Hospital mortality graph cleanliness

Prevalent Illnesses in Australia this 2024

2024.05.29 05:16 fred_reedAU Prevalent Illnesses in Australia this 2024

Australia will still be dealing with a wide range of health issues in 2024, with the colder months being the peak for seasonal illnesses including respiratory infections and influenza. This year's flu season has been especially bad, as seen by a rise in hospital admissions and recorded cases over the previous few years. To stop the virus from spreading, health authorities are advising the public to be vaccinated and to maintain proper cleanliness. Furthermore, respiratory illnesses are adding to the strain on the healthcare system. These infections are made worse by environmental variables like smoke from bushfires.
Heart disease, diabetes, and cancer are the three most common chronic illnesses, and they continue to be major health concerns. Type 2 diabetes incidence has increased noticeably, and this trend is largely attributable to lifestyle choices like eating poorly and not exercising. The national health campaign on physical activity and nutrition is one of the many healthy living projects being carried out by the Australian government. Funding for research into new medicines and early detection programmes are two further ways that cancer rates are being tackled.
Concerns about mental health are receiving increased attention as the value of psychological well-being becomes more widely recognised. An increased frequency of anxiety, depression, and other mental health conditions has been linked to the COVID-19 pandemic. Better access to mental health treatments, such as telehealth options and support programmes, is being pushed for as a result. To encourage more people to seek support and assistance, efforts are being made to lessen the stigma attached to mental health issues.
Taking care of our health is very important to make us capable of doing more and becoming more. As the saying goes, "Health is wealth".
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2024.05.29 01:33 Charupa- Acute Kidney Injury in Pregnancy: A Prospective Study

Abstract

Introduction:

When acute kidney damage occurs during pregnancy, it poses a difficult clinical problem. One of the main causes of maternal and fetal morbidity and death is pregnancy-related acute kidney injury (AKI), a significant obstetric complication characterized by a fast deterioration in renal function and several subsequent clinical problems. The objective of the study is to analyze the etiological factors, clinical manifestations, and maternal and fetal outcomes of AKI during pregnancy.

Materials and methods:

This prospective observational research involved patients hospitalized in the General Medicine and Obstetrics and Gynecology departments at Indira Gandhi Institute of Medical Sciences, Patna, for a year (October 2021 to September 2022) due to obstetric difficulties resulting in acute renal damage.

Results:

The study included 62 patients with a mean age of 25.08±4.25 years. The majority of patients in our study were aged 18-25 years (38, 61.3%), followed by 26-30 years (19, 30.6%) and >30 years (5, 8.1%). The majority of patients in our study were non-booked (52, 83.9%) and presented as emergency cases, whereas 10 (16.1%) patients had booked. In addition, 34 (54.8%) patients were primigravida, while 28 (45.1%) were multigravida. There were 25 patients in their third trimester (40.3%), 19 who were postpartum (30.6%), 10 who were post-abortion (16.1%), and eight in their second trimester (12.9%).
Upon admission, the majority of the patients showed signs of oliguria, accounting for 45 cases (72.6%). This was followed by nine cases of abnormal kidney function (14.5%) and eight cases of anuria (12.9%). Among the other symptoms, fever was observed in 25 cases (40.32%), whereas breathlessness increased to 15 cases (24.19%), edema was present in 14 cases (22.58%), vomiting and altered sensorium were observed in four cases (6.45%), abdominal pain was observed in three cases (4.83%), and burning micturition was observed in two cases (3.22%).
The most common causes of AKI in pregnancy in the present study were puerperal sepsis (18 cases, 29.0%), followed by preeclampsia/eclampsia (14 cases, 22.6%), hemorrhagic shock (10 cases, 16.1%), septic abortion (six cases, 9.7%), hyperemesis gravidarum (four cases, 6.5%), acute fatty liver of pregnancy (three cases, 4.8%), disseminated intravascular coagulation (three cases, 4.8%), drug-induced sepsis (two cases, 3.2%), and urosepsis (two cases, 3.2%). Modes of delivery in this study were normal vaginal delivery (32 cases, 51.6%), lower segment cesarean section (21 cases, 33.9%), dilation and evacuation (seven cases, 11.3%), and total hysterectomy (two cases, 3.2%). Hemodialysis was performed in 39 patients (62.9%), and 51 (82.3%) received blood transfusions. The mean systolic and diastolic BP (mmHg) were 111.37±22.60 and 71.40±18.88, respectively.
Maternal outcome data revealed that 48 (77.4%) women had fully recovered, eight (12.9%) had not recovered, 43 (69.4%) were lost to follow-up, and two (3.2%) had died. Neonatal outcomes in the present study were as follows: live birth, 43 (69.4%); abortion, eight (12.9%); intrauterine death of the fetus, five (8.1%); and neonatal mortality, six (9.7%).

Conclusion:

The diagnosis and treatment of AKI during pregnancy is a significant challenge for the treating physician because of the pathophysiological changes that occur during pregnancy, the variability of symptoms, and the fact that clinical and laboratory features may occasionally overlap.

Keywords:

acute kidney injury; hemodialysis; maternal outcome; pregnancy; sepsis.
Choudhary MK, Ahmad A, Kumari A, Prasad D, Kumar N. Acute Kidney Injury in Pregnancy: A Prospective Study. Cureus. 2024 Apr 25;16(4):e58982. doi: 10.7759/cureus.58982. PMID: 38800254; PMCID: PMC11127714.
Acute Kidney Injury in Pregnancy: A Prospective Study
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2024.05.29 01:15 healthmedicinet Health daily news May 27 2024

DAY: May 27 2024
5-27-2024

THE CASE FOR OMEGA-3 SUPPLEMENTATION TO LOWER AGGRESSION

People who regularly eat fish or take fish oil supplements are getting omega-3 fatty acids, which play a critical role in brain function. Research has long shown a basis in the brain for aggressive and violent behavior, and that poor nutrition is a risk factor for behavior problems. Penn neurocriminologist Adrian Raine has for years been studying whether omega-3 supplementation could therefore reduce aggressive behavior, publishing five randomized controlled trials from different countries. He found significant effects but wanted to know whether these findings extended beyond his laboratory.
5-27-2024

WHAT ARE ALTERNATIVES TO OZEMPIC AND WEGOVY AND ARE THEY SAFE?

With summer around the corner, telehealth outlets and medical spas are going into hyperdrive advertising the sale of semaglutide, the active ingredient in popular weight-loss drugs Ozempic and Wegovy. Recent shortages of the brand-name drugs have opened the door to copycat versions that, while legal, also raise some concerns for consumers, says Kelly Ann Barnes, Northeastern professor of pharmacy law. The copycat drugs are made by specialized pharmacies known as compounding pharmacies, which are allowed by the U.S. Food and Drug Administration to make off-label
5-27-2024

FIVE BASIC HABITS MAY HOLD THE KEY TO GOOD MENTAL HEALTH

Professor Nick Titov’s professional goal is to make himself redundant. he wants to empower more people with mild to moderate anxiety and depression to understand what they can do each day to care for their mental health. As part of this mission, Professor Titov and his team developed The Big 5, an evidence-based program encouraging five broad types of activities that are strongly linked with good mental health when performed regularly. Everyone’s
5-27-2024

COVID-19 FORECASTING TOOL ALLOWED HOSPITAL TO MANAGE PATIENT CAPACITY, RESOURCES AMID PANDEMIC’S THIRD WAVE

During the peak of the third wave of the COVID-19 pandemic in 2021, the health-care system’s capacity was stretched and hospitals across Canada relied on each other to share resources and provide care. Experts from
5-27-2024

RESEARCHERS IDENTIFY IMMUNE DYSFUNCTION AS A POSSIBLE ASPECT OF POLYCYSTIC OVARY SYNDROME PATHOLOGY

The peripubertal DHT-induced mouse model is a non-obese but insulin-resistant model of PCOS. a) Experimental design. b) Fat mass. c) Insulin levels at baseline and 15 min following glucose administration. d) Blood glucose levels during oGTT. e) HOMA-IR, calculated from fasted glucose and insulin levels. f) Glycosylated hemoglobin levels (HbA1c). A new study shows that hyperandrogenism—a key characteristic of polycystic ovary syndrome (PCOS)—affects immune cell populations in reproductive, metabolic and immunological tissues in a PCOS-like mouse model. These findings are of great importance as
5-27-2024

RESEARCH IDENTIFIES BRAIN NETWORK LINK TO STUTTERING

Common acquired neurogenic stuttering network. Common areas that were sensitive and specific across both neurogenic stuttering cohorts. Amy = amygdala; ASt = amygdalostriatal transition area; Cl = claustrum; Pall = Pallidum; Put = putamen. A new study published in the journal Brain has identified a specific brain network hub that plays a key role in stuttering. The research, by Te Whare W?nanga o Waitaha University of Canterbury (UC) Associate Professor Catherine Theys, examines two different types of stuttering—developmental and acquired—to show a clear neural
5-27-2024

THYROID DISEASE ISN’T THE END FOR YOUR CAREER PROSPECTS, REPORT FINDS

How employers behave toward workers experiencing thyroid dysfunction could play a critical part in addressing the UK’s labor market challenges. With long-term sickness on the rise in the UK, researchers at the University of Aberdeen Business School have marked World Thyroid Day (May 25) by releasing new findings which, for the first time, explore the relationship between employer sympathy and the labor market prospects of people with thyroid conditions. One in 20 people in the UK have a thyroid problem, with a significant majority of sufferers being women. Posing serious
5-27-2024

STUDY FINDS HIGH-INCOME EARNERS AT LOWER RISK OF DYING FROM STROKE

High-income earners have a 32% lower risk of dying after a stroke compared to low-income earners. The equivalent for high education is 26% lower risk. The differences in stroke survival linked to socioeconomics are striking, according to a study at the University of Gothenburg.
5-27-2024

ARTIFICIAL INTELLIGENCE COULD ALLEVIATE LONELINESS, SAYS EXPERT

Artificial Intelligence (AI) technology could offer companionship to lonely people amid an international epidemic of loneliness, says a robotics expert. Tony Prescott, a professor of cognitive robotics at the University of Sheffield, argues in his new book “The Psychology of Artificial Intelligence” that “relationships with AIs could support people” with forms of social interaction. Loneliness has been found to seriously impair human health, and Professor Prescott makes a case that advances in AI technology could offer a partial solution. He argues that people can spiral into loneliness, becoming
5-27-2024

ALZHEIMER’S REPORT HIGHLIGHTS IMMENSE CAREGIVER BURDEN—AND POTENTIAL WAYS FORWARD

Some 7 million Americans live with Alzheimer’s, and about 11 million provide unpaid care for them. Dementia caregiving can present unique challenges, including financial burdens and time constraints, as well as health complications. A report this year from the Alzheimer’s Association demonstrates the true cost of caregiving for those with the disease and calls to establish dementia care navigation throughout the U.S. to lift this burden. Not only is the estimated value of unpaid care near $14 billion in Pennsylvania alone, the report also revealed emotional and physical tolls. Nearly
5-27-2024

US FOOD AND DRUG ADMINISTRATION APPROVES ARTIFICIAL PANCREAS SYSTEM

An artificial pancreas developed by researchers at the University of Cambridge has been granted approval by the U.S. Food and Drug Administration (FDA) for use by individuals with type 1 diabetes aged 2 and older, including during pregnancy. This means that even more people living with the disease will be able to use this life-changing app. For the first time, the FDA authorized the use of the artificial pancreas system in pregnancy. CamAPS FX, produced by Cambridge spinout company CamDiab, is an Android app that can
5-27-2024

RESEARCH SAYS POMEGRANATES COULD OFFER A SOLUTION TO FATTY LIVER DISEASE

Researchers at Edith Cowan University (ECU) are investigating the effects ellagic acid, an antioxidant found in some fruits and vegetables, could have on halting and potentially reversing the damage caused by fatty liver disease. Non-alcoholic fatty liver disease (NAFLD) is the physiological manifestation of obesity in the liver. The prevalence of NAFLD has increased from 25.24% in 2015 to 29.38% in 2021, and this condition now accounts for 45.8% of all cases of chronic-liver-disease-related deaths worldwide. There currently exists no treatment for the long-term management of NAFLD; however, dietary interventions
5-27-2024

MAGIC MUSHROOMS MAY ONE DAY TREAT ANOREXIA, BUT NOT JUST YET

Anorexia nervosa is a severe mental health disorder where people fear weight gain. Those with the disorder have distorted body image and hold rigid beliefs their body is too big. They typically manage this through restricted eating, leading to the serious medical consequences of malnutrition. Anorexia has one of the highest death rates of any mental illness. Yet there are currently no effective drug treatments and the outcomes of psychotherapy (talk therapy) are poor. So we’re desperately in need of new and improved treatments. Psilocybin, commonly known as magic mushrooms,
5-27-2024

STUDY FINDS FEEDING INFANTS PEANUT PRODUCTS PROTECTS AGAINST ALLERGY INTO ADOLESCENCE

Feeding children peanuts regularly from infancy to age five reduced the rate of peanut allergy in adolescence by 71%, even after many years when the children ate or avoided peanut as desired. The new findings provide conclusive evidence that introducing peanuts into babies’ diets early will achieve long-term prevention of peanut allergy. Lead investigator Professor Gideon Lack from King’s College London said, “Decades of advice to avoid peanuts has made parents fearful of introducing peanuts at an early age. The evidence is clear that early introduction of peanut in infancy
5-27-2024

EATING MORE FRUITS AND VEGETABLES MAY LEAD TO OPTIMAL SLEEP DURATION

Good health depends on a healthy diet and sufficient exercise and sleep. There are clear associations among these components; for example, good nutrition provides energy for exercise, and many people report that getting enough exercise is important to their ability to get enough sleep. So how might nutrition affect sleep? A new study looks at the connection between fruit and vegetable intake and sleep duration.
5-27-2024

MONITORING THE H5N1 AVIAN INFLUENZA, BIRD FLU, OUTBREAK

The Centers for Disease Control and Prevention continues to actively monitor the ongoing outbreak of H5N1 avian influenza, also known as bird flu, and says that the public health risk remains low. Dr. Matthew Binnicker, director of the Clinical Virology Laboratory at Mayo Clinic, says scientists and public health officials have known about avian influenza for decades. “What’s different today is that since 2020, we’re seeing the largest outbreak of avian influenza among wild birds, poultry and backyard bird flocks,” he says. “The virus has also been found in certain
5-27-2024

INTERNATIONAL STUDY REVEALS SURPRISING TWIST IN HOW DIABETES DRUGS HELP THE HEART

A randomized, placebo-controlled clinical trial has revealed surprising new insights into how SGLT2 inhibitor drugs, originally developed for diabetes, benefit patients with heart failure. Contrary to common assumptions, these drugs may improve cardiac outcomes and heart health without acting as diuretics. Heart failure is a condition where the heart cannot pump enough blood to meet the body’s demands, often leading to fluid
5-27-2024

FIRST SEIZURE CLINICS REDUCE THE NEED FOR FUTURE HEALTH CARE, RESEARCHERS FIND

Clinics specializing in first seizures reduce the need for patients to present at emergency departments or be admitted to hospital later, Monash University-led research has found. Timely attendance, particularly within 14 days of the seizure, was associated with reduced subsequent all-cause emergency presentations and all-cause hospital admission. Later hospital admissions were reduced by about 25%. First author Dr. Yingtong Li, an adjunct
5-27-2024

CELL-TARGETING TECHNOLOGY CAN ISOLATE NEURONAL SUBPOPULATIONS AND LINK THEM TO BEHAVIORAL STATES

As gene sequencing technologies become more powerful, our understanding of cellular diversity has grown in parallel. This led scientists at St. Jude Children’s Research Hospital to
5-27-2024

WATCH OUT FOR THESE HIGH HEAT DANGER SIGNS

Climate change is pushing daytime summer temperatures higher for longer periods of time, and that can spell real danger for folks who work outside, like gardeners and landscapers. Protecting yourself in the heat and knowing the warning signs of heat-related illness is crucial, said Chris Enroth, horticulture educator at University of Illinois Extension. He should know: It happened to him. “When I was working as a landscaper, we had to sod a large backyard during a day when the temperature was over 100 degrees Fahrenheit,” Enroth said. “We were hustling
5-27-2024

STAY SAFE FROM THE SUN AND THAT BACKYARD GRILL THIS MEMORIAL DAY

Memorial Day means firing up that backyard grill for the season, hopefully under warm, sunny skies. You can be sure to enjoy the day without hazards by taking a few simple precautions, said Dr. Mike Ren, an associate professor of family and community medicine at Baylor College of Medicine in Houston. Watch out for rising heat and humidity If Memorial day is a scorcher, hydration is key, Ren said. “A good rule of thumb is to drink water regularly throughout the day, aiming for 12 or more cups; when in
5-27-2024

HAD A JOINT REPLACED? STUDY SUGGESTS INFECTION RISK MAY RISE AFTER CHEMOTHERAPY

If you’re one of the millions of Americans walking around with a new knee or hip, your odds for an infection in that joint rise if you ever have to undergo cancer chemotherapy, researchers report. “Given the number of people of receiving total joint replacements each year, as well as the cost both physically, emotionally and financially for those who develop an infection and may need subsequent treatment, we need to understand what factors may increase the risk for postoperative infections,” said study author Dr. Janet Conway. She’s an orthopedic
5-27-2024

ANTIHYPERTENSIVES LINKED TO ECZEMATOUS DERMATITIS IN SENIORS, STUDY FINDS

Antihypertensive drugs are associated with an increased risk for eczematous dermatitis in older adults, and the effect sizes are largest for diuretics and calcium channel blockers, whether antihypertensive drug use is associated with eczematous dermatitis in a longitudinal cohort study of individuals aged 60 years and older without eczematous dermatitis at baseline. The researchers found that the overall prevalence of eczematous dermatitis was 6.7% among 1,561,358
5-27-2024

RESEARCH INDICATES KIDNEYS FROM DECEASED DONORS WHO WERE ON DIALYSIS ARE SUBOPTIMAL

Receipt of a kidney from a deceased donor who underwent dialysis is associated with an increased incidence of delayed graft function, compared outcomes of transplant recipients who received kidneys from deceased donors who underwent dialysis prior to kidney donation versus recipients of kidneys from deceased donors who did not undergo dialysis in a retrospective cohort study using data from 58 U.S. organ procurement organizations. Among the donors with
5-27-2024

NEW THERAPY PROVEN EFFECTIVE AGAINST REJECTION IN KIDNEY TRANSPLANTATION

Antibody-mediated rejection (AMR) is one of the most common causes of kidney transplant failure. To date, however, no treatment has proven effective in combating this complication in the long term. As part of an international and multidisciplinary clinical study led by Georg Böhmig and Katharina Mayer, Clinical Division of Nephrology and Dialysis, Department of Medicine III at MedUni Vienna and University Hospital Vienna, a new therapeutic principle in transplant medicine has been found to be both safe and highly effective. The results were recently published in the New England Journal
5-27-2024

SHARJAH UNIVERSITY PATENTS APPLICATION FOR DISTANCE COVID-19 DIAGNOSIS

Smart Identification of Health Status based on QR Code and User Health Data. Credit: author’s own creation The University of Sharjah has been granted a patent for inventing a smart gadget with the ability to filter user information that will allow doctors to diagnose COVID-19 and other ailments from a distance. The patent, granted by United States Patent and Trademark Office on 1 August 2023, comprises “a display unit, a color code detection unit, an image filter, an optical character recognition unit, a code detection unit and an elimination unit,”
5-27-2024

STUDY REVEALS WHERE DELAYS ARE WORST

When it comes to responding to a stroke, speed is a crucial factor; the longer it takes for someone experiencing a stroke to get to a hospital, the worse the outcome will be. Yet across the United States, delays to treatment can be significant. A Yale study uncovers new insights into factors associated with treatment delays and where in the United States patients are more likely to experience slower responses. The findings, which were published May 24 in the journal Stroke, highlight where interventions should

NEW STUDY SHOWS HEAT WAVES INCREASE RISK OF PRETERM, EARLY-TERM BIRTH

The increased frequency and intensity of heat waves due to climate change puts women at a higher risk of experiencing preterm and early-term labor—jeopardizing the health and well-being of their babies. An analysis of 53 million births that occurred in the 50 most populous U.S. metropolitan areas during the 25-year period 1993–2017, showed
5-27-2024

NOISE-CANCELLING HEADPHONES, EARPLUGS AND EARMUFFS—DO THEY REALLY HELP NEURODIVERGENT PEOPLE?

Noise can make it hard to concentrate, especially for people who are extra sensitive to it. Neurodivergent people (such as those who are autistic or have attention-deficit hyperactivity disorder—ADHD) can experience different sensory sensitivities. Their nervous system may process information differently when they are exposed to sensory experiences such as bright lights, loud noise, strong smells or busy environments. Decreased sound tolerance is estimated to affect up to 70% of autistic people and is described in three ways: hyperacusis (perceiving everyday sounds as loud or painful), misophonia (an aversion to
5-27-2024

MASSACHUSETTS SHELLS OUT NEARLY $400,000 FOR VACCINE RECORD CHECKS IN STATE-RUN SHELTERS

State officials have pumped nearly $400,000 into a program to review the vaccine records of families entering the emergency shelter system, including migrants from other countries who may have foreign documentation, according to the Healey administration. Officials at Boston-based John Snow, Inc., which has long worked with the state, have been contracted to review immunization documents. Since January, more than 1,200 children in state-run shelters have had their records checked, according to the Executive Office of Health and Human Services, or HHS. Vaccine record checks have occurred since September 2023
5-27-2024

LAWSUIT ACCUSES FLORIDA’S PALM BEACH COUNTY HOSPITAL NETWORK OF SHARING PATIENTS’ PRIVATE DATA

The Palm Beach Health Network has become the latest health provider accused of illegally sharing identities and private health information of its patients with the social media company Meta, owner of Facebook. A lawsuit filed Wednesday in U.S. District Court in West Palm Beach says the health network’s websites share code with Meta that enables patients to be targeted with advertising on Facebook based on “highly sensitive personal information” they share. It names as defendants the Palm Beach Health Network Physicians Group, doing business as Palm Beach Health Network, and
5-27-2024

CAN THE PLACEMENT OF DENTAL IMPLANTS IN HEAD AND NECK CANCER PATIENTS BE DONE BEFORE RADIATION THERAPY?

Globally, head and neck cancer accounts for 5% of all cancer types, with a mortality rate of 50%. However, in the Nordic countries, head and neck cancer accounts for only 2.6% of all cancers, with a mortality rate of just 30%. But more survivors mean that many must live with extensive damage and side effects
5-27-2024

STUDY FINDS CLIMATE CHANGE INCREASES RISK OF CRYPTOSPORIDIOSIS OUTBREAKS IN NEW ZEALAND

More cryptosporidiosis outbreaks could be on the cards for Aotearoa New Zealand as extreme rainfall events become more frequent, causing higher levels of the diarrhea-causing parasite to be washed into waterways, public health researchers warn. The researchers studied clusters of cryptosporidium outbreaks around the country between 1997 and 2015 and found 13 coincided with severe weather events. Their research is published in the journal Epidemiology & Infection. It is the first study to compare clusters of outbreaks of cryptosporidiosis to severe weather events in Aotearoa.
5-27-2024

RESEARCHERS EVALUATE IMPACT OF NEW FILM’S MESSAGE ON CHILDREN’S AND ADULTS’ BODY IMAGE, SELF-COMPASSION

Unrealistic expectations about what our bodies should look like—whether from the media, friends or family—make adults and children of all ages more vulnerable to body dissatisfaction, eating disorders and other mental health challenges. In a new study published in Body Image, Flinders University experts assessing the program’s usefulness in classrooms highlight the potential for the film “Embrace Kids,” directed by 2023 Australian of the Year Taryn Brumfitt, to achieve large-scale improvements in body image
5-27-2024

STUDY FINDS INCREASED SUICIDAL THOUGHTS, SUICIDE ATTEMPTS AMONG ADOLESCENTS EXPOSED TO EARLY PHASE OF WAR IN UKRAINE

Data Collection in the War-Affected Donetsk Region and Non-War Kirovograd Region. A new study carried out by a multinational research group showed high levels of suicidal thoughts and attempts in adolescents, which were strongly associated with wartime traumatic experiences, post-traumatic stress disorder, depression and anxiety. Dr. Sanju Silwal from the Research Center for Child Psychiatry in the University of Turku, Finland, one of the lead authors, says that the study was conducted in two regions that
5-27-2024

STUDY FINDS SIGNIFICANT DISPARITIES IN THE DELIVERY OF CANCER-RELATED CARE

It’s important to ensure that care provided at US hospitals that predominantly serve Black and Hispanic populations is as high-quality as the care provided at other US hospitals. New research reveals significant disparities in the delivery of cancer-related care at minority serving hospitals (MSHs) compared with non-MSHs, however. The findings are published in Cancer. For the study, investigators analyzed information from the National Cancer Database (which accrues approximately 70% of US cancer diagnoses) to identify patients eligible for definitive treatment for breast, prostate, non-small cell lung, and colon cancers between
5-27-2024

WHO SEEKS $7 BN WITH FUND-RAISING REVAMP

The World Health Organization launched Sunday a new financing mechanism that aims to raise $7 billion of funds that can be deployed more quickly and flexibly. The UN agency has traditionally relied on commitments from its 194 member states, but often these are apportioned to specific projects with several conditions attached, including deadlines that can prove too short. WHO chief Tedros Adhanom Ghebreyesus said commitment increases would contribute $4 billion to the agency’s budget of $11.1 billion over the four years through 2028. “The Investment Round aims to mobilize the
5-27-2024

SECOND PERSON DIES OF CHOLERA ON FRENCH ISLAND OF MAYOTTE

Scanning electron microscope image of Vibrio cholerae. Credit: Wikipedia A 62-year-old woman has died of cholera in Mayotte, bringing to two the death toll from the epidemic on the French island in the Indian Ocean, health authorities said on Sunday. The woman died on Saturday at her home in Mamoudzou, the capital, the ARS health authority said in a statement. “Response teams went to the scene to disinfect the home and take care of the deceased’s family and friends”, the statement added. In May, the disease claimed its first life
5-27-2024

ALTERING CELLULAR INTERACTIONS AROUND AMYLOID PLAQUES MAY OFFER NOVEL ALZHEIMER’S TREATMENT STRATEGIES

Researchers at the Icahn School of Medicine at Mount Sinai have made a significant breakthrough in Alzheimer’s disease research by identifying a novel way to potentially slow down or even halt disease progression. The study, which focuses on the role of reactive astrocytes and the plexin-B1 protein in Alzheimer’s pathophysiology, provides crucial insights into brain
5-27-2024

BRAIN DAMAGE STUDY REVEALS PART OF THE BRAIN NECESSARY FOR HELPING OTHERS

Our willingness to help others is governed by a specific brain region pinpointed by researchers in a study of patients with brain damage to that region. Learning about where in the brain “helping” decisions are made is important for understanding how people might be motivated to tackle large global challenges, such as climate change, infectious disease and international conflict. It is also essential for finding new approaches to treating disorders of social interactions. The study, published in Nature Human Behaviour, was carried out by researchers at the University of Birmingham
5-27-2024

IMPROVING AI LARGE LANGUAGE MODELS HELPS THEM BETTER ALIGN WITH HUMAN BRAIN ACTIVITY

NSP as a computational account of discourse comprehension. (A) Humans integrate words and sentences to achieve a full understanding of discourse. In LLMs, the NSP task proposed by BERT can serve as a computational account of human discourse comprehension. (B) Illustration of the MLM task. (C) Illustration of the NSP task and its relevance to the Mason and Just model. (D) Illustration of Mason and Just’s neurocognitive model of discourse processing. Credit: Science Advances (2024). DOI: 10.1126/sciadv.adn7744 With generative artificial intelligence (GenAI) transforming the social interaction landscape in recent years,
5-27-2024

STUDY EXAMINES METABOLIC REPROGRAMMING OF BREAST CANCER TUMORS DURING NEOADJUVANT CHEMOTHERAPY

In a study published in Nature Communications, scientists have made significant strides in understanding the complex interplay between the immune system and cancer metabolism in breast cancer treatment. The research
5-27-2024

RESEARCHERS EXAMINE EVIDENCE FOR A NOVEL NEURONAL MECHANISM DRIVING ALZHEIMER’S DISEASE

An international team of clinicians and neuroscientists have published a new perspective on the process of neurodegeneration. Their findings review evidence for a mechanism upstream of amyloid including the key neurochemical driving this process. The paper, published in Alzheimer’s & Dementia, focuses on a selective group of neurons (“the isodendritic core”). These cells have a different provenance from neurons in the rest of the brain and have previously been identified as primarily
The research, by a team from Finland’s University of Helsinki, National Institute for Health and Welfare, and Turku University of Applied Sciences, is published in
5-27-2024

WHO CHIEF URGES COUNTRIES TO QUICKLY SEAL PANDEMIC DEAL

WHO countries have spent two years seeking an agreement on tackling pandemics. The World Health Organization chief on Monday urged countries to nail down a landmark global agreement on handling of future pandemics after they missed a hard deadline. Scarred by COVID-19—which killed millions, shredded economies and crippled health systems—nations have spent two years trying to forge binding commitments on pandemic prevention, preparedness and response. Negotiators failed to clinch a deal ahead of this week’s World Health Assembly—the annual gathering of WHO’s 194 member states—the deadline for concluding the talks.
5-27-2024

STUDY DEMONSTRATES HOW GUT MICROBES PROCESS STEROIDS—USING FLATULENCE

It turns out flatulence can serve a purpose beyond being uncomfortable or funny: Gas released by some gut bacteria stimulates other gut bacteria to produce a hormone involved in pregnancy and in an FDA-approved treatment for postpartum depression, according to new research led by Harvard Medical School scientists. The work shows how gut bacteria can produce new hormones from steroids in bile and, in doing so, act like an endocrine organ. This research adds to the growing list of ways gut microbiota may influence human
5-27-2024

PHYSICAL FRAILTY MAY PUT PEOPLE AT GREATER RISK OF DEPRESSION, STUDY FINDS

Individuals who meet at least one of the criteria for physical frailty are at higher risk of also developing depression, a new Yale study finds. The findings—which also include insights into the specific inflammatory molecules and changes in brain structure that could underlie this association between frailty and depression—point to a need for routine assessment of physical frailty in clinical practice, researchers said. The study was published May 23 in Nature Communications. In clinical settings, physical
5-27-2024

RESEARCH TEAM RESOLVES STRUCTURE OF CRUCIAL ENZYME FOR THE FIRST TIME

For the first time, a team co-led by CHU Sainte-Justine researcher and professor in the Faculty of Medicine at Université de Montréal, Alexey Pshezhetsky has succeeded in resolving the unique structure of the HGSNAT enzyme, a deficiency of which causes Sanfilippo syndrome, a rare pediatric disease affecting the central nervous system. Through collaboration with a team from Shanghai University, the structure of this enzyme and the mechanism of its function were revealed using high-performance

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2024.05.29 01:05 Individual-Deer-3984 Ragatouille: A guide to get started with Retrieval-Augmented Generation (RAG) with LangChain !

🚀 Exciting News! I just published a blog, Ragatouille– A guide to get started with Retrieval-Augmented Generation (RAG) with LangChain !
Based on Langchain's RAG from scratch series, in this comprehensive guide, we break down the RAG process and take you through each step to enhance and optimize your system. Here’s a sneak peek of what you'll learn:
📌 Introduction to RAG: Understand the basics of the RAG pipeline and how it combines retrieval-based systems with generative models.
🔍 Query Transformation: Learn how to refine user queries for better comprehension and accurate responses.
📚 Hypothetical Document Embeddings: Discover techniques for generating vector representations of potential documents to assess relevance.
🛤️ Routing Mechanisms: Implement intelligent routing to dynamically select the best data sources for your queries.
📝 Executable Queries: Master the art of translating user questions into executable queries.
📂 Effective Indexing: Explore indexing strategies to enhance retrieval efficiency.
🔄 Advanced Retrieval Techniques: Dive into Self-RAG, Adaptive RAG, and CRAG for tailored retrieval approaches.
💡 Generation Phase: Ensure coherent and accurate responses using the retrieved information.
🏥 Practical Application: Apply everything you've learned to build a sophisticated hospital management system using LangChain, LangGraph, and Neo4j.
👉 Check out: https://www.sakunaharinda.xyz/ragatouille-book
⬆️ I will be updating the blog soon with RAG evaluation using RAGAS and Langsmith !!! Please let me know what you guys want to appear in this blog, which will help fellow RAG enthusiasts 💭 I appreciate your constructive feedback and contributions !!
submitted by Individual-Deer-3984 to LangChain [link] [comments]


2024.05.29 00:38 imz72 Vasomune (Canadian private company) wins FDA fast track designation for ARDS

Vasomune wins FDA fast track designation for lung condition treatment
Currently in a Phase IIa study, AV-001 is being co-developed with AnGes for the prevention and treatment of ARDS in pneumonia.
May 28, 2024
Vasomune Therapeutics has announced that its novel investigational medicine, AV-001, has received US Food and Drug Administration (FDA) fast track designation for the treatment of moderate to severe pathogen-induced acute respiratory distress syndrome (ARDS).
As per the 28 May press release, fast track designation was granted based on the high unmet medical need in ARDS. The status allows for earlier interactions with the FDA in the pursuit of accelerated approval and also the possibility to undergo rolling reviews.
ARDS is a life-threatening lung injury that enables fluid to leak into the lungs, causing breathing difficulties and low blood oxygen. According to the press announcement, ARDS is characterised by high mortality rates that can reach up to 46% in patients with severe cases of the disease.
AV-001, a polyethylene glycol (PEG)-clustered Tie2 agonist peptide that was first discovered at Sunnybrook Research Institute at Sunnybrook Hospital, is designed to improve healing in patients by providing a molecular shortcut in blood vessel growth associated with wound closure.
The drug candidate is actively being evaluated in a Phase IIa study (NCT05123755) for the prevention and treatment of hospitalised patients with pneumonia-associated ARDS. The primary endpoint of the study is the safety and tolerability of multiple intravenously administered doses of AV-001 compared to placebo.
The Phase I study (NCT04737486) demonstrated a good safety and tolerability profile with strong on-target activity. There were no drug-related discontinuations or deaths, no suspected unexpected severe adverse reactions (SUSARs), and no adverse events of special interest (AESIs), as reported at the 2024 Respiratory Innovation Summit (RIS).
“Vasomune is focused on the persisting unmet needs of people grappling with ARDS and other diseases driven by vascular endothelial instability,” said president and Chief Operating Officer of Vasomune, Dr. Brian Jahns.
The Toronto, Ontario-based biotech is not the only player in the ARDS space. In October 2023, BioAegis Therapeutics was awarded a $20m contract from the US Biomedical Advanced Research and Development Authority (BARDA) for the development of plasma gelsolin for the treatment of ARDS.
Also making headway is Healios, which in April 2023, reported positive topline results from the open-label ONE-BRIDGE clinical study of somatic stem cell regenerative therapy MultiStem (HLCM051/invimestrocel) in ARDS patients across Japan.
https://www.pharmaceutical-technology.com/news/vasomune-wins-fda-fast-track-designation-for-lung-condition-treatment/
Originally discovered and designed at Sunnybrook Research Institute at Sunnybrook Hospital in Toronto, AV-001 is being developed by Vasomune Therapeutics, Inc. under a co-development agreement with AnGes, Inc. [TYO: 4563].
...
Ei Yamada, President & CEO of AnGes, said that "The FDA’s support of expedited development marks another important milestone in our endeavor to change the treatment paradigm with AV-001. We look forward to future success with the Phase 2a study, AV001-004."
https://finance.yahoo.com/news/vasomune-therapeutics-receives-us-fda-120000579.html
From the trial's page on ClinicalTrials.gov:
Enrollment (Estimated): 120
Study Completion (Estimated): 2025-03
https://clinicaltrials.gov/study/NCT05123755
Vasomune Therapeutics' website:
https://vasomune.com/
AnGes' current market cap is $64 million.
https://finance.yahoo.com/quote/4563.T
submitted by imz72 to ATHX [link] [comments]


2024.05.29 00:18 calvin324hk [H] 1000+ Games / DLCs / VR Games [W] Paypal / Wishlist / Offers

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  • Prehistoric Kingdom
  • Pretty Girls Mahjong Solitaire
  • Pretty Girls Panic!
  • Prey
  • Primal Carnage: Extinction
  • Princess Kaguya: Legend of the Moon Warrior
  • Pro Cycling Manager 2020
  • Prodeus
  • Project CARS - GOTY Edition
  • Project Warlock
  • Project Wingman (EU)
  • PROJECT WINTER
  • Propnight
  • Pseudoregalia
  • PULSAR: The Lost Colony
  • qomp
  • Quadrilateral Cowboy
  • Quake II
  • Quake II
  • Quantum Break
  • Quern - Undying Thoughts
  • Radio Commander
  • RAGE
  • RAILROAD CORPORATION
  • Railroad Tycoon 3
  • Railroad Tycoon II Platinum
  • Railway Empire
  • Rain World
  • Rayon Riddles - Rise of the Goblin King
  • Re: Legend
  • REBEL COPS
  • Rebel Galaxy
  • Rebel Galaxy Outlaw
  • Recipe For Disaster
  • Red Faction Guerrilla Re-Mars-tered
  • Red Faction: Armageddon
  • Red Riding Hood - Star Crossed Lovers
  • Red Ronin
  • RED SOLSTICE 2: SURVIVORS
  • Redout Complete Bundle
  • Redout: Enhanced Edition
  • Redout: Enhanced Edition + DLC pack
  • Regular Human Basketball
  • REKT! High Octane Stunts
  • Relicta
  • REMNANT: FROM THE ASHES - COMPLETE EDITION
  • Republique
  • Rescue Party: Live!
  • Resident Evil 0 HD REMASTER
  • Resident Evil 5 Gold Edition
  • Resident Evil 7 Biohazard
  • Resident Evil Revelations
  • Resort Boss: Golf
  • Retimed
  • RETROWAVE
  • rFactor 2
  • RiME
  • Ring of Pain
  • Rise of Industry + 2130 DLC
  • Rise of the Slime
  • Rising Storm 2: Vietnam + 2 DLCs
  • Riven: The Sequel to MYST
  • River City Girls
  • River City Ransom: Underground
  • Roarr! Jurassic Edition
  • Roboquest
  • Robot Squad Simulator 2017
  • Rogue : Genesia
  • ROGUE HEROES: RUINS OF TASOS
  • ROGUE LORDS
  • Rogue Stormers
  • rollercoaster tycoon 2
  • ROTASTIC
  • Roundguard
  • ROUNDS
  • RUNNING WITH RIFLES
  • Rustler
  • Ryse: Son of Rome
  • S.W.I.N.E. HD Remaster
  • Sailing Era
  • Saint Row
  • SAINTS ROW
  • Saints Row IV
  • Saints Row The Third
  • Saints Row: Gat Out of Hell
  • Saints Row: The Third Remastered
  • Sam and Max Devil's Playhouse
  • SAMUDRA
  • Sands of Aura
  • Sands of Salzaar
  • Saturday Morning RPG
  • Save Room - Organization Puzzle
  • Scarlet Tower
  • Scars Above
  • Scorn
  • SCP: 5K
  • SCUM
  • SEARCH PARTY: Director's Cut
  • Second Extinction
  • Secret Government
  • Serious Sam 3 Bonus Content DLC, Serious Sam 3: Jewel of the Nile, and Serious Sam 3: BFE
  • SEUM speedrunners from hell
  • SEUM: Speedrunners from Hell
  • Severed Steel
  • Shadow Tactics: Aiko's Choice
  • Shadowgate
  • Shadows Awakening
  • SHADOWS: AWAKENING
  • Shape of the World
  • She Sees Red - Interactive Movie
  • Shenmue I & II
  • SHENZHEN I/O
  • Shift Happens
  • Shing!
  • Shining Resonance Refrain
  • Shoppe Keep 2
  • Shoppe Keep 2 - Business and Agriculture RPG Simulation
  • Shotgun King: The Final Checkmate
  • Sid Meier's Civilization VI
  • Sid Meier's Railroads!
  • Sifu Deluxe Edition Upgrade Bundle (EPIC)
  • Silver Chains
  • SimCity 4 Deluxe Edition
  • Sinking Island
  • SINNER: Sacrifice for Redemption
  • Siralim Ultimate
  • Size Matters
  • Skautfold Chapters 1-4
  • Skullgirls 2nd Encore
  • Slain: Back from Hell
  • Slap City
  • Slash It
  • Slash It 2
  • Slash It Ultimate
  • Slay the Spire
  • Small World
  • Smart Factory Tycoon
  • Smile For Me
  • Smoke and Sacrifice
  • Smoke and Sacrifice
  • Smushi Come Home
  • Snail bob 2 tiny troubles
  • Sniper Elite 3
  • Sniper Elite 3 + Season Pass DLC
  • Sniper Elite 4 Deluxe Edition
  • Sniper Ghost Warrior 3 - Season Pass Edition
  • Sniper Ghost Warrior Contracts
  • Snooker 19
  • SONG OF HORROR COMPLETE EDITION
  • Songs of Conquest
  • Sonic Adventure 2
  • Sonic Adventure DX
  • Sonic and SEGA All Stars Racing
  • Sonic Generations Collection
  • Soulblight
  • Souldiers
  • SOULSTICE
  • Soundfall
  • Source of Madness
  • Spartan Fist
  • Spec Ops
  • Speed Limit
  • Spelunx and the Caves of Mr. Seudo
  • Spidersaurs
  • Spin Rush
  • Spirit Hunter: Death Mark
  • Spirit of the Island
  • Spirit of the North
  • Spring Bonus
  • Spyro Reignited Trilogy
  • Stairs
  • STAR WARS - Knights of the Old Republic
  • STAR WARS - The Force Unleashed Ultimate Sith Edition
  • Star Wolves
  • Starbound
  • Starsand
  • STASIS: Bone Totem
  • State of Decay 2: Juggernaut Edition
  • Steel Rats™
  • Stick Fight: The Game
  • Still Life
  • Still Life 2
  • Still There
  • Stirring Abyss
  • STONE
  • Strange Brigade
  • Strange Brigade Deluxe Edition
  • STRANGER
  • Strategic Command: World War I
  • Strategic Mind: Blitzkrieg
  • Strategic Mind: Fight for Freedom
  • Strategic Mind: Spectre of Communism
  • Strategic Mind: Spirit of Liberty
  • Strategy & Tactics: Wargame Collection
  • Streamer Life Simulator
  • Street Fighter 30th Anniversary Collection
  • Street Fighter V
  • Strider
  • Strikey Sisters
  • Struggling
  • Stubbs the Zombie in Rebel Without a Pulse
  • Stygian: Reign of the Old Ones
  • Styx: Master of Shadows
  • Styx: Shards of Darkness
  • SuchArt
  • Sudden Strike Gold
  • Suite 776
  • Sumoman
  • Sunblaze
  • SUNLESS BUNDLE
  • Sunset Overdrive
  • Super Buff HD
  • Super Mag Bot
  • Superbugs: Awaken
  • Superhot
  • Surgeon Simulator 2
  • Survive the Nights
  • Surviving Mars
  • Surviving Mars
  • Surviving The Aftermath
  • Swag and Sorcery
  • SWINE HD Remaster
  • Sword Legacy Omen
  • Sword of the Necromancer
  • Swords and Soldiers 2 Shawarmageddon
  • Syberia 3
  • Symphonic Rain
  • Symphony of War: The Nephilim Saga
  • Synthwave Dream '85
  • Tacoma
  • Taiji
  • Take Off - The Flight Simulator
  • Tales
  • Tales from the Borderlands
  • Tales of Vesperia™: Definitive Edition
  • Talk to Strangers
  • Tallowmere
  • Talos Principle (Gold)
  • Tangledeep
  • Tank Mechanic Simulator
  • Tannenberg
  • Team Sonic Racing
  • TEKKEN 7
  • TEMTEM
  • Terminus: Zombie Survivors
  • TERRAFORMERS
  • Terratech Deluxe Edition
  • Terror of Hemasaurus
  • Textorcist
  • Tharsis
  • The Adventure Pals
  • The Amazing American Circus
  • The Ambassador: Fractured Timelines
  • The Anacrusis
  • The Ascent
  • The Battle of Polytopia
  • The Battle of Polytopia *DLC1. Cymanti Tribe *DLC2. ∑∫ỹriȱŋ Tribe *DLC3. Aquarion Tribe *DLC4. Polaris Tribe
  • The Beast inside
  • The Blackout Club
  • The Callisto Protocol™
  • The Chess Variants Club
  • The Citadel
  • The Colonists
  • The Dark Pictures Anthology: House of Ashes
  • THE DARK PICTURES ANTHOLOGY: LITTLE HOPE
  • The Darkest Tales
  • The Dungeon Beneath
  • The Dungeon of Naheulbeuk: The Amulet of Chaos
  • The Elder Scrolls Adventures: Redguard
  • The Elder Scrolls III: Morrowind® Game of the Year Edition
  • The Elder Scrolls IV: Oblivion® Game of the Year Edition
  • The Elder Scrolls Online
  • The Escapists 2
  • THE GAME OF LIFE 2
  • The Golf Club™ 2019 featuring PGA TOUR
  • The haunted island, A frog detective
  • The Haunted Island, a Frog Detective Game
  • The Hong Kong Massacre
  • The Horror Of Salazar House
  • The Innsmouth Case
  • The Invisible Hours
  • The Jackbox Party Pack 9
  • The Knight Witch
  • The Last Campfire
  • The LEGO Movie 2 Videogame
  • The Letter - Horror Visual Novel
  • The Long Dark
  • The Manhole: Masterpiece Edition
  • The Mortuary Assistant
  • The Mummy Demastered
  • The Occupation
  • The Outer Worlds
  • THE OUTER WORLDS: SPACER'S CHOICE EDITION
  • THE PALE BEYOND
  • The Quarry
  • The Quarry deluxe
  • The Ramp
  • The Red Lantern
  • The Rewinder
  • The Sacred Tears TRUE
  • The Sexy Brutale
  • The Shapeshifting Detective
  • The Tarnishing of Juxtia
  • The Tenants
  • The Uncertain - The Last Quiet Day
  • The Uncertain: Last Quiet Day
  • The Uncertain: Light At The End
  • The USB Stick Found in the Grass
  • The Walking Dead
  • The Walking Dead - 400 Days
  • The Walking Dead Saints and Sinners
  • The Walking Dead: A New Frontier
  • The Walking Dead: Final Season
  • The Walking Dead: Michonne - A Telltale Miniseries
  • The Walking Dead: Saints & Sinners
  • The Walking Dead: Season 1
  • The Walking Dead: Season Two
  • The Way
  • The Wild At Heart
  • The Wild Eight
  • The Witness
  • Them and Us
  • They Bleed Pixels
  • Thief of Thieves
  • This War of Mine
  • This Way Madness Lies
  • Three Kingdom: The Journey
  • Time on Frog Island
  • Tinkertown
  • Tiny Tina’s Wonderland(EU)
  • TINY TINA'S WONDERLANDS CHAOTIC GREAT EDITION
  • Tiny Troopers
  • Tinykin
  • Tinytopia
  • TIS-100
  • Titan Quest
  • Tokyo Xanadu eX+
  • Tom Clancy's The Division™
  • Tom Clancy's The Division™ - Survival!
  • Tools up
  • Tooth and Tail
  • Torchlight
  • Total Tank Simulator
  • Tour de France 2020
  • Tower Unite
  • Townsmen - A kingdom Rebuilt
  • Trail Out
  • Trailblazers
  • Trailmakers
  • Trailmakers Deluxe Edition
  • Train Sim World 3: Standard Edition
  • Train Simulator Classic
  • Train Valley 1
  • Transport INC
  • Treasure Hunter Simulator
  • TRIBES OF MIDGARD
  • Trine 4: The Nightmare Prince
  • Trinity Fusion
  • Trombone Champ
  • Tropico 5 - Complete Collection
  • Trover Saves the Universe
  • Tunche
  • Turmoil
  • Turok 2: Seeds of Evil
  • Twin Mirror
  • Two Point Campus
  • Two Point Hospital
  • TYPECAST
  • Tyrant's Blessing
  • Ultimate Chicken Horse
  • Ultimate Zombie Defense
  • Ultra Space Battle Brawl
  • Unavowed
  • Undead Horde
  • Underhero
  • Unexplored 2: The Wayfarer's Legacy
  • Unity of Command: Stalingrad Campaign
  • Universim
  • UNLOVED
  • Unpacking
  • Until I have you
  • Unto The End
  • Upside Down
  • URU: Complete Chronicles
  • Vagante
  • Valfaris
  • Valfaris: Mecha Therion
  • Valkryia Chronicles 4 Complete Edition
  • Valkyria Chronicles 4 Complete Edition
  • Valkyria Chronicles 4: Complete Edition
  • Vambrace: Cold Soul
  • Vampire - The Masquerade: Shadows of New York
  • Vampire Survivors
  • Vane
  • Vectronom
  • Velocity Noodle
  • Venba
  • Verne: The Shape of Fantasy
  • Victoria 3
  • Victoria II
  • Viking: Battle For Asgard
  • Virgo Versus The Zodiac
  • VirtuaVerse
  • Visage
  • Viscerafest
  • Void Bastards
  • VOIDIGO
  • Volcanoids
  • Voltage High Society
  • V-Rally 4
  • Wanderlust: Travel Stories (GOG)
  • Wanted: Dead
  • Wargroove
  • Warhammer 40,000 Sanctus Reach - Complete Edition
  • Warhammer 40,000: Armageddon - Imperium Complete
  • Warhammer 40,000: Battlesector
  • Warhammer 40,000: Gladius - Relics of War
  • Warhammer 40,000: Mechanicus
  • Warhammer 40,000: Space Wolf Special Edition
  • WARHAMMER AGE OF SIGMAR: REALMS OF RUIN – ULTIMATE EDITION
  • Warhammer vermintide collector's edition
  • Warhammer: End Times - Vermintide
  • Warhammer: Vermintide 2
  • Warman
  • Warstone TD
  • Wasteland 3
  • Wayward
  • WE NEED TO GO DEEPER
  • We should talk.
  • We Were Here Together
  • We Were Here Too
  • Webbed
  • Werewolf: The Apocalypse Heart of the Forest
  • West of Dead
  • What Lies in the Multiverse
  • When Ski Lifts Go Wrong
  • while True: learn()
  • Whos Your daddy
  • Wick
  • Windward
  • Witch It
  • Witchy Life Story
  • wizard of legends
  • Wolfenstein 3D
  • Worms Rumble
  • Worms Rumble + Legends Pack
  • Wrath: Aeon of Ruin
  • WRC 6 FIA World Rally Championship
  • WRC 7 FIA World Rally Championship
  • WWE 2K Battlegrounds
  • WWE 2K23
  • WWZ Aftermath
  • Wytchwood
  • X-COM: COMPLETE PACK
  • XCOM: ULTIMATE COLLECTION
  • XIII - Classic
  • X-Morph: Defense
  • X-Morph: Defense + European Assault, Survival of the Fittest, and Last Bastion DLC
  • X-Morph: Defense Complete Pack
  • Yakuza Kiwami
  • Yakuza: Like A Dragon
  • Yumeutsutsu Re:After
  • Yumeutsutsu Re:Master
  • Zen Chess: Mate in One, Mate in 2 , Mate in 3 , Mate in 4 , Champion's Moves (5 games)
  • Ziggurat
  • Zombie Army 4
  • Zombie Army Trilogy
  • Zool Redimensioned
  • Zwei: The Arges adventure
  • Zwei: The ilvard insurrection
DLCs and Softwares:
  • For The King: Lost Civilization Adventure Pack
  • Train Simulator: Isle of Wight Route Add-On
  • Train Simulator: Woodhead Electric Railway in Blue Route Add-On
  • Train Simulator: North Somerset Railway Route Add-On
  • Train Simulator: Union Pacific Heritage SD70ACes Loco Add-On
  • Train Simulator: London to Brighton Route Add-On
  • BR Class 170 'Turbostar' DMU Add-On
  • DB BR 648 Loco Add-On
  • Europa Universalis IV: Wealth of Nations
  • Expansion - Europa Universalis IV: Conquest of Paradise
  • Expansion - Europa Universalis IV: Res Publica
  • Grand Central Class 180 'Adelante' DMU Add-On
  • Peninsula Corridor: San Francisco - Gilroy Route Add-On
  • SONIC ADVENTURE 2: BATTLE
  • Small World - A Spider's Web
  • Small World - Cursed
  • Small World - Royal Bonus
  • The Dungeon Of Naheulbeuk: The Amulet Of Chaos - Goodies Pack
  • The Dungeon Of Naheulbeuk: The Amulet Of Chaos - OST
  • Thompson Class B1 Loco Add-On
  • Total War: Shogun 2 - Rise of the Samurai
  • Train Sim World® 3: Birmingham Cross-city line
  • Train Sim World®: BR Class 20 'Chopper' Loco
  • Train Sim World®: Brighton Main Line: London Victoria - Brighton
  • Train Sim World®: Caltrain MP36PH-3C 'Baby Bullet'
  • Train Sim World®: Cathcart Circle Line: Glasgow - Newton & Neilston
  • Train Sim World®: Clinchfield Railroad: Elkhorn - Dante
  • Train Sim World®: Great Western Express
  • Train Sim World®: Hauptstrecke Hamburg - Lubeck
  • Train Sim World®: LIRR M3 EMU
  • Train Sim World®: Long Island Rail Road: New York - Hicksville
  • Train Sim World®: Nahverkehr Dresden - Riesa
  • Train Sim World®: Northern Trans-Pennine: Manchester - Leeds
  • Train Sim World®: Peninsula Corridor: San Francisco - San Jose
  • Train Sim World®: Rhein-Ruhr Osten: Wuppertal - Hagen
  • Train Sim World®: Tees Valley Line: Darlington - Saltburn-by-the-sea
  • Worms Rumble - Armageddon Weapon Skin Pack
  • Worms Rumble - Captain & Shark Double Pack
  • Worms Rumble - Legends Pack
  • Worms Rumble - New Challengers Pack
  • Ashampoo Photo Optimizer 7
  • Dagon: by H. P. Lovecraft - The Eldritch Box DLC
  • Duke Nukem Forever Hail to the Icons
  • Duke Nukem Forever The Doctor Who Cloned Me
  • GRIP: Combat Racing - Cygon Garage Kit
  • GRIP: Combat Racing - Nyvoss Garage Kit
  • GRIP: Combat Racing - Terra Garage Kit
  • GRIP: Combat Racing - Vintek Garage Kit
  • GameGuru
  • GameMaker Studio 2 Creator 12 Months
  • Intro to Game Development with Unity
  • Music Maker EDM Edition
  • Neverwinter Nights: Darkness Over Daggerford
  • Neverwinter Nights: Enhanced Edition Dark Dreams of Furiae
  • Neverwinter Nights: Enhanced Edition Tyrants of the Moonsea
  • Neverwinter Nights: Enhanced Edition
  • Neverwinter Nights: Infinite Dungeons
  • Neverwinter Nights: Pirates of the Sword Coast
  • Neverwinter Nights: Wyvern Crown of Cormyr
  • PDF-Suite 1 Year License
  • Pathfinder Second Edition Core Rulebook and Starfinder Core Rulebook
  • RPG Maker VX
  • WWE 2K BATTLEGROUNDS - Ultimate Brawlers Pass
  • We Are Alright
  • The Outer Worlds Expansion Pass
  • A Hat in Time - Seal the Deal DLC
  • City Skylines:mass transit
  • A Game Of Thrones - A Dance With Dragons
  • A Game Of Thrones - A Feast For Crows
  • Blood Rage: Digital Edition - Gods of Asgard
  • Blood Rage: Digital Edition - Mythical Monsters
  • Blood Rage: Digital Edition - Mystics of Midgard
  • Carcassonne - The Princess and The Dragon DLC
  • Carcassonne - Traders & Builders DLC
  • Carcassonne - Winter & Gingerbread Man DLC
  • Carcassonne - Inns & Cathedrals
  • Carcassonne - The River
  • Splendor: The Trading Posts DLC
  • Splendor: The Strongholds DLC
  • Splendor: The Cities DLC
  • Small World - Be Not Afraid... DLC
  • Small World - Grand Dames DLC
  • Small World - Cursed!
  • Sands of Salzaar - The Ember Saga
  • Sands of Salzaar - The Tournament
  • Monster Train: The Last Divinity DLC
  • WARSAW
submitted by calvin324hk to indiegameswap [link] [comments]


2024.05.29 00:18 calvin324hk [H] 1000+ Games / DLCs / VR Games [W] Paypal / Wishlist / Offers

https://www.reddit.com/IGSRep/comments/pikmri/calvin324hks_igs_rep_page/
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Wishlist
Region: NA (Canada)
Fees on buyer if any, currency is USD unless specified
CTRL + F to find your games in terms of name
  • 10 Second Ninja X
  • 11-11 Memories Retold
  • 112 Operator
  • 12 is Better Than 6
  • 198X
  • 1993 Space Machine
  • 60 Parsecs
  • 7 Billion Humans
  • 8 DOORS
  • 8-bit Adventure Anthology: Volume I
  • 9 Years of Shadows
  • 911 Operator
  • A Game of Thrones: The Board Game
  • A Hat in Time
  • A Hole New World
  • A JUGGLER'S TALE
  • A Long Way Down
  • A PLAGUE TALE: INNOCENCE
  • A Robot Named Fight!
  • A Tale for Anna
  • A.I.M.2 Clan Wars
  • Abalon (Summoners Fate)
  • Above Snakes
  • ABZU
  • Ace Combat Assault Horizon Enhanced Edition
  • ADOM
  • Adore
  • Aegis Defenders
  • Aeterna Noctis
  • AETHERIS
  • Agatha Christie Hercule Poirot The First Cases
  • AIdol
  • Airborne Kingdom
  • Alba: A Wildlife Adventure
  • Alder's Blood: Definitive Edition
  • Alfred Hitchcock - Vertigo
  • Alien Breed Trilogy
  • Aliens vs. Predator™ Collection
  • All-Star Fruit Racing
  • Almost There: The Platformer
  • American Fugitive
  • American Truck Simulator
  • Amerzone: The Explorer’s Legacy
  • AMID EVIL
  • Amnesia rebirth
  • Amnesia: The Dark Descent + Amnesia: A Machine for Pigs
  • Anomalous
  • Another World – 20th Anniversary Edition
  • Antigraviator
  • Anuchard
  • APICO
  • APICO
  • Aragami
  • Aragami 2
  • Arboria
  • Arcade Paradise
  • Arcade Paradise - Arcade Paradise EP
  • Arcade Spirits
  • Arkham Horror: Mother's Embrace
  • Armada 2526 Gold Edition
  • Army Men RTS
  • army of ruin
  • Arto
  • Ary and the Secret of Seasons
  • As Far as the Eye
  • Ascension to the Throne
  • Assemble With Care
  • Assetto Corsa Competizione
  • Assetto Corsa Ultimate Edition
  • Astebreed Definitive Edition
  • Astro Colony
  • Astronarch
  • Attack of the Earthlings
  • Automachef
  • Automobilista
  • Automobilista 2
  • AUTONAUTS
  • AUTONAUTS VS PIRATEBOTS
  • Avatar: Frontiers of Pandora™ - Ubisoft Connect
  • AVICII Invector: Encore Edition
  • Awesomenauts All Nauts pack
  • Axiom Verge
  • Axiom Verge 2
  • Baba is you
  • Back 4 Blood
  • Back 4 blood (EU)
  • Backbone
  • Baldur's Gate II: Enhanced Edition
  • Baldur's Gate: Enhanced Edition
  • Banners of Ruin
  • Bartlow's Dread Machine
  • Basement
  • Batbarian: Testament of the Primordials
  • Batman: Arkham Asylum Game of the Year Edition
  • Batman: Arkham Origins
  • Battle Royale Tycoon
  • Battlecruisers
  • Battlestar Galactica Deadlock
  • BATTLESTAR GALACTICA DEADLOCK SEASON ONE
  • Battlestar Galactica Deadlock: Complete
  • BATTLETECH MERCENARY COLLECTION
  • BATTLETECH Shadow Hawk Pack
  • BEAUTIFUL DESOLATION
  • Bee Simulator
  • BEFORE WE LEAVE
  • Beholder 2
  • Ben 10
  • Ben 10: Power Trip
  • Bendy and the Ink Machine™
  • Between the Stars
  • Beyond a Steel Sky
  • Beyond The Edge Of Owlsgard
  • BEYOND THE WIRE
  • Beyond: Two Souls
  • BIOMUTANT
  • Bionic Commando
  • Bionic Commando Rearmed
  • BioShock: The Collection
  • BLACK BOOK
  • Black Moon Chronicles
  • Black Paradox
  • BLACK SKYLANDS
  • BLACKHOLE: Complete Edition
  • Blacksad: Under the Skin
  • Blade of Darkness
  • Blasphemous
  • Blazing Chrome
  • Blightbound
  • Blood And Zombies
  • Blood Rage: Digital Edition
  • Bloodstained: Ritual of the Night
  • Blue Fire
  • Bomber Crew
  • Boneless Zombie
  • Boomerang Fu
  • Borderlands 3
  • Borderlands 3 Super Deluxe
  • Borderlands 3 Super Deluxe Edition
  • Borderlands: The Handsome Collection
  • Bot Vice
  • Bounty of One
  • Brawlout
  • Breakout: Recharged
  • Breathedge
  • bridge constructor
  • Bridge constructor medieval
  • bridge constructor stunts
  • Broken Lines
  • Brothers: A Tale of Two Sons
  • Brutal Legend
  • Bug Fables: The Everlasting Sapling
  • BUILDER SIMULATOR
  • calico
  • Call of Duty® Modern Warfare 3™ (2011)
  • Call of Juarez: Gunslinger
  • Capitalism 2
  • Car Mechanic 2018
  • Car Mechanic Simulator 2015
  • Car Mechanic Simulator 2018
  • Cardboard Town
  • Castle Morihisa
  • castle storm
  • CastleStorm
  • Cat Cafe Manager
  • Catherine Classic
  • Caveblazers
  • Celeste
  • Centipede: Recharged
  • Cepheus Protocol
  • CHANGE: A Homeless Survival Experience
  • Charlie's Adventure
  • Chenso Club
  • Chernobylite: Enhanced Edition
  • Chess Ultra
  • Chicago 1930 : The Prohibition
  • Chivalry 2
  • Chop Goblins
  • Chorus
  • Chorus
  • Circuit Superstars
  • Cities Skylines + After Dark
  • Cities: Skylines
  • City of Beats
  • CivCity: Rome
  • Click and Slay
  • Cloud Gardens
  • Cloudpunk
  • Code Vein
  • Coffee Talk
  • Comedy Night
  • Command & Conquer Remastered (Origin)
  • Complete Dread X Collection
  • Conarium
  • Construction Simulator (2015) Deluxe Edition
  • Constructor Plus
  • Control
  • Cook, Serve, Delicious! 3
  • Cook, Serve, Delicious! 3?!
  • Cookie Cutter
  • cornucopia
  • Corridor Z
  • Cosmic Osmo and the Worlds Beyond the Mackerel
  • Cosmonautica
  • Crash Drive 2
  • Crash Drive 3
  • Creaks
  • Creepy Tale
  • Crookz the big heist
  • CROSSBOW: Bloodnight
  • Crush Your Enemies
  • Cube Runner
  • Cultist Simulator: Anthology Edition
  • Curse: The Eye of Isis
  • Cyber Ops
  • Cybercube
  • Danger Scavenger
  • Dark Deity
  • Dark Future
  • DARK PICTURES ANTHOLOGY: HOUSE OF ASHES
  • Darkwood
  • DARQ: Complete Edition
  • Day of the Tentacle Remastered
  • days of war definitive edition
  • Dead by Daylight
  • Dead Estate
  • Dead Rising 2
  • Deadly Days
  • Dear Esther: Landmark Edition
  • DEATH STRANDING DIRECTOR'S CUT
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  • The Battle of Polytopia
  • The Battle of Polytopia *DLC1. Cymanti Tribe *DLC2. ∑∫ỹriȱŋ Tribe *DLC3. Aquarion Tribe *DLC4. Polaris Tribe
  • The Beast inside
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  • The Darkest Tales
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  • The Dungeon of Naheulbeuk: The Amulet of Chaos
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  • THE PALE BEYOND
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  • The Uncertain: Light At The End
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  • The Walking Dead
  • The Walking Dead - 400 Days
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  • The Walking Dead: Final Season
  • The Walking Dead: Michonne - A Telltale Miniseries
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  • The Walking Dead: Season 1
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  • The Way
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  • Thief of Thieves
  • This War of Mine
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  • Three Kingdom: The Journey
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  • TINY TINA'S WONDERLANDS CHAOTIC GREAT EDITION
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  • Tools up
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  • Universim
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  • Unpacking
  • Until I have you
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DLCs and Softwares:
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submitted by calvin324hk to SteamGameSwap [link] [comments]


2024.05.28 22:53 Phulekillz About time for another lackluster patch to boost the numbers for a week. About to dip below 800 concurrent again.

About time for another lackluster patch to boost the numbers for a week. About to dip below 800 concurrent again. submitted by Phulekillz to MortalOnline [link] [comments]


2024.05.28 22:50 Jadeddreamer_ Help/advice on grief for family

So l (21 F) and my sister (24 F) both lost our mom (54) to stage 4 pancreatic cancer back in November. Our mom was placed hospice care and died at home. Growing up, i had often struggled with hygiene (and in some cases still do) and overall cleanliness as I'm autistic and ADHD and have bad anxiety but i eventually learned those traits myself. Also growing up my parents struggled with cleaning and doing household chores, not because they were both lazy, but because of the fact they both had health issues my dad (heart disease, low blood pressure, diabetic) my mother also had heart disease and also before her pancreatic cancer she also had stage 3 breast cancer as well in 2013. Household chores /cleaning often became a "do it when you can" type of way. Also when my mom got sicker as well her room became kind of like a hoarders room and has been a struggle for all of us to sort through even months after her passing.
Since my mom has died, me, my dad and my sister all have our ways of coping. My sisters in particular has been excessively cleaning. At first it used to be an every other day thing but now it's gotten to be everyday. I even ask her if i can help her take off some of the pressure as well even if i can't multitask as well as she can because of my autism and adhd (our dad has been taking care of my grandmother who's disabled and had surgery right after my mom passed and has been at her house for 2 months while working a full time remote job after months of being in and out of the cancer hospital with my mother. My dad is kind of unreachable at the moment). If i try to help my sister with the cleaning she wants things a certain way and i will ask for clarity, she will "correct" it, she will take her anger out of me (not physically but verbally). I sometimes will ask my dad to talk to her to go easy on me since i am trying my best to help her and because of her cleaning and me trying to help it's caused fights, screaming matches, and me with more anxiety /panic attacks. I always feel like no matter how hard i tried nothing is good enough. I even reccomended seeing a grief counselor for the family and they all agreed but every time i mention it, it gets hold back. Anyone have any advice? because this is getting mentally and physically draining.
Also edit : another reason why my sister and i are always cleaning the house is because we got a Frenchie puppy as well a month after my mom passed (it was my sister's idea) to help us with my mom's passing. And i love my dog, he's a good emotional support system but i know the house at this rate the house will never be spotless clean because he (my dog) sheds a lot and his toys, chewies, and blankets he snuggles with are always everywhere and even if you do clean up after him he is like a little kid and will go back and put them back on the floor.
submitted by Jadeddreamer_ to Advice [link] [comments]


2024.05.28 21:50 Jadeddreamer_ Does anyone know how to deal with someone’s way of grieving?

So I (21 F) and my sister (24 F) both lost our mom (54) to stage 4 pancreatic cancer back in November. Our mom was placed hospice care and died at home. Growing up, i had often struggled with hygiene (and in some cases still do) and overall cleanliness as I’m autistic and ADHD and have bad anxiety but i eventually learned those traits myself. Also growing up my parents struggled with cleaning and doing household chores, not because they were both lazy, but because of the fact they both had health issues my dad (heart disease, low blood pressure, diabetic) my mother also had heart disease and also before her pancreatic cancer she also had stage 3 breast cancer as well in 2013. Household chores /cleaning often became a “do it when you can” type of way. Also when my mom got sicker as well her room became kind of like a hoarders room and has been a struggle for all of us to sort through even months after her passing.
Since my mom has died, me, my dad and my sister all have our ways of coping. My sisters in particular has been excessively cleaning. At first it used to be an every other day thing but now it’s gotten to be everyday. I even ask her if i can help her take off some of the pressure as well even if i can’t multitask as well as she can because of my autism and adhd (our dad has been taking care of my grandmother who’s disabled and had surgery right after my mom passed and has been at her house for 2 months while working a full time remote job after months of being in and out of the cancer hospital with my mother. My dad is kind of unreachable at the moment). If i try to help my sister with the cleaning she wants things a certain way and i will ask for clarity, she will “correct” it, she will take her anger out of me (not physically but verbally). I sometimes will ask my dad to talk to her to go easy on me since i am trying my best to help her and because of her cleaning and me trying to help it’s caused fights, screaming matches, and me with more anxiety /panic attacks. I always feel like no matter how hard i tried nothing is good enough. I even reccomended seeing a grief counselor for the family and they all agreed but every time i mention it, it gets hold back. Anyone have any advice? because this is getting mentally and physically draining.
Also edit : another reason why my sister is always cleaning the house is because we got a Frenchie puppy as well a month after my mom passed (it was my sister’s idea) to help us with my mom's passing. And i love my dog, he's a good emotional support system but i know the house at this rate the house will never be spotless clean because he (my dog) sheds a lot and his toys, chewies, and blankets he snuggles with are always everywhere and even if you do clean up after him he is like a little kid and will go back and put them back on the floor.
submitted by Jadeddreamer_ to GriefSupport [link] [comments]


2024.05.28 21:19 Background-Today-486 Old guy with 10 year history of ET

Have been meaning to add this for some time. but to lazy I guess. I have been diagnosed with ET for about 10 years ( I am currently 88). I have seen one of the hospitals that performs the non invasive procedure to stop ET. I drew the circles and was told that my case was really not sufficiently severe enough to take the risk. At that time the procedure was very expensive (as I recall about $10,000) with no medicare coverage and about a 5 % mortality rate. I have lived with the problem. I take 3 Primidone tabs of 250MG each. Morning, noon and night. together with 1 tablet of Gabapentin 300 MG. This combination makes it so that MOST days I can read my own writing but not always. like others on the group, you do not want to be setting next to me if we are having soup. I do take other meds and I do take a puff of weed on occasion. I do take other meds for non ET problems
submitted by Background-Today-486 to EssentialTremor [link] [comments]


2024.05.28 17:49 Remarkable-Effort301 PT: Mysophobia- how can I get rid of it or at least reduce the exaggerated uneasiness towards germs

I am 32 years old now and for more than 15 years the level of uneasiness towards certain types of dirt or potential infection through germs has grown to a level that already is annoying for others, to say the least, if not even in parts has become influential/manipulative for my behavior towards my SO :/
This is my situation and I am seeking for advice on how to destruct this anxiety which controls in large parts how I am thinking and going through everyday life.
If you read all of it, you might be able to outline that this fear mostly applies to the invisible dangers sitting somewhere to take away from my health, this makes it even more difficult for me to tackle the problem!
An example for how high the level of irrational thinking has grown during the time I was most affected by this unnatural behavior: Pretending almost the “floor is lava “ only that it already made me uneasy when something like a pillow from the couch or my shirt, my jacket, or a cosmetic container fell down to the floor of the Sorensen apartment I was living in..afraid that it could have touched infectious germs a (while fighting a skin infection in the best way possible-it literally made me crazy x(( )
Also, it might be helpful to mention that I was diagnosed with an autoimmune disease in 2017, which in itself - although being heritable- might have become active / “broke out” as a comorbidity of being chronically stressed.
•The underlying reason for this could have been AD(H)D symptoms that went unnoticed since childhood but intensified/ got worse over the last years especially
= when anxiety intensified =
A big marker that intensified the situation definitely has been the time around COVID lockdown, where a fear of germs has become more socially acceptable.
(But even before I had and still have a heightened sense of trying to keep up the level of cleanliness)
As most people who „played the game“ of integrating higher hygiene measurements for the sake of their own health and trying to find back into the reality they were led by before, I tried to do the same: By gradually reducing the precautions like using hand sanitizer on a regular basis and wearing masks.
..With the exception that I carry a spray bottle of hand sanitizer with me at most times when being outside, in one way or another (gel instead of spray) already since school days when I was about 15 maybe. Before that, I carried my own liquid soap miniature in case there was none in the restrooms at school (in elementary school already!)
= Skin infection issues = (further elaboration in the comments)
I fought hard against a fungal skin infection on my feet for about five years with shorter periods of seemingly being cured for some months before having to deal with it again and keeping up a disciplined hygiene routine to make sure it will go and stay away.
My treatment to get rid of it was washing/treating my feet every evening, and blowing out my shoes with hot air regularly, also washing the bed sheets on higher temperature than normal.
This regiment, especially the tedious evening routine of putting on clean socks, the pre- and post-action was successful.
But although my feet are healthy now, there is fear in everyday and special occasions that makes me act differently to how you’d expect anybody else to react, because I am precautious and trying to avoid getting an infection again by any means!
(Since this time really wrecked my sanity as there didn’t seem to be a cure for me over the course of 5 years)
So what remains as a low-energy effort to stay away from reinfection is •wearing socks at all times (working on that already)
•Collecting my worn socks separately and pretreating them with laundry sanitizer before I put them in the machine
•a huge fear of risking an infection in humid places of public facilities (showers of gyms and indoor swimming pools..and of course hotel rooms always doubting the efficiency of keeping their rooms clean, may it be the bath and shower itself or the remaining furniture and carpets in the room.
(That is why when having to stay at a hotel I try to choose rooms without carpets and avoid using the shower if possible. In case I use them, I’d prefer to prepare the floor of the shower by using alcohol-based hygiene spray first and then showering with slippers on, just in case.)
•I have no problem with going for a swim in natural environments where there is only sand to get rid of. So this way of taking a bath is okay, while on the other hand, I still fear taking a relaxing foot bath or when using the tub, keeping my feet under water for extended periods until my skin would get soggy because I am really afraid that potential germs could enter in case there might be small injuries to the skin.
=My Dad’s suffering/ the Trauma involved=
On another note, what might have made me more prone to mysophobia is the time when my father got ill and was diagnosed with cancer, later died from the side effects of the treatment.
The cortisone treatment made him suffer from extreme itching, red and thinning skin, scaling was an issue which I guess also made me more sensible to being afraid of uncleanliness (Shaming myself until today for being afraid of closeness towards my dad in these times)
In the hospital he caught an infection with multi-resistant bacteria. So I learned that it is a condition you can have without noticing which mostly becomes critical in hospital environments or for people whose immune system is weakened..
Apart from that, I understood it is an invisible danger which can survive several months on surfaces and personal objects.
…..If you were strong enough to make it til here and fought through this jungle of my described fear of germs, congratulations- I am so thankful for any advice you might want to share!….
submitted by Remarkable-Effort301 to germaphobe [link] [comments]


2024.05.28 14:01 bvlich Background: Centrifugal-flow left ventricular assist devices (CF-LVADs) have improved morbidity and mortality for their recipients. Hospital readmissions remain common, negatively impacting quality of life and survival.

Background: Centrifugal-flow left ventricular assist devices (CF-LVADs) have improved morbidity and mortality for their recipients. Hospital readmissions remain common, negatively impacting quality of life and survival. submitted by bvlich to iperfusion [link] [comments]


2024.05.28 13:42 hffvjjtfthhhj BLASPHEMICAL LIES ON MY PAST, PRESENCE AND FUTURE. I SERVE THE ELDER AUTHORITIES SINCE YOUTH TRUSTWORTHY AND MORALLY, CONFIRMED. b) I NEVER MISTREATED HUMAN MORTAL REMAINS IN LIFE, HAVING ACCOMPANIED THEIR PASSAGE AT HOSPITAL IN ABOUT 9X-1XX CASES MORALLY. NOT I UNCOVERED A DEAD PERSON EVER!

NOT I UNCOVERED DEAD PERSON! NOT I DECLARED TO KILL; DISEMBOWELL AND ORGAN.SELL (THIS GOLLUM BEAST SERIOUSLY WILL DIE SOON IN TIME///
IT IS FALSE DECLARATION THAT I WOULD NEVER BECOME RECEIVE A BURIAL OR LAST REST. WARNING. NO CROSS! MY FAMILY'S HUMAN MORTAL ReMAINS ARE NOT TO BE MUTILATED. WARNING!
NO FILM RECORDINGS. COLPORTED "sie macht nun den DREH!" BReAK THIS WHORE'S NECK? BRECHEN SIE DER KAPITALSTRAFTÄTERIN UNBEFUGTEN FILMTERRORISTIN DAS GENICK. #
FORWARD CIA.GOV IDENTIFY AND KILL THIS BEAST. RIGHT ON OWN IMAGE. KILL THIS SNUFF CHILDPORNOGRAPHERS!
PS) TRACE AND DESTROY THESE GERMAN BEASTS.
US CIA 7AGSXU2X
\
submitted by hffvjjtfthhhj to u/hffvjjtfthhhj [link] [comments]


2024.05.28 13:37 emy8087 How is poona hospital ? Or should i look for other options.

I need to take my mother for surgery . Doctor has asked for a admission for two days. I want to know should i prefer this hospital for treatment or should i look for other ones like sahyadri ?
Things which concern me is the cleanliness , supporting staff , room conditions , money and overall experience . Have any of you been in poona hospital for admission or any opd !??
submitted by emy8087 to pune [link] [comments]


2024.05.28 13:00 bvlich Background: Centrifugal-flow left ventricular assist devices (CF-LVADs) have improved morbidity and mortality for their recipients. Hospital readmissions remain common, negatively impacting quality of life and survival.

Background: Centrifugal-flow left ventricular assist devices (CF-LVADs) have improved morbidity and mortality for their recipients. Hospital readmissions remain common, negatively impacting quality of life and survival. submitted by bvlich to iperfusion [link] [comments]


2024.05.28 10:35 digicat Hacked to Pieces? The Effects of Ransomware Attacks on Hospitals and Patients - from Oct 23 - "In-hospital mortality for patients already hospitalized at a ransomware-attacked hospital increases between 1.28 and 1.87% – representing a 35.9-55.3% relative increase when compared to pre-attack mean"

submitted by digicat to blueteamsec [link] [comments]


2024.05.28 09:41 ghostsaresleeping Shock 5/28

The Hermes cabin was extremely crowded. It took forever to find a bed that wasn't being used. Naomi enjoyed socializing, but she hated feeling cramped. She especially hated knowing that she didn't belong there. Hermes wasn't her dad. Her father was mortal, and he claimed her mother was a goddess.
Before she ran away, her parents had sat her down and explained that her mom wasn't really her mom. The woman who had loved and raised Naomi for her entire life was actually her stepmother. Naomi's dad explained that her real mother was a goddess, and he gave her a Celestial bronze flute, saying it was actually a weapon she could use to destroy monsters. Apparently her (goddess) mother had wanted her to have it.
Naomi insisted they had both lost their minds. Terry was her real mom. There was something wrong with them. She lasted three more months, saving her weekly allowance and stowing away non-perishable food, snacks, and bottles of water. It was difficult waiting until summer break, but she wanted to finish out the year before she left. That way none of her friends would be suspicious (she never skipped school). But then her parents started talking about protecting her from monsters, and they were scaring her. She was scared for their mental health, but she was 13, she couldn't exactly call a hospital and have them committed. She couldn't do anything but leave, and she finally did, on March 21, when her parents were sleeping.
For 4 months, Naomi lived on the street. No goddess showed up to claim her. No monsters ever attacked. Her parents were so worried that would happen, yet she didn't see any at all. That was one of the last things her father mentioned before Naomi couldn't bear any more goddess talk. So much about monsters and how she should be ready for them.
The night before she arrived at camp, Naomi was camping at Lake Montauk. She'd bought a tent with the money she saved and carried it everywhere. The sounds of shuffling and snorting woke her up, and she saw the shadow of a giant dog outside.
That was when she used her flute for the first time. By pressing the notes in a certain sequence, she activated the weapon. The flute transformed into a Celestial bronze morning star with a chain as long as her arm. She'd managed to blind the beast in one eye before running away, but it caught up to her again at the base of Half-Blood Hill. It gave her a shallow scratch on her stomach, tearing her shirt in the process. Using the morning star, she blinded its other eye and managed to get past the border while the monster howled.
For two days, Naomi had been in a state of shock, wandering around camp in a daze, unable to believe in what she was seeing. She didn't want to admit that her father was right. She didn't want any of this to be real. She wanted to wake up and be back home, experiencing her frustrating but otherwise normal life. But in two days, that still hadn't happened.
She wandered down to the lake and sat on the dock, staring out at the deceptively calm water.
submitted by ghostsaresleeping to CampHalfBloodRP [link] [comments]


2024.05.28 05:14 AbeVigoda76 Secret Service Agent Tim McCarthy takes a bullet for President Ronald Reagan, March 30th, 1981

Secret Service Agent Tim McCarthy takes a bullet for President Ronald Reagan, March 30th, 1981
In this photo, Special Agent Tim McCarthy stretches his body out to shield President Reagan who is being placed in the car by Agent Jerry Parr directly behind McCarthy.Seconds after this photo was taken, McCarthy was shot in the chest. Tim McCarthy was not supposed to be at work that day and only came in because he lost a coin toss with another agent. As of 2024, McCarthy is still alive and worked in law enforcement until 2020.
Tim McCarthy is one of only two secret service personnel to take a bullet for the president. The other was a uniformed officer named Leslie Coffelt who was ambushed in his guard booth shot three times in the chest and the abdomen. Despite being mortally wounded, Coffelt climbed out of his booth and shot one of the attempted assassins dead before collapsing and eventually succumbing to his wounds in the hospital.
submitted by AbeVigoda76 to OldSchoolCool [link] [comments]


2024.05.28 03:12 ricotito23 [USA-PR] [H] Switch,PS2,PS4,PS5,Vita,3DS Games [W] PayPal

Selling my personal collection. Over 800 Games.
Sorry my bad english. Paypal ff.
Free Shipping over $100. More photos at request. Offers are welcome. Most of these Prices are based on Pricharting (and pricecharting price are inaccurate so sorry im lazy to put my prices for these 800 games) Offers are welcome Worst can say is no.There's a problem with letter T jumps to C in switch and vita to A. working on it. Also i have blaster master and shantae slipcovers. Want to sell them together with Slipcovers.
https://imgur.com/a/ntp4d6Q
Nintendo Switch
13 Sentinels: Aegis Rim CIB+ 32.92
1971 Project Helios New 15.41
Boy and His Blob New 50.49
Little Golf Journey New 29.62
Robot Named Fight [Premium Edition] New 50.5
Adventure Time: Pirates of the Enchiridion New 25.68
AeternoBlade II New 35.5
Afterparty New 38
Aggelos New 38.22
AI: The Somnium Files CIB+ 60.5
Alex Kidd in Miracle World DX New 18.98
Alwa's Collection New 25.62
American Hero New 40.49
Ancestors Legacy New 24.07
Annapurna Interactive [Deluxe Limited Edition Collection] New 230.00
Ape Out [Special Reserve] New 40.00
Ara Fell & Rise of the Third Power New 57.24
Arcade Spirits New 20
Archvale New 51.25
ARMS CIB+ 30.5
Ary and the Secret of Seasons New 12.52
Arzette: The Jewel of Faramore New 55.00
Assassin's Creed: The Rebel Collection CIB+ 17.48
Astalon: Tears of the Earth New 50.63
Astral Chain New 48.99
Astronite New 19.48
Atelier Ryza 2: Lost Legends & the Secret Fairy New 55.00
Atelier Ryza: Ever Darkness and the Secret Hideout CIB+ 49.5
Atelier Ryza: Ever Darkness and the Secret Hideout New 60.1
Attack on Titan 2: Final Battle New 65.00
Azure Striker Gunvolt 3 New 48.5
Azure Striker Gunvolt: Striker Pack CIB+ 25.79
Balan Wonderworld New 11.77
Baldur's Gate and Baldur's Gate II: Enhanced Editions New 120.00
Battle Chef Brigade Deluxe CIB+ 32.61
Battle Princess Madelyn: Royal Edition New 52.88
Black Bird New 55.5
Blade Runner: Enhanced Edition New 48.72
Blasphemous CIB+ 108.49
Blaster Master Zero New 44.14
Blaster Master Zero II New 40.49
Blaster Master Zero III New 34.5
Blazing Beaks New 30.02
Blazing Chrome CIB+ 65.92
Bloodrayne 1 & 2: Revamped Dual Pack w/ Slipcover New 100.47
BloodRayne Betrayal: Fresh Bites New 40.49
Bloodstained: Curse Of The Moon 2 New 28.49
Bloodstained: Ritual of the Night New 21.23
Blossom Tales II: The Minotaur Prince New 46.48
Blossom Tales: The Sleeping King CIB+ 150.47
Blue Fire CIB+ 28.49
Blue Reflection: Second Light New 59.83
Bomb Chicken CIB+ 38.14
BROFORCE [SWITCH RESERVE] New 40.00
Bug Fables: The Everlasting Sapling New 55.93
Bugsnax CIB+ 30.77
Burnout Paradise Remastered CIB+ 14.98
BUTCHER New 36.9
Cannon Dancer: Osman New 54
Captain Toad: Treasure Tracker CIB+ 30.49
Captain Tsubasa: Rise of New Champions New 26.09
Card Shark Collector's Edition New 40.00
Carrion: Special Reserve Edition New 40.00
Castlevania Anniversary Collection New 40.00
Cat Girl Without Salad: Amuse-Bouche New 40.97
Cat Quest + Cat Quest II: Pawsome Pack New 49.5
Cathedral New 66.91
Celeste New 62.39
Chicken Police - Paint it RED! CIB+ 13.25
Children of Morta CIB+ 22.09
Children of Zodiarcs New 44.77
Citizens Unite! Earth X Space New 29.49
Coffee Talk New 42.15
COGEN: Sword of Rewind & Gunvolt Chronicles: Luminous Avenger iX 2 Double Pack New 80.48
Collar X Malice New 30.49
Contra Anniversary Collection New 41.45
Contra Anniversary Collection New 41.45
Cooking Mama: Cookstar New 36.11
Corpse Killer: 25th Anniversary Edition New 42.7
Cosmo Dreamer & Like Dreamer: Double-D Collection New 25.00
Cris Tales New 13.99
Crisis Core: Final Fantasy VII Reunion CIB+ 25
Crossing Souls - Special Reserve New 40.00
Crystal Crisis New 31.52
Cthulhu Saves Christmas New 45.17
Cult of the Lamb [Special Reserve] New 72.48
Dandara: Trials of Fear Edition CIB+ 41.29
Dark Devotion New 45.49
Darksiders Genesis CIB+ 18
Darkwood CIB+ 108.46
DARQ: Complete Edition New 38.97
Dawn of the Monsters New 50.36
Dead Cells: Return to Castlevania Edition New 32.01
Dead or School New 52.03
Deadly Premonition 2: A Blessing in Disguise CIB+ 16.77
Deadly Premonition Origins New 38.03
Death end re;Quest New 41.97
Death Road to Canada New 40
Death's Door [Special Reserve] New 33.03
Death's Gambit: Afterlife New 38.72
Demon Throttle [Reserve Edition] New 25.25
Demon Throttle [Reserve Edition] New 25.25
Demon Turf New 40.82
Demon's Tilt New 44.5
Deponia Collection New 83.14
Dex New 48.38
Digimon Survive New 20.95
Dimension Drive [Limited Edition] New 65.48
Disaster Report 4: Summer Memories CIB+ 25.5
DISC ROOM [SWITCH RESERVE] New 30.00
Disgaea 5 Complete New 39.5
Disney Classic Games: Aladdin and the Lion King New 18.29
Disney Tsum Tsum Festival New 26.55
DISTRAINT Collection New 33.76
Divinity: Original Sin II - Definitive Edition New 180.49
Dodgeball Academia New 19.5
DoDonPachi Resurrection New 55.38
Doki Doki Literature Club Plus! New 20.00
DOOM CIB+ 28.9
Doom 64 New 45.45
DOOM Eternal New 89
DOOM: The Classics Collection New 50.5
Double Dragon & Kunio-Kun Retro Brawler Bundle New 52.83
Double Dragon IV New 33.97
Double Dragon: Neon New 50.49
Downwell [Special Reserve Edition] New 60.00
Double Switch: 25th Anniversary Edition New 55.89
Dragon Ball Z: Kakarot + A New Power Awakens Set Used 25.00
Dragon Quest Treasures New 29.53
Dragon Quest XI S: Echoes of an Elusive Age - Definitive Edition New 40.00
Dragon Star Varnir New 45.49
Dragon's Dogma: Dark Arisen CIB+ 24.74
Dragon's Lair Trilogy New 144.25
DRAINUS New 63.39
Dreamscaper New 44.72
Dusk New 44.49
Eastward CIB+ 20.3
Eldest Souls New 45.5
Elliot Quest New 28.48
Enclave HD New 52.67
Ender Lilies: Quietus of the Knights New 55.00
Endling - Extinction is Forever New 25.76
Epic Chef New 15.57
Espgaluda II New 60.27
Fairy Fencer F: Advent Dark Force New 48.41
FAR: Lone Sails New 49.69
Fast RMX New 71.73
Fatal Twelve New 44.49
Fault Milestone One New 28.49
Fight'N Rage New 45.49
FINAL FANTASY VII & VIII REMASTERED TWIN PACK CIB+ 37.63
Final Fantasy XII: The Zodiac Age New 31.61
Fire Emblem Warriors: Three Hopes New 20.17
Flinthook New 45.49
Flipping Death CIB+ 28.39
Foretales New 19.29
Forgotton Anne CIB+ 35.49
Fran Bow New 111.48
Freedom Finger CIB+ 77.4
Freedom Planet New 57.39
Furi CIB+ 48.64
Gal Metal: World Tour Edition CIB+ 17.69
Gato Roboto [Special Reserve Edition] New 40.00
Ghost 1.0 + Unepic Collection: Standard Edition New 30.00
Ghost of a Tale New 66.61
Going Under New 37.47
Golf Story New 82.75
Gotta Protectors: Cart of Darkness New 45.35
Grandia HD Collection New 82.51
GrimGrimoire OnceMore [Deluxe Edition] New 42.33
GRIS [Limited Special Reserve] CIB+ 60.00
Gunbrick: Reloaded New 24.68
Gunlord X New 90.00
Guns, Gore & Cannoli 1 & 2 New 140.00
Gunvolt Chronicles: Luminous Avenger iX New 84.5
Gyakuten Saiban 123: Naruhodo Selection New 41.49
Hades New 39.19
Haven New 45.49
Heaven's Vault New 32.15
Hero Must Die. Again New 56.5
Heroland Knowble Edition New 18.63
Hollow Knight CIB+ 31.5
Horgihugh and Friends New 28.18
Hot Wheels Unleashed New 22.03
Hotline Miami Collection [Special Reserve] New 40.00
Ib New 55.46
Ikenfell New 42.56
Immortals Fenyx Rising New 15.22
In Sound Mind: Deluxe Edition New 21.81
Indivisible New 19.41
Infernax New 50.5
Inscryption [Special Reserve] New 200.00
Ion Fury New 35.35
ITTA CIB+ 35.00
ITTA [Steelbook Edition] New 50.00
Ittle Dew 2+ New 43.45
Jamestown+ New 50.98
Joe Dever's Lone Wolf New 65.54
Katamari Damacy REROLL New 23.45
Katanakami New 42.3
Kaze and the Wild Masks New 32.44
KeyWe New 25.49
Killer Queen Black New 16.13
King's Bounty II New 17.85
Kingdom Hearts: Melody of Memory New 20.59
Kingdoms of Amalur: Re-Reckoning CIB+ 19.98
Knights and Bikes New 45.49
Kotodama: The 7 Mysteries of Fujisawa New 19.45
KUNAI New 30.00
L.A. Noire CIB+ 29.99
Lair of the Clockwork God New 39.13
Layers of Fear: Legacy New 147.86
LEGO Star Wars: The Skywalker Saga New 20.48
Little Nightmares II CIB+ 20.75
Lonely Mountains: Downhill SRG#46 New 86.79
Loop Hero CIB+ 25.00
Loop Hero [Collectors Edition] New 40.00
Love Esquire [Limited Edition] New 90.5
LoveKami Trilogy New 35.00
Lumines Remastered New 32.5
LUNARK New 49.52
Mario + Rabbids Sparks of Hope CIB+ 15.42
Mario + Rabbids: Kingdom Battle CIB+ 12.5
Mario Party: Superstars CIB+ 39.5
Marvel Ultimate Alliance 3: The Black Order CIB 30.00
Mary Skelter 2 New 40.00
Mary Skelter: Finale New 49.39
Mato Anomalies New 19.73
Mega Man 11 New 20.48
Mega Man Zero/ZX Legacy Collection CIB+ 24.5
Megadimension Neptunia VII New 45.5
Mighty Gunvolt Burst New 44.45
Mighty Switch Force! Collection CIB+ 45.49
Ministry of Broadcast New 26.72
Minoria New 50.47
Miracle Snack Shop [Limited Edition] New 35.00
Moero Chronicle Hyper New 90.35
Moero Crystal H New 50.77
Momodora: Reverie Under the Moonlight New 71.68
MONARK Deluxe Edition New 37
Monster Hunter Generations Ultimate New 42.69
Monster Hunter Stories 2: Wings of Ruin New 31.49
Monster Sanctuary New 58.46
Monstrum New 38.5
Mother Russia Bleeds [Special Reserve] New 45.00
Mother Russia Bleeds [Special Reserve] New 45.00
Ms. Splosion Man CIB+ 31.98
Mulaka New 60.00
Murder By Numbers Collectors Edition New 80.36
Mushihimesama New 60.7
My Friend Pedro [Special Reserve Edition] New 45.00
Narita Boy New 45.55
NEO: The World Ends With You CIB+ 20.5
NeoGeo Pocket Color Selection Vol. 1 New 43.06
Neon Abyss New 42.38
Neversong & Pinstripe CIB+ 37.5
New Super Lucky's Tale New 33.59
New Super Mario Bros. U Deluxe New 39.5
Ni no Kuni: Wrath of the White Witch New 26.5
NieR: Automata - The End of YoRHa Edition New 39.5
Night in the Woods New 59.92
Night Trap: 25th Anniversary Edition New 56.06
Ninja Gaiden: Master Collection New 50.42
No Man's Sky CIB+ 26.25
No More Heroes CIB+ 40.5
No More Heroes 2: Desperate Struggle CIB+ 35.92
No More Heroes III CIB+ 15.5
Ocean's Heart New 53.33
Octahedron New 45.43
Octopath Traveler New 52.43
Octopath Traveler II New 39.99
Oddworld - Collection New 36.25
à Œkami HD New 32.99
One Step From Eden New 34.15
Oniken + Odallus Collection New 36.51
Opus Collection CIB+ 22.49
Ori: The Collection New 28.97
Othercide New 32.45
Outlast: Bundle of Terror / Outlast 2 CIB+ 250.00
Overlord: Escape from Nazarick New 35.97
Owlboy CIB+ 16.48
Oxenfree New 99.53
Panzer Dragoon New 40.5
Panzer Paladin New 48.13
Pathway New 27.6
Phoenotopia: Awakening [Premium Edition] New 114.25
Pikmin 3 Deluxe CIB+ 35.00
Pikmin 4 New 42.79
Piofiore: Fated Memories New 27.95
PixelJunk Eden 2 New 25.49
Pocky & Rocky Reshrined New 25.49
Pokémon Legends: Arceus New 41.19
Pokémon Mystery Dungeon: Rescue Team DX CIB+ 40.5
Pokémon Sword CIB+ 30.26
Pokémon Violet New 44.5
Postal Redux New 25.5
PowerSlave: Exhumed New 55.00
Prinny Presents NIS Classics Volume 2 [Deluxe Edition] New 43.99
Prodeus New 40.67
Project Warlock New 67.14
Puyo Puyo Tetris New 17.5
Q.U.B.E. 2 New 51.32
Quake New 38.49
Radiant Silvergun New 58.09
Rainbow Billy: The Curse of the Leviathan New 23.82
Razion EX New 90.00
realMyst: Masterpiece Edition New 78.08
République: Anniversary Edition New 35.49
Return of the Obra Dinn New 58.18
Return to Monkey Island CIB+ 43.09
Return to Shironagasu Island CIB+ 28.5
Risk of Rain 2 New 14.7
River City Girls CIB+ 80.23
River City Girls 2 New 50.5
River City Girls [PAX Variant] New 142.6
River City Girls Zero New 44.49
River City: Rival Showdown New 30.49
Rogue Heroes: Ruins of Tasos CIB+ 30.00
Roki CIB+ 30.00
Rolling Sky Collection CIB+ 20.00
Root Film New 34.09
RUINER [SWITCH RESERVE] New 45.00
Rune Factory 3 Special New 23.41
Rune Factory 3 Special New 23.41
Rune Factory 4 Special [Archival Edition] New 90.00
Sakuna: Of Rice and Ruin New 27.5
Sally Face [Deluxe Edition] New 224.81
Sam & Max Save the World New 43.5
Sam & Max: Beyond Time and Space Remastered New 44
Samurai Jack: Battle Through Time New 70.48
Save me Mr Tako: Definitive Edition New 33.5
Scott Pilgrim vs. The World: The Game - Complete Edition New 32.49
Sea Horizon [Limited Edition] New 42.49
Sea of Solitude: The Director's Cut New 20.00
Seabed New 40.42
SeaBed [Limited Edition] New 135.38
Senran Kagura Reflexions New 129.74
Senren * Banka New 70.00
SENSEs: Midnight [Limited Edition] New 47.43
Serious Sam Collection [Switch Reserve] New 50.00
Seven Pirates H New 30.00
Seven Pirates H New 30.00
Seven Pirates H New 30.00
Shadow Man Remastered New 48.39
Shadowgate New 62.5
Shadowrun Trilogy New 45.00
Shadows of Adam New 34.49
Shadowverse: Champion's Battle New 21.95
Shantae New 39.34
Shantae and the Pirate's Curse New 381.21
Shantae and the Pirate's Curse Box 49.62
Shantae and the Seven Sirens New 50.2
Shantae: Half-Genie Hero [Ultimate Edition] New 38.2
Shantae: Risky's Revenge New 38.51
Shaq Fu: A Legend Reborn New 19.57
Shikhondo: Soul Eater New 34.44
Shin Megami Tensei III: Nocturne HD Remaster New 25.5
Shin Megami Tensei V New 22.38
Shin Megami Tensei V New 22.38
Shining Resonance Refrain [Draconic Launch Edition] New 48.6
Sine Mora EX New 23.02
Skelattack New 45.00
Slime-san New 43.74
Smile For Me New 30.00
SNK Heroines Tag Team Frenzy New 29.15
Sol Cresta: Dramatic Edition New 45.48
Sonic Colors Ultimate CIB+ 15.48
Sonic Frontiers CIB+ 21.62
Sonic Mania New 16.51
Spiritfarer New 28.95
Splatoon 2 CIB+ 19.67
Splatoon 3 New 43.99
Star Wars Pinball New 19.72
Star Wars: Knights of the Old Republic New 60.49
Star Wars: Knights of the Old Republic II - The Sith Lords New 59.79
Star Wars: Knights of the Old Republic II - The Sith Lords New 59.79
Star Wars: Republic Commando New 26.45
Steel Assault New 48
Streets of Rage 4 New 33.45
Strife: Veteran Edition New 30.00
Subnautica + Subnautica: Below Zero New 32.49
Super Blood Hockey New 60.96
Super Bomberman R New 20.42
Super Mario 3D All-Stars CIB+ 70.00
Super Mario Maker 2 CIB+ 30.48
Super Meat Boy New 38.5
Super Meat Boy Forever New 25.98
Super Monkey Ball Banana Mania New 13.48
Supraland New 33.75
Sushi Striker: The Way of Sushido New 12.17
Taiko no Tatsujin Rhythm Festival New 15.5
Tails of Iron [Crimson Knight Edition] New 42.89
Tales of Vesperia: Definitive Edition New 30.41
Tandem: A Tale of Shadows New 20.48
Terraria New 24.66
DioField Chronicle CIB+ 25.46
Elder Scrolls V: Skyrim CIB+ 35.31
Falconeer: Warrior Edition New 18.88
Friends Of Ringo Ishikawa New 26.73
Great Ace Attorney Chronicles CIB+ 30.98
Knight Witch Deluxe Edition New 32.07
Legend of Heroes: Trails of Cold Steel III - Extracurricular Edition CIB+ 31.77
Legend of Tianding New 45.00
Legend of Zelda: Tears of the Kingdom New 47.46
Letter: A Horror Visual Novel [Limited Edition] New 73.75
The Messenger [Special Reserve Games Edition] New 280.00
Missing CIB+ 35.5
Mummy Demastered New 57.71
Red Lantern New 58.5
RED STRINGS CLUB [SWITCH RESERVE] New 38.5
Silver Case 2425 Deluxe Edition CIB 25.00
TakeOver New 47.41
Talos Principle New 40.00
Touryst New 60.00
Wonderful 101: Remastered New 23.5
World Ends with You: Final Remix New 53.95
There Is No Game: Wrong Dimension New 53.51
Thumper New 45.45
Time on Frog Island CIB+ 17.43
Timespinner [Limited Run] CIB+ 77.28
Tiny Barbarian DX New 33.97
To The Moon New 67.98
ToeJam & Earl: Back in the Groove! CIB+ 49.86
Tokyo Mirage Sessions #FE Encore New 66.72
Tokyo Mirage Sessions #FE Encore New 66.72
TowerFall New 45.5
Travis Strikes Again: No More Heroes CIB+ 24.99
Treasures Of The Aegean New 17.98
Trigger Witch New 34.59
Trigger Witch - Limited Edition New 57.66
Trover Saves the Universe New 37.76
Turok / Turok 2: Seeds of Evil New 167.4
Twin Blades of the Three Kingdoms New 30.00
Two Point Hospital New 26.5
UnderMine New 51.08
Unravel Two CIB+ 18.35
Unreal Life New 39.15
Unsighted New 47.2
Untitled Goose Game New 22.45
Valfaris New 39.64
Valis: The Fantasm Soldier Collection New 70.61
Valis: The Fantasm Soldier Collection II New 50.5
Valkyria Chronicles 4 New 66.81
Very Very Valet New 17.77
Wandersong CIB+ 33.99
Warborn New 16.6
Warhammer 40,000: Mechanicus CIB+ 21
WarioWare: Get it Together! CIB+ 24.55
West of Dead New 39.1
Wizard of Legend New 55.00
Wonder Boy: The Dragon's Trap New 39.14
World Of Simulators New 45
Wreckfest New 25.5
Wulverblade New 68.83
Xenoblade Chronicles 2 Loose 42.6
Xenoblade Chronicles 2: Torna the Golden Country loose 45
Xtreme Sports New 50.5
Yoku's Island Express CIB+ 35.5
Yooka-Laylee and the Impossible Lair New 35.5
Young Souls New 34.49
Yu-Gi-Oh! Legacy of the Duelist: Link Evolution CIB+ 17.69
Yuppie Psycho: Executive Edition (Elite Edition) New 45.49
Yurukill: The Calumniation Games (Deluxe Edition) New 20.73
Zombies Ate My Neighbors and Ghoul Patrol New 40.09
PS2
Armored Core Nexus CIB105.33
PS4
88 Antarctica New 45.00
Antartica 88 [Variant Cover] New 185.5
Deadpool CIB+ 76.33
Death Park New 45
Death Park New 45
Death Park New 45
Death Park New 45
Digimon Survive New 16.55
Divinity: Original Sin II - Definitive Edition New 71
Doki Doki Literature Club Plus! New 21.17
Helldivers [Super-Earth Ultimate Edition] CIB+ 45.00
Minecraft: Story Mode - A Telltale Games Series - The Complete Adventure CIB+ 58.41
Outriders: Worldslayer New 18.48
Revenge of The Bird King New 31.99
Saints Row: The Third Remastered New 15.1
Senran Kagura Burst Re:Newal [At the Seams Edition] New 60.49
Senran Kagura Burst Re:Newal [Tailor Made Edition] New 47.99
Senran Kagura: Peach Beach Splash (No Shirt, No Shoes, All Service Edition) New 71.5
Shadow Warrior 2 [Special Reserve Edition] New 235.52
Super Perils of Baking Special Edition [SEGA Outerbox] New 120.00
Swords of Ditto: Mormo's Curse [Special Reserve Edition] New 40.00
Tamashii New 450.00
Teenage Mutant Ninja Turtles: Mutants in Manhattan CIB+ 40.00
Valkyria Chronicles Remastered Steelbook Edition New 30.45
VITA
2064: Read Only Memories New 67.97
88 Heroes New 40.6
99Vidas New 125.97
Hole New World New 48.82
Rose in the Twilight New 192
Winter's Daydream [Limited Edition] New 64.1
Aegis of Earth: Protonovus Assault New 26.49
Akiba's Beat New 30.25
Akiba's Trip: Undead & Undressed CIB+ 25.49
Alone With You New 38.5
Angry Birds Star Wars New 20.48
Another World: 20th Anniversary Edition New 40.49
Antiquia Lost New 34.75
Aqua Kitty: Milk Mine Defender DX New 51.5
Army Corps of Hell New 23.99
Asdivine Hearts New 35.46
Astro Aqua Kitty [Limited Edition] New 64.7
Atari Flashback Classics New 60.61
Atelier Escha & Logy Plus: Alchemists of the Dusk Sky (Limited Edition) New 168.49
Awesome Pea Collection [Limited Edition] CIB+ 40.1
Axiom Verge Multiverse Edition New 56.56
Back in 1995 [Limited Edition] New 191.4
Bard's Gold New 33
Bastion New 64.16
Batman: Arkham Origins Blackgate CIB+ 23.67
Bit.Trip Presents...Runner2: Future Legend of Rhythm Alien New 33.49
Bit.Trip Presents...Runner2: Future Legend of Rhythm Alien New 33.49
Bloodstained: Curse of the Moon New 118.23
Borderlands 2 CIB+ 23.49
Breach & Clear New 308.01
Broken Age New 33.77
Bunny Must Die: Chelsea and the 7 Devils New 95
Call of Duty: Black Ops Declassified CIB+ 22.29
Call of Duty: Black Ops Declassified Loose 18.98
Chaos;Child New 45.61
Chasm CIB+ 60.49
Child of Light CIB+ 24.56
Claire: Extended Cut CIB+ 35.17
Code:Realize - Future Blessings Loose 14.9
Code:Realize - Guardian of Rebirth New 25.5
Code:Realize - Guardian of Rebirth Loose 14.2
Conga Master Go! [Limited Edition] New 51.83
Corpse Party: Blood Drive New 58.77
Cosmic Star Heroine CIB+ 43.25
Criminal Girls 2: Party Favors CIB+ 74.09
Criminal Girls: Invite Only CIB+ 54.49
Croixleur Sigma New 40.49
Cursed Castilla EX [Limited Edition] New 60.5
Curses 'N Chaos New 38.72
Damascus Gear: Operation Osaka New 40.51
Damascus Gear: Operation Tokyo New 41
Danganronpa 2: Goodbye Despair Loose 19.41
Danganronpa 2: Goodbye Despair Loose 19.41
Danganronpa Another Episode: Ultra Despair Girls New 31.5
Danganronpa V3: Killing Harmony CIB+ 58.89
Danganronpa: Trigger Happy Havoc CIB+ 25.97
Dariusburst: Chronicle Saviours New 47.38
Deadbolt New 42.44
Death Mark CIB+ 23.22
Death Tales [Limited Edition] New 40.4
Deemo: The Last Recital New 34.22
Defender's Quest: Valley of the Forgotten New 37.86
Demon Gaze Loose 22.22
Demon Gaze CIB+ 25.81
Demon Gaze II New 74.66
Demon's Tier+ [Limited Edition] CIB+ 55.49
Dengeki Bunko: Fighting Climax CIB+ 25.5
Devious Dungeon - Limited Edition CIB+ 67.38
Devious Dungeon 2 [Limited Edition] New 84.5
Digimon Story: Cyber Sleuth CIB+ 65.9
Disgaea 4: A Promise Revisited CIB+ 25.49
Dokuro New 52.94
Dragon Fantasy: The Black Tome of Ice New 34.5
Dragon Fantasy: The Volumes of Westeria New 40.49
Dragon Sinker: Descendants of Legend New 35.5
Dungeon Travelers 2: The Royal Library & The Monster Seal CIB+ 53
Dynasty Warriors: Next Loose 16.66
Earth Defense Force 2: Invaders from Planet Space New 28.19
EMMA: Lost in Memories [Limited Edition] New 52.49
Exile's End New 39.65
Exist Archive: The Other Side of The Sky Loose 18.48
Fate/Extella: The Umbral Star Noble Phantasm Edition New 46.26
Fernz Gate New 30.69
Final Fantasy X / X-2 HD Remaster Loose 25.49
Final Fantasy X-2 HD Remaster New 61.19
Forma.8 New 32.5
Freedom Wars CIB+ 13.48
Furwind [Limited Edition] CIB+ 40.5
Futuridium EP Deluxe New 45.97
Gal*Gun: Double Peace CIB+ 32.34
Ghoulboy [Limited Edition] New 160.5
God of War Collection New 74.75
Grand Kingdom New 47.6
Gravity Rush CIB+ 44.5
Guard Duty [Limited Edition] CIB+ 47.38
Gundemoniums New 84.18
Gunhouse New 30.38
Habroxia New 129.94
Habroxia 2 [Limited Edition] New 65.5
Halloween Forever [Limited Edition] New 74.5
Home: A Unique Horror Adventure New 35.92
Horizon Chase Turbo [Limited Edition] New 76.81
Hot Shots Golf: World Invitational New 26.19
HtoL#NiQ The Firefly Diary: Limited Edition New 59.25
Hue New 40.5
Hyperdevotion Noire: Goddess Black Heart CIB+ 35.5
Hyperdimension Neptunia PP: Producing Perfection CIB+ 35.97
Hyperdimension Neptunia Re;Birth1 CIB+ 47.01
Hyperdimension Neptunia Re;Birth1 CIB+ 47.01
Hyperdimension Neptunia Re;Birth2: Sisters Generation CIB+ 60.49
Hyperdimension Neptunia Re;Birth2: Sisters Generation CIB+ 60.49
Hyperdimension Neptunia Re;Birth3: V Generation CIB+ 55.95
Hyperdimension Neptunia Re;Birth3: V Generation CIB+ 55.95
Hyperdimension Neptunia U: Action Unleashed CIB+ 43.81
Iconoclasts New 96.5
Indigo 7 : Quest for Love New ?
Jak and Daxter Collection CIB+ 50.49
Jet Set Knights [Limited Edition] New 100.5
Jet Set Knights [Limited Edition] New 100.5
Just Ignore them + My Big Sister Collection New 60.49
Kawaii Deathu Desu New 45.5
Killzone: Mercenary Loose 24.49
Killzone: Mercenary CIB+ 32.68
Knightin' + [Limited Edition] New 60.45
Knytt Underground New 128.14
La-Mulana Ex New 38.03
LEGO Batman 2: DC Super Heroes Loose 11.33
LEGO Jurassic World CIB+ 13.44
LEGO Ninjago: Shadow of Ronin Loose 17.12
LEGO Star Wars: The Force Awakens New 28.75
LEGO Star Wars: The Force Awakens Loose 12.21
LEGO The Lord of the Rings Loose 10.49
Lone Survivor: The Director's Cut New 42.49
Luckslinger [Limited Edition] New 60.41
Lumines: Electronic Symphony New 18.61
Mary Skelter: Nightmares CIB+ 92.87
MegaTagmension Blanc + Neptune VS Zombies New 37.58
MeiQ: Labyrinth of Death CIB+ 25.39
Mercenary Kings: Reloaded Edition [Limited Edition] New 106.71
Metagal [Limited Edition] CIB+ 100.35
Metal Gear Solid HD Collection CIB+ 46.49
Metal Slug 3 New 115.48
Mind Zero CIB+ 20.48
Mooseman [Limited Edition] New 119.05
Mortal Kombat CIB+ 26.99
MotoGP 13 CIB+ 23.83
MUSYNX New 50.49
Muv-Luv New 53.36
Muv-Luv Alternative New 66.95
Muv-Luv Complete Set New 90.5
My Aunt is a Witch [Limited Edition] New 55.5
Mystery Chronicle: One Way Heroics New 27.94
Need for Speed: Most Wanted - A Criterion Game CIB+ 20.32
Neurovoider New 35.5
Nicole [Limited Edition] New 48.22
Night Trap: 25th Anniversary Edition New 58.99
Nova-111 New 28.67
Nurse Love Addiction New 59.18
Nurse Love Syndrome New 50.49
Nurse Love Syndrome Loose 15.49
Oceanhorn: Monster of Uncharted Seas New 52
Octodad: Dadliest Catch New 46.36
Oddworld: Abe's Oddysee - New 'n' Tasty New 149.5
Oddworld: Munch's Oddysee HD New 52.5
Oddworld: Stranger's Wrath HD New 69.73
Odin Sphere Leifthrasir CIB+ 72.45
Odin Sphere Leifthrasir Loose 70.5
One More Dungeon CIB+ 60
Operation Abyss: New Tokyo Legacy CIB+ 31.5
Oreshika: Tainted Bloodlines New 93
Papers, Please New 115.47
Pato Box [Limited Edition] New 73.23
Penny-Punching Princess New 45.41
Period: Cube - Shackles of Amadeus New 54.65
Persona 4 Golden Loose 25.37
Persona 4 Golden New 61.12
Persona 4: Dancing All Night - Disco Fever Edition New 145.5
Phantom Breaker: Battle Grounds New 53.5
Pix the Cat New 28.84
Plague Road New 43.4
PlayStation All-Stars Battle Royale New 31.74
Proteus New 36.49
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2024.05.28 03:03 Spike_Flings Chapter 2: The Second Son Saga [Fantasy, - 5485 words]

This idea came to me in college and I've sort of played around with it over the years. I would appreciate any constructive criticism, especially focused on the prose and characters. This would be the introductory chapter of one of the main characters, Karl Klug, who is an important noble in his country. I hope you enjoy!



KARL 1
Three men stood beneath a great oak branch, hands bound and nooses pulled tight around their necks. The branches connected to a mighty tree, old as the mountains themselves. The men were all silent, as were the other corpses gently swinging in the morning breeze. The air was still cold from the dew, not yet banished by the still rising sun.
“If you have anything left to say, now would be the time.” Karl Klug, Lord of the Wald said as he eyed them with disgust from the back of his chestnut horse destrier. He sat tall in the saddle, his close cropped brown hair and clean shaven face a far cry from the ragged appearance of the condemned. His heavy, black, woolen cloak was pulled tight, the hood up to block out the wind. Under the cloak he wore a simple brown doublet, with a crest bearing the black tree on a green field that was the sigil of his house. Karl always made sure to represent House Klug when acting as Lord, as was his duty.
These men were thieves, rapists, and murderers. They attacked travelers on the roads of the Wald, and it was Karl’s duty, as Duke of the Wald and Lawspeaker to the King, to keep those roads safe. The law demanded only one punishment for their transgressions. Their fate would serve as a warning to other would-be bandits.
The first man, a stern face and hard eyes, said nothing, but spat on the ground. The second man, fat and whimpering, managed to speak out in between choked sobs “Please m’lord. Mercy! They made me do it!”
The last man, a boy no older than fifteen, barked at him to be quiet. “We’re done for Ozzy. Go to the Wainman with some dignity, would you?” Such bravery in one so young. What could he have become if he followed a different path?
With that, Karl nodded to Jorivs, his household Resolver, who pulled hard on the ropes, them each one by one into the air, sending them kicking and choking into the Beyond. The second one, Ozzy, screamed and begged for his mother before the rope cut him off. Jorivs tied the final line off to a stake, while Wolter, his barber-surgeon companion, scribbled something down in a book. “They go to their doom in all different spirits, yet they all dance the hangman’s jig just the same.” He said as he turned a page.
“Amazing the lessons they teach at Spierpont.” Jorvis chuckled as the last pair of legs stopped kicking. “Shame Lemba couldn’t join us.”
“The Elf has seen his fair share of death. Let him enjoy his peace.”
“I only jest, my lord.” Jorvis said as he took a sip from his canteen. He motioned for Wolter to take a drink, but the older man was too busy furiously scribbling in his notebook to notice.
Karl looked to the east. The dawn was still cresting the horizon. “I’m off to the woods. I will not be disturbed.” Matilda and the children will still be sleeping. Best not to wake them with my return.
His pages nodded and replied in unison “Yes my lord.” By Karl’s standing order, Jorvis was peeling the boots of the dead men, better they should shoe a pauper than rot on the condemned. Wolter sketched the hanging men in his book, taking special care to note the lolling tongues and soiled breeches. Jorvis had the boots in a loose pile when he pulled a knife and a small pouch from his belt. “The eyes,my lord?”
He nodded grimly. “Hain will have his due.” Jorvis took a small stool and set to work, all six organs removed in a few quick flashes of the blade. Jorvis placed the grim package in its usual place on Baldur, Karl’s horse. With the bloody sack tied to his saddle, Karl rode off towards the thick forest nearby, a page in tow to hold his horse.
The page started to speak, and then stopped himself. He was a small boy, ten or eleven at the most. He had been to several executions before and not once had he been troubled by the sight of death.
Karl noticed the indecisive boy and helped him along.
“Something bothering you, Wiglaf?”
“The” came a squeak. Wiglaf cleared his throat and tried again. “The Resolver grumbles, lord. He grumbles that it would be easier to take the eyes before hanging the condemned.” He said meekly
“I know he grumbles. I know. But this is the way things are to be done. Taking their eyes before they hang is not the punishment for their crime. These men had their trial, and I sentenced them to die, not to be tortured. Do you understand, Wiglaf?”
“Aye, my lord. I understand.” Wiglaf nodded.
Wiglaf. So eager to learn but so nervous to offend. I’ll talk to his father the next time we meet.
This was the first time in months he had a chance to take in the forest. The influx in banditry in the past year had been a great source of woe not only to Karl, but to the Waldish people as a whole. They had enough to be fearful of without their fellow man adding to their problems. It had kept Karl up many nights, as he racked his brain trying to figure out the cause.
He had built roads, sick houses, held fairs, endorsed the Bard’s college, done all in his power to keep the people happy and content and quiet, and yet, there were some who still turned to crime. Why? No. Not now. Not here. Karl decided that he needed to rest his mind from constant affairs of state, and allow himself to relax before he made his offering.
They reached a clearing, and Karl dismounted. “Hitch up Baldur and rub him down. Have something to eat from my pack if you get hungry. I don’t know how long I’ll be gone this time.” The page nodded. Wiglaf, a good lad, if a bit timid at times. Weather had concealed his typical path into the great forest, but muscle memory lead his way.
He enjoyed his solitary walks in the woods, it gave him a chance to forget the woes of rulership, the frustrations of fatherhood, and the horrible curse that befell his bloodline. Now that things had quieted down with the bandits, Karl hoped he might have more time to be a husband to his wife, Matilda, and a father to their children. His three children, though nearly adults themselves, still tended to make a commotion. What they need is a firm hand. Their mother will spoil them rotten if she has her way. Karl laughed to himself. She always gets her way.
His feet knew where he was going, even if his mind did not. He always returned to the same place, no matter what direction he turned. Are the woods themselves magic, or just the creatures that inhabit it? He wondered as he found the well worn dirt path covered by a tunnel of tree limbs. The branches must have kept this clear from storms after all.
Few who entered the Wald came back alive, save for the Elves and their slaves, who usually came out in one piece. Most who walked too far past the tree line simply vanished. There were rumors, of course. Even his own grandfather had claimed that he was, in fact, the same Helm Klug that had vanished without a trace in the winter of 542. He had fallen through a tree hollow and into the myth shrouded realm of Cunnan, where time flows differently, or so the stories go. As such, though ninety-five years had passed from the time of the vanishing, Helm had only aged ten years or so.
Karl’s realm was a dangerous one, even without the recent rise of the highwaymen. To an outsider, walking alone in the duchy of the Wald was like strolling past a dark alley with coins jingling loudly. To Karl Klug, Lord of the Wald, it was like walking into his own bedroom. He had grown up here, he knew that danger lurked behind every tree, above every branch, and below every root. Not once had he seen anything like what Grandfather Helm had rambled about. No fairies or witches or traces of Hain. Still, one had to tread carefully here. Even Karl would not dare to venture in some parts of the forest, for an ancient force still had power in the dark parts of Bordrim.
I hope Hain will be pleased with my tribute. To survive here, one had to know when to fight, when to run, and when to submit. Some might call that heretical, going against the word of the church, But that was not something he wished to think about now, not when he was trying to be at peace.
The fresh air cleared his head and refreshed his spirit. Karl took a long, deep breath filling his lungs with the cold morning damp. He knew he would not be distrubed here, as none but the Duke of the Wald may travel to this part of the woodland.
He had been Duke ever since the death of his father when he was just four years old, though he had not ruled in his own right until he was fourteen. In that time, he had learned much from his regents, and his mother, who was far more capable than many made her out to be. She had taught him that most men, however pure their intentions may seem, nearly always had some ulterior motive that they wished to advance. Karl remembered that as his most valuable lesson, and it had assisted him greatly as he came of age. My father’s sycophants did not last long when I ruled in my own right.
The sound of rushing water came to his ear as he walked by the River Cember where his father had drowned. He used to intentionally go out of his way to avoid being near it, but now he barely gave it a second glance. I used to be so afraid of the water, until I understood why Father died. But by then, Mother had the Court Elf Lembe throw me in Sillac Pond. How I thrashed! It didn’t seem so scary after that. Fate is far more terrifying than any danger and far more comforting than any joy. Once you have been through the worst, everything else can be done with ease.
Karl heard a branch snap in the trees to his right, and his hand slipped to the silver coated dagger at his hip. He stood still as the trees around him, slowly moving his eyes from right to left as he looked for the source of the noise. Funny. I was afraid of harmless water for so many years when there were very real threats all around me the entire time. As long as I stay on the path, no beast would dare harm me.
There were no further noises, and judging by the humming of insects and the singing of birds, there was no real threat. Probably a stag or maybe one of Grandfather Helm’s Fae creature having a laugh at my expense. He continued walking for some time, climbing up small, rolling hills and ducking under fallen tree trunks, before reaching a final, gentle incline which led to Hidden Hill. That was where they found his older brother, Jasper, hanging from the tree at the top. That was the day his father had told him about the curse that stalked their family.
He made his way up the slope, as he had countless times before. The top of the hill was clear, save for one tree, planted by Karl’s grandfather Helm upon regaining control of the Wald after decades of Gaunt rule. His family adopted that tree, and made it part of their heraldry. A great black tree, sounded by the green of the forest.
The air seemed to resist being pulled into his lungs now. He had to unclench his teeth, relax his shoulders. He looked down at his fingers. He had scraped away the flesh near the nails on his thumbs and middle digits. How long have I been at it this time? It is difficult to relax when I am surrounded by some many painful reminders of the past. No matter how deep in this forest I walk, I cannot escape the memories that tears at me.
He kept his eyes low. Karl enjoyed seeing the blooming flowers and vibrant weeds that grew along the path he always walked. One particular group of plants caught his eye. A clover patch. The old folks said that in every clover patch, there was one particularly special sprout. And so Karl made a point to look over each and every patch he saw, even if only a passing glance.
What’s this? He said to the tiny green sprout as he crouched down for a closer look. A clover with four leaves. Lucky, lucky. Karl smiled as he plucked the clover and put it in his coin purse. And a good omen too. I know Otto will love this.
Karl continued up the path, and sat beneath the great black tree, looking out onto the castle that stood proud below in the clearing. Grey Hallow, it was called, and it was among the oldest in Bordrim, predating even the great fortresses of the Empire that many great houses now called their own. With two rings of thick, tall walls and towers covering every angle of approach, no enemy had ever successfully stormed the walls. Though a knife in the back is sometimes better than a ram at the gate, as history has proved.
Karl grabbed the now wet sack that Jorvis had provided. He quickly found a small knothole and stuffed the grisly offering side. The Dule clasped his hands together and bowed his head. “Haim, please take this offering that we may know quiet peace.” He sighed. Was Haim even real? Or just another story to make obedient children?
As Karl reclined in the unearthed roots of the black oak, he smiled. *Real or not, offerings to Haim aren’t all terrible.*This was the tree that he had married Matilda under, after he came back from the Siege of Hammerring, the last remaining Imperial stronghold in Bordrim. He had made a fortune by securing the ransoms of important Imperials, bringing House Klug from the embarrassment of near bankruptcy to extreme wealth in a single day. He had spent coins like a drunken gambler blessed with immovable luck that night, and from then on men had begun to say he was the richest man in the kingdom. I don’t know about any of that. But riches aren’t just measured in gold. Karl thought as he ran his fingers along the black bark of the tree.
Searching through the leather pack he took from his saddle, Karl grabbed the cloth that held the dried venison and cheese he had carried along for his breakfast. The castle will just be coming to life now. He thought as the sun began to climb higher in the sky. After he had broken his fast, he pulled a quill, a tightly sealed ink pot, and a piece of parchment from his sack. He began to write.
“Your smile, a joy
Your laugh, a pleasure.
When we are together,
Troubles are light as a feather.”
Karl would have a servant hide that among Matilda’s things, where she would discover it later. Even after fifteen years of marriage, Karl loved to create these little surprises for his wife, just as she loved finding his cumbersome gifts and clumsy poetry.
A long, steady drumming sounded over the tops of the trees, booming from the direction of Grey Hallow, but far beyond. In the west, birds squaked and scattered to the wind. By the cadence of their beat, Karl knew it was the Elves, come to pay their respects and receive letters of safe passage as required by the Pact. A little earlier than expected. No matter. I prefer early to late. No doubt my Chamberlain, Aldred, will have everything prepared. Karl sprang to his feet, dusted off his trousers, and rolled the dried parchment. He followed the path back to the castle at a quick pace, humming a song his Bard had sung the previous night while they slept under the stars.
The day had well and truly begun upon his return. Servants wearing the green and black of his house dashed about as their duties required. Men stood guard wearing the Great Black Tree of the Klugs on their livery. The halls were alive with chatter and the scuffing of feet. Karl knew a long line of petitioners awaited him in his hall, but everyone knew that an audience with elves took precedence over the squabbles of men. They had all heard the drums, and they would be pressed together like bees in a hive just for a glimpse of the pointy eared outlanders. Every year, young elves Elves embarked on a great journey that they called *THING* or “The Taste” in the Imperial tongue. They spent anywhere from one to one hundred years living among the mortals, learning their ways and customs. Some spent the rest of their millennia-long lives among the mortals, watching dynasties rise and fall, technological marvels stun the world, and should they be unfortunate enough to make friends or find lovers, they witness death on a scale previously unimaginable.
Lemba is due to return home by the end of the year. After seventy years of service to my family, he’s earned his rest. Perhaps one of the newcomers would like a position at court. I would very much like to continue my lessons. Karl flexed his fingers at the mere thought of magic. Outlawed in most realms of men, Karl had insisted on instruction. The training was hard and the consequences if discovered by the Church would be dire, but in a land as dangerous as the Wald, every advantage counted.
The drums boomed, growing louder as the elves approached closer. I must hurry. I cannot insult them by wearing the same clothes I just wore to an execution. Karl jogged down the path from whence he came. Wiglaf was holding Baldur by his reigns, and he snapped to attention the moment he saw Karl approach. “The drums my lo-”
“I heard. Ride ahead and have your father prepare clothing for court.”
“Right away, my lord.” The page said as he galloped away. Karl followed at a quick but more relaxed pace. No sense in appearing sweaty and exasperated for my guests. He reasoned as he rode down the winding path.
His servants were waiting at the gate for him. They grabbed their reins from Baldur, and Karl climbed down from the horse. “Andred has selected your clothing, m’lord. Right this way, if you please.” Onna, the fat seamstress said and she beckoned him to follow. She led him to the laundry, where Karl pulled the dirty articles he had worn for the execution and picked up the courtly clothing she had laid out. He pulled the white linen tunic on first and fasted it was a leather belt inlain with a large silver buckle. His slipped into brown wool trousers next and grabbed a pair of light leather boots. While I won’t appear filthy in front of my guests, high fashion is not something I care to waste my gold on.
Karl sat in his finely carved chair on the dais at the end of the hall. It sat to the right of an identical, but smaller chair where his wife sat*.* She wore a black and green dress with a modestly cut v-neck which exposed her pale skin. Her golden hair lay in one long braid along her shoulder. and her piercing blue eyes smiled back at Karl’s own green. This was the women he had fallen in love with the moment he first spoke to her. She had been less convinced, at first. While he had been the highest born of her many suitors, he had not been her first choice.
“I thought you were boring!” She would tease him later. “You barely said a word the first three times we met.”
“I was nervous.” He would reply. “You captured my heart and my wits that day in High Hibaltia.”
“Well, that wit is what won me. Perhaps I just borrowed it for a time.” She smiled.
Cleverness, justness, kindness. These are the things that make me love you.
The couple held each other's hands as they looked over the court. The chamberlain, Aldred, was quickly giving some last minute instructions to his son and another page, and they immediately scrambled to their work. Guards stood firmly at attention in front of the doors, knowing that they would be facing a hallway full of eager onlookers at any moment.
Their three children stood to the side, talking amongst themselves. Grimbold was the oldest. And doomed to die young, as my brother and uncle have. He was tall, taller than Karl even. He had the arms of a blacksmith’s apprentice and Karl’s own brown curls. He shared his mother’s sky blue eyes and slender nose, as well as her quick temper. He’ll want more responsibility soon. I’ve already denied him a squireship. Perhaps a minor position at court would assuage him.
Next to Grimbold was Charlotte, their only daughter. She too had Karl’s curly brown hair, but she wore it in a long braid, like her mother. She was just like Matilda, in fact. They were both skilled with numbers, and Charlotte’s fascination with bards rivaled Matilda’s own obsession. The two of them often pleaded with Karl to hire this performer or that one, and Duke Karl Klug, Lawspeaker of Bordrim, would not resist his girls, especially Charlotte. She had just turned fourteen, and would be expecting suitors soon. I doubt any of them would be worthy of her. The two of us share a thin patience for stupidity and love makes fools of us all. Especially this false, courtly love the Pawley’s have been peddling these last centuries.
And then there was Otto, the youngest of the three. He stood in between his brother and sister, obviously uncomfortable and being talked over. Nervous and shy, Otto had trouble making friends with children his age. He got along well enough with Wiglaf, but the two never actively sought each other out for play. Probably waiting for the other to make the first move. Karl thought to himself.
“Otto!” Karl yelled. The boy snapped nearly to attention. “Come here, lad. I have a surprise for you.” The boy warily came before his parents.
“Close your eyes and stick out your hands, Otto.” Matilda gently urged.
Otto did as he was told. “Karl dug around in his coin purse and pulled out the clover and a gold coin. He placed the two in Otto’s open palm.
His eyes beamed just before the rest of his face lit up. “Is it real?” He asked as he squealed at his gift.
“Just found it this morning. I figured, with you as my son, I already have all the luck I need.” Otto grinned wide, his missing baby teeth apparent in his otherwise toothy smirk. “Now, with that coin, I want you to find a book that we can read together. Would you like that?” “Yes, father! Yes, yes!” Otto exclaimed, almost shaking with excitement.
“Now get back to your place. The Elves will be here soon.:
“Yes, father!” Otto slipped the clover and coin into his own purse and hurried back to his siblings.
Matilda leaned over and kissed Karl on the forehead. “You’re a good man, Karl Klug.” His mind raced back to dawn, and the creaking of ropes. “I try to be, my love.” He kissed her forehead back. There was a commotion behind the doors to the hallway. It started as a low murmur, and then grew in size, becoming a roar of excitement.
Lemba, Karl’s tutor and resident Elf, took
The Elves had arrived.
Two figures, hooded in dark crimson cloaks, approached the dais. Less than a quarter of what I was told to expect. Behind them were six large, muscular, green skinned orcs bound together at wrist and ankle. Less than a tenth of what I had prepared for. Some Orcs had obviously suffered wounds in the recent past, black blood welling up through tightly wrapped bandages at shoulder, scalp, or thigh. Karl knew from past experience that were these wounds even a slight inconvenience to the Elves, the Orc would be killed with no more pity than lame donkey.
The two cloaked figures marched in a praticed cadence as they moved towards the Duke and Duchess. They all move like that in this room. Is it tradition? Or something more calculated? Lemba, can you enlighten me?
“In due time.” The elf’s voice answered in Karl’s mind. “For now, let us see who has survived the journey.
Karl cast a quick and silent spell to identify the travelers, his only tell was a twitch of the nose, which may have been mistaken for an aborted sneeze.
Viksna and Piske Dun Beske, twin siblings of a prominent Orhani family. Lemba leaned and whispered into Karl’s ear. “The youngest children of a powerful family of sorcerors. T
“Viksna and Piske you illuminate my land with your presence.” Karl’s voice boomed across the hall. It had been so long since he had shouted without magical amplification that he wondered if his throat could even yell anymore.
The two outsiders removed their hoods and stood with clasped hands and bowed heads. Their hair golden, their ears pointed, they were both of a similar height and build, shorter than most men in the room, and Karl could tell they were thin even under their robes.
“And you honor us with your hospitality, Lord Klug.” The pair said in unison.
“You’ve arrived sooner than expected. Was your trip pleasant?”
“We ran into some trouble with monsters, I’m afraid.” Piske said, matter of factly.
“ They devoured quite a few of our slaves.” Viksna added. And of course, the Shadow King must have his due. Our traveling companions were not to his liking. We two and The six Orcs you see behind us are all that is left, I’m afraid, out of the seventeen souls we departed with. Ah, yes. The older races call Haim by his title and dare not refer to him by name. A superstitious bunch, the Elves.
Three slaves for each of us is hardly fitting.” Piske scoffed.
“A shame. I will see that they are tended to. And my servants shall make up for your deficit. See these creatures to their quarters.” He ordered with a wave of his hand.
Guards cautiously herded the six chained beasts on the points of spears, but the broken creatures simply did as they were told and offered no resistance, not even a scowl. They were broken in mind and spirit, they simply existed to do as they were told. Even still, they looked as if they could crush a man’s skull without much effort, and so the guards insisted on caution. I cannot say I blame them.
The instant their slaves were gone from the room, the elves both went down to one knee, each pulling a small bundle from their cloaks. In unison they spoke. “We have come to pay tribute to the Lord of the Wald. Bordermaster, River Watcher, Upholder of the Pact. We offer these small tokens to you, Great Lord.”
Karl pushed up from his seat on the dais and walked towards the pair, gesturing them to stand. This well rehearsed speech never fails to delight my courtiers. “You have left your great capitol of Orhani to live amongst the lesser lived. You have endured freezing cold and driving rain. You have crossed river and mountain, field and fell, and traversed the Wald itself. You have fought beast and monster and seen many things that Man fears in his dreams. You have lost friends and companions along your way, and for that, you have our sympathy. However, all is not lost, and these deaths have not been in vain. You have proved yourselves worthy of fellowship through your very deeds. I bid you stand, as friends of Men.” The two figures stood, pulling back their hoods as the ritual demanded. They both looked as beautiful as painted godlings, young as if in their prime, though each must have seen a hundred years come and go.
The two approached, stepping slowly, deliberately, in unison to the dais where Karl sat. Piske stepped forward, leaving his sister still as a statue with her bundle still in her hands.
“For you, my lord. A gift.” He bowed and handed the package to Karl.
“Thank you, Piske.” Karl exchanged a rolled parchment for the gift. The container was small, and light. It could have been empty if Karl did not know better. He pulled the string holding everything together, and opened the paper wrapping. Inside was a ring, small and green, with all manner of beasts carved intricately on the sides.
“This is remarkable, Piske. You have my thanks.” Karl said as he turned the ring over in his hands. He spied an eagle, a fish, a rat, and a bear amongst the throng of creatures on the metal.
Piske looked to Lemba, eyes practically screaming for help. Lemba chuckled to himself for a moment and then cocked his head in Karl’s direction.
“May I approach, my lord?” the Elf asked in the elegant Elvish tongue, hands out stretched. Karl nodded his approval and he came forward. Piske leaned forward, taking the ring from the Lord’s hand and slipped the emerald ring onto his own left pointer finger.
“This ring is rather...peculiar, my lord. Observe.” The Elf cleared his throat and began to shout “Will one of you fellows come out? We’d like to make introductions.”
A heavy silence, followed by quiet, confused muttering amongst the onlookers. Then a shriek came from the rear of the crowd, growing louder and closer by the second.
That’s when it appeared before Karl’s eyes. It came forward at a run. Sharp claws, huge black eyes, and jagged yellow teeth.
“The ring summons rats?” Karl answered in Elvish in between laughs.
“Or maybe it makes the wearer forget his manners.” came a perfect Elvish reply from the rat. Karl’s eyes shot wide. Bhalik’s Maw. Did that rodent just speak? He regained his composure and looked around his court. Everyone was staring up at him. Had they all heard too?
“They can’t hear me, you big oaf. Only the ring bearer can.” Karl glanced at the green band around his finger. “My name is difficult to pronounce, but for the sake of simplicity, call me Ymaut. Piske tells me you have a rather large network of informants. How would you like to expand?
“We’ll discuss another time. Thank you, Piske. You honor me.”
Piske bowed. “Of course, my lord. My sister has brought you a gift as well” gesturing to his companion. He stepped back to take her place, while Viksna approached, bowed and held out her tribute. The thing she brought was bigger and heavier than her brother’s gift. When Karl had finished unwrapping it, he understood why.
“A Grimoire.” he said quietly.
“May I approach, my lord?” Karl nodded absently as he flipped through the pages.
Viksna whispered. “I am told you enjoy practicing magic. I would be happy to teach you, if you’d like.”
“This is too much to trade for a mere letter of safe conduct. Anything in my power to give you is yours, if you but name it.”
Viksna thought for only a brief moment. “Should there be an opening for a position in your court that I may be suitable for, I would like to enter your service.”
Lemba is leaving my service, to return to Outland. If you would care to remain here and assume his role upon his departure, I would welcome the company.” Karl said as he struggled to tear his eyes away from the book. That will be all for today. My servants will show you to your chambers. Should you want for anything at all, you need only ask and it is yours.”
The two bowed low. “You honor us, my lord.” the two Elves said as one. As they slowly walked from the hall, Karl’s Chamberlain, Aldred, whispered in his ear. “My lord, Sir Vanya has come to charge Baron Stevers as an oathbreaker. My duty calls. Karl thought, the grimoire still open in his hand.
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2024.05.28 00:43 healthmedicinet Health Daily News May 26 2024

DAY: MAY 26 2024
5-26-2024

AI CHATBOTS ARE INTRUDING INTO ONLINE COMMUNITIES WHERE PEOPLE ARE TRYING TO CONNECT WITH OTHER HUMANS

A parent asked a question in a private Facebook group in April 2024: Does anyone with a child who is both gifted and disabled have any experience with New York City public schools? The parent received a seemingly helpful answer that laid out some characteristics of a specific school, beginning with the context that “I have a child who is also 2e,” meaning twice exceptional. On a Facebook group for swapping unwanted items near Boston, a user looking for specific items received an offer of a “gently used” Canon camera
5-26-2024

MICROSOFT’S AI CHATBOT WILL ‘RECALL’ EVERYTHING YOU DO ON A PC

Microsoft wants laptop users to get so comfortable with its artificial intelligence chatbot that it will remember everything you’re doing on your computer and help figure out what you want to do next. The software giant on Monday revealed a new class of AI-imbued personal
5-26-2024

AI RELIES ON MASS SURVEILLANCE, WARNS SIGNAL BOSS

The AI tools that crunch numbers, generate text and videos and find patterns in data rely on mass surveillance and exercise concerning control over our lives, the boss of encrypted messaging app Signal told AFP on Thursday. Pushing back against the unquestioning enthusiasm at VivaTech in Paris, Europe’s top startup conference where industry players vaunt the merits of their products, Meredith Whittaker said concerns about surveillance and those about AI were “two framings
5-26-2024

THE ‘DEAD INTERNET THEORY’ MAKES EERIE CLAIMS ABOUT AN AI-RUN WEB. THE TRUTH IS MORE SINISTER

An example of a shrimp Jesus image on Facebook with no caption or context information included in the post. Credit: Facebook If you search “shrimp Jesus” on Facebook, you might encounter dozens of images of artificial intelligence (AI) generated crustaceans meshed in various forms with a stereotypical image of Jesus Christ. Some of these hyper-realistic images have garnered more than 20,000 likes and comments. So what exactly is going on here? The “dead internet theory” has an explanation: AI and bot-generated content has surpassed the human-generated internet. But where did
5-26-2024

WHAT ARE DEEPFAKES AND SHOULD WE BE WORRIED?

Deepfakes are creating havoc across the globe, spreading fake news and pornography, being used to steal identities, exploiting celebrities, scamming ordinary people and even influencing elections. Yet a worldwide survey found 71% of people have no idea what deepfakes are. Deepfakes are digital photos, videos or voices of real people that have either been synthetically created or manipulated using artificial intelligence (AI) and can be hard to distinguish from the real thing. You’ve probably seen a deepfake video or photo without even realizing it. Computer-generated Tom Cruises,
5-26-2024

META INTRODUCES CHAMELEON, AN EARLY-FUSION MULTIMODAL MODEL

Chameleon represents all modalities—images, text, and code, as discrete tokens and uses a uniform transformer-based architecture that is trained from scratch in an end-to-end fashion on ?10T tokens of interleaved mixed-modal data. As a result, Chameleon can both reason over, as well as generate, arbitrary mixed-modal documents. Text tokens are represented in green and image tokens are represented in blue. AI researchers at Meta, the company that owns Facebook, Instagram, WhatsApp, and many other products, have designed and built a multimodal model to compete with
5-26-2024

ELECTRIC SCHOOL BUSES MAY YIELD SIGNIFICANT HEALTH AND CLIMATE BENEFITS, COST SAVINGS

Replacing diesel school buses with electric school buses may yield up to $247,600 in climate and health benefits per individual bus, according to a new study by researchers at Harvard T.H. Chan School of Public Health. The researchers found that these benefits—including fewer greenhouse gas emissions and reduced rates of adult mortality and childhood asthma—and their associated savings are strongest in large cities and among fleets of old (2005 and before) buses. The study, “Adopting electric school buses in the United States: health and climate benefits,” was published in the
5-26-2024

WEARABLE DEVICES GET SIGNAL BOOST FROM NEW MATERIAL

Strain-invariant stretchable wireless system enabled by dielectro-elastic composite. A new material that moves like skin while preserving signal strength in electronics could enable the development of next-generation wearable devices with continuous, consistent wireless and battery-free functionality. According to a study published today in Nature, an international team of researchers from Rice University and Hanyang University developed the material by embedding clusters of highly dielectric ceramic nanoparticles into an elastic polymer. The material was reverse-engineered to not only mimic skin elasticity and motion types, but also
5-26-2024

AI DOMINATES ANNUAL PARIS STARTUP EVENT VIVATECH

Vivatech will host more than 150,000 guests, 11,000 startups and 450 speakers over four days. Thousands of tech enthusiasts filed into Europe’s self-declared biggest startup event VivaTech in Paris on Wednesday, with artificial intelligence stealing the show this year. Over four days, the event, now in its eighth year, will host more than 150,000 guests, 11,000 startups and 450 speakers, according to the organizers. The star turns will take to the stage on Thursday—former US climate envoy and secretary of state John Kerry is expected to make a push for
5-26-2024

AI POISED TO USHER IN NEW LEVEL OF CONCIERGE SERVICES TO THE PUBLIC

AI concierge’s fundamental forms. Credit: Journal of Service Management (2024). Concierge services built on artificial intelligence have the potential to improve how hotels and other service businesses interact with customers, a new paper suggests. In the first work to introduce the concept, researchers have outlined the role an AI concierge, a technologically advanced assistant, may play in various areas of the service sector as well as the different forms such a helper might embody. Their paper envisions a virtual caretaker that, by combining natural language processing, behavioral data
5-26-2024

AGE VERIFICATION FOR SOCIAL MEDIA WOULD IMPACT EVERYONE—RESEARCHERS ASK PARENTS AND KIDS IF THEY ACTUALLY WANT IT

by Justine Humphry, Catherine Page Jeffery, Jonathon Hutchinson and Olga Boichak, The Conversation This month the Australian government announced a A$6.5 million commitment to trial an age-verification program that will restrict children’s exposure to inappropriate online content, including pornography and potentially social media. The announcement came out of a National Cabinet meeting geared towards addressing gender-based violence in Australia. Much has been said about age-checking technologies in the weeks since. Experts point out implementing these tools effectively (so they aren’t easily by-passed) will be complicated—and any such system could come
5-26-2024

IS IT SAFE TO FLY? AIRLINE SAFETY EXPERT ON MODERN COMMERCIAL FLIGHT

In light of recent news regarding congressional action on aviation safety, Penn State News spoke with Amy Pritchett, department head of aerospace engineering and professor in Penn State’s College of Engineering. Pritchett previously served as the director of NASA’s Aviation Safety Program and currently chairs the National Academies committee chartered to research and advise federal regulators on emerging trends in aviation safety. In
5-26-2024

USING SMART DEVICES TO SCHEDULE ON-DEMAND PUBLIC TRANSPORTATION CAN SAVE TIME AND MONEY

Suburban residents often face challenges receiving reliable and accessible bus transit—riders often complain about infrequent schedules and long waiting times. Often, transit agencies are unable to provide additional buses because population density in such areas is usually low. On-demand transit (ODT) is an innovative transportation approach that enhances the accessibility and quality of service while reducing operating costs. Despite the rapid growth of ODT services in various cities across Canada and the United States, the mechanism of
5-26-2024

UNDERWATER SIGNALS GENERATED BY OPEN SEA AIRPLANE CRASHES COULD BE KEY TO DETECTING FINAL RESTING PLACE OF MH370

Location of the CTBTO’s hydroacoustic stations H11N and H11S (white triangles); the impact location of three aircrafts (indicated in yellow): F-35a, Transair Flight 810, and Asiana Flight 991; and the distances and bearings relative to the hydroacoustic stations (presented in magenta). The cyan star shows the location of earthquake M 4.8–9 km S of Y?kaichiba, Japan, 2014-03-07 18:34:20 (UTC) 35.611o N 140.552o E 23.9 km depth. Signals captured on underwater microphones could be key to locating airplanes such as MH370 when they crash into
5-26-2024

SURVEY INVESTIGATES AI TECHNOLOGIES IN THE CLASSIFICATION AND CREATION OF ART

A comprehensive survey has looked at the intersection of art and artificial intelligence (AI). The team has focused on how AI technologies are employed in the classification and also the creation of artworks. Andrej Šimi? and Marina Bagi? Babac of the Faculty of Electrical Engineering and Computing at the University of Zagreb have analyzed and categorized a number of research papers in this field to understand the methodologies, techniques, and outcomes in this emerging field. They discuss
5-26-2024

CYBERSECURITY LABELING FOR SMART DEVICES AIMS TO HELP PEOPLE CHOOSE ITEMS LESS LIKELY TO BE HACKED

Smart devices like baby monitors, fitness trackers and internet-connected appliances will soon be eligible for labels certifying that they meet federal cybersecurity standards. Federal officials said Wednesday that the first “Cyber Trust” labels could appear in time for the holiday shopping season. The White House announced the labels last year to help consumers avoid devices that are vulnerable to hacking. Credit: AP Photo/Susan Walsh, File Consumer labels
5-26-2024

WORLD LEADERS STILL NEED TO WAKE UP TO AI RISKS, SAY LEADING EXPERTS AHEAD OF AI SAFETY SUMMIT

Leading AI scientists are calling for stronger action on AI risks from world leaders, warning that progress has been insufficient since the first AI Safety Summit in Bletchley Park six months ago. Then, the world’s leaders pledged to govern AI responsibly. However, as the second AI Safety Summit in Seoul (21–22 May) approaches, 25 of the world’s leading AI scientists say not enough is actually being done to protect us from the technology’s risks. In an expert consensus paper published in Science, they outline urgent policy priorities that global leaders
5-26-2024

MICROSOFT’S AI CHATBOT WILL ‘RECALL’ EVERYTHING YOU DO ON A PC

Microsoft wants laptop users to get so comfortable with its artificial intelligence chatbot that it will remember everything you’re doing on your computer and help figure out what you want to do next. The software giant on Monday revealed a new class of AI-imbued personal
5-26-2024

AI TRAINED TO DRAW INSPIRATION FROM IMAGES, NOT COPY THEM

Powerful new artificial intelligence models sometimes, quite famously, get things wrong—whether hallucinating false information or memorizing others’ work and offering it up as their own. To address the latter, researchers led by a team at The University of Texas at Austin have developed a framework to train AI models on images corrupted beyond recognition. DALL-E, Midjourney and Stable Diffusion are among the text-to-image diffusion generative AI models that can turn arbitrary user text into highly realistic images. All three are now facing lawsuits from artists who
5-26-2024

AI CHIPS COULD GET A SENSE OF TIME WITH MEMRISTOR THAT CAN BE TUNED

Tunable composition and structural disorder in single-crystalline ESO thin films on epitaxial YBCO electrodes. Credit: Nature Electronics (2024). Artificial neural networks may soon be able to process time-dependent information, such as audio and video data, more efficiently. The first memristor with a “relaxation time” that can be tuned is reported today in Nature Electronics, in a study led by the University of Michigan. Memristors, electrical components that store information in their electrical resistance, could reduce AI’s energy needs by about a factor of 90 compared to today’s graphical
5-26-2024

WHAT GOOGLE AI MEANS FOR YOU—AND YOUR SEARCH RESULTS

Google recently unveiled plans to integrate its search engine with artificial intelligence (AI). The company is debuting a new search engine feature called A.I. Overviews, which generates an overview of the topic a user searches and displays links to learn more. Traditional search results still appear underneath, but A.I. Overviews, Google says, will parse various pieces of information to give you a quicker answer. The new feature has raised concerns from some web publishers, who worry it will deal a heavy blow to their site traffic. Currently, A.I. Overviews don’t
5-26-2024

RESEARCHERS ANALYZE THE CHARACTERISTICS OF AI-GENERATED DEEPFAKES

Credit: AI-generated image Most of the deepfakes (videos with fake hyper-realistic recreations) generated by artificial intelligence (AI) that spread through social media feature political representatives and artists and are often linked to current news cycles. This is one of the conclusions of research by the Universidad Carlos III de Madrid (UC3M) that analyzes the formal and content characteristics of viral misinformation in Spain arising from the use of AI tools for illicit purposes. This advance represents a step towards understanding and mitigating the threats generated by hoaxes in our society.
5-26-2024

INTERDISCIPLINARY GROUP SUGGESTS GUIDELINES FOR THE USE OF AI IN SCIENCE

(AI) generates texts, videos and images that can hardly be distinguished from those of humans—with the result that we often no longer know what is real. Researchers and scientists are increasingly being supported by AI. Therefore, an international task force has now developed principles for
5-26-2024

IMPERCEPTIBLE SENSORS MADE FROM ‘ELECTRONIC SPIDER SILK’ CAN BE PRINTED DIRECTLY ON HUMAN SKIN

Researchers have developed a method to make adaptive and eco-friendly sensors that can be directly and imperceptibly printed onto a wide range of biological surfaces, whether that’s a finger or a flower petal. Credit: University of Cambridge Researchers have developed a method to make adaptive and eco-friendly sensors that can be directly and imperceptibly printed onto a wide range of biological surfaces, whether that’s a finger or a flower petal. The method, developed by researchers from the University of Cambridge, takes its inspiration from spider silk, which can conform and
5-26-2024

BREAKTHROUGH OR BOAST? THE QUEST FOR COMPARABLE RESEARCH RESULTS

More international attention is being paid to the importance of common standards for performing scientific experiments and measuring their results—a field called metrology. In late 2019, physicist Dr. Lorenzo Pattelli was part of an Italian-Chinese scientific team working on a cooling technology that is fast gaining attention as the Earth gets hotter from climate change. Called passive daytime radiative cooling, or PDRC, the technology uses engineered materials to reflect away the sun’s radiation. The idea is that, amid heat waves, PDRC panels would cool buildings without the need for energy-intensive
5-26-2024

AI-ENHANCED COLLECTIVE BARGAINING TOOLS COULD HELP GIG WORKERS SOLVE PROBLEMS

Researchers at Northeastern University have created artificial intelligence tools to help gig workers organize, collect their own job-related data, analyze their work problems and come up with a strategy to implement solutions. “Building solid AI-enhanced solutions to enable gig workers’ collective action will pave the way for a fair and ethical gig economy—one with fair wages, humane working conditions and increased job security,” says Saiph Savage, assistant professor and director of the Civic A.I. Lab at Northeastern’s Khoury College of Computer Sciences. Gig work is typically performed by a freelancer
5-26-2024

AI-POWERED TRADING STRATEGIES TAME MARKET SWINGS

Average financial indicators feature importance. Credit: Quantitative Finance and Economics (2024). DOI: 10.3934/QFE.2024007 The dynamic landscape of cryptocurrencies, marked by rapid growth and high volatility since Bitcoin’s inception in 2009, has attracted significant attention from investors and traders. The emergence of new digital currencies challenges traditional financial models, necessitating advanced analytical tools to navigate the market’s unpredictability. The quest for effective trading strategies has led to the exploration of AI and machine learning techniques, which promise to enhance decision-making in this speculative yet lucrative field. Researchers from the University of
5-26-2024

NEW ROBOTIC PALM USES SOPHISTICATED TACTILE SENSORS TO MIMIC HUMAN TOUCH

“I’ll have you eating out of the palm of my hand” is an unlikely utterance you’ll hear from a robot. Why? Most of them don’t have palms. If you have kept up with the protean field, gripping and grasping more like humans has been an ongoing Herculean effort. Now, a new robotic hand design developed in MIT’s Computer Science and Artificial Intelligence Laboratory (CSAIL) has rethought the oft-overlooked
5-26-2024

SCARLETT JOHANSSON SAYS A CHATGPT VOICE IS ‘EERILY SIMILAR’ TO HERS AND OPENAI IS HALTING ITS USE

Scarlett Johansson poses for photographers at the photo call for the film “Asteroid City” at the 76th international film festival, Cannes, southern France, May 24, 2023. OpenAI plans to halt the use of one of its ChatGPT voices after some drew similarities to Johansson, who famously portrayed a fictional AI assistant in the (perhaps no longer so futuristic) film “Her.” File OpenAI on Monday said it plans to halt the use of one of its ChatGPT voices that “Her” actor Scarlett Johansson says sounds
5-26-2024

AI HEADPHONES LET WEARER LISTEN TO A SINGLE PERSON IN A CROWD BY LOOKING AT THEM JUST ONCE

A University of Washington team has developed an artificial intelligence system that lets a user wearing headphones look at a person speaking for three to five seconds and then hear just the enrolled speaker’s voice in real time even as the listener moves around in noisy places and no longer faces the speaker. Pictured is a prototype of the headphone system: binaural microphones attached to off-the-shelf noise canceling headphones. Credit: Kiyomi Taguchi/University of Washington Noise-canceling headphones have gotten very good at creating an auditory blank slate. But allowing certain sounds
5-26-2024

NVIDIA’S PROFIT SOARS, UNDERSCORING ITS DOMINANCE IN CHIPS FOR ARTIFICIAL INTELLIGENCE

Nvidia reports earnings on Wednesday, May 22, 2024. Credit: AP Photo/Eric Risberg Nvidia on Wednesday overshot Wall Street estimates as its profit skyrocketed, bolstered by the chipmaking dominance that has made the company an icon of the artificial intelligence boom. Its net income rose more than sevenfold compared to a year earlier, jumping to $14.88 billion in its first quarter that ended April 28 from $2.04 billion a year earlier. Revenue
5-26-2024

EIT-BASED TACTILE SENSOR PROVIDES NEW APPROACH TO FINE MOTOR SKILLS ASSESSMENT

Researchers from SIT Japan showed a peg-shaped sensor for classifying adult pinching motions. Reconstructed images reach 79.4% accuracy, while voltage vectors achieve 91.4%, hinting at automated finger motion analysis potential. a) The microcontroller and sensing device are connected by a wire. (b) Hand model pinching the sensing device with two fingers from the horizontal direction and the reconstructed image. Credit: Hiroki Sato from SIT, Japan. Fine motor skills play a crucial role in human cognition, influencing everything from daily activities to the development of advanced tool-based civilizations. Yet, quantifying and
5-26-2024

EUROPE’S CLIMATE LAWS COULD SPELL THE END TO LOW-COST FLIGHTS—BUT WHAT ABOUT PRIVATE JETS?

The era of low-cost air travel in Europe may be over for good, thanks in part to recent EU environmental policies. All in all, this is good news for the climate. But many low- and middle-income people who used to travel around the EU will no longer be able to do so, or at least will be able to do so much less often. Yet the same policies will have little or no impact on the use of much more polluting private jets, which typically cover distances served by commercial
5-26-2024

ROBOT-PHOBIA COULD EXASPERATE HOTEL, RESTAURANT LABOR SHORTAGE

Using more robots to close labor gaps in the hospitality industry may backfire and cause more human workers to quit, according to a Washington State University study. The study, involving more than 620 lodging and food service employees, found that “robot-phobia”—specifically the fear that robots and technology will take human jobs—increased workers’ job insecurity and stress, leading to greater intentions to leave their jobs. The impact was more pronounced with employees who had real experience working with robotic technology. It also affected managers in addition to frontline workers. The findings
5-26-2024

TWO TYPES OF LLMS FOUND ABLE TO EQUAL OR OUTPERFORM HUMANS ON THEORY OF MIND TESTS

Performance of human (purple), GPT-4 (dark blue), GPT-3.5 (light blue) and LLaMA2-70B (green) on the battery of theory of mind tests. a, Original test items for each test showing the distribution of test scores for individual sessions and participants. b, Interquartile ranges of the average scores on the original published items (dark colors) and novel items (pale colors) across each test. An international team of psychologists and neurobiologists has found via experimentation that two types of LLMs are able to equal or outperform
5-26-2024

SANOFI ALLIES WITH OPENAI, FORMATION BIO FOR AI USE IN DRUG DEVELOPMENT

AI is playing an ever greater role in developing new medicines, as well as identifying new applications for existing drugs. French pharmaceutical company Sanofi announced Tuesday a partnership with ChatGPT-founder OpenAI and US biotech firm Formation Bio to accelerate the use of artificial intelligence in developing drugs. AI is playing an ever greater role in developing new medicines, as well as identifying new applications for existing drugs. It can be used for example to find new molecules more quickly and to improve clinical tests by vetting which patients would be
5-26-2024

USING AI, MASTERCARD EXPECTS TO FIND COMPROMISED CARDS QUICKER, BEFORE THEY GET USED BY CRIMINALS

A sign indicating MasterCard credit cards are accepted is posted at a New York business, Jan. 21, 2015. Mastercard said Wednesday, May 21, 2024, that it expects to be able to discover that your credit or debit card number has been compromised well before it ends up in the hands of a cybercriminal. Credit: AP Photo/Mark Lennihan, File Mastercard said Wednesday that it expects to be able to discover that your credit or debit card number has been compromised well before it ends up in the hands of a cybercriminal.
5-26-2024

NEW FLEXIBLE FILM DETECTS EYELASH PROXIMITY IN BLINK-TRACKING GLASSES

When attached to eyeglasses, a clear, flexible sensor can detect how close eyelashes are to the lens, enabling blink tracking. When another person’s finger hovers over your skin, you may get the sense that they’re touching you, feeling not necessarily contact, but their proximity. Similarly, researchers reporting in ACS Applied Materials & Interfaces have designed a soft, flexible film that senses the presence of nearby objects without physically touching them. The study features the new sensor technology to detect
5-26-2024

GAMERS SAY THEY HATE ‘SMURFING,’ BUT ADMIT THEY DO IT

Online video game players believe the behavior known as “smurfing” is generally wrong and toxic to the gaming community—but most admit to doing it and say some reasons make the behavior less blameworthy, new research finds. The new study suggests that debates about toxicity in gaming may sometimes be more complex and nuanced than is often acknowledged, according to the researchers. Online video games use what are called “matchmaking systems” to pair players based on skill. “Smurfing” is when players cheat these systems by creating new accounts so that they
5-26-2024

HUMANS BARELY ABLE TO RECOGNIZE AI-GENERATED MEDIA

AI-generated images, texts and audio files are so convincing that people are no longer able to distinguish them from human-generated content. This is the result of an online survey of about 3,000 participants from Germany, China, and the U.S. This is the first time that a large transnational study has examined this particular form of media literacy.
5-26-2024

CAN AIRPLANE TURBULENCE REALLY KILL YOU? AIRCRAFT PROPULSION EXPERT WEIGHS IN ON SINGAPORE AIRLINES DEATH

One person was killed and several dozen more injured Tuesday when a flight from London to Singapore encountered “sudden extreme turbulence” and plummeted roughly 6,000 feet in a matter of minutes, according to The Washington Post. All told, there were 211 passengers and 18 crew on board, according to Singapore Airlines. The deceased passenger reportedly suffered a heart attack during the mid-air tumult. The Boeing 777-300ER operated by Singapore Airlines diverted to Bangkok, where it landed at 3:45 p.m. local time on Tuesday following the in-flight incident. The New York
5-26-2024

HOW INTELLIGENCE AGENCIES’ ARE CAUTIOUSLY EMBRACING GENERATIVE AI

U.S. intelligence agencies are scrambling to embrace the AI revolution, convinced they’ll otherwise be smothered in data as sensor-generated surveillance tech further blankets the planet. They also need to keep pace with competitors, who are already using AI to seed social media platforms with deepfakes. But the tech is young and brittle, and officials are acutely aware that generative AI is anything but tailor-made for a trade steeped in danger and deception. Years before OpenAI’s ChatGPT set off the current generative AI marketing frenzy, U.S. intelligence and defense officials were
5-26-2024

3D PRINTING ROBOT USES AI MACHINE LEARNING TO CREATE A SHOCK-ABSORBING SHAPE NO HUMAN EVER COULD

Inside a lab in Boston University’s College of Engineering, a robot arm drops small, plastic objects into a box placed perfectly on the floor to catch them as they fall. One by one, these tiny structures—feather-light, cylindrical pieces, no bigger than an inch tall—fill the box. Some are red, others blue, purple, green, or black. Each object is the result of an experiment in robot autonomy. On its own, learning as it goes, the robot is searching for, and trying to make, an object with the most
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