Lamictal sde effects

I was given meds last week

2024.05.14 18:19 CalendarHot3878 I was given meds last week

I am on 25 lamictal a day for a few more days until I have to start increasing my dose. I’ve never taken any prescribed medications before I didn’t even know how to get my prescription and I was getting unsettled by the whole thing. I have a mood chart I have to log my mood every day. From what I can tell I was stable when I had my appointment last week and I feel calmer most of the time now but I still have compulsive anxiety sometimes but usually my confidence fluctuates a lot and that’s not happening so much.
I keep thinking this is a placebo effect. I think two of my coworkers told me I seem less stressed. I feel like maybe my life will be way better now and I feel positive. I have noticed that a lot of my delusions come from thinking obsessively so I just try and stop thinking and instead live in the moment and it’s actually very easy to decipher which thought is going to turn into a delusion because they are always intrusive thoughts.
I remember some of the things I have done in the past two years before I began being treated and instead of feeling guilt or shame I feel more understanding for myself and the burden has lifted a bit knowing that it wasn’t my fault that I acted that way I was unwell.
submitted by CalendarHot3878 to bipolar [link] [comments]


2024.05.14 06:53 Cag_ada My review of lamictal during my first week of taking it- a positive review.

Im sure I have felt like a lot of you on this sub.
Suffering, frightened, skeptical. There’s no better words to express the way I felt, at least.
Anti-depressants? Tried them. Life style changes? I did my best. Therapy? I’m this close to calling my therapist my “bestie” at this point. Jokes aside, I came across this drug. I used to think “Nah, that’s not for me” or whatever other rationalizing BS. Denial.
My world was shrouded in the darkest veil that clouded my vision. Anhedonia. Despair. Loneliness, even in a room full of people who love me. Rumination. Racing thoughts. Hopelessness. ANXIETY. That word alone has become my middle name…Panic. Fear. Inability to relax. Muscle tension. Unable to even enjoy the beauty in front of me because I was sitting in the abyss with this veil choking me, forcing its way down into my lungs.
Anyway- enough of the very real dramatization.
It is day 7 on 25mg of lamictal.
For the first time, in a very long time…I feel like me. Rumination? Minor. Sadness? Here and there- but with a pep in my step. Anxiety? Oh, that old friend? Sure, maybe, but nothing a propranolol couldn’t handle- considering I had to take so much lorazepam to simply function like the society-contributing “normal” human being, not someone choking to death on their own misery.
Thoughts: calm. Mind: focused. Vision: Clear. Heart: Less heavy. Chest: less tight.
It’s like the veil has finally lifted; it feels like I woke up from the blackest nightmare.
I had the worst year of my life last year. I got very sick, then got assaulted by my ex-partner, terrorized by him before the law and courts got involved, then my loving father was put into hospice. I didn’t think I was even going to make it.
And just two nights ago- the flood gates opened, and I sobbed for literally two hours on my partners chest- finally feeling the grief of my father passing soon. A festering infection that just stayed in my chest, the deepest pain, my eyes could not stop streaming. Because for the first time, in a long time- I don’t feel painfully numb.
I feel like a human being.
Tomorrow, I up the dose to 50mg. I’m nervous, but curious. I feel such a difference at 25mg- minimal side effects. Some dry skin, minor itchiness of the face, a nice Benadryl before bed takes care of it.
I’m still cautious of all of these potential side effects. I’m wary-
But.
For the first time, ever- I feel hope.
And I can finally feel joy playing with my precious dog that has gotten me through the darkest of times. I can show up for her, my parents, my loving partner, and….myself.
I love you all. Thank you to every member of this sub. Each one of your posts helps so many of us out here.
Taking lamictal for PMDD, MDD, panic disorder, GAD, and C-PTSD.
submitted by Cag_ada to lamictal [link] [comments]


2024.05.14 03:45 Sendpiecks does lamictal make it more difficult for you to be in hot weather and/or do rigorous activity outside?

hi, i’m 2 days on lamictal. so far, the only uncomfortable physical side effects are i sweat a little bit more than usual, i get a little dizzy after moving around, and i’m a bit more sensitive to bright lights. my dosage is 25mg but i’m sure my psychiatrist intends on increasing it.
i plan on working as a camp counselor this summer, but i worry that this medicine will make that more difficult for me to do. i’m just concerned and want to see some opinions, and/or some advice on how to take better care of myself better during the heat if it is an issue.
submitted by Sendpiecks to lamictal [link] [comments]


2024.05.13 22:49 sex1rat2 Anything good

So I’m about to start taking Abilify and so far on reddit i’ve seen very few positive things that are to be said about this medication. I’m very scared to start taking it now due to what i’ve seen on here as well as reading the side effects. I am currently on lamictal and it’s definetly helped steady my mood swings. Now i just feel suicidal everyday and have to fight myself from self harming. I’m tired of feeling this way and with do almost anything to make it stop.
But I am horrified to start this medication for fear it will make everything worse or make me feel nothing at all. Is there anything positive to be said about this medication and how it improved peoples lives?
submitted by sex1rat2 to Abilify_Aripiprazole [link] [comments]


2024.05.13 21:55 polarbi222 2nd Round

BP2 - Was on Lamictal 2 years ago, didn’t do well past 25mg, so i got off it (psych advised). I didn’t get a rash or have any bad side effects on 25mg. Fast forward to now, i have a new psych now and they want me to go back on lamictal and stay at 25mg to see if it’ll help with dissociation/depressive episodes since my lexapro only helps with anxiety/OCD.
If i didn’t get the rash the first time, will i still be good now taking it the second time? Wondering what 2nd time users have experienced when starting lamictal again. Thanks!
submitted by polarbi222 to lamictal [link] [comments]


2024.05.13 16:30 Admirable_Pop_9024 What's your go to treatment plan for mixed states? Is this a mixed state rather than unipolar depression?

A new patient(F45) mildly obese was brought in who was planned for ECT in a week. Though she might actually be bipolar (atleast on the spectrum). She was terrified of ECT.
She had severe depression including suicidality and severe agitation.
She was on Lithium 600mg/day (Started recently), Lamotrigine 200mg, Lexapro 20mg and clonazepam 1mg with quietiapine 50mg for sleep.
Since 2023 she'd been experiencing strange episodes according to her family.
Here's all the history and symptoms provided about these episodes since 2023 :
After her lexapro was increased to 20MG her symptoms have been just worsening and worsening including suicidality.
Benzos would do nothing even injectable ones for the agitation.
Then today when she came to me during the severe agitation I immediately thought of a mixed state. Gave her zyprexa and asked to taper down the lexapro.
After she took the zyprexa (sublingual) in about 2 hours experienced tremendous relief - felt calm, brain went silent and took a long nap quite refreshing. She wasn't bothered by people talking. She wasn't irritated. She just felt normal. The relief seemed never-ending.
It makes sense now how being put on lamictal back in 2023 put her into remission and it kept masking Lexapro's rebound effect(in bipolar)
I'm honestly unsure why high dose Lexapro was continued over a year (even though there was a clear worsening of symptoms with dosage increase) and why high dose benzodiazepines were constantly being used to control the agitation despite having little to no effect. Even effexor was started in cross-titration with Lexapro which further worsened her suicidality etc?
Sorta leaning towards ECT and later on adjusting the medications because it does seem to be severe and ECT it is quite effective though the patient wants to try the no-ssri approach.
If we do go with the latter approach, I plan on : - Switch to Vraylar for its good evidence in mixed states. Cariprazine is dirt cheap here.
Perhaps the increased energy from the (hypo)mania and the activation from the SSRI is resulting in the restlessness which explains the relief from Olanzapine. I've seen many hypomanic patients who'd get so restless that they wanted to crawl out of their own skin.
What's your go to treatment for mixed states? What about the efficacy of Lithium in mixed bipolarity? Which mood stabilizers seem to work best?
submitted by Admirable_Pop_9024 to Psychiatry [link] [comments]


2024.05.13 16:19 Admirable_Pop_9024 Is this a mixed state rather than unipolar depression? What's your go to treatment for mixed states?

A new patient was brought in who was planned for ECT in a week. Though she might actually be bipolar (atleast on the spectrum). She was terrified of ECT.
She had severe depression including suicidality and severe agitation.
She was on Lithium 600mg/day (Started recently), Lamotrigine 200mg, Lexapro 20mg and clonazepam 1mg with quietiapine 50mg for sleep.
Since 2023 she'd been experiencing strange episodes according to her family.
Here's all the history and symptoms provided about these episodes since 2023 :
After her lexapro was increased to 20MG her symptoms have been just worsening and worsening including suicidality.
Benzos would do nothing even injectable ones for the agitation.
Then today when she came to me during the severe agitation I immediately thought of a mixed state. Gave her zyprexa and asked to taper down the lexapro.
After she took the zyprexa (sublingual) experienced tremendous relief - felt calm, brain went silent and took a long nap quite refreshing. She wasn't bothered by people talking. She wasn't irritated. She just felt normal. The relief was long lasting.
It makes sense now how being put on lamictal back in 2023 put her into remission and it kept masking Lexapro's rebound effect(in bipolar)
I'm honestly unsure why high dose Lexapro was continued over a year and why high dose benzodiazepines were being used to control the agitation despite having little to no effect.
Sorta leaning towards ECT and later on adjusting the medications because it does seem to be severe and ECT it is quite effective though the patient wants to try the no-ssri approach.
If we do go with the latter approach, I plan on : - Using either VraylaLatuda for their good results in mixed states. Cariprazine is dirt cheap here.
What's your go to treatment plan for mixed states? Is this a mixed state rather than unipolar depression?
A new patient was brought in who was planned for ECT in a week. Though she might actually be bipolar (atleast on the spectrum). She was terrified of ECT.
She had severe depression including suicidality and severe agitation.
She was on Lithium 600mg/day (Started recently), Lamotrigine 200mg, Lexapro 20mg and clonazepam 1mg with quietiapine 50mg for sleep.
Since 2023 she'd been experiencing strange episodes according to her family.
Here's all the history and symptoms provided about these episodes since 2023 :
After her lexapro was increased to 20MG her symptoms have been just worsening and worsening including suicidality.
Benzos would do nothing even injectable ones for the agitation.
Then today when she came to me during the severe agitation I immediately thought of a mixed state. Gave her zyprexa and asked to taper down the lexapro.
After she took the zyprexa (sublingual) in about 2 hours experienced tremendous relief - felt calm, brain went silent and took a long nap quite refreshing. She wasn't bothered by people talking. She wasn't irritated. She just felt normal. The relief seemed never-ending.
It makes sense now how being put on lamictal back in 2023 put her into remission and it kept masking Lexapro's rebound effect(in bipolar)
I'm honestly unsure why high dose Lexapro was continued over a year and why high dose benzodiazepines were constantly being used to control the agitation despite having little to no effect. Even effexor was started in cross-titration with Lexapro which further worsened her suicidality etc?
Sorta leaning towards ECT and later on adjusting the medications because it does seem to be severe and ECT it is quite effective though the patient wants to try the no-ssri approach.
If we do go with the latter approach, I plan on : - Switch to Vraylar for its good evidence in mixed states. Cariprazine is dirt cheap here.
What's your go to treatment for mixed states? What about the efficacy of Lithium in mixed bipolarity? Which mood stabilizers seem to work best?
submitted by Admirable_Pop_9024 to FamilyMedicine [link] [comments]


2024.05.13 13:35 Lawliet_Yagam1 How do I make my graph look like his?

How do I make my graph look like his?
I can’t get the big spikes, I can only get really small spikes that are too thin :/
submitted by Lawliet_Yagam1 to AfterEffects [link] [comments]


2024.05.13 12:30 No_Camp_7 Lamotragine losing effectiveness and catamenial epilepsy

Has anyone experienced Lamictal not working so well after a few months?
I read that catamenial epilepsy (I have catamenial TLE) is a dominant type of drug resistant epilepsy (30% of those with drug resistant epilepsy have this type of epilepsy), and that focal temporal lobe seizures are risk factors too.
I also read that adjusting very quickly to side effects is a sign that you will build a tolerance over time. This happened to me and I was extremely pleased with how quickly my body adjusted, though it seems like it may be a case of “you can’t have your cake and eat it”.
I’m a month into having seizures again and my mood has tanked, affecting relationships and work again.
submitted by No_Camp_7 to Epilepsy [link] [comments]


2024.05.13 07:09 likky_wetpretzel How long does it take to work?

I've been on lamictal for almost 7 weeks now (100mg but started at 25. Have been on 100 for 2.5 weeks) I've been diagnosed with bipolar 2 since I started.
I just don't know if I feel different? Maybe it's because I was just at school (extremely stressful) but the past few weeks I've had depressive and manic episodes. Ik it's supposed to lessen episodes but I don't really feel like it's doing much? In my manic episode I relapsed with self harm, and I did some other dangerous stuff. My depressive episode was as they usually are- no motivation, crying, numbness, intrusive anxious thoughts, etc... every time I think it's working I have another episode
Online it says about 6 weeks but I'm tired of waiting. Ik it also won't "fix me" but I was hoping for a more noticeable effect by now. I've talked to people who said they felt better in a few weeks, but also people who said it took them months to have really noticeable effects.
How long did it take for you guys/ what should I be looking for? I'm worried it just won't work
submitted by likky_wetpretzel to lamictal [link] [comments]


2024.05.13 05:56 breezeman44 Horrible visual effect - Faulty Quest 3?

Horrible visual effect - Faulty Quest 3?
I upgraded from a HP Reverb G2 to Quest 3 the other day and I've noticed this awful texture overlay that seems to be on just about everything. I've never seen anything like it through my G2 but this effect makes everything look horrible. I've heard of SDE and MURA, is either of those what I'm seeing here? The effect is most pronounced on the white desk surfaces under the big contractor's screen, and on the yellow walls and it also makes absolutely everything at a reasonable distance from me look like it's *shimmering* which is quite awful when all objects in your entire view are doing it. This also persists across all games and even the virtual environments within the Quest 3 standalone.
Is this actually normal for the Quest 3 or have I ended up with a faulty headset? It's really difficult to play games and be immersed like this.
The effect persists regardless of which settings I use - I'm using the Airlink with a dedicated WiFi6 router with full LOS sitting only 2-3 meters away on an 80Mhz band with 1200gbps confirmed by WiFi Analyzer. I have a tried upping the render resolution to 1.5% in the Quest Link app and also up to 200% in SteamVR settings (and tried SteamLink instead with same results) and I've tried changing the bitrate and switched between 72/90/120hz with no change. I'm running it on a PC with a 3070Ti that had no issues rendering everything in amazing graphical quality with my G2, so this is really shocking.
https://preview.redd.it/x37ktegw940d1.png?width=2521&format=png&auto=webp&s=f10d43d7ab428b332b52b9218a8df370b86a562d
submitted by breezeman44 to OculusQuest [link] [comments]


2024.05.13 05:55 breezeman44 Horrible visual effect - Faulty Quest 3?

Horrible visual effect - Faulty Quest 3?
I upgraded from a HP Reverb G2 to Quest 3 the other day and I've noticed this awful texture overlay that seems to be on just about everything. I've never seen anything like it through my G2 but this effect makes everything look horrible. I've heard of SDE and MURA, is either of those what I'm seeing here? The effect is most pronounced on the white desk surfaces under the big contractor's screen, and on the yellow walls and it also makes absolutely everything at a reasonable distance from me look like it's *shimmering* which is quite awful when all objects in your entire view are doing it. This also persists across all games and even the virtual environments within the Quest 3 standalone.
Is this actually normal for the Quest 3 or have I ended up with a faulty headset? It's really difficult to play games and be immersed like this.
The effect persists regardless of which settings I use - I'm using the Airlink with a dedicated WiFi6 router with full LOS sitting only 2-3 meters away on an 80Mhz band with 1200gbps confirmed by WiFi Analyzer. I have a tried upping the render resolution to 1.5% in the Quest Link app and also up to 200% in SteamVR settings (and tried SteamLink instead with same results) and I've tried changing the bitrate and switched between 72/90/120hz with no change. I'm running it on a PC with a 3070Ti that had no issues rendering everything in amazing graphical quality with my G2, so this is really shocking.
https://preview.redd.it/qica7bhz940d1.png?width=2521&format=png&auto=webp&s=27759a90c98fe00a0dfd1523785b3e5f0409e1cb
submitted by breezeman44 to oculus [link] [comments]


2024.05.13 05:40 breezeman44 Horrible visual effect - faulty headset?

Horrible visual effect - faulty headset?
I upgraded from a HP Reverb G2 to Quest 3 the other day and I've noticed this awful texture overlay that seems to be on just about everything. I've never seen anything like it through my G2 but this effect makes everything look horrible. I've heard of SDE and MURA, is either of those what I'm seeing here? The effect is most pronounced on the white desk surfaces under the big contractor's screen, and on the yellow walls and it also makes absolutely everything at a reasonable distance from me look like it's *shimmering* which is quite awful when all objects in your entire view are doing it. This also persists across all games and even the virtual environments within the Quest 3 standalone.
Is this actually normal for the Quest 3 or have I ended up with a faulty headset? It's really difficult to play games and be immersed like this.
The effect persists regardless of which settings I use - I'm using the Airlink with a dedicated WiFi6 router with full LOS sitting only 2-3 meters away on an 80Mhz band with 1200gbps confirmed by WiFi Analyzer. I have a tried upping the render resolution to 1.5% in the Quest Link app and also up to 200% in SteamVR settings (and tried SteamLink instead with same results) and I've tried changing the bitrate and switched between 72/90/120hz with no change. I'm running it on a PC with a 3070Ti that had no issues rendering everything in amazing graphical quality with my G2, so this is really shocking.
https://preview.redd.it/0sgo63cs740d1.png?width=2521&format=png&auto=webp&s=434cdcd063f9afea728227e3df65fb81f532b5ba
submitted by breezeman44 to Quest3 [link] [comments]


2024.05.13 02:55 Master_Toe5998 Whats the next step?

TL;DR I've tried alot of meds already and nothing helped. Looking for advice or recommendations.
I'm on effexor 75mg xr in the morning. Clonidine 3x a day (it does nothing, more of a placebo) and was on mirtazipine 15mg but had to quit because it was making me wig out in my sleep. Like jerking my head side to side. And setting up in my sleep and starring forward. It also give me real bad RLS
So I've tried mirtazapine, Hydroxyzine, olanzapine, risperdone, sertraline, propranolol and a few others i dont remember right off.
My sister give ne a couple trazodone so Im going to try one tonight and see how that does me. I go to the psych Tuesday. I been thinking about asking her for wellbutrin to go with my effexor and see how she feels about nurotin/gabapentin 3x a day. She is against all controls though so probably label me as drug seeking. So anyone have any ideas as what else i could try? I been looking at lamictal, abilify, and a few others but would like some personal experiences with meds that didn't cause alot of side effects.
submitted by Master_Toe5998 to panicdisorder [link] [comments]


2024.05.13 00:41 Sendpiecks day 1 of lamictal has been fucking magical…

hey everybody, i (F20) was recently diagnosed with bp2. not sure if that’s an accurate diagnosis, but i definitely have a mood problem. skip to the 4th paragraph where i talk about my first day on lamictal, but i wanted to provide some context below about how i was doing before today.
i was taking effexor before this med, which my psych believes triggered a manic episode (it also gave me serotonin syndrome lol). i haven’t been able to get more than 3 hours of sleep per night for 2-3 weeks, haven’t really needed the sleep, my racing thoughts were uncontrollable and rampant, and i’ve been so unbelievably irritable.
i was actually considering going to inpatient two days ago, because my irritability has become pretty dangerous and my mental health was just really fucking bad. like i was in such a dark place. i’m just super impulsive, and i was one inconvenience away from doing something stupid and reckless to myself.
today i took my first dose of lamictal. it’s my first mood stabilizer. and holy fuck, i wasn’t expecting it to work right away (or at all) because my psych told me it takes 2 weeks for it to take effect, but i’m so much fucking better. it’s insane how ok i feel now.
my irritability is still there, but it’s actually managable now. i’m happy. hopeful. tolerant of people. i feel present. stable, which is so weird (and a little scary lol) because i haven’t felt stable for half of my life. my racing thoughts, which were super unbearable before, have completely stopped.
there really isn’t any bad side effects yet, other than feeling a little drowsy. but i can’t fucking believe this. i went from having little to no hope that things will get better two days ago, to applying to jobs, thinking about the future, and actually reaching out to friends and talking to them (i’ve been completely withdrawn for 8 months).
idk, it’s only the first day so i’m definitely worried that this is only an initial good reaction and that i will start to feel like shit again, but i’m feeling really hopeful otherwise. i’m feeling like myself again, and the best i’ve felt in literal years. i could cry, life doesn’t feel bleak and hopeless anymore. cheers y’all 🌚
submitted by Sendpiecks to lamictal [link] [comments]


2024.05.12 22:19 ASTRIDYA0 bipolar with eating disorder

Hey, are there any of you who have ED together with bipolar? I'am suffering from an ED since my childhood. About 20 years now. For a long time I had bulimia and I still have body dysmorphia. Three weeks ago, at the age of 26, I was diagnosed with bipolar type 2. Lamictal and Xanax are now part of my everyday life, but since I started taking the tablets I have lost a lot of appetite, which has a positive effect on me as someone who suffers from ED. But I am also aware that eating so little is not entirely healthy. And because of hypomania, I move around a lot and do more sport than normal. I burn a lot of calories... How do you guys cope with it? Would be happy about recommendations.
submitted by ASTRIDYA0 to bipolar [link] [comments]


2024.05.12 19:00 Ok-Vacation5730 Creative upscaling all the way to 16K (and beyond) with WebUI Forge, a comprehensive how-to guide

Creative upscaling all the way to 16K (and beyond) with WebUI Forge, a comprehensive how-to guide
WebUI Forge is a popular alternative (‘fork’) to the classical Automatic1111 platform. In this guide, I describe a complete routine for super high-resolution upscaling of AI-generated images with incremental adding of detail into their content, using any of the two features of Forge, SD Upscale and MultiDiffusion integrated.
Due to reddit limitations, the included 16:9 demo image of a fantasy landscape is a scaled down to 8K version of the full-size upscaled image produced with this routine from an original 2K picture generated with Leonardo.ai. Here’s the link to the full-size 15360x8640 image (a 58 MB file).
A lighter image of 16 MB size (87% jpeg compression) is available here.
The source 2k image is included second in this posting.
The folder with the complete selection of demo images from the project prepared for this post is available here.
Routine prerequisites: Forge webUI running locally on a PC equipped with a capable GPU (RTX 4070 Ti Super with 16 GB, in my setup), or on a leased one in the cloud (RunDiffusiion, salad, runpod.io, vast.ai, sailflow.ai and the like). The author used the WebUI Forge version available within the StabilityMatrix package.
The approach
In the image upscaling business, the temptation is to upscale the image to the target resolution in one go, if possible: if the tool supports a 4x upscale, sure, let’s use that! 8x, even better! It is however a very flawed approach, all you will get is a ruined image (or at best something far from what you wanted the result to be), and running times much longer than they should be. With this routine, I promote an incremental approach, where you increase the resolution 2 times at most with each upscale step, keeping the runtimes short to allow for more creative experimenting. The underlying idea is that you want to be in charge of the process and not rely on the magic of the AI too much, or on some dense, rigid workflow. For that reason, I am much against upscaling in batches or in whichever automatic fashion. Each image is unique and requires an individual approach; and especially so, for anything to be called a work of art.
The steps in detail
Each step in this routine is done in 2-3 substeps.
Substep 1: pre-upscaling of the image. During AI-assisted upscaling with SD Upscale (SDU) or MultiDiffusion integrated (MD), the actual resizing of the image is always done by an upscaler model, not by an internal routine of the extension or the script (I will call them ‘methods’ from here on). Typically, the user simply chooses the Scale By factor, selects one of the available in the UI models, like UltraSharp, foolhardy_Remacri etc, sets all the other relevant upscaling parameters and clicks on Generate. In contrast, in this routine the ‘raw’ upscale operation is necessarily a separate substep; it’s done explicitly in Forge’s Extras, or using a standalone upscaler such as the highly recommended freeware upscayl, before proceeding to generate. This allows you to exercise a fuller control over the overall look of the eventual upscaled output, the grain or the texture, and also to prevent an unsolicited color shift. If you don’t separate this part, it will be impossible for you to determine in what degree the upscaler model influenced the eventual output. Forge comes with plenty of top-class models already built in, and you can always look for a specialized one fine tuned for the type of images you need to have upscaled (here’s the site that hosts practically every sort). For more details on the subject, see this recent discussion.
This approach of separation not only gives you more control of the output, but also significantly saves on the total computing time: once you have a raw-upscaled image with qualities closest to the way you want the upscaled image to look ultimately, the pre-upscaling operation won’t have to be performed at the beginning of every subsequent run of the method (and chances are that you are going to do a lot of trial runs at each upscaling step). Conversely, if the pre-upscaled image has a texture with a particular strong (synthetic) grain, or any artifacts of its own (which does happen occasionally), it might be difficult to alter that look within the adding detail run (substep 2), so choose wisely! (FWIW, the models used for upscaling the demo image for this routine were 4xLSDIRplusC, HAT-L_SRx4_ImageNet-pretrain and 4xHFA2k, they seemed to be suited better for the type of synthetic landscape photos used in this project than the others I tried; but that’s only my personal preference. In contrast, 4x_NMKD-Siax_200K proved unsuitable for this project, as this model tends to add too much noise in the upscaled output, making it appear unnaturally sharp.)
Note: the pre-upscaling factor of 2x at each step is only a default, for an even finer control, you might want to reduce it to 1.5 or even lower.
Timing. Pre-upscaling is usually done very quickly, it takes about 20-30 seconds for an average model to 2x upscale a 4K image on my RTX 4070 Ti Super. 2x upscaling of an 8K image might take from 1.5 or 2 minutes (4xHFA2k) to anything between 4 and 12 minutes using a slower model like SwinIR or HAT-L_SRx4.
Substep 2: adding detail to the pre-upscaled image with the chosen SD method and checkpoint. At this step, you use the pre-upscaled image as the source in the chosen Forge img2img method and run the process with the scale factor of 1. Depending on the Denoising strength parameter, the checkpoint used, the prompt etc, this generation substep will add a variable amount of detail into the rendered image (see more on the ways to control the amount and contents in ‘Forge webUI parameters’ below). For the demo image used in this guide, the details added have been of this variety: birds flying in the sky, features of the spire-shaped towers on the left and on the right, waterfall shapes, houses, flower petals, figures of people at a distance, sometimes a bicycle or a horse, and even a tiny village on the cliff that was formed during subsequent upscale steps. By experimenting on each step, you arrive at a rendering that contains newly added detail in the quantity and appearance which is most appealing to you. Once gotten that, you use the rendered image as the source for the next upscale step. Amazingly, as I witnessed more than once in my project, and as opposed to a more traditional img2img process, such an iterative process wherein an image is generated and then used as the upscale source again and again, will not cause any degradation of the subsequent output (when generated with the right set of parameters of course). The detail added on a detail-enriching step will usually be kept and further developed at the next one, given a carefully tuned set of parameters, and the sharpness will be retained without any visible softening of the texture.
Keep in mind though that processing time increases with each upscale step and the increased resolution, so it makes sense to do the most of the creative experimenting in the middle of the routine, at the level of 4K and 8K. Generating at the last 16K level should be done just to keep the detail already introduced, not to add any substantially new one (unless you have a super-fast GPU, of course).
Timing. Forge runs very, very fast when img2img-processing, with either of 1.5 or SDXL versions of checkpoints, processing a 4k image in about 1 minute, for either method. It takes between 2 and 3 minutes to process a 8K image, and between 8 and 18 minutes for a 16K image, with all the right parameters set. (Automatic, in comparison, takes anything from 1 to 3 hours to do the same with a SD 1.5 checkpoint, and the quality of the output is much harder to maintain.)
Substep 3 (optional): refining and fixing artifacts. You should be mindful of possible artifacts (small defects and off-color patterns), and particularly of visible tiles and seams that tend to appear in the generated image when you fail to moderate the process by means of lowering the denoise parameter and/or using the ControlNet Tile mode (more on this in the next part). Probability of the tiles becoming visible is also dependent on the image contents: images with a light blue sky or a smooth gradient of any kind are particularly vulnerable, as demonstrated by the example images in the demo folder. I learned the hard way that, except in a few cases, it’s practically impossible to get rid of the seams by any post-processing. Generally, you will have to discard an image with tiles and seams too prominent. Speaking of visible tiles and seams, I noticed that the MD method is more prone to that issue than the SDU one, while not being any faster in processing, so I recommend using the latter for most use cases.
That said, the artifacts such as visible tiles and seams, as well as minor blemishes, can be made less pronounced (if not completely removed) by running the substep 2 again with the just-rendered image as the input one, with a different checkpoint, the Denoising strength or CFG parameter adjusted. This substep is only needed if the upscale step is the last one in the sequence; otherwise, the substep 2 on the next level will most likely do this job. Also to consider: activating the Refiner option at the above substep, to be used with a secondary checkpoint (see below).
Check out the demo folder for the most striking examples of tiles, seams and other artifacts.
Forge webUI parameters
Stable Diffusion checkpoint
The choice of checkpoint is a major factor influencing the detail that will be added to the image during the generation process. Different checkpoints react differently to the input material, some hallucinate more readily with the same source than the others. The checkpoints used to produce the demo image in this guide were: albedobaseXL_v21, juggernautXL_v9Rundiffusionphoto2, sleipnirSDXLTurbo_v125, leosamsHelloworldXL50GPT4V, for the SDXL version, and juggernaut_reborn, photon_v1 and absolutereality_v181, for the v1.5 one. Since upscaling, as described in this guide, is a multi-pass process in which the checkpoint is freely changed at each step, all of them contributed to the final result to varying degrees.
Check out the demo folder for the most striking examples of hallucinations I encountered during this project.
LoRa
Specialized LoRas can also be used to influence the type and the amount of the detail added to the image, or the style it is rendered in (this is most likely how Magnific, Leonardo U-Upscaler and others of the kind support various styles available in their UI.) No LoRas have been used in this project, however.

Prompt
Compared to other SD-based solutions, the prompt plays a much lesser role in this routine. In fact, you can use the same prompt for each upscaling project, something like “masterpiece, best quality, highres”, and that will do it. As a rule, no specific terms or object names should be used in the prompt. The reason for that is that the large-size upscaling is always a tile-based process, wherein each tile is generated independently of others, so, if your prompt includes some specific object you want to have generated in the output, there is a high chance that that object will appear everywhere in the picture, or at least at every spot where the checkpoint ‘thinks’ it is appropriate. This holds especially for the MD-based upscaling with 1.5 checkpoints. For SDU under Forge using SDXL ones, it is less extreme, but I would still recommend avoiding specifics in the prompt. In this project, I went no further with the prompt than using “majestic fantasy vista, cinematic, high contrast, highly detailed”. Just inserting “mountainous” adjective before “vista” would cause mountains rendered in the dark parts of the sky and other strange features appearing in the picture, without much added realism.
In any event, due to the nature of the Stable Diffusion process, it is not possible to control what exactly the checkpoint will inject, and where, even with the best crafted prompt. You can, however, try restricting it from injecting something you don’t want it to, by including various synonymous terms in the negative prompt.
Sampling method (‘sampler’)
In this project, I consistently used two classical samplers, DPM++ 2M Karras, and, a bit less often, DPM++ 3M SDE Exponential, they seemed to be the fastest of the bunch and delivered desired quality with a relatively low step count of 20-22. Some other samplers, like Euler and HEUN, proved to be too eager to hallucinate bizarre detail into the image (with the same step count), so I avoided them; some others produced completely damaged output or were unacceptably slow.
Sampling steps
With a sampler chosen as above, the step count of 20-22 was sufficient most of the times for a good output quality. Occasionally, I would raise the count to 25 or 30, or even 50, but could never notice much difference in the output. Increasing the step count does make the generation take longer though, in almost linear fashion.

CFG Scale
The CFG parameter has a major influence on the output, augmenting the hallucination as you raise it. With that, however, also rises the chance of tiles and seams and other artifacts appearing, so it’s a good idea to be conservative with this value. As a rule, I would use a CFG no higher than 8 for a regular detail-adding generation, and restrict the value to 5 at the last (16K) step, to avoid undesired detail injection, while keeping the overall sharpness level. With the MD method and 1.5 checkpoints specifically, raising this value to extreme levels such as 13-15 and setting tile dimensions just above 100 pixels will cause a profuse injection of the sharpest detail possible into the output, which can often produce a stunning effect, but is generally hard to control (not to mention additional artifacts).
Denoising strength
The denoise parameter which is at the heart of this ‘creative’, img2img-based upscaling routine is the single most influential factor; you should use it within a pretty narrow range. The CFG, the sampler, the step count, the checkpoint and of course the prompt all play their role in the process, but the denoise value leads the way. Experimenting with it, you nudge the img2img generation to add a desired (relatively small) amount of detail, and no more. If you don’t restrict the value of this parameter, your image will contain a wild (‘insane’) amount of detail, particularly when upscaling with the MD method, which tends to insert in the image, depending on the checkpoint, all kinds of stuff (NSFW one including) at any spot imaginable. That is often accompanied by tiles appearing in the output image and other artifacts - which means, again, wasted time and effort. But visually, it can be great fun of course.
Recommended values (based on this project): between 0.28 (basic detail level, low hallucination) and 0.38 (new detail is prominent, checkpoint-dependent hallucinations across the image). The lowest level of 0.28-0.30, or lower, is recommended to use at the last, 16K step. See also ControlNet integrated below on how to dampen the effect of the denoise parameter and keep the output faithful to the original image.
Resize to, Width and Height / Resize by, Scale
This must be the most mystifying part of the entire Automatic/Forge interface. After all this time, I am still figuring out, shall we say, the subtleties of its logic.
The sliders labeled ‘Width’ and ‘Height’ play a different role under img2img-based upscaling than in a regular image generation. When upscaling with Forge’s SDU, with these sliders you don’t set the resolution you want the image to be upscaled to (it won’t allow values higher than 2048 anyway), but rather the tile dimensions used for upscaling/refining, see Tile configuration below. When running SDU script under Forge, make sure that the Resize to (NOT Resize by) dialog box is in foreground before clicking on Generate, or else it will take very long to process the image at 8K, and forever, at 16K. The image’s target dimensions are defined in SDU via its internal Scale Factor parameter.
In contrast, when upscaling with Forge’s MD, before clicking on Generate you need to ensure that the Resize by dialog box is in foreground, with the Scale factor set properly, or else it will just generate an image of whatever dimensions set by the sliders in Resize To, but luckily, in just a few seconds. For the purposes of this routine, the Scale can be set to 1.
And that is the simplest part of the puzzle, all kinds of things can go wrong if you set something in the UI that Forge developers didn’t really anticipate. To avoid excessively long runtimes and other pitfalls, follow the guidelines below when upscaling.
Tile configuration
Image tiles are the core part of the design of HR upscaling in Stable Diffusion, I believe it’s the only effective means to process large size images without running out of GPU memory (VRAM) very quickly.
In SDU, you set tile dimensions, as suggested above, in the Resize To dialog box. For SDXL checkpoints, I used the 1024x1024 dimensions, as well as 768x768 (the tiles don’t have to be aspect ratio-shaped), and for 1.5 checkpoints, the standard 512x512 dimensions, or 768x768, which worked equally well.
An important parameter in both methods used in the routine is Tile overlap, it defines the pixel width and height of the overlapping area of adjacent tiles. Making it as large as reasonably possible helps to tame the visibility of tile seams, by the price of slower computation. In my experience, an overlap of size 64 pixels for SDXL would suffice; smaller sizes could make sense for 1.5 checkpoints and in cases when visibility of tiles is not an issue. In any case, it’s a good idea to use the default value first.

The MD method, which includes its own set of sliders to define the tile configuration, has an additional parameter, Tile Batch Size. It defines how many tiles are held in memory simultaneously and processed in one basic operation; 8 is the maximum using which will supposedly achieve the highest speed of upscaling, lowering it will decrease the amount of VRAM used by this process. In MD under Automatic, setting this parameter lower than the default (to 4, 5 or 6) is an essential means to avoid running out of CUDA memory; in Forge, it’s of a lesser importance, since that system has its own, by all indications much more efficient memory management.
ControlNet integrated
To keep the upscaled/refined output as faithful to the source image as possible, ControlNet Tile resample mode is used. When this mode is activated, the effect of the Denoising strength parameter is dampened, which gives you a higher degree of freedom to play with the parameter without the associated risk of tiles and seams appearing, but at the price of longer (about 10-30%) processing times. In my experience, with the Controlnet Tile resample switched on under SDU, the Denoising strength could be set as high as 0.4, with no or little visible artifacts appearing in the output image.
To engage this option, enable ControlNet Unit 0 in the Forge img2img UI, check Pixel Perfect, select Tile in the Control Type combo, select Tile resample in the preprocessor dropdown box and the corresponding model in the next box, which is usually control_v11f1e_sd15_tile when using a 1.5 checkpoint and ttplanetSDXLControlnet_v10Fp16 when using a SDXL one (the only one that worked for me, might require explicit downloading and installing to Forge). Next, set Control weight to a value between 0.5 and 0.7 inclusive (this relaxes the ControlNet Tile fidelity, which we need for the purposes of detail-adding), and leave the rest of the ControlNet settings at the default.
Note that the MD + ControlNet mode combination, as I found, doesn’t really work under Forge: when both are selected, the process upscale starts quickly but then stagnates without any visible progress, for hours. (In contrast, the same combination works just fine under SDU, for both 1.5 and SDXL flavors.)
Other parameters in Forge’s img2img interface
Clip skip. Leave at the default. Changing this might make no impact whatsoever, I have never checked.
Resize mode. Leave at Just resize.
Refiner. This is an interesting option worth experimenting with. It allows the user to select a secondary checkpoint whose output will be mixed with that of the primary one, at a selected point of processing specified by the Switch at parameter (reasonable values between 0.6 and 0.85). Unfortunately, while potentially useful from the creative perspective, this option is too computationally costly, slowing down runtimes to anything from 2 (for SD 1.5) to 8 times (for SDXL checkpoints, which are larger). This happens due to constant checkpoint loading and unloading (a rather time-consuming operation) performed for every tile being processed.
Batch count / Batch size. Leaving these at 1 would be a practical choice, to avoid wasting your computing time - unless you want, say, to experiment with the Denoising strength at its higher values when upscaling at a low to medium image resolution.
Seed. Usually left at -1 to allow random variation of the output.
MultiDiffusion integrated. Enable this control when you want to upscale with this particular extension, as opposed to the SD upscale script. The choice of the specific Method between MultiDiffusion and Mixture of Diffusers does not affect the output that much (in my experience anyway), I understand it was retained in Forge for backward compatibility with MD under Automatic. An important related option: see Never OOM integrated below.
Never OOM integrated: when selecting MD extension for upscaling, it is necessary to synchronously enable this extension as well, and check the box labeled Enabled for VAE (always tiled), and not the other one above it. If this is not done, upscaling of a large sized image will last indefinitely long. In contrast, upscaling with SDU necessitates unchecking of that option and leaving Never OOM inactive, for exactly the same reason.
Script. Select SD upscale form the dropdown box when upscaling with SDU. In this case, MultiDiffusion integrated must be deactivated, or else neither of the two options will work properly. Also, when selecting SDU, make sure to deactivate Never OOM, as mentioned above. The Upscaler choice is up to your experimentation (see Substep 1 at the top), but for the purposes of this routine it is normally set to None.
All the other integrated extensions present in Forge’s interface are best to leave inactive.
Forge vs Automatic1111, SD 1.5 vs SDXL and the fate of Tiled Diffusion
Based on my experience in this upscaling project, a few general conclusions can be made. For the purposes of the project, Forge WebUI proved a much better choice, with either of the two methods: it runs significantly faster and its output is much less prone to visible tiling, seams and other artifacts than when using equivalent tools under Automatic. The MD implementation in Forge, however, is much incomplete, with important features, such as Noise Inversion, slow modes of Tiled VAE encoding / decoding and others left out, as compared to the Automatic version of MD (where it is called Tiled Diffusion btw). In my view, this drawback of Forge is largely compensated not only by faster runtimes but also by much more robust, stable performance, and most importantly much better tile management that practically solves the problem of visible tiles and seams (you won’t even find an option like Seams fix in Forge, it’s done behind the scenes and done exceptionally well), not to mention it allows to run highres upscaling on GPUs with 8 GB VRAM.
What’s more, support for v1.5 checkpoints in Froge feels somewhat incomplete, at least speaking of the MD/TD implementation. All in all, however, I feel that the MD/TD method is no longer relevant for HR image upscaling, seeing the drastic improvement of the SD upscale script. From my upscaling perspective, unless Automatic will be merged with Forge to take advantage of the improvements in the latter, the former remains relevant only for MD/TD-based upscaling with 1.5 checkpoints. It doesn’t help either that development of TD/MD has remained dormant for the last two months. (Which is sad, since SDXL support in MD, native or under Forge, has not been developed beyond only a nominal one - it doesn’t really work well with checkpoints of that version, as I found in the course of my project.)
Although, to be fair, an even more worrying picture holds for Forge development, which hasn’t seen any update since February.
The quality of SDXL-based generation as compared to that of v1.5 is a matter of a separate discussion; due to space constraints, I won’t go into that here. I will just add that personally I find SDXL-based upscaling superior to v1.5 one, for most use cases.
The folder with the complete selection of demo images from the project prepared for this post is available here.
https://preview.redd.it/3y1nwkod110d1.jpg?width=7680&format=pjpg&auto=webp&s=5c12e51fa2d44bb8336a7ca8c02094b349a61799
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2024.05.12 18:56 Mrereren Those who struggle with emotional numbness

How does Lamictal affect you? Does it help you feel more emotions or is it completely neutral in that regard? I find Lamictal to have a mild numbing effect and I wonder if it's just me or is it something that commonly happens with this med.
I'm on 200mg.
submitted by Mrereren to lamictal [link] [comments]


2024.05.12 14:49 Dillon_Wife Keep going?

Hi, started ability 2mg. Only took it for 2 days. I am an endless pit…want to eat eat eat and never feel full. I’m peeing way more and I cannot sleep. After only 2 days I think I’m going to stop. I’m on Lamictal and lexapro so I can handle side effects but this is the worst side effects I’ve ever had. Any insight? Did this get better for anyone? Thanks
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2024.05.12 10:20 KomturAdrian When should I be worried about my memory

Male 30 11/15/1993 139lbs Lamictal
For quite a few years I was having some minor memory problems and I think it’s gotten a lot worse for the past three or four years.
It’s nothing too terrible. But like I’ve helped my dad do a lot of work on his cars and I don’t really remember doing it. Last week I took an alternator and compressor off of my car and forget where certain pieces and bolts went. At work especially I will go off to do something, and then totally forget what that was, so it takes me a minute to remember.
I can have conversations with people and have almost immediately forget what it was we spoke about. I’m sure there are other examples. I think my family has even commented on my memory.
I do have a lot of racing thoughts. I thought maybe that was it. Too much focus on my thoughts. I overthink an awful lot as well.
Should I be concerned? My doctor shrugged it off as a side effect of my Lamictal, but I was having these problems prior to that, and I think that only exacerbated it.
What do they do and how do they test for this stuff? Sometimes they tell me three words to remember at the end of an appointment and I always get it right, but only because I constantly repeat it my head; idk if I would remember otherwise.
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2024.05.12 09:54 lucispito Trouble breathing

I was on Lamictal 100mg for 4 months. It didn’t give me any side effects at 25 or 50 but after we upped the dosage to 100 I started getting weird side effects. Like my head was itching 7/24 and I suddenly got dermatitis on my scalp. But most importantly I was gasping for air all the time. Also I was yawning all the time. The breathing issue was so bad it was waking me up from my sleep. I couldn’t walk for like 10 minutes without gasping for air like a fish. We did all of the tests and everything was ok. After 4 months I stopped taking it and my symptoms magically disappeared. But months later I started having minor issues with my breathing. It is definitely not bad as the months ago when I was using the Lamictal but still it scared the shit out me because I can’t go through this again. Is it possible that Lamictal made something to my brain permanently that affects my breathing? I also started lithium 8 days ago but my I think it has nothing to do with it.
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2024.05.12 09:00 wambulance33 Lamictal journey

I am very curious to understand more about your journey with Lamictal. What was your dosage titration like? Do you feel like it's the right dosage? Any side-effects both positive and negative? I could go on and on with questions but I imagine you understand.
Personally I was introduced to Lamictal after Seroquel was not handling the depressive episodes. I was told Lamictal would help fill that gap. It's been a very interesting journey. For example, I've never had a "psychotic" episode prior, but that isn't all bad. Mostly just auditory hallucinations and losing time. One of the tougher side effects is dreaming. Everything is so insanely vivid that I have to go back through my emails/texts/etc to have some idea what really happened and what was imagined. It has led to some awkward conversations. The most notable effect has been the ability to feel. I know I'm part zombie at this point and I don't care.
Just curious about your journey. Feel free to message me if you want to talk more specifically about meds and dosages.
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