Colchicine and allopurinol
Allopurinol
2021.03.31 03:35 AndrewLonergan Allopurinol
A subreddit for Allopurinol, a medicine that treats gout / Nephrolithiasis and to prevent recurrent calcium stones
2014.01.30 08:37 Familial Mediterranean Fever
A sub-reddit dedicated toward those who share this rare and devastating genetic disorder. This sub-reddit's intention is to discuss and exchange advice on coping with Familial Mediterranean Fever.
2011.10.07 20:48 crilen Gout Sufferers Unite
Also visit us on kbin: https://kbin.social/m/gout Gout Discord: https://discord.gg/kvyxW4S8 Do not ask to be diagnosed!
2024.05.15 20:01 rowdyruffboys Question about lingering pain after a flare
Context: I have been on allopurinol for a couple months and have reduced both purine rich and trigger foods from my diet. A couple weeks ago, I ate some marinated crab with roe, which hadn't been an issue, especially in moderation, but this ended up triggering the worst gout flare I've ever had in my life. My foot was practically double the size of the other. I was able to secure some colchicine for more rapid relief.
Fast forward to two weeks after the gout flare, my ankle, which is where the attack was centered on is exhibiting a couple of weird things and I wanted to get a bit more information on whether it's lingering symptoms of gout, or something worse.
Symptoms:
Does this seem normal? I obviously don't want to suspect joint damage, tissue damage, or something worse. I realize I should probably go see a doctor before my insurance runs out, but wanted to see if anyone else has experienced something like this, and whether I would be able to wait it out.
Happy to provide additional information if requested
submitted by rowdyruffboys to gout [link] [comments]
Fast forward to two weeks after the gout flare, my ankle, which is where the attack was centered on is exhibiting a couple of weird things and I wanted to get a bit more information on whether it's lingering symptoms of gout, or something worse.
Symptoms:
- During the flare, it seemed like my ankle was bruised. While mostly gone, the ankle still looks slightly darker
- When I am sitting down in a chair and I try to raise and/or extend my leg out, a stinging pain shoots up from the ankle near the joint
- This is the main concern. It seems like I've lost a significant amount of mobility
- If i were to stretch my legs standing up, feet facing forward with my left knee bent and right leg extended, the area under my ankle joint exhibits the same pain
- When I run, using the balls of my feet, the downward impact hurts the same ankle area
Does this seem normal? I obviously don't want to suspect joint damage, tissue damage, or something worse. I realize I should probably go see a doctor before my insurance runs out, but wanted to see if anyone else has experienced something like this, and whether I would be able to wait it out.
Happy to provide additional information if requested
2024.05.14 20:07 SirTypical5030 Elbow, Keto, flare up nagging
So I am almost 44 was diagnosed with gout about 12 years ago. Been on allopurinol since that initial diagnosis and have often gone 12-18 months between flare ups sometimes longer once even almost 3 years in between. I have always eaten a decent diet but I recently started trying to lose weight and live an even ealthier lifestyle. **Alcohol 1-2 if not 3 days a week was being consumed now down to couple times a month. Playing pickleball, more hiking/biking and less drinking since January 1st as a New Year’s resolution. I also started Keto with the wife and have been doing Keto and intermittent fasting since then (was fully keto through March now eating Keto about 90% of meals/snacks). I have lost 27lbs and am pretty much at my goal weight. Currently weigh 188 (goal was 185) at 6ft tall. Keto makes me feel fantastic in terms of energy, weight loss has been a huge success. I also supplement with Vitamins, B12, D, calcium, magnesium, daily multivitamin and tart cherry extract almost every single day.
My elbow started bothering me off and on when I switched to keto but was also playing pickleball and doing push ups so generally when I laid off the pickleball/push ups for 3-4 days it got better. Didn’t even think it was gout related at first. I am now going on two weeks with a really bad elbow flare. Took about 6 colchicine after the first 3-4 days when I figured out it was in fact gout and not tennis elbow, and now it just won’t quit. I know you don’t want to keep takin colchicine so I stopped taking it 4 days ago. Usually that knocks it out. Stopped all lifting, exercise using the elbow, pickleball, etc. Feels 75% during the day and on fire at night. Drinking 100 oz of water at a minimum daily.
Everything I read about keto was the diet change would cause flare ups initially in the first few months due to the change in diet but if not smashing red meat and purine rich foods it should regulate back to normal.
Any ideas on things to try to get this knocked out?
Anyone else doing keto and seeing increased flare ups over a prolonged period?
Anyone doing keto long term and seeing it go back to “normal” in terms of flare ups?
Any other suggestions on ways to calm this flare up down?
Anyone else have flare ups in the elbow and have recommendations?
Any help would be appreciated, sorry for the long post kept thinking of more info to add haha.
submitted by SirTypical5030 to gout [link] [comments]
My elbow started bothering me off and on when I switched to keto but was also playing pickleball and doing push ups so generally when I laid off the pickleball/push ups for 3-4 days it got better. Didn’t even think it was gout related at first. I am now going on two weeks with a really bad elbow flare. Took about 6 colchicine after the first 3-4 days when I figured out it was in fact gout and not tennis elbow, and now it just won’t quit. I know you don’t want to keep takin colchicine so I stopped taking it 4 days ago. Usually that knocks it out. Stopped all lifting, exercise using the elbow, pickleball, etc. Feels 75% during the day and on fire at night. Drinking 100 oz of water at a minimum daily.
Everything I read about keto was the diet change would cause flare ups initially in the first few months due to the change in diet but if not smashing red meat and purine rich foods it should regulate back to normal.
Any ideas on things to try to get this knocked out?
Anyone else doing keto and seeing increased flare ups over a prolonged period?
Anyone doing keto long term and seeing it go back to “normal” in terms of flare ups?
Any other suggestions on ways to calm this flare up down?
Anyone else have flare ups in the elbow and have recommendations?
Any help would be appreciated, sorry for the long post kept thinking of more info to add haha.
2024.05.14 03:08 514senica Starting to understand the mental part.
I've been lurking in the community for the past few weeks. I'm on day 23, 49 years old, and following a clean keto diet (don’t fret about the Keto label, it’s just more descriptive than 'whole foods with minimal carbs').
I started a Couch to 5k program in the second week, and aggravated my knee (I had ACL surgery 20 years ago). While my knee has been 'tight,' I've continued to walk but stopped doing squats and pretty much avoided leg days. Unsure of how far to push it, I scheduled a visit to my ortho doc, whom I met with today.
He thinks it could be arthritis from the old injury or it could be gout (I have a history, and tested super high for uric acid a week ago; I started allopurinol and colchicine 5 days ago as a result) or both. Either way, he wants me off it until it settles down, and that only includes minimal walking.
It's a bummer because I'm really starting to enjoy my walks. Not only do I see myself getting faster and feeling stronger, but they're super convenient. I can walk my dogs, do it from home, go with my wife/kids, etc. I'm too stubborn to quit the challenge, so now I'm forced to understand the 'mental' side of it. It’s not just about getting in better shape; it's about rising above adversity and pushing through the challenge, even when conveniences break down.
Anyone know how I can get cardio in without using my legs?
Until I figure it out, my chest/back and arms are going to be huge.
submitted by 514senica to 75HARD [link] [comments]
I started a Couch to 5k program in the second week, and aggravated my knee (I had ACL surgery 20 years ago). While my knee has been 'tight,' I've continued to walk but stopped doing squats and pretty much avoided leg days. Unsure of how far to push it, I scheduled a visit to my ortho doc, whom I met with today.
He thinks it could be arthritis from the old injury or it could be gout (I have a history, and tested super high for uric acid a week ago; I started allopurinol and colchicine 5 days ago as a result) or both. Either way, he wants me off it until it settles down, and that only includes minimal walking.
It's a bummer because I'm really starting to enjoy my walks. Not only do I see myself getting faster and feeling stronger, but they're super convenient. I can walk my dogs, do it from home, go with my wife/kids, etc. I'm too stubborn to quit the challenge, so now I'm forced to understand the 'mental' side of it. It’s not just about getting in better shape; it's about rising above adversity and pushing through the challenge, even when conveniences break down.
Anyone know how I can get cardio in without using my legs?
Until I figure it out, my chest/back and arms are going to be huge.
2024.05.13 16:40 asentienttaco Is it possible I have an AKI?
M. 31 y/o. Take Zoloft, buproprion, allopurinol. Take Gabapentin, propranolol, colchicine, lisinipril PRN. History of depression, anxiety. Resolved issues with obesity, BP, elevated lipids, etc after losing weight.
My eGFR is typically 120. Recently I went to the ER and I noticed my eGFR was 83.
Is this a normal fluctuation? Should I get checked out?
I have always had a pain in my lower back on the right side, but my kidney function has been generally normal.
I am concerned because kidney disease runs in the family.
submitted by asentienttaco to AskDocs [link] [comments]
My eGFR is typically 120. Recently I went to the ER and I noticed my eGFR was 83.
Is this a normal fluctuation? Should I get checked out?
I have always had a pain in my lower back on the right side, but my kidney function has been generally normal.
I am concerned because kidney disease runs in the family.
2024.05.13 02:44 guy_incognito118 has anyone asked doctor to prescribe indomethacin during allo treatment?
Hi everyone, I was prescribed allopurinol 100mg once a day and naproxen 250mg twice a day, and I've been taking both consistently for a week and half. However, for the past couple of days I've been taking 1 allo and 1 indomethacin per day (and I try to keep them a few hours apart) instead of naproxen, because my knee flared up again and the pain was getting worse. It was super annoying, because my second toe started hurting day 3 but got better by day 5, but then my knee started hurting on day 5 too, so Friday night I finally decided to take 1 indomethacin, then for Saturday and Sunday (today) I've been taking allo in the morning and indomethacin with lunch. Basically, question is, I was wondering from people's experience if a doctor would be willing to prescribe indomethacin on an "as needed" basis while you're taking allopurinol if they already prescribed another medication like naproxen?
The indomethacin was left over from my last gout attack that started 3rd week of March, and it went on for most of April, with some of the worst pain and swelling I've ever felt that started in big toe, moved to second toe and other parts of my foot, and once my foot got better my knee flared up.
I had x-ray and bloodwork done in April, confirmed high UA, got prescribed indo to help with flareup, then was told to make a follow up appointment to get on allo once that calmed down. Doc who prescribed allo and naproxen said to stop indo (which I'd already done). I don't know why naproxen with allo instead of more indomethacin or colchicine.
submitted by guy_incognito118 to gout [link] [comments]
The indomethacin was left over from my last gout attack that started 3rd week of March, and it went on for most of April, with some of the worst pain and swelling I've ever felt that started in big toe, moved to second toe and other parts of my foot, and once my foot got better my knee flared up.
I had x-ray and bloodwork done in April, confirmed high UA, got prescribed indo to help with flareup, then was told to make a follow up appointment to get on allo once that calmed down. Doc who prescribed allo and naproxen said to stop indo (which I'd already done). I don't know why naproxen with allo instead of more indomethacin or colchicine.
2024.05.11 15:31 JBear_Alpha Flare Up Frequency
I got gout when I was 28 years old, doing 2 workouts per day (full lift and a multi mile run), and not drinking enough water (my fault -- MAYBE 16 ounces per day at the time... I know) while living in a brutal tropical climate (add more dehydration). At that time, at most it popped up 1-3 times per year for several years. Now, I'm turning 35 and in the last 2 calendar years I'd be willing to say I've had flare ups at LEAST 20 times in that time. I've also recently started allopurinol (not sure if it's helping at all or just not helping enough).
Most, if not all of us, are aware of the debilitating pain. I currently have a case that has "lasted" for a week, started in the Achilles, moved to the bottom of the big toe joint, and now separately in the TOP of the big toe joint. 3 joints in a week and it's just so mentally, physically, and psychologically draining.
I can't pretend to have the BEST diet in the world but, I rarely have alcohol anymore (maybe once every few months or even less) and I try to drink a 64 oz jug of water every day. I rarely snack. If anything I forget to eat/drink more often than anything. Because of the frequency of me having taken colchicine in the past several months they refused to give me colchicine again, so I've been riding these out very painfully while continuing work. I did try an IV/Hydration drip bar with some anti-inflammatory mix and it was helping a ton within an hour, lasted about 2 days before this top toe joint started new.
I keep reading that twice is considered a LOT in a calendar year. Am I the only one getting it insanely often and nothing seems to help now? I know few people that have it and theirs isn't nearly as often.
Sometimes it will be a week then it will start again in another joint the same morning the other one stops, or like this week 2 joints at once and a third once those are better. Then I'll be fine for 1-2 months (big maybe). I know we can all do better on our collective daily intakes but it feels like I'm doing things to avoid high purine in a LOT of cases completely and it just doesn't matter.
submitted by JBear_Alpha to gout [link] [comments]
Most, if not all of us, are aware of the debilitating pain. I currently have a case that has "lasted" for a week, started in the Achilles, moved to the bottom of the big toe joint, and now separately in the TOP of the big toe joint. 3 joints in a week and it's just so mentally, physically, and psychologically draining.
I can't pretend to have the BEST diet in the world but, I rarely have alcohol anymore (maybe once every few months or even less) and I try to drink a 64 oz jug of water every day. I rarely snack. If anything I forget to eat/drink more often than anything. Because of the frequency of me having taken colchicine in the past several months they refused to give me colchicine again, so I've been riding these out very painfully while continuing work. I did try an IV/Hydration drip bar with some anti-inflammatory mix and it was helping a ton within an hour, lasted about 2 days before this top toe joint started new.
I keep reading that twice is considered a LOT in a calendar year. Am I the only one getting it insanely often and nothing seems to help now? I know few people that have it and theirs isn't nearly as often.
Sometimes it will be a week then it will start again in another joint the same morning the other one stops, or like this week 2 joints at once and a third once those are better. Then I'll be fine for 1-2 months (big maybe). I know we can all do better on our collective daily intakes but it feels like I'm doing things to avoid high purine in a LOT of cases completely and it just doesn't matter.
2024.05.10 08:48 Radweevil88 Coworkers and friends think I’m being dramatic.
I was diagnosed with gout about 3 years ago, but probably have had the condition significantly longer than that. It was a frustrating experience because Covid was in full swing, everything was shut down and it was challenging to get into to see a doctor. It didn’t help that the doctor I initially saw didn’t do a blood panel and I was too ignorant at the time to ask for one. They x-rayed my foot and I was misdiagnosed as having a hairline fracture on one of the bones in my foot and sent home and told to take ibuprofen, keep it elevated and iced. I’ve broke my foot before, and this hurt worse and different from that, and I told the doctor I didn’t remember doing anything to the foot that would cause a fracture, but ended up being sent on my way.
A week later the pain got worse and I remember my knees starting to feel stiff and sore, but I attribute that to the weird way I was walking. My mother, a nurse, insisted I go back to the clinic, ask for a different doctor, and not leave until they ordered a blood panel. I did, they quickly discovered my uric acid levels were abnormally high. I got the usual protocol of colchicine and allopurinol and after a few weeks it was improved. My allo rx at that time was temporary, but about a year ago they started me on it probably for the rest of my life. It’s not my favorite thing in the world, but it’s better than gout. It was working more or less fine until about 2 weeks ago when I had probably the worse flair up I’ve ever had. It was excruciating painful and for about 3 day I could barely walk to the bathroom. I had to drive in to see my doctor (my gout was in my right foot) because he wouldn’t prescribe another round of colchicine without seeing me in person. I was a little salty about that.
Basically, this is a very long winded way of saying it was a miserable week made more miserable because I had to go into work while the gout was in full swing. My coworkers got to see me in all my gouty glory. Now, my coworkers are good people and most of them are my friends, but all of them made joking comment about how ‘dramatic’ I was being about stubbing a toe. One of my friends made a joking comment about how wimpy men are about pain. It wasn’t malicious but, holy Moses it was annoying. I’m trying to remember that before I actually had gout I had NO clue about how debilitating it can actually is. I’m not actually dramatic person and a rarely complain about pain, but I’m not exaggerating when I say some of the worst, most intense pain I’ve experienced in my life has been from gout. I just wish when I told people that it wasn’t treated as a joke or with derision.
Okay, I’m done ranting.
submitted by Radweevil88 to gout [link] [comments]
A week later the pain got worse and I remember my knees starting to feel stiff and sore, but I attribute that to the weird way I was walking. My mother, a nurse, insisted I go back to the clinic, ask for a different doctor, and not leave until they ordered a blood panel. I did, they quickly discovered my uric acid levels were abnormally high. I got the usual protocol of colchicine and allopurinol and after a few weeks it was improved. My allo rx at that time was temporary, but about a year ago they started me on it probably for the rest of my life. It’s not my favorite thing in the world, but it’s better than gout. It was working more or less fine until about 2 weeks ago when I had probably the worse flair up I’ve ever had. It was excruciating painful and for about 3 day I could barely walk to the bathroom. I had to drive in to see my doctor (my gout was in my right foot) because he wouldn’t prescribe another round of colchicine without seeing me in person. I was a little salty about that.
Basically, this is a very long winded way of saying it was a miserable week made more miserable because I had to go into work while the gout was in full swing. My coworkers got to see me in all my gouty glory. Now, my coworkers are good people and most of them are my friends, but all of them made joking comment about how ‘dramatic’ I was being about stubbing a toe. One of my friends made a joking comment about how wimpy men are about pain. It wasn’t malicious but, holy Moses it was annoying. I’m trying to remember that before I actually had gout I had NO clue about how debilitating it can actually is. I’m not actually dramatic person and a rarely complain about pain, but I’m not exaggerating when I say some of the worst, most intense pain I’ve experienced in my life has been from gout. I just wish when I told people that it wasn’t treated as a joke or with derision.
Okay, I’m done ranting.
2024.05.10 00:06 Quietinthemorning I need help
I have a complicated issue medically where right now I'm not tolerating most foods (MCAS). I'm able to take peptide drinks for nutrition and water and that's it. Unfortunately that has led to a perpetual gout flare for months, where one will end and a couple days later (if that) another begins. I now have gout in both of my feet and it's been extremely hard to handle.
My doctor prescribed colchicine and wants me to start allopurinol once the flares calm down but I've been waiting weeks/months for that to happen. Currently I manage by taking colchicine and arthritis strength tylenol but it doesn't do enough and I don't tolerate colchicine very well for very long. I have reacted negatively to steroids and cannot take them, same for NSAIDs.
If you have any advice or insight please let me know. My uric acid was 18.2 at the hospital a couple weeks ago.
submitted by Quietinthemorning to gout [link] [comments]
My doctor prescribed colchicine and wants me to start allopurinol once the flares calm down but I've been waiting weeks/months for that to happen. Currently I manage by taking colchicine and arthritis strength tylenol but it doesn't do enough and I don't tolerate colchicine very well for very long. I have reacted negatively to steroids and cannot take them, same for NSAIDs.
If you have any advice or insight please let me know. My uric acid was 18.2 at the hospital a couple weeks ago.
2024.05.07 16:09 cmc1of3 Hiking After Starting Allopurinol?
Hey all! My backstory is similar to many - been suffering through flares of gout for years, was able to minimize flare ups for a while by controlling purine intake, but that doesn’t seem to be working like it used to. So my doctor has prescribed Allopurinol along with Colchicine for the first 4-6 months. I’m planning to start it this week.
My wife and I have a trip to Rocky Mountain National Park planned for end of June with our kids. We’re planning to do a decent amount of hiking (nothing crazy, our kids are young). So I’m questioning whether it’s smart to start the drugs now or wait until after the trip.
I know it’s a mixed bag and different people have different experiences. But for those of you who started Allopurinol along with daily Colchicine, what would you recommend? Was it manageable enough that you think I’ll be fine in this trip? Or did you have intense flare ups within the first 6 weeks?
Of course there’s a chance I get a flare up that week regardless, so it may not even matter! But wondering your experiences!
submitted by cmc1of3 to gout [link] [comments]
My wife and I have a trip to Rocky Mountain National Park planned for end of June with our kids. We’re planning to do a decent amount of hiking (nothing crazy, our kids are young). So I’m questioning whether it’s smart to start the drugs now or wait until after the trip.
I know it’s a mixed bag and different people have different experiences. But for those of you who started Allopurinol along with daily Colchicine, what would you recommend? Was it manageable enough that you think I’ll be fine in this trip? Or did you have intense flare ups within the first 6 weeks?
Of course there’s a chance I get a flare up that week regardless, so it may not even matter! But wondering your experiences!
2024.05.02 20:25 ryunken Toe and foot still not recovered
Had my first flare about 7 weeks ago which lasted about 2 weeks but subsided after some Colchicine and Prednisone however my toe and foot still hasn't fully recovered and I still get slight pains in the joint every so often.
I am taking Naproxen or Nurofen when I get these slight pains to keep a flair from happening but wondering when will my toe and foot return to normal or is this the new normal??
I've changed diet, cut out red meat and cut down on alcohol and upped water intake along with some additional supplements so trying the natural route before going on allopurinol
submitted by ryunken to gout [link] [comments]
I am taking Naproxen or Nurofen when I get these slight pains to keep a flair from happening but wondering when will my toe and foot return to normal or is this the new normal??
I've changed diet, cut out red meat and cut down on alcohol and upped water intake along with some additional supplements so trying the natural route before going on allopurinol
2024.05.02 08:34 Real_Deal_1440 Allopurinol 300mg caused my AST/ALT number to go sky high?
Is this possible? I just did a blood draw and here are my numbers
ALT: 108 AST: 51
prior to that below we're my readings the past three years ALT: 56 ,31, 44 AST: 24, 19, 24
I do know last June when I was taking 100mg Allopurinol my UA was at 7.7 so my rheumatologist upped it to 300mg, but then I was supposed to do blood work a month later but didn't until yesterday. BTW I he also has me taking colchicine daily along. with the allopurinol.
I'm surprised my Rheumatologist isn't alarmed at these numbers, my Internet searches pretty well me my numbers indicate liver damage??
submitted by Real_Deal_1440 to gout [link] [comments]
ALT: 108 AST: 51
prior to that below we're my readings the past three years ALT: 56 ,31, 44 AST: 24, 19, 24
I do know last June when I was taking 100mg Allopurinol my UA was at 7.7 so my rheumatologist upped it to 300mg, but then I was supposed to do blood work a month later but didn't until yesterday. BTW I he also has me taking colchicine daily along. with the allopurinol.
I'm surprised my Rheumatologist isn't alarmed at these numbers, my Internet searches pretty well me my numbers indicate liver damage??
2024.05.01 20:54 Proxymelon Well.. it happened again.
I got my first flare up about 3 months ago. It was really bad and I never wanted it to happen again but I decided to do it the all natural way. I stopped drinking alcohol mostly and only ate chicken for meat. This last weekend though I loosened up and ate some beef enchiladas and two beers for lunch. A day later my big toe started hurting. Today it started flaring and swelling even worse than before. I went to the doctor today and was prescribed colchicine and allopurinol. If you have gout and think you can just eat healthier I promise you're going to regret that. I'm in such pain right now at work trying to walk.
Also... How long does colchicine take to work? Will I be able to walk after a full day of being on it?
submitted by Proxymelon to gout [link] [comments]
Also... How long does colchicine take to work? Will I be able to walk after a full day of being on it?
2024.04.30 02:48 Southern_Spell6752 Gout in spine
Anyone ever have gout on the spine? Yesterday I just kicked it all day. Didn't lift anything or do anything strenuous. Today I woke up to severe lower and upper back pain. Throughout the day the lower pain went away. Now I have severe upper back pain. I can hardly move. It hurts to breathe. I'm on allopurinol and I took colchicine as soon as I noticed. I've been a gout patient for over 20 years. Been through everything except spine. Anyone else get this?
submitted by Southern_Spell6752 to gout [link] [comments]
2024.04.28 02:42 -iron_owl- Gout prescription
Just came back from the doctor after my second attack in a month. I had my first attack whilst on holiday overseas and was prescribed Colchicine and Naproxen which I took for about 4 days. Came back from the holiday almost pain-free but there was still a bit lingering so I saw a local doctor who prescribed me prednisolone (2x for the first day and 1x each day for the next 2 days)
I was completely pain free for 2 days after the meds until another full blown attack came on. I then saw a different doctor (my other doctor was not available) who prescribed me a higher and longer dose of prednisolone (2x a day for first 3 days then 1x a day for the next 3 days), to be followed by Colchicine and Allopurinol together (1x a day for 2 weeks), then Allopurinol ongoing.
Is this a typical prescription? I’m very new to gout and have not been on any type of medication before outside of OTC painkillers, but it just seemed a bit excessive after doing some reading online.
submitted by -iron_owl- to gout [link] [comments]
I was completely pain free for 2 days after the meds until another full blown attack came on. I then saw a different doctor (my other doctor was not available) who prescribed me a higher and longer dose of prednisolone (2x a day for first 3 days then 1x a day for the next 3 days), to be followed by Colchicine and Allopurinol together (1x a day for 2 weeks), then Allopurinol ongoing.
Is this a typical prescription? I’m very new to gout and have not been on any type of medication before outside of OTC painkillers, but it just seemed a bit excessive after doing some reading online.
2024.04.24 19:57 MaxInTheGameIndustry Excited To Join
Welp. It appears that I'm on the road to getting diagnosed. I've had gout for about a decade (diagnosed at 22). Only had 5-6 flare ups from 2013/2014 to 2022 - then I had several in both ankles (which was different). However, bloodwork came back normal for the majority. Was on allopurinol and colchicine until I didn't have a flare for 18 months.
Flash forward to Feb 2024, I get my gallbladder out and 3 days later I have a small flare - followed by a flare so bad in April that I went to the ER twice.
They did some blood tests and my doctor mentioned he thinks I might have RA that was misdiagnosed as gout (or, at the very least, was masked as gout).
So I'm going to a Rheumatologist on Monday to get it all checked out but my feet haven't had a moment of non pain since April 5 even with an 8 day taper of Prednisone.
Hooray.
submitted by MaxInTheGameIndustry to rheumatoid [link] [comments]
Flash forward to Feb 2024, I get my gallbladder out and 3 days later I have a small flare - followed by a flare so bad in April that I went to the ER twice.
They did some blood tests and my doctor mentioned he thinks I might have RA that was misdiagnosed as gout (or, at the very least, was masked as gout).
So I'm going to a Rheumatologist on Monday to get it all checked out but my feet haven't had a moment of non pain since April 5 even with an 8 day taper of Prednisone.
Hooray.
2024.04.19 18:05 Dad-Boner Would you participate in a gout study?
I’ve never taken allopurinol for gout, which I’ve managed for 15 years or more with colchicine when dealing with a flare up. In the past year or so the flares are happening 1-2 times a month and are usually just stiffness. Gout started in my big toe, eventually spread to my other foot (on top) and then a knee. I’m so sick of it. The other day I responded to an online survey for a gout study and got a call. I made a visit and in next week or so may join a study for non-fda approved drugs for gout. It pays but I’m beginning to have second thoughts of being a Guinea pig for big pharma. Atom Bioscience is supporting the research for drug ABP-671. The research also includes allopurinol and placebo, which there’s a 17 percent chance of receiving. The research study is a Phase 2b/3 clinical trial for the effectiveness and safety of ABP-671, which is supposed to increase the excretion of uric acid in urine by stopping the function of a type of protein in kidneys. Kidney stones are a risk. The study goes for 34 week with 17 visits, which pay $90 each. Not exactly life-changing money, I’d do it more for treatment. But I’m beginning to have second thoughts and would like to get on allopurinol and get back to a normal life. I’m in my late 40s, good shape, exercise regularly and take no medications. What would you recommend?
submitted by Dad-Boner to gout [link] [comments]
2024.04.19 16:39 basado94777 Buying prescription free gout remedies during Mexico vacation?
I (M29) had my first gout flare almost a year ago, and man, those five minutes felt like an eternity of agony. Then, just a month later, bam! Another flare hit, and this time it hung around for days. So, off to the doc I went. He checked my blood, said my uric acid levels were on the high side of normal, and handed me some naproxen. But let me tell you, that naproxen might as well be a placebo because it hasn't made a dent in my pain.
Since then, I've been on a mission. Meat? Rare treat. Water? Chugging it like it's going out of style. But still, these darn flares keep coming back. I also consulted another doctor few months ago who found no abnormal uric acid levels and didn't prescribe medication. To be fair, my gout flare subsided just few days before I went to that second doc. Right now, though, I'm in the midst of a flare, and I'm dreading my upcoming trip to Mexico.
I figure might be my fault. Been hitting the gym hard for the past few weeks, watching what I eat like a hawk, but maybe I'm overdoing it. Could be why my uric acid levels might be high at the moment but I haven't gone to the doc yet.
So, here's the deal: if this flare sticks around or gets worse during my vacay, should I hit up a Mexican pharmacy for some allopurinol or colchicine? I've heard you can get that stuff over the counter there. But I'm torn, 'cause who knows what kind of risks come with popping pills without a doc's say-so? I'll keep popping my Naproxen and Ibuprofen, even though they're not doing much.
So, what would you do in my shoes?
submitted by basado94777 to gout [link] [comments]
Since then, I've been on a mission. Meat? Rare treat. Water? Chugging it like it's going out of style. But still, these darn flares keep coming back. I also consulted another doctor few months ago who found no abnormal uric acid levels and didn't prescribe medication. To be fair, my gout flare subsided just few days before I went to that second doc. Right now, though, I'm in the midst of a flare, and I'm dreading my upcoming trip to Mexico.
I figure might be my fault. Been hitting the gym hard for the past few weeks, watching what I eat like a hawk, but maybe I'm overdoing it. Could be why my uric acid levels might be high at the moment but I haven't gone to the doc yet.
So, here's the deal: if this flare sticks around or gets worse during my vacay, should I hit up a Mexican pharmacy for some allopurinol or colchicine? I've heard you can get that stuff over the counter there. But I'm torn, 'cause who knows what kind of risks come with popping pills without a doc's say-so? I'll keep popping my Naproxen and Ibuprofen, even though they're not doing much.
So, what would you do in my shoes?
2024.04.16 17:56 KRYSTEXXA [GUIDE] Got uncontrolled gout? We hear ya. Come on in here for some gout education and a potential treatment option.
![[GUIDE] Got uncontrolled gout? We hear ya. Come on in here for some gout education and a potential treatment option.](https://b.thumbs.redditmedia.com/Mhuvye7fDZ0gYeDeJ-p-4CkdMp7W-1w0NwWdr_6ebeY.jpg "[GUIDE] Got uncontrolled gout? We hear ya. Come on in here for some gout education and a potential treatment option.") | [TL;DR] If you’ve got gout that isn’t under control, you’re probably looking high and low for answers. You’ve come to the right place! Let’s talk a bit about gout, how it works, and a treatment that could help you get back in control.What is uncontrolled gout?Before we dive into what gout even is, let’s get this answer out of the way – the bottom line is that If you’re taking oral gout meds but you still have a high uric acid level (above 6 mg/dL) and have gouty lumps or more than one flare a year, your gout may be uncontrolled. If that’s you – don’t worry! Read on. There’s hope for you yet. https://preview.redd.it/o3eqlga75vuc1.png?width=990&format=png&auto=webp&s=65eb3d215b7b1d206d7e09e323afb7c63acc4801 First of all – what is gout? To get into the nitty gritty – gout is caused by too much uric acid in the body. Too much uric acid in your blood means crystals can form in your body, causing pain and swelling in your joints and bones. Name a body part – uric acid crystals can probably form there. This can happen all over the place, really, even in your organs. Kidneys? Heart? Knee? Big toe? Yep, yep, yep and yep. What are the symptoms of gout? This is the annoying part – the main symptom of gout is a sudden attack of severe pain, called a flare. You might see redness and swelling in your joints, and you may also feel heat in those areas. The big toe is the classic target, but gout can also affect the ankle, knee, insteps, heels, wrists, fingers, ribcage, spine and elbows. https://preview.redd.it/c4xtjsu9b1wc1.png?width=2046&format=png&auto=webp&s=3f9fce163fcd8b491ec6b1947542b3685ae2a1fa Another thing to look out for are tophi – these are deposits of uric acid crystals that may look like lumps under the skin. When there is too much uric acid, it can crystallize into solid form and become tophi, causing pain and swelling. Tophi may be plainly visible, but there is often more going on under the surface that you can’t see! So if you can see them, chances are you have some other buildup elsewhere that you can’t see. The above image of a hand on the right shows the tophi you can see, and the X-ray image on the left shows the additional non-visible uric acid buildup (green areas). Anything else I need to know about gout? Sure! Plenty. For one – gout is more common in men than in women. But regardless of gender, the chance of gout increases with age. Genetics play a role, too – if your parents had issues with gout, you could too. https://preview.redd.it/mix9t8eb5vuc1.png?width=994&format=png&auto=webp&s=a8d56e67dcf3f78d08b6d2061904dff55116bd6d A big takeaway here is that the more gout builds up, the more harm it can do. So when you make it through a flare and think “Phew! Glad that’s over” – don’t get too comfy. Uric acid buildup can permanently damage your joints and bones. That's why it’s so important to get it under control! Let’s bust some myths about gout! MYTH: Diet is to blame for chronic gout
How do I know if my gout is uncontrolled? We’ve got a handy little quiz for you here.
Here's how it's treated You may be familiar with the oral options for gout medications. There are urate-lowering medicines like Allopurinol, Febuxostat, and Probenecid, that are intended to lower your serum uric acid level (or sUA). And there are other medicines that may be prescribed to take specifically during a flare to help with pain or inflammation: steroids, Colchicine, or NSAIDs (non-steroidal anti-inflammatory drugs). But the fact of the matter is that these oral meds might not be doing enough. Oral meds could have a hard time reducing your uric acid and getting rid of gout buildup, which means you may still experience gout flares. Not ideal! https://preview.redd.it/d7f3629h5vuc1.png?width=1002&format=png&auto=webp&s=4b0fbcc3c5f9df1049742d072502968aba5d7380 If oral meds aren't helping, KRYSTEXXA® (pegloticase) might For those who are taking oral gout medicines and are still experiencing multiple flares a year or tophi, KRYSTEXXA has been shown to reduce uric acid levels. KRYSTEXXA is a prescription medicine used in adults to help reduce the signs and symptoms of gout that are not controlled by other treatments. KRYSTEXXA is not for use in people with too much uric acid in their bodies who do not have symptoms (asymptomatic hyperuricemia). What is the most important information I should know about KRYSTEXXA® (pegloticase)? Serious allergic reactions may happen in some patients who receive KRYSTEXXA. These allergic reactions can be life-threatening and usually happen within 2 hours of the infusion. KRYSTEXXA should be given to you by a doctor or nurse in a healthcare setting where serious allergic reactions can be treated. Your doctor or nurse should watch you for any signs of a serious allergic reaction during and after your treatment with KRYSTEXXA. Please see additional Important Safety Information at the bottom of this page. Please see Medication Guide at KRYSTEXXA.com Here’s how it works – instead of treating the symptoms of gout, KRYSTEXXA goes after the underlying cause. Oral meds attempt to lower uric acid levels, while KRYSTEXXA works to change uric acid into a water-soluble substance called allantoin that your body easily gets rid of through urine. This means that with KRYSTEXXA, you can start to significantly lower your uric acid level in just 24 hours. Think of it this way – it can take more than 2 years for oral meds to dissolve even a small amount of uric acid crystal buildup. KRYSTEXXA can dissolve most of it in 6 to 12 months.* Your doctor may prescribe a medication called methotrexate to be taken while you’re on KRYSTEXXA treatment. Patients who used KRYSTEXXA along with methotrexate had fewer infusion reactions and more reductions in tophi, or gouty lumps, than patients who used KRYSTEXXA alone. If your doctor doesn’t think methotrexate is right for you, KRYSTEXXA is also effective on its own. *Optimal treatment duration has not been established. What are the possible side effects of KRYSTEXXA? In KRYSTEXXA clinical trials: The most common side effects of KRYSTEXXA when given together with methotrexate were gout flares, joint pain, coronavirus disease 2019 (COVID-19), nausea, and fatigue. The most common side effects of KRYSTEXXA were gout flares, allergic reactions (including infusion reactions). See “What is the most important information I should know about KRYSTEXXA?”, nausea, bruising, sore throat, constipation, chest pain, coronavirus disease 2019 (COVID-19), and vomiting. This is not a complete list of all possible side effects. Call your doctor for medical advice about side effects. Please see additional Important Safety Information at the bottom of this page. Please see Medication Guide at KRYSTEXXA.com https://preview.redd.it/jfwyqsgcb1wc1.png?width=1838&format=png&auto=webp&s=c82ff886dd6c14df002d4777e47f61a058e3de4c Best results were seen in 6-12 months. Optimal treatment duration has not been established. Individual results may vary. So – what next? We’ve got some handy dandy resources for you to take advantage of, and in the meantime, find yourself a gout specialist (usually a rheumatologist or nephrologist) who understands uncontrolled gout and treatment with KRYSTEXXA.
If you’re on oral gout meds and it still feels out of your control – talk to a gout specialist about KRYSTEXXA. USE AND IMPORTANT SAFETY INFORMATION What is the most important information I should know about KRYSTEXXA® (pegloticase)? Serious allergic reactions may happen in some patients who receive KRYSTEXXA. These allergic reactions can be life-threatening and usually happen within 2 hours of the infusion. KRYSTEXXA should be given to you by a doctor or nurse in a healthcare setting where serious allergic reactions can be treated. Your doctor or nurse should watch you for any signs of a serious allergic reaction during and after your treatment with KRYSTEXXA. Tell your doctor or nurse right away if you have any of these symptoms during or after your treatment with KRYSTEXXA:
Do not receive KRYSTEXXA if you:
Before you receive KRYSTEXXA, tell your doctor about all of your medical conditions, including if you:
KRYSTEXXA is recommended to be given with another prescription medicine called methotrexate. KRYSTEXXA may also be used alone. You and your doctor will decide the treatment that is right for you. Prior to your treatment with KRYSTEXXA, your doctor may give you medicine to help reduce your risk of getting gout flares or an allergic reaction. Take these medicines as directed by your doctor or nurse. Your doctor will also test your uric acid levels prior to each treatment to monitor your response to KRYSTEXXA. Your gout flares may increase in the first 3 months when you start receiving KRYSTEXXA. It’s important to understand that this is happening because KRYSTEXXA is breaking down uric acid in your body. Do not stop receiving KRYSTEXXA even if you have a flare, as the amount of flares will decrease after 3 months of treatment. Your doctor may give you other medicines to help reduce your gout flares for the first few months after starting KRYSTEXXA. What are the possible side effects of KRYSTEXXA? In KRYSTEXXA clinical trials: The most common side effects of KRYSTEXXA when given together with methotrexate were gout flares, joint pain, coronavirus disease 2019 (COVID-19), nausea, and fatigue. The most common side effects of KRYSTEXXA were gout flares, allergic reactions (including infusion reactions). See “What is the most important information I should know about KRYSTEXXA?”, nausea, bruising, sore throat, constipation, chest pain, coronavirus disease 2019 (COVID-19), and vomiting. This is not a complete list of all possible side effects. Call your doctor for medical advice about side effects. You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/safety/medwatch or call 1-800-FDA-1088. For additional Important Safety Information, please see the Medication Guide and discuss with your doctor. USE KRYSTEXXA is a prescription medicine used in adults to help reduce the signs and symptoms of gout that are not controlled by other treatments. KRYSTEXXA is not for use in people with too much uric acid in their bodies who do not have symptoms (asymptomatic hyperuricemia). ©2024 Amgen Inc. All rights reserved. P-KRY-US-01288 05/24 |
2024.04.14 12:19 pretty_inink Getting worried about my husband on colchicine
Edit: Update! He was taken off colchine after a week as it was making him feel unwell. He is now on low dose Allopurniol.
Hi, my husband has recently been prescribed colchicine 500 micrograms twice a day for at least 6 weeks to control his flare ups and he will be starting Allopurinol after 3 weeks of colchicine.
Now I do overly worry, but it's only been a week and the past 2 days he's been complaining of dizziness. He also is dealing with digestive issues but I was told that's normal? Ive read the leaflet and it's just made me panic.
I swear I read somewhere that you should be drinking a certain amount of water to prevent the dizziness and other side affects of colchicine, is that true?? He hasn't been drinking much lately.
I am absolutely consumed by worry and just need some general advice. Should I be contacting his doctor or am I just being over dramatic?
submitted by pretty_inink to gout [link] [comments]
Hi, my husband has recently been prescribed colchicine 500 micrograms twice a day for at least 6 weeks to control his flare ups and he will be starting Allopurinol after 3 weeks of colchicine.
Now I do overly worry, but it's only been a week and the past 2 days he's been complaining of dizziness. He also is dealing with digestive issues but I was told that's normal? Ive read the leaflet and it's just made me panic.
I swear I read somewhere that you should be drinking a certain amount of water to prevent the dizziness and other side affects of colchicine, is that true?? He hasn't been drinking much lately.
I am absolutely consumed by worry and just need some general advice. Should I be contacting his doctor or am I just being over dramatic?
2024.04.14 05:13 Cali__1970 After the flare - questions
So I believe I had my first big foot flare 7 (!!) weeks ago.
Went to ER on Feb25 and after antibiotics for misdiagnosed cellulitis went on methylprednisolone March 15 to reduce inflammation. Flared up again and Gout expected. April 5 did a 5 day colchicine that brought down the pain and most of the swelling.
Docs here do not want to prescribe allopurinol until at least 3 attacks. I have been avoiding all red meat and added sugars but fully understand that diet alone is usually not enough.
Today I’m still dealing with toe pain. Especially later in the day when I have walked quite a bit (I have kids that need to be brought to school, cooked for, entertained etc). It’s minor and nowhere close to what it was late February.
Q1: is this pain normal so long after the hight of the flare up? (Now roughly 7 weeks later).
Q2: if a long bout of (reduced) pain/swelling is not unheard of does this slowly but surely ebb away completely?
Q3: do flare ups follow each other relatively I. Short order? Can you have a new flare up say 2-3 months after a prior one?
submitted by Cali__1970 to gout [link] [comments]
Went to ER on Feb25 and after antibiotics for misdiagnosed cellulitis went on methylprednisolone March 15 to reduce inflammation. Flared up again and Gout expected. April 5 did a 5 day colchicine that brought down the pain and most of the swelling.
Docs here do not want to prescribe allopurinol until at least 3 attacks. I have been avoiding all red meat and added sugars but fully understand that diet alone is usually not enough.
Today I’m still dealing with toe pain. Especially later in the day when I have walked quite a bit (I have kids that need to be brought to school, cooked for, entertained etc). It’s minor and nowhere close to what it was late February.
Q1: is this pain normal so long after the hight of the flare up? (Now roughly 7 weeks later).
Q2: if a long bout of (reduced) pain/swelling is not unheard of does this slowly but surely ebb away completely?
Q3: do flare ups follow each other relatively I. Short order? Can you have a new flare up say 2-3 months after a prior one?
2024.04.11 19:43 LanStan9833 Moving the Right Direction
Howdy Sufferers,
In January I thought I tore every ligament in my knee, only to eventually find out that I was having a gout attack. Had my UA tested and came back at a 10. Talked to my PCP who prescribed me 100mg of allopurinol, which I took daily until early March. After seeing so many stories on this sub, I decided to schedule an appointment with a rheumatologist to try and get ahead of this disease. The rheumatologist immediately bumped me up to 150mg (with colchicine daily) to take for about another month and ordered labs for my UA to be checked again. Just received the lab report that shows my UA is now at 6.4, which is so close to the desired range.
I'm a 30yo male, so being immobile and essentially bed-ridden for what felt like a month was debilitating. I enjoy working out, playing sports, and especially spending time with my family. It is great to see a little glimmer of hope through all of this. I have a follow-up next week to see if an increased dosage of allo is needed. Thanks to this sub for all of the knowledge of gout and how to enjoy like through the diagnosis! Cheers.
submitted by LanStan9833 to gout [link] [comments]
In January I thought I tore every ligament in my knee, only to eventually find out that I was having a gout attack. Had my UA tested and came back at a 10. Talked to my PCP who prescribed me 100mg of allopurinol, which I took daily until early March. After seeing so many stories on this sub, I decided to schedule an appointment with a rheumatologist to try and get ahead of this disease. The rheumatologist immediately bumped me up to 150mg (with colchicine daily) to take for about another month and ordered labs for my UA to be checked again. Just received the lab report that shows my UA is now at 6.4, which is so close to the desired range.
I'm a 30yo male, so being immobile and essentially bed-ridden for what felt like a month was debilitating. I enjoy working out, playing sports, and especially spending time with my family. It is great to see a little glimmer of hope through all of this. I have a follow-up next week to see if an increased dosage of allo is needed. Thanks to this sub for all of the knowledge of gout and how to enjoy like through the diagnosis! Cheers.
2024.04.09 07:43 S3LY I made a mistake..
Hi everyone, I'm new here and unfortunately dealing with a nasty gout attack in both feet right now. It's been going on for about a week, with the pain recently shifting to my right big toe and easing up in the left. I'm currently on 300mg of allopurinol daily and just started a 9-day course of colchicine.
I definitely take responsibility for this flare-up. I forgot how much frozen dinners, soda, red bull, and beer can trigger attacks. Lesson learned! Big time!
submitted by S3LY to gout [link] [comments]
I definitely take responsibility for this flare-up. I forgot how much frozen dinners, soda, red bull, and beer can trigger attacks. Lesson learned! Big time!