Propecia case casola

Been on Propecia for 5 years, had tons of regrowth and stabilization since. Thing is, I have to get the brand name from treated.com, which costs me a lot of money.
I can get TEVA generic finasteride 1mg for waaay cheaper at my pharmacy. I've switched a few times, but every time I've shed a bit and the itch came back, so I've chickened out and switched to Propecia again.
I have been relentlessy googling but I can't find any case of anyone get just a little bit of regrowth with Teva finasteride alone, even though people say it's "trusted". In fact, most guys here have written "stabilized and then i lost some volume" so I don't actually think it's working very well at all. Propecia has been a godsend for my aggressive hair loss.
So I'm asking: has any of you had regrowth with Teva? Or at leeeeeast maintained without regressing further? Otherwise I think I'd rather work a couple extra hours a month to not lose my hair. Thank you!

Hair loss can be a challenging experience for many men, impacting not only their physical appearance but also their self-esteem and confidence. Whether it’s thinning hair, receding hairlines, or bald patches, the emotional toll of hair loss can be significant. However, it’s essential to remember that confidence is not defined by the presence or absence of hair. In fact, there are various strategies and techniques that men can employ to boost their confidence and embrace their appearance, regardless of hair loss. In this article, we’ll explore practical tips and empowering strategies to help men navigate the journey of hair loss with confidence and self-assurance. From embracing self-acceptance to exploring cosmetic solutions and building resilience, we’ll uncover ways to reclaim empowerment and embrace personal confidence amidst the challenges of hair loss.

UNDERSTANDING HAIR LOSS

Understanding hair loss is crucial for anyone experiencing this common condition. Hair loss, medically known as alopecia, occurs when hair follicles shrink over time, leading to thinner and shorter hair strands. The most common type of hair loss in men is male pattern baldness, also known as androgenetic alopecia, which is characterized by a receding hairline and thinning hair on the crown of the head. This type of hair loss is primarily genetic and is influenced by the hormone dihydrotestosterone (DHT), which causes hair follicles to miniaturize and eventually stop producing hair.
Apart from male pattern baldness, there are other types of hair loss that men may experience. Alopecia areata is an autoimmune condition that causes hair loss in patches on the scalp, and in some cases, on other parts of the body. Telogen effluvium is another common type of hair loss that occurs when a significant number of hair follicles enter the resting phase simultaneously, resulting in increased shedding and noticeable thinning of the hair.
Several factors can contribute to hair loss in men. Genetics play a significant role, with a family history of baldness increasing the likelihood of developing male pattern baldness. Hormonal changes, particularly fluctuations in DHT levels, can also contribute to hair loss. Other factors such as age, stress, poor nutrition, certain medical conditions (e.g., thyroid disorders), and medications (e.g., chemotherapy drugs, steroids) can also contribute to hair loss in men. Understanding these factors can help individuals better manage and address their hair loss concerns.

COPING STRATEGIES FOR HAIR LOSS

Coping with hair loss can be challenging, but there are various strategies that men can employ to navigate this journey with resilience and confidence. Firstly, self-acceptance plays a crucial role in embracing one’s appearance despite changes in hair. Recognizing that hair loss does not define personal worth or attractiveness is the first step towards building self-acceptance. Positive self-talk and affirmations can help individuals shift their mindset and focus on their inherent value beyond physical appearance.
Exploring treatment options is another important aspect of coping with hair loss. Depending on the type and severity of hair loss, there are various non-surgical and surgical treatments available. Non-surgical options include medications such as minoxidil (Rogaine) and finasteride (Propecia), which can help slow down hair loss and promote hair regrowth in some cases. Additionally, advancements in hair restoration techniques, such as follicular unit transplantation (FUT) and follicular unit extraction (FUE), offer surgical options for men seeking more permanent solutions to hair loss.
Seeking support from friends, family, or support groups can provide invaluable emotional support during the hair loss journey. Sharing experiences and feelings with others who understand can help individuals feel less isolated and more empowered to cope with their hair loss. Additionally, professional counseling or therapy can offer a safe space for individuals to explore their emotions and develop coping strategies to manage the psychological impact of hair loss.
Incorporating stress management techniques into daily life can also help alleviate the emotional burden of hair loss. Practices such as meditation, mindfulness, yoga, and regular exercise can help reduce stress levels and promote overall well-being. By prioritizing self-care and engaging in activities that bring joy and relaxation, men can cultivate resilience and better cope with the challenges of hair loss.

ENHANCING YOUR SELF IMAGE

Enhancing self-image while dealing with hair loss involves embracing various strategies to feel confident and comfortable in one’s skin. For individuals seeking immediate solutions to boosting confidence, exploring cosmetic options such as wigs or hairpieces can provide a temporary boost in self-esteem. Modern wigs are available in a wide range of styles, colors, and materials, allowing individuals to find a natural-looking option that suits their preferences and lifestyle. Wearing a wig can help individuals feel more confident and at ease in social situations while they explore other long-term solutions for managing hair loss.
Experimenting with new hairstyles and grooming techniques is another effective way to enhance self-image and adapt to changes in hair. Consulting with a hairstylist who specializes in cutting and styling thinning hair can provide valuable insights and recommendations for flattering hairstyles that complement facial features and lifestyle. From shorter, cropped styles to longer, layered looks, there are various hairstyles that can minimize the appearance of thinning hair and enhance overall appearance.
Furthermore, focusing on other aspects of personal appearance beyond hair can help individuals feel more confident and attractive. Investing in skincare, grooming, and fashion can elevate overall appearance and draw attention away from hair loss. Maintaining a healthy lifestyle, including regular exercise, a balanced diet, and adequate sleep, can also contribute to a positive self-image and overall well-being. By nurturing physical and emotional health and embracing personal style and grooming preferences, individuals can enhance their self-image and feel empowered to navigate the challenges of hair loss with confidence and resilience.

BUILDING CONFIDENCE

Building confidence while dealing with hair loss involves embracing a holistic approach that focuses on personal strengths, achievements, and overall well-being. One effective strategy is to identify and celebrate personal strengths and accomplishments unrelated to physical appearance. Reflecting on past achievements, talents, and qualities can help individuals recognize their inherent worth and value beyond hair loss. Setting goals and milestones for personal growth and development can also boost confidence and provide a sense of purpose and direction. By setting realistic and attainable goals, individuals can celebrate their achievements and build momentum towards greater self-confidence.
Engaging in fulfilling activities that bring joy and fulfillment is another essential aspect of building confidence. Whether it’s pursuing hobbies, spending time with loved ones, or participating in community events, engaging in activities that bring happiness and satisfaction can uplift mood and enhance self-esteem. Finding purpose and fulfillment outside of appearance-related concerns can help individuals cultivate a strong sense of self-worth and resilience in the face of hair loss.
Seeking professional help from therapists or counselors can also be beneficial for individuals struggling with confidence issues related to hair loss. Professional support can provide a safe space to explore feelings, develop coping strategies, and address underlying insecurities or self-doubt. Therapists can offer guidance and support to help individuals navigate the emotional challenges of hair loss and cultivate a positive self-image.
Ultimately, building confidence with hair loss requires a multifaceted approach that focuses on personal strengths, meaningful activities, and professional support. By nurturing self-esteem and well-being through self-reflection, goal-setting, and engaging in fulfilling activities, individuals can develop resilience and confidence to embrace their appearance and navigate the challenges of hair loss with grace and self-assurance.

CONCLUSION

Boosting confidence while dealing with hair loss is a journey that requires self-reflection, self-acceptance, and proactive steps towards personal growth and well-being. While hair loss can present challenges to one’s self-esteem, it is essential to recognize that confidence comes from within and is not solely determined by physical appearance. By embracing personal strengths, setting meaningful goals, and engaging in fulfilling activities, individuals can cultivate resilience and confidence to navigate the challenges of hair loss with grace and self-assurance. Seeking support from loved ones and professionals, and practicing self-compassion and self-care are also vital components of building confidence and embracing one’s unique beauty. Remember, confidence is a journey, and with patience, perseverance, and a positive mindset, individuals can overcome insecurities and thrive with self-assurance and resilience.

SHOP FOR HAIR LOSS TREATMENTS

Such an agonizing decision to make. You would think after you hit 60 you’ve had your share of difficult choices…. Gleason 4+3 (90% grade 4) One tumour only confirmed by MRI and PSMA Scan. QOL versus relative peace of mind. IRE/Nanoknife versus RALP. One of those decisions you would want someone else to make for you!
As a follow up to this post; A bit long winded. I am not advocating for one treatment option over another; I am not a doctor and each case has its own set of particularities. Just hoping this post may help some brothers who share a similar diagnosis. I live in Canada. I mention this fact as the systems in USA and Canada are different in accessibility and procedures, although I believe the actual quality of the medical care is similar. This forum has been tremendously helpful to me and I warmly thank all its participants. 66 yrs old. Slim, in good physical shape and no other medical conditions. I take propecia (1% finasteride) for years. In December 2023 following annual checkup, my GP was concerned with PSA level at 4.7. Went for another test early Jan and result was 5.47. Unbeknownst to me or my GP at the time, my actual PSA level should have been multiplied by 2, because of the finasteride. I was referred to a urologist who detected a nodule upon DRE. Followed an MRI which showed a single PIRAD 5 lesion at the posterolateral base. Followed a fusion transperineal biopsy. 2 out of 12 cores showed 4+3 Gleason. 2 positive cores came from the one lesion. Grade 4 detected was 90% of sample. I immediately worked very hard to get a PSMA PET Scan. Mid March I received the scan report showing cancer focused in that 1cm nodule and encapsulated in the gland. Considering, I was relieved. Curiously after biopsy PSA dropped to 3.74 (x2 = 7.48) Since my biopsy results, I consulted with 2 surgeons, 2 radiologists, and 4 urologists. Read 3 books on the subject (including 5th edition Patrick Walsh- a must read) and countless you tube presentations and research studies. Not to mention my daily readings on this forum, which again I am very grateful for. After much thought about recurrence risks, side effects, quality of life etc… I’ve chosen RALP. Surgery is scheduled for next week. I hope my choice will be the right one. I’ll be updating outcome.
The only advice I can give anyone who, reluctantly to be sure, joins this brotherhood, is to become your own file manager. Knowledge relieves anxiety. All the very best to all of you.

Results

Fifty cases of male breast cancer have been reported worldwide with the use of 5 mg finasteride (Proscar) and three cases have been reported with the use of 1 mg finasteride (Propecia). Most cases reported with Proscar use occurred within 5 years of starting treatment.
Although the overall incidence of male breast cancer in clinical trials in patients who received 5 mg finasteride was not significantly different compared to patients who did not receive finasteride (7·8 per 100 000 patient-years vs 3·8 per 100 000 patient-years; p=0.328), the data from these trials showed that there was a trend towards male breast cancer occurring more frequently in patients who had received finasteride, than in those who did not.
Link to Study

Hey guys just wanted to share my experience as I can't find anyone else talking about this. I live in Greece and my doctor suggested I take Finasteride 1mg. For context, I had previously been using Minoxidil 5% topical solution for about two years but with not much hair growth. Propecia is not available in Greece so I looked up online to find a seller that would ship the pills to me. I found an online pharmacy and ordered a supply of 270 pills of what I thought would be propecia. They arrived 20 days later shipping from Hong Kong. When I opened the package the pills were out of their boxes(unsealed) and they were labeled "Delpecia". I looked it up online and couldn't find much information. Apparently it's an Indian seller called " Delta Enterprises" but other than that I can't find any other information on them. I contacted the supposed pharmacy that sold them to me and didn't get any response back. Now I'm left scammed with 270 pills that there's no way I can trust to take. I debated taking them at first cause they say they're Finasteride USP 1mg tablets but there's no way I can trust the packaging and don't know if the contents are true. Anyway, just wanted to share in case anyone else has the same experience as me or knows of that Delta Enterprises brand.

Hello everyone!
Just on the train back from London where i had my consultation with Dr Reddy.
I’m a 41 year old male, and i am around a NW2, i have been on propecia for 10 years and it has maintained my hair very well, i just have a receded harline which limits my hair styling options.
I would like to be able to have the generic modern male hair quiff that is short at the back and sides, i can currently achieve this with toppik, and a magical illusion of a styling which takes around 45 mins.
But this is just getting tiresome now, and i’d love to be able to blow dry it up quickly and not have the receded parts showing, and be on with my day.
So Dr Reddy was great, very friendly and down to earth guy, answered all my questions very well, and i felt confident with him straight away.
He was very impressed with my current hair, how well i have maintained on Propecia and also the density, he said my density is extremely high in the highest tier, he said 90 or something (i don’t know how it works)
He said i would need around 1700 gratfs, and it would be a 2 day procedure, but that the 2nd day would be alot shorter where he would only need to do the remaining 300 grafts, but would only charge me for the 1 day.
Because of the density he believes i could achieve what i want, i showed him a pic of a member here called Timcfc, he has an amazing result and i would like to get close to that, he says it shouldn’t be a problem as he would be densley packing it to match my hair behind it.
So, the biggest hurdle i have got now is a mental one, because i appear to have a full head of hair, my family think im a bit crazy for considering it, and i sometimes wonder to myself the same thing.
Only i know the mental torture of having to style it in a certain way and use concealer, but i guess i would be one of the cases on here where people look at my before pics and say “i’d love to have the hair in the before pics” and i totally get that.
The procedure would be something most people would consider i don’t need, but i know if i get a good result it would change my life, to get out bed and be able to style it quickly and be happy with it would be a dream, and i have felt this way for almost 20 years.
But i know if it somehow went wrong and i get a bad result i would hate myself knowing i could of been ok without it.
In a weird way it would be a much easier decision if my hairloss was worse than it is, i go through periods of weeks where i’m really up for having the procedure, and then weeks where i wonder if it’s worth the hassle.
Has anyone got any advice on whether i should pull the trigger? Has anyone been in a similar situation?
Thank you

Hello Community, many of us battle with some form of hair loss and we did extensive studying a research for those people in our community! Medication such as minoxidil and finasteride have been effectively used in cases to treat a stern Baldness in many individuals. Minoxidil is available over the counter as “rogain” and stimulanted hair growth in 2 out of 3 men. Finasteride available as propecia is a prescription drug that slows and stops hair growth in 90% of men and regrowrh in some. Thickening shampoos, and maintaining a healthy life can also play a big part in these and maintaining a healthy lifestyle is often overlooked. Laser therapy is also available to combat against hair loss. For the best results visit a licensed hair specialist, I hope we’ve been of some assistance today!

Hello everyone,
I took low dose naltrexone a year ago for long COVID.
I should mention before I got long COVID I had some ED issues from propecia and also from SSRI use, so I’m a complicated case.
An unexpected byproduct of the LDN was that it brought back nocturnal and spontaneous erections for me which I’d lost for years.
I wish I could have stayed on it to see what further sexual benefits it might have had, but the side effects became untenable. My insomnia got really bad, the vivid dreams were insane, and some other weird issues flared up, like headaches. These are all known sides.
But it did something sexually. It has effects on hormones, neurotransmitters, and the HPA axis. Something happened, I don’t know what, but it helped with erections for months after I stopped the drug.
I took 1.5 mg, which is a low dose. Doctors will often put people on 1.5–4.5 for autoimmune diseases.
I wish I had started at ultra low dose (ULDN) which would have been .1 mg. I have considered going on that again but I’m undecided,
Just wanted to share as it may benefit someone but I would consult a doc. I am not sure it’s a drug that is solely used for ED but I could be wrong.

I’ll preface what I’m about to say with this: my acne, like most people’s here, was painful and unsightly. It drastically lowered my confidence. Taking accutane cleared my face and back and since my last dose a few years ago, I haven’t had to deal with major acne related concerns.
That said, my hair is still shedding (I’m a male). I took my first dose at ~ age 23 and my second dose at ~27. I’m 32 now, so it’s been roughly five years. My hair has considerably thinned over time. For full disclosure, I do have male pattern baldness that started showing up before my first dose, but accutane dramatically increased the rate of thinning/shedding.
Everytime I shampoo/condition, my hands are covered in hairs and it’s been like this for years. Before accutane, I’d never notice anything like this. I know most literature says the hair loss/shedding will generally cease a few months after stopping the medication, but I’m afraid I’m in the 0.1% of cases that’s developed a permanent side effect. Any similar stories/advice?
I’ve been incorporating oils with my conditioner, but I have no idea if that even works. Been taking propecia as well, but again, I have my doubts regarding its efficacy considering the amount of shedding I see. Have not seen a derm about this yet, but I’m planning on setting up a meeting soon.

The pharmacological intervention against androgenic alopecia (AGA), or male-pattern baldness, has seen significant advancements in recent decades. Among the prime movers in this therapeutic frontier is Finasteride (brand name Propecia). A deep dive into its mechanism, backed by scientific studies, offers insights into its prominent role in combatting hair loss.

WHAT IS FINASTERIDE?

Finasteride is an oral medication used for the treatment of hair loss, specifically male pattern baldness (androgenetic alopecia) in men. It belongs to a class of drugs known as 5-alpha-reductase inhibitors. The key role of finasteride is to inhibit the action of the enzyme 5-alpha-reductase, which converts testosterone into dihydrotestosterone (DHT). DHT is a hormone that can shrink hair follicles and lead to hair thinning and eventual hair loss in genetically susceptible individuals. By blocking the conversion of testosterone into DHT, finasteride helps to maintain and sometimes even regrow hair in men with male pattern baldness. It is available in tablet form and typically requires a prescription from a healthcare provider.

HISTORY OF FINASTERIDE

The history of finasteride is a story of scientific discovery and pharmaceutical innovation. In the 1970s and 1980s, researchers at Merck & Co., Inc. embarked on a journey to develop medications for conditions like benign prostatic hyperplasia (BPH), a non-cancerous enlargement of the prostate gland that affects many older men. It was during this period that they identified finasteride as a promising compound.
In 1985, Merck researchers made a breakthrough by pinpointing finasteride’s ability to inhibit the enzyme 5-alpha-reductase. This enzyme plays a crucial role in the conversion of testosterone into dihydrotestosterone (DHT), a hormone associated with prostate growth and male pattern baldness. The discovery of finasteride’s action paved the way for its development as a potential treatment for both BPH and hair loss.
By 1992, after rigorous clinical trials to assess safety and efficacy, Merck received FDA approval to market finasteride as Proscar for the treatment of BPH. This marked the beginning of its journey in addressing prostate-related issues. Subsequently, in 1997, Merck gained another significant achievement with the FDA’s approval of a lower-dose version of finasteride known as Propecia. Propecia became the first oral medication sanctioned for the treatment of male pattern baldness, making it a groundbreaking solution for millions of men experiencing hair loss.
Since then, finasteride, available in the forms of Proscar and Propecia, has become a widely prescribed medication for BPH and male pattern baldness. Its history reflects the pharmaceutical industry’s commitment to developing innovative treatments for common health concerns, ultimately improving the quality of life for many individuals. However, it’s important for users to approach finasteride with awareness of its benefits and potential side effects and to consult healthcare professionals for informed decision-making.

THE ROLE OF DHT IN ANDROGENETIC ALOPECIA

Dihydrotestosterone (DHT) is a hormone derived from testosterone, and it plays a significant role in hair loss, particularly in androgenetic alopecia (male and female pattern baldness). In individuals with a genetic predisposition to hair loss, hair follicles in certain areas of the scalp are sensitive to DHT. When DHT binds to receptors in these follicles, it can lead to a process known as miniaturization. This process causes the hair follicles to shrink over time, resulting in thinner and shorter hair growth cycles. Eventually, the affected follicles may stop producing hair altogether, leading to baldness in those areas. Therefore, DHT is a key factor in the development and progression of hair loss, and treatments often target its effects to mitigate or reverse the condition.

HOW FINASTERIDE WORKS

Finasteride treats hair loss, specifically male pattern baldness (androgenetic alopecia), by addressing one of the key underlying factors: the hormone dihydrotestosterone (DHT). Here’s how finasteride works to combat hair loss:

• Inhibition of 5-Alpha-Reductase: The primary mechanism involves inhibiting the action of the enzyme 5-alpha-reductase. This enzyme plays a critical role in the conversion of testosterone, a male sex hormone, into dihydrotestosterone (DHT). DHT is a potent hormone that can shrink hair follicles in individuals genetically susceptible to hair loss. As a result, hair becomes thinner, shorter, and eventually stops growing.
• Reduction of DHT Levels: By inhibiting 5-alpha-reductase, it significantly reduces the levels of DHT in the scalp and bloodstream. Lower DHT levels lead to a less detrimental effect on hair follicles. Hair follicles can then potentially recover and continue producing healthy hair.
• Promotion of Hair Regrowth: With the reduction of DHT’s influence, it can help reverse the miniaturization of hair follicles. Miniaturization is the process by which hair follicles become progressively smaller and produce finer, shorter hairs. By slowing or stopping this process, finasteride allows for the regrowth of thicker, longer, and healthier hair.

It’s important to note that it is typically taken as a daily oral medication. While it can be effective in promoting hair regrowth, its results may vary among individuals, and it is not a cure for hair loss. Additionally, its effects are usually most noticeable on the crown and top of the head, and it may not be as effective for receding hairlines. It’s essential to consult a healthcare provider or dermatologist before starting treatment to discuss its suitability, potential side effects, and expected outcomes.

EMPIRICAL EVIDENCE

• Pivotal Clinical Trials: A landmark double-blind placebo-controlled study over two years, encompassing over 1,500 men with AGA, revealed that Finasteride users experienced significant improvements in both scalp hair count and perceived hair density, compared to the placebo group.
• Extended Efficacy Analyses: Subsequent research spanning five years reinforced Finasteride’s enduring efficacy. Here, not only was the progression of hair loss arrested in a majority of participants, but a substantial fraction also documented appreciable hair regrowth.
• Biochemical and Histological Evidence: Biopsies from participants of clinical trials showcased a notable increase in the number of anagen hair follicles in Finasteride-treated scalps. Simultaneously, DHT concentration measurements validated the drug’s inhibitory effect on the androgen.

RESULTS

The results of finasteride can vary from person to person, and it’s important to manage expectations when using this medication for hair loss. Here are some general outcomes associated with finasteride use:

• Slowed Hair Loss: Finasteride is often effective at slowing down the progression of male pattern baldness (androgenetic alopecia). It can help prevent further hair loss in many individuals, which is an important benefit.
• Hair Regrowth: Some individuals may experience partial hair regrowth while using finasteride. This regrowth typically occurs in areas where hair follicles have become miniaturized but are not yet completely dormant. It may result in thicker and longer hair.
• Improved Hair Thickness: Even without significant regrowth, many users report that their existing hair becomes thicker and healthier while on finasteride. This can contribute to a more aesthetically pleasing appearance.
• Maintenance of Hair: For some users, finasteride helps maintain their current hairline and density, preventing further thinning or balding.
• Visible Results Over Time: It’s important to note that results with finasteride are not immediate. It usually takes several months, typically around three to six months or even longer, to notice any significant changes in hair density or regrowth.
• Variable Responses: Not everyone responds to finasteride in the same way. While many users see positive results, others may experience limited improvement or no change in their hair loss.
• Continued Use Required: To maintain the benefits of finasteride, individuals typically need to continue taking the medication indefinitely. Discontinuing its use may lead to the gradual return of hair loss.

HOW TO USE

Finasteride is typically taken as an oral medication to treat male pattern baldness (androgenetic alopecia). Here are general guidelines on how to use finasteride:

• Consult a Healthcare Provider: Before starting finasteride, it’s crucial to consult with a healthcare provider, preferably a dermatologist or a healthcare professional experienced in hair loss treatment. They will assess your specific condition and determine if finasteride is a suitable option for you.
• Prescription: Finasteride is available by prescription only. If your healthcare provider recommends it, they will write a prescription for the medication.
• Dosage: The standard dosage of finasteride for male pattern baldness is 1 milligram (mg) per day. This is the dosage typically prescribed to slow hair loss and promote regrowth. It is available in tablet form.
• Consistency: Take finasteride at the same time each day to maintain consistent levels of the medication in your system. It can be taken with or without food.
• Follow Your Healthcare Provider’s Instructions: Always follow your healthcare provider’s instructions for using finasteride. Do not take more or less than the prescribed dose, and do not stop taking it without consulting your healthcare provider.
• Be Patient: Finasteride takes time to produce noticeable results. It can take several months, often three to six months or longer, before you see significant changes in hair density or regrowth. Continuously taking the medication is essential for maintaining its benefits.
• Regular Follow-Up: Your healthcare provider may schedule regular follow-up appointments to monitor your progress and assess the effectiveness of finasteride in your case. These appointments are essential to ensure the medication is working as intended.
• Continued Use: To maintain the benefits of finasteride, you typically need to continue taking the medication indefinitely. Discontinuing its use may lead to the gradual return of hair loss.

SAFETY AND SIDE EFFECTS

Finasteride, a medication used to treat male pattern baldness (androgenetic alopecia) and benign prostatic hyperplasia (enlarged prostate), may have side effects. It’s essential to be aware of potential side effects and discuss them with your healthcare provider before starting the medication. Common side effects of finasteride include:

• Sexual Side Effects: Some users may experience sexual side effects, which can include decreased libido, erectile dysfunction, and ejaculation disorders. These side effects can be concerning for some individuals and may persist even after discontinuing the medication in rare cases.
• Breast Tenderness or Enlargement: Some users may notice breast tenderness or an increase in breast size (gynecomastia). This side effect is typically reversible upon discontinuation of finasteride.
• Allergic Reactions: Although rare, some individuals may experience allergic reactions to finasteride, such as rash, itching, swelling, severe dizziness, or difficulty breathing. Seek immediate medical attention if you suspect an allergic reaction.
• Depression and Mood Changes: In some cases, finasteride has been associated with mood changes, including symptoms of depression and anxiety. If you experience significant changes in mood or emotional well-being while taking the medication, consult your healthcare provider.
• Other Less Common Side Effects: Some users may report less common side effects, including testicular pain, testicular swelling, and general discomfort in the genital area.

CONCLUSION

Finasteride’s molecular action, centered around the inhibition of DHT synthesis, offers a compelling and scientifically validated approach to combatting AGA. Its success story, underpinned by a combination of biochemical, histological, and clinical evidence, cements its role as a cornerstone in AGA therapy.
References:

• Kaufman, K.D., et al. (1998). Finasteride in the treatment of men with androgenetic alopecia. Journal of the American Academy of Dermatology, 39(4), 578-589.
• Leyden, J., et al. (2004). Finasteride in the treatment of clinical benign prostatic hyperplasia: A systematic review of randomized trials. BMC Urology, 4(15), 22-30.
• Whiting, D.A. (2001). Male pattern hair loss: Current understanding. International Journal of Dermatology, 40(8), 469-477.
• Olsen, E.A., et al. (2002). The importance of dual 5α-reductase inhibition in the treatment of male pattern hair loss. Journal of the American Academy of Dermatology, 46(6), 856-862.

Note: Always seek professional medical advice before starting any treatment.

I'm trying to understand the mechanism of action (aka "category") of most of the hair-loss treatments, and which treatments are in which category. (Because I like to understand the mechanism of action of any treatment I use AND know my other options within that category, in case one treatment doesn't work.)
With that said, can anybody help me with answering...
QUESTIONS:
1-Is it true that hair loss treatments generally fall in to one of two categories:

1. ANTI-ANDROGENS and
2. GROWTH STIMULATORS?

Or am I missing a category/mechanism of action?
2-Are there other major hair loss treatments that don't fall into either one of these categories, that I am missing? Mistakes/misunderstandings of what I've written below?
--------------------------------------
So far it seems like the main categories of hair-loss treatments fall into:
1-ANTI ANDROGENS (these seem to work mainly by STOPPING HAIR LOSS caused by DHT as opposed to causing hair growth. Is this correct?)
5-Alpha-Reductase Inhibitors

• finasteride
• dutasteride
• Propecia

Androgen receptor agonist

• Spironolactone
• RU58841

2-GROWTH SIMULATORS - (These seem to actually cause hair to grow more, possibly by more blood flow, increased growth factors, etc)
Minoxidil Seems to be in a category of its own, since nobody truly knows why it works, they just know that it Reverses the miniaturization of follicles. Increases blood flow around follicles. Stimulates follicle movement to growth phase.
Rosemary oil Anecdotal evidence and a few studies indicate that Rosemary oil can increase capillary perfusion (meaning blood flow) to the scalp which may be the reason it is able to help with hair growth
Microneedling Causes body to increase blood flow and growth factors.
LLLT (low level laser therapy) Causes body to increase blood flow and growth factors.
WHAT ELSE?
Any other major "mechanism of action" categories to add? Any other major treatments to add?
Apologies for any mistakes and incorrect assumptions in my question. I'm trying to figure out what I don't know. Thanks in advance for any insights!

I'm trying to understand the mechanism of action (aka "category") of most of the hair-loss treatments, and which treatments are in which category. (Because I like to understand the mechanism of action of any treatment I use AND know my other options within that category, in case one treatment doesn't work.)
With that said, can anybody help me with answering...
QUESTIONS:
1-Is it true that hair loss treatments generally fall in to one of two categories:

1. ANTI-ANDROGENS and
2. GROWTH STIMULATORS?

Or am I missing a category/mechanism of action?
2-Are there other major hair loss treatments that don't fall into either one of these categories, that I am missing? Mistakes/misunderstandings of what I've written below?
--------------------------------------
So far it seems like the main categories of hair-loss treatments fall into:
1-ANTI ANDROGENS (these seem to work mainly by STOPPING HAIR LOSS caused by DHT as opposed to causing hair growth. Is this correct?)
5-Alpha-Reductase Inhibitors

• finasteride
• dutasteride
• Propecia
• Rosemary oil also a growth stimulator (according to some sources)

Androgen receptor agonist

• Spironolactone
• RU58841

2-GROWTH STIMULATORS - (These seem to actually cause hair to grow more, possibly by more blood flow, increased growth factors, etc)
Minoxidil Seems to be in a category of its own, since nobody truly knows why it works, they just know that it Reverses the miniaturization of follicles. Increases blood flow around follicles. Stimulates follicle movement to growth phase.
Rosemary oil (ALSO A 5AR inhibitor) Anecdotal evidence and a few studies indicate that Rosemary oil can increase capillary perfusion (meaning blood flow) to the scalp which may be the reason it is able to help with hair growth
Microneedling Causes body to increase blood flow and growth factors.
**LLLT (low level laser therapy)**Causes body to increase blood flow and growth factors.
WHAT ELSE?
Any other major "mechanism of action" categories to add? Any other major treatments to add?
Apologies for any mistakes and incorrect assumptions in my question. I'm trying to figure out what I don't know. Thanks in advance for any insights!
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UPDATE:
Found this article that lists several other "categories", mainly Corticosteroids and Antifungal, and antibioticshttps://nyulangone.org/conditions/hair-loss/treatments/medication-for-hair-loss
If anybody can think of other categories or types, please do share.
UPDATE 2:
I just found this video, and he corroborates that there are 2 main hair growth categories (anti-androgens, and hair growth stimulators, as I suspected), but he adds another one: the prostaglandin category https://youtu.be/TzcptIPNyX4?t=295
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PS: I know this is by no means a conclusive list of treatments - there are hundreds. What I'm more looking to determine are the major CATEGORIES of hair loss treatments, not each of the hundreds of individual treatments themselves, just to clarify.
Also, I'm not trying to be overly pedantic about this, I just think it's helpful to understand why I would be taking each treatment, and to understand when I am doubling up in one "category" and potentially missing another category.

did you have any issues with finasteride after re-starting it after the 1st time? First time I went 6 months on propecia with no issue but after stopping that first time every time I try to re-start the medication it gives me weird stomach pain and back pressure always after 2-3 months. Bare in mind that all the times I tried to re-start fin I had dutasteride still in my system which was not the case the first time.

I took that white for seven ducking years I haven't had a sex life ever . Before fin women wanted me but i was a shy introvert and didn't want to get down On fun I dated but never felt raw list With pfs I got my .On I back but never even ducked a boiler just walked to instahram.girls and open Now.my mojo is gone and won't come backs unless we get a treatment.
And I have a court summons for sending or allegedly sending threats and stuff tI those office cunts that picked in me for having pfs
Should I just off myself I am like that Lazarus guy interns of sevrity of symptoms Went frok.looking young and being horny, not havingofs essentially, to fuck ed
I also resent Propecia Help as getting my username and story dissed I. There led to all the stress and eventually then crsah. And I terms of recovery if I had by a fine to a ur o instead of looking in there and fucking displeasure if have been cured in TRT years ago I was a very mild recovered case with visual list and normal genitals

I did a study in 2011 and was still in not great shape two years after the crash but was over the worst. Then got libido back by 2013 all was good til a horrendous office experience when my PFS was doxxed amidst other shit. Anyway I stopped looking at propecia help and then crashed hard in 2022 having been a mild case. And what do I find? We are nowhere near the cure still and don't even have a fucking biomarker for this let alone and idea of what went wrong. Absolutely pathetic leadership of this community for over a decade. The role should have been delegated if precious awor found it too much to cope with

Note: the post below was originally shared in a facebook group, and was not initially intended for doctors or medical professionals, hence some of the language
33 y/o male / 6'0 - 180 lbs / non-smoker / don't drink or use recreational drugs / regular meds include Resolor (Prucalopride - a prokinetic for constipation) and Propecia (Finasteride)
Please excuse the typos and grammatical errors. As usual, I’m writing this post in the midst of the never-ending brain fog/cognitive impairment, so it’s a bit hard to articulate. I’ll warn you in advance: the post is going to be a bit all-over-the-place/lacking structure/organization as I’m just trying to get all the info out there while my brain is BARELY working.
Anyway, I posted about a week or two ago about my brain fog and received a ton of replies, for which I’m super thankful (I tried to respond to everyone, but then I came down with a nasty case of gastroenteritis / stomach flu that really set me back so apologies if I didn’t reply to your comment).
Regardless, I wanted to follow up to my previous post, as I’ve had a few revelations since. With that being said, I want to preface my post by saying that I typically don’t post twice in such a condensed time span, as I know how many others are suffering/struggling with their own health issues, but these days, I don’t really have much of a choice.I’m not going to delve into my life story, but I will say is this: Have you ever had a moment / moments in your life where you absolutely need something to happen? Like if it doesn’t, it won’t just be an inconvenience or hassle, but rather it could upend your entire life…that’s where I’m at. (And yes, I realize stress and anxiety are not great over one’s overall health, but sometimes it’s impossible to avoid them. With that being said, considering my current situation, I feel as though I handle the stress and anxiety reasonably well, so I want this post to please focus on the physiological/scientific aspect of what might be at play, as opposed to the emotional)
As I’ve written about in the past, this brain fog (and I really do hate calling it “brain fog” as it’s more of a dementia-esque cognitive dysfunction/disorientation) has wrecked every aspect of my life: professional/personal/marriage/literally everything. We need our brain to function, it’s that simple. I’ve gone from a high-performing-happily-married-late-20-something-year-old to a barely-functioning-professionally-inept-marriage-at-risk-33-year-old. I’m a shell of myself.
7+ years of the fog, and I find myself at a point where it’s not that I’d LIKE to get better, but rather I NEED to get better or things are going to take a very nasty turn for the worse.
Now, let me clarify, this is not a cry for help (well I guess in a sense it is), but I’m the type to give up (although this journey has certainly taught me not judge anyone that has such thoughts as you never know what circumstances may have led them to that point). I’m a fighter, and I’ve dealt with quite a bit of adversity in my lifetime, particularly in the last decade, and I’ve never shied away from the hardship…
.…with that being said, this obstacle is different to previous ones, in the sense that I need my brain to work to dig myself out of this mess. Otherwise, I’m like a person with no arms trying to lift weights (Maybe not the best analogy, and I don’t mean to offend anyone who may be in limbless in this group, but it’s the analogy that comes to mind). The point being it’s doable but incredibly difficult.
Now before I get to my recent revelation(s), let me provide a bit of context:
I’ve had brain for about a decade that’s seemingly gotten progressively worse over the past 7 years. It used to be most noticeable after eating, so I always assumed it was a gastro-issue, and spent years seeing gastro docs, trying every diet (and to a lesser extent: supplement) under the sun with no real improvement. Fast forward a few years, I started to notice that I’d get the brain fog after drinking liquids like watejuice/etc. Fast forward about a year, I noticed that I would get the brain fog (albeit to a lesser extent) even after just swallowing my own saliva…Fast forward about six months, I noticed that I get the brain fog (albeit to a lesser extent) even when I take a deep breath through my mouth)
Now again, this is not the type of brain fog/cognitive disorientation that comes about and clears within a matter of minutes or even hours. This fog pretty much stays with me for at least a few hours to throughout the entire day, and renders me effectively incompetent. It’s as thought there’s an invisible barrier in my brain, and it becomes hard to think, speak (I’ll start slurring words), recall/remember, etc. - it’s almost like a high-speed computer running on an old-school modem/router…laggy, slow, simply not functional. Such fog makes everything difficult…working, conversing with my wife, completing basic functions like driving, etc. I effectively become a cognitive vegetable once the fog comes about. THE ONLY THING that helps is sleep. I’m at my sharpest, when I wake up in the morning. Once I start swallowing, eating/drinking/breathing through mouth/etc. I slowly get more and more of the fog.
Now, there are some things that alleviate/help LIMIT (not prevent or cure, but simply limit) the fog. The most notable one would be salt. I have to add salt to pretty much everything I ingest if I want to limit the brain-fog. I’m like a mad chemist sprinkling salt on everything I consume. The second would be sparkling wateseltzer, specifically the carbonation inside. As I’ve written about previously, I only consume the upper half the sparkling water bottle, as the carbonation tends to rise to the top of the bottle, and therefore I get less fog from consuming the upper portion but if I keep drinking to the lower half/portion, because there’s less carbonation, I’ll get the fog.
These days, if I really want to function, it’s not only that I don’t eat or drink until the late afternoon/evening (so as to minimize the fog), I try to not even swallow my own saliva. You read that correctly, I literally spit out my saliva so as to swallow as little as possible of it…and yes, I realize how absurd that sounds, but that’s pretty much where I’m at it this point. Imagine not only not being able to eat or drink (even plain regular water), but not even being able to swallow, it’s absolutely maddening.
Now, as I mentioned, I’ve posted once or twice previously, and I’ve always gotten great feedback.
When I last posted, a few people suggested maybe there is some sort of a neurological/swallowing dysfunction/disorder causing the brain fog. Something functional or structural in nature. I’ll be honest, initially, I somewhat dismissed this theory as (in my mind) it didn’t really fit with my symptomatology. If the underlying cause was structural, why does salt help? It didn’t make sense…
Then I started to think about it more and conduct some research (needless to say, I’m no MD or scientist by any means) and it started to get interested. What if there is some sort of respiratory/breathing/swallowing/throat/esophageal dysfunction…?
Just to understand how the brain fog comes about, it usually plays out like this: I’ll swallow something, food/watesaliva/etc., and then I’ll count to two or three…”one one thousand…two one thousand…three one thousand” and then suddenly I’ll get the fog, which almost feels like a pressure/emptiness in my head. It’s really hard to describe the fog (particularly right now as I currently struggle with the fog). It’s hard to tell if it feels like there is a lack of oxygen in the brain, or if it’s just a pressure feeling, or if it feels kind of numb, but what does seem to be evident is that it comes about 2-3 seconds after I swallow/ingest. It’s important to mention that I also get a version of the brain fog (albeit to a lesser extent) when I inhale through my mouth so it doesn’t seem to be strictly-swallowing induced.
So going back to the aforementioned revelation…what if the underlying issue is a swallowing/respiratory/lung issue…? What if when I swallow/breathe, something mechanical is not functioning as it should, and therefore contents (food particles, water bacteria, saliva bacteria, etc.) are either going where they shouldn’t or leaving where they shouldn’t…(I should mention that I don’t feel as though I’m swallowing or breathing incorrectly, like there are no signs of an obstruction or anything getting stuck)
Now again, I’m far from an MD or scientist, so suffice to say I’m not expert in the mechanics of swallowing/breathing but this is why I wanted to post in the group. Many of you are much more well-versed than I am when it comes to the science behind all of this and have given me great direction in the past, so I wanted to get your thoughts on my current theory.
Maybe the salt acts as something sort of disinfectant/antibacterial and when I swallow, whatever contents are going/ending up where they shouldn’t are somewhat mitigated by the protective layer provided by the salt….
Something else that is interesting is when I drink the sparkling water, I don’t so much drink it as I do slurp it (once again, I realize how nuts all of this sounds, but you’ve got to trust me, I’ve tested many many times). If I sort of slurp the sparkling water, as opposed to drink, I seem to get more carbonation/gas out of what I’m drinking, and it lessens the fog…Could it be that the pressure/gas sensation provided by the carbonation is preventing something from opening/going where it shouldn’t during the swallowing process?
I’m going to summarize what I’ve written up until this point into concrete points:
- 7+ years (probably 10+ years) of brain fog/cognitive dysfunction/disorientation that has seemingly gotten worse over the years
- Consuming salt with everything I eat/drink/consume helps somewhat limit the fog (why is that? Trying to work that out…salt has many functions: antibacterial, antihistamine, antinflammatory, disinfectant, etc. - so it’s difficult to pinpoint through which of these mechanisms it’s helping…)
- Slurping sparkling wateselzter instead of drinking watejuice/unsalted liquids seems to lessen the fog(why is that? Is it correlated to the pressure/gas byproduct of carbonation that maybe affects the swallowing process in some way? Does it prevent something from opening that maybe shouldn’t be open?…)
- I feel the fog about 2-3 seconds after swallowing (one one thousand…two one thousand…three one…and then I feel it)…why do I feel it then? Where are we (as human beings) in the swallowing process after about 2-3 seconds? Are swallowed contents in the throat at that point? Esophagus? What sphincter should be opening or closing?
- I get the fog even after swallowing saliva (i.e. no food or water)- Eating food with high protein or fiber seems to somewhat reduce the amount of fog I get after ingestion (not 100% sure about this but it seems to be the case). I’ll even take it a step farther than that…when I don’t chew food thoroughly, I seem to get LESS fog that I when I do chew it thoroughly (and thereby turn it into a more broken down / liquid state…why is that? Is it similar to the sparkling water phenomenon whereby the weight/pressure that comes from the undigested/fibrous/protein-rich food forces something to stay close that is maybe malfunctioning and opening?
- I took Rifaximin (which is used as antibacterial antibiotic for people that have Sibo and other gastro disorders) years ago when I was trying to find a solution to my years and years of constipation (which I have under control these days, so I don’t want to delve into any of that, but rather stay focused on the brain fog) and my wife seems to remember that it helped me with the brain fog….why is that? (Respectfully, I don’t want to hear anything about SIBO as I don’t have SIBO and honestly I don’t even really think the underlying issue is gastro-related, maybe it’s esophageal-related but I think it has very little do with my small intestine). I understand that many people feel better while on antibiotics, but it’s interesting to think about why the Rifaximin specifically helped the brain fog? Is it possible that the antibiotic had some sort of antibacterial/anti-inflammatory effect on my respiratory system/lungs?- I have a dust mite allergy, could that possibly be related to any of this? With that being said, I haven’t come across too many people (if any) with allergies that have a swallowing-induced-brain-fog phenomenon.
- I do often feel like it’s more difficult than it should be to breathe…like my chest/lungs feel heavier than they should. I seem to get winded and fatigued quite easily. There’s a term thrown around a lot known as “air hunger” and this is what I seemingly feel quite often
- I have trouble breathing deeply
- Something interesting that may have absolutely no correlation to any of this: When I sneeze, I have to sneeze out of my mouth and let out almost like a war cry because I feel as though that’s the only way to get it out. Why is that? Is it related to some sort of lung/respiratory weakness/incapacity? I certainly didn’t sneeze like that when I was young…- When I was being test for Dysautonomia/POTS, which technically I don’t have, at least according to current diagnostic protocols, I underwent a test called the HRDB (Heart Rate Deep Breathing Test) during which you they hooked me u with a bunch of sensors to measure my heart rate during deep inhalation/exhalation. Specifically, as I understand it, this test measures heart rate variation during deep breathing to see how well one’s parasympathetic/sympathetic nervous system is working. My heart rate spiked from 72 to 123 during this test, and my doctor said this was the biggest disparity he had ever seen and couldn’t explain it beyond saying it indicates an ABNORMALITY WITH MY PARASYMPATHETIC SYSTEM…with that being said, he said that usually people with dysautonomia have the opposite effect whereby their heart rate drops during this breathing process, and therefore technically I don’t have dysautonomia. Nonetheless, I still think that’s an interesting test result and I’ve actually noticed that I also get the brain fog (albeit to a lesser extent) when I take a deep breath through my mouth. Is it possible that I'm having some type of allergic/asthmathic reaction causing my heart rate to spike?
- As I wrote above, I seemingly get the brain when I take a deep breath through my mouth (albeit to a lesser extent) so it doesn’t even seem to strictly swallowing-induced.
- When I take hot (steamy) shower it seems to help the brain fog a bit. Why is that? Is it maybe because the inhalation of the steam is having anti-inflammatory effect on my lungs/respiratory system/nasal passage?
- I’m fatigued quite often, especially after eating or drinking, where I feel as though I need to sleep. People in the past have suggested ME/CFS (Chronic Fatigue Sydnrome) but even if I do have CFS, that doesn’t really help me much. CFS is a clinical diagnosis (in other words, to my knowledge, there’s no blood test that measures/is used as a diagnostic tool for it). This may be a controversial statement, but CFS reminds me a bit of IBS, where it’s almost like a label given to people (by doctors) who are clearly suffering from symptoms but nothing has shown up in their bloodwork/diagnostic testing. It’s somewhat of an umbrella unexplained-symptoms label that quite a few people have been given. So regardless of whether or not I have CFS, it doesn’t really help my pursuit to figure out the underlying cause.
- I seem to sleep much better when I breathe through my nose than mouth (I imagine this is the case for most people) but my nose is blocked and I’m forced to breathe through my mouth, I wake up the next day feeling as though I barely slept (big-time dark circles under my eyes).- I sleep with my head propped up by a number of pillows as when I used to sleep (more) flat, I would sometimes feel short of breathe and briefly (my body would) convulse (didn’t happen a lot, maybe a few times a month).
- Brain fog is not my only symptom, I do have other issues like many years of constipation (which caused a rectal prolapse - very uncommon in males and not a lot of fun), pelvic floor dysfunction, urinary issues/trouble urinating, an enlarged bladder, IBS, noise sensitivity that leads to headaches, etc. - but (while some of these issues are physically quite uncomfortable to live with) the brain fog is more debilitating than all these issues combined. I can manage around the other issues, but not the aforementioned fog.
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Moving forward, I think the next steps are fairly clear.
I’d like to consult with pulmonologist and allergist/immunologist/ENT doc.
What do you guys think? (Needless to say, none of your replies will be interpreted as medical advice)…Any thoughts or recommendations regarding my current path? Can’t tell you how appreciate I am for these reddit groups, as I feel like each time that I post, I get useful info (certainly much more useful than what I get from the docs) that helps me down (what I hope to be) the right path
Thanks in advance

its my first time posting here and from personal experience what i’ve noticed is that when i started taking finasteride propecia brand for 3 months to be exact i noticed my hair fall completely stopped and noticed alot of gains i was 18 at that time and when i went back to my pharmacy they ran out of propecia so i had to take the other brand known as prohair its a made in jordan finasteride and my hairfall started again i took it for 6 months and slowly saw my hairfall continue again with an even faster rate i didn’t know if it was cause of the brand cause everyone said online they have the same active ingredient however i switched back to propecia again to be sure and my hairfall stopped again thank god this may not be the case for everyone but i just wanted to let you know my personal experience cheers

Hello everyone. My hair has thinned significantly over the last 2 years. So I decided to start taking 1 mg of Propecia every day. After just 2 days I had pain around my nipples, especially on the left side. These pains were very strange and I had never had them before. I also had pain around my testicles and my entire penis. I read that such pain occurs, but I continued to take 1 mg / day. However, I had to stop on day 7. I noticed that my left breast had become significantly larger, probably due to the fat accumulated there, as it is much larger than the right side. In addition, my erection and erection are very weak compared to a week ago. So I had very bad side effects after just a week! I would have continued taking finasteride, but the development of gynecomastia scared me away, and I stopped taking the pill after the 7th day. I would like to continue using this medicine because I care about my hair. And here I have questions for you: what should I do in this situation? Reduce dose to 0.5 mg, 0.25 mg? For example, should I use 1 mg every other day? Maybe I should contact my doctor? Is there a chance that my side effects will go away? As for the enlarged left breast, it always seemed bigger to me, and maybe it became even bigger under the influence of finasteride? Which doctor should I see in this case? I will also add that I am very slim, I weigh 145 lbs, my height is 5ft 11.65354in.