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F/5'6"/30 A few years ago I went from 232, my highest weight, to 199. I was so proud of myself but it's like the minute I hit that huge milestone I reverted and now I've made it to my new highest weight ever, 240 (generally hovering between 235-240). I went to the doctor because I wasn't feeling well and I've been pre-diabetic for a long time so I was worried it was full diabetes. The blood work came back and I was still pre-diabetic but also my cholesterol/triglycerides are extremely high. I have a follow up appointment to discuss that on Monday but I've been trying to get on a better path this past week until the appointment.
One of my main issues is I don't make a lot of money AND I'm terrible at cooking. Fresh fruits and veggies tend to go to waste and meats sit in my freezer until their frost burned. I can't plan ahead well so I end up not grocery shopping so I don't end up with a bunch of wasted ingredients. I end up going to pre-prepared meals, frozen meals, or fast food. I'm certain this is the reason for the cholesterol issue. I also crave warm hearty foods most of the time so things like salad are so unappealing to me.
Somebody I know gave me a box of premier protein shakes because they didn't like the taste. I've been drinking that for breakfast and I'm finding it's so nice to not have to decide what to do for a meal-- and it also made me feel full and it's got a lot of protein which I know I'm terrible at getting on a daily basis. I never cared much for breakfast anyway, but then I would be starving by lunch and would overeat.
I've decided to try Huel for a protein drink in the morning and also their savory food options so I don't have to cook or make too many decisions. I know whole foods would always be better but if it comes to cold food or cooking vs getting a $5 Wendy's meal, I'm afraid at this point I would choose the Wendy's. 😭 I'm hoping that making a few better choices (BETTER not BEST) will get me back on the right path. The Huel stuff is coming tomorrow so I guess we'll see how it goes.
It's not going to be enough of a solution for all my meals for the next month though, so I have a question. Can you guys recommend to me hot meals that are easy to prepare, easy to take to work, not very expensive, and not high in sodium or cholesterol? Around 500-700 cals? Huel shakes and meals are 400cals each so if I replace two meals with those, I only need one meal and maybe a snack—1500/1600 is a good calorie deficit for someone with a sedentary lifestyle to lose weight, right? Maybe? I don't know, I feel so overwhelmed right now. I am absolutely accepting criticism and corrections so please feel free.

The ophthalmic packaging market is poised for impressive growth, with estimates suggesting a CAGR of around 12% by 2027. This surge is driven by several factors. Firstly, a growing number of people are diagnosed with eye conditions like dry eye and conjunctivitis, requiring specialized packaging for ophthalmic products. Secondly, stricter regulations on recycling packaging materials are pushing innovation for sustainable and recyclable options in this industry. Furthermore, brands are increasingly using unique and functional packaging to stand out and improve product shelf life. Finally, the rise of emerging economies, a growing global population, and heightened awareness of eye health create exciting new opportunities for ophthalmic packaging companies in the years to come.
To know more about this study, request a free sample report @ https://www.researchcorridor.com/request-sample/?id=147356
Market Trends:
Response to Rising Eye Disorders: The increasing prevalence of eye diseases like dry eye and glaucoma is driving demand for innovative packaging solutions. This includes developing single-dose and multi-dose containers that ensure sterility, ease of use, and proper medication adherence for patients.
Sustainability and Regulatory Compliance: Stringent environmental regulations and a growing focus on eco-friendly practices are pushing for the development of recyclable and biodegradable ophthalmic packaging materials. This trend also includes optimizing package size to minimize waste.
Focus on Patient Convenience and Safety: Ophthalmic packaging is evolving to prioritize patient convenience and safety. Examples include tamper-evident seals, child-resistant closures, and braille labels for visually impaired users. Additionally, single-dose packaging is gaining traction due to its ease of use and reduced risk of contamination.
Brand Differentiation and Innovation: In a competitive market, pharmaceutical companies are using packaging as a tool for brand differentiation. This includes using unique shapes, colors, and graphics to enhance brand recognition and product appeal. Additionally, advancements in material science are leading to the development of ophthalmic packaging with improved barrier properties and functionality.
Emerging Markets and E-commerce: The rise of emerging economies with growing populations and increasing disposable income is creating new opportunities for ophthalmic packaging companies. Furthermore, the growth of e-commerce for prescription medications is necessitating packaging that can withstand the rigors of shipping and ensure product integrity.
Market Opportunities:
The ophthalmic packaging market is brimming with opportunities. The growing burden of eye diseases fuels demand for innovative solutions. Companies can capitalize on this by developing single-dose and multi-dose formats that prioritize sterility and ease of use. Sustainability is another key driver, with opportunities in developing eco-friendly and recyclable materials. Meeting patient needs is crucial, with child-resistant closures, braille labels, and user-friendly single-dose packaging offering a competitive edge. Furthermore, in a crowded market, unique and functional packaging can enhance brand recognition. Finally, the rise of e-commerce and emerging economies presents exciting prospects for companies that can deliver ophthalmic packaging solutions that ensure product safety during transport and cater to new markets with growing populations. By focusing on innovation, sustainability, and patient-centric design, ophthalmic packaging companies can solidify their position in this thriving market.
According to the recent report published by RC Market Analytics, the Global Ophthalmic Packaging Market is expected to provide sustainable growth opportunities during the forecast period from 2024 to 2030. This latest industry research study analyzes the ophthalmic packaging market by various product segments, applications, regions and countries while assessing regional performances of numerous leading market participants. The report offers a holistic view of the ophthalmic packaging industry encompassing numerous stakeholders including raw material suppliers, providers, distributors, consumers and government agencies, among others. Furthermore, the report includes detailed quantitative and qualitative analysis of the global market considering market history, product development, regional dynamics, competitive landscape, and key success factors (KSFs) in the industry.
Browse the Full Report Discretion @ https://www.researchcorridor.com/ophthalmic-packaging-market/
Geographically, the ophthalmic packaging market report comprises dedicated sections centering on the regional market revenue and trends. The ophthalmic packaging market has been segmented on the basis of geographic regions into North America, Europe, Asia Pacific, Latin America, and the Middle East & Africa. Ophthalmic packaging market estimates have also been provided for the historical years 2020 to 2023 along with forecast for the period from 2024 - 2030.The report includes a deep-dive analysis of key countries including the U.S., Canada, the U.K., Germany, France, Italy, China, Japan, India, Australia, Mexico, Brazil and South Africa, among others. Thereby, the report identifies unique growth opportunities across the world based on trends occurring in various developed and developing economies.
The Ophthalmic Packaging Market Segmentation:
By Dose:

• Single Dose
• Multi-Dose

By Type:

• OTC
• Prescription

By Material:

• Plastic
• Glass
• Others

By Region:

• North America
• Europe
• Asia Pacific
• Latin America
• Middle East & Africa

Leading players in the global ophthalmic packaging market include Amcor, Gerresheimer, West Pharmaceutical Services, Schott AG, and Becton Dickinson. These companies are driving growth through various strategies such as geographic expansion, investment in innovative packaging solutions, and forging strategic collaborations. This multi-faceted approach allows them to tap into new markets, develop advanced packaging options, and leverage synergies to gain a competitive edge.
To know more about this study, request a free sample report @ https://www.researchcorridor.com/request-sample/?id=147356
Key Questions Answered by Ophthalmic Packaging Market Report:

• Product popularity and adoption based on various country-level dynamics
• Regional presence and product development for leading market participants
• Market forecasts and trend analysis based on ongoing investments and economic growth in key countries
• Competitive landscape based on revenue, product offerings, years of presence, number of employees and market concentration, among others
• Various industry models such as SWOT analysis, Pestle Analysis, Porter’s Five Force model, Value Chain Analysis pertaining to Ophthalmic Packaging market
• Analysis of the key factors driving and restraining the growth of the global, regional and country-level markets from 2020-2030

About Us:RC Market Analytics is a global market research firm. Our insightful analysis is focused on developed and emerging markets. We identify trends and forecast markets with a view to aid businesses identify market opportunities to optimize strategies. Our expert’s team of analysts’ provides enterprises with strategic insights. RC Market Analytics works to help enterprises grow through strategic insights and actionable solutions. Feel free to contact us for any report customization at sales@researchcorridor.com.
Media Contact:
Company Name: RC Market Analytics Pvt. Ltd. Contact Person: Vijendra Singh Email: sales@researchcorridor.com Visit us: https://www.researchcorridor.com/

I just bought Eos energy enterprises as its only valued in the hundreds of millions but the US China trade war will see increasing tarrifs on China as well a subsidies for US renewable companies to encourage rapid growth of the sector... The US will wish to compete with China which already has massive industrial capacity and installed more solar in China in 1 year than the US did in 10 years, the US market is small has room for growth and the US will wish the renewable ecosystem grow massively so they can export to other countries and compete on an equal footing
To do that to transition energy grids to renewable it requires massive battery storage investment and so over the next few years sales will grow massively. Even in a diversified renewable system with hydro electric solar wind etc batteries are crucial.
I've bought albermarle a while ago for lithium mining as the price wil rise due to an EV requiring 10 to 60kg of lithium per battery and a phone only requiring amounts in the grams.
Renewable batteries on scale for grid storage will therefore be zinc or sodium.
And so I also bought Eos energy enterprises which makes zinc batteries for grid storage.
I think they'll increase sales particularly in Europe and the UK as well as further abroad on islands etc
https://www.eose.com
There website is pretty good, explains their products well. Although I get the impression they see themselves as emergency storage and not long term permement solution which they will absolutely be used as in grids with a high proportion of renewable as they're just so easy to add new batteries and replace old ones.

53M. 6'1". 185lbs.
Medications:
Aspirin
Atorvastatin (Lipitor)
Bepreve (bepotastine besilate ophthalmic solution)
Celecoxib (Celebrex)
Cialis
Diclfenac Sodium Topical
Losartan Potassium
Metoprolol Succinate Extended-Release
Zepbound
Naproxen Sodium (Aleve)
Nasonex
Sertraline (Zoloft)
Doctor recommended a cardiac CT angio and I received the results. This looks pretty scary. I mean, 99% of people have better hearts? I feel like I should just give up and wait to have the inevitable heart attack.
Here's the report:
CTA CORONARY ARTERIES 3D WITHOUT AND WITH CONTRAST
HISTORY: Coronary arteriosclerosis.
COMPARISON: CT calcium score from 04/30/2016 and 12/09/2020
TECHNIQUE: Gated CT angiography of the heart was performed with intravenouscontrast, using coronary protocol. Multiplanar reformatted and 3D maximumintensity projection (MIP) images were created and reviewed. The followingdose reduction techniques were utilized: automated exposure control and/oradjustment of the mA and/or KV according to patient size, and the use of aniterative reconstruction technique.
CONTRAST: Isovue 370 95 mL
FINDINGS:
CALCIUM SCORING:Left main: 65
Left anterior descending: 227
Left circumflex: 346
Right Coronary: 288
Posterior Descending: 0
TOTAL CAC SCORE: 926
AGE/SEX MATCHED SCORE PERCENTILE: 99% of asymptomatic patients matched for same sex and age have a lower calcium score.
CT CORONARY ANGIOGRAPHY:
LEFT MAIN: The left main coronary artery demonstrates calcified plaques which results in no significant luminal narrowing.
LEFT ANTERIOR DESCENDING CORONARY ARTERY: The proximal LAD demonstrates calcified plaques which results in minimal luminal narrowing (less than25%). The mid and distal LAD are patent without stenosis. The first diagonal branch demonstrates mixed noncalcified and calcified plaques which results in minimal luminal narrowing (less than 25%). The second diagonal branch demonstrates calcified plaques which results in minimal luminal narrowing (less than 25%).
LEFT CIRCUMFLEX CORONARY ARTERY: The proximal left circumflex demonstrates calcified plaques which results in minimal luminal narrowing (less than25%). The first obtuse marginal branch is small in caliber and difficult to assess. The second obtuse marginal branch appears patent. The third obtuse marginal branch appears patent. The mid left circumflex demonstrate scalcified plaques which results in minimal luminal narrowing (less than25%). The fourth obtuse marginal branch appears patent. The distal leftcircumflex is small in caliber and cannot be assessed.
RIGHT CORONARY ARTERY: The proximal RCA demonstrates calcified plaques which results in mild luminal narrowing (25-49%). The mid RCA appearspatent without stenosis. The distal RCA appears patent without stenosis.The PDA arises from the RCA and appears patent. Other: There is a 5 mm pulmonary nodule in the right lower lobe (series 14,image 41). The heart size is normal. There is no pleural or pericardial effusion.
IMPRESSION: 1. Nonobstructive coronary artery disease.2. Calcium score of 926.3. A 5 mm right lower lobe pulmonary nodule. Recommend a follow-up noncontrast CT chest in 1 year.

We are doing a prac in Biology and I am having difficulty using my immobilized amylase in different concentrations of sodium alginate(they make like little amylase balls) and then they are dropped it a calcium solution and stored so they can solidify. Basically my independent variable is changing the concentrations of sodium alginate, how the hell do I link this to a wider application? any ideas chat?

Hey!! Im dealing with a small amount of fleas, Ive given all bathable animals a flea bath and sprayed my dogs down in a non pesticide flea spray. I found the flea spray at a pet smart but they didnt have a non pesticide flea spray for cats. The ingredients on the bottle say theres peppermint oil, eugenol, sodium lauryl sulfate, and sodium benzoate. My first question is could I use this one the cats? if not, can anyone recomend a brand from a US store thats not to pricey? or does anyone knows a home remedy that helps repel fleas and/or kills fleas and the eggs and larve? I am short on money right now the other flea stuff I bought was quite expensive. I have sprayed the cats down in a vinegar and water solution to help repel them but Im not 100% sure it works and want some outside advice. Thank you all!!

While many if not most people would find windowless apartments preposterous, it may be possible that high enough percentage of people would be willing to be without windows if that saves them money or for some other advantage. Remember that people can have stranger desires and acceptances than that. North of arctic circle in winter, windows have little use anyway. If somebody spends 10 hours a day outdoors, there is not much urge to look outdoors from indoors too through glass, but the building could be such that windows are on common space corridors where one could easily walk in indoor clothing.
If the building is five or ten apartments thick, there is less circumference & 3d-surface area per volume, which means less heat dissipation in heating seasons and more energy-efficiency.
Construction per volume is cheaper.
It needs less land per volume and per inhabitant compared to the normal 2 apartment thick buildings. One related upside is that nature around the building can be in bigger contiguous pieces rather than small pieces of green between buildings.
It needs multiple technological solutions to make it more palatable. Here are some:
Need lots of air pipes, so better have 1 meter of extra height with ceiling and extra-wide corridors. The pipes would be in corridors, so higher ceiling in rooms would somewhat compensate for lack of windows. Some air pipes go to sides, some to roof.
Every room with many lights all over the ceiling, and many light switches, some with color adjustment knobs with one physical wheel for every 3 color channels( red, green, blue ) Need to be able to switch on only those lamps that are not within field of view.
Every apartment could have door to 2 different corridors on opposite sides, 2 doors.
Equivalent to opening window for ventilation would be putting air pipe fans on extra speed. Direction of airflow could be decided based on wind direction outside, maybe automatically, so air flows inside along the air flow outside (but usually slower).
Backup batteries for 2 days of normal use. Maybe sodium-ion batteries.
Other technical solutions may be needed besides those mentioned here.
One version could be that some large apartments are really long and have window in only one room.
Windows are less important for hotel rooms, so hotels first. Maybe have building that has apartments with windows on the outer edge while hotel rooms are in the core.
Upside of no external wall or window is avoiding noise from cars, dogs, planes and thunder.
Upside of common space windows is 360 degree visibility on all heights, from inside the building as a whole, and especially if the building is octagon-shaped.
Everyone likes room windows, but others give it a different weight relative to other considerations. In some areas, there might be a choice between having 1000 people living in streets, 1000 people living in windowless apartments or 500 people living in windowed apartments+500 people living in streets.
Making something worse to make something else better is a tricky type of idea to argue for.
Any atrium, courtyard or lighting well inevitably increases heat flow to outside, even if covered with glass. Firstly, it is more surface area for the building. Secondly, warm air rises up and heat conducts through the roof glass much faster than through rock wool+concrete. Glass is thinner and has higher thermal conductivity than concrete or some insulation material.
In a big building, atrium is basically a dark alley, not providing enough illumination for most things, so on that alone it is questionable expense to pay for the extra walls, atrium windows, room windows etc.
Atrium or courtyard is needlessly large for ventilation. Stairwells and elevator shafts can take some of that too.
If the atmospheric air is behind a window, it means heat dissipation and the apartment is on the edge at least partially. If there is some sort of shaft / square and wide pipe / atrium vertically inside building, that means space not used as living space, regardless if it is for light and air or just for light(window covered shaft). That shaft and the windows also cost money. Also noise of planes and thunder come from there. But it is good option somewhere for some people, just like windowless apartments are good option for others.
For example, the Pentagon building with it's multiple rings does not count as donut-shaped solid, unlike the Apple building.
Atrium means choosing more construction expense, more heat transfer to outside, more noise and more walking distance to some apartments. Sometimes those are ok choices for the whole, but in my opinion, world has enough atriums already ( and overly large windows ) and energy saving should be much higher priority instead.

Hi guys! I'm training for my first 100k and i'm encountering some hydration problem that i was hoping you could help me figure out.
Every Sunday i go for a long run and at the moment i'm running around 60k and 3000m of elevation. Temperature is generally between 10C and 20C. I usually carry with me: 2 liters of isotonic solution (that i can remake at different fountains), half a liter of water, fruit jelly for fuel and a couple of almonds. The issue i encounter is always the same. Many hours into the run (6+h) i start feeling thirsty and at the same time i start peeing very frequently, to the point i feel like i can't really drink anymore despite the feeling of thirst. From here things really go south fast. I quickly stop being able to eat and start feeling confused and tired. In a couple of hours i am forced to stop completely. While the need to pee stops quite soon as i stop drinking, the feeling of thirst persist well after the run. It takes usually around 24h to go away and seems to improve ever so slightly after eating a meal. Last run i have tried supplementing with salt pills (300mg sodium per h increased to 500mg the last two h), but it didn't change much the symptoms, although it made me throw up salty water 1h after the end of the run.
The question that i have is simple. Am i dehydrated, overhydrated or in hyponatremia ? I cannot really fit my symptoms together. The thirst makes me feel like i'm dehydrated but that doesn't explain why i have to constantly pee. Hyponatremia could make sense as this issue usually kick in during the descent, when i don't sweat as much and i might be consuming to much water. However i would expect the salt pills to reduce it or at least delay it and it still doesn't fit with the fact that i am thirsty all the time.
Does anyone have any idea what is going on with me? Thanks in advance

I have been trying to find an answer to this for a while, but I can’t seem to. I have about 1L of a saturated gold chloride solution that I want to extract the gold metal from. To clarify, this is not aqua regia or a product of another reaction. Per the manufacturer, it’s simply gold chloride. I have been accumulating it from “expired” leftover solutions over the last few years and it’s become concentrated enough that there is precipitation at the bottom. I read that I can crash out the gold with sodium metabisulfate, which I tried in a well ventilated area with a small amount of the gold. All that happened as far as I could tell was that the solution went clear and (of course) made The Big Stinky SmellTM. I didn’t see anything come out of solution like it did for everyone else. Can I just evaporate the water and collect what dries out? Not sure how to proceed. Thank you in advance

The question is calculate the pH of a solution containing 500mg of naproxen sodium dissolved in 100ml of water. The pKa is 4.2 and the molecular weight of naproxen sodium is 252 g.mol.
I’ve used the following equation pH= 1/2 kw + 1/2 pKa + 1/2 log( Co) this calculation gave me an answer of 8.25 for the pH, however I’m not sure that this is correct as it does not take into account the 100ml of water. Is this answer only correct for 1ml of water or also for 100ml of water? If not how would I incorporate the 100ml to calculate the correct pH.

• Species: Canine (dog) • Age: 4 y.o. • Sex/Neuter status: neutered • Breed: Labrador retrieveChesapeake Bay retriever • Body weight: 80 lbs • History: healthy- no major issues • Clinical signs: uveal mass w/cystic component • Duration: first noticed March 25th, 2024 • Your general location: Colorado, USA
On March 25th I noticed a red “bubble” in my dog’s eye (inside the eyeball). I monitored for a few days and there was no change; he wasn’t showing any signs of pain/discomfort but it didn’t go away. I made a vet appointment on 3/29/24 with our primary vet. The primary vet initially thought it was a hematoma from potentially hitting his head or playing too rough. He ran a glaucoma test, ulcer test, checked for abrasions, and did blood work (all came back normal). He prescribed dexamethasone sodium phosphate eyedrops to administer 3x per day for 1 week. We followed up with our primary vet on 4/5/24, there was no change after using the drops for 1 week. At this point he referred us to an animal ophthalmologist. We scheduled the appointment for 4/26/24 (that was the earliest option they had).
On 4/20/24 he showed signs of pain/discomfort so we decided to bring him into the emergency vet. They redid the glaucoma test, ulcer test, and checked for abrasions (all normal). They virtually consulted with an ophthalmologist (sending photos and test results). This ophthalmologist diagnosed it as a uveal mass and recommended enucleation. They sent him home with carprofen 100mg 1x/day, gabapentin 200mg 2x/day, and neo/poly/dex ophthalmic solution 2x/day.
On Monday 4/22/24 we called the ophthalmologist office we had our original appointment scheduled with for 4/26/24. We asked to be seen earlier for a second opinion on the uveal mass diagnosis from the emergency vet. They got us in on 4/22; in which they repeated the tonometry test, fluorescein stain, and also did a schirmer tear test. All were negative/normal. The ophthalmologist did an exam of his eye with different scopes and agreed with the diagnosis of uveal mass; however he said there’s a cystic component as well. Below are the results of all the diagnostic tests they ran:
Schirmer Tear Test - Initial: 27 mm/30s 22 mm/30s Fluorescen Stain - Initial: Negative Negative Tono Vet Rebound Tonometry-Initial: 3 mmHg 12 mmHg Menace Response: Good Good Dazzle Reflex: Good Good Pupillary Light Reflex (PLR): Normal Normal Biomicroscopy: Abnormal Normal Binocular Indirect Ophth.: NSF Normal
He recommended enucleation with biopsy of the mass. He said the mass wouldn’t be surgically resectable which is why the full removal is necessary.
We have scheduled his surgery for the end of this week. I’m mostly just feeling guilty and nervous that he’s so young. I am happy we got the second opinion and I trust the vet teams; I just want to be sure that this is the right course of treatment for my boy.
I tried to link the photos in the comment below. I haven’t ever done that before so I apologize if it’s not the right way.
Thank you all!

Im doing some brass etching for the first time and I need some help

1. remove protective layer on one side and apply to brass sheet
2. put a piece of paper on top of brass sheet
3. laminate using an iron
4. put transparent paper on top of resist and expose to uv light for 3:30
5. remove second protective layer
6. drop in solution to dissolve uncured resist

I've tried washing soda and sodium carbonate and neither solutions have managed to dissolve the uncured resist.
The ratio i used: 5 grams of Sodium carbonate to 500ml of water or 5 grams of washing soda to 1L of water
Why is it not dissolving? Is it because my exposure time is too long? Am I using too much heat?
Edit: I figured it out! The issue was with the black ink on my transparent paper—it wasn't dark enough. Consequently, the UV light managed to pass through, causing everything to harden. The difference might not be immediately noticeable since the supposed "unexposed" part retains a light blue hue compared to the exposed area, which is a dark blue.
I hope this is useful for that one person in the future that ends up with the same problem lul.

Hey, i recently modded a server and the server doesnt allow sodium/optifine or the Client just crashes. Do you guys maybe have a solution for this issue?
If it`s necessary to delete some mods please name them.
Thanks.
(Modpack in Comments)

I need to surface sterilize S. lateralis ootheca and raise them germ-free for an experiment. The issue I'm having is that the paper I'm using as a guide doesn't provide the ratio for the enzymatic lysis buffer solution for the final wash before rinsing the ootheca. I have all the ingredients for the solution in my lab, just don't know the concentration.
Here is an excerpt from the paper (Jahnes et al., 2019): "Ootheca were manually detached from gravid P. americana females and surface sterilized by three rounds of cleaning using a detergent scrub (1% Alconox detergent), dilute bleach (0.08% sodium hypochlorite), and then an enzymatic lysis buffer (lysozyme 10 mg/ml, EDTA, Tris-HCl and Triton X-100), each step followed by three rinses with sterile MilliQ water (MQW) to remove antiseptic solution and induce intermittent hypo-osmotic shock on surface-clinging bacteria (Schwinghamer, 1980; Salema et al., 1982)."
Does anyone have any suggestions for that enzymatic lysis buffer (ingredient concentrations)?
Thanks!
(Edit: I don't think the enzymatic lysis buffer step is necessary, this paper was the first to my knowledge to do it - but it would still be cool to know :)

Recently I have been seeing a lot of posts about getting stuck at X weight, or “I cheated and now I am out of Ketosis.” So I wanted to share my journey with you and what has helped me go from where I was, 343 lbs at my heaviest, down to 280lbs as of this week the last time I weighed myself. Today I am lighter than I have been in over 15 years! I still have a long way to go, and my end goal is 200 lbs, because I want to be thin and attractive and I want people to respect me and not judge me because I am fat, just like you probably reading this right now. Well, I am here to try and help!
My journey started with an initial health scare from when I visited the doctor back in 2019, as you are all probably aware of, pre-diabetic, stage 3 fatty liver, ect… I had known about Keto diets in the past, when I was younger, the low carb diet at the time was Atkins, and I had used this diet before to keep my weight in check as I have always struggled with my weight, but that was back in my early 20s. My solution to fixing my health problems (and weight problem) was to go back on a ketogenic diet.
In 2019, I went through the struggle of getting my body in ketosis, dealt with keto flu, low energy, and was able to overcome those challenges and get on a good track of staying low carb. I managed to do this for about a year before I started to slip. It started with small slip ups here and there “a few Doritos wont hurt, its just a hand full.” “A small piece of cookie wont hurt.” Before I knew it (mid 2022), I was kicked out of Ketosis and craving high carb foods again and back into old eating habits. I went from 343 down to 283 then back up to 312 lbs, Darn! I was losing the battle...
Then in 2023, I started having health issues again, which I won’t go into details, and I wanted to get my health in check for good. What was needed, in my opinion, was a fundamental shift in the way I (we) view food. We need to look at food as an essential building block and an energy source for our body and get out of the mindset of looking at food for comfort and enjoyment. This is not an easy thing to do and is probably the hardest thing I have ever done next to getting an Engineering Degree, but if you can master this one thing, you will be hugely successful in your journey to losing the weight and being healthy.
Step 1: Small steps and Logging
My first piece of advice is start small. Yes, you are impatient and yes you want to be thin RIGHT NOW! I get it, but this won’t happen overnight. This is a long process that takes a long time. You are fighting an uphill battle. You are probably surrounded by people eating all kinds of high carb foods, you probably got that skinny friend/relative that can eat anything and stay thin (NOT FAIR! I totally get it..). The first thing I recommend is track absolutely everything you eat. Lose it is only $3 bucks/month (best money I ever spent). Do not try and diet yet, just track what you are eating. Eat a cookie? Log it! Eat an entire party bag potato chips? Hey don’t sweat it! But LOG IT! Get into the habit of logging absolutely everything you put into your body no matter what it is, and don’t judge yourself for your bad eating habits, don’t worry you and me, we are going to fix this together!
After about a week (maybe 2 weeks), make a small change… I was eating about 250 net grams of carbs per day, so I set a reasonable goal for the next week… Lets see if I can get that down to 150 net/day for a week. One week goes by, easily beat it! All it took was cutting some bread out of my diet as well as rice and potatoes. Next step, 100 net/day. Weeks goes by I was at 120 net/day. Darn! I tried my best, but next week, I’m going to do it! Next week goes by I was at 99 net/day. Yes! I did it I hit my goal. Let’s see if I can do it again and again. 2 more weeks go by, and I was down to 80 net/day without hardly trying. Then I lowered my goal to 50/day and that is when it started to get hard. Now I had to cut that slice of toast out of my diet with my morning eggs. I had to cut that bowl of rice out with my meat. I had to really start making some hard changes, and I wasn’t always successful during the first month. I went over and hit 60/day, but I kept at it, kept logging. Today I average 21 Net/day carbs (not too bad right). The best part about the second time I got myself into Ketosis, there was ZERO side effects. No keto flu. I did have electrolyte imbalances for a while but was easily fixed with upping potassium and adding more salt to my food.
The key here is set reasonable goals for yourself that you know you can beat, you wont always be successful, but keep at it. Breaking bad habits is hard, but if you keep logging, and you keep at your goals, eventually you will break it!
Step 2: Eat only nutrient dense foods
This goes back to looking at food as building blocks and energy for your body, make sure every food you eat is to fulfil a specific nutrient requirement. You need more potassium, eat more kale/spinach, need to get your vitamin D up, eat some smoked salmon. Over time, your taste buds will change, and you will start really enjoying the foods you are eating. I absolutely LOVE kale now!
Also, this includes keto-friendly foods like bacon. I do not eat bacon. There is almost no nutritional value in eating it, so why eat it? Eat some steak instead.
If I eat a food with Carbs, it will be a very nutrient dense food and because my body needs those nutrients. What kind of foods am I talking about? Here are some examples:
73% + or more cocoa chocolate
Berries (strawberries for example)
Lemons/limes
Nuts and seeds of all kinds.
All kinds of vegetables like broccoli, spinach, kale, Peppers, Onions
The Key to staying in ketosis when you are consuming foods with carbs is moderation. Yes that 70% chocolate has sugar in it, but I eat one square MAX per day. That one piece of chocolate has 4.7 grams of net carbs and 2 grams of fiber. There is plenty of room in my daily carb limit to allow for it. As long as my weekly average total carb intake stays under 25 grams/day, I am good (my personal set goal).
Step 3: NO CHEAT DAYS!!!
Once you are in the groove, and you got your carb intake to your set goals, be EXTREMELY strict with food intake. Allow for ZERO cheat days and have a ZERO tolerance policy on any "empty carb" food. What do I mean by empty carb? any food that is high in carbs and has no nutritional value, like cookies, chips, ice-cream ect... Cheating will get you kicked out of ketosis and is the path back to bad eating habits and putting the weight back on and that is exactly what happened to me! Just don’t do it. We are not eating for comfort anymore; we are eating because our bodies need this specific nutrient. This is the goal.
Step 4: Fasting
You don’t need to do this right away, make sure you get yourself into the habit of logging, and eating foods that are nutrient dense and make sure your body is in ketosis first. Like with before, don’t try and jump headfirst into fasting, take small steps and build on it every week. Start with a shorter duration fast once per week, for 12 hours, then increase slowly until you hit 18 hours. The end goal here is twice per week for a minimum of 18 hours. If you get hungry and you cant do it, don’t beat yourself up over it, its hard! Your body will fight you and want you to eat. Try again the next week with your set goals. Just make sure you are eating those nutrient dense foods we talked about above. As your body becomes more and more fat adapted, this will get easier and easier.
I am currently fasting for 24 hours on Mondays and Tuesdays. Monday morning I eat 2 fried eggs and drink my coffee with half and half then fast until Tuesday morning. Then on Tuesday morning, I will eat 2 fried eggs and that same coffee without eating until Wednesday morning. It is currently Tuesday and I have not eaten since this morning. I won’t eat until tomorrow morning.
To prep your body for long fasts that will allow your body to eat itself with ease is making sure you are LOADED with TONS of nutrients, (remember step 2?). Saturday and Sunday are prep days for that fast. I eat dark leafy greens, like Kale, and Spinach, cheesy broccoli I make myself, peppers, ect... I eat lots of nuts and seeds, Walnuts, pecans, brazil nuts, peanut butter, steak, Smoked raw salmon. I will eat a little bit more than my metabolic rate, about 200 calories more (2500 cal). I also generously salt everything so that I am around 4000 MG for the day. This will load your body with potassium, magnesium, and sodium. Then I go into my fast on Monday. Perfect for me since I need to be at work on Monday and Tuesday.
If you do this, when you go into your fast, you will have plenty of nutrients/electrolytes for your body to just eat your own fat off your body. You probably wont even feel hungry for many hours on end, but if you do get hungry, drink lemon in water, or apple cider vinegar to suppress your hunger.
Now, the key to coming out of your fast is to NOT over-eat. Eat VERY SLOWLY (I cannot emphasize this enough). Take bites, chew, put your fork down, wait 10-30 seconds after you swallow, then take another bite. Eat high fat foods like cheese, eggs, peanut butter. This will help you feel satiated. Try and keep your first meal out of a fast at around 1000 calories.
Step 5: Exercise
Try and add exercise into your weekly routine and this will help you lose the weight even faster, but is not necessary to lose the weight. Exercise is really good for you anyway. For me personally, I picked up swimming (I swim 2 miles 3x per week now), and I feel great afterwards, all those endorphins! So why not?
Step 6: For life!
What do I mean for life? What I mean is that you need to view keto as a for life plan. The key to staying healthy is eating healthy. So why ever go back to your old way of eating? On this diet, I feel great, my libido is way up and I have tons of energy to do things! I want to go outside and work on my car! I want to go to the gym. When you are eating healthy, you will feel amazing, you will have moments of euphoria, you will be happy, you will have an amazing sex life! That guy/girl you like at the gym will notice you. You will no longer be ignored! You will also be smarter, your mental clarity will be better than ever, you will be able to focus on your goals!
Final piece of advice: You will fail… yes you will fail at your goals over and over again, I still fail my goals once in a while. Last week I had a day where I went up to 30 net/day carbs and ate 2600 calories (DARN!), but I didn’t give up! I wont give up! Sometimes you will slip, but as long as you set reasonable goals for yourself and tighten those goals solely over time, and you keep at it, you will be successful in the long run, and you will get the weight off! Don’t focus on the scale, but focus on getting into healthy eating habits, focus on exercising and I promise you, the weight will come off!

Hey all, Having a lil issue with persistent Cu(I) salts in my org compound after a CuAAC reaction. Reaction is in t-BuOH/water (1/1) 8.4 mL. Tryna figure out a good workup protocol to remove the Cu(I) salts from my product, this is what's currently planned:

1. Quench reaction in separate rbf in sat.NH4Cl solution / DCM until blue colour appears Extract Aq 2x DCM
2. Wash with NaHCO3, brine
3. Dry w/ sodium sulphate
4. Concentrate
5. Column

I've done some searching and seen NH4OH aq used and also sodium DCC. I'd really appreciate if anyone had any post CuAAC workups or good wash procedures for Cu(I) salts.
Thanks in advance :))

Taking Ortho-K out and it feels like there is something in my eye. I am a 21 year old female. I am 5’7 and I weigh 125 pounds.
I have been wearing ortho-K for 12 years and I’ve never had a problem with my contacts until this past April and it is continuing into May. In April, I had an eye infection in my right eye and my eye doctor gave me Bausch+Lomb Neomycin and Polymycin B Sulfates and Dexamethasone Ophthalmic Ointment. I placed a peppercorn sized amount of ointment in the bottom of my right eye where the eye is attached to the eyelid every night before I went to sleep for 5 days as instructed by my optometrist.
After 5 days I tried to wear my ortho-K contacts again but I kept waking up very early in the morning due to irritation and I had to take the ortho-K lens out. I called my optometrist to see what the problem was and she said to use the ointment for a few more days so I stopped the ortho-K and used the ointment again.
I went to see another optometrist who checked my eyes and she said there was nothing wrong with my eye (I assume the infection was gone at that point) and there was nothing wrong with my contact. So I started to wear my contacts again. I make sure to use eye drops in my eyes prior to putting the contact on and I drop some in the lens before I put it in my eye. Before I remove it, I drop an eye drop in my eye too and move it around to loosen it up. The same problem occurred, I had to get up very early to take my contacts off due to irritation.
I made another appointment to see a third optometrist and he did many tests and looked at my eyes and contacts and he was not able to find anything wrong either. He said that there was no eye infection and that the contact was not cracked. This was the appointment summary “Patient is having discomfort with OOK lens OD- inspected new and old lenses and no chips or cracks in the lenses. Reviewed lens care and hygiene. May have some protein in reverse curve. Will run through Progent and also gave new ClearCare case/solution. Educated that lids are tighter and may be getting a GPC reaction. Will try to resume lenses and RTC if returns.”
I went to this appointment yesterday on 5/13. I wore my contacts the same night after using Progent for 30 minutes and I left the contacts in the ClearCare solution for 12 hours prior to wear. This morning on 5/14 I did not wake up due to irritation of the contact but when I took my contact out it feels like there is something stuck in my eye (the same feeling I had when there was an infection in my eye but the optometrist said that there was nothing in my eye.
I don’t know what to do now. I have seen multiple optometrists and they were not able to find anything wrong with my eye. The optometrist I saw yesterday also said that there was nothing wrong with the fit of the ortho-K contact lens too. Is it just because my eyes are dry or is there another underlying issue. Thank you to whoever reads this and might have a solution. Please feel free to ask any questions regarding my problem so you can help me assess what’s wrong.
TLDR: I have been wearing ortho k for 12 years. This past month I have had irritation in my right eye where I am woken up from my sleep to take it out and when I take it out it feels like there is something in my eye.

I have been wearing ortho-K for 12 years and I’ve never had a problem with my contacts until this past April and it is continuing into May. In April, I had an eye infection in my right eye and my eye doctor gave me Bausch+Lomb Neomycin and Polymycin B Sulfates and Dexamethasone Ophthalmic Ointment. I placed a peppercorn sized amount of ointment in the bottom of my right eye where the eye is attached to the eyelid every night before I went to sleep for 5 days as instructed by my optometrist.
After 5 days I tried to wear my ortho-K contacts again but I kept waking up very early in the morning due to irritation and I had to take the ortho-K lens out. I called my optometrist to see what the problem was and she said to use the ointment for a few more days so I stopped the ortho-K and used the ointment again.
I went to see another optometrist who checked my eyes and she said there was nothing wrong with my eye (I assume the infection was gone at that point) and there was nothing wrong with my contact. So I started to wear my contacts again. I make sure to use eye drops in my eyes prior to putting the contact on and I drop some in the lens before I put it in my eye. Before I remove it, I drop an eye drop in my eye too and move it around to loosen it up. The same problem occurred, I had to get up very early to take my contacts off due to irritation.
I made another appointment to see a third optometrist and he did many tests and looked at my eyes and contacts and he was not able to find anything wrong either. He said that there was no eye infection and that the contact was not cracked. This was the appointment summary “Patient is having discomfort with OOK lens OD- inspected new and old lenses and no chips or cracks in the lenses. Reviewed lens care and hygiene. May have some protein in reverse curve. Will run through Progent and also gave new ClearCare case/solution. Educated that lids are tighter and may be getting a GPC reaction. Will try to resume lenses and RTC if returns.”
I went to this appointment yesterday on 5/13. I wore my contacts the same night after using Progent for 30 minutes and I left the contacts in the ClearCare solution for 12 hours prior to wear. This morning on 5/14 I did not wake up due to irritation of the contact but when I took my contact out it feels like there is something stuck in my eye (the same feeling I had when there was an infection in my eye but the optometrist said that there was nothing in my eye.
I don’t know what to do now. I have seen multiple optometrists and they were not able to find anything wrong with my eye. The optometrist I saw yesterday also said that there was nothing wrong with the fit of the ortho-K contact lens too. Is it just because my eyes are dry or is there another underlying issue. Thank you to whoever reads this and might have a solution. Please feel free to ask any questions regarding my problem so you can help me assess what’s wrong.
TLDR: I have been wearing ortho k for 12 years. This past month I have had irritation in my right eye where I am woken up from my sleep to take it out and when I take it out it feels like there is something in my eye.