Hi everyone,
I'm considering launching a new ready-to-drink supplement designed to replace multiple pill supplements (omega-3s, multivitamins, ashwagandha, etc.) with added thermogenic and energy-boosting benefits. Here’s what it offers:
**Key Features:** - **Thermogenic Boost:** Ingredients like green tea extract, capsaicin, and grains of paradise to support fat loss. - **Energy:** 200mg caffeine for sustained energy. - **Comprehensive Nutrition:** Essential vitamins (A, C, D, E, K2, B-complex) and electrolytes (magnesium, potassium, calcium, sodium). - **Adaptogens & Nootropics:** Ashwagandha and rhodiola rosea, etc. for mental clarity and stress reduction.
**Questions:** 1. Would you be interested in a drink like this? 2. What flavors would you prefer? 3. How much would you pay for a 12-pack? 4. Any other ingredients or benefits you'd like to see?
Thanks for your feedback!

NeuroActiv6 promises to be the ultimate multi-nutrient drink mix for your brain. It claims to enhance focus, memory, and clarity with a blend of superfoods and nootropics.
But before you scoop up a serving, can NeuroActiv6 truly deliver on its claims? This in-depth review will explore the formula, potential benefits and drawbacks, and help you decide if it aligns with your cognitive health goals.
➡️ Visit NeuroActiv6 Official Website
What is NeuroActiv6?
NeuroActiv6 is a dietary supplement designed to support brain health and cognitive function. It contains a blend of 33 fruits and vegetables, adaptogen herbs, and clinically studied neuro-nutrients that are intended to provide brain-boosting benefits.
Some of the key ingredients in NeuroActiv6 include Sensoril Ashwagandha for cortisol reduction, NeuroFactor Coffee Fruit for BDNF (brain-derived neurotrophic factor) enhancement, Organic Turmeric for inflammation management, Cognizin Citicoline for focus and concentration,
Activin Grape Seed Extract for age-defying properties, and a detoxifying blend of organic fruits and vegetables. NeuroActiv6 is manufactured and packaged in the USA and is formulated to be gluten-free, soy-free, dairy-free, allergen-free, non-GMO, diabetic-friendly, and suitable for vegetarians.

i got the chocolate flavour with lions mane, cordyceps, ashwagandha, maca root, chaga, rhodiola rosea, coffee extract & vitamin b5. if you’ve tried it please let me know how your experience was!

ConsumerLab, in their weekly highlights, mention a “recent study found that an ashwagandha extract reduced stress, anxiety, and depression, but dose and type of extract appears to matter.”
The studies they especially reference are Pandit 2024 and Pingali 2014 (though others are also mentioned in the full report) but what is interesting is that, like the KSM-66 formulas, it references a standardised extract (Sensoril).
Sensoril is standardised to not less than 10% withanolides.
The study was specific to chronic stress, taking 250 or 500 mg leaf+root extract daily for 8 weeks reduced chronic stress by about 25%. 125 mg was not effective.
https://www.mdpi.com/2072-6643/16/9/1293
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3897003/
These studies are significant though too small to be definitive.
As there are frequent queries about Ashwagandha and stress on here I hope it might help as a pointer to anyone thinking of using it for chronic stress. It doesn’t apply to other benefits such as social relaxation or reducing occasional stress.
You can look for brands containing Sensoril or at least look for that many withanolides in any decent brand. (Please search the various other posts for “which brands.”). Have to dash…

I am currently taking this stack of nootropics and substances/natural extracts for Physical and Mental Health Enhancement and Repair.

1. Phenibut HCL
   
2. Lions Mane Dual Alc Extract Tincture
   
3. Omega 3 & Astaxanthin EPA+DHA
   
4. Live cultures+Prebiotics and Probiotics
   
5. Alpha GPC
   
6. Micronised Creatine Powder
   
7. Ashwagandha
   
8. Noopept
   
9. Multivitamins with CoQ10
   
10. Bacopa Monnieri
    
11. Magnesium Glycinate
    
12. Korean Panax Ginseng
    
13. Rhodiola Rhodea Extract
    
14. Maca Root
    
15. Ginko Biloba
    
16. Siberian Ginseng
    
17. Sabroxy
    
18. H4CBD
    
19. Phenylethylamine
    
20. Modafinil
    
21. Kratom
    
22. PQQ
    
23. Bromantane
    
24. EAA (Essential Amino Acids)
    
25. Hydrapharm
    
26. Myricetin
    
27. N-Acetyl Semax Amidate
    
28. Huperzine A
    
29. SAM-E
    
30. Reishi
    
31. Chaga
    
32. Cordyceps
    
33. Maitake
    
34. Shiitake
    
35. Caffeine
    
36. NAC (N-Acetyl-Cysteine)
    
37. ALCAR ( N-Acetyl L-Carnitine)
    
38. Vinpocetine
    
39. Super Curcuma
    
40. Digestive Enzymes
    
41. Liver Support Formula
    
42. Rehab Detox Complex
    
43. Optimag Complete Magnesium Complex
    
44. OptiVision (Vision and Eye Health)
    
45. PRL-8-54
    
46. Celtic Salt (82 Minerals)
    

This is my Limitles Nootropic Stack

I've been experimenting with a variety of dietary supplements but haven't noticed any effects, positive or negative. Here's the list:

• Ashwagandha
• Shilajit
• Lion's Mane mushroom
• Tongkat Ali
• Maca
• NAD+
• NAC
• S Lipoic Acid
• L Carnitine
• B Complex
• CoQ10
• 5-HTP
• Magnesium Neuro
• Green Tea Extract
• BCAA
• Vitamin C -L Citruline -Zinc -Fish oil -Spiruline -Biotin -Marine collagen

I take these supplements in rotation and sometimes mix some of them into a cocktail. I've always maintained a healthy lifestyle and only started using these supplements last year. Despite using concentrated doses from reputable brands, I haven't felt any improvement. Is this normal? Should I be concerned about potential liver damage from these combinations? Do you know of any nootropics that provide a noticeable positive energy boost?

I am currently taking this stack of nootropics and substances/natural extracts for Physical and Mental Health Enhancement and Repair.

1. Phenibut HCL
2. Lions Mane Dual Alc Extract Tincture
3. Omega 3 & Astaxanthin EPA+DHA
4. Live cultures+Prebiotics and Probiotics
5. Alpha GPC
6. Micronised Creatine Powder
7. Ashwagandha
8. Noopept
9. Multivitamins with CoQ10
10. Bacopa Monnieri
11. Magnesium Glycinate
12. Korean Panax Ginseng
13. Rhodiola Rhodea Extract
14. Maca Root
15. Ginko Biloba
16. Siberian Ginseng
17. Sabroxy
18. H4CBD
19. Phenylethylamine
20. Modafinil
21. Kratom
22. PQQ
23. Bromantane
24. EAA (Essential Amino Acids)
25. Hydrapharm
26. Myricetin
27. N-Acetyl Semax Amidate
28. Huperzine A
29. SAM-E
30. Reishi
31. Chaga
32. Cordyceps
33. Maitake
34. Shiitake
35. Caffeine
36. NAC (N-Acetyl-Cysteine)
37. ALCAR ( N-Acetyl L-Carnitine)
38. Vinpocetine
39. Super Curcuma
40. Digestive Enzymes
41. Liver Support Formula
42. Rehab Detox Complex
43. Optimag Complete Magnesium Complex
44. OptiVision (Vision and Eye Health)
45. PRL-8-54
46. Psilocybin
47. LSD
48. Pinealon
49. Ibogaine
50. DSIP
51. Celtic Salt (82 Minerals)

This is my Limitles Nootropic Stack

There are several energy food supplements available on the market that people use to boost energy levels and enhance performance. Here are some common options:

1. Caffeine: Caffeine is one of the most widely used and researched energy supplements. It can be found naturally in coffee, tea, and cocoa, or in supplement form. Caffeine works by blocking the effects of adenosine, a neurotransmitter that promotes relaxation and sleepiness, leading to increased alertness and energy.
2. Creatine: Creatine is a naturally occurring compound found in small amounts in certain foods and produced by the body. It's involved in the production of ATP, the primary energy currency of cells, particularly during high-intensity exercise. Supplementing with creatine can help improve performance in short-duration, high-intensity activities like weightlifting and sprinting.
3. B-vitamins: B-vitamins, including vitamin B12, B6, and folate, play essential roles in energy metabolism and the production of ATP. Deficiencies in these vitamins can lead to fatigue and decreased energy levels. B-vitamin supplements are often included in energy-boosting formulas or taken separately to support energy production.
4. Adaptogens: Adaptogens are natural substances that help the body adapt to stress and promote overall health and well-being. Examples include ginseng, rhodiola rosea, and ashwagandha. These herbs are believed to enhance energy levels, reduce fatigue, and improve mental clarity and focus.
5. L-carnitine: L-carnitine is an amino acid derivative that plays a role in energy metabolism by transporting fatty acids into the mitochondria, where they can be converted into ATP. Supplementing with L-carnitine may help increase energy levels, improve exercise performance, and enhance fat burning.
6. Coenzyme Q10 (CoQ10): CoQ10 is a compound that's naturally produced by the body and found in certain foods. It plays a critical role in energy production within cells and is particularly abundant in organs with high energy demands, such as the heart and muscles. CoQ10 supplements are sometimes used to support energy levels, especially in older adults or individuals with certain medical conditions.
7. Pre-workout supplements: Pre-workout supplements are formulations containing various ingredients designed to enhance energy, focus, and performance during exercise. Common ingredients include caffeine, creatine, B vitamins, amino acids, and herbal extracts.

While these energy supplements can be effective for some people in certain situations, it's essential to use them responsibly and in moderation. Always consult with a healthcare professional before starting any new supplement regimen, especially if you have underlying health conditions or are taking medications. Additionally, prioritize getting energy from whole foods and maintaining a balanced diet, as supplements are not a substitute for proper nutrition.

There are two main approaches for boosting testosterone in older men - over-the-counter supplements/boosters or prescribed testosterone replacement therapy (TRT).
For over-the-counter options, some of the most promising natural testosterone boosters include:

• Vitamin D and zinc - Being deficient in these nutrients can contribute to low T. Supplementing may help raise levels modestly.
• Fenugreek - Studies show fenugreek seed extract can significantly increase total and free testosterone.
• Ashwagandha - This herb seems to boost T while also reducing cortisol, the stress hormone that suppresses testosterone.

However, the evidence on the effectiveness of supplements is still quite limited. Most produce modest results at best compared to TRT.

In a society increasingly dominated by screens and convenience, the sedentary lifestyle has become a pervasive adversary, silently undermining our health and vitality. With decades of experience in the realm of natural health, I’ve witnessed firsthand the transformative power of integrating movement into our lives. It’s not merely about combating inactivity; it’s about rekindling our innate connection to wellness and vitality. Let us explore, in greater depth, the multifaceted risks of sedentarism and the path to reclaiming our health.
The Ageing Conundrum: Movement as Medicine
The journey through aging is one marked by many crossroads, and the path we choose can significantly influence our destination. The study from Tokyo provides a compelling narrative: movement, even in the later chapters of life, can be a potent elixir against the encroachment of functional disability. This isn’t just about adding years to our life but injecting life into our years. For the frail among us, the message is particularly poignant. Even modest increases in physical activity can illuminate a path away from the shadows of disability, proving that it’s never too late to transform our health trajectory.
However, the insidious nature of sedentary behavior casts a long shadow over our potential for a vibrant old age. As the study indicates, prolonged periods of inactivity elevate the risk of functional disability, independent of our efforts to remain active. This paradox underscores the importance of an integrated approach to wellness, one that encourages movement throughout the day, not just in designated exercise sessions. It’s a holistic call to action, inviting us to weave activity into the very fabric of our daily routine, turning the mundane into opportunities for movement.
Work’s Double-Edged Sword: Transforming Stress into Strength
The modern workplace often demands much but offers little in the way of physical engagement. The Finnish study sheds light on a troubling trend: adverse work conditions not only fuel stress but shepherd us into sedentary habits that compound our health risks. This toxic brew of mental strain, physical stagnation, and job dissatisfaction creates a perfect storm, eroding our health and pushing us toward clusters of risk behaviors that include inadequate sleep and a lack of physical activity. It’s a stark reminder that our professional environments have a profound impact on our health, often in ways we might not immediately recognize.
The solution lies not in a single action but in a cultural shift towards workplaces that value and promote health. Encouraging breaks for movement, creating spaces for physical engagement, and fostering a culture that values the balance between work and wellness are critical steps forward. By transforming our workplaces into arenas that support physical activity, we can combat the sedentary lifestyle and its myriad risks, turning stress into an opportunity for strength and renewal.
The Youthful Predicament: Charting a Course for Future Health
Adolescence is a pivotal time, laying the groundwork for future health habits. The study from South Korea highlights a concerning synergy between sugar-sweetened beverage consumption, screen time, and short sleep durations, a trio that significantly heightens the risk of obesity among youth. This triad of behaviors forms a feedback loop, each element reinforcing the others in a cycle that can be difficult to break. It’s a clarion call for interventions that address these behaviors not in isolation but as interconnected threads of a larger tapestry.
Creating environments that encourage physical activity, alongside educational initiatives that highlight the benefits of nutritious eating and adequate sleep, can help sever this cycle. Schools, parents, and communities play pivotal roles in modeling and supporting healthy lifestyle choices. By fostering an appreciation for movement, nutrition, and rest from a young age, we can empower our youth to navigate the challenges of a sedentary lifestyle, setting the stage for a lifetime of health and vitality.
The Diabetes Dilemma: A Microcosm of the Sedentary Crisis
Diabetes, particularly Type 2, serves as a stark microcosm of the broader challenges posed by sedentary living. The link between diabetes, erectile dysfunction, and depression underscores the complex interplay between chronic illness, mental health, and lifestyle choices. Sedentary behavior not only contributes to the onset of diabetes but also exacerbates its complications, weaving a web of health challenges that extend beyond the physical realm. It highlights the urgency of addressing inactivity as a key factor in managing and preventing not just diabetes but its associated conditions as well.
The path to mitigating these risks is multifaceted, requiring a holistic approach that encompasses diet, mental health support, and, crucially, physical activity. Movement becomes a critical lever in managing diabetes and its complications, offering a pathway to improved physical and mental health. By adopting a lifestyle that prioritizes regular physical activity, those living with diabetes can navigate the condition with greater resilience, underscoring the universal truth that movement is a cornerstone of health.
Herbal Formula Recommendations
Adaptogenic Blend for Stress and Energy

• **Rhodiola Rosea**: Known for its adaptogenic properties, Rhodiola can help reduce fatigue and improve energy levels, making it easier to engage in physical activity.
  
• **Ashwagandha**: This herb can help manage stress and anxiety, which are often barriers to maintaining an active lifestyle. It also supports overall vitality.
  

Anti-inflammatory and Circulatory Support

• **Turmeric (Curcumin)**: With potent anti-inflammatory properties, turmeric can help reduce joint pain and stiffness that might hinder physical activity.
  
• **Ginger**: Ginger is known to improve circulation and reduce inflammation, supporting musculoskeletal health and overall well-being.
  

Metabolic and Antioxidant Support

• **Green Tea Extract**: Rich in antioxidants, green tea supports metabolic health and can aid in weight management, crucial for individuals with sedentary habits.
  
• **Cinnamon**: This common spice can help regulate blood sugar levels, supporting metabolic balance and reducing the risk of diabetes.
  

Lifestyle Changes
Increase Physical Activity Gradually

• Introduce moderate physical activities that you enjoy, such as walking, cycling, or swimming, aiming for at least 150 minutes per week.
  
• Incorporate movement breaks into your daily routine, especially if you have a desk job. Short, frequent breaks to stand, stretch, or walk can counteract the effects of prolonged sitting.
  

Mind-Body Practices for Stress Management

• Regularly engage in mind-body practices such as yoga, tai chi, or meditation to reduce stress and enhance mental well-being.
  
• These practices not only support stress management but also improve flexibility, balance, and overall physical health.
  

Nutrition and Hydration

• Focus on a nutrient-dense diet rich in fruits, vegetables, whole grains, lean proteins, and healthy fats to support energy levels and metabolic health.
  
• Stay hydrated throughout the day, as proper hydration is essential for bodily functions and can also aid in weight management.
  

Sleep Hygiene

• Prioritize good sleep hygiene by maintaining a consistent sleep schedule, creating a restful sleeping environment, and avoiding stimulants before bedtime.
  
• Adequate sleep is crucial for recovery, energy levels, and overall health, making it easier to engage in physical activity.
  

Community Engagement

• Join community groups or activities that encourage physical activity, such as walking clubs, dance classes, or sports teams. Social support can be a powerful motivator.
  
• Volunteering for active roles in community events or projects can also provide opportunities for movement while contributing to your community.
  

Combining these herbal supports with targeted lifestyle changes offers a comprehensive approach to countering the risks associated with a sedentary lifestyle. It’s important to consult with a healthcare provider before starting any new herbal or supplement regimen, especially if you have existing health conditions or are taking medications. Remember, the journey toward improved health is a marathon, not a sprint. Small, consistent changes in both diet and lifestyle, supported by herbal supplementation, can lead to significant improvements in overall well-being.
Conclusion: A Call to Movement
The evidence is clear: a sedentary lifestyle poses significant risks to our health, from the vigor of youth through the grace of older age. Yet, within this challenge lies a profound opportunity — the chance to embrace movement as a fundamental pillar of health. This is not merely about exercise in its traditional sense but about cultivating a lifestyle that celebrates and integrates movement in all its forms.
As we stand at the crossroads of health and lifestyle choices, let us choose the path of activity and vitality. Let us find joy in the simple act of moving, whether through a walk in nature, a dance in the living room, or the choice to take the stairs. In doing so, we do not just move our bodies; we move closer to a life of wellness, vitality, and joy.
Sources:

1. A study on the dose-response associations between physical activity and sedentary time with functional disability in older adults with or without frailty found significant associations between sedentary time and functional disability. [View Article](https://www.ncbi.nlm.nih.gov/pubmed/38721536)
   
2. Research on the prevalence of erectile dysfunction and depression among male patients with Type II diabetes highlighted the potential impact of a sedentary lifestyle on both physical and mental health. [View Article](https://www.ncbi.nlm.nih.gov/pubmed/38716372)
   
3. A study among Finnish private-sector service workers examined the association between work-related factors and health behavior clusters, suggesting potential implications for sedentary behavior in the workplace. [View Article](https://www.ncbi.nlm.nih.gov/pubmed/38713282)
   
4. An investigation in South Korean adolescents found combined effects of sugar-sweetened beverage consumption, screen-based sedentary behavior, and sleep duration on obesity, emphasizing the need to address multiple risk factors. [View Article](https://www.ncbi.nlm.nih.gov/pubmed/38712457)
   

I started using ashwagandha today. Actually its just about an interest for me because of the internet. Personally i have no stress and anxiety in my daily work. I'm an 18 years old man, I change jobs a lot, 2 weeks ago while working as a barista, I'm working in Construction now. When i have somethings in my life i talk about it to myself. I thought it was the solution for me but i guess it wasn't. In recent weeks I started having dreams about things that "I was talking to myself and trying to figure out", wake up breathless from my dreams even my nose isn't stuffy like sleep apnea. I can't fix that just talking to myself thing anymore but last things that happened maybe because of this.
This oxygen pharma said to me take ashwagandha 1 tablet in morning on an empty stomach and 1 tablet before sleep. Idk if its going to a little help but i'll write my experiences from this supplement.
https://preview.redd.it/m7sgrblmaczc1.jpg?width=1536&format=pjpg&auto=webp&s=13bd8d50e5bc89a448812580112a693bdf2147a1
https://preview.redd.it/aqapqkymaczc1.jpg?width=1536&format=pjpg&auto=webp&s=0b062dd66ada369d85b780fd3b4565792968c8d1

The Hormone-Acne Link

A recent study published in the Journal of Clinical Medicine Research investigated the correlation between hormone levels and acne severity. The study found that there was a significant positive correlation between acne grade and levels of certain hormones, including testosterone, dehydroepiandrosterone sulfate (DHEAS), and insulin-like growth factor-1 (IGF-1) [1].
These findings suggest that imbalances in these hormones may contribute to the development and severity of acne. In particular, high levels of androgens like testosterone and DHEAS can stimulate the production of sebum, the oily substance that can clog pores and lead to acne breakouts.

Natural Remedies for Hormonal Acne

While there are many pharmaceutical treatments available for hormonal acne, some people may prefer to try natural remedies first. Here are some herbs and supplements that may help balance hormone levels and improve skin health:

1. Saw Palmetto: This herb is often used to reduce levels of dihydrotestosterone (DHT), a potent form of testosterone that can contribute to acne.
2. Fenugreek: Some studies suggest that fenugreek may help increase testosterone levels and improve symptoms related to low testosterone, such as low libido.
3. Ashwagandha: This adaptogenic herb is believed to help manage stress and may have a positive impact on testosterone levels.
4. Stinging Nettle: This plant is thought to help reduce DHT levels by inhibiting the enzyme that converts testosterone to DHT.
5. Zinc: This mineral is important for hormone production, and zinc supplementation may help increase testosterone levels, especially in those with a zinc deficiency.
6. Vitamin D: Often considered a hormone rather than a vitamin, adequate levels of Vitamin D are associated with maintaining optimal testosterone levels.
7. Green Tea Extract: Contains compounds that are believed to help reduce DHT levels. A randomized, double-blind, placebo-controlled clinical trial found that supplementation with green tea extract improved acne in post-adolescent women [2].
8. DIM (Diindolylmethane): Found in cruciferous vegetables and in supplement form, DIM is thought to support the metabolism of estrogen.
9. Spearmint Tea and Vitex: These herbs may be particularly helpful for women with hormonal acne.

The Role of Insulin Resistance

In addition to androgens and other sex hormones, insulin resistance may also play a role in the development of acne. Research indicates that administration of sex hormones, such as testosterone to females and ethinyl estradiol to males, can induce insulin resistance in healthy subjects [3]. This suggests that both androgens and estrogens can influence insulin sensitivity, although the mechanisms and outcomes may vary.
Furthermore, a study found that progesterone increases skeletal muscle mitochondrial H2O2 emission in nonmenopausal women, which is linked to insulin resistance [4]. This suggests that progesterone could play a role in the development of insulin resistance through its effects on mitochondrial function.
The combined effects of estrogen and progesterone on insulin resistance are complex and can be influenced by factors such as the method of hormone delivery (oral vs. transdermal) and the presence of other conditions like polycystic ovary syndrome (PCOS). Some studies suggest that certain combinations of estrogen and progesterone can have neutral or even beneficial effects on insulin sensitivity [5].

Conclusion

Hormones play a significant role in the development and severity of acne. Imbalances in androgens, estrogens, and insulin sensitivity can all contribute to the formation of acne lesions. While there are many pharmaceutical treatments available, some people may prefer to try natural remedies like herbs and supplements to balance hormone levels and improve skin health. As always, it's important to consult with a healthcare provider before starting any new treatment regimen.

References:

1. Correlation Analysis Between Hormone Level and Acne Grade
2. Does supplementation with green tea extract improve acne in post-adolescent women? A randomized, double-blind, and placebo-controlled clinical trial
3. K. H. Polderman et al., The Journal of Clinical Endocrinology and Metabolism
4. Daniel A. Kane et al., American Journal of Physiology. Endocrinology and Metabolism
5. Christopher P. Spencer et al., Metabolism: Clinical and ExperimentalThe Hormone-Acne Link

Join the discord here:
https://discord.com/invite/JJREjUhgc9
Blog:
https://acnehelp.space/

In the contemporary landscape of dietary science and health, the discourse surrounding ultra-processed food occupies a pivotal role. This discussion bridges the gap between the mechanics of food processing and its far-reaching implications for human health, nutrition, and disease management. The essence of a healthy diet, rich in nutrients and low in artificial additives, stands in stark contrast to the reality of today’s global food systems, which are increasingly dominated by ultra-processed foods. These foods, characterized by high levels of refinement and the presence of numerous additives, preservatives, and artificial ingredients, have become a cornerstone of modern consumption patterns, with profound implications for public health.
Unpacking the Consequences of Convenience
Ultra-processed foods have reshaped the culinary landscape under the guise of convenience, offering time-saving solutions for the fast-paced lifestyles of the 21st century. However, this convenience comes at a cost, not just economically but in terms of health outcomes. The nutrient-depleted nature of these foods, combined with their high caloric density and content of unhealthy fats, sugars, and salts, poses significant health risks. These include an increased predisposition to obesity, type 2 diabetes, cardiovascular diseases, and a myriad of other chronic health conditions.
Illuminating Studies on Diet and Disease
Recent scientific inquiries have shed light on the specific health risks associated with the consumption of ultra-processed foods. One study focusing on the consumption of red, white, and processed meat and its association with kidney damage and diabetic nephropathy (DN) in women reveals a direct correlation between the intake of processed meats and the odds of developing microalbuminuria, severe albuminuria, higher blood urea nitrogen (BUN) levels, and DN. This underscores the tangible health risks posed by certain types of processed foods, further illustrating the importance of dietary choices in the prevention and management of chronic diseases.
Another pivotal study examining the metabolic profiles and long-term risk of depression, anxiety, and stress-related disorders provides critical insights into the relationship between diet, metabolic health, and mental well-being. The findings highlight how high levels of glucose and triglycerides, coupled with low levels of high-density lipoprotein (HDL), could significantly increase the risk of developing psychiatric disorders. These discoveries underscore the broader implications of dietary choices, not just on physical health but also on mental and emotional well-being.
Towards a Nutrient-Rich Future
The evidence presented by these studies serves as a compelling argument for a shift towards more nutrient-rich, minimally processed diets. Such diets not only support physical health but also offer protective benefits against mental health disorders. The promotion of whole foods, rich in natural vitamins, minerals, and antioxidants, is paramount in counteracting the health risks associated with ultra-processed food consumption.
Herbal Formula
Given the concerns highlighted regarding the consumption of ultra-processed foods and their impact on health, particularly in relation to metabolic dysregulation and its potential to exacerbate conditions such as diabetic nephropathy, depression, anxiety, and stress-related disorders, a herbal formula aimed at supporting metabolic balance, renal health, and mental well-being would be beneficial. The following is a carefully curated herbal formula based on phytochemical knowledge and clinical insights, designed to support the body’s natural processes in addressing these concerns:
Herbal Formula for Metabolic and Mental Well-being

1. **Berberine (from Berberis vulgaris or Coptis chinensis)**
   - **Role**: Berberine has been extensively studied for its positive effects on blood glucose regulation and lipid metabolism. It can help in managing high blood glucose levels and improving lipid profiles, which are common issues stemming from the consumption of ultra-processed foods.
   - **Dosage**: 500 mg, taken 2-3 times daily before meals.
   
2. **Cinnamon (Cinnamomum verum)**
   - **Role**: Cinnamon is well-regarded for its ability to improve insulin sensitivity and lower blood sugar levels, making it a valuable addition to a metabolic-supporting herbal formula.
   - **Dosage**: 1-2 grams of powdered cinnamon daily or as a tea.
   
3. **Dandelion root (Taraxacum officinale)**
   - **Role**: Dandelion root supports liver health and has mild diuretic properties, which can aid in detoxification processes and support renal health, potentially mitigating risks associated with diabetic nephropathy.
   - **Dosage**: 500-1000 mg of dried root as a tea or in capsule form, daily.
   
   1. **Omega-3 Fatty Acids (from flaxseeds or algae)**
   - **Role**: While not an herb, omega-3 supplements can support mental health, lower triglycerides, and have anti-inflammatory properties, addressing several concerns raised by ultra-processed food consumption.
   - **Dosage**: 1-2 grams daily of EPA and DHA combined.
   
4. **Ashwagandha (Withania somnifera)**
   - **Role**: Ashwagandha is an adaptogen that helps in managing stress and anxiety. It supports the body's resilience to stress and can improve overall well-being.
   - **Dosage**: 300-500 mg of root extract daily.
   

Considerations
- **Safety and Interactions**: Before starting any herbal regimen, it's crucial to consult with a healthcare provider, especially for individuals taking prescription medications, pregnant or breastfeeding women, and those with pre-existing health conditions. For example, St. John's Wort is known to interact with a wide range of pharmaceuticals.
Conclusion
The dialogue on ultra-processed food, food processing, and nutrition intersects at the crucial point of human health and disease prevention. As we navigate the complexities of modern dietary patterns and their health implications, it becomes increasingly clear that the path to a healthier future lies in embracing diets that prioritize nutritional quality over convenience. By fostering greater awareness of the impacts of dietary choices and advocating for food systems that support the availability and accessibility of healthy, minimally processed foods, we can make strides towards mitigating the health risks associated with ultra-processed food consumption. This journey towards improved health and nutrition requires a collective effort, informed by scientific evidence and guided by a commitment to the well-being of individuals and communities worldwide.
Sources:
https://pubmed.ncbi.nlm.nih.gov/38564219/
https://pubmed.ncbi.nlm.nih.gov/38710706/
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Причините за анксиозност и депресија не се лесни за откривање. Прво треба да го откриеш проблемот, па потоа да бараш соодветен лек. Затоа не брзај со никаков “инстант” лек, но прво барај го проблемот, а со тоа ќе го пронајдиш и лекот. Психичките болести психологијата ги дели во три категории, оние кои потекнуваат од мозокот, душата, или комбинација од двете. Често се случува проблемот да е само во мозокот, односно збир на лоши навики, лоша исхрана, недоволно сон, недоволно свеж воздух, недоволно образование за тоа како се лачат хормоните кои ќе ти помогнат во овај случај како серотонин, допамин и др. Тие кои се душевно болни потешко се третираат, а причините се трауми, некои наследени состојби, и сл. Најчесто проблемите кај нас младите доаѓаат од недоволно образование за менталното здравје, лошите навики и надворешни влијанија со кои сме пораснале.
Претпоставувам дека си млад, јас не сум многу млад(32.5) а сум имал тешка депресија, анксиозност и што не. Сум пушел трева, пиел и све по ред, но тоа што ми помогна е истражувањето за тоа како функционира мозокот, прифаќањето на сето тоа и времето кое требаше да помини за сето тоа да го спроведам во пракса. Во еден момент кога се решив да читам за некои успешни личности низ историјата, открив дека сите до еден, без разлика дали некој бил уметник, научник, филозоф, светител, и слично, буквално сите до еден не станале тоа што биле без огромно образование во сите области, така што тоа не станало преку ноќ туку со крвава борба и жед за вистината. Сите успешни луѓе имале војничка дисциплина, не пиеле, не се дрогирале, јаделе исклучиво најздрава храна, секој ден станувале и се буделе во исто време, често оделе сами на прошетки во природа(тоа доста помага за разговор со себе и разјаснување на некои лоши мисли и доаѓање до големи идеи), нон стоп го надградувале нивното образование и често тие луѓе ете на пример Бетовен или Тесла, до крајот на животот не биле сметани за “големи” или многу значајни, константно имале предизвици од општеството и многу од нив се соочувале со депресија и сл, но без разлика, со искуството и стекнатата дисциплина низ годините научиле дека животот не е лесен и дека треба макотрпна работа за големи дела. Поради нивните дела ние денес имаме толку многу удобности што обичните луѓе од изминатите векови не можеле ниту да ги замислат. Топла вода во секое време, врвна музика во секундата, образование на само клик од маус, печена кокошка преку улица🤣..буквално сѐ.
Значи станавме луѓе со мн слаба волја ми е муабетот. Сѐ имаме, а ништо немаме. Можеби и тоа не направи вакви. Генерациите пред нас кои немале многу и кои биле војска се многу посилни, мнозинството имаат фамилии, стабилни работи, купиле станови и куќи, изградиле животи. Како? Со мн работа и дисциплина. Ние денес за разлика од нив, не треба толку да црнчиме зошто има полесни начини како да се направат пари, но мораме да ја стекниме дисциплината и едноставно да станиме свесни дека големите работи не можат да дојдат преку ноќ. За да се изградиш како човек и да имаш силна психа, потребно е машки да се соочиш со проблемите, треба голема храброст и одлучност за спроведување на решенијата, без одлагање. Ние само одлагаме и така животот си врви.
Корисна терапија е когнитивно бихевиориалната, би требало да има такви психијатри/доктори кај нас кои ја практикуваат, доколу сакаш да пробаш нешто такво. Или разговор со искусен психолог можеби би помогнало. Но можиш да учиш за КБТ и други терапии на интернет, има бесплатни материјали. Друго, треба да се образоваш за тоа како се лачат тие хормони кои ги спомнав. Редовен сон, вежбање, здрава храна, хобиа, учење на нови работи, дружење со позитивни луѓе. Мн битен е свеж воздух. Мозокот го искористува 80% од воздухот кој го дишиме, така да имаме голема потреба за воздух и чести прошетки. Често со една долга прошетка ќе си го подобриш влошеното расположение. Суплементацијата доста помага, како inositol/choline, ALCAR, curcumin extract, multivitamins, и некои кои ќе помогнат во лачење на тестостерон(денес машките имаме огромен недостаток на тест. од непознати причини) како tongkat ali, tribulus, ashwagandha, и сл., не ги знам сите треба да побараш што е најдобро. Јас користам тонгкат. Сите ги има кај нас. Јас додуша нарачувам онлајн. Ако подолг период го практикуваш сето ова и сепак не си подобар, тогаш треба антидепресиви(но не верувам дека си за нив ако си немал стварно мн тешко минато), јас ги земав нешто повеќе од година кога ми беше претерано тешко(се одвикнував од зависности), и многу ми помогнаа.
Марихуаната е зло, пушев многу години, ми требаа години да се одвикнам и да се опоравам. За денешната марихуана, Австралиски научник изврши испитување кое траеше над 20 години и дојде до заклучок дека потентноста достигна толку високо ниво, така што ствара зависност целосно идентична како и кај потешките дроги. За споредба, во 60тите нивото на тхц(психоактивната супстанца) беше околу 1%, денес е минимум 10%, а најчесто е над 15%. Тој процент е огромен, што тоа не значи само дека марихуаната е појака за над 15 пати, туку дека и количината на цбд(состојката која делува позитивно на когнитивните способности) е непостоечка! Постојат добри истражувања кои докажуваат дека и најмала конзумација на марихуана физички ја променува структурата на мозокот, а кај тинејџерите тоа е мн поизразено. Редовната конзумација на марихуана, ги троши резервите на сите добри хормони, така што мозокот не е во можност повеќе самиот да ги лачи, и така се ствара зависност, депресија, анксиозност, панични напади, итн. Таа негативно влијае скоро врз сите делови на мозокот, посебно кај делот за меморија. Не си играјте со ова зло.
Човекот не е свесен колку мозокот е способен за сам од себе да лачи добри хормони, секако со помош на човекот кој мора да научи како да го насочи и развие мозокот. Сите овие модерни глупости кои ни ги сервираат, се со цел психички и физички да се уништи човекот. Секој може да провери колку е намален процентот на плодноста кај мажите и жените, зголемените болести од секаков вид(најповеќе психички), намален тестостерон кај мажите(најбитен хормон).
Исто така сакам да додадам дека за мене голема улога игра верата, па дури и научно е докажано дека молитвата помага за лачење на тие добри хормони во мозокот. Иако одам во црква, не сум од тие верници кои сметаат дека доколку не одиш в црква си еретик или безбожник, разбирам дека тоа е мн лична работа и дека секој си има различна духовна потреба, но сметам дека вербата во Бог како добра сила(па дури и да не го разбираш тој Бог кој се проповеда), влијае доста позитивно кај многу луѓе и е најчесто главната инспирација кај големите луѓе низ историјата кои направиле многу големи и добри дела за човекот. Ти посакувам брзо опоравување!
Тл. Др.: Човекот е комплексно битие. Не посегнувај по инстант решенијата кои ти се нудат. Мозокот е доволно способен да се справи со скоро сите проблеми. Природните лекарства не се за занемарување. А во краен случај постојат многу посоодветни лекови како антидепресиви(тие би ги преопорачал само доколку ништо друго не помага). Образувај се за причините на анксиозноста и депресијата, и ќе го пронајдиш лекот.

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Hello, I am in my mid 30's and last approx 5 years have "mild" insomnia - trouple to fall asleep and waking up after 2 cycles (3h), then fully awake for 3-4 h, then got another one cycle of sleep (mostly REM rebound) if lucky.. Last 2 years I got MIRTAZAPINE 7,5 mg (low sedative dose) and it really helped a lot with sleep, I got 6-7,5h of sleep, BUT.. brain fog, did not feel that refreshed at the morning, no REM sleep, masive weight gain etc.. So I tappered it of 2 months ago.. (5-htp helped with withdrawal side effects)..
Another thing, I really believe my sleep hygiene is if not perfect then well above average -

• watching sunrise at the morning and sunset at the evening
• 18 degrees celsius bedroom, absolute quiet and metal blind = total dark
• Also use bluelight block glasses 2 hours before sleep
• also got dopamine workouts most of the afternoons in the week (jogging, weights, hiit)
• I am fit, no smoking, coffe, drugs, alcohol, no overweight, perfect BMI, no sleep apnea (even sleep on stomach), healthy diet (mediteranean).
• I also try EYE lateral movements

withdrawal from MIRTAZAPINE was tought - brain needs the drug and refused to sleep at all. But I readed all the reddit and decided to bought 20+ supplements to find the best stack that works for me. And it really helped me and I am now in 60% of my journey to perfect sleep (I sleep 4,5 - 6h a night now, but got REM and feel better at the morning than on MIRTAZAPINE).
I tried: 5-htp, Tryptophan, Tyrosine, Omega 3, Ashw, Taurine, Theanine, Lavekan, Atarax, Mag Threonate, MAG glycinate, Glycine, garlic, B complex, GABA, Apigenin, PhosphatidylSerine, Bacopa, Melatonin, Val root etc.
Still in testing and have many ideas to find ideal stack, but it seems there are holy grail in these 3-6 basic components, so my ULTIMATE SLEEP STACK will probably be based on these:
(All of them roughly 0,5 - 1,5 hours before bed.)

1. L-Theanine (100-200mg) - I will try up dose to 400, 600+mg, it seems like this did no cause insomnia in overdosing and seems to be part of most sleep stack and I really believe it is a must in any sleep stack.
2. Apigenin (50mg)- will also try higher dose as soon as I test other stuff
3. Magnesium bisglycinate (200-400mg) - not totally sure abour it, maybe it is a reason for waking up after 3hours, but it helps fall asleep so it is good thing for now.
4. anoher serious candidate for sleep stack for me is GLYCINE. (1g+)not sure if this guy works long term, because it was main part of my initial stack that worked well for few days and then caused insomnia.. Maybe it was due to Magnesium Threonate, and glycine is actually key ingredient and works well, needs another testing or need to adjust dose little bit better. further testing needed, but I would like to take it due to other benefits
5. PhosphatidylSerine - also not sure about this one but it seems like it does not cause insomnia at worst., maybe really helps with cortisol and calming.
6. Tryptophan (before bed 500mg, afternoon 500mg) - It was stuff I was experimenting a lot before mirtazapine at the beginning of my insomnia (5years ago) and it partially worked, never got final solution tho. It seems like it worked only sometimes (many other conditions needs to work). It needs carbs, B6 and other stuff to work, it should not harm me anyway so I take it 2x a day. I am sure part of the problem with my sleep and mood is lack of serotonin, so I guess this stuff helps with mood at least if not that much with sleep.

So these seems to be key ingredients, but still not finished, I got nice knocking off effect after taking this, but still up after 3hours, then I need to take it all (most of it)again and fall asleep again for next 1,5 - 3hours. Not near to 7,5 hours, but sleep seems to be little bit better (more refreshing + more REM) than on mirtazapine.
Beside of that I use in the afternoon - evening (18:00) calming stuff to little bit lower my cortisol - ASHWAGANDHA, L-Taurine, OMEGA 3, Garlic. Not sure how effective it is but at least it should not harm sleep more at worst. At the morning I take things like Tyrosine, EGCg, NAC etc. Nothing that would ruin my sleep, take it at the morning to be sure.
So other stuff I would like to TEST (beside of dosing/remove these above):

• California poppy - I take small dose before bed as well, and it maybe helps, not sure tho.
• Taurine - I take 2 - 4g during day (afternoon mostly), will try at the evening
• INOSITOL (1g+)- Huge expectations, should be delivered in next days, cant wait, it might help with waking up in REM after 3hours of sleep.
• B complex - this is tricky one it seems some B vits might help but some migt cause insomnia.. Was on some B complex yesterday and did not fall asleep as easy as nights without it. So I decided to order B6 (p5p - 40mg) as it is a part of famous Gorilla DREAM supplement and also helps with tryptophan. After that maybe B1, which should somehow help with breathing during night??
• Melatonin - huge expecttions before, never really worked. I was trying different doses 0,3 - 3mg. I would lke to test large doses in the future tho(10mg +) or slow released versions
• CORTISOL BLOCKER (Gorilla mind) - another huge expectations from that (wait for delivery). Mirtazapine seems to work due to 2 main reasons, it helps "naturaly" produce serotonin - (precursor of melatonin) and it lowers night cortisol a lot (might be reason for waking in the middle of the night.) so this might help with that night cortisol.
• Holy basil
• Lion's mane
• Lemons balm
• chamomile extract - for someony seems to work better than apigenin

So, I appreciate any tips and if you show us your final ULTIMATE sleep stack that works for you, thank you, REDDIT community is actually more helpful than doctors in this topic TBH=)

Been buying raw ingredients and just making my own pre-workout. Been using it for about 6 months and been liking it. I just weigh out 30 days at a time and put it in an old protein container.
Anyone else do this? Its way cheaper. My ingredients are below:
Cordyceps Extract, Ashwagandha Extract, L-Carnitine, BCAA, Taurine, L-Citrulline; DL-Malate, Beta Alanine, Creatine Monohydrate, Glutamine, Acetyl Carnitine, Beet Root Powder, Pineapple Powder, Tart Cherry Powder