a lot of anger that GPs dish them out like smarties. This did not help my anxiety- but weirdly my pelvic issues were calm given the stress. Until May 22 when my partner got Covid . So stressed about catching it seemed to tip me over the edge and my bladder flared big time. Constant tingling in meatus, urgency, pain in pelvis. Urologist did US, flow and blood tests but only thing wrong was poor flow which I’ve always had. So referred me to an IC specialist. He was useless , barely listened , didn’t do any tests and just prescribed me solafenacin and hydroxyzine . The hydroxyzine did help my sleep and I kind of got back a new level normal . I did see a PPT but didn’t really help. I did ask my gp for amitriptyline in Dec 22 which helped even more and most of my aches and pains subsided. NOW: a few weeks ago all my symptoms came roaring back. Lot of discomfort , barely able to sleep. Anxious about cancer. Yesterday New Urologist has reassured me that if I’d had cancer this last two years I’d know about it by now so still thinks it’s pelvic related. He’s booked me in for MRI to check prostrate. My psa is normal and it was a normal size when checked with US two years ago so it’s more just to rule it out. Also prescribed Toviaz (Fesoterodine) to see if that helps. To add. I’ve worked in IT all my career - desk based, sitting down. Relatively fit - used to cycle most weekends, play racquet ball, , run, hill walking. Cipro did stop of a lot of exercises but as I’ve recovered have started climbing at the local climbing gym. Climbing does weirdly help - when I’m doing it my discomfort does ease - maybe all the stretching moves. Has anyone any other advice they can offer up? Just sick of the constant tinkling in meatus and aches below tummy button . Thanks for bearing with me!

Good Day!
About 12 hours ago, I was bitten by my pup on the finger, at 12 AM, it was small like a knife or a paper cut. It bled but I cleaned it right away with water and alcohol.
My pup was born inside of our house, is almost 5 months old, has not gone outside of our house and came in contact with other dogs or animals. He was recently dewormed 2 weeks ago, (and only got dewormed again and his first shot of anti-rabies just earlier, about 3 hours ago). He’s very normal and healthy, spoiled even as he stays indoors.
However when he bit me he still didn’t have any anti-rabies shot. I was quickly brought to the hospital at around 12:30 AM or so, it’s a hospital nearby.
It was a category 3 animal bite because it bled yes and the nurses followed the protocol treatment, making it day 0.
I took these shots in 4 of my limbs;

1. Anti-Rabies shot
2. Erig Vaccine with proper dosage based on my weight.
3. Two Tetanus Shots

I will be coming back once a week for for more anti-rabies shots then will come back in 6 months for another shot (I forgot what type it was, was it a booster?)
I got back home around 2 AM.
All that I ask now is if you believe that I will not likely get rabies now that I was treated as fast a possible? I’m just very anxious and I am terrified of the symptoms.
I actually almost contracted rabies again before, it was a decade ago, I was around 9 or 10 years old. I was scratched by an actual stray kitten I picked up, it clunged on my wrists too hard and slid its claws down. The wound was bleeding so much I still remembered it vividly.
I was brought to the nearest Animal Bite center I had to take 10 shots, once a week, I of course don’t remember what kinds of shots they were. I didn’t take rabies before seriously as a kid since I was innocent and unaware of how lethal it was, all I knew is that I had to visit the doctor once a week for those shots. I couldn’t believe I went through a much terrible wound before as a kid, unlike the one I got earlier, a small bite from a pup.
Am I completely safe now?

Around Late March 2024 I started taking prozac for anxiety I was having. For the first 4 weeks I felt kinda of dull emotionally so I went down to 10mgs as I was taking 20mgs and from then on I was feeling better, but out of nowhere around 5 days ago (can’t even remember properly the days have just been a blur) I started having insane instrusive thoughts about suicide. I felt like I enjoyed absolutely nothing as well, and I started having panic attacks and extreme anxiety about it even having to go to the ER because of one. (On the night I went to the ER I ended up taking my full dose that night because I thought it would help I know that doesn’t really help but I was so confused and tried anything) after that I then went back down to 10mgs again and it’s gotten even worse I feel nothing, now im only taking 5mgs as of last night I haven’t even left my bed today. I feel like that one night where I took 20mgs and then immediately went back to 10 really did some damage I just have no clue what im doing I’ve been so scatterbrained and im very young I just don’t know what to do do I stay on 5mgs and wait for the side effects to go away? Or go back up. I’m scared of my brain dealing with all of this dosage switching. It genuinely feels like it’s never going yo go away I want to feel something again. Hopefully this post is readable im a little frantic.
If any clarification is needed please comment and ask I’ll reply

i got diagnosed almost 2 years ago and was prescribed 50mg elvanse (vyvanse in the USA). everything was great it was literally the best thing ever I was talkative, happy, had no anxiety at all and felt very confident all the time. I was full of energy and motivation. I was able to hold proper conversations for long periods of time and this made me happy cuz I usually struggle with this. I took a break from my meds for 2-3 months because it caused me to experience slight weight loss as I wasn’t eating properly.
I started taking them again with the exact same dosage but now it completely takes away my personality. I am still able to focus but I’m literally so fucking boring and quiet with them. It also makes feel very anxious and not confident. I literally hate taking it now yes I’m able to focus at work and school but I’ve become such an emotionless boring person because of this. Like I get so serious lmao.
side notes: I am anaemic and I don’t take my iron tablets so maybe that’s why ? I’m not completely sure
I also drink a lot of redbull but I know you shouldn’t while taking elvanse so I’ve stopped but I’m still experiencing the “boring personality” effects.

Title: Understanding Fentanyl: Uses, Risks, and Controversies
Introduction: Fentanyl, a potent synthetic opioid, has gained significant attention in recent years due to its role in the opioid epidemic. This article aims to provide a comprehensive overview of fentanyl, including its medical uses, associated risks, and the controversies surrounding its widespread misuse.
Medical Uses: Originally developed for managing severe pain, especially in cancer patients, fentanyl is an analgesic that is 50 to 100 times more potent than morphine. It is commonly used in medical settings for pain management during surgeries, chronic pain conditions, and palliative care.
Risk Factors: While fentanyl is effective in controlling pain when administered under medical supervision, its misuse poses serious health risks. The drug's high potency increases the likelihood of overdose, leading to respiratory depression and, in extreme cases, death. Illicitly manufactured fentanyl, often mixed with other substances, has been a major contributor to the rising number of opioid-related deaths.
Controversies and Illicit Use: The illicit use of fentanyl has sparked controversy and public health concerns. The drug is often clandestinely produced and added to other drugs, such as heroin or cocaine, without the user's knowledge. This has resulted in a surge in overdoses, as individuals may unintentionally consume lethal doses of the opioid.
Law Enforcement and Regulation: Governments and law enforcement agencies worldwide are grappling with the challenges posed by the illicit production and distribution of fentanyl. Efforts to regulate its manufacturing and distribution are ongoing, with stricter controls in place to prevent diversion into illegal channels.
Treatment and Harm Reduction: Addressing the fentanyl crisis requires a multi-faceted approach, including expanded access to addiction treatment, harm reduction strategies, and public awareness campaigns. Naloxone, an opioid receptor antagonist, has proven effective in reversing opioid overdoses and is increasingly available to first responders and the general public.
Conclusion: Fentanyl, with its remarkable pain-relieving properties, has become a double-edged sword in the realm of healthcare. While it serves a crucial role in medical settings, its misuse poses severe risks to public health. Efforts to combat the opioid epidemic must focus on education, regulation, and treatment to strike a balance between managing pain effectively and preventing the tragic consequences of its illicit use.
Narcan, also known by its generic name naloxone, is a medication used to rapidly reverse opioid overdose. It works by binding to the same receptors in the brain that opioids target, effectively reversing the life-threatening effects of opioid toxicity. Narcan is commonly administered in emergency situations where an individual is experiencing respiratory depression or unconsciousness due to opioid overdose.
Emergency responders, healthcare professionals, and even some non-professionals, such as family members of individuals at risk of opioid overdose, may carry naloxone. The medication is available in various forms, including nasal sprays and injectable formulations, making it accessible for different situations.
The prompt administration of Narcan can restore normal breathing and consciousness, providing crucial time for the affected person to receive further medical attention. It is an essential tool in harm reduction strategies aimed at preventing opioid-related deaths and is a key component of public health initiatives addressing the opioid epidemic.
Suboxone is a prescription medication used in the treatment of opioid dependence and addiction. It is a combination of two active ingredients: buprenorphine and naloxone.

1. Buprenorphine: This is a partial opioid agonist, meaning it binds to the same receptors in the brain that opioids bind to but with less intensity. It helps to reduce cravings and withdrawal symptoms, allowing individuals in recovery to better manage their addiction.
   
2. Naloxone: Naloxone is an opioid receptor antagonist, which means it blocks the effects of opioids. When taken as directed, naloxone remains largely inactive. However, if someone were to misuse Suboxone by injecting it, the naloxone component can counteract the opioid effects, reducing the risk of misuse.
   

Suboxone is often prescribed as part of medication-assisted treatment (MAT), a comprehensive approach to opioid addiction that includes counseling, therapy, and support services. It can be used in the detoxification phase as well as for long-term maintenance therapy. The goal of Suboxone treatment is to help individuals gradually reduce their dependence on opioids, manage cravings, and improve their overall quality of life during recovery.
It's important to note that Suboxone should only be used under the supervision of a qualified healthcare professional, as improper use or abrupt discontinuation can lead to withdrawal symptoms or other complications.
Precipitated withdrawal refers to the accelerated onset of withdrawal symptoms, often more severe than typical, when an opioid antagonist is introduced to the body. This occurs because the antagonist displaces the opioid from receptors, leading to a sudden and intense withdrawal reaction.
For example, if someone is currently dependent on opioids and receives a medication like naloxone or naltrexone, which are opioid antagonists, it can rapidly trigger withdrawal symptoms. This is a safety mechanism, as these medications are often used to reverse opioid overdose or as part of addiction treatment.
The term is commonly associated with medication-assisted treatment for opioid use disorder, where medications like buprenorphine (a partial opioid agonist) are used. If buprenorphine is administered before other full opioids have cleared from the system, it can displace those opioids from receptors, leading to precipitated withdrawal. This is why healthcare providers carefully time the initiation of medications like buprenorphine to avoid this intensified withdrawal reaction.
Understanding the potential for precipitated withdrawal is crucial in the context of addiction treatment to ensure safe and effective transitions between medications and to minimize discomfort for individuals in recovery.
Using Suboxone involves adherence to a specific treatment plan under the guidance of a qualified healthcare professional. Here are some key aspects related to the use of Suboxone:

1. Prescription and Medical Supervision: Suboxone is a prescription medication, and its use should be initiated and supervised by a qualified healthcare provider, typically in the context of medication-assisted treatment (MAT) for opioid use disorder.
   
2. Dosage: The healthcare provider will determine the appropriate dosage based on the individual's specific needs and response to the medication. It's essential to follow the prescribed dosage and not adjust it without consulting the healthcare provider.
   
3. Administration: Suboxone is often administered sublingually, meaning it is placed under the tongue and allowed to dissolve. This method allows for the absorption of the medication into the bloodstream.
   
4. Timing: The timing of Suboxone administration is crucial. It is often started when the individual is in a mild to moderate state of withdrawal to reduce the risk of precipitated withdrawal. The healthcare provider will provide guidance on the appropriate timing.
   
5. Regular Monitoring: During Suboxone treatment, individuals are regularly monitored by healthcare professionals to assess progress, manage side effects, and adjust the treatment plan as needed.
   
6. Counseling and Support: Suboxone is typically part of a comprehensive treatment plan that includes counseling, therapy, and support services. This holistic approach addresses both the physical and psychological aspects of opioid addiction.
   
7. Gradual Tapering: Depending on the treatment plan, there may be a gradual tapering of Suboxone dosage as the individual progresses in their recovery. Tapering is done under medical supervision to minimize withdrawal symptoms.
   
8. Avoiding Other Opioids: It's crucial to avoid the use of other opioids while taking Suboxone. Combining opioids can lead to dangerous interactions and diminish the effectiveness of the treatment.
   
9. Side Effects and Reporting: Like any medication, Suboxone may have side effects. Common side effects include headache, nausea, and constipation. Any unusual or severe side effects should be promptly reported to the healthcare provider.
   
10. Pregnancy Considerations: If an individual is pregnant or planning to become pregnant, it's important to discuss this with the healthcare provider, as the use of Suboxone during pregnancy requires careful consideration.
    

Always follow the guidance of your healthcare provider and inform them of any concerns or changes in your condition during Suboxone treatment. Successful recovery often involves a combination of medication, counseling, and support tailored to individual needs.
Suboxone, when used as prescribed under the supervision of a healthcare professional as part of medication-assisted treatment (MAT) for opioid use disorder, has a lower potential for abuse and addiction compared to full opioid agonists. This is because Suboxone contains buprenorphine, a partial opioid agonist, which has a ceiling effect on its opioid effects.
Buprenorphine's partial agonist properties mean that it activates opioid receptors in the brain to a lesser extent than full agonists like heroin or oxycodone. As a result, the euphoria and respiratory depression associated with opioid abuse are less pronounced with buprenorphine.
However, it's essential to emphasize that any medication, including Suboxone, should be taken exactly as prescribed by a healthcare professional. Misuse, such as taking larger doses or combining Suboxone with other substances, can increase the risk of dependence or addiction.
Abruptly stopping Suboxone can lead to withdrawal symptoms, emphasizing the importance of a gradual tapering plan under medical supervision when discontinuing the medication. It's crucial for individuals using Suboxone to work closely with their healthcare provider to ensure proper management of their opioid use disorder and to address any concerns or side effects during the course of treatment.
Withdrawal symptoms from Suboxone, or buprenorphine (the active ingredient in Suboxone), can occur when someone who has been using the medication for an extended period stops taking it abruptly. It's important to note that withdrawal symptoms can vary in intensity and duration based on factors such as the individual's overall health, the duration of Suboxone use, and the dosage.
Common withdrawal symptoms from Suboxone may include:

1. Nausea and vomiting
2. Diarrhea
3. Muscle aches and pains
4. Sweating
5. Insomnia or sleep disturbances
6. Anxiety
7. Irritability
8. Runny nose and teary eyes
9. Goosebumps (piloerection)
10. Dilated pupils

It's important to distinguish between withdrawal symptoms and precipitated withdrawal. Precipitated withdrawal can occur if someone takes Suboxone too soon after using a full opioid agonist, leading to a more rapid and intense onset of withdrawal symptoms.
Withdrawal from Suboxone is generally considered less severe than withdrawal from full opioid agonists, and the symptoms tend to peak within the first 72 hours after discontinuation. However, the duration and severity can vary from person to person.
If an individual is considering stopping Suboxone or adjusting their dosage, it's crucial to do so under the guidance of a healthcare professional. Tapering the medication gradually, rather than stopping abruptly, can help minimize withdrawal symptoms and increase the chances of a successful transition to recovery. Seeking support from healthcare providers, counselors, and support groups is essential during this process.
Kratom is a tropical tree native to Southeast Asia, specifically in countries like Thailand, Malaysia, Indonesia, Papua New Guinea, and Myanmar. The leaves of the Kratom tree have been traditionally used for various purposes, including as a stimulant, a pain reliever, and to manage opioid withdrawal symptoms.
The active compounds in Kratom, called alkaloids, interact with opioid receptors in the brain, producing effects that can vary depending on the strain and dosage. These effects can include:

1. Stimulation: At lower doses, Kratom may act as a stimulant, promoting increased energy, alertness, and sociability.
   
2. Sedation: At higher doses, Kratom may have sedative effects, leading to relaxation and pain relief.
   
3. Pain Relief: Kratom has been used traditionally for its analgesic properties, and some people use it as a natural remedy for pain.
   
4. Mood Enhancement: Some users report improved mood and reduced anxiety after consuming Kratom.
   

However, it's important to note that Kratom is not regulated by the U.S. Food and Drug Administration (FDA), and its safety and effectiveness for various uses have not been clinically proven. There are potential risks associated with Kratom use, including dependence, addiction, and adverse effects such as nausea, constipation, and increased heart rate.
Due to these concerns, Kratom has been a subject of regulatory scrutiny in various countries, with some regions imposing restrictions or outright bans on its sale and use. It is essential for individuals to exercise caution, seek reliable information, and consult with healthcare professionals before considering the use of Kratom, especially for medicinal purposes or to manage opioid withdrawal.
Methadone is a synthetic opioid medication used primarily in the treatment of opioid dependence, particularly in the context of medication-assisted treatment (MAT). It is a long-acting opioid agonist, meaning it activates the same opioid receptors in the brain that other opioids, like heroin or morphine, do.
Key points about Methadone include:

1. Opioid Dependence Treatment: Methadone is often used as a maintenance medication to help individuals reduce or quit the use of illicit opioids. It helps by reducing cravings and withdrawal symptoms.
   
2. Long-Lasting Effect: One significant advantage of methadone is its long duration of action. A single daily dose can help stabilize individuals, preventing the highs and lows associated with short-acting opioids.
   
3. Supervised Administration: In some cases, methadone is provided through supervised administration in specialized clinics to ensure proper use and minimize the risk of diversion.
   
4. Tolerance and Dependence: Like other opioids, individuals using methadone can develop tolerance and dependence. Therefore, the dosage needs to be carefully managed, and discontinuation should be done gradually under medical supervision.
   
5. Reduction of Illicit Drug Use: When used as part of a comprehensive treatment plan, methadone has been shown to reduce illicit opioid use, lower the risk of overdose, and improve overall health outcomes.
   
6. Potential Side Effects: Methadone can have side effects, including constipation, sweating, drowsiness, and changes in libido. It's important for individuals to report any adverse effects to their healthcare provider.
   
7. Regulated Use: The use of methadone is tightly regulated, and it is typically dispensed through specialized clinics or healthcare providers who are authorized to prescribe it for opioid use disorder treatment.
   

Methadone treatment is part of a broader approach that often includes counseling, therapy, and support services. It has been a valuable tool in harm reduction strategies aimed at addressing the opioid epidemic and helping individuals achieve and maintain recovery.
Narcotics Anonymous (NA) is a 12-step program that provides support for individuals recovering from addiction, particularly those struggling with substance abuse issues. It is important to note that NA, like other 12-step programs, does not have an official stance or opinion on specific medical treatments, including medication-assisted treatment (MAT) for withdrawal.
The approach to medication assistance in withdrawal can vary among individuals within the NA community. Some may find success and support in MAT, while others may choose alternative methods or prefer an abstinence-based approach. NA encourages individuals to share their experiences, strength, and hope, but it does not dictate specific treatment choices.
The primary focus of NA is on mutual support, fellowship, and following the 12-step principles, which include admitting powerlessness over addiction, seeking spiritual awakening, and helping others in recovery. Members of NA are encouraged to respect each other's choices and paths to recovery.
It's essential for individuals seeking support for addiction to find a treatment plan that aligns with their needs and values. Consulting with healthcare professionals, attending support groups, and considering various treatment options can be part of a comprehensive approach to recovery.
SMART Recovery (Self-Management and Recovery Training) is a science-based, secular alternative to traditional 12-step programs like Narcotics Anonymous. SMART Recovery emphasizes self-empowerment and utilizes evidence-based techniques to support individuals in overcoming addiction.
Regarding Medication-Assisted Treatment (MAT), SMART Recovery takes a neutral stance. The program acknowledges that MAT, when prescribed and monitored by healthcare professionals, can be a valid and effective part of a comprehensive approach to addiction treatment. SMART Recovery recognizes that different individuals may have unique needs, and treatment plans should be tailored to the individual's circumstances.
SMART Recovery's focus is on teaching self-reliance, coping skills, and strategies for managing urges and behaviors associated with addiction. The program encourages participants to make informed decisions about their recovery, including the consideration of medications that may be prescribed by healthcare providers.
Ultimately, SMART Recovery emphasizes a holistic and individualized approach to recovery, allowing participants to choose the methods and tools that best suit their needs and align with their values. This includes being open to the potential benefits of MAT for some individuals as part of their overall recovery plan.
Several treatment modalities are available for individuals struggling with opioid use disorder. The most effective approach often involves a combination of different strategies. Here are some key treatment modalities for opioid addiction:

1. Medication-Assisted Treatment (MAT): MAT involves the use of medications, such as methadone, buprenorphine (Suboxone), and naltrexone, to help manage cravings, reduce withdrawal symptoms, and support recovery. These medications are often used in combination with counseling and therapy.
   
2. Counseling and Behavioral Therapies: Various forms of counseling and behavioral therapies are crucial components of opioid addiction treatment. Cognitive-behavioral therapy (CBT), contingency management, motivational enhancement therapy, and dialectical behavior therapy (DBT) are among the approaches used to address the psychological aspects of addiction and help individuals develop coping skills.
   
3. Support Groups and 12-Step Programs: Participating in support groups like Narcotics Anonymous (NA) or 12-step programs can provide valuable peer support, encouragement, and a sense of community for individuals in recovery.
   
4. Detoxification Programs: Medically supervised detoxification programs help individuals safely manage the acute withdrawal symptoms associated with stopping opioid use. These programs often serve as the initial phase of treatment.
   
5. Residential or Inpatient Treatment: Inpatient treatment programs provide a structured and supportive environment for individuals to focus on recovery. These programs may include a combination of medical supervision, counseling, and therapeutic activities.
   
6. Outpatient Treatment: Outpatient programs allow individuals to receive treatment while living at home. This flexibility can be beneficial for those with work or family commitments. Outpatient treatment often includes counseling, therapy, and medication management.
   
7. Holistic and Alternative Therapies: Some individuals find benefit from holistic approaches, such as acupuncture, yoga, meditation, or mindfulness practices. These can complement traditional treatment modalities and contribute to overall well-being.
   
8. Peer Recovery Support Services: Peer recovery support services involve individuals with lived experience in recovery providing support, guidance, and encouragement to others going through similar challenges.
   

The most effective treatment plans are often individualized, taking into account the specific needs, preferences, and circumstances of each person. Collaborating with healthcare professionals to develop a comprehensive and tailored approach can significantly enhance the chances of successful recovery from opioid addiction.
The withdrawal timeline for fentanyl, a potent synthetic opioid, can vary among individuals based on factors such as the duration and intensity of use, individual metabolism, and overall health. Fentanyl withdrawal symptoms typically start shortly after the last dose and follow a general timeline:

1. Early Symptoms (Within a few hours): Early withdrawal symptoms may include anxiety, restlessness, sweating, and increased heart rate. Individuals may also experience muscle aches and insomnia.
   
2. Peak Intensity (24-72 hours): Withdrawal symptoms usually peak within the first 24 to 72 hours after discontinuing fentanyl. During this time, individuals may experience more intense symptoms such as nausea, vomiting, diarrhea, abdominal cramps, dilated pupils, and flu-like symptoms.
   
3. Subsiding Symptoms (5-7 days): The most acute withdrawal symptoms generally begin to subside within about five to seven days. However, some symptoms, such as insomnia, anxiety, and mood swings, may persist for a more extended period.
   
4. Post-Acute Withdrawal Syndrome (PAWS): Some individuals may experience a more prolonged period of withdrawal symptoms known as post-acute withdrawal syndrome (PAWS). This can include lingering psychological symptoms such as anxiety, depression, irritability, and difficulty concentrating. PAWS can persist for weeks or even months.
   

It's crucial to note that fentanyl withdrawal can be challenging, and seeking professional help is recommended to manage symptoms safely and effectively. Medical supervision can provide support through the detoxification process, and healthcare professionals may use medications to alleviate specific withdrawal symptoms and improve the overall comfort of the individual.
The withdrawal process is highly individual, and some individuals may find additional support through counseling, therapy, and participation in support groups to address the psychological aspects of recovery. Always consult with healthcare professionals for guidance on the safest and most effective approach to fentanyl withdrawal.
Xylazine is a veterinary sedative and analgesic medication. It belongs to the class of drugs known as alpha-2 adrenergic agonists. While it is primarily intended for veterinary use, xylazine has been misused in some cases for recreational purposes, particularly in combination with other substances.
In veterinary medicine, xylazine is commonly used as a sedative and muscle relaxant for various procedures, including surgery and diagnostic imaging. It is often administered to calm and immobilize animals.
However, the use of xylazine outside of veterinary settings, especially when combined with other drugs, can pose serious health risks. Misuse of xylazine has been associated with adverse effects, including respiratory depression, cardiovascular issues, and central nervous system depression.
It's important to emphasize that the use of xylazine for recreational purposes is highly dangerous and illegal. The drug is not intended for human consumption, and its effects can be unpredictable and potentially life-threatening.
If you have concerns about substance use or encounter situations involving illicit drugs, it is crucial to seek help from healthcare professionals, addiction specialists, or local support services. Misuse of veterinary drugs or any substances not prescribed for human use can have severe consequences and should be avoided.
PAWS stands for Post-Acute Withdrawal Syndrome. It refers to a set of prolonged withdrawal symptoms that some individuals may experience after the acute phase of withdrawal from substances like opioids, benzodiazepines, or alcohol. PAWS is not limited to a specific substance and can occur with various drugs.
These symptoms are generally more subtle than the acute withdrawal symptoms but can persist for weeks, months, or, in some cases, years after discontinuing substance use. PAWS can vary widely among individuals and may include symptoms such as:

1. Mood swings
2. Anxiety
3. Irritability
4. Insomnia
5. Fatigue
6. Difficulty concentrating
7. Memory problems
8. Reduced impulse control
9. Cravings for the substance

PAWS can be challenging for individuals in recovery, as these lingering symptoms may contribute to relapse if not effectively managed. Supportive interventions, such as counseling, therapy, and participation in support groups, can be beneficial for individuals experiencing PAWS. Healthy lifestyle choices, including regular exercise, proper nutrition, and adequate sleep, may also contribute to the overall well-being of those in recovery.
It's important to note that PAWS is not experienced by everyone in recovery, and its severity and duration can vary. Seeking guidance from healthcare professionals or addiction specialists can assist individuals in managing PAWS and maintaining long-term recovery.
Quitting substance use "cold turkey" involves stopping the use of a substance abruptly without tapering or gradually reducing the dosage. It's important to note that quitting cold turkey can be challenging, and the level of difficulty varies depending on the substance, the duration and intensity of use, and individual factors.
If you're considering quitting a substance cold turkey, here are some general recommendations:

1. Seek Professional Guidance: Before making the decision to quit cold turkey, it's advisable to consult with a healthcare professional or addiction specialist. They can provide guidance based on your specific situation, assess potential risks, and offer support.
   
2. Create a Support System: Inform friends, family, or a support network about your decision to quit. Having a support system in place can provide encouragement, understanding, and assistance during challenging times.
   
3. Understand Withdrawal Symptoms: Be aware of potential withdrawal symptoms associated with quitting the substance cold turkey. Withdrawal symptoms can vary depending on the substance but may include anxiety, irritability, insomnia, and other physical or psychological effects.
   
4. Stay Hydrated and Nourished: Maintaining proper hydration and nutrition is crucial during the quitting process. Stay hydrated by drinking water and consuming a balanced diet to support your overall well-being.
   
5. Exercise: Engage in regular physical activity. Exercise can help alleviate stress, improve mood, and contribute to your overall physical and mental health.
   
6. Consider Professional Treatment: Depending on the substance and the severity of dependence, professional treatment options, such as inpatient or outpatient programs, may be beneficial. Medical supervision can assist in managing withdrawal symptoms and ensuring safety.
   
7. Therapy and Counseling: Consider participating in therapy or counseling to address the underlying factors contributing to substance use and to develop coping strategies for a successful recovery.
   
8. Plan for Triggers: Identify situations, environments, or emotions that may trigger the urge to use the substance. Develop a plan to cope with these triggers without resorting to substance use.
   

It's essential to approach quitting any substance with a comprehensive strategy, and individual circumstances vary. Seeking professional advice ensures that you make informed decisions about the best approach for your specific situation. If you are experiencing severe withdrawal symptoms or have concerns about quitting cold turkey, it is crucial to consult with a healthcare professional for guidance and support.
Tapering refers to the gradual reduction of the dosage of a substance, typically a medication or a drug, over a specific period. Tapering is commonly used in the context of addiction treatment, where it involves slowly decreasing the amount of a substance to manage withdrawal symptoms and minimize the risks associated with abrupt discontinuation.
Key points about tapering include:

1. Medication-Assisted Treatment (MAT): Tapering is often part of medication-assisted treatment for substance use disorders. For example, individuals dependent on opioids might undergo a gradual tapering of medications like methadone or buprenorphine.
   
2. Reducing Dependence: Tapering is employed to reduce physical dependence on a substance by allowing the body to adjust to lower levels gradually. This helps minimize the severity of withdrawal symptoms.
   
3. Individualized Approach: Tapering plans are typically individualized based on factors such as the substance used, the duration and intensity of use, and the individual's overall health. Healthcare professionals design tapering schedules to meet the specific needs of each person.
   
4. Supervised Tapering: Tapering is ideally done under the supervision of a healthcare professional to ensure safety and effectiveness. This is particularly important in cases where abrupt discontinuation could lead to severe withdrawal symptoms or complications.
   
5. Psychological Support: Tapering is not only about physical adjustments but also addresses psychological aspects of dependence. It provides individuals with an opportunity to develop coping skills and strategies for managing life without reliance on the substance.
   
6. Preventing Relapse: Gradual tapering can help reduce the risk of relapse by easing the transition to complete abstinence. It gives individuals the time and support needed to adjust to life without the substance.
   

Tapering is a careful and structured process that should be guided by healthcare professionals. Abruptly stopping certain substances can lead to severe withdrawal symptoms and potential health risks. Seeking professional advice and support is crucial for a safe and successful tapering process, whether it's part of addiction treatment or the discontinuation of a prescribed medication.
Engaging in activities during withdrawal can help distract from symptoms, provide a sense of accomplishment, and contribute to overall well-being. Here are some ideas for keeping busy during withdrawal:

1. Reading: Escape into a good book or explore topics of interest to keep your mind occupied.
   
2. Movies or TV Shows: Watch movies or binge-watch a TV series to pass the time. Choose lighthearted or inspirational content.
   
3. Exercise: Engage in gentle exercises like walking, yoga, or stretching. Exercise can help improve mood and alleviate some withdrawal symptoms.
   
4. Creative Hobbies: Explore creative outlets such as drawing, painting, writing, or playing a musical instrument.
   
5. Mindfulness and Meditation: Practice mindfulness or meditation techniques to calm the mind and reduce stress.
   
6. Gardening: Spend time outdoors, tending to a garden or plants. Nature can have a positive impact on mood.
   
7. Puzzle Games: Solve puzzles, play Sudoku, or engage in other mentally stimulating games.
   
8. Listening to Music or Podcasts: Create playlists of your favorite music or listen to podcasts on topics of interest.
   
9. Cooking or Baking: Experiment with new recipes and treat yourself to nourishing meals.
   
10. Journaling: Write down your thoughts and feelings. Keeping a journal can be therapeutic during withdrawal.
    
11. Educational Courses: Take online courses or watch educational videos on platforms like Coursera or Khan Academy.
    
12. Board Games or Card Games: Play board games or cards with friends or family for some social interaction.
    
13. Self-Care Activities: Take relaxing baths, practice skincare routines, or indulge in other self-care activities to nurture your well-being.
    
14. Volunteering: If possible, consider volunteering for a cause you're passionate about. Helping others can be rewarding.
    
15. Stay Connected: Reach out to friends and family for support. Having a support system is crucial during withdrawal.
    

It's important to choose activities that align with your interests and energy levels. Remember that withdrawal is a challenging time, and it's okay to prioritize self-care. If symptoms become severe or unmanageable, seeking professional help is recommended.

I love seeing the posts where people finally find their cocktail, or can say they’ve been stable for x number of years. However, I find myself questioning what that truly means. My journey began long ago misdiagnosed as so many of you can relate to, but my bp2 diagnosis came in 2020. It made so much sense and I was so grateful to finally have something I could learn about and work on, but here we are 4 years later and I don’t feel any closer to stability than I did back then. I’ve been on a dozen or more medications, most with negative side effects, I’ve had genetic testing done to help narrow it down but it still seems that no matter what I try, I still don’t feel…good. I’m currently on Lurasidone and just upped the dosage last week, it makes things…tolerable at best but not even that great some days. I have no motivation or energy, and I’m still experiencing the extreme cycles of hypomania and depression. I guess I’m just curious to see what being properly medicated means for me, am I supposed to still be experiencing such highs and lows? I know it won’t ever go away, but what does stable mean for someone with bipolar? I went hypomanic earlier this year than my normal pattern and I’ve been on the decline over the past week and I’m just feeling so hopeless and discouraged that this will ever be better. I know it’s the depression, but damn it’s hard to feel positive about something that’s so chaotic, unstable, and completely out of my control. I also know the medication journey can be a tough one. I’d love to hear some success stories to garner some hope that better days are ahead.

Introduction
An excessive rise in blood sugar or glucose is known as "Diabetes Mellitus". The primary form of sugar in blood is blood glucose, which also serves as the body's primary energy source. In addition to being produced in the muscles and liver, glucose is obtained via diet. All of the body's cells receive glucose from the blood to utilize as fuel.
The hormone known as insulin, which transports glucose to every cell in the body, is released into the circulation by the pancreas, an organ situated between the stomach and the spine. When the pancreas produces insufficient insulin or insulin that is not functioning properly, glucose remains in the bloodstream instead of entering cells. Diabetes can be brought on by excessive blood glucose levels. Diabetes can affect people of any age or gender. Diabetes occurs in three basic types: Type 1, Type 2, and Gestational Diabetes.
Type 1 diabetes:
Although it can occur in adults as well, type 1 diabetes, often known as juvenile diabetes, primarily affects young people. Due to an immune system attack and subsequent destruction of the insulin-producing cells (pancreatic beta cells), type 1 diabetes results in insufficient or nonexistent insulin production. You won't get diabetes if you eat too much sugar, despite popular belief. The immune system of a person with Type 1 diabetes attacks the beta cells in their body, which produce insulin, which is how the disease began. Monogenic diabetes is the term for a subset of rare types of diabetes caused by mutations or alterations in a single gene. The two primary types of monogenic diabetes are Maturity-Onset Diabetes of the Young (MODY) and Neonatal Diabetes Mellitus (NDM).
Before the age of six months, diabetes is more likely to be non-diabetic diabetes mellitus (NDM) than autoimmune Type 1 Diabetes Mellitus (T1DM). MODY refers to a class of hereditary autosomal-dominant conditions characterized by early-onset, usually moderate hyperglycemia (high blood sugar). Rather than insulin resistance, it is the consequence of beta-cell malfunction. MODY is associated with mutations in a minimum of eight genes. There is an older group with the slower onset disease in addition to the typical young individuals with acute onset T1DM. They may appear to have Type 2 Diabetes Mellitus (T2DM) in middle age, but tests for the anti-glutamic acid decarboxylase (GAD) antibody show indications of autoimmunity. Eventually, they develop an insulin-dependent lifestyle. This condition is known as Adult Latent Autoimmune Diabetes (LADA).
Complications of diabetes
Complications from diabetes have been shown to significantly raise health care expenditures for both treating and managing the disease as well as increasing morbidity and mortality. Diabetic patients who have out-of-range diabetes treatment and higher long-term blood glucose levels are more likely to experience microvascular and macrovascular problems.
Blood glucose levels that are too high over time can lead to a number of problems, including:

• Diseases of the eyes caused by alterations in fluid levels, tissue edema, and injury to the blood vessels in the eyes
• Foot issues brought on by nerve damage and decreased blood flow to your foot
• Gum disease and other dental issues, as harmful bacteria are encouraged to proliferate in your mouth by a high blood sugar level in your saliva. Food particles and bacteria interact to create plaque, a soft, sticky film. Eating foods high in sugar or carbohydrate can also cause plaque. Certain kinds of plaque lead to foul breath and gum disease. Cavities and tooth decay are caused by other types.
• Damage to your blood vessels and the nerves that regulate your heart and blood vessels can result in heart disease and stroke.
• Renal disease brought on by harm to the kidneys' blood arteries. Diabetes frequently results in elevated blood pressure. That could also be bad for your kidneys.
• Damage to the nerves and the tiny blood arteries that supply your nerves with oxygen and nutrients might result in nerve issues (diabetic neuropathy).
• Nerve injury and decreased blood supply to the genitalia and bladder can lead to sexual and urinary issues.
• Disorders of the skin, some of which are brought on by modifications to the small blood vessels and poor circulation. It is also more common for people with diabetes to get infections, particularly skin infections.

Additionally, acute hyperglycemia emergencies can be brought on by high blood glucose levels. These emergencies consist of:

• The most common cause of ketoacidosis, a potentially fatal condition marked by hyperglycemia and elevated blood acid (ketone) levels, is type 1 diabetes.
• Hyperosmolarity is a condition that causes the body to lose water from its organs. It is marked by prolonged hyperglycemia without ketoacidosis and severe dehydration.

Management of diabetes
Type 1 diabetes is a complicated illness that needs to be managed on a daily basis with effort and preparation. Here are some tips to help you effectively manage your Type 1 diabetes:
Check your blood sugar frequently: Using a continuous glucose monitor (CGM) or a glucometer to check your blood sugar is essential for managing diabetes and avoiding complications. If nothing else, make an effort to monitor your blood sugar levels before bed and after meals. Treating high blood sugar as soon as feasible is crucial.
Regularly take your insulin and other medications: Pay attention to the directions provided by your healthcare practitioner when taking your insulin and any additional drugs, if any.
See your endocrinologist frequently: To ensure that your Type 1 diabetes treatment plan is effective, it's critical to see your endocrinologist frequently. Don't be hesitant to pose targeted queries to them.
See your eye doctor and all of your other providers on a regular basis. Complications from type 1 diabetes can affect many parts of your body, but particularly your eyes. It's crucial to visit your ophthalmologist (eye doctor) at least once a year so they can examine your eyes.
Plan ahead for a sick day: Consult your endocrinologist about self-care and managing your diabetes during illness. Diabetes-related ketoacidosis (DKA) can be brought on by illness, so it's critical to be prepared by knowing what to do if you become ill in advance.
Stay educated: Never be reluctant to inquire about Type 1 diabetes with your healthcare physician. Your chances of leading a healthy life and avoiding problems from Type 1 diabetes increase with your level of knowledge about the disease and how to manage it.
Find a community: Making online or in-person connections with other Type 1 diabetics can make you feel less isolated while managing your condition.
Ensure your emotional well-being: Compared to people without diabetes, people with diabetes have a two to three times higher risk of depression and a 20% higher chance of receiving an anxiety diagnosis. Having a chronic illness that needs ongoing care can be very demanding. In the event that you exhibit symptoms of depression, it is imperative that you consult a mental health expert.
Conclusion
Four daily actions can help blood glucose levels remain within the desired range:
I. Stick to a balanced diet.

1. Engage in physical activity.

III. Regulate the dosage of insulin.
IV. Monitor diabetes.
At first, these tasks could seem overwhelming. Make minor adjustments until completing these actions becomes a regular part of your day.
To prevent hypoglycemia, learn to balance your insulin dosage with each meal and physical activity. Establish a goal range for your blood sugar and raise your HbA1c (keep it between 6% and 7%). Take part in running events and diabetic camps to network with other Type 1 diabetics and gain insight from their experiences. Stay positive, do yoga, and meditate. People can resume their normal lives and no longer have to fear diabetic consequences once they have learnt how to manage their diabetes.

INTRODUCTION
Diabetes mellitus (DM) is a heterogeneous metabolic disorder characterized by a common feature of increased levels of blood glucose (or blood sugar), which over time may lead to serious damage to the nerves, blood vessels, heart, and various organ systems of the body.
The most characterized feature of diabetes is insulin resistance by the Beta cells of the pancreas.
GESTATIONAL DIABETES

1. One of the types of Diabetes Mellitus is Gestational Diabetes i.e., Diabetes during pregnancy.
   
2. About 4% of pregnant women develop DM due to metabolic changes during pregnancy. Although they revert to normal glycemia (normal blood glucose) after delivery, these women are prone to develop DM later in their lives.
   

OTHER TYPES OF DIABETES MELLITUS

1. Type 1 D. M:

Type 1 diabetes is a condition that results from an abnormal immune response where certain cells called “T-cells” which are a part of the Beta cells of the pancreas are destroyed. Type 1 diabetes is based on the “gene-environment interaction” model i.e., individuals who are susceptible to certain environmental triggers develop resistance to the activity of Beta cells which in turn results in low or no production of insulin. Type 1 diabetes is strongly influenced by genetic predisposition but it does not follow any particular pattern of inheritance.

1. Type 2 D. M:

Type 2 diabetes mellitus is a heterogeneous condition that is characterized by varying degrees of insulin resistance (where insulin rejects synthesis of carbohydrates) and beta-cell dysfunction, Beta cells are those cells that are part of the pancreas that produce insulin. Type 2 diabetes is commonly associated with obesity.
In type 2 diabetes, there are mainly two problems. The pancreas can not produce enough insulin (the hormone that regulates the movement of sugar into the cells). The cells do not respond properly to insulin and synthesize less sugar. Type 2 diabetes used to be known as adult-onset diabetes, but both type 1 and type 2 diabetes can begin during childhood and adulthood. Type 2 is more common in the older generation but due to the increase in the number of children with obesity, more cases of type 2 diabetes are seen in the younger generation.

1. Other specific types:

Only 10% are affected by this type of D. M and this includes Genetic defects, endocrinopathies, etc.
TREATMENT

1. Treatment for Gestational diabetes depends on the signs and symptoms of the individual, the age, and the severity of the condition.
   
2. To maintain blood glucose levels, medication that lowers blood sugar levels may be given in the form of tablets.
   
3. A proper diet has to be followed.
   
4. Exercise as prescribed by the doctor.
   
5. For higher blood sugar levels insulin is required to be administered.
   

SIDE EFFECTS OF INSULIN
Increased insulin leads to increased glucose in a baby’s system which may keep the lungs from growing fully. This can cause breathing problems in babies. This is mostly seen in babies born before 37 weeks of pregnancy.
If insulin is given in higher concentration then it may lead to hypoglycemia (decreased blood sugar level) which may lead to loss of consciousness, coma, severe and irreversible brain injuries, or death.
CONCLUSION
While the right doses of insulin have no ill effects on the human body, higher doses can lead to severe conditions that may even result in death. Therefore all insulin dosages have to be prescribed by a qualified physician.

In the realm of health and wellness, managing blood sugar levels is a cornerstone for overall well-being. Enter Gluco6, a cutting-edge solution engineered to revolutionize how we regulate glucose levels in the body. In this article, we delve into the essence of Gluco6, exploring its composition, functionality, usage, benefits, drawbacks, and overall impact on health.
What is Gluco6?
Gluco6 is a dietary supplement meticulously crafted to support healthy blood sugar levels. It combines a synergistic blend of natural ingredients renowned for their efficacy in glucose management. Designed with a holistic approach, Gluco6 aims to empower individuals with a proactive means of maintaining optimal blood sugar levels and promoting vitality and wellness.
Ready to take control of your Gluco6 sugar levels? Start here!
How Does Gluco6 Work?
At the heart of Gluco6 lies its potent formula, which harnesses the power of critical ingredients to regulate blood sugar levels effectively. Let's break down some of its primary components:
· Sukre: Derived from the Stevia plant, Sukre offers a natural sweetness without the glycemic impact of sugar, making it an ideal alternative for individuals looking to manage their blood sugar.
· TeaCrine: Known for its stimulating properties, TeaCrine enhances mental clarity and focus without causing spikes in blood sugar levels, providing sustained energy throughout the day.
· Gymnema: This herb has a long history in traditional medicine for its ability to support healthy blood sugar levels by promoting insulin production and reducing sugar cravings.
· Chromium: Chromium plays a pivotal role in carbohydrate metabolism, facilitating glucose transport into cells and thus helping regulate blood sugar levels.
· Cinnamon: Beyond its delightful aroma and flavor, cinnamon contains compounds that improve insulin sensitivity and aid in managing blood sugar levels.
· Green Tea: Rich in antioxidants, green tea supports overall health and assists in regulating blood sugar levels by improving insulin sensitivity.
How to Use Gluco6?
Gluco6 comes in convenient capsules, making it easy to incorporate into your daily routine. Simply take one capsule every morning according to the recommended dosage instructions provided on the packaging or as advised by a healthcare professional. For optimal results, taking Gluco6 consistently as part of a balanced diet and healthy lifestyle is advisable.
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Benefits of Gluco6
· Stabilized Blood Sugar Levels: Gluco6 leverages the synergistic effects of its natural ingredients to help maintain steady blood sugar levels throughout the day.
· Reduced Sugar Cravings: The inclusion of Gymnema in Gluco6 helps curb sugar cravings, promoting healthier dietary choices.
· Enhanced Energy and Focus: With TeaCrine and green tea, Gluco6 provides sustained energy and mental clarity without the rollercoaster of blood sugar spikes and crashes.
· Supports Overall Wellness: Beyond blood sugar management, the ingredients in Gluco6 offer myriad health benefits, ranging from antioxidant support to improved metabolic function.
Drawbacks of Gluco6
While Gluco6 presents a promising solution for blood sugar management, it's essential to acknowledge potential drawbacks, including:
· Individual variability: As with any supplement, the effectiveness of Gluco6 may vary among individuals based on factors such as diet, lifestyle, and underlying health conditions.
· Not a substitute for medical treatment: While Gluco6 can complement a healthy lifestyle and blood sugar management plan, it is not intended to replace medical treatment or medication for diabetes or other health conditions.
Conclusion: Unlocking the Potential of Gluco6
In conclusion, Gluco6 represents a promising advancement in blood sugar management. By harnessing the power of natural ingredients backed by scientific research, Gluco6 offers a holistic approach to supporting healthy blood sugar levels and overall well-being. However, it's crucial to consult with a healthcare professional before starting any new supplement regimen, especially if you have underlying health conditions or are taking medications. With proper use and adherence to a healthy lifestyle, Gluco6 can make a meaningful difference in those seeking to optimize their blood sugar levels and enhance their quality of life.
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https://www.espacobaiao.com/group/grupo-template-2-espaco/discussion/09e70fd4-2920-4125-bb32-fc7b0f51b2a2
https://www.beyondyogabysaillo.com/group/my-site-2-gruppe/discussion/b1cf7ec2-e467-40f9-b391-415b7c2eef3f
https://fms.microsoftcrmportals.com/forums/general-discussion/a81b0fa0-1414-ef11-9899-00224858ab07
https://ecosoft.microsoftcrmportals.com/en-US/forums/support-forum/de5e41cb-1414-ef11-a81c-000d3a2b9657
https://indspire.microsoftcrmportals.com/en-US/forums/support-forum/86029bdc-1414-ef11-989a-000d3a84ad0c
https://gtcs.microsoftcrmportals.com/forums/general-discussion/5c96b90f-f9ef-ee11-a81c-00224899c820
https://mbolatam.microsoftcrmportals.com/forums/support-forum/d760a103-1514-ef11-9899-002248ded6c3
https://sholinkportal.microsoftcrmportals.com/forums/support-forum/e41ce730-1514-ef11-989a-6045bdb94b21
https://thecontingent.microsoftcrmportals.com/forums/support-forum/c29d454c-1514-ef11-9899-6045bd030f63
https://forum.freeflarum.com/d/63304-gluco6-reviews-scam-warning-alert-what-to-know-before-using
https://diendannhansu.com/threads/gluco6-reviews-fake-or-legit-know-all-the-facts-before-buy.435134/
https://blog.rackons.in/gluco6-reviews-fake-or-legit-know-all-the-facts-before-buy

Contacted Eli Lily today because I wasn’t sure that my 2.5 pen injected properly, and after assurance that it did seem to have worked, I asked about the fact that I was not getting glycemic control with 2.5. Rep indicated that 2.5 was a starter dose, and not indicated for glycemic control. This was my 3rd dose of 2.5, and tonight even doubling up on my insulin dosage with my meal, I got blood sugar of 187. So, I know I am likely to have to increase dosage each month; however, Lily rep indicated the shortages would likely continue throughout the rest of this year, and my pharmacy, Caremark, put an advisory on the app indicating most pharmacies have limited to no supplies of GLP-1 antagonist drugs, and to anticipate making alternate treatment plans to manage diabetes during the shortage. Since I had better glycemic control on Byetta with a A1C of 5.8. I think I may go back to Byetta until this shortage resolves. I know this shortage really is bad for folks who have been on Mounjaro with such great results, but I thought folks would want to know about this info that I got today, so they can make appropriate alternative plans in case the run into no availability. I’m limited to using Caremark or CVS on my insurance, so that’s why I’ll probably have to go back on Byetta until this shortage is resolved. So, bummed, but it is what it is.

In the competitive world of fitness and bodybuilding, finding the right supplement to enhance performance and achieve goals can be challenging. D-Bal Max has garnered significant attention as a powerful supplement designed to boost muscle growth, increase strength, and improve overall performance. This comprehensive review will delve into the ingredients, side effects, benefits, and results of D-Bal Max in 2024 to help you make an informed decision.
D-Bal Max Reviews that happens? These folks love doing that so much that they will put their head in the sand

What is D-Bal Max?

D-Bal Max is a natural dietary supplement formulated to mimic the effects of the anabolic steroid Dianabol, but without the harmful side effects. It aims to promote muscle growth, enhance strength, and optimize overall performance by combining potent, natural ingredients that work synergistically to deliver impressive results.

Key Ingredients of D-Bal Max

Understanding the ingredients is crucial to evaluating the effectiveness of any supplement. Here is an overview of the key components in D-Bal Max:

1. Pro BCAA Complex: Branched-Chain Amino Acids (BCAAs) are essential for muscle growth and repair. They help increase protein synthesis, reduce muscle soreness, and prevent muscle breakdown during intense workouts.
2. 20-Hydroxyecdysterone: This plant extract is known for its strong anabolic properties. It enhances protein synthesis and nitrogen retention, leading to significant muscle gains and increased strength.
3. Whey Protein Complex: Whey protein is a staple in the fitness community as it quickly delivers amino acids to the muscles. It supports muscle growth, recovery, and overall performance.

Benefits of D-Bal Max

D-Bal Max offers a range of benefits for fitness enthusiasts and bodybuilders:

1. Increased Muscle Growth: The combination of BCAAs and 20-Hydroxyecdysterone promotes significant muscle growth, leading to a defined and muscular physique.
2. Improved Strength: Users report substantial improvements in their lifting ability and overall strength, enabling more intense and productive workouts.
3. Faster Recovery: The Whey Protein Complex and BCAAs support faster muscle recovery, reducing downtime between workouts and maintaining training consistency.
4. Natural and Safe: Unlike anabolic steroids, D-Bal Max is formulated with natural ingredients, minimizing the risk of unwanted side effects.

Potential Side Effects

While D-Bal Max is generally safe for most users, it is important to be aware of potential side effects:

1. Digestive Issues: Some users may experience mild digestive discomfort, such as bloating or gas, due to the whey protein content.
2. Allergic Reactions: Individuals allergic to any of the ingredients should avoid the supplement to prevent allergic reactions.
3. Hormonal Imbalances: Though rare, excessive use of supplements like D-Bal Max can potentially lead to hormonal imbalances. It is crucial to follow the recommended dosage and consult a healthcare professional if concerns arise.

User Results and Experiences

The effectiveness of D-Bal Max is supported by numerous positive reviews and user experiences. Many report significant muscle gains, increased strength, and faster recovery times within the first few weeks of use. Consistency, dedication to the training program, and proper nutrition play a crucial role in achieving the best results.

How to Use D-Bal Max

For optimal results, it is recommended to take three D-Bal Max capsules daily with water, preferably 30-45 minutes before your workout. This ensures that the ingredients are well-absorbed and can enhance performance during your training session.
D-Bal Max Reviews that happens? These folks love doing that so much that they will put their head in the sand

Conclusion

D-Bal Max stands out as a promising supplement for those looking to enhance muscle growth, improve strength, and optimize training performance. With its natural ingredients and positive user feedback, it offers a safer alternative to anabolic steroids. However, as with any supplement, it is important to use it responsibly and consult a healthcare professional if there are underlying health conditions.

(I also posted this on Hypothyroidism but figured it might help someone here as well - I have Hashimotos)
I switched to a dedicated team of thyroid specialists in March (2024). I haven't felt this great in years. No fatigue, no brain fog, little stress, I sleep great, no more depression, body pains are gone, and more. I'm 54 and have struggled with thyroid issues since my 20's or younger. For years the doctors told me it is all in my head - the single thyroid test they would do always came back normal. I found a specialist in my early 40's and felt great with the proper meds...then I moved to a different city a few years later and have struggled since.
I am now with Paloma Health (available in the U.S., countrywide). I was hesitant to go with them, because they do not take my insurance. Turns out it isn't that expensive (just a bit more than without insurance). They ran a full panel of tests (4 in total - never had this done before!). I met virtually with a doctor who focuses on thyroid. She changed the type of medication I was taking (which included T3, and it was pushing that T3 number too high). First 6 weeks of the new medication was too low a dose (though she said I should expect that to happen - she didn't want to push me into a hypo state). I took another panel of tests after that first 6 weeks, which clearly showed I have Hashimotos. She upped the dosage, and like a miracle, within a couple weeks I felt amazing!!
I had lost hope that I could ever feel this good again. I highly recommend Paloma Health! (I'm not affiliated in any way).

(I also posted this on Hypothyroidism but figured it might help someone here as well - I have Hashimotos)
I switched to a dedicated team of thyroid specialists in March (2024). I haven't felt this great in years. No fatigue, no brain fog, little stress, I sleep great, no more depression, body pains are gone, and more. I'm 54 and have struggled with thyroid issues since my 20's or younger. For years the doctors told me it is all in my head - the single thyroid test they would do always came back normal. I found a specialist in my early 40's and felt great with the proper meds...then I moved to a different city a few years later and have struggled since.
I am now with Paloma Health (available in the U.S., countrywide). I was hesitant to go with them, because they do not take my insurance. Turns out it isn't that expensive (just a bit more than without insurance). They ran a full panel of tests (4 in total - never had this done before!). I met virtually with a doctor who focuses on thyroid. She changed the type of medication I was taking (which included T3, and it was pushing that T3 number too high). First 6 weeks of the new medication was too low a dose (though she said I should expect that to happen - she didn't want to push me into a hypo state). I took another panel of tests after that first 6 weeks, which clearly showed I have Hashimotos. She upped the dosage, and like a miracle, within a couple weeks I felt amazing!!
I had lost hope that I could ever feel this good again. I highly recommend Paloma Health! (I'm not affiliated in any way).

I switched to a dedicated team of thyroid specialists in March (2024). I haven't felt this great in years. No fatigue, no brain fog, little stress, I sleep great, no more depression, body pains are gone, and more. I'm 54 and have struggled with thyroid issues since my 20's or younger. For years the doctors told me it is all in my head - the single thyroid test they would do always came back normal. I found a specialist in my early 40's and felt great with the proper meds...then I moved to a different city a few years later and have struggled since.
I am now with Paloma Health (available in the U.S., countrywide). I was hesitant to go with them, because they do not take my insurance. Turns out it isn't that expensive (just a bit more than without insurance). They ran a full panel of tests (4 in total - never had this done before!). I met virtually with a doctor who focuses on thyroid. She changed the type of medication I was taking (which included T3, and it was pushing that T3 number too high). First 6 weeks of the new medication was too low a dose (though she said I should expect that to happen - she didn't want to push me into a hypo state). I took another panel of tests after that first 6 weeks, which clearly showed I have Hashimotos. She upped the dosage, and like a miracle, within a couple weeks I felt amazing!!
I had lost hope that I could ever feel this good again. I highly recommend Paloma Health! (I'm not affiliated in any way).

So i went 150 XL for a month, after a month I upped to 300. Since the second week of 300 I feel irritable, I can't concentrate at all, my short- and long term memory is not working properly. My inner tension is really high.
I'm not sure if I should stick through it and it will even out? All in all i'm on wellbutrin for a month and a week. Orrr should i reduce the dosage to 150 again?
Thanks in advance! :)

I've read boron is more efficient if you cycle 9mg 2 weeks on 1 week off. Can anyone share their experience?