High granulocyte

Help Interpreting Recent Blood Test Results

2024.05.15 07:45 Zealousideal_Card326 Help Interpreting Recent Blood Test Results

I recently received the results of some new blood work from my doctor, and I'm feeling a bit overwhelmed by the information. Unfortunately, I won't be able to see my doctor for a few weeks, so I'm turning to this community for some guidance.
Here's a bit of background: Following COVID-19 in 2020, I've been dealing with several health issues, including subclinical hyperthyroidism, insulin resistance, and PCOS with high testosterone levels. I've been experiencing constant symptoms like hair thinning, goiter, weight gain, hirsutism, rashes, flushing, and frequent illness. To manage these conditions, I've been prescribed Contrave and self treat with supplements like myo-inositol, spearmint tea, berberine, and a multi-vitamin. I see an endocrinologist who is reluctant to medicate and a holistic doctor who cannot prescribe.
Now, onto the recent blood test results. While my thyroid levels are finally optimal, there are several markers that are elevated and out of range, leaving me concerned:
WBC, Hematocrit, MCV, Platelets, Neutrophils Abs, Lymphs Abs, Monocytes Abs, EOS Abs, Immature Granulocytes (0%), Immature Grans Abs (0%), EGFR, Chloride
As usual, my insulin, glucose, and A1C levels are also elevated, along with my testosterone levels.
I'm reaching out to see if anyone here can offer some insight into what these results might indicate.
Or even just an idea of my doctor was looking for with these new tests.
I'd appreciate any advice or guidance you can provide. Thank you so much for taking the time to read this.
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2024.05.15 06:02 Angel_Eyes007 Pre-op lab work results & surgery is scheduled in 5 days!

So I completed the standard chest x-ray my dr required (nothing abnormal & no concerns that would have warranted it otherwise) & everything was fine. My lab work on the other hand showed my white blood count, platelet count, & granulocytes were high. I was on an antibiotic earlier this month for an unrelated issue to the bariatric process but I finished that about a week ago & have felt fine, with the exception of the stress of this 19-day pre-op liquid diet which has been tough. The results came through the patient portal but haven’t been reviewed by my dr yet. I’m worried my surgery (scheduled for Monday 5/20) will get cancelled or postponed. I emailed my dr’s nurse first thing this morning & she said she’ll get back with me as soon as the surgeon & Dr have reviewed them. Haven’t heard back yet & of course I’ve been agonizing over it all day. Has anyone had a similar experience?
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2024.05.13 23:56 juliaxyz 8 year old male - abdominal pain since February

Son 8.5 M, 45 lbs has abdominal pain since February. He doesn't go to school and stays in bed most of the time. It happened before but not as severe and went away after a month or so. We realize we need to wait longer for Amitripltyne to work but we are concened that he has rear good days (hours) and in bed most of the time. Normally he is a bright, fun and social boy and now doesn't leave his bed. Could this be something not tested for?
Current Outpatient Medications
famotidine 40 MG/5ML Recon susp - Take 2 mL (16 mg) by mouth at bedtime
gabapentin (Neurontin) 250 MG/5ML Solution Take 3 mL (150 mg) by mouth twice a day

hyoscyamine 0.125 MG Tab - does not help

amitriptyline 10 mg Tab - full dosage started May 2nd, makes him agressive

Medical History Summary:
8.5 years old has been constipating for many years. He has been diagnosed with encopresis in 2021. Ever since he was diagnosed with encopresis He was on MiraLAX .5 to .75 cup twice a day. This helped him to control his constipation. During all this time except for approximately a few weeks he was soiling his pants almost daily. He was also frequently complaining about abdominal pain. Per doctor’s recommendation we were reminding him to sit on the toilet after each meal. Feeding him with homemade meals and we try to limit processed food. We did physical therapy and psychologist therapy. He has a toilet foot stool and seat.
About 1 year ago (January 2023), a bowel cleanup was performed per Max’s pediatrician recommendations. One cupful of MiraLAX was given every 3 hours. (No fasting or clear food diet was recommended)
During that time evacuated lots of poops with diarrhea content. We did not achieve the yellow fluid and stopped after a couple of days. Since this cleanup Max experienced severe abdominal pain for about a month.
Per GI doctor recommendation, we were no longer doing cleanup to avoid severe abdominal pain. Instead, Max was back on his MiraLAX dose .75 cup twice a day with fiber gummies 4mg a day.
He has good apetite most of the time, except after a dose of Exlax. His stool was always help soft over these years.
Notes from GI visit April 22nd - Today he has more guarding, mild distension and tenderness. I can't tell if he has a surgical abdomen (ie volvulus, appendicitis) but it is not associated with vomiting or eating. His most likely diagnosis is abdominal migraines (abdominal pain and headaches) and anxiety at this point, but the pattern has been consistent without as much good days. Activity makes him worse, and we have considered ACNES as well. He has had multiple cleanouts, and the periodic soiling could be from inattentiveness. Perhaps this is from constipation, but should rule out surgical abdomen at this time. We had a long conversation today about abdominal migraines, but upon repeat exam, it is still quite guarded. Pain is daily / off and on. Has had 2 good days in last 3 weeks Appetite is good except when pain is high. No vomiting. Stooling daily with miralax. Sleeping well.
UPPER Endoscopy Diagnosis
A. Duodenum, mucosal biopsy:- Duodenal mucosa with no pathologic change. B. Duodenum, bulb, mucosal biopsy:- Duodenal mucosa with a small lamina propria lymphoid aggregate. C. Stomach, antrum/body, mucosal biopsy: - Antral-and oxyntic-type gastric mucosa with focal features of mild reactive (chemical) gastropathy. D. Esophagus, distal, mucosal biopsy: - Squamous epithelium with rare intraepithelial eosinophils (up to 2 per high-power field). E. Esophagus, proximal, mucosal biopsy:- Squamous epithelium with rare intraepithelial eosinophils (up to 1 per high-power field).
The overall findings are nonspecific. The esophageal findings do not meet threshold numerical criteria for a diagnosis of eosinophilic esophagitis. Reflux related changes are favored. Clinical correlation is recommended.

CT ABDOMEN PELVIS W CONTRAST

Narrative

IMPRESSION:Normal appendix. No CT evidence of inflammatory changes in the abdomen or pelvis. Moderate stool burden in the colon.NarrativeINDICATION: o appendicitis/abscess - GI requesting CT d/t guarding/distensionEXAMINATION: CT ABDOMEN AND PELVIS WITH CONTRAST - CT Abdomen And Pelvis W/ Contrast InjectionTECHNIQUE: Multiple axial images were obtained of the abdomen and pelvis following IV contrast. A radiation dose optimizationtechnique was used for this scan. DLP: 29.8 , CTDI vol: 0.63IV Contrast dosage and agent: 63 mL of Isovue 300Oral contrast: Administered.COMPARISON: None.____________________________________________FINDINGS:LOWER CHEST: Lung bases are clear without any infiltrate. No pleural effusion noted. There is no cardiomegaly or pericardialeffusion.LIVER: The liver has a homogeneous density. No focal masses noted. There is no intrahepatic biliary ductal dilatation.GALLBLADDER AND BILIARY TREE: No calcified gallstones. No gallbladder distension or wall edema. No intra- or extrahepaticbiliary ductal dilation.PANCREAS: No focal cystic or solid mass. There is no pancreatic ductal dilatation or peripancreatic fluid.SPLEEN: Normal size without focal cystic or solid mass.ADRENAL GLANDS: Normal.KIDNEYS AND URETERS: Both kidneys have a normal enhancement without hydronephrosis, renal cysts, masses or perinephric fluid.There is no hydroureter.PERITONEUM: No ascites or free air. No other fluid collection.BOWEL: No abnormal dilatation of the bowel loops is noted. Contrast is noted in several nondilated small bowel loops and in thecolon up to the splenic flexure. Moderate stool noted in the colon, including the rectum. Terminal ileum is visualized andappears normal. A normal caliber partially contrast filled appendix is seen in the right lower quadrant. A few scattered foci ofair also noted in the appendix. No adjacent inflammatory changes are seen. The appendix is best visualized on axial series #2,images 58-69/139.LYMPH NODES: No enlarged mesenteric or retroperitoneal lymph nodes.VESSELS: Vasculature appears normal. No stenosis or aneurysmal dilatation noted.URINARY BLADDER: Appears normal without wall thickening, mass or trabeculations.REPRODUCTIVE ORGANS: No pelvic masses.ABDOMINAL WALL: No discrete abdominal or pelvic wall hernia.BONES: No lytic or blastic abnormality.
Blood tests - Collection date: April 30, 2024 11:08 AM
Lactase 13.9 Normal value: >=14.0 nmol/min/mg Prot
Sucrase 51.0 Normal value: >=19.0 nmol/min/mg Prot
Maltase 201.3 Normal value: >=70.0 nmol/min/mg Prot
Palatinase 15.8 Normal value: >=6.0 nmol/min/mg Prot
Glucoamylase 24.2 Normal value: >=8.0 nmol/min/mg Prot

Sed Rate 9

Ferritin 24.7

C-Reactive Protein < .5

Lead, Venous, B <.1

White Blood Count 5.98

Hemoglobin 14.7

Mean Cell Volume 81.8

MCHC 34.5

Platelet Count 302

Red Blood Count 5.21

Hematocrit 42.6

MCH 28.2

RDW 12.4

MPV 8.8

Segmented Neutrophils (ABS #) 2.35

Final Absolute Neutrophil Count 2.35

Lymphocytes (ABS #) 3.8

Eosinophils (ABS #) 0.05

Immature Granulocytes (ABS #) 0

Monocytes (ABS #) .47

Basophils (ABS #) .03

Add: he has headaches on the right side and sensativity to light, not sure how often but at least several times a week.
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2024.05.11 15:22 JBush1993 Am I in danger?

Am I in danger?
I wanted to test out what 200 mg/week does to my body and these are the results. I don't want my test or estradiol to be that high so I am going to cut back to 160 mg/wk. (I had 775 test at 150 so I am aiming for 850). In the meantime, is my blood okay? I know that sometimes people have to go get blood drawn to reduce thickening. I see my A/G and SGPT are high and thats mainly what I am worried about. Thanks!
https://preview.redd.it/p4eo8lqftszc1.png?width=1032&format=png&auto=webp&s=50bb3cabb32f9489975ceded4602dbf7a488d5bf
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2024.05.11 00:08 justfloatingalong High DHEA-Sulfate

I'm a 27 year old female, 5'4", 175lbs, I take lamictal 200mg, and seroquel 100mg, I also vape nicotine
My last period (4/19-4/27) was extremely debilitating. I was in a lot of pain from cramps and extremely fatigued. Since then I've still felt extremely fatigued, bloated, and painful cramps. I went to the doctor 5/7. The doctor palpated my stomach and his impression was my pain was from constipation. He ordered blood tests and an intravaginal ultrasound.
The ultrasound results came back normal but said "pelvic free fluid: trace physiological fluid" (before I could get the imaging done I experienced such bad pelvic pain I collapsed on the ground...could an ovarian cyst have ruptured?).
Blood tests that came back normal: testosterone, CBC w/ differential, and hemoglobin A1c. Not sure if it matters but basophil % was right at high end of normal and absolute early granulocyte count was right at low end of normal.
DHEA-sulfate came back high. It said normal is 35-430ug/dL. Mine was 547.
I'm wondering what this could mean and what, if any, additional testing would make sense to do. Thank you for any advice and I can provide more health information/history if needed to bring more clarity.
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2024.05.10 19:31 RunningFNP Hematology referral threshold?

Hey all, back with another question/conundrum from the primary care land.
Have a young patient in their 40s, history of HTN, HLD, and migraine. The last 3 times she's had lab work spanning about 5 months timeframe she's had a persistently elevated WBC count. Everytime it's between 18 and 21 with high neutrophils and high immature granulocytes. Every time she's had no clinical signs of infection or sepsis, only minor complaints related to her migraines. All her other labs have been stone cold normal.
I don't love that she's having granulocytosis, especially in a young reasonably healthy individual. Been kicking around the idea of doing a hematology referral just to make sure I'm not missing some early precancerous signs. What's y'all's threshold for hematology referral in a patient like this?
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2024.05.10 15:16 Intelligent-Desk5937 Which blood tests are required for hairfall cause detection for 18M ?

Hi I have found a screening package for hairfall on an online diagnostic lab. The tests seems important and relevant but when I check the price of these tests in other trustworthy diagnostic labs near me, the prices are so high there. That's why I doubt the reliability of this online lab. Can anyone recommend me if all these tests are absolutely neccessary or can i i trim down some tests like ANA,CRP,SHBG,DHT and cortisol etc. They are very expensive. I am 18M and my hair falling for many years honestly.

Package Includes 43 tests

Thyroid Profile (T3, T4, UTSH)/TFT
Iron Profile
Complete Blood Count / Hemogram (CBC)
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2024.05.10 06:16 Inevitable_Health_78 Pathology smear results

Age 41
Sex M
Height 5'9
Weight 220
Race white
Duration of complaint less than one month
Location: blood
Current medications: None
The waiting game sucks. My husband is getting work up for possible CML vs infection. He had elevated monocytes and mylelocytes in his CBC, which prompted a visit to hematologist/oncologist for work up. His numbers were only slightly elevated.
WBC also slightly elevated but not crazy high. We found out during this work up that he also has pretty high blood pressure (like 150 range) (pending appt with cardiologist next week). I've been reading how there is a correlation between high WBC/mylocytes and high blood pressure. We received the below results back from the pathologist. Seems at the very least not moving the needle toward CML and maybe the abnormal WBC counts could be attributed to his high blood pressure? He forgot to ask the doctor this but will during his follow up next week.
Below is the wording of the pathology report, I figured maybe someone would have an option on whether to take it as good news or no news at all?
"The total leukocyte count is increased in number with monocytosis and left shifted granulocyte distribution. No blasts or morphologically abnormal lymphocytes are seen. Erythrocytosis is identified and the red cells are normocytic in appearance. The platelet count is within the normal range and the platelets are normal in appearance. Recommend correlation with clinical findings and other lab data."
Also - His inflammation marker was at a 2 if that means anything. He has no symptoms of anything
Include a photo if relevant
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2024.05.10 04:21 xmisszelda Elevated Liver Enzymes

Hi there. I’m looking for any insight on my current medical situation. Does my information look like any type of illness/medical issue that we haven’t found yet? I’ll put any info I can below. Thank you in advance!!!
25, Female 240lbs 5feet7in. 3 children ages 5,3,1 and one stillbirth I do not drink any alcohol and never have other than a drink or two years ago. I vape nicotine daily.
Diagnosed with POTS, ADHD, ANXIETY, MTHFR, and a clotting disorder with a prothrombin gene mutation (G 20210A mutation)
Notable symptoms: severe sweating all over especially when standing, I’m talking drenched and dripping. I think this is due to my POTS though. Fatigue often. Brain fog occasionally. Random stomach issues occasionally, large increase in weight gain over the last 9 months. Currently taking adderall XR (adhd), buspar (anxiety), Effexor (anxiety), and propranolol (for POTS). my stress level is very high and I am consistently stressed but nothing I can do to help it anymore than I’ve already done. Random dizziness, tiredness, sweating, feeling hot but skin ice cold, all of these can be related to my POTS though.
I have had some abnormal blood test/labs for over a year now, and not sure what the cause could be. Specifically, my liver enzymes have been quite elevated for over a year and half. We have done a livegallbladdebile tract/ ultrasound and the only “abnormal” finding was very minimal fatty liver. Thyroid is normal. Cardio testing recently with echo & stress test. All normal other than my POTS.
My most recent blood test results:
Liver Panel
ALBUMIN 4.8
ALT (SGPT) 27
AST (SGOT) 26
BILIRUBIN DIRECT <0.2
BILIRUBIN TOTAL 0.8
GLOBULIN 2.3
ALKALINE PHOSPHATASE 270 (HIGH)
PROTEIN TOTAL SERUM/PLASMA 7.1
GLUCOSE 79
CREATININE 0.73
SODIUM 139
POTASSIUM 4.0
CHLORIDE 101
CALCIUM 9.7
BUN 16
CO2 25
CHOLESTEROL TOTAL 199
HDL CHOLESTEROL 47
CHOL/HDLC RATIO 4.23
TRIGLYCERIDES 53
LDL CHOLESTEROL 141
CBC (DIFF/PLT)
WBC 12.9 (HIGH)
RBC 4.84
HEMOGLOBIN 14.1
HEMATOCRIT 42.8
MCV 88
MCH 29
MCHC 33
RDW 13.8
PLATELET 372 (HIGH)
MPV 10.5
ABS NUET 8.99 (HIGH)
ABS LYMPH 2.8
ABS MONO 0.9
ABS EOS 0.1
ABS BASO 0.1
ABS IMM. GRANULOCYTES 0.05
NEUT:SEG+BAND % 70
LYMPHOCITE% 22
MONOCITE% 7
EOSINOPHIL% 1
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2024.05.06 01:10 NoSheepherder5025 Blood test after 8 weeks TRT

Blood test after 8 weeks TRT
Hey guys, so I have been on TRT for 8 weeks now. My results are looking pretty good, I inject twice a week, Monday and Thursday. 160mg of test c a week. I would say I feel pretty good most of the time at this level. I workout 5 days a week and eat decent but not perfect ( working on it ). I do however feel some days I still feel really tired and feel muscle fatigue. I am wondering if my E2 is too high or something? Or if it’s in a good range?
I am afraid to take an AI and crash it as I’ve read all the horror stories of crashed E2. Anyways I would appreciate any insight, thanks.
On another note, I was thinking of raising my dose to 200mg a week to see if a higher test level would feel better.
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2024.05.03 15:38 Breakitdownforyou Look how much NAC reduced my liver enzymes!

For those wondering, yes I’m on TRT. Liver enzymes were high due to fibrosis caused by Hep C which was cured years ago. Thank you ND!
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2024.05.03 15:36 Breakitdownforyou 8-9 week labs. RBC too high or barely a concern?

8-9 week labs. RBC too high or barely a concern?
80mg T x2 a week. 250iu HCG on pin days. For those wondering I lowered my liver enzymes using NAC. I have fibrosis caused by Hep C which was cured years ago using Epclusa. I feel amazing since starting TRT!
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2024.05.03 04:46 MolassesDizzy883 Smudge Cells Present - 22M. Bone Marrow biopsy showed no evidence of MDS / Leukemia

Possible Infection last week:

Last friday (04/26/2024) I (22M) started feeling sick with these symptoms:
I did not have respiratory symptoms such as:
I had a CBC done with manual smear differential done to differentiate my symptoms from infection, vs a possible autoimmune flare up (currently undiagnosed for autoimmune but highly suspected)

These were my results:

CBC

WBC 6.81 ( 3.91-8.77 10^3/uL)
RBC 5.22 (4.00-5.89 10^6/uL)
Hemaglobin 14.4 ( 12.1-17.4 g/dL)
Hematocrit 45.9 (38.4-53.4 %)
MCV 87.9 (85.3-101.2 fL)
MCH 27.6 (27.2-32.8 pg)
MCHC 31.4 ( 30.3-33.8 g/dL)
RDW-CV 13.0 ( 11.4-15.1 %)
Platelets 241 (151-304 10^3/uL)
MPV 10.4 ( 9.7-11.9 fL)

Manual Differential:

Granulocytes % 41.8 40.3-74.8 %
Bands % 3.1 3.0-7.0 %
Lymphocytes % 31.6 25.0-33.0 %
Monocytes % 15.3 4.4-12.3 %
Eosinophil % 1.0 1.0-3.0 %
Basophil % 2.1 0.0-1.0 %
Myelocytes # 1.0 None
Myelocytes % 1.0 None
Metamyelocytes % 1.0 None
Smudge Cells # 13 None
Giant Platelets % 1 None

Important Details:

What are possible causes for presence of Smudge Cells and immature myeloid precursors besides leukemia?

I had mono 2 years ago, which went away. No one in my social network has reported having mono in the last few months.
I also have history of chronic neutropenia and leukopenia (this WBC is much higher than my usual count). Because of this, I've seen a hematologist, done a bone marrow biopsy, which showed no evidence of MDS or Leukemias.

Medical History with chronic issues

Symptoms:
Diagnosed Conditions:
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2024.05.02 19:57 JBZtorks 100mg Test C per Week Bloodwork

100mg Test C per Week Bloodwork
How am I looking fellas?
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2024.05.02 19:57 JBZtorks 100mg Test C per Week Bloodwork

100mg Test C per Week Bloodwork
How am I looking fellas?
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2024.05.02 02:13 thotpocket323 Next steps- advice?

Next steps- advice?
(sorry the pic quality is so crappy, they’re all screenshots) Any insight any of y’all can give out of personal experience/knowledge or whatever, would be greatly appreciated!
So I’ve been feeling pretty bad for a long time. For some background, I’ve had a few different weird rashes for basically my whole life that no one could really figure out the cause of. After seeing a few different dermatologists, their best guess was a combination of allergic dermatitis, eczema, and dermatographism, which I was diagnosed with at around 5/6. I was diagnosed with celiac (EGD/biopsy) at 17, and POTS at 18. I also had a transient immune deficiency as an infant but grew out of it. Since going gluten free, my hives and eczema have calmed down a lot but I still get a rash, particularly on my face (shown in pics). My transglutaminase is back to normal, but I’m still having a lot of symptoms which I had originally thought were all due to the celiac (but obviously aren’t).
Symptoms include absolutely crushing fatigue, brain fog, GI/motility issues with horrible bloating, joint/muscle pain-feels like growing pains?, constantly feeling feverish, weight gain, temperature regulation issues, etc. I feel very sick when I’m in the heat, especially under sunlight. I also get sores on my scalp that worsen with sun exposure. Generally I just feel like shit lol.
I’ve seen immunology/allergy, GYN, neuro, without many results. My GI doc grew concerned when I had been completely gluten free and my inflammation was still elevated. Him and derm were both leaning towards another autoimmune. My GI has done 2 endo/colonoscopy, stool samples, blood tests etc to rule out any IBD. After all of this, he referred me to rheum. Rheum was pretty dismissive, and told me from the beginning of the visit that she was in a hurry, which she made very obvious. She told me that my inflammation markers were not much of a concern, but didn’t mention any of the other abnormal blood test results. She ordered some more testing (metabolic, ana, thyroid etc) and said that none of the abnormalities were a concern.
Not sure where to go from here, I don’t know what sort of specialist, if any, I should be seeing, I don’t know if this is autoimmune or something else? I’m tired of feeling this sick… ykno? If anyone’s situation is similar, you have any thoughts/advice, that would be awesome!! Thanks y’all :)
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2024.04.30 20:13 semerick1122 High Granulocyte and WBC blood count in CBC

My 26 year old son, over 200 lbs, 5'9", white, no symptoms, medical issues or current medications, does not smoke, uses alcohol socially and does not use drugs went from a negligible Granulocyte blood count in his CBC over a year ago to now having a 6.9 which is at the very top of the range. His WBC is 8.7 also on the higher end of the range. The Dr. has been blowing this off as not important for several months. Should my son be looking for another doctor?
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2024.04.28 15:27 butters--77 Sex-specific differences in myocardial injury incidence after COVID-19 mRNA-1273 booster vaccination

https://onlinelibrary.wiley.com/doi/10.1002/ejhf.2978
Hospital employees scheduled to undergo mRNA-1273 booster vaccination were assessed for mRNA-1273 vaccination-associated myocardial injury, defined as acute dynamic increase in high-sensitivity cardiac troponin T (hs-cTnT) concentration above the sex-specific upper limit of normal on day 3 (48–96 h) after vaccination without evidence of an alternative cause. To explore possible mechanisms, antibodies against interleukin-1 receptor antagonist (IL-1RA), the SARS-CoV-2-nucleoprotein (NP) and -spike (S1) proteins and an array of 14 inflammatory cytokines were quantified. Among 777 participants (median age 37 years, 69.5% women), 40 participants (5.1%; 95% confidence interval [CI] 3.7–7.0%) had elevated hs-cTnT concentration on day 3 and mRNA-1273 vaccine-associated myocardial injury was adjudicated in 22 participants (2.8% [95% CI 1.7–4.3%]). Twenty cases occurred in women (3.7% [95% CI 2.3–5.7%]), two in men (0.8% [95% CI 0.1–3.0%]). Hs-cTnT elevations were mild and only temporary. No patient had electrocardiographic changes, and none developed major adverse cardiac events within 30 days (0% [95% CI 0–0.4%]). In the overall booster cohort, hs-cTnT concentrations (day 3; median 5, interquartile range [IQR] 4–6 ng/L) were significantly higher compared to matched controls (n = 777, median 3 [IQR 3–5] ng/L, p < 0.001). Cases had comparable systemic reactogenicity, concentrations of anti-IL-1RA, anti-NP, anti-S1, and markers quantifying systemic inflammation, but lower concentrations of interferon (IFN)-λ1 (IL-29) and granulocyte-macrophage colony-stimulating factor (GM-CSF) versus persons without vaccine-associated myocardial injury.
777 hospital staff participants. 2.8% vaccine induced myocardial injury.
First, our findings confirmed the study hypothesis. mRNA-1273 booster vaccination-associated elevation of markers of myocardial injury occurred in about one out of 35 persons (2.8%), a greater incidence than estimated in meta-analyses of hospitalized cases with myocarditis (estimated incidence 0.0035%) after the second vaccination.
Safe & . . . . . . .
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2024.04.28 00:53 melon_with_a_y Blood test results

Hello! I am female, age 23, 5’2”, and 136lbs. I recently visited an urgent care a couple months ago for sinus issues and when he took my blood pressure he said it was high (i believe it was 140/85). I sighed and laughed and said i have a lot of anxiety, which I do. He told me that even with anxiety it wasn’t normal and to visit my primary care doctor.
Within this time an ENT diagnosed me with TMJ in my jaw (have no clue if that is important here but oh well).
A month later i see my primary care doctor and he started me on 5mg of lexapro because he noticed i did in fact have a lot of anxiety. He did say that my blood pressure was in fact high, and my heart rate was high as well. But he didn’t see any swelling in the ankles or neck area. He didn’t notice an irregular heart rhythm either. I told him i felt pressure in my chest lately. He told me he wanted me to track my blood pressure every day, get blood work done, and then visit him again.
Tests done:
TSH WITH REFLEX TO FREE T4 IF ABNORMAL
CBC W/ AUTO DIFFERENTIAL
COMPREHENSIVE METABOLIC PANEL
LIPID PANEL
Looking at the results in my account, i can see that all of them are in normal range from my basic understanding, but a few i noticed are a little on the higher side of “normal” — one almost not normal anymore. I wondered if that means anything???
Ones I’m concerned about:
RBC - 4.89 (Normal range: 4.00 - 5.20 x10*6/uL)
Immature Granulocytes %, Automated - 0.9 (Normal range: 0.0 - 0.9 %)
Lymphocytes % - 36.5 (Normal value: 13.0 - 44.0 %)
Monocytes % - 7.6 (Normal value: 2.0 - 10.0 %)
If you could give any insight that’d be great! I have a follow up appointment this Tuesday and obviously i’ll be discussing all this with my doctor. I’m just an insanely curious person and love learning how the human body works. Thanks for reading!
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2024.04.26 23:37 poeptor High RDW - Blood Test Results: Second Opinion

Hi Reddit! 🫶🏻
Requesting a second opinion; don’t want to come off with my doctor as some kind of hypochondriac so any help would be much appreciated.
Eight months ago, my doctor ordered a blood test due to joint/nerve pain and extreme fatigue. My muscles were/are sore, and in the mornings and evenings, my legs so tired and painful that I am sometimes unable to walk.
The doctor said everything was okay, except for a higher level of vitamin B6. He asked if I was taking multivitamins; I was at that time (normal dose) and have stopped taking them since then. These past months have not shown any improvement, it became even worse and I feel unable to cope with it anymore. I eat healthily, including vegetables, fruit and meat daily. I try to move as much as I can; while I’m on the move, it gets better (‘ok’), but only for a little bit before I am just too tired to stand on my legs and my whole body seems to lock up when in rest. Whatever I do, I do not seem to be able to improve my physical condition.
This led me to examine my results a bit more closely to see if I could find any clues, however small they might be; something I could do or change—something I might not have thought of yet. I noticed the high RDW (43) - but the rest seems normal, although I barely know anything about this.
I don’t have the units; they didn’t include them in their report to me.
Tl:dr - done a bloodtest 7 months ago; doctor said all OK 👌 - My RDW seems to be 43,4% rest looks ok, as far as I can tell; but there is a lot of different info online.
Could I possibly have anemia? What causes a high RDW, can it be an anomaly?
I understand anemia is multiple readings combined, so since it’s only a high RDW.. what does it mean?
Disclaimer: I translates the results from Dutch to english, for some of the lab tests name. I think I used the correct terms, but if not.. this is why. If an image of the resulta is better, lmk!
Alanine Aminotransferase (ALT; SGPT), 28
Blood Albumin, 40
Basophils, Absolute, 0.02
Erythrocyte Sedimentation Rate (ESR), 2
CKD-EPI eGFR, >90
Calcium, 2.29
Creatine Phosphokinase (CPK), 82
Creatinine, 83
Eosinophils, Absolute, 0.15
Red Blood Cells (Erythrocytes), 4.8
Ferritin, 175
Fasting Glucose, 5.8
Hematocrit (Hct), 0.46
Hemoglobin (Hb), 9.3
Potassium, 4
White Blood Cells (Leukocytes), 7.7
Leukocyte Differential, SCREEN
Lymphocytes, Absolute, 1.51
Mean Corpuscular Hemoglobin (MCH), 192
Mean Corpuscular Hemoglobin Concentration (MCHC), 20.4
Mean Corpuscular Volume (MCV), 94
Monocytes, Absolute, 0.86
Sodium, 141
Neutrophils, Absolute, 5.18
Red Blood Cell Distribution Width, 43.4
Thyroid Stimulating Hormone (TSH), 1.7
Platelets, 221
Vitamin B1 (Thiamine), 181
Vitamin B12, 339
Vitamin B6 (Pyridoxine), 123
Vitamin D (25-OH), 93
Immature Granulocytes, 0.02
(Possible relevant: HRV (Heart rate variability) is between 12-18. Once 21)
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2024.04.26 04:06 luckyjicama89 Edema, chest pain, positive D-dimer… no embolism. What’s going on? I’m struggling and tired

Went to ER visit:
35yr old female/ 150lbs/ smoke slightly elevated BMI, not diabetic.
I was in Mexico, fell down, and woke up with neck pain and level 2/3 ankle edema with rash on lower right leg X 4 days
They did a CBC that was unremarkable, besides a low BUN
Metabolic panel unremarkable
D-Dimer POSITIVE
Pregnancy test NEG
Blood pressure was 151/89 (not normal for me) Usually around 120/80
About a month ago had an ANA test that was positive, but just below criteria for Autoimmune disease.
An MRI was performed, NEG for blood clots.
Immature granulocytes were elevated beyond what’s the “high normal”
And I was sent home. Diagnosis was “lower right quadrant abdominal pain” lol (not what I was there for, but hey) and they referred me to the gynecologist… no idea why.
So no pulmonary embolism, and blood tests were generally ok. I’m testing positive for AnA, 1:60, have swelling and pain, tired all the time, and I’ve had a cough for the last 4 months but I am a smoker.
What is causing this? Data seems to point towards an unhealthy amount of inflammation, but no diagnosis. If any of the puzzle pieces could be put together, I might be able to advocate for myself to my PCP for further testing.
Thank you docs and nurses!
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2024.04.24 20:34 Every_Invite_8457 Blood work questions

Blood work questions
Any body know what this could mean
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