Amitriptyline and prozac

33, Male, 5’8, 133lbs Location: US
Medication: Zyrtec
Non smoker, non drinker, do not use drugs
Hello all, I was diagnosed with GERD, esoughigitis and functional dyspepsia in 2020 after extensive testing. I’ll pre-face this by saying I’ve had GERD dysphagia and constant trapped gas since 2005. It started when I was addicted to opiates as a teenager (I have been clean since 2012). The GERD was well managed up until 2020 with either Zantac 150mg or Omeprozole 20mg.
However in 2020 something happened. I developed all these other symptoms and stopped being able to tolerate PPIs/h2 blockers. The stabbing pain started in 2020. I’ve had 3 endoscopies since and they all show I have had mild esophagitis since 2020. It’s not going away because I’m unable to tolerate PPIs and h2 blockers as well as antacids because they my symptoms worse (fees like food sits in my stomach, bloating, belching whenever I take them).
Waking up in the morning when my stomach is empty I have zero pain. My pain gets worse as the day goes on and I eat more. Liquids give me no symptoms and I can go almost all day just drinking protein shakes and almost feel no pain or symptoms. As soon as I start eating solids it’s over. I also have dysphagia. The pain starts anywhere from 30 min-2 hours after eating I’ll get a burning searing pain in my solar plexus area 10/10 pain. It feels like someone’s jamming a scalding hot fire poker into my abdomen. It lasts for 5-10 seconds at a time and usually comes with belching. It comes every 5/10 mins and will last until my GI tract is completely empty (usually next morning), it gets worse the more I eat.
On my doctor’s advice and care I’ve tried every diet, I’ve tried amitriptyline, buspar, lexapro, Prozac, noritriptyline, lyrica, gabbipentin none have helped me. Ive tried stomach breathing and therapy neither have helped.
As far as conclusive tests, my PH study shows I have GERD but not frequent enough for surgery. My barium food study shows food delayed emptying from my esoughgas into my LES. All other tests normal.
My doctor tells me there’s nothing left she can do for me. She offered me a feeding tube since I’ve went from 175lbs to 135 in a year. I don’t really know what else to do at this point. I’m malnourished, in chronic pain, and feel like I’m going to live the rest of my life in this pain.
It feels like what I would imagine gastroparesis or SIBO would feel like, however both my tests for those were negative. I can’t help but feel there is something that is being missed or overlooked. Could anyone please give me any advice or insight as to what could be causing these issues? Any tests I should look into, any different meds I should try, etc.. thanks for taking your time reading this.

Hello all, I was diagnosed with GERD and FD in 2020 after extensive testing. I’ve always had GERD and trapped gas since 2005 it started when I was addicted to opiates as a teenager (have been clean since 2012). The the stabbing pain started in 2020. I have had mild esophagitis since 2020 as well because PPIs and antacids make my symptoms worse (fees like food sits in my stomach, bloating, belching whenever I take them).
My pain gets worse as the day goes on and I eat more. Anywhere from 30 min-2 hours after eating I’ll get burning searing pain in my solar plexus area 10/10 pain. It feels like someone’s jamming a scalding hot fire poker into my abdomen. It lasts for 5-10 seconds at a time and usually comes with belching. It will last until my GI tract is completely empty (usually next morning).
I’ve tried every diet, I’ve tried amitriptyline, buspar, lexapro, Prozac, noritriptyline, lyrica, gabbipentin none have helped me. My PH study shows GERD but not enough for surgery. My barium food study shows food delayed emptying from my esoughgas into my LES.
My doctor tells me there’s nothing left she can do for me. Liquids give me no symptoms and I can go almost all day just drinking protein shakes and almost feel no pain or symptoms. As soon as I start eating solids it’s over. I also have dysphagia. I don’t really know what else to do at this point. I’m malnourished, in chronic pain, and feel like I’m going to live the rest of my life in this pain.
It feels like what I would imagine gastroparesis or SIBO would feel like, however both my tests for those were negative. Anyone have similar symptoms? What has worked best for you?

50(F), 5'6", 157 lbs, currently taking:

• Visanne (dienogest) 2mg every 2nd day (prescribed for endometriosis)
• Prozac 10 mg daily (prescribed for anxiety/IBS-C)
• Amitriptyline 25 mg every second day (prescribed for migraine prevention)

I would like to go off all my medications to see (1) if I am peri/full menopause and (2) if my chronic and painful constipation will go away.
If I stop taking all my meds, what side effects could there be? I will talk to my family physician about this as well but looking for some pre-emptive advice or opinions as well.
Thanks!

Hi all, I thought I would perhaps ask for some outside perspective around some ongoing issues with my mental health.
24 / M / 173cm / 80kg / Ongoing
I see a consultant psychiatrist who specialises in addiction, childhood trauma and ADHD, all of which are included in my diagnoses. The list includes Poly-Substance Misuse Disorder, C-PTSD, ADHD, Anxiety and Depression.
He has changed my medication according to my experience with it, including removing benzodiazepines from the prescription, lowering the dose of antipsychotic treatment and adding Modafinil as ADHD treatment in line with my history of stimulant abuse (the first line treatment in the UK includes Methylphenidate and Lisdexamfetamine). As follows:
Modafinil 200mg AM 100mg at noon
Chlorpromazine 25mg at night
Gabapentin 300mg three times a day
Pregabalin 300mg twice a day
I would note that there have been mentioned concerns over two different Gabapentinoids, but this is a result of careful consideration of my history with chemotherapy causing residual neuropathy as well as his experience of synergistic effects when combined. I personally do not experience any adverse reactions from this combination.
I am confident in his abilities and wisdom, and I have an appointment with him this weekend to discuss some concerns over depressive symptoms which have presented very suddenly over the past couple of weeks. I have experienced a sudden change at home which has resulted in some passive suicidal ideation, which I do not wish to go further if anything at all.
The depression has been pervasive over the course of my whole life, but I have not experienced much of it for 2-3 months previous to this episode, and it concerns me as I know a passive thought for me can quickly turn into an active plan as my experience shows, and I wish to be prepared so I have made an appointment. My concerns stem from my history of paradoxical reactions to a lot of medications initiated in my treatment, including:
Intense paranoia from Fluoxetine / Prozac 20mg
Mania and aggression from Mirtazapine 15mg
Suicidal ideation from Amitriptyline 25mg
Depression from Clonazepam 2mg / Diazepam 5-10mg
Hallucinations from Chlorpromazine 600mg
Anxiety and paranoia from Prochlorperazine 10mg
Suicidal ideation and crying from Olanzapine 7.5mg
Suicidal ideation from Quetiapine XR 150mg
Parkinsonism and impulsivity from Aripiprazole 10mg
I have had conducted careful research into any solution to the problem of the acute crisis that I have experienced in the past, which usually involves intense aggression, impulsivity, self harm (including and not including drug abuse, although as someone in recovery I doubt this would be a problem), agitation, isolation, and occasionally it has involved suicide attempts.
The medication that draws my attention is Levomepromazine. I have had much experience with this, first given for antiemesis as an infusion where I felt extreme relief from stress and a sudden change in thinking. I no longer experienced the rage that plagued me as a child and I stopped wanting to hurt people and myself. Since then, I have been on and off it either as a 25mg PRN, taken daily as an adjunct to my other therapy in doses ranging from 25mg once daily to 250mg daily in two divided doses with different effects based on the other medications I was taking.
In a state where I feel like the options available are death or violence, I personally think this would get me out of it, but I am aware that I may not be seeing the whole picture.
I understand nothing will replace the decision made by my psychiatrist, although I was wondering if anyone has anything they believe I should present to him as well as this information when I see him?
Any responses would be greatly appreciated, and I wish you all well.

Hey everyone. I just wanted to preface this with the fact that I’ve tried multiple different antidepressants. I’ve tried Lexapro, Prozac, Wellbutrin, and Amitriptyline (AMI) & have even been prescribed birth control to help with the possibility of me having PMDD. At one point I took Wellbutrin, Prozac, AMI, and BC together. As of now I only take Wellbutrin and AMI. I stopped the others because I felt like it really affected me in a negative way. My anxiety got much worse, and my libido dropped significantly. Wellbutrin has been a lifesaver for me, depression wise, and I think it’s my miracle antidepressant. With that being said, it doesn’t help much for anxiety. I suffer from OCD, Depression, and I have anxiety attacks which occur more frequently when I am under a lot of stress (especially right now with my husband being deployed). I have tried expressing to my doctor that I need something specifically to help ease my anxiety (attacks). She has prescribed me with Hydroxyzine but all that does is make me groggy and I’m not a fan of it. I want to ask for something that is more case by case rather than an SSRI or SNRI. I’m afraid to ask for something close to a benzodiazepine as I’m only 22 and doctors are pretty weary nowadays prescribing them in general. I’m not sure if I’m asking more for advice/guidance or reassurance that I need something a little bit stronger than an antihistamine lol. Anything helps, and I appreciate all feedback!! Thank you

Hi all,
I’ve posted a similar question here before.
But my first time considering trying seroquel, all previous experiences have been with SSRI’s.
I’ve tried Lexapro, Prozac, Zoloft and Amitriptyline. All extremely low doses (lower than the lowest dose you can get) and I always have very strong side effects.
I’m extremely hesitant to try seroquel, but no matter what I try - living extremely healthily, improving gut health, exercising/meditating, facing my issues - it seems I clearly do have an imbalance with emotional reactivity that I need assistance with.
On a day to day basis my emotions can be vastly different, and it feels very out of my control. To the point I am surprised I am not dead multiple times over.
I have had a stroke in right frontal lobe, the part of the brain that regulates emotion.
I’ve been “diagnosed” with BPD by one psychiatrist, but ADHD by another. So I’m extremely skeptical of previous diagnoses.
So my question is -
TLDR: anyone else have issues with emotional dysregulation and also a high sensitivity to drugs? Has Seroquel helped? Have you tried other drugs? How did they compare?
Thanks

Hi everyone. Over the last two months I have been having these episodes of panic attacks while trying to fall asleep. It’s so bad to the point where I feel like I am floating from being so tired. I am a nurse and can run off a few hours of sleep when I’m at work I am wide awake but running on caffeine and alanis…I stop with the caffeine around 2pm sometimes I push thru and won’t have an energy drink. I see a psych NP because I struggle, I have bipolar 2, anxiety, depression, OCD. I am in CBT therapy. I take Wellbutrin and Prozac in the AM, I take lamictal, namenda, and propranolol at bedtime with the amitriptyline. I don’t know what triggered these episodes. I have always had issues with sleeping but the last 2-3 months has been god awful. I have used up a lot of sick time because of it, I work day shift and if I’m awake past a certain time my body kicks back in to night shift mode and it fucks me up. I’m worried about being fired over it. I have tried multiple medications, trazodone (stopped working), seroquel (bad hallucinations where I end up screaming and throwing things), amitriptyline (this one works to a certain extent but helps with my migraines), ambien (slept walked and ended up on the basement floor with no recollection), Ativan (mostly used for severe panic attacks so I don’t use it often I don’t want to be reliant on it, hemp seed oil (trash), meditation, yoga, exercise in the afternoon and days off, magnesium supplements There are days where I am so exhausted and go right to sleep but when I go to lay down I am wide away ready to go. It sucks so much it’s almost like I get a second wind and end up awake until 2am and eventually I will pass out. I’ve tried ready and I crochet to wind down at bedtime. I don’t watch TV while I’m trying to sleep, I run a fan because the noise will help sometimes or play rain sounds on my Alexa. I really need some help and advice, thank you for reading this post ❤️

Hi everyone. Over the last two months I have been having these episodes of panic attacks while trying to fall asleep. It’s so bad to the point where I feel like I am floating from being so tired. I am a nurse and can run off a few hours of sleep when I’m at work I am wide awake but running on caffeine and alanis…I stop with the caffeine around 2pm sometimes I push thru and won’t have an energy drink. I see a psych NP because I struggle, I have bipolar 2, anxiety, depression, OCD. I am in CBT therapy. I take Wellbutrin and Prozac in the AM, I take lamictal, namenda, and propranolol at bedtime with the amitriptyline. I don’t know what triggered these episodes. I have always had issues with sleeping but the last 2-3 months has been god awful. I have used up a lot of sick time because of it, I work day shift and if I’m awake past a certain time my body kicks back in to night shift mode and it fucks me up. I’m worried about being fired over it. I have tried multiple medications, trazodone (stopped working), seroquel (bad hallucinations where I end up screaming and throwing things), amitriptyline (this one works to a certain extent but helps with my migraines), ambien (slept walked and ended up on the basement floor with no recollection), Ativan (mostly used for severe panic attacks so I don’t use it often I don’t want to be reliant on it, hemp seed oil (trash), meditation, yoga, exercise in the afternoon and days off, magnesium supplements There are days where I am so exhausted and go right to sleep but when I go to lay down I am wide away ready to go. It sucks so much it’s almost like I get a second wind and end up awake until 2am and eventually I will pass out. I’ve tried ready and I crochet to wind down at bedtime. I don’t watch TV while I’m trying to sleep, I run a fan because the noise will help sometimes or play rain sounds on my Alexa. I really need some help and advice, thank you for reading this post ❤️

Hi everyone. Over the last two months I have been having these episodes of panic attacks while trying to fall asleep. It’s so bad to the point where I feel like I am floating from being so tired. I am a nurse and can run off a few hours of sleep when I’m at work I am wide awake but running on caffeine and alanis…I stop with the caffeine around 2pm sometimes I push thru and won’t have an energy drink. I see a psych NP because I struggle, I have bipolar 2, anxiety, depression, OCD. I am in CBT therapy. I take Wellbutrin and Prozac in the AM, I take lamictal, namenda, and propranolol at bedtime with the amitriptyline. I don’t know what triggered these episodes. I have always had issues with sleeping but the last 2-3 months has been god awful. I have used up a lot of sick time because of it, I work day shift and if I’m awake past a certain time my body kicks back in to night shift mode and it fucks me up. I’m worried about being fired over it. I have tried multiple medications, trazodone (stopped working), seroquel (bad hallucinations where I end up screaming and throwing things), amitriptyline (this one works to a certain extent but helps with my migraines), ambien (slept walked and ended up on the basement floor with no recollection), Ativan (mostly used for severe panic attacks so I don’t use it often I don’t want to be reliant on it, hemp seed oil (trash), meditation, yoga, exercise in the afternoon and days off, magnesium supplements There are days where I am so exhausted and go right to sleep but when I go to lay down I am wide away ready to go. It sucks so much it’s almost like I get a second wind and end up awake until 2am and eventually I will pass out. I’ve tried ready and I crochet to wind down at bedtime. I don’t watch TV while I’m trying to sleep, I run a fan because the noise will help sometimes or play rain sounds on my Alexa. I really need some help and advice, thank you for reading this post ❤️

I've been on Ami since October of 2020. It was original prescribed to me for insomnia and night time anxiety after a close friend died. It worked great for awhile, but for the last year I've been once again struggling with insomnia and racing thoughts at night plus brain fog and depression (I basically felt tired and frozen all the time). My new psychiatrist told me to stop the Amitriptyline for five days and then start prozac and seroquel.
I stopped the Amitriptyline and after three days I felt mentally 100x better. I had never considered that maybe the meds were the cause of the problem! For the last seven days I've been able to fall asleep without thinking I'm dying, I am actually awake and not angry well before 11am, I haven't felt hungry all the time, my vision isn't as blurry, my eye twitches are gone, and the extreme redness in my face has almost completely vanished. I never even thought that these issues could be related to the amitriptyline and I'm really excited to be getting off of it!
Unfortunately, it feels like my bones/veins are on fire. The pain seems to be progressively getting worse. Advil and Tylenol don't really help. Has anyone else dealt with this? Should I press on and hope it goes away or start taking it again. I haven't started taking the other drugs since I feel so much better. Obviously I'm going to talk to the dr., but curious to hear from folks who have actually taken this med.

68 year old female struggling with anxiety and depression. I was on Prozac for 12 years and it worked great. Then it stopped and the nighttime began. It’s been a year and a half of trying everything under the sun. No success. I just stopped pristiq 4 days ago while starting amitriptyline. I’m currently on 30 mg upping to 50 on Monday. The crying jags are horrible. I’m also on seroquil 50 mg. Has anyone gone through a similar rough patch and came out of it. Any hopeful stories welcome 🙏

So long story short, I was on 20mg prozac for 10+ years(still had anxiety though) .
A few months ago with my doctors advice I weaned down (one every other day for 2 weeks) then switched to amitriptyline, tried this for a few months but it didn't help and my dizziness was worse so me and my doctor decided to go back on prozac
I had to wean down the amitriptyline and now iv started 20mg prozac again
I'm now on day 7 and my anxiety has been insane, it's not great at the best of times but I'm so on edge, constant hot face, can't sleep yet so drained, shivering in bed yet hot and panicky etc, constant worrying thoughts/feelings of doom etc.
I assumed because I'd been on it before this wouldn't happen? But then I don't know if it's the prozac or if it's just me :( feels like I'm going insane

Back story/ anxiety and depression successfully treated with Prozac till it stopped working. Got really bad 1 1/2 years ago and that’s when my tongue started burning. Different sensations daily/ better in am worse at night. Currently taking 25 mg pristiq 50 mg seroquel and 20 mg Amitriptyline 68 year old female. I feel the burning is tied to anxiety. Anyone else know about this or experience it

Hi there,
I have complex constellation of mental health issues including OCD: the predominant form it takes is Pure O (intrusive thoughts of causing others harm or acting in exceedingly inappropriate ways) but I also do checks, particularly of the front door and stove, and it will sometimes take me 15 minutes just to get out the door (that's on the extreme end--but I rarely, if ever, can go out with at least checking some stuff).
I'm not going to go too much into my other mental health issues--depression anxiety spectrum stuff--except to say that they are well-controlled by some previous therapy (psychodynamic--I hated CBT tbh) and a drug cocktail including Lamictal, memantine, amitriptyline, and Dexedrine. Sounds like a pretty significant amount of chemicals, but my dosages on all of them are low and I'm very happy with the combo: I don't feel dulled or drugged or anything like that, really.
Those drugs in conjunction really helped with the other issues. I wouldn't say they did nothing for the OCD, but it's been the most treatment-resistant. I also underwent ketamine therapy for awhile, which probably had the most robust effect on the OCD. The effect was transient, however, and I started getting diminishing returns--eventually it didn't do much for it any more.
Now you might guess from this profile that I'd benefit from a SSRI. I have tried one (Prozac), of course, years ago and before any of this other stuff was in the system.
But I absolutely detested it. Unlike the combo described above, I felt really drugged on even a quite low dose and I seemed to get all the side-effects in spades. It also impaired my ability to do some things that are really important to me (writing, in particular). It had positive effects but I found it intolerable.
I also am very happy with the amitriptyline, which has a litany of other positive effects for my case. I've tried lots of antidepressants and this has been the only one that's felt even close to right. I'm not looking to trade it in. I know Clomimpramine is sorta close and could maybe be a good in-between, but I just don't want to mess with what's working.
So anyway, I've read some about Abilify being useful, though pretty much only as an adjunct. I've taken small doses of Abilify before--my psychiatrist gave me some to use during a particularly tough time--and I was actually surprised by how pleasant it was.
Anyway, current doc is willing to prescribe it. I'd be taking the lowest dose possible.
Anyone have any experiences with it especially as mono-therapy (or at least without either a SSRI or Clomimpramine)?

I’ll try to keep this brief…was on Prozac for 12 years for depression and anxiety and it worked great till it stopped. That was a year and a half ago, since then my life has been a nightmare of trying different meds, ECT, an in patient hospitalization (you get the picture) did any of you guys go through this and finally feel better and what worked for you. I’m currently on 25 mg pristiq, 10 mg amitriptyline, 50 mg seroquil which I’m sure dosages will be adjusted. Any positive experiences would be appreciated

Hi all,
I have had a lot of experience with SSRI’s but none with mood stabilisers.
I’ve just been prescribed seroquel, and I am hesitant to try it.
For content, my body is EXTREMELY sensitive to medications and nothing has worked for me thus far.
I’ve tried Lexapro, Zoloft, Prozac and a tri cyclic Amitriptyline. All of which I’ve had quite strong adverse reactions to, and really none of them helped me a whole lot. Prozac was the best, but I couldn’t go up in dose as it was giving me bad dissociative episodes.
It’s been suggested I have Borderline Personality Disorder, however doctors tend to overlook the fact I’ve had a stroke in my right frontal lobe which affects emotional regulation.
All medications I’ve tried I have had to be on EXTREMELY low doses, as in halving the lowest dose you can get.
Could I please get some personal experiences with seroquel from people who may also be sensitive to medications?
My preference is to not be on medications, and work on increasing dopamine and serotonin through diet and fix methylation issues if I have it (currently testing), but I am in quite a severe state and considering medication temporarily.

I've been on many different antidepressents. The ones I remember are Prozac, Luvox, Zoloft, Pristiq, Amitriptyline, and a few more. Also, two mood stabilizers, the first one being lithium. Every single one of these made me feel the same or significantly worse. I stayed on almost all of these for around 1.5-2months minimum at a full dose, sometimes longer.
So far two medications have worked for me. Bupropion, which made me very, very energized the first two weeks, like manic maybe, but I literally passed out on the ground twice at nighttime before bed.
And Lamotrigine/Lamictal, which is also an anti-seizure and bipolar medication. It made me feel absolutely amazing, not particularly manic and it wasn't perfect, but doing things was much easier, and my mood was much better. Unfortunately, I had 4-5 seizures after starting it, which doesn't really seem to be a normal thing to happen. I went to a neurologist and bro was perplexed. Especially since before that I had never had a seizure before. The seizures messed with my head and made me confused & mixing up my words, so I got off of it. Haven't had another seizure since getting off (2-3 months ago).
I guess I'm just kind of wondering if anyone has had a similar experience, in the sense of not having any medications work. Or even like... maybe I have something else that would explain why I'm responding in these ways? Like instead of being Bipolar or depressed I have a secret third thing lol.
I also have ADHD btw, and I don't take any medicine for it atm. It's not super bad, or idk maybe I just manage it well. I have really bad motivation problems which seem like a mix of both depression and ADHD.

Hi, so I am on the autism spectrum and also have ADHD. I also have a bladder condition that is quite painful called interstitial cystitis. My psych doctor was using Prozac off label to help me with my ADHD & also for my Major depressive disorder shich worked great. Then, I developed the interstitial cystitis. My palliative care doctor (I also have stage 4 colon cancer & a bunch of other things going on like lupus, so they manage my meds) asked my psych doctor if we could switch my Prozac to Amitriptyline & then later add on an ADHD med since we add things one at a time yo get a baseline.
Amitriptyline works for interstitial cystitis pain & also depression so I was game because this crap is a nightmare. I hated to go up on the narcotics I'm on, so I figured this was worth a shot (I have lupus & tumors in my colon, lungs, and on my spine at the L4 so I'm already in pain, but this just added a layer of hell). I'm 3 days in & I know it's too fast to really see anything, but man am I hyperfocused on my tasks & I have so much energy. My pain is already cut by a 3rd.
I'm sleeping well when I do get to sleep, but I have trouble getting ro sleep because at the end of the night I'm focusing on what to do the next day. I'm going to up my Vistaril at night because psych said I have wiggle room there. I think that will help if i take abput an hour before bedtime, so i have a plan there. But I have to ask, is this something anyone has experienced? Is the extreme focus, energy, and just general wellness the norm for some people, even a small percentage?
I will be honest, I don't have much faith in meds and was actually expecting the side effects to be awful based on what I read online. I feel like what I imagine most people feel like when they describe being "normal". I can function, stay on task, read a book & not get distracted, listen to a song all the way through without flipping, and my house looks amazing now. My mood is great & my anxiety is on a zero for the first time in years. I hope it's not a placebo effect. I was on Prozac about a week before the switch so I was able to switch over seamlessly with only a 1 day break since I didn't have enough in my system to interact. I feel like this med even made chemo more tolerable this week it seemed. Things aren't perfect because I still all the aforementioned issues, but they're really great. I know reasonably the science said effects will be seen in 4-6 weeks, but this is the only thing I've changed. Any experiences, thoughts, or advice is appreciated.
**Edited for spelling errors.

2 months ago i switched from 20 mg a day of prozac/fluoxetine that i had taken for 10+ years, to 10mg amitriptyline for one week, then up to 20mg (had to take prozac every other day for 2 weeks before switching)
Every since then my dizziness has slowly gotten worse and im curious to know if others have had similar? i dont know whats happening in my brain but my headpain is all over the place, and i feel so off balance. I did have this alot before but its worse now and im wondering if its somehow migraine related?
Maybe because 20mg amitriptyline is not as strong as 20mg prozac? id really appreciate some others stories :)

I had been on 20mg prozac for about 10 years i believe. Me and my docs decided to switch to amitriptyline to see if it helped with my migraines, but iv noticed my dizziness that i usually have seems to be getting worse and im wondering if its the missing prozac, or the amitriptyline
​
I had to switch to prozac 20mg every other day for 2 weeks, and then onto 10mg amitriptyline, which was then upped to 20mg a night and thats what iv stayed on
Has anyone else had this happen?
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Most of us likely know the feeling of brain zaps when you stop an SSRI, that annoying zapping feeling that seems to go across the eyes and more so when you move your eyes side to side…. I have a question about when this can start….
Late December 2023 for 7 weeks in to 2024 I was on Prozac 20mg, I cold turkey quit it due to side affects (motivation/libido) so this was around 45 days ago so over 6 weeks since I quit! The brain zap feeling has only started yesterday and continued today…
Now there are a few other possibilities, I took 10mg amitriptyline for 2 weeks but stopped it around a week ago (again side affects) and in last few days I have taken 1.5mg melatonin for sleep.
Have any of you heard of brain zaps starting 6 weeks after quitting Prozac despite only being on it for just 7 weeks or do we think my brain zap symptoms are more likely something to do with stopping the amitriptyline or even the melatonin?
I really appreciate any responses, thank You

Most of us likely know the feeling of brain zaps when you stop an SSRI, that annoying zapping feeling that seems to go across the eyes and more so when you move your eyes side to side…. I have a question about when this can start….
Late December 2023 for 7 weeks in to 2024 I was on Prozac 20mg, I cold turkey quit it due to side affects (motivation/libido) so this was around 45 days ago so over 6 weeks since I quit! The brain zap feeling has only started yesterday and continued today…
Now there are a few other possibilities, I took 10mg amitriptyline for 2 weeks but stopped it around a week ago (again side affects) and in last few days I have taken 1.5mg melatonin for sleep.
Have any of you heard of brain zaps starting 6 weeks after quitting Prozac despite only being on it for just 7 weeks or do we think my brain zap symptoms are more likely something to do with stopping the amitriptyline or even the melatonin?
I really appreciate any responses, thank You