Bactrim ds sulfamethoxazole trimethoprim

Has anyone else experienced this or have any advice? My stomach hurts so much after taking a week of Sulfamethoxazole TMP DS after getting my abscess drained. It’s not a sharp pain but it burns almost constantly. It gets especially bad at night and I can barely sleep. I definitely had some kind of IBS/gluten intolerance before that I learned to manage but this is on a whole nother level of discomfort. Obviously I’m guessing my gut microbiome has been obliterated and have been trying to eat well/not drink etc. but nothing seems to be helping it. Going to try to find a GI specialist and maybe call my CRS about it. I have surgery scheduled for next month for what appears to be a simple fistula.

Hi,
My symptoms started in January, 1 week after finishing a round of metronidazole. (for SIBO) I had to urinate frequently, and had a strange sensation in my urethra. The urologist first prescribed Sumetrolim (sulfamethoxazole, trimethoprim) for suspected UTI. The frequent urinating symptom got better, but I still had that strange feeling in my urethra. Hard to describe, but it seems like one drop of urine always stays in the urethra and that gives this strange feeling. Then another doctor prescribed Doxycyclin, as he suspected that my issues are caused by “atypical bacterias”. It didn’t really help, so I went to a third urologist, who ordered an STD test and urine culture. Both came back negative. Ultrasound and blood work also did not show any anomaly, so he diagnosed with non-bacterial chronic prostatitis and recommended Proxelan cone and Kegels exercises. I’m taking this for one month already, and sometimes I feel like it’s gone and I’m fine for a few days, but then it comes back. I often feel perineal pressure / tension, and I have frequent urination. By frequent I mean I have to go to the bathroom every 30 minutes, and this happens in the late afternoon hours and lasts for 2-3 hours, then it’s better again. I don’t have any pain apart from that, so I’m not sure if I really have CPPS or not. It’s also strange that this frequent urge to urinate starts around 16:00 every day. (and sometimes it does not happen for days, and then it appears again)
Did any of you experienced something similar?

Is a bowl of cereal and the like okay to have right before taking this medication?

Is a bowl of cereal and the like okay to have right before taking this medication?

My son, 13M/AFAB, 5'2", 146lb 14.4 oz, mixed white and First Nations, the primary complaint is over the last 7 weeks he has had a combination of dizziness, nausea, headaches, back pain, off/on low-grade fevers, rash for and others. Previous DX- GAD, ADD, Presumptive Autism. I am attaching a link to all of his current labs, PHI redacted, and will be copying and pasting from the post I made in /rdiagnoseme which directed me here for more fine-tuned advice. I will try to combine my responses in this post though to help. Also, we are currently working with his Pedi and have referrals and appointments end of May and in June for Hem/Onc, Infectious Disease, and Allergy Immunology at the children's hospital in our state.
From the post body- "I'm at a loss regarding what could be happening and feel like I'm in a bad episode of House, but with my 13-year-old, and there is no quirky doctor helping us out on the sidelines. Before I delve into everything that has happened and the symptoms present/past, I want to clarify that we are working closely with his pediatrician and have referrals to see pediatric specialists in Hematology/Oncology, Infectious Disease, and Allergy/Immunology. However, there hasn't been a clear direction regarding the underlying issue, so I am really seeking any additional tests or areas for investigation that I can discuss with his Pediatrician. This has been ongoing for the last 7 weeks now, and both he and I are feeling frustrated and exhausted, he's managed 1-3 days a week of school. Any insights or suggestions would be greatly appreciated.
Current Medications:
Hydroxyzine 15mg oral suspension
Tylenol
Supprelin LA
Previous Medications (Prior to 3/8/24):
Hydroxyzine 15mg oral suspension
Draytana patch 15mg
Prozac 10mg (for 3 days)
Tylenol and Advil
Supprelin LA
Timeline of Events:
End of February: Everyone in the household had a brief cold, which resolved without fevers or down time.
March 4-8: My son began experiencing stomach pain, culminating in a trip to the ER on March 8 due to intense pain resembling appendicitis. A CAT scan revealed all organs to be unremarkable and fine, but several swollen lymph nodes were detected in his lower abdomen. These lymph nodes appeared to be the source of the pain while awaiting blood work. Given the discovery of low platelet levels, we were advised to discontinue most medications and repeat the labs.
March 9-27:Multiple blood tests were conducted, and the pediatrician began making referrals. However, the specialists did not agree with the pediatrician that it warranted a more urgent and quick appointment time. During this period, we experienced increasing nausea, dizziness, reduced appetite, headaches, joint pain, and back pain, but no fevers.
March 28:He reported feeling nauseous and expressed a desire for soup for dinner but was unable to maintain an appetite. His older siblings called me, informing me that he was shaking. I took his temperature, and it was 102.8°F. I immediately called the after-hours number to inquire whether I should treat him with APAP at home or bring him in. While waiting for a call back, I checked his temperature again after about 30 minutes, and it had risen to 103.6°F. Deciding to take him in, I administered 460mg of APAP. Upon arrival at the ER, his temperature had reached 104.1°F. It required three bags of saline, an additional dose of Tylenol after reaching the maximum dosage, and 4.5 hours for his fever to decrease to 100.6°F before they discharged us. The medical team also conducted a myriad of tests.
March 29-Present:Continued symptoms of dizziness, nausea, occasional low-grade fevers, and a transient rash on his extremities have persisted, further complicating the diagnostic process.
TLDR:
13yo, multiple symptoms listed below, and bloodwork data attached, referrals and appointments with hem/Onc, allergy/immunology, and infectious disease pending.
Symptoms/Findings:
Stomach pain
Nausea
Dizziness
Reduced appetite
Headaches
Joint pain
Back pain
Shaking or tremors
Fever (with varying degrees)
Fatigue
Rash (blotchy, sore, itchy, raised sandpaper-like)/Blanched when touched lasted aprx 7 days
Low platelet levels/ITP
Attention deficit disorder (ADD)
Generalized anxiety disorder (GAD)
Constipation
Eosinophilia"
I also realized he had two IgGs done that I somehow didn't download which were end of March and 4/17 both totaling over 5000.
We are in the PNW and haven't traveled out of our state in the past 4 years, but did go to the reservation in Canada around 6 years ago. He is able to go to school 1-3x a week but typically the next day is so worn out he doesn't have the energy to go again in addition to going to school mid-day not early morning.
Based on the UA results I requested that we do a course of antibiotics, even though not all markers are present, it has been the one constant thing. This is the message I sent to his pediatrician-
"I'd like to see if treating [son's name] for a bacterial UTI relieves some of his symptoms he is having now that a moderate amount of bacteria is present with leukocytes, WBC, RBC, and Mucus present in this latest test.
His platelets are now 121, while still low, a much more comfortable amount in regards to bleeding protocols and concerns.
Diving into several common treatments that are used in pediatric UTI, the antibiotic trimethoprim/sulfamethoxazole is a favorable choice and per a NIH study and several others the instances of drug induced ITP from that antibiotic specifically, when given in the usual dosage is more uncommon. It also comes in an oral suspension so [son's name] sensory issues with large pills wouldn't be a concern.
Thanks again for all you're doing for [son's name]."
I got told no because he doesn't feel like the results indicate a UTI. Honestly, this is what made me start questioning more things, and I began researching more which is how I stumbled upon reddit. I've worked in clinical mental health for over a decade and just recently swapped to non-clinical so while I'm not versed in medicine I am familiar enough to navigate through and collaborate with physicians which until this point hasn't been an issue.
For the initial post getting all the information together in one spot and looking holistically and logically vs parentally really made me understand more why we are getting sent to the three specialists we are BUT it also led me to messaging last night requesting more labwork to assist in the eventual diagnosis that will happen.
So in addition to repeating CBC/CMP/BMP/UA I asked for these-
Iron Metabolism:
Serum Iron
Total Iron-Binding Capacity (TIBC)
Ferritin Levels
Vitamins and Minerals:
Vitamin B12 Level
Folate Level
Vitamin D
Magnesium
Thyroid Function:
Thyroid-Stimulating Hormone (TSH)
Free Thyroxine (FT4)
Triiodothyronine (T3)
Thyroid Antibodies
rt3
TBG
Thyroglobulin
Inflammatory Markers:
C-reactive Protein (CRP)
Erythrocyte Sedimentation Rate (ESR)
Autoimmune Markers:
Antinuclear Antibodies (ANA)
Rheumatoid Factor (RF)
Anti-double-stranded DNA (anti-dsDNA)
Anti-cyclic Citrullinated Peptide (anti-CCP)
Anti-tissue transglutaminase (anti-tTG)
Coagulation Studies:
Prothrombin Time (PT)
Activated Partial Thromboplastin Time (aPTT)
Fibrinogen Level
Immunoglobulins:
IgG subclasses
IgA
IgM
Total IgE
Serological Tests:
Helicobacter pylori
Epstein-Barr virus (EBV)
Cytomegalovirus (CMV)
Serum Protein Analysis:
Serum Protein Electrophoresis
Last but not least the lab work: https://acrobat.adobe.com/id/urn:aaid:sc:VA6C2:b21fc4c0-7bb3-4205-9640-2c09190920b6
Any insight or thoughts would be extremely welcomed!

URL: https://pubs.rsc.org/en/content/articlelanding/2021/ay/d1ay01391b
DOI: 10.1039/D1AY01391B

Hello, my students are doing an antibiotic resistance lab with non pathogenic E. coli. The sensi-discs being used are Bacitracin, Penicillin, Sulfamethoxazole Trimethoprim, and control paper. Many are seeing a change around the control paper disc where the streaked colonies become puffy and opaque white. Does anyone know why this might be happening?

Hi all,
Tomorrow i have an appointment with my eye doctor and i wanted to ask you guys what my options are cuz I'm kind of lost and absolutely don't know what to do at the moment.
Since December 2022, I've been experiencing significant issues with my left eye. The main complaints are:

• Dry eyes (both eyes)
  
• Double vision (only in the left eye)
  
• Blurry vision (only in the left eye)
  

- Frequently swollen upper eyelid (only in the left eye, it’s very asymmetrical as you can see)
I've had many appointments at eye clinics/hospitals. My last appointment was on April 11th and I was told that I need to use eye drops more frequently and that I should come back for photos in six months. I couldn’t wait that long, so i made another appointment for tomorrow. I really can't continue to live with these symptoms any longer. I've stopped attending school because I was getting headaches from the double vision. But i want to know what else can they do, i have a feeling they will just tell me to use my eyedrops more, like my last appointment, and send me away. I need all the info i can get. Please.
The only thing that has helped are eye ointments. Once at the eye clinic, I was given an eye ointment (HYDROCORTISONE/OXYTETRACYCLINE/POLYMYXIN B EYE OINTMENT 3.5G) that I could use for two weeks. After stopping, I was symptom-free for about four weeks. Then all my symptoms gradually returned. The same situation occurred at the hospital. I was given an eye ointment (OFLOXACIN EYE OINTMENT 3MG/G TUBE 3G) to use for two weeks. It worked well for four weeks, but then all my symptoms returned.
Could someone please review my results (it’s long i’m so sorry i have no idea which parts are important so i copy pasted then all) and provide tips on my next steps and whether there's anything I can do at all? I don’t understand anything from the reports.
I put all the reports in chronological order:
Treatment report from the ophthalmology:
December 19, 2023:
ICC outpatient / referral (Rheumatology): Low tear production with significant sicca and dry mouth, indications for Sjogren's syndrome? We would appreciate your analysis.
Stop Trafloxal.
Hylan 4-6 times daily once a day in each eye.
----
Treatment report from the ophthalmology:
December 19, 2023:
Conclusion
Prominent corneal nerves with pannus, extensive differentials, keratoconus?
Differentials:
-Keratoconus
-Fuchs
-Posterior polymorphous corneal dystrophy
-Acanthamoeba
-HSV/VZV
-MEN 2A/MEN 2B/MNS
-Refsum disease
-Riley-Day syndrome
-NF-1
-Leprosy
-Lipoid proteinosis
-Ichthyosis
Plan
Trafloxal once daily in the left eye
Hylan as needed
Follow-up appointment, Obtain OLCD data
Follow-up appointment: 3 weeks, check-up 3-4 weeks preferably on Tuesday morning
With corneal topography
----
Microbiological results:
December 20, 2023
1^st report:
Material: Eye
Collected on: -
Antibiotic therapy:
Clinical data: Antibiotic use: none
Question: Routine eye culture
Routine eye culture
Culture
1 Staphylococcus aureus slight
Conclusion
No anaerobic microorganisms cultured
Sensitivity
1
R Penicillin
S Flucloxacillin
R Amoxicillin
S Amoxicillin+Clavulanic acid
S Gentamicin
S Tobramycin
S Vancomycin
S Ciprofloxacin
S Erythromycin
S Clindamycin
S Doxycycline
S Trimethoprim/Sulfamethoxazole (co-trimoxazole)
S Mupirocin
S Fusidic acid
S Rifampicin
S Chloramphenicol
Explanation of sensitivities:
S = sensitive, I = intermediate / reduced sensitivity, R = resistant
2^nd report:
Material: Eye
Collected on: -
Clinical data: Antibiotic use: none
EXAMINATION RESULT UNIT INTERPRETATION
-----------------------------------------------------------------------------------
Adenovirus PCR No DNA detected
C. trachomatis No DNA detected
N. gonorrhoeae No DNA detected
Herpes simplex virus 1 PCR No DNA detected
Herpes simplex virus 2 PCR No DNA detected
Varicella zoster virus PCR No DNA detected
The test method is not validated for this body material.
3^rd report:
Material: Eye
Collected on: -
Clinical data: Antibiotic use: none
EXAMINATION RESULT UNIT INTERPRETATION
-----------------------------------------------------------------------------------
Acanthamoeba species PCR *
----
Letter to my GP from the ophthalmology:
December 20, 2023:
Dear colleague,
The above-mentioned patient was seen by us on December 20, 2023, at the Ophthalmology Outpatient Clinic.
Reason for visit / Referral
For a few months, the patient has been experiencing problems with her left eye. She experiences blurriness, has difficulty reading texts, her eye tears a lot, and she struggles with focusing.
Conclusion
Visible corneal nerves with pannus, past inflammation? Other pathologies?
Plan
Trafloxal once daily in the left eye
Hylan as needed
Follow-up appointment, Obtain OLCD data
Follow-up appointment: 3 weeks, check-up 3-4 weeks preferably on Tuesday morning
Requested investigations
Functional examination: OCT
Medical microbiology, eye, eye: Eye routine culture, Eye adenovirus PCR, Eye C. trachomatis/N. gonorrhoeae PCR, Eye Herpes/Varicella PCR, Eye Acanthamoeba PCR (December 20, 2023)
Medical history
For a year, the patient has experienced blurry vision and sicca symptoms, especially in the left eye. Often feels inflammation. Sees images separating, causing double vision. Often blinks. Visited -, received treatment for dry eyes and Hypromellose.
Artificial tears provide relief for sicca symptoms, but blurry/double vision in the left eye persists. Current glasses are 3 years old.
Last wore contact lenses 3 years ago, these symptoms have been present for a year.
Ocular history: -
Family ocular history: -
Relevant medical history:
Medication as per referral
Physical examination
Visual acuity with own correction OD: 1.0= S -1.75 C -1.00 axis 8
Visual acuity with own correction OS: 0.4- S -2.00 C -0.75 axis 1
Visual acuity after refraction OD: 1.0= S -1.50 C -0.75 axis 5
Visual acuity after refraction OS: ntv S 0.00 C -2.00 axis 135
Remarks on visual acuity OS: AR irregular rings and highly variable AR values

Autorefraction
Measurement method / remark: AR for cyclo.
1.0= S -1.75 C -0.75 axis 15
< 0.4- S -0.75 C -2.00 axis 150
Measurement method / remark: AR after cyclo.
S -1.00 C -0.25 axis 5
S 0.00 C -2.00 axis 135
Tonometer OD: 12 mmHg, applanation.
Tonometer OS: 12 mmHg, applanation.
Slit lamp examination OD: clear cornea, mild punctata, clean/deep anterior chamber, clear media
Slit lamp examination OS: Conjunctival hyperemia+, cornea confluent punctata centrally diffuse, visible corneal nerves, deep/clean anterior chamber, clear media
Fundus OD: pink and sharply demarcated optic discs, beautiful maculae, and no abnormalities peripherally OD
Remarks: Everting gb, inferior fornix papillae with numerous calcareous concretions
Additional investigations
OCT macula OD: no abnormalities
OCT macula OS: no abnormalities
Schirmer test: OD 7 mm and OS 3 mm (after 5 minutes with oxy)
----
Treatment report from the ophthalmology:
January 9, 2024:
Conclusion
Calmer picture, sicca with very low tear production in both eyes and complaints of dry mouth
No visible corneal nerves
Regular astigmatism in the left eye, differential diagnosis of forme fruste keratoconus
Plan
Follow-up appointment: 3 months, check-up with Bauke corneal topography, in conjunction with Dr. B
----
Treatment report from the ophthalmology:
April 11, 2024:
Conclusion
Sicca keratitis in both eyes
Plan
Follow-up appointment: 6 months, Repeat corneal topography for Mr. -
Increase Artelac to 6-8 times daily in both eyes
----
Gender: Female
Age: 28
Height: 177cm
Weight: 74kg

Hi all,
So I'm kind of lost and absolutely don't know what to do, and I hope you guys can help me out with my options and next steps.
Since December 2022, I've been experiencing significant issues with my left eye. The main complaints are:

• Dry eyes (both eyes)
  
• Double vision (only in the left eye)
  
• Blurry vision (only in the left eye)
  
• Frequently swollen upper eyelid (only in the left eye)
  

I've had many appointments at eye clinics/hospitals. My last appointment was this past Thursday, and I was told that I need to use eye drops more frequently and that I should come back for photos in six months. I can't wait that long. I really can't continue to live with these symptoms any longer. I've stopped attending school because I was getting headaches from the double vision. I really can't endure this for another six months.
The only thing that has helped are eye ointments. Once at the eye clinic, I was given an eye ointment (HYDROCORTISONE/OXYTETRACYCLINE/POLYMYXIN B EYE OINTMENT 3.5G) that I could use for two weeks. After stopping, I was symptom-free for about four weeks. Then all my symptoms gradually returned. The same situation occurred at the hospital. I was given an eye ointment (OFLOXACIN EYE OINTMENT 3MG/G TUBE 3G) to use for two weeks. It worked well for four weeks, but then all my symptoms returned.
Could someone please review my results and provide tips on my next steps and whether there's anything I can do at all? I don’t understand anything from the reports.
I put all the reports in chronological order:
Treatment report from the ophthalmology:
December 19, 2023:
ICC outpatient / referral (Rheumatology): Low tear production with significant sicca and dry mouth, indications for Sjogren's syndrome? We would appreciate your analysis.
Stop Trafloxal.
Hylan 4-6 times daily once a day in each eye.
----
Treatment report from the ophthalmology:
December 19, 2023:
Conclusion
Prominent corneal nerves with pannus, extensive differentials, keratoconus?
Differentials:
-Keratoconus
-Fuchs
-Posterior polymorphous corneal dystrophy
-Acanthamoeba
-HSV/VZV
-MEN 2A/MEN 2B/MNS
-Refsum disease
-Riley-Day syndrome
-NF-1
-Leprosy
-Lipoid proteinosis
-Ichthyosis
Plan
Trafloxal once daily in the left eye
Hylan as needed
Follow-up appointment, Obtain OLCD data
Follow-up appointment: 3 weeks, check-up 3-4 weeks preferably on Tuesday morning
With corneal topography
----
Microbiological results:
December 20, 2023
1^st report:
Material: Eye
Collected on: -
Antibiotic therapy:
Clinical data: Antibiotic use: none
Question: Routine eye culture
Routine eye culture
Culture
1 Staphylococcus aureus slight
Conclusion
No anaerobic microorganisms cultured
Sensitivity
1
R Penicillin
S Flucloxacillin
R Amoxicillin
S Amoxicillin+Clavulanic acid
S Gentamicin
S Tobramycin
S Vancomycin
S Ciprofloxacin
S Erythromycin
S Clindamycin
S Doxycycline
S Trimethoprim/Sulfamethoxazole (co-trimoxazole)
S Mupirocin
S Fusidic acid
S Rifampicin
S Chloramphenicol
Explanation of sensitivities:
S = sensitive, I = intermediate / reduced sensitivity, R = resistant
2^nd report:
Material: Eye
Collected on: -
Clinical data: Antibiotic use: none
EXAMINATION RESULT UNIT INTERPRETATION
-----------------------------------------------------------------------------------
Adenovirus PCR No DNA detected
C. trachomatis No DNA detected
N. gonorrhoeae No DNA detected
Herpes simplex virus 1 PCR No DNA detected
Herpes simplex virus 2 PCR No DNA detected
Varicella zoster virus PCR No DNA detected
The test method is not validated for this body material.
3^rd report:
Material: Eye
Collected on: -
Clinical data: Antibiotic use: none
EXAMINATION RESULT UNIT INTERPRETATION
-----------------------------------------------------------------------------------
Acanthamoeba species PCR *
----
Letter to my GP from the ophthalmology:
December 20, 2023:
Dear colleague,
The above-mentioned patient was seen by us on December 20, 2023, at the Ophthalmology Outpatient Clinic.
Reason for visit / Referral
For a few months, the patient has been experiencing problems with her left eye. She experiences blurriness, has difficulty reading texts, her eye tears a lot, and she struggles with focusing.
Conclusion
Visible corneal nerves with pannus, past inflammation? Other pathologies?
Plan
Trafloxal once daily in the left eye
Hylan as needed
Follow-up appointment, Obtain OLCD data
Follow-up appointment: 3 weeks, check-up 3-4 weeks preferably on Tuesday morning
Requested investigations
Functional examination: OCT
Medical microbiology, eye, eye: Eye routine culture, Eye adenovirus PCR, Eye C. trachomatis/N. gonorrhoeae PCR, Eye Herpes/Varicella PCR, Eye Acanthamoeba PCR (December 20, 2023)
Medical history
For a year, the patient has experienced blurry vision and sicca symptoms, especially in the left eye. Often feels inflammation. Sees images separating, causing double vision. Often blinks. Visited -, received treatment for dry eyes and Hypromellose.
Artificial tears provide relief for sicca symptoms, but blurry/double vision in the left eye persists. Current glasses are 3 years old.
Last wore contact lenses 3 years ago, these symptoms have been present for a year.
Ocular history: -
Family ocular history: -
Relevant medical history:
Medication as per referral
Physical examination
Visual acuity with own correction OD: 1.0= S -1.75 C -1.00 axis 8
Visual acuity with own correction OS: 0.4- S -2.00 C -0.75 axis 1
Visual acuity after refraction OD: 1.0= S -1.50 C -0.75 axis 5
Visual acuity after refraction OS: ntv S 0.00 C -2.00 axis 135
Remarks on visual acuity OS: AR irregular rings and highly variable AR values

Autorefraction
Measurement method / remark: AR for cyclo.
1.0= S -1.75 C -0.75 axis 15
< 0.4- S -0.75 C -2.00 axis 150
Measurement method / remark: AR after cyclo.
S -1.00 C -0.25 axis 5
S 0.00 C -2.00 axis 135
Tonometer OD: 12 mmHg, applanation.
Tonometer OS: 12 mmHg, applanation.
Slit lamp examination OD: clear cornea, mild punctata, clean/deep anterior chamber, clear media
Slit lamp examination OS: Conjunctival hyperemia+, cornea confluent punctata centrally diffuse, visible corneal nerves, deep/clean anterior chamber, clear media
Fundus OD: pink and sharply demarcated optic discs, beautiful maculae, and no abnormalities peripherally OD
Remarks: Everting gb, inferior fornix papillae with numerous calcareous concretions
Additional investigations
OCT macula OD: no abnormalities
OCT macula OS: no abnormalities
Schirmer test: OD 7 mm and OS 3 mm (after 5 minutes with oxy)
----
Treatment report from the ophthalmology:
January 9, 2024:
Conclusion
Calmer picture, sicca with very low tear production in both eyes and complaints of dry mouth
No visible corneal nerves
Regular astigmatism in the left eye, differential diagnosis of forme fruste keratoconus
Plan
Follow-up appointment: 3 months, check-up with Bauke corneal topography, in conjunction with Dr. B
----
Treatment report from the ophthalmology:
April 11, 2024:
Conclusion
Sicca keratitis in both eyes
Plan
Follow-up appointment: 6 months, Repeat corneal topography for Mr. -
Increase Artelac to 6-8 times daily in both eyes
----
Gender: Female
Age: 28
Height: 177cm
Weight: 74kg

Guys I just wanted to tag this post, because this is 100% my issue. Props to this guy for the detailed post.
I hope sharing it gives others the same relief it gave me.
https://www.reddit.com/erectiledysfunction/s/sXTPpODyZG
My story:
I think I’ve had these issues for a while now but they got bad lately. I was diagnosed with prostatitis by a urologist and put on bactrim. But before this I was doing pelvic floor stretches and relaxation techniques for a week or so. But two days after I started bactrim (sulfamethoxazole-tmp) my symptoms faded and went away completely for almost 2 weeks. I’m talking incredibly full erections and no pain at all. It was fantastic. I also have been tapering off lexapro for a long time and my sensation is coming back, it was heaven-like (the 2 week period).
Anyways, I thought I was past it and started going super hard in the gym again, as well as having sex like a maniac. Then, I went and got hammered with buddies and then my symptoms returned that next day. Not sure it was stress, strain from gym, alcohol interacting with antibiotic, or what. Also had job interviews that week so had a lot of stressful things goin on. Still taking antibiotic FYI, I have about 3 weeks left on it.
But here I am week later and have been dealing with this flare-up the entire time. Pain has been high and my dick is shriveled 20% of the time. (The other 80% it’s just smaller than usual and cannot get a full erection). Most of the time I can consciously relax my PF from the stretches and relaxation techniques I have learned this past month. But I’ve been getting super down about it and came across that post (link above) and am absolutely convinced this is my issue. Everything he mentions about misalignment, quad-dominance, etc. lines up with me. I’ve been hitting legs a lot lately and my right glute and hamstring is extremely weak compared to the other. I did not know how to put it into words until I came across that post.
Anyways, last time it flared up like this it went away after about 8-9 days. Not sure if this was bactrim or stretches. I hope I have as quick of a turn-around as I did last time.

1:30Pm - Admitted HS Flare up left groin, left ear lobe, perineum, buttock. Open wound drainage with yellow exudate. The thing is is that I did three weeks of Septra DS (Sulfametaoxol sp? and Trimethoprim generic name) for the first three week of March with success and than it fell apart but and this is a big, the nasty thick fibrous scar tissue formed very quickly. Quite possible there is some HS shenanigans going on underneath the scaring. Metaphorically speaking, you need chainsaw to cut through the scar tissue. Just hope there are not any hairs trying to grow under the scar tissue.
Well ER physician nice. Kind. She did bring up well is it an std maybe. I laughed and told her no it not was tested three times in NYC. She is going to order a cat scan. She immediately went to the armpit area and I told her umm not there but down in the groin. Very pleasant. But no iv antibotics yet.But the ER I am currently at (last ER visit was almost 13 months ago) has definitive protocols and guidelines for ER treatment for HS.
1:45PM EST
IV Morphine. Blood drawn. Antibotics will be prescribed based on blood and urine samples.
2pm - 2:15 pm cat scan. Morphine 90% effective dull pain in where buttock groin perineum .
3PM - no abscesses but . Mupurocin cream , ketrolac (Toradol USA Name), and more Septra. Physician said the infection is superficial (on the surface not inbedded undernearthZ)
We discussed biolologics and we kinda both agreed that even though cancer runs on my father's side of the family, the risk of taking Humaira et... might be worth it. Plus I am going to see if any antibacterial soaps that contain Triclosan are still floating around. Food and Drug administration banned Triclosan in 2018 and ever since than, it been at times the equivalent of a WWE wrestling Battle Royal

Hi all,
So I'm kind of lost and absolutely don't know what to do, and I hope you guys can help me out with my options and next steps.
Since December 2022, I've been experiencing significant issues with my left eye. The main complaints are:

• Dry eyes (both eyes)
  
• Double vision (only in the left eye)
  
• Blurry vision (only in the left eye)
  
• Frequently swollen upper eyelid (only in the left eye)
  

I've had many appointments at eye clinics/hospitals. My last appointment was this past Thursday, and I was told that I need to use eye drops more frequently and that I should come back for photos in six months. I can't wait that long. I really can't continue to live with these symptoms any longer. I've stopped attending school because I was getting headaches from the double vision. I really can't endure this for another six months.
The only thing that has helped are eye ointments. Once at the eye clinic, I was given an eye ointment (HYDROCORTISONE/OXYTETRACYCLINE/POLYMYXIN B EYE OINTMENT 3.5G) that I could use for two weeks. After stopping, I was symptom-free for about four weeks. Then all my symptoms gradually returned. The same situation occurred at the hospital. I was given an eye ointment (OFLOXACIN EYE OINTMENT 3MG/G TUBE 3G) to use for two weeks. It worked well for four weeks, but then all my symptoms returned.
Could someone please review my results and provide tips on my next steps and whether there's anything I can do at all? I don’t understand anything from the reports.
I put all the reports in chronological order:
Treatment report from the ophthalmology:
December 19, 2023:
ICC outpatient / referral (Rheumatology): Low tear production with significant sicca and dry mouth, indications for Sjogren's syndrome? We would appreciate your analysis.
Stop Trafloxal.
Hylan 4-6 times daily once a day in each eye.
----
Treatment report from the ophthalmology:
December 19, 2023:
Conclusion
Prominent corneal nerves with pannus, extensive differentials, keratoconus?
Differentials:
-Keratoconus
-Fuchs
-Posterior polymorphous corneal dystrophy
-Acanthamoeba
-HSV/VZV
-MEN 2A/MEN 2B/MNS
-Refsum disease
-Riley-Day syndrome
-NF-1
-Leprosy
-Lipoid proteinosis
-Ichthyosis
Plan
Trafloxal once daily in the left eye
Hylan as needed
Follow-up appointment, Obtain OLCD data
Follow-up appointment: 3 weeks, check-up 3-4 weeks preferably on Tuesday morning
With corneal topography
----
Microbiological results:
December 20, 2023
1^st report:
Material: Eye
Collected on: -
Antibiotic therapy:
Clinical data: Antibiotic use: none
Question: Routine eye culture
Routine eye culture
Culture
1 Staphylococcus aureus slight
Conclusion
No anaerobic microorganisms cultured
Sensitivity
1
R Penicillin
S Flucloxacillin
R Amoxicillin
S Amoxicillin+Clavulanic acid
S Gentamicin
S Tobramycin
S Vancomycin
S Ciprofloxacin
S Erythromycin
S Clindamycin
S Doxycycline
S Trimethoprim/Sulfamethoxazole (co-trimoxazole)
S Mupirocin
S Fusidic acid
S Rifampicin
S Chloramphenicol
Explanation of sensitivities:
S = sensitive, I = intermediate / reduced sensitivity, R = resistant
2^nd report:
Material: Eye
Collected on: -
Clinical data: Antibiotic use: none
EXAMINATION RESULT UNIT INTERPRETATION
-----------------------------------------------------------------------------------
Adenovirus PCR No DNA detected
C. trachomatis No DNA detected
N. gonorrhoeae No DNA detected
Herpes simplex virus 1 PCR No DNA detected
Herpes simplex virus 2 PCR No DNA detected
Varicella zoster virus PCR No DNA detected
The test method is not validated for this body material.
3^rd report:
Material: Eye
Collected on: -
Clinical data: Antibiotic use: none
EXAMINATION RESULT UNIT INTERPRETATION
-----------------------------------------------------------------------------------
Acanthamoeba species PCR *
----
Letter to my GP from the ophthalmology:
December 20, 2023:
Dear colleague,
The above-mentioned patient was seen by us on December 20, 2023, at the Ophthalmology Outpatient Clinic.
Reason for visit / Referral
For a few months, the patient has been experiencing problems with her left eye. She experiences blurriness, has difficulty reading texts, her eye tears a lot, and she struggles with focusing.
Conclusion
Visible corneal nerves with pannus, past inflammation? Other pathologies?
Plan
Trafloxal once daily in the left eye
Hylan as needed
Follow-up appointment, Obtain OLCD data
Follow-up appointment: 3 weeks, check-up 3-4 weeks preferably on Tuesday morning
Requested investigations
Functional examination: OCT
Medical microbiology, eye, eye: Eye routine culture, Eye adenovirus PCR, Eye C. trachomatis/N. gonorrhoeae PCR, Eye Herpes/Varicella PCR, Eye Acanthamoeba PCR (December 20, 2023)
Medical history
For a year, the patient has experienced blurry vision and sicca symptoms, especially in the left eye. Often feels inflammation. Sees images separating, causing double vision. Often blinks. Visited -, received treatment for dry eyes and Hypromellose.
Artificial tears provide relief for sicca symptoms, but blurry/double vision in the left eye persists. Current glasses are 3 years old.
Last wore contact lenses 3 years ago, these symptoms have been present for a year.
Ocular history: -
Family ocular history: -
Relevant medical history:
Medication as per referral
Physical examination
Visual acuity with own correction OD: 1.0= S -1.75 C -1.00 axis 8
Visual acuity with own correction OS: 0.4- S -2.00 C -0.75 axis 1
Visual acuity after refraction OD: 1.0= S -1.50 C -0.75 axis 5
Visual acuity after refraction OS: ntv S 0.00 C -2.00 axis 135
Remarks on visual acuity OS: AR irregular rings and highly variable AR values

Autorefraction
Measurement method / remark: AR for cyclo.
1.0= S -1.75 C -0.75 axis 15
< 0.4- S -0.75 C -2.00 axis 150
Measurement method / remark: AR after cyclo.
S -1.00 C -0.25 axis 5
S 0.00 C -2.00 axis 135
Tonometer OD: 12 mmHg, applanation.
Tonometer OS: 12 mmHg, applanation.
Slit lamp examination OD: clear cornea, mild punctata, clean/deep anterior chamber, clear media
Slit lamp examination OS: Conjunctival hyperemia+, cornea confluent punctata centrally diffuse, visible corneal nerves, deep/clean anterior chamber, clear media
Fundus OD: pink and sharply demarcated optic discs, beautiful maculae, and no abnormalities peripherally OD
Remarks: Everting gb, inferior fornix papillae with numerous calcareous concretions
Additional investigations
OCT macula OD: no abnormalities
OCT macula OS: no abnormalities
Schirmer test: OD 7 mm and OS 3 mm (after 5 minutes with oxy)
----
Treatment report from the ophthalmology:
January 9, 2024:
Conclusion
Calmer picture, sicca with very low tear production in both eyes and complaints of dry mouth
No visible corneal nerves
Regular astigmatism in the left eye, differential diagnosis of forme fruste keratoconus
Plan
Follow-up appointment: 3 months, check-up with Bauke corneal topography, in conjunction with Dr. B
----
Treatment report from the ophthalmology:
April 11, 2024:
Conclusion
Sicca keratitis in both eyes
Plan
Follow-up appointment: 6 months, Repeat corneal topography for Mr. -
Increase Artelac to 6-8 times daily in both eyes
----
Gender: Female
Age: 28
Height: 177cm
Weight: 74kg

I am a 41 year old Puerto Rican woman. I live in Mississippi. I weigh 186 pounds and I am 5'2. I went to the doctor originally as I was having heart palpitations. This started early this month, stopped, and continues now. They did an EKG and said my heart is healthy. They did blood work and discovered my magnesium was low so they put me on magnesium oxide for a while. The heart palpitations went away. Later they checked my levels again and it was normal so they took me off of it. But the palpitations came back though it feels a tad different. They only last for like a second or two and happens throughout the evening. No other symptoms. I have checked my pulse when this occurs and it is at normal resting of 80 bpm. I'm not sure if it's possible I'm having heartburn( I'm not feeling a burning sensation though.) or acid reflux that mimics that feeling. It only happens in the evening. I have to wait till the 29th of this month to see my new doctor. I was in the ER the other day for side abdomen pain and it turned out to be a UTI. They did blood work of everything and a cat scan of most of my body including the pelvic area and the UTI is all they found. I am healthy otherwise minus having sleep apnea. Any thoughts?
Medications I currently take: bupropion hcl 150mg xl, caplyta 42mg, vitamin D3 50000, medroxypr ac inj 150mg/ml, prazosin hcl 5mg, trazodone 200mg, citalopram 50mg, bactrim ds 800-160.

Hi all,
So I'm kind of lost and absolutely don't know what to do, and I hope you guys can help me out with my options and next steps.
Since December 2022, I've been experiencing significant issues with my left eye. The main complaints are:

• Dry eyes (both eyes)
  
• Double vision (only in the left eye)
  
• Blurry vision (only in the left eye)
  
• Frequently swollen upper eyelid (only in the left eye)
  

I've had many appointments at eye clinics/hospitals. My last appointment was this past Thursday, and I was told that I need to use eye drops more frequently and that I should come back for photos in six months. I can't wait that long. I really can't continue to live with these symptoms any longer. I've stopped attending school because I was getting headaches from the double vision. I really can't endure this for another six months.
The only thing that has helped are eye ointments. Once at the eye clinic, I was given an eye ointment (HYDROCORTISONE/OXYTETRACYCLINE/POLYMYXIN B EYE OINTMENT 3.5G) that I could use for two weeks. After stopping, I was symptom-free for about four weeks. Then all my symptoms gradually returned. The same situation occurred at the hospital. I was given an eye ointment (OFLOXACIN EYE OINTMENT 3MG/G TUBE 3G) to use for two weeks. It worked well for four weeks, but then all my symptoms returned.
Could someone please review my results and provide tips on my next steps and whether there's anything I can do at all? I don’t understand anything from the reports.
Treatment report from the ophthalmology:
December 19, 2023:
ICC outpatient / referral (Rheumatology): Low tear production with significant sicca and dry mouth, indications for Sjogren's syndrome? We would appreciate your analysis.
Stop Trafloxal.
Hylan 4-6 times daily once a day in each eye.
----
Treatment report from the ophthalmology:
December 19, 2023:
Conclusion
Prominent corneal nerves with pannus, extensive differentials, keratoconus?
Differentials:
-Keratoconus
-Fuchs
-Posterior polymorphous corneal dystrophy
-Acanthamoeba
-HSV/VZV
-MEN 2A/MEN 2B/MNS
-Refsum disease
-Riley-Day syndrome
-NF-1
-Leprosy
-Lipoid proteinosis
-Ichthyosis
Plan
Trafloxal once daily in the left eye
Hylan as needed
Follow-up appointment, Obtain OLCD data
Follow-up appointment: 3 weeks, check-up 3-4 weeks preferably on Tuesday morning
With corneal topography
----
Microbiological results:
December 20, 2023
1^st report:
Material: Eye
Collected on: -
Antibiotic therapy:
Clinical data: Antibiotic use: none
Question: Routine eye culture
Routine eye culture
Culture
1 Staphylococcus aureus slight
Conclusion
No anaerobic microorganisms cultured
Sensitivity
1
R Penicillin
S Flucloxacillin
R Amoxicillin
S Amoxicillin+Clavulanic acid
S Gentamicin
S Tobramycin
S Vancomycin
S Ciprofloxacin
S Erythromycin
S Clindamycin
S Doxycycline
S Trimethoprim/Sulfamethoxazole (co-trimoxazole)
S Mupirocin
S Fusidic acid
S Rifampicin
S Chloramphenicol
Explanation of sensitivities:
S = sensitive, I = intermediate / reduced sensitivity, R = resistant
2^nd report:
Material: Eye
Collected on: -
Clinical data: Antibiotic use: none
EXAMINATION RESULT UNIT INTERPRETATION
-----------------------------------------------------------------------------------
Adenovirus PCR No DNA detected
C. trachomatis No DNA detected
N. gonorrhoeae No DNA detected
Herpes simplex virus 1 PCR No DNA detected
Herpes simplex virus 2 PCR No DNA detected
Varicella zoster virus PCR No DNA detected
The test method is not validated for this body material.
3^rd report:
Material: Eye
Collected on: -
Clinical data: Antibiotic use: none
EXAMINATION RESULT UNIT INTERPRETATION
-----------------------------------------------------------------------------------
Acanthamoeba species PCR *
----
Letter to my GP from the ophthalmology:
December 20, 2023:
Dear colleague,
The above-mentioned patient was seen by us on December 20, 2023, at the Ophthalmology Outpatient Clinic.
Reason for visit / Referral
For a few months, the patient has been experiencing problems with her left eye. She experiences blurriness, has difficulty reading texts, her eye tears a lot, and she struggles with focusing.
Conclusion
Visible corneal nerves with pannus, past inflammation? Other pathologies?
Plan
Trafloxal once daily in the left eye
Hylan as needed
Follow-up appointment, Obtain OLCD data
Follow-up appointment: 3 weeks, check-up 3-4 weeks preferably on Tuesday morning
Requested investigations
Functional examination: OCT
Medical microbiology, eye, eye: Eye routine culture, Eye adenovirus PCR, Eye C. trachomatis/N. gonorrhoeae PCR, Eye Herpes/Varicella PCR, Eye Acanthamoeba PCR (December 20, 2023)
Medical history
For a year, the patient has experienced blurry vision and sicca symptoms, especially in the left eye. Often feels inflammation. Sees images separating, causing double vision. Often blinks. Visited -, received treatment for dry eyes and Hypromellose.
Artificial tears provide relief for sicca symptoms, but blurry/double vision in the left eye persists. Current glasses are 3 years old.
Last wore contact lenses 3 years ago, these symptoms have been present for a year.
Ocular history: -
Family ocular history: -
Relevant medical history:
Medication as per referral
Physical examination
Visual acuity with own correction OD: 1.0= S -1.75 C -1.00 axis 8
Visual acuity with own correction OS: 0.4- S -2.00 C -0.75 axis 1
Visual acuity after refraction OD: 1.0= S -1.50 C -0.75 axis 5
Visual acuity after refraction OS: ntv S 0.00 C -2.00 axis 135
Remarks on visual acuity OS: AR irregular rings and highly variable AR values

Autorefraction
Measurement method / remark: AR for cyclo.
1.0= S -1.75 C -0.75 axis 15
< 0.4- S -0.75 C -2.00 axis 150
Measurement method / remark: AR after cyclo.
S -1.00 C -0.25 axis 5
S 0.00 C -2.00 axis 135
Tonometer OD: 12 mmHg, applanation.
Tonometer OS: 12 mmHg, applanation.
Slit lamp examination OD: clear cornea, mild punctata, clean/deep anterior chamber, clear media
Slit lamp examination OS: Conjunctival hyperemia+, cornea confluent punctata centrally diffuse, visible corneal nerves, deep/clean anterior chamber, clear media
Fundus OD: pink and sharply demarcated optic discs, beautiful maculae, and no abnormalities peripherally OD
Remarks: Everting gb, inferior fornix papillae with numerous calcareous concretions
Additional investigations
OCT macula OD: no abnormalities
OCT macula OS: no abnormalities
Schirmer test: OD 7 mm and OS 3 mm (after 5 minutes with oxy)
----
Treatment report from the ophthalmology:
January 9, 2024:
Conclusion
Calmer picture, sicca with very low tear production in both eyes and complaints of dry mouth
No visible corneal nerves
Regular astigmatism in the left eye, differential diagnosis of forme fruste keratoconus
Plan
Follow-up appointment: 3 months, check-up with Bauke corneal topography, in conjunction with Dr. B
----
Treatment report from the ophthalmology:
April 11, 2024:
Conclusion
Sicca keratitis in both eyes
Plan
Follow-up appointment: 6 months, Repeat corneal topography for Mr. -
Increase Artelac to 6-8 times daily in both eyes
----
Gender: Female
Age: 28
Height: 177cm
Weight: 74kg

I (26F) currently got prescribed a 5 pack of prednisone after having a bad allergic reaction to Trimethoprim / Sulfamethoxazole which I was prescribed for a uti. They also gave me a steroid shot in the butt when I went to an urgent care. In the second day of taking prednisone I felt extremely out of body, depressed, agitated, racing heart, drowsy, super bloated, I slept most of the day then went to bed early and slept through the whole night and woke up feeling a little better but still sort of sleepy and out of body feeling. Is this the prednisone making me feel like this? I’m also taking 150mg of Bupropion(Wellbutrin) and 15mg adderall and was told to take Claritin to help with the allergic reaction. Also wondering if there’s anything I can do to feel more grounded again?

25 Male 5’8. 144 pounds. Currently taking antibiotics(sulfamethoxazole-trimethoprim) could this cause Urobilinogen to be high. My bilirubin is normal range and everything else seems to be fine.

Hi everyone, I’m five days into Bactrim DS, I have five days left. So far I’m not seeing any improvement with my bloating. In fact it looks worse. When should I see improvement? Thank you 🙏🏻

Even tho I told my doctor about bactrim DS he said no you have a bigger body index. You need something stronger so he gave. Cefuroxime axetil instead. Does this work for prostatis? Anyone with experience with this drug?

I tested positive one year ago for methane dominant sibo. I was treated with xifaxin and neomycin, which did absolutely nothing for me. I became very discouraged and my doctor did not want to retest me for sibo instead she focused on changing my constipation medication. However, I still had symptoms of sibo. Finally and thankfully my doctor is treating me for sibo using Bactrim DS. She also told me to eat a low fodmap diet during treatment, is this accurate? I really want to see results from this course of treatment. I’m on day 3 of ten days of Bactrim.

Age: 21M
Height: 5'5
Weight: Roughly 130-140
No Prior Medical Issues - I do have hypochondria.
Do not drink, smoke, or use anything else
On 2 types of antibiotics for an ingrown nail infection (Cephalexin + Sulfamethoxazole/trimethoprim)
Hello! I want to start by saying I have hypochondria so there's a real chance a lot of this is in my head.
Over the past week every now and then I have a pain in the sides of my chest (Both the right side and left side, left side more often than right) I have never had this before and I'm rather concerned about it being some form of cancer.
My only symptom is some form of pain in that area, no coughing or anything. The only other thing I can think of is when I sneeze I get a slight headache but thats been going away recently.
I have a doctors appointment in 5 days but honestly I'm horrified right now and its causing me to lose sleep, does anyone have any advice?