Discontinuing lipitor
My Covid and Paxlovid experience
2024.03.28 07:11 GromitInWA My Covid and Paxlovid experience
Tested positive on Friday a week and a half ago having had a bit of a sore throat the day before and feeling a bit off. I used a lateral flow test that was several months past its expiration date, but it went positive in under 2 minutes…
On Saturday, I had a slight fever and I got a Paxlovid prescription via a telehealth appointment (free in Washington state) and was advised to discontinue medications that I was on (Zyrtec for allergies, Dulera for asthma and Lipitor) as well as to avoid herbal medicines. Actually getting the prescription filled was harder than I had hoped since the first pharmacy did not have it and suggested I phone around to find one that did. I was concerned about the cost as I had read that it could be upwards of $1000, but my prescription insurance website said it would be <$100 and it actually turned out to be a copay of $25. Pfizer has some sort of discount card that you can get online, but I did not use it. I took the first dose that evening. I was also taking vitamin C, electrolytes and those immune shot things with ginger.
On Tuesday (Day 5) I tested negative and continued to test negative the next two days. Wednesday was my last Paxlovid dose.
Between the first and last Paxlovid doses, I had a bunch of symptoms: the sour taste that seemed to be more acute shortly after taking the dose, also lighter colored stools. I also had what I assume were Covid symptoms and quite possibly seasonal allergies particularly as I was off the Zyrtec.
Hopefully this is useful information for others. Note that I have had Covid twice before and was fully up on date on vaccinations (though had just been offered the latest booster, which I guess I won’t bother with). My main reason for taking Paxlovid was to shorten the duration and to reduce the risk of long Covid.
submitted by GromitInWA to COVID19positive [link] [comments]
On Saturday, I had a slight fever and I got a Paxlovid prescription via a telehealth appointment (free in Washington state) and was advised to discontinue medications that I was on (Zyrtec for allergies, Dulera for asthma and Lipitor) as well as to avoid herbal medicines. Actually getting the prescription filled was harder than I had hoped since the first pharmacy did not have it and suggested I phone around to find one that did. I was concerned about the cost as I had read that it could be upwards of $1000, but my prescription insurance website said it would be <$100 and it actually turned out to be a copay of $25. Pfizer has some sort of discount card that you can get online, but I did not use it. I took the first dose that evening. I was also taking vitamin C, electrolytes and those immune shot things with ginger.
On Tuesday (Day 5) I tested negative and continued to test negative the next two days. Wednesday was my last Paxlovid dose.
Between the first and last Paxlovid doses, I had a bunch of symptoms: the sour taste that seemed to be more acute shortly after taking the dose, also lighter colored stools. I also had what I assume were Covid symptoms and quite possibly seasonal allergies particularly as I was off the Zyrtec.
Hopefully this is useful information for others. Note that I have had Covid twice before and was fully up on date on vaccinations (though had just been offered the latest booster, which I guess I won’t bother with). My main reason for taking Paxlovid was to shorten the duration and to reduce the risk of long Covid.
2023.10.25 22:03 smamler Starting on Pax asap 55M diabetic any tips?
Hi I am on day 2 of Covid. I just talked to my dr and got an Rx of Pax to start asap.
Can anyone in my age group give me a sense of what it’s going to be like?
Diarrhea? Weird dry mouth taste? Other things?
I’m probably (based on what I’ve read and what my dr said—pharmacist may have more to say) going to discontinue Lipitor and weekly ozempic while on pax, any symptoms there?
Thank you Reddit.
submitted by smamler to paxlovid [link] [comments]
Can anyone in my age group give me a sense of what it’s going to be like?
Diarrhea? Weird dry mouth taste? Other things?
I’m probably (based on what I’ve read and what my dr said—pharmacist may have more to say) going to discontinue Lipitor and weekly ozempic while on pax, any symptoms there?
Thank you Reddit.
2023.10.16 07:24 veryscared2023 40m - started rosuvastatin 20mg ~4 weeks ago, now experiencing dizziness/loss of balance/tiredness and cluster (icepick?) headaches. Should I ride this out and see if it gets better?
Hi,
40m. I had a cardiac stent implanted in August 2022 as therapy for a 75% blockage. I have not suffered a heart attack or a stroke. Upon discharge I started lipitor 20g, metoprolol 50mg, plavix and aspirin.
Things were fine for a year until august of this year: I experienced leg cramps, shooting pains all over my body, tingling and numbness and perceived weakness in my extremities, as well as periodic muscle twitching. My PCP moved me to rosuvastatin and started me on CoQ10 at the beginning of Sempter. Over the past couple of weeks I developed the symptoms in the title.
My lipids as of July 2023: total cholesterol: 126 triglycerides: 111 chol/hdlc ratio: 3.0 hdl: 42 ldl: 65 non hdl: 84
I have half a mind to discontinue the rosuvastatin until I receive further advisement from my doctor, or else cut the pill in half and take 10mg.
Should I continue taking the full 20mg? Should I stop and wait to see what he says? Should I start taking lipitor again (I still have the pills).
Thanks for your time and for choosing to save lives as your careers.
submitted by veryscared2023 to AskDocs [link] [comments]
40m. I had a cardiac stent implanted in August 2022 as therapy for a 75% blockage. I have not suffered a heart attack or a stroke. Upon discharge I started lipitor 20g, metoprolol 50mg, plavix and aspirin.
Things were fine for a year until august of this year: I experienced leg cramps, shooting pains all over my body, tingling and numbness and perceived weakness in my extremities, as well as periodic muscle twitching. My PCP moved me to rosuvastatin and started me on CoQ10 at the beginning of Sempter. Over the past couple of weeks I developed the symptoms in the title.
My lipids as of July 2023: total cholesterol: 126 triglycerides: 111 chol/hdlc ratio: 3.0 hdl: 42 ldl: 65 non hdl: 84
I have half a mind to discontinue the rosuvastatin until I receive further advisement from my doctor, or else cut the pill in half and take 10mg.
Should I continue taking the full 20mg? Should I stop and wait to see what he says? Should I start taking lipitor again (I still have the pills).
Thanks for your time and for choosing to save lives as your careers.
2023.08.20 16:14 raedems Bipolar 1 Disorder, recent psych hospital admission from SSRI
I'm posting this to share my experience with an adverse side effect from Prozac. Maybe me posting about it will help inform others of this problematic situation.
I recently saw my psychiatrist ARNP and told her about my experience with negative intrusive thoughts and me often saying "I love you, MY NAME," I love you Meemaw, Zeus (who is my dog), Meemaw. I did say these things quite often so it was like an OCD behavior. I also play World of Warcraft, Eve Online, or some other games for quite a few hours daily as it seems to help me cope. Anyways, I was prescribed Prozac and from the very first dose I had significant problems. I had trouble sleeping and waking up very early like 2:15Am -3:30 AM. I do have sleep apnea and use my bipap regularly whenever I'm asleep. I woke up extremely irritable and wanted to unload on my mom that early morning. I did my best to quell those irritations and subsequent actions. So that was the first day, the next one or 2 pills I continued having problems with sleep but the accute irritation seemed to subside. I looked up prozac and saw that it had a long halflife like 5 days or so. SO I tried to wait a few days before the next dose. On the 4th or 5th pill altogether of Prozac, I began having psychosis to include paranoia and delusions. I threw away the remaining month of meds into the trash can after that.
I went and informed a therapist at the psych clinic of this adverse side effect. Their were no doctor's or ARNP's that I could talk to as that day they are at a location on other side of the county. I informed the therapist she thought I did the right thing in stopping the medicine but also emailed the ARNP about the problem. I wasn't suicidal or homicidal. So she couldn't do anything except calm me down and set up a therapist intake appointment. I complied.
The next day, I woke up very paranoid and delusional. I asked my mom to drive me to Psych Hospital where I voluntarily admitted myself. The psychotic features were mood-congruent with most recent bipolar episode as manic. The paranoia and delusions centered around the police, me searching my own name, the guild im in on WOW/Discord, my favorite Book series on Discord. I would read into things that were posted online whether that be in guild chat or discord chat. After a week of being at the psychiatric hospital I got much better. Prozac was discontinued which I had thought was the problem as there weren't any relationship problems or other things that contributed to it. My medications were otherwise unchanged much besides the fluoxetine, though Remeron was added to my med list. It really did help with my sleep and mood. I greatly recommend Remeron for other bipolar patients. It seemed many other bipolars on the unit were getting prescribed it and it was really helping their sleep too.
I'm writing this to continue making my case study available on the internet perhaps to help others understand bipolar disorder, or at least my case of it, better. I have posted other occasions on the internet as well even on reddit but I think they were taken down and I can't find my usernames etc that I had before but I may have simply cancelled those accounts.
My med list is: Remeron 15mg, Seroquel 400mg, Wellbutrin 150 mg, Lamictal 400mg, Crestor 5mg, Lisinopril 5mg, Metformin 1000mg.
My feedback and experience with some of these medicines and/or others are described as follows: For Seroquel I would often have racing heartbeat at 400mg+. I informed my doctor that I could tolerate more of it after having been diagnosed and treated for sleep apnea. He was wondering why I was having racing heartbeat and informed him of this finding that it was likely sleep apnea that was flaring up after having been given seroquel. The next medicine I found somewhat problematic is getting Wellbutrin at 300mg. I'd often have problems with insomnia at that dosage so preferred the lower 150mg dose. Finally my last interesting finding that I would like to make public is that of being prescribed Lipitor. With Lipitor I experienced increasingly problematic insomnia even after just a few doses of it. I also experienced a burnt smell when taking it. The last time I had experienced a burnt smell was when I was 19 during my first mental breakdown. I sort of have been on the lookout for that symptom as sometimes it could be an olfactory hallucination. Anyways, I experienced it again with Lipitor. The doctor changed it to Crestor and I was fine with it. I have also tried Zocor with no issues either. I did look up burnt smells and saw that it could be related to small seizure or problems with the liver, so I thought that might be interesting. In anycase when I told my Pulmonologist of the insomnia with Lipitor he mentioned that he had many clients with insomnia when taking statins and that he would have patients discontinue statins a few days prior to them having sleep studies done.
I know that I'm putting lots of medical information public but I hope that if there are any clues into any of this into bipolar disorder that the experts besides my doctors be made aware. I had at one time wanted to be a psychiatrist but my cognitive problems and issues with bipolar disorder absolutely prevented me from that occupation. So, I hope more psychiatrist are made aware of sleep apnea being associated with bipolar disorder or at least for treatment resistant bipolar disorder. I know I had a friend at Celebrate Recovery who has Schizoaffective Disorder that hadn't been diagnosed with sleep apnea until I told him of my situation and recommendation that he get tested for it. He did, and he had it. My pulmonologist mentioned that doctors were finding many more cases of sleep apnea being tied up with mental illnesses.
I know after having been diagnosed and treated for sleep apnea, I became much less interested in finding out about my disorder as I finally believed i had found the main piece that was giving me so much trouble. I on a few occassions had gone to the ER for racing heartbeat, heart palpitations, anxiety, and insomnia. They never considered sleep apnea as a cause for it there but just labeled it as to do with bipolar disoder. After sleep apnea treatment, I became much more active and willing to go outside of my house and experience life again. I have had some problems that have arisen after but i've been able to cope or at least endure on those occasions..
I had kept a record of all of my medical/pschiatric records and have provided copies of those to my primary care doctor but I have since thrown away my personal ones. I sorta have regret in throwing them away because I sorta wish I could have donated them for bipolar research. Maybe I'm exaggerating their use but I do know that sometimes people are selected for case studies and investigations into bipolar disorder. I know I have had MRI's and CT scans in the past too.
One idea I have had recently is that the finding that the ventricles are larger in schizophrenics/bipolar disorder may be associated with sleep apnea affects. Are there any scientific investigations on the effect of sleep apnea on size of ventricles, or other areas of the brain that might tie sleep apnea into some of the structural brain findings for mentally ill patients.
Finally, I had an occasion where I went to see a Neurologist due to movement issues upon waking. I started having rather problematic issues of imbalance with my legs and staggering upon waking as I got out of bed and was walking. I would almost or sometimes glancingly did run into walls. I knew for a fact that that isn't bipolar disorder or a mental illness. So I saw the Neurologist who performed an exam and found nothing. She even had a EMG done for my legs that didn't show any apparent problem. She did have me get a sleep study done and the one thing that she finally did find was the sleep apnea. With treatment that issue has been resolved. SO again, perhaps this will help future doctors find the problem a bit faster.
Hopefully this has been informative. It has at least allowed me to express myself and report these 'findings'. I certainly can't investigate it myself as it would be too much for me to delve into and would probably cause symptoms to worsen. Oh, one other thing that the Neurologist said which I found interesting is that she came to the belief or thought that bipolar disorder is a brain type. That many successful people have had it. I tend to agree with the brain type but that there are medical issues tied into it that need to get addressed for the patient to perform at their best.
TY, bye. Any comments?
submitted by raedems to AskPsychiatry [link] [comments]
I recently saw my psychiatrist ARNP and told her about my experience with negative intrusive thoughts and me often saying "I love you, MY NAME," I love you Meemaw, Zeus (who is my dog), Meemaw. I did say these things quite often so it was like an OCD behavior. I also play World of Warcraft, Eve Online, or some other games for quite a few hours daily as it seems to help me cope. Anyways, I was prescribed Prozac and from the very first dose I had significant problems. I had trouble sleeping and waking up very early like 2:15Am -3:30 AM. I do have sleep apnea and use my bipap regularly whenever I'm asleep. I woke up extremely irritable and wanted to unload on my mom that early morning. I did my best to quell those irritations and subsequent actions. So that was the first day, the next one or 2 pills I continued having problems with sleep but the accute irritation seemed to subside. I looked up prozac and saw that it had a long halflife like 5 days or so. SO I tried to wait a few days before the next dose. On the 4th or 5th pill altogether of Prozac, I began having psychosis to include paranoia and delusions. I threw away the remaining month of meds into the trash can after that.
I went and informed a therapist at the psych clinic of this adverse side effect. Their were no doctor's or ARNP's that I could talk to as that day they are at a location on other side of the county. I informed the therapist she thought I did the right thing in stopping the medicine but also emailed the ARNP about the problem. I wasn't suicidal or homicidal. So she couldn't do anything except calm me down and set up a therapist intake appointment. I complied.
The next day, I woke up very paranoid and delusional. I asked my mom to drive me to Psych Hospital where I voluntarily admitted myself. The psychotic features were mood-congruent with most recent bipolar episode as manic. The paranoia and delusions centered around the police, me searching my own name, the guild im in on WOW/Discord, my favorite Book series on Discord. I would read into things that were posted online whether that be in guild chat or discord chat. After a week of being at the psychiatric hospital I got much better. Prozac was discontinued which I had thought was the problem as there weren't any relationship problems or other things that contributed to it. My medications were otherwise unchanged much besides the fluoxetine, though Remeron was added to my med list. It really did help with my sleep and mood. I greatly recommend Remeron for other bipolar patients. It seemed many other bipolars on the unit were getting prescribed it and it was really helping their sleep too.
I'm writing this to continue making my case study available on the internet perhaps to help others understand bipolar disorder, or at least my case of it, better. I have posted other occasions on the internet as well even on reddit but I think they were taken down and I can't find my usernames etc that I had before but I may have simply cancelled those accounts.
My med list is: Remeron 15mg, Seroquel 400mg, Wellbutrin 150 mg, Lamictal 400mg, Crestor 5mg, Lisinopril 5mg, Metformin 1000mg.
My feedback and experience with some of these medicines and/or others are described as follows: For Seroquel I would often have racing heartbeat at 400mg+. I informed my doctor that I could tolerate more of it after having been diagnosed and treated for sleep apnea. He was wondering why I was having racing heartbeat and informed him of this finding that it was likely sleep apnea that was flaring up after having been given seroquel. The next medicine I found somewhat problematic is getting Wellbutrin at 300mg. I'd often have problems with insomnia at that dosage so preferred the lower 150mg dose. Finally my last interesting finding that I would like to make public is that of being prescribed Lipitor. With Lipitor I experienced increasingly problematic insomnia even after just a few doses of it. I also experienced a burnt smell when taking it. The last time I had experienced a burnt smell was when I was 19 during my first mental breakdown. I sort of have been on the lookout for that symptom as sometimes it could be an olfactory hallucination. Anyways, I experienced it again with Lipitor. The doctor changed it to Crestor and I was fine with it. I have also tried Zocor with no issues either. I did look up burnt smells and saw that it could be related to small seizure or problems with the liver, so I thought that might be interesting. In anycase when I told my Pulmonologist of the insomnia with Lipitor he mentioned that he had many clients with insomnia when taking statins and that he would have patients discontinue statins a few days prior to them having sleep studies done.
I know that I'm putting lots of medical information public but I hope that if there are any clues into any of this into bipolar disorder that the experts besides my doctors be made aware. I had at one time wanted to be a psychiatrist but my cognitive problems and issues with bipolar disorder absolutely prevented me from that occupation. So, I hope more psychiatrist are made aware of sleep apnea being associated with bipolar disorder or at least for treatment resistant bipolar disorder. I know I had a friend at Celebrate Recovery who has Schizoaffective Disorder that hadn't been diagnosed with sleep apnea until I told him of my situation and recommendation that he get tested for it. He did, and he had it. My pulmonologist mentioned that doctors were finding many more cases of sleep apnea being tied up with mental illnesses.
I know after having been diagnosed and treated for sleep apnea, I became much less interested in finding out about my disorder as I finally believed i had found the main piece that was giving me so much trouble. I on a few occassions had gone to the ER for racing heartbeat, heart palpitations, anxiety, and insomnia. They never considered sleep apnea as a cause for it there but just labeled it as to do with bipolar disoder. After sleep apnea treatment, I became much more active and willing to go outside of my house and experience life again. I have had some problems that have arisen after but i've been able to cope or at least endure on those occasions..
I had kept a record of all of my medical/pschiatric records and have provided copies of those to my primary care doctor but I have since thrown away my personal ones. I sorta have regret in throwing them away because I sorta wish I could have donated them for bipolar research. Maybe I'm exaggerating their use but I do know that sometimes people are selected for case studies and investigations into bipolar disorder. I know I have had MRI's and CT scans in the past too.
One idea I have had recently is that the finding that the ventricles are larger in schizophrenics/bipolar disorder may be associated with sleep apnea affects. Are there any scientific investigations on the effect of sleep apnea on size of ventricles, or other areas of the brain that might tie sleep apnea into some of the structural brain findings for mentally ill patients.
Finally, I had an occasion where I went to see a Neurologist due to movement issues upon waking. I started having rather problematic issues of imbalance with my legs and staggering upon waking as I got out of bed and was walking. I would almost or sometimes glancingly did run into walls. I knew for a fact that that isn't bipolar disorder or a mental illness. So I saw the Neurologist who performed an exam and found nothing. She even had a EMG done for my legs that didn't show any apparent problem. She did have me get a sleep study done and the one thing that she finally did find was the sleep apnea. With treatment that issue has been resolved. SO again, perhaps this will help future doctors find the problem a bit faster.
Hopefully this has been informative. It has at least allowed me to express myself and report these 'findings'. I certainly can't investigate it myself as it would be too much for me to delve into and would probably cause symptoms to worsen. Oh, one other thing that the Neurologist said which I found interesting is that she came to the belief or thought that bipolar disorder is a brain type. That many successful people have had it. I tend to agree with the brain type but that there are medical issues tied into it that need to get addressed for the patient to perform at their best.
TY, bye. Any comments?
2023.05.30 19:19 WinnerNo3497 Recently Diagnosed
M29/6’1 ft/220 lbs.
On April 27th of this year, I was diagnosed with some type of Fatty Live disease. Went to my GP for RUQ abdominal pain. Bloodwork was normal with the exception of elevated ALT/AST of 85/116 respectively. No Jaundice or other hepatic symptoms. All kinds of crazy blood tests showed no crazy antibodies, hepatitis, etc.
Based on this result, I did an abdominal ultrasound which showed my liver enlarged to 17.7cm instead of the normal 14.4cm. No other abnormalities identified.
After some lifestyle/medication changes, my latest ALT/AST came down to 54 for both metrics, which is slightly above normal.
I previously took Lipitor for higher cholesterol, but discontinued it based on my liver enzyme finding. I take Zoloft for anxiety and allergy pills/spray.
In addition, I quit drinking and switched to cannabis + non alcoholic beer, and started a HIIT training class 4x/wk.
Despite these changes, I still have RUQ dull pain, feeling frustrated and a little concerned.
I eat generally healthy and exercise
A few questions:
submitted by WinnerNo3497 to FattyLiverNAFLD [link] [comments]
On April 27th of this year, I was diagnosed with some type of Fatty Live disease. Went to my GP for RUQ abdominal pain. Bloodwork was normal with the exception of elevated ALT/AST of 85/116 respectively. No Jaundice or other hepatic symptoms. All kinds of crazy blood tests showed no crazy antibodies, hepatitis, etc.
Based on this result, I did an abdominal ultrasound which showed my liver enlarged to 17.7cm instead of the normal 14.4cm. No other abnormalities identified.
After some lifestyle/medication changes, my latest ALT/AST came down to 54 for both metrics, which is slightly above normal.
I previously took Lipitor for higher cholesterol, but discontinued it based on my liver enzyme finding. I take Zoloft for anxiety and allergy pills/spray.
In addition, I quit drinking and switched to cannabis + non alcoholic beer, and started a HIIT training class 4x/wk.
Despite these changes, I still have RUQ dull pain, feeling frustrated and a little concerned.
I eat generally healthy and exercise
A few questions:
- Any experience with statins and NAFLD? I’m wondering if my cholesterol will be up next time I test.
- I’ve noticed some people on this subreddit mentioning Keto. I love carbs so looking to avoid that but will do if necessary. Any experience with not cutting carbs?
- I presume that since my liver is larger than normal, that I have inflammation (NASH)? Is that the correct assumption? What makes fatty liver NASH?
- Any thoughts on cannabis/Delta 8 use with fatty liver? I only do edibles, I understand that cannabis has anti inflammatory properties, but I also wonder if there’s risk with chemical byproducts in the edible manufacturing process.
- Any experience with liver supplements like NAC?
- How do I know if my fatty liver is caused by my diet, or drinking/supplements/prescriptions?
- Any general comments on my observations? I feel paranoid about this, but I’m surprised to have this in my 20’s
2022.09.03 09:54 sidx46x Why Do Men Lose Hair? Main Causes Of Baldness
 | If your hairline is receding or your crown is thinning, you may be wondering why this is occurring and what is causing your thinning hair. submitted by sidx46x to u/sidx46x [link] [comments] You might also be considering whether there is anything you can do to stop this pattern. Read on to learn more about the reasons why men lose their hair and the treatments that may help slow down the balding process. https://www.docsmart.in/ What causes baldness in men?The vast majority of men who go bald do so because of a hereditary condition known as androgenetic alopecia, more commonly known as male pattern baldness.According to the American Hair Loss Association, 95 percent of hair loss in men is caused by androgenetic alopecia. This inherited trait that tends to give guys a receding hairline and a thinning crown is caused by genetic sensitivity to a byproduct of testosterone called dihydrotestosterone (DHT). So, how exactly does this hormonal byproduct cause hair loss? Well, hair follicles that are sensitive to DHT have a tendency to shrink over time. As the affected hair follicles get smaller, the life span of each hair becomes shorter. Eventually, the affected follicles stop producing hair, or at least the type of hair you’re used to. With male pattern baldness, hair loss typically follows a predictable pattern. The two most common patterns of hair loss include the following:
Although male pattern baldness is the leading cause of balding, it isn’t the only condition that can trigger hair loss. With male pattern baldness, you typically don’t have other symptoms aside from thinning hair. But with other hair loss causes, you may notice you have other symptoms, too. Also, with most other causes, there isn’t always a predictable hair loss pattern like there is with male pattern baldness. Instead, hair loss is more likely to happen all over, or in a few spots. The following conditions can cause varying degrees of hair loss. Some types of hair loss may be permanent, while others may be reversible:
Medications that may cause hair lossHair loss from certain medications is usually temporary and once you stop taking the medication, hair growth will likely resume. Some of the known drugs associated with hair loss include:
Can baldness be prevented?Male pattern baldness is commonly an inherited condition. It’s very difficult to non surgically reverse any of the hair loss that’s seen with this condition.However, preventing further hair loss at the first sign of thinning is possible. Finasteride and Rogaine are two known treatments that might prevent further hair loss seen with androgenetic alopecia. Once you discontinue use of these medications, the hair loss may resume. Talk to your doctor about if these medications may be right for you. To keep your hair healthy and to prevent hair loss from other causes, try the following:
https://www.docsmart.in/ ConclusionIf you have a bald spot or a receding hairline, it’s likely due to your genes.In 95 percent of cases, balding is due to androgenetic alopecia, more commonly known as male pattern baldness, which is a hereditary condition. It can affect men of all ages, and may even start before the age of 21. Although you can’t prevent male pattern baldness, there are ways to slow down hair loss. Some options include medications such as Finasteride (Propecia, Proscar) and minoxidil (Rogaine, Ioniten), laser therapy, and hair transplant surgery. If you’re concerned about going bald, be sure to speak to your doctor or dermatologist. They can work with you to figure out the treatment options that are right for you. https://www.docsmart.in/ https://preview.redd.it/pk18px9onll91.png?width=576&format=png&auto=webp&s=64d1987e677a9e2598c1de7cacf1fae4bdb6314f |
2021.08.11 02:21 sammliane Unilateral flushing, eye tearing, pain and burning
This is a long history … sorry
31 F 5’5 190lbs - Dx 2002 (12yrs old) w/ GPA (Wegener’s Granulomatosis) w/ kidney (crescentic glomurerlonephritis), sinus, joint and skin manifestation. Currently stable with Rituxan infusions. Creatinine 98-110, last kidney biopsy in 2015 showed +50% glomeruli globally sclerosed with 10% moderately sclerosed. - Chronic migraine with aura - Sjogren’s - Possibly relapsing chondritis but Vasculitis dr not eager to change names - Psoriasis - Osteoporosis at 13yrs old with collapsed t6-7, currently osteopenia with premature degeneration of facet joint, neck kyphosis, SI joint dysfunction, osteoarthritis of all major joints w/ both hips operated in for labral tear and impingement. - Chronic pain - Unknown origin of recent peeing pure blood. Was on Cytoxan x2yrs, cystoscope and abdo u/s normal. Waiting for nephro. - 2017 ablation, dual av node, slow pathway removed - 3 pregnancies, 1 daughter (9yrs)
Meds - sertraline, Lipitor, Wellbutrin, Eltroxin (very new), propranolol (very new), oxyneo and oxycodone, plaquenil, Septra 3x/week, rituxan infusions, prednisone a couple times a year (20-30mg with quick taper), Flonase, Rupall, betahistine prn, axert prn, rizatriptan prn, zofran prn, and some that I know I’m forgetting. Recently came off topiramate (for migraine)
OK! So the issue is that for the past 4-5yrs I’ve gotten these weird “migraines” where only one side of my face flushes and feels like it’s burning. I’ll also get eye tearing/redness/slight droop on the same side as the flush. Today, the flushing and whatnot is on the left side with pain on the left as well, in temporal and ocular regions. Pain is abated momentarily with pressure under orbital bone near nose. Yesterday flushing, etc. was on right side with pain on left.
I’ve had weird symptoms for the past 6 yrs of chondritis where the upper part of ear will flush, burn and hurt. This happens everywhere I have a lot of cartilage (chest, nose bridge, knees and elbows). If you want pics I can send a link.
The “migraine” episodes flush the whole ear, cheek and lower part of forehead. I do not get the classic aura with these and they don’t respond well to anything.
Wtf is happening to me? They occur in groups and are just as debilitating, if not more so than my regular migraines. I’ve been getting them more and more. I came off of topiramate to try and regain some cognitive function 1-2 months ago but aphasia is worse now. No change in these episodes since discontinuing.
Bonus points if you can speak to the random bloody urine.
Also, please don’t tell me I need to come off of pain meds. I have a chronic pain doctor and I’m working on it, but currently I need them to be a mom that doesn’t spend all day in bed. Fuck Purdue.
Thanks so much for your time <3
Edit to add that ear fullness and mild fever also accompany the episodes, as do lower ab pain. 2nd edit - Sepsis 3yrs ago from PID (not caused by STI’s)
submitted by sammliane to AskDocs [link] [comments]
31 F 5’5 190lbs - Dx 2002 (12yrs old) w/ GPA (Wegener’s Granulomatosis) w/ kidney (crescentic glomurerlonephritis), sinus, joint and skin manifestation. Currently stable with Rituxan infusions. Creatinine 98-110, last kidney biopsy in 2015 showed +50% glomeruli globally sclerosed with 10% moderately sclerosed. - Chronic migraine with aura - Sjogren’s - Possibly relapsing chondritis but Vasculitis dr not eager to change names - Psoriasis - Osteoporosis at 13yrs old with collapsed t6-7, currently osteopenia with premature degeneration of facet joint, neck kyphosis, SI joint dysfunction, osteoarthritis of all major joints w/ both hips operated in for labral tear and impingement. - Chronic pain - Unknown origin of recent peeing pure blood. Was on Cytoxan x2yrs, cystoscope and abdo u/s normal. Waiting for nephro. - 2017 ablation, dual av node, slow pathway removed - 3 pregnancies, 1 daughter (9yrs)
Meds - sertraline, Lipitor, Wellbutrin, Eltroxin (very new), propranolol (very new), oxyneo and oxycodone, plaquenil, Septra 3x/week, rituxan infusions, prednisone a couple times a year (20-30mg with quick taper), Flonase, Rupall, betahistine prn, axert prn, rizatriptan prn, zofran prn, and some that I know I’m forgetting. Recently came off topiramate (for migraine)
OK! So the issue is that for the past 4-5yrs I’ve gotten these weird “migraines” where only one side of my face flushes and feels like it’s burning. I’ll also get eye tearing/redness/slight droop on the same side as the flush. Today, the flushing and whatnot is on the left side with pain on the left as well, in temporal and ocular regions. Pain is abated momentarily with pressure under orbital bone near nose. Yesterday flushing, etc. was on right side with pain on left.
I’ve had weird symptoms for the past 6 yrs of chondritis where the upper part of ear will flush, burn and hurt. This happens everywhere I have a lot of cartilage (chest, nose bridge, knees and elbows). If you want pics I can send a link.
The “migraine” episodes flush the whole ear, cheek and lower part of forehead. I do not get the classic aura with these and they don’t respond well to anything.
Wtf is happening to me? They occur in groups and are just as debilitating, if not more so than my regular migraines. I’ve been getting them more and more. I came off of topiramate to try and regain some cognitive function 1-2 months ago but aphasia is worse now. No change in these episodes since discontinuing.
Bonus points if you can speak to the random bloody urine.
Also, please don’t tell me I need to come off of pain meds. I have a chronic pain doctor and I’m working on it, but currently I need them to be a mom that doesn’t spend all day in bed. Fuck Purdue.
Thanks so much for your time <3
Edit to add that ear fullness and mild fever also accompany the episodes, as do lower ab pain. 2nd edit - Sepsis 3yrs ago from PID (not caused by STI’s)
2021.05.13 21:06 amothep8282 89 Year Old Woman With Recent Onset Dyspnea and No Bowel Movement in 15 Days
 | Chief Complaint: “She has been short of breath and not has a bowel movement in 15 days”. submitted by amothep8282 to ems [link] [comments] HPI: The patient experienced a fall 2 weeks prior from the current event, causing a humerus fracture. She was transported to the ER and underwent surgical repair of the fracture, spent 1 week in the hospital and was discharged home. She had a medical history of atrial fibrillation, anxiety, and hypercholesterolemia. Over the previous few days from this EMS encounter, the patient and family reported intermittent periods of shortness of breath. At the time of the 911 call, the patient was in moderate distress and tachypneic, and stated “it’s just too bad and I can’t catch my breath”. Assessment: On assessment she was conscious, alert, oriented, sitting reclined supine in an easy chair. Her respirations were tachypneic and shallow with evidence of discomfort on inspiration. Physical exam is noted below. The patient denied paroxysmal nocturnal dyspnea, orthopnea, and denied taking anticoagulants since her hospital discharge, which was instructed by the discharging physician. She was notably anxious, and extremely hesitant to be readmitted to the hospital. The family also reported the patient had not had a bowel movement in over 15 days. Her abdomen was noticeably enlarged with a slight fluid wave present. Physical Exam:
Behind the spoilers is a discussion of how we were completely blindsided by the final diagnosis. The final diagnosis was new onset heart failure with preserved ejection fraction (HFpEF), which is very different than heart failure with reduced ejection fraction (HFrEF). This would explain the new onset lower extremity edema and some rales in the posterior bases. Also, the neck of her gallbladder was impacted, likely causing the pain on inspiration. Lastly, >15 days with no bowel movement contributed to a bowel impaction which became necrotic, and she ultimately had a bowel resection. The 322 glucose we could not quite place at all, however, a pneumonia process would be consistent with trending towards an insulin resistant state because of inflammation, however, no fever was present. See this description below I wrote in a paper for how variables in cardiac output play together. It is also a fantastic example of how compensatory mechanisms can be engaged in shock, hypovolemia, etc via manipulation of these variables. Let’s examine cardiac output, which is heart rate x stroke volume. The stroke volume is also related to the ejection fraction in that stroke volume/end diastolic volume = the ejection fraction (%). Think about when the myocardium loses contractility in HFrEF – it cannot squeeze as hard and overcome the afterload and eject the same amount of blood as before, so more blood is left in the left ventricle and the ejection fraction goes down. Less overall blood leaves the ventricle so cardiac output goes down. Now in HFpEF, the issue is in FILLING, meaning the ventricle is stiffer and does not stretch as well to accommodate passive filling and atrial kick. So less blood enters the ventricle, and even though the ejection fraction is preserved, less overall blood in equals less blood out. If a person’s EF was 55% prior to HFpEF onset, let’s say they eject 50 ml of blood with each beat. After HFpEF onset, their EF remains the same at 55%, but they may only eject 35 ml of blood. Cardiac output therefore goes down. Ultimately, some process caused a new onset of HFpEF, which was exacerbated by an impaction of the gallbladder neck causing pain on inspiration. No bowel movement for 15 days could have caused a multitude of other issues as well. https://preview.redd.it/s2lqe9q6rxy61.png?width=691&format=png&auto=webp&s=f4f0c941a279141a291eafb0c62e32715dbba7a7 |
2021.04.07 23:22 jrt364 Can discontinuation of antipsychotics cause hyperthyroidism?
Not relevant, but 29M, 5'10", 118lbs
Meds: Haldol (haloperidol), Ritalin (methylphenidate), klonopin (clonazepam), cogentin (benztropine), Zoloft (sertraline), Lipitor (atorvastatin)
Can antipsychotic withdrawal cause low TSH (hyperthyroidism)? I stopped taking my antipsychotic (Haloperidol) about 5 weeks ago and a recent test indicated that I have a low TSH but normal T4. Medication wise, the discontinuation of Haloperidol is the only thing that has changed.
I am getting another TSH and T4 test in 4 weeks to see what is going on with my thyroid.
submitted by jrt364 to AskDocs [link] [comments]
Meds: Haldol (haloperidol), Ritalin (methylphenidate), klonopin (clonazepam), cogentin (benztropine), Zoloft (sertraline), Lipitor (atorvastatin)
Can antipsychotic withdrawal cause low TSH (hyperthyroidism)? I stopped taking my antipsychotic (Haloperidol) about 5 weeks ago and a recent test indicated that I have a low TSH but normal T4. Medication wise, the discontinuation of Haloperidol is the only thing that has changed.
I am getting another TSH and T4 test in 4 weeks to see what is going on with my thyroid.
2020.03.10 23:40 DadExplains List of 150 Pharmaceutical Drugs that may have shortages due to being sourced from China
Hey Gang. I've mentioned before that most drugs contain APIs (Active Pharmaceutical Ingredients) produced in China.
Also, here is a current list of Current and Resolved Drug Shortages and Discontinuations Reported to FDA. This list is actively updated by the FDA:
https://www.accessdata.fda.gov/scripts/drugshortages/default.cfm
If you rely on any of these medications, please talk to your Doctor and make sure you have enough to cover yourself for 60 days. Supply chains are starting to have issues. In a few weeks you may not be able to get your medication when you need it.
This is a list of 150 drugs that are sourced from China:
Aciclovir – (Zovirax) – antiviral drug
Advair – asthma medicine
Adrenaline Hcl – treatment for cardiac arrest
Albendazole – treatment for worms
Alfuzosin – (Uroxatral) treatment for enlarged prostate
Allopurinol – gout treatment
Alprazolam – (Xanax) – treatment for anxiety disorders
Amikacin sulfate – treatment for bacterial infections
Aminophyline -treatment for cerebral ischemia
Amiodarone Hydrochloride -treatment for irregular heartbeat
Amlodipine – treats high blood pressure & angina
Ampicillin – antibiotic
Amodiaquine – treatment of malaria
Amoxicillin – antibiotic
Aniracetam – (Draganon, Sarpul, Ampamet) a congnition enhancer
Artemether – treats drug resistant malaria
Artesunate – malaria treatment
Aspirin – anti-inflammatory painkiller
Artemether – treats malaria
Atenolol – high blood pressure medicine
Atropine – antidote against nerve agents
Avandia – (Avandia) treatment of diabetes
Budesonide – (Entocort) treatment of allergy & asthma
Bupropion (Wellbutrin) antidepressant
Calcifediol – treats vitamin D deficiency
Candesartan – (Blopress, Atacand, Amias, Ratacand) treats hypertension
Captopril – (Capoten, Inhibace) treatment for hypertension & congestive heart failure
Carbamazepine – treatment of epilepsy, ADD & ADHD
Carnosine – treatment for autism
Cefixime – antibiotic
Cefotaxime – (Claforan) antibiotic
Cefsulodin – also, cephalosporin – antibiotic
Cephealexin – (Keflex, Keftab) – antibiotic
Chloramphenicol – antibiotic
Chlorpheniramine Maleate – (Chlor-Trimeton, Piriton) Antihistamine
Chlorpromazine Hydrochloride
Chloroquine Phosphate – treatment of malaria
Cilexetil – (Atacand) treats high blood pressure
Cilostazole – (Pletal) treats peripheral vascular disease
Cimetidine – (Tagamet) – heartburn treatment
Ciprofloxacine – (Cipro) – antibiotic & one of two effective treatments for anthrax exposure
Clomiphene Citrate – (Clomid, Serophene, Milophene) infertility treatment
Clopidogrel Bisulfate – (Plavix) treats coronary artery disease
Co-trimoxazole – (Septrin, Bactrim) antibiotic
Cloxacillin – antibiotic
Coreg – (Coreg) beta blocker that treats congestive heart failure
Cromoglicate – treats allergies and asthma
Cyclosporine – immunosuppressive drug
Cytisine – (Tabex) smoking cessation drug
Dexamethasone Acetate – anti-inflammatory steroid
Diclofenac Sodium – (Flector patch/Voltaren) – anti-imflammatory painkiller used to treat arthritis, acute injury and menstrual pain
Diosmin – hemorrhoid treatment
Diphenhydramine hydrochloride – (Benadryl) antihistimine
Doxycycline Hcl – (Vibramycin) – antibiotic
Enalapril – (Renitec, Vasotec) treatment of hypertension, chronic heart failure
Enoxacin – (Enroxil, Penetrex) antibiotic
Erythromycin – antibiotic
Famotidine – (Pepcid) antacid
Ferrous Sulfate – treatment for iron-deficiency anemia
Flucloxacillin – (Flopen, Floxapen) antibiotic
Fluconazole – (Diflucan, Trican) antifungal drug
Furosemide – (Lasix) diuretic for treating congestive heart failure
Frusemide – diuretic used to treat heart failure & edema
Flucloxacillin sodium – antibiotic
Gentamycin – antibiotic
Glibenclamide (Diabeta, Flynase, Micronase) anti-diabetic drug
Gliclazide – diabetes treatment
Griseofulvin – antifungal drug
Glyceryl Trinitrate – treatment of angina & heart disease
Hydrochlorothiazide – (Aquazide H, Dichlotride, Microzide, Oretic) diuretic
Human growth hormone – treatment of growth failure in children
Ibuprofen – anti-inflammatory painkiller
Imitrex – (Imatrex) migraine medicine
Indomethazine – anti-inflammatory painkiller
Ketoconazole – (Nizoral) antifungal drug
Lincomycine – antibiotic
Lamictal – treatment for epilepsy & bipolar disorder
Letrozole – treatment of breast cancerLipitor – (Lipitor) lowers cholesteral
Loratadine (Claritin, Lomilan, Clarinase, Alavert, AllergyX) antihistamine
Lovastatin- lowers cholesteral
Lumefantrine – treatment of malaria
Mebendazole – (Ovex, Vermox, Antiox, Pripsen) treatment for worms
Mefenamic Acid – (Ponstel, Ponstan) non-steroidal, anti-inflammatory painkiller
Meloxicam – (Mobic) non-steroidal, anti-inflammatory painkiller
Metamizole sodium (Analgin, Dipyrone, Novalgin) painkiller, fever-reducer
Methyldopa – (Aldomet, Dopamet, Novomedopa) antihypertension drug
Metoclopramide – (Maxolon, Reglan, Degan, Maxeran, Primeran) anti-nausea drug
Metronidazole – treats infections
Moexipril – (Univasc) treatment of high blood pressure
Mycophenolate Mofetil – Immunosuppressive drug
Niclosamide – treats tapeworms
Nifedipine (Adalat, Nifedical, Procardia) treats hypertension, premature labor
Nitroglycerin – (Nitrospan, Nitrostat, Tridil) heart medication
Norfloxacin – antibiotic
Ofloxacin – (Floxin) antibiotic
Ondansetron – (Zofran) – nausea prevention for chemo patients
Orlistat – (Xenical) – obesity treatment
Oxandrolone – Synthetic anabolic steroid
Oxybutinin – treatment for incontinence
Oxymetholone – Synthetic anabolic steroid
Oxytetracycline – antibiotic
Paclitaxel – also taxol – cancer treatment
Paracetamol – also, acetaminophen – painkiller
Penicillin – antibiotic
Phenacetin – painkiller
Phenformin Hydrochloride – diabetes treatment
Prednisone – steroid
Promethazine Hydrochloride – (Phenergan, Romergan, Fargan, Avomine) antihistamine
Propranolol – (Inderal, Avlocardyl, Dociton, Inderalici, InnoPran XL) hypertension treatment
Pyrimethamine – (Daraprim) antimalarial drug
Propecia – (Propecia) for prostate enlargement and hair loss
Quinine – malaria treatment
Ramipril – used to treat hypertension and congestive heart failure
Ranitidine Hydrochloride – (Zantac) antacid
Ribavirin – (Copegus, Rebetol, Ribashere, Vilona, Virazole) anti-viral drug
Rifampicin+Isoniazid – malaria treatment
Ribavirin – (Copegus, Rebetol, Ribashere) antivirual drug
Rifampicin – antibiotic
Salbutamol – asthma, copd
Sibutramine – (Meridia) obesity treatment
Spironolactone – (Aldactone, Novo-Spiroton, Verospiron, Berlactone) diuretic
Streptomycin – antibiotic
Sucralfate – (Carafate) – treats ulcers & acid reflux disease
Sulfadiazine – antibiotic
Sulfamethoxazole – antibiotic
Sulfadoxine&Pyrimethamine – treatment for malaria
Sulpiride – (Meresa, Sulpirid Ratiopharm) treatment of schizophrenia
Tamoxifen – breast cancer treatment
Tinidazole – (Tindamax, Fasigyn) anti-parasitic drug
Trandolapril – treatment of high blood pressure
Trimethoprim – antibiotic
Valaciclovir – (Valtrex) antiviral drug
submitted by DadExplains to PandemicPreps [link] [comments]
Also, here is a current list of Current and Resolved Drug Shortages and Discontinuations Reported to FDA. This list is actively updated by the FDA:
https://www.accessdata.fda.gov/scripts/drugshortages/default.cfm
If you rely on any of these medications, please talk to your Doctor and make sure you have enough to cover yourself for 60 days. Supply chains are starting to have issues. In a few weeks you may not be able to get your medication when you need it.
This is a list of 150 drugs that are sourced from China:
Aciclovir – (Zovirax) – antiviral drug
Advair – asthma medicine
Adrenaline Hcl – treatment for cardiac arrest
Albendazole – treatment for worms
Alfuzosin – (Uroxatral) treatment for enlarged prostate
Allopurinol – gout treatment
Alprazolam – (Xanax) – treatment for anxiety disorders
Amikacin sulfate – treatment for bacterial infections
Aminophyline -treatment for cerebral ischemia
Amiodarone Hydrochloride -treatment for irregular heartbeat
Amlodipine – treats high blood pressure & angina
Ampicillin – antibiotic
Amodiaquine – treatment of malaria
Amoxicillin – antibiotic
Aniracetam – (Draganon, Sarpul, Ampamet) a congnition enhancer
Artemether – treats drug resistant malaria
Artesunate – malaria treatment
Aspirin – anti-inflammatory painkiller
Artemether – treats malaria
Atenolol – high blood pressure medicine
Atropine – antidote against nerve agents
Avandia – (Avandia) treatment of diabetes
Budesonide – (Entocort) treatment of allergy & asthma
Bupropion (Wellbutrin) antidepressant
Calcifediol – treats vitamin D deficiency
Candesartan – (Blopress, Atacand, Amias, Ratacand) treats hypertension
Captopril – (Capoten, Inhibace) treatment for hypertension & congestive heart failure
Carbamazepine – treatment of epilepsy, ADD & ADHD
Carnosine – treatment for autism
Cefixime – antibiotic
Cefotaxime – (Claforan) antibiotic
Cefsulodin – also, cephalosporin – antibiotic
Cephealexin – (Keflex, Keftab) – antibiotic
Chloramphenicol – antibiotic
Chlorpheniramine Maleate – (Chlor-Trimeton, Piriton) Antihistamine
Chlorpromazine Hydrochloride
Chloroquine Phosphate – treatment of malaria
Cilexetil – (Atacand) treats high blood pressure
Cilostazole – (Pletal) treats peripheral vascular disease
Cimetidine – (Tagamet) – heartburn treatment
Ciprofloxacine – (Cipro) – antibiotic & one of two effective treatments for anthrax exposure
Clomiphene Citrate – (Clomid, Serophene, Milophene) infertility treatment
Clopidogrel Bisulfate – (Plavix) treats coronary artery disease
Co-trimoxazole – (Septrin, Bactrim) antibiotic
Cloxacillin – antibiotic
Coreg – (Coreg) beta blocker that treats congestive heart failure
Cromoglicate – treats allergies and asthma
Cyclosporine – immunosuppressive drug
Cytisine – (Tabex) smoking cessation drug
Dexamethasone Acetate – anti-inflammatory steroid
Diclofenac Sodium – (Flector patch/Voltaren) – anti-imflammatory painkiller used to treat arthritis, acute injury and menstrual pain
Diosmin – hemorrhoid treatment
Diphenhydramine hydrochloride – (Benadryl) antihistimine
Doxycycline Hcl – (Vibramycin) – antibiotic
Enalapril – (Renitec, Vasotec) treatment of hypertension, chronic heart failure
Enoxacin – (Enroxil, Penetrex) antibiotic
Erythromycin – antibiotic
Famotidine – (Pepcid) antacid
Ferrous Sulfate – treatment for iron-deficiency anemia
Flucloxacillin – (Flopen, Floxapen) antibiotic
Fluconazole – (Diflucan, Trican) antifungal drug
Furosemide – (Lasix) diuretic for treating congestive heart failure
Frusemide – diuretic used to treat heart failure & edema
Flucloxacillin sodium – antibiotic
Gentamycin – antibiotic
Glibenclamide (Diabeta, Flynase, Micronase) anti-diabetic drug
Gliclazide – diabetes treatment
Griseofulvin – antifungal drug
Glyceryl Trinitrate – treatment of angina & heart disease
Hydrochlorothiazide – (Aquazide H, Dichlotride, Microzide, Oretic) diuretic
Human growth hormone – treatment of growth failure in children
Ibuprofen – anti-inflammatory painkiller
Imitrex – (Imatrex) migraine medicine
Indomethazine – anti-inflammatory painkiller
Ketoconazole – (Nizoral) antifungal drug
Lincomycine – antibiotic
Lamictal – treatment for epilepsy & bipolar disorder
Letrozole – treatment of breast cancerLipitor – (Lipitor) lowers cholesteral
Loratadine (Claritin, Lomilan, Clarinase, Alavert, AllergyX) antihistamine
Lovastatin- lowers cholesteral
Lumefantrine – treatment of malaria
Mebendazole – (Ovex, Vermox, Antiox, Pripsen) treatment for worms
Mefenamic Acid – (Ponstel, Ponstan) non-steroidal, anti-inflammatory painkiller
Meloxicam – (Mobic) non-steroidal, anti-inflammatory painkiller
Metamizole sodium (Analgin, Dipyrone, Novalgin) painkiller, fever-reducer
Methyldopa – (Aldomet, Dopamet, Novomedopa) antihypertension drug
Metoclopramide – (Maxolon, Reglan, Degan, Maxeran, Primeran) anti-nausea drug
Metronidazole – treats infections
Moexipril – (Univasc) treatment of high blood pressure
Mycophenolate Mofetil – Immunosuppressive drug
Niclosamide – treats tapeworms
Nifedipine (Adalat, Nifedical, Procardia) treats hypertension, premature labor
Nitroglycerin – (Nitrospan, Nitrostat, Tridil) heart medication
Norfloxacin – antibiotic
Ofloxacin – (Floxin) antibiotic
Ondansetron – (Zofran) – nausea prevention for chemo patients
Orlistat – (Xenical) – obesity treatment
Oxandrolone – Synthetic anabolic steroid
Oxybutinin – treatment for incontinence
Oxymetholone – Synthetic anabolic steroid
Oxytetracycline – antibiotic
Paclitaxel – also taxol – cancer treatment
Paracetamol – also, acetaminophen – painkiller
Penicillin – antibiotic
Phenacetin – painkiller
Phenformin Hydrochloride – diabetes treatment
Prednisone – steroid
Promethazine Hydrochloride – (Phenergan, Romergan, Fargan, Avomine) antihistamine
Propranolol – (Inderal, Avlocardyl, Dociton, Inderalici, InnoPran XL) hypertension treatment
Pyrimethamine – (Daraprim) antimalarial drug
Propecia – (Propecia) for prostate enlargement and hair loss
Quinine – malaria treatment
Ramipril – used to treat hypertension and congestive heart failure
Ranitidine Hydrochloride – (Zantac) antacid
Ribavirin – (Copegus, Rebetol, Ribashere, Vilona, Virazole) anti-viral drug
Rifampicin+Isoniazid – malaria treatment
Ribavirin – (Copegus, Rebetol, Ribashere) antivirual drug
Rifampicin – antibiotic
Salbutamol – asthma, copd
Sibutramine – (Meridia) obesity treatment
Spironolactone – (Aldactone, Novo-Spiroton, Verospiron, Berlactone) diuretic
Streptomycin – antibiotic
Sucralfate – (Carafate) – treats ulcers & acid reflux disease
Sulfadiazine – antibiotic
Sulfamethoxazole – antibiotic
Sulfadoxine&Pyrimethamine – treatment for malaria
Sulpiride – (Meresa, Sulpirid Ratiopharm) treatment of schizophrenia
Tamoxifen – breast cancer treatment
Tinidazole – (Tindamax, Fasigyn) anti-parasitic drug
Trandolapril – treatment of high blood pressure
Trimethoprim – antibiotic
Valaciclovir – (Valtrex) antiviral drug
2019.11.21 20:18 TenMilePt Family history of high cholesterol, negative reaction to statins
Hey all,
Seeking input here. I am a male, early 50's and have a history of high cholesterol. In fact, it runs in my family with my 3 brothers also diagnosed, along with my father. There is also a family history of heart disease and interestingly enough, I had a recent DNA test and got myself a Promthease report done also showing a level 4 magnitude of cornary artery disease (2-3x likelihood of developing the disease). Given all that risk, my doctor had me in for a cornary CT scan which is showing some early signs of plaque build up in my arteries.
In the past, the doctor has put me on statins -- both Lipitor and Crestor but I have found that they caused me terrible muscle pain in all of my joints. The statins were very effective at their jobs and my cholesterol numbers quickly fell into the normal ranges. However, the joint pain wasn't something that I was willing to live with so I discontinued the medications. Unfortunately, within the past year, my older brother died of a heart attack, so I figure I'd better get back to lowering my cholesterol.
I should add that I am very active and cycle roughly 200+ times per year and put over 5000kms on my bike. I don't smoke, not a heavy drinker and my diet is generally healthy (not a ton of red meat, lots of fish and veggies) -- yet without medication, my cholesterol is high. My doctor sent me to the Lipid Clinic and at the end of Sept I was put back on a low dose combination of Rosuvastatin (5mg every other day) and Ezetimibe (10mg daily). These drugs have done their job -- got my results back yesterday and total cholesterol has gone from 6.04 to 4.12 , HDL from 0.82 to 1.02 and CHOL/HDL (risk ratio) from 7.37 to 4.04 in roughly 6 weeks time (everything normal).
Unfortunately however, the side-effects are back. I have terrible joint pain and stiffness -- particularly in my legs/hips and I feel tired all the time, with sort of a fuzzy mental state. When I do cycle, I am constantly fatigued and barely able to keep up to friends who normally have touble keeping up with me. When I finish exercise, often I have to take a 60-90 minute nap as I am completely drained. Given my history of side-effects with statins, the Lipid Clinic also ordered a test of muscle enzymes which show a CK level of 336 (which is about double what they should be -- target is <165) -- unfortunately I don't have a baseline showing any change as this test had not been done earlier. Apparently an increase CK level with muscle pain can be a side effect of statins and it seems to be the case in my situation.
Anyhow, given the side-effects, I am stopping the statins and have made an appointment with my GP. The Lipid Clinic has mentioned that if the statins do cause side effects, there may be an injection option that can be very expensive -- but may be covered under my health plan if we can show the negative effect of statins -- which we obviously can. I can't get back to see them for a few months however.
Any thoughts on my plan of action? I understand that taking co-enzyme Q10 can help reduce some of the joint pain, and certainly won't hurt. Any other recommendations from those more experienced in getting things under control?
submitted by TenMilePt to Cholesterol [link] [comments]
Seeking input here. I am a male, early 50's and have a history of high cholesterol. In fact, it runs in my family with my 3 brothers also diagnosed, along with my father. There is also a family history of heart disease and interestingly enough, I had a recent DNA test and got myself a Promthease report done also showing a level 4 magnitude of cornary artery disease (2-3x likelihood of developing the disease). Given all that risk, my doctor had me in for a cornary CT scan which is showing some early signs of plaque build up in my arteries.
In the past, the doctor has put me on statins -- both Lipitor and Crestor but I have found that they caused me terrible muscle pain in all of my joints. The statins were very effective at their jobs and my cholesterol numbers quickly fell into the normal ranges. However, the joint pain wasn't something that I was willing to live with so I discontinued the medications. Unfortunately, within the past year, my older brother died of a heart attack, so I figure I'd better get back to lowering my cholesterol.
I should add that I am very active and cycle roughly 200+ times per year and put over 5000kms on my bike. I don't smoke, not a heavy drinker and my diet is generally healthy (not a ton of red meat, lots of fish and veggies) -- yet without medication, my cholesterol is high. My doctor sent me to the Lipid Clinic and at the end of Sept I was put back on a low dose combination of Rosuvastatin (5mg every other day) and Ezetimibe (10mg daily). These drugs have done their job -- got my results back yesterday and total cholesterol has gone from 6.04 to 4.12 , HDL from 0.82 to 1.02 and CHOL/HDL (risk ratio) from 7.37 to 4.04 in roughly 6 weeks time (everything normal).
Unfortunately however, the side-effects are back. I have terrible joint pain and stiffness -- particularly in my legs/hips and I feel tired all the time, with sort of a fuzzy mental state. When I do cycle, I am constantly fatigued and barely able to keep up to friends who normally have touble keeping up with me. When I finish exercise, often I have to take a 60-90 minute nap as I am completely drained. Given my history of side-effects with statins, the Lipid Clinic also ordered a test of muscle enzymes which show a CK level of 336 (which is about double what they should be -- target is <165) -- unfortunately I don't have a baseline showing any change as this test had not been done earlier. Apparently an increase CK level with muscle pain can be a side effect of statins and it seems to be the case in my situation.
Anyhow, given the side-effects, I am stopping the statins and have made an appointment with my GP. The Lipid Clinic has mentioned that if the statins do cause side effects, there may be an injection option that can be very expensive -- but may be covered under my health plan if we can show the negative effect of statins -- which we obviously can. I can't get back to see them for a few months however.
Any thoughts on my plan of action? I understand that taking co-enzyme Q10 can help reduce some of the joint pain, and certainly won't hurt. Any other recommendations from those more experienced in getting things under control?
2019.07.11 01:04 PrestigiousProof An MD's reply to a Big Pharma Smear
An article (jamacardiology_navar_2019_vp_190009) in the June, 2019 edition of JAMA Cardiology was titled, “Fear-Based Medical Misinformation and Disease Prevention: From Vaccines to Statins. In this article,[i] the author states “fake medical news” as the reason that patients are exhibiting hesitancy about utilizing statins and vaccines.
The author correctly points out that in 1963, before the measles, mumps and rubella vaccine was licensed, there were 3-4 million people who contracted measles each year. The immunization campaign which utilizes the MMR vaccine has decreased the incidence of measles. The author blames vaccine refusers for fueling outbreaks of measles. Yes, the recent outbreak in measles has been primarily in the unvaccinated population. However, mandating that every child receive the MMR does not guarantee a measles-free population. China continues to have measles outbreaks even though Chinese children are the most vaccinated in the world—over 99% of Chinese children are fully vaccinated for measles.[ii] Furthermore, there has been a rash of mumps outbreaks across the US since 2006–all in fully vaccinated populations.[iii] In 2015-2016, 453 cases of mumps were recorded with 98% being fully vaccinated. In fact, from 2016-2017, there have been over 9,200 cases of mumps in the US, mostly from fully vaccinated people.
The author claims that “…pediatricians and public health officials have been battling fake news about vaccine safety.” US children are the most vaccinated in the world. US children have the most chronic disease when compared to other Western children. In fact, over half of US children suffer with a chronic disease.[iv] Chronic disease in children has been increasing at epidemic rates at the same time we have been rapidly expanding the US childhood vaccine schedule. Since when is it fake news to question whether the expanding vaccine schedule correlates with the increasing rates of childhood illnesses?!
The author claims that “…the same fake medical news and fearmongering also plague the cardiovascular world through relentless attacks on statins.” The author further states that a popular health website[v] “…incorrectly indicates that statins cause memory loss, cataracts, pancreatic dysfunction, Lou Gehrig disease, and cancer. Many of these sites criticize statin researchers for links to ‘big pharma’…”
The Physicians Desk Reference states that adverse reactions associated with Lipitor include the cognitive impairment (memory loss, forgetfulness, amnesia, memory impairment, and confusion associated with stain use). Furthermore post-marketing studies have found Lipitor use associated with pancreatitis.[vi] Other researchers have reported a relationship between statin use and Lou Gehrig’s disease.[vii] Finally, peer-reviewed research has reported a relationship between statin use and cataracts.[viii] Statins being associated with serious adverse effects has nothing to do with fake news. These are facts.
As for criticizing researchers for links to “big pharma” I would like to ask why is that a bad thing? Researchers studying the association between the presence of individual principal investigators’ financial ties to the manufacturer of the drug study and the trial’s outcomes have shown that financial ties of principal investigators were independently associated with positive clinical trial results.[ix] So, perhaps it is not fake news to point out that doctors should question the independence of every author and they should look critically at anyone who has financial ties to industry.
The author claims that “With the exception of a small, vocal minority, most physicians believe that statins, as with vaccines, are safe and effective.” Just because the majority of physicians believe something does not make it true. Vioxx was marketed to physicians as safer than older NSAIDs. This was ‘believed’ by a majority of physicians. The result of this belief was over 60,000 deaths and 140,000 heart attacks. Vioxx was eventually pulled from the marketplace due to the serious events it caused.
The author blames fake news because patients are concerned about statin safety. A large percentage of patients stop statin drugs due to side effects.[x] I find it doubtful that fake news is responsible for a large percentage of patients to suffer adverse effects from statin therapy. I have been a clinician for over 25 years and regularly heard patients complaining about statin adverse effects.
The author states that transparency and clear communication to patients is critical to maintain trust. I could not agree more. Perhaps the US Centers for Disease Control and Prevention can allow a senior CDC scientist William Thompson—who has claimed whistleblower protection–to testify about his claims that the CDC lied, hid, and altered data that showed the MMR vaccine when given before 36 months of age is associated with autism. The CDC has refused to allow Dr. Thompson to testify about his claims. Dr. Thompson has claimed whistleblower status. And, perhaps the CDC can comment on another Federal case where the mumps part of the MMR is in court because two Merck whistleblowers have come forward stating the Merck falsified the data on the efficacy of the mumps part of the MMR vaccine.
The JAMA author states that the medical community needs to stay vigilant. Again, I could not agree more. Vigilance with Vioxx would have saved tens of thousands of lives and prevented hundreds of thousands of heart attacks.
Questioning the wisdom, safety and efficacy of any therapy is not fake news. It is what physicians should be doing.
My friend and colleague, David Diamond, Ph.D, also took exception to the JAMA Cardiology article. We wrote (Dr. Diamond was the principal author on this reply) the following reply which was rejected by the JAMA Cardiology. Refer to the link below to read our letter to JAMA: submitted_version
[i] https://jamanetwork.com/journals/jamacardiology/article-abstract/2736328
[ii] PLOS One. 2014; 9(2): e89631
[iii] Accessed 6.28.19 from: https://www.cdc.gov/mumps/outbreaks.html
[iv] American Pediatrics. Vol. 11. Issue 3, Supplement May – June 2011. S22-S33
[v] How much do you really know about vaccine safety? https://articles.mercola.com/sites/articles/ archive/2017/12/16/how-much-do-you-knowabout-vaccine-safety.aspx.AccessedMarch27, 2019.
[vi] Accessed 6.28.19 from: http://labeling.pfizer.com/ShowLabeling.aspx?id=587#section-5
[vii] Drug Saf (2018) 41:403–413 https://doi.org/10.1007/s40264-017-0620-4
[viii] 1040-5488/12/8908-1165/0 VOL. 89, NO. 8, PP. 1165–1171 OPTOMETRY AND VISION SCIENCE
[ix] the bmj BMJ 2017;356:i6770 doi: 10.1136/bmj.i6770
[x] Annals of Int. Med. April 2, 2013. https://annals.org/aim/article-abstract/1671715/discontinuation-statins-routine-care-settings-cohort-study https://www.drbrownstein.com/from-vaccines-to-statins-a-reply-to-fake-news-in-jama-cardiology/
submitted by PrestigiousProof to C_S_T [link] [comments]
The author correctly points out that in 1963, before the measles, mumps and rubella vaccine was licensed, there were 3-4 million people who contracted measles each year. The immunization campaign which utilizes the MMR vaccine has decreased the incidence of measles. The author blames vaccine refusers for fueling outbreaks of measles. Yes, the recent outbreak in measles has been primarily in the unvaccinated population. However, mandating that every child receive the MMR does not guarantee a measles-free population. China continues to have measles outbreaks even though Chinese children are the most vaccinated in the world—over 99% of Chinese children are fully vaccinated for measles.[ii] Furthermore, there has been a rash of mumps outbreaks across the US since 2006–all in fully vaccinated populations.[iii] In 2015-2016, 453 cases of mumps were recorded with 98% being fully vaccinated. In fact, from 2016-2017, there have been over 9,200 cases of mumps in the US, mostly from fully vaccinated people.
The author claims that “…pediatricians and public health officials have been battling fake news about vaccine safety.” US children are the most vaccinated in the world. US children have the most chronic disease when compared to other Western children. In fact, over half of US children suffer with a chronic disease.[iv] Chronic disease in children has been increasing at epidemic rates at the same time we have been rapidly expanding the US childhood vaccine schedule. Since when is it fake news to question whether the expanding vaccine schedule correlates with the increasing rates of childhood illnesses?!
The author claims that “…the same fake medical news and fearmongering also plague the cardiovascular world through relentless attacks on statins.” The author further states that a popular health website[v] “…incorrectly indicates that statins cause memory loss, cataracts, pancreatic dysfunction, Lou Gehrig disease, and cancer. Many of these sites criticize statin researchers for links to ‘big pharma’…”
The Physicians Desk Reference states that adverse reactions associated with Lipitor include the cognitive impairment (memory loss, forgetfulness, amnesia, memory impairment, and confusion associated with stain use). Furthermore post-marketing studies have found Lipitor use associated with pancreatitis.[vi] Other researchers have reported a relationship between statin use and Lou Gehrig’s disease.[vii] Finally, peer-reviewed research has reported a relationship between statin use and cataracts.[viii] Statins being associated with serious adverse effects has nothing to do with fake news. These are facts.
As for criticizing researchers for links to “big pharma” I would like to ask why is that a bad thing? Researchers studying the association between the presence of individual principal investigators’ financial ties to the manufacturer of the drug study and the trial’s outcomes have shown that financial ties of principal investigators were independently associated with positive clinical trial results.[ix] So, perhaps it is not fake news to point out that doctors should question the independence of every author and they should look critically at anyone who has financial ties to industry.
The author claims that “With the exception of a small, vocal minority, most physicians believe that statins, as with vaccines, are safe and effective.” Just because the majority of physicians believe something does not make it true. Vioxx was marketed to physicians as safer than older NSAIDs. This was ‘believed’ by a majority of physicians. The result of this belief was over 60,000 deaths and 140,000 heart attacks. Vioxx was eventually pulled from the marketplace due to the serious events it caused.
The author blames fake news because patients are concerned about statin safety. A large percentage of patients stop statin drugs due to side effects.[x] I find it doubtful that fake news is responsible for a large percentage of patients to suffer adverse effects from statin therapy. I have been a clinician for over 25 years and regularly heard patients complaining about statin adverse effects.
The author states that transparency and clear communication to patients is critical to maintain trust. I could not agree more. Perhaps the US Centers for Disease Control and Prevention can allow a senior CDC scientist William Thompson—who has claimed whistleblower protection–to testify about his claims that the CDC lied, hid, and altered data that showed the MMR vaccine when given before 36 months of age is associated with autism. The CDC has refused to allow Dr. Thompson to testify about his claims. Dr. Thompson has claimed whistleblower status. And, perhaps the CDC can comment on another Federal case where the mumps part of the MMR is in court because two Merck whistleblowers have come forward stating the Merck falsified the data on the efficacy of the mumps part of the MMR vaccine.
The JAMA author states that the medical community needs to stay vigilant. Again, I could not agree more. Vigilance with Vioxx would have saved tens of thousands of lives and prevented hundreds of thousands of heart attacks.
Questioning the wisdom, safety and efficacy of any therapy is not fake news. It is what physicians should be doing.
My friend and colleague, David Diamond, Ph.D, also took exception to the JAMA Cardiology article. We wrote (Dr. Diamond was the principal author on this reply) the following reply which was rejected by the JAMA Cardiology. Refer to the link below to read our letter to JAMA: submitted_version
[i] https://jamanetwork.com/journals/jamacardiology/article-abstract/2736328
[ii] PLOS One. 2014; 9(2): e89631
[iii] Accessed 6.28.19 from: https://www.cdc.gov/mumps/outbreaks.html
[iv] American Pediatrics. Vol. 11. Issue 3, Supplement May – June 2011. S22-S33
[v] How much do you really know about vaccine safety? https://articles.mercola.com/sites/articles/ archive/2017/12/16/how-much-do-you-knowabout-vaccine-safety.aspx.AccessedMarch27, 2019.
[vi] Accessed 6.28.19 from: http://labeling.pfizer.com/ShowLabeling.aspx?id=587#section-5
[vii] Drug Saf (2018) 41:403–413 https://doi.org/10.1007/s40264-017-0620-4
[viii] 1040-5488/12/8908-1165/0 VOL. 89, NO. 8, PP. 1165–1171 OPTOMETRY AND VISION SCIENCE
[ix] the bmj BMJ 2017;356:i6770 doi: 10.1136/bmj.i6770
[x] Annals of Int. Med. April 2, 2013. https://annals.org/aim/article-abstract/1671715/discontinuation-statins-routine-care-settings-cohort-study https://www.drbrownstein.com/from-vaccines-to-statins-a-reply-to-fake-news-in-jama-cardiology/
2019.07.11 01:04 PrestigiousProof An MD''s reply to a Big Pharma Smear
An article (jamacardiology_navar_2019_vp_190009) in the June, 2019 edition of JAMA Cardiology was titled, “Fear-Based Medical Misinformation and Disease Prevention: From Vaccines to Statins. In this article,[i] the author states “fake medical news” as the reason that patients are exhibiting hesitancy about utilizing statins and vaccines.
The author correctly points out that in 1963, before the measles, mumps and rubella vaccine was licensed, there were 3-4 million people who contracted measles each year. The immunization campaign which utilizes the MMR vaccine has decreased the incidence of measles. The author blames vaccine refusers for fueling outbreaks of measles. Yes, the recent outbreak in measles has been primarily in the unvaccinated population. However, mandating that every child receive the MMR does not guarantee a measles-free population. China continues to have measles outbreaks even though Chinese children are the most vaccinated in the world—over 99% of Chinese children are fully vaccinated for measles.[ii] Furthermore, there has been a rash of mumps outbreaks across the US since 2006–all in fully vaccinated populations.[iii] In 2015-2016, 453 cases of mumps were recorded with 98% being fully vaccinated. In fact, from 2016-2017, there have been over 9,200 cases of mumps in the US, mostly from fully vaccinated people.
The author claims that “…pediatricians and public health officials have been battling fake news about vaccine safety.” US children are the most vaccinated in the world. US children have the most chronic disease when compared to other Western children. In fact, over half of US children suffer with a chronic disease.[iv] Chronic disease in children has been increasing at epidemic rates at the same time we have been rapidly expanding the US childhood vaccine schedule. Since when is it fake news to question whether the expanding vaccine schedule correlates with the increasing rates of childhood illnesses?!
The author claims that “…the same fake medical news and fearmongering also plague the cardiovascular world through relentless attacks on statins.” The author further states that a popular health website[v] “…incorrectly indicates that statins cause memory loss, cataracts, pancreatic dysfunction, Lou Gehrig disease, and cancer. Many of these sites criticize statin researchers for links to ‘big pharma’…”
The Physicians Desk Reference states that adverse reactions associated with Lipitor include the cognitive impairment (memory loss, forgetfulness, amnesia, memory impairment, and confusion associated with stain use). Furthermore post-marketing studies have found Lipitor use associated with pancreatitis.[vi] Other researchers have reported a relationship between statin use and Lou Gehrig’s disease.[vii] Finally, peer-reviewed research has reported a relationship between statin use and cataracts.[viii] Statins being associated with serious adverse effects has nothing to do with fake news. These are facts.
As for criticizing researchers for links to “big pharma” I would like to ask why is that a bad thing? Researchers studying the association between the presence of individual principal investigators’ financial ties to the manufacturer of the drug study and the trial’s outcomes have shown that financial ties of principal investigators were independently associated with positive clinical trial results.[ix] So, perhaps it is not fake news to point out that doctors should question the independence of every author and they should look critically at anyone who has financial ties to industry.
The author claims that “With the exception of a small, vocal minority, most physicians believe that statins, as with vaccines, are safe and effective.” Just because the majority of physicians believe something does not make it true. Vioxx was marketed to physicians as safer than older NSAIDs. This was ‘believed’ by a majority of physicians. The result of this belief was over 60,000 deaths and 140,000 heart attacks. Vioxx was eventually pulled from the marketplace due to the serious events it caused.
The author blames fake news because patients are concerned about statin safety. A large percentage of patients stop statin drugs due to side effects.[x] I find it doubtful that fake news is responsible for a large percentage of patients to suffer adverse effects from statin therapy. I have been a clinician for over 25 years and regularly heard patients complaining about statin adverse effects.
The author states that transparency and clear communication to patients is critical to maintain trust. I could not agree more. Perhaps the US Centers for Disease Control and Prevention can allow a senior CDC scientist William Thompson—who has claimed whistleblower protection–to testify about his claims that the CDC lied, hid, and altered data that showed the MMR vaccine when given before 36 months of age is associated with autism. The CDC has refused to allow Dr. Thompson to testify about his claims. Dr. Thompson has claimed whistleblower status. And, perhaps the CDC can comment on another Federal case where the mumps part of the MMR is in court because two Merck whistleblowers have come forward stating the Merck falsified the data on the efficacy of the mumps part of the MMR vaccine.
The JAMA author states that the medical community needs to stay vigilant. Again, I could not agree more. Vigilance with Vioxx would have saved tens of thousands of lives and prevented hundreds of thousands of heart attacks.
Questioning the wisdom, safety and efficacy of any therapy is not fake news. It is what physicians should be doing.
My friend and colleague, David Diamond, Ph.D, also took exception to the JAMA Cardiology article. We wrote (Dr. Diamond was the principal author on this reply) the following reply which was rejected by the JAMA Cardiology. Refer to the link below to read our letter to JAMA: submitted_version
[i] https://jamanetwork.com/journals/jamacardiology/article-abstract/2736328
[ii] PLOS One. 2014; 9(2): e89631
[iii] Accessed 6.28.19 from: https://www.cdc.gov/mumps/outbreaks.html
[iv] American Pediatrics. Vol. 11. Issue 3, Supplement May – June 2011. S22-S33
[v] How much do you really know about vaccine safety? https://articles.mercola.com/sites/articles/ archive/2017/12/16/how-much-do-you-knowabout-vaccine-safety.aspx.AccessedMarch27, 2019.
[vi] Accessed 6.28.19 from: http://labeling.pfizer.com/ShowLabeling.aspx?id=587#section-5
[vii] Drug Saf (2018) 41:403–413 https://doi.org/10.1007/s40264-017-0620-4
[viii] 1040-5488/12/8908-1165/0 VOL. 89, NO. 8, PP. 1165–1171 OPTOMETRY AND VISION SCIENCE
[ix] the bmj BMJ 2017;356:i6770 doi: 10.1136/bmj.i6770
[x] Annals of Int. Med. April 2, 2013. https://annals.org/aim/article-abstract/1671715/discontinuation-statins-routine-care-settings-cohort-study https://www.drbrownstein.com/from-vaccines-to-statins-a-reply-to-fake-news-in-jama-cardiology/
submitted by PrestigiousProof to conspiracyundone [link] [comments]
The author correctly points out that in 1963, before the measles, mumps and rubella vaccine was licensed, there were 3-4 million people who contracted measles each year. The immunization campaign which utilizes the MMR vaccine has decreased the incidence of measles. The author blames vaccine refusers for fueling outbreaks of measles. Yes, the recent outbreak in measles has been primarily in the unvaccinated population. However, mandating that every child receive the MMR does not guarantee a measles-free population. China continues to have measles outbreaks even though Chinese children are the most vaccinated in the world—over 99% of Chinese children are fully vaccinated for measles.[ii] Furthermore, there has been a rash of mumps outbreaks across the US since 2006–all in fully vaccinated populations.[iii] In 2015-2016, 453 cases of mumps were recorded with 98% being fully vaccinated. In fact, from 2016-2017, there have been over 9,200 cases of mumps in the US, mostly from fully vaccinated people.
The author claims that “…pediatricians and public health officials have been battling fake news about vaccine safety.” US children are the most vaccinated in the world. US children have the most chronic disease when compared to other Western children. In fact, over half of US children suffer with a chronic disease.[iv] Chronic disease in children has been increasing at epidemic rates at the same time we have been rapidly expanding the US childhood vaccine schedule. Since when is it fake news to question whether the expanding vaccine schedule correlates with the increasing rates of childhood illnesses?!
The author claims that “…the same fake medical news and fearmongering also plague the cardiovascular world through relentless attacks on statins.” The author further states that a popular health website[v] “…incorrectly indicates that statins cause memory loss, cataracts, pancreatic dysfunction, Lou Gehrig disease, and cancer. Many of these sites criticize statin researchers for links to ‘big pharma’…”
The Physicians Desk Reference states that adverse reactions associated with Lipitor include the cognitive impairment (memory loss, forgetfulness, amnesia, memory impairment, and confusion associated with stain use). Furthermore post-marketing studies have found Lipitor use associated with pancreatitis.[vi] Other researchers have reported a relationship between statin use and Lou Gehrig’s disease.[vii] Finally, peer-reviewed research has reported a relationship between statin use and cataracts.[viii] Statins being associated with serious adverse effects has nothing to do with fake news. These are facts.
As for criticizing researchers for links to “big pharma” I would like to ask why is that a bad thing? Researchers studying the association between the presence of individual principal investigators’ financial ties to the manufacturer of the drug study and the trial’s outcomes have shown that financial ties of principal investigators were independently associated with positive clinical trial results.[ix] So, perhaps it is not fake news to point out that doctors should question the independence of every author and they should look critically at anyone who has financial ties to industry.
The author claims that “With the exception of a small, vocal minority, most physicians believe that statins, as with vaccines, are safe and effective.” Just because the majority of physicians believe something does not make it true. Vioxx was marketed to physicians as safer than older NSAIDs. This was ‘believed’ by a majority of physicians. The result of this belief was over 60,000 deaths and 140,000 heart attacks. Vioxx was eventually pulled from the marketplace due to the serious events it caused.
The author blames fake news because patients are concerned about statin safety. A large percentage of patients stop statin drugs due to side effects.[x] I find it doubtful that fake news is responsible for a large percentage of patients to suffer adverse effects from statin therapy. I have been a clinician for over 25 years and regularly heard patients complaining about statin adverse effects.
The author states that transparency and clear communication to patients is critical to maintain trust. I could not agree more. Perhaps the US Centers for Disease Control and Prevention can allow a senior CDC scientist William Thompson—who has claimed whistleblower protection–to testify about his claims that the CDC lied, hid, and altered data that showed the MMR vaccine when given before 36 months of age is associated with autism. The CDC has refused to allow Dr. Thompson to testify about his claims. Dr. Thompson has claimed whistleblower status. And, perhaps the CDC can comment on another Federal case where the mumps part of the MMR is in court because two Merck whistleblowers have come forward stating the Merck falsified the data on the efficacy of the mumps part of the MMR vaccine.
The JAMA author states that the medical community needs to stay vigilant. Again, I could not agree more. Vigilance with Vioxx would have saved tens of thousands of lives and prevented hundreds of thousands of heart attacks.
Questioning the wisdom, safety and efficacy of any therapy is not fake news. It is what physicians should be doing.
My friend and colleague, David Diamond, Ph.D, also took exception to the JAMA Cardiology article. We wrote (Dr. Diamond was the principal author on this reply) the following reply which was rejected by the JAMA Cardiology. Refer to the link below to read our letter to JAMA: submitted_version
[i] https://jamanetwork.com/journals/jamacardiology/article-abstract/2736328
[ii] PLOS One. 2014; 9(2): e89631
[iii] Accessed 6.28.19 from: https://www.cdc.gov/mumps/outbreaks.html
[iv] American Pediatrics. Vol. 11. Issue 3, Supplement May – June 2011. S22-S33
[v] How much do you really know about vaccine safety? https://articles.mercola.com/sites/articles/ archive/2017/12/16/how-much-do-you-knowabout-vaccine-safety.aspx.AccessedMarch27, 2019.
[vi] Accessed 6.28.19 from: http://labeling.pfizer.com/ShowLabeling.aspx?id=587#section-5
[vii] Drug Saf (2018) 41:403–413 https://doi.org/10.1007/s40264-017-0620-4
[viii] 1040-5488/12/8908-1165/0 VOL. 89, NO. 8, PP. 1165–1171 OPTOMETRY AND VISION SCIENCE
[ix] the bmj BMJ 2017;356:i6770 doi: 10.1136/bmj.i6770
[x] Annals of Int. Med. April 2, 2013. https://annals.org/aim/article-abstract/1671715/discontinuation-statins-routine-care-settings-cohort-study https://www.drbrownstein.com/from-vaccines-to-statins-a-reply-to-fake-news-in-jama-cardiology/
2019.07.11 01:03 PrestigiousProof An MD's reply to a Big Pharma Smear
An article (jamacardiology_navar_2019_vp_190009) in the June, 2019 edition of JAMA Cardiology was titled, “Fear-Based Medical Misinformation and Disease Prevention: From Vaccines to Statins. In this article,[i] the author states “fake medical news” as the reason that patients are exhibiting hesitancy about utilizing statins and vaccines.
The author correctly points out that in 1963, before the measles, mumps and rubella vaccine was licensed, there were 3-4 million people who contracted measles each year. The immunization campaign which utilizes the MMR vaccine has decreased the incidence of measles. The author blames vaccine refusers for fueling outbreaks of measles. Yes, the recent outbreak in measles has been primarily in the unvaccinated population. However, mandating that every child receive the MMR does not guarantee a measles-free population. China continues to have measles outbreaks even though Chinese children are the most vaccinated in the world—over 99% of Chinese children are fully vaccinated for measles.[ii] Furthermore, there has been a rash of mumps outbreaks across the US since 2006–all in fully vaccinated populations.[iii] In 2015-2016, 453 cases of mumps were recorded with 98% being fully vaccinated. In fact, from 2016-2017, there have been over 9,200 cases of mumps in the US, mostly from fully vaccinated people.
The author claims that “…pediatricians and public health officials have been battling fake news about vaccine safety.” US children are the most vaccinated in the world. US children have the most chronic disease when compared to other Western children. In fact, over half of US children suffer with a chronic disease.[iv] Chronic disease in children has been increasing at epidemic rates at the same time we have been rapidly expanding the US childhood vaccine schedule. Since when is it fake news to question whether the expanding vaccine schedule correlates with the increasing rates of childhood illnesses?!
The author claims that “…the same fake medical news and fearmongering also plague the cardiovascular world through relentless attacks on statins.” The author further states that a popular health website[v] “…incorrectly indicates that statins cause memory loss, cataracts, pancreatic dysfunction, Lou Gehrig disease, and cancer. Many of these sites criticize statin researchers for links to ‘big pharma’…”
The Physicians Desk Reference states that adverse reactions associated with Lipitor include the cognitive impairment (memory loss, forgetfulness, amnesia, memory impairment, and confusion associated with stain use). Furthermore post-marketing studies have found Lipitor use associated with pancreatitis.[vi] Other researchers have reported a relationship between statin use and Lou Gehrig’s disease.[vii] Finally, peer-reviewed research has reported a relationship between statin use and cataracts.[viii] Statins being associated with serious adverse effects has nothing to do with fake news. These are facts.
As for criticizing researchers for links to “big pharma” I would like to ask why is that a bad thing? Researchers studying the association between the presence of individual principal investigators’ financial ties to the manufacturer of the drug study and the trial’s outcomes have shown that financial ties of principal investigators were independently associated with positive clinical trial results.[ix] So, perhaps it is not fake news to point out that doctors should question the independence of every author and they should look critically at anyone who has financial ties to industry.
The author claims that “With the exception of a small, vocal minority, most physicians believe that statins, as with vaccines, are safe and effective.” Just because the majority of physicians believe something does not make it true. Vioxx was marketed to physicians as safer than older NSAIDs. This was ‘believed’ by a majority of physicians. The result of this belief was over 60,000 deaths and 140,000 heart attacks. Vioxx was eventually pulled from the marketplace due to the serious events it caused.
The author blames fake news because patients are concerned about statin safety. A large percentage of patients stop statin drugs due to side effects.[x] I find it doubtful that fake news is responsible for a large percentage of patients to suffer adverse effects from statin therapy. I have been a clinician for over 25 years and regularly heard patients complaining about statin adverse effects.
The author states that transparency and clear communication to patients is critical to maintain trust. I could not agree more. Perhaps the US Centers for Disease Control and Prevention can allow a senior CDC scientist William Thompson—who has claimed whistleblower protection–to testify about his claims that the CDC lied, hid, and altered data that showed the MMR vaccine when given before 36 months of age is associated with autism. The CDC has refused to allow Dr. Thompson to testify about his claims. Dr. Thompson has claimed whistleblower status. And, perhaps the CDC can comment on another Federal case where the mumps part of the MMR is in court because two Merck whistleblowers have come forward stating the Merck falsified the data on the efficacy of the mumps part of the MMR vaccine.
The JAMA author states that the medical community needs to stay vigilant. Again, I could not agree more. Vigilance with Vioxx would have saved tens of thousands of lives and prevented hundreds of thousands of heart attacks.
Questioning the wisdom, safety and efficacy of any therapy is not fake news. It is what physicians should be doing.
My friend and colleague, David Diamond, Ph.D, also took exception to the JAMA Cardiology article. We wrote (Dr. Diamond was the principal author on this reply) the following reply which was rejected by the JAMA Cardiology. Refer to the link below to read our letter to JAMA: submitted_version
[i] https://jamanetwork.com/journals/jamacardiology/article-abstract/2736328
[ii] PLOS One. 2014; 9(2): e89631
[iii] Accessed 6.28.19 from: https://www.cdc.gov/mumps/outbreaks.html
[iv] American Pediatrics. Vol. 11. Issue 3, Supplement May – June 2011. S22-S33
[v] How much do you really know about vaccine safety? https://articles.mercola.com/sites/articles/ archive/2017/12/16/how-much-do-you-knowabout-vaccine-safety.aspx.AccessedMarch27, 2019.
[vi] Accessed 6.28.19 from: http://labeling.pfizer.com/ShowLabeling.aspx?id=587#section-5
[vii] Drug Saf (2018) 41:403–413 https://doi.org/10.1007/s40264-017-0620-4
[viii] 1040-5488/12/8908-1165/0 VOL. 89, NO. 8, PP. 1165–1171 OPTOMETRY AND VISION SCIENCE
[ix] the bmj BMJ 2017;356:i6770 doi: 10.1136/bmj.i6770
[x] Annals of Int. Med. April 2, 2013. https://annals.org/aim/article-abstract/1671715/discontinuation-statins-routine-care-settings-cohort-study https://www.drbrownstein.com/from-vaccines-to-statins-a-reply-to-fake-news-in-jama-cardiology/
submitted by PrestigiousProof to conspiracy [link] [comments]
The author correctly points out that in 1963, before the measles, mumps and rubella vaccine was licensed, there were 3-4 million people who contracted measles each year. The immunization campaign which utilizes the MMR vaccine has decreased the incidence of measles. The author blames vaccine refusers for fueling outbreaks of measles. Yes, the recent outbreak in measles has been primarily in the unvaccinated population. However, mandating that every child receive the MMR does not guarantee a measles-free population. China continues to have measles outbreaks even though Chinese children are the most vaccinated in the world—over 99% of Chinese children are fully vaccinated for measles.[ii] Furthermore, there has been a rash of mumps outbreaks across the US since 2006–all in fully vaccinated populations.[iii] In 2015-2016, 453 cases of mumps were recorded with 98% being fully vaccinated. In fact, from 2016-2017, there have been over 9,200 cases of mumps in the US, mostly from fully vaccinated people.
The author claims that “…pediatricians and public health officials have been battling fake news about vaccine safety.” US children are the most vaccinated in the world. US children have the most chronic disease when compared to other Western children. In fact, over half of US children suffer with a chronic disease.[iv] Chronic disease in children has been increasing at epidemic rates at the same time we have been rapidly expanding the US childhood vaccine schedule. Since when is it fake news to question whether the expanding vaccine schedule correlates with the increasing rates of childhood illnesses?!
The author claims that “…the same fake medical news and fearmongering also plague the cardiovascular world through relentless attacks on statins.” The author further states that a popular health website[v] “…incorrectly indicates that statins cause memory loss, cataracts, pancreatic dysfunction, Lou Gehrig disease, and cancer. Many of these sites criticize statin researchers for links to ‘big pharma’…”
The Physicians Desk Reference states that adverse reactions associated with Lipitor include the cognitive impairment (memory loss, forgetfulness, amnesia, memory impairment, and confusion associated with stain use). Furthermore post-marketing studies have found Lipitor use associated with pancreatitis.[vi] Other researchers have reported a relationship between statin use and Lou Gehrig’s disease.[vii] Finally, peer-reviewed research has reported a relationship between statin use and cataracts.[viii] Statins being associated with serious adverse effects has nothing to do with fake news. These are facts.
As for criticizing researchers for links to “big pharma” I would like to ask why is that a bad thing? Researchers studying the association between the presence of individual principal investigators’ financial ties to the manufacturer of the drug study and the trial’s outcomes have shown that financial ties of principal investigators were independently associated with positive clinical trial results.[ix] So, perhaps it is not fake news to point out that doctors should question the independence of every author and they should look critically at anyone who has financial ties to industry.
The author claims that “With the exception of a small, vocal minority, most physicians believe that statins, as with vaccines, are safe and effective.” Just because the majority of physicians believe something does not make it true. Vioxx was marketed to physicians as safer than older NSAIDs. This was ‘believed’ by a majority of physicians. The result of this belief was over 60,000 deaths and 140,000 heart attacks. Vioxx was eventually pulled from the marketplace due to the serious events it caused.
The author blames fake news because patients are concerned about statin safety. A large percentage of patients stop statin drugs due to side effects.[x] I find it doubtful that fake news is responsible for a large percentage of patients to suffer adverse effects from statin therapy. I have been a clinician for over 25 years and regularly heard patients complaining about statin adverse effects.
The author states that transparency and clear communication to patients is critical to maintain trust. I could not agree more. Perhaps the US Centers for Disease Control and Prevention can allow a senior CDC scientist William Thompson—who has claimed whistleblower protection–to testify about his claims that the CDC lied, hid, and altered data that showed the MMR vaccine when given before 36 months of age is associated with autism. The CDC has refused to allow Dr. Thompson to testify about his claims. Dr. Thompson has claimed whistleblower status. And, perhaps the CDC can comment on another Federal case where the mumps part of the MMR is in court because two Merck whistleblowers have come forward stating the Merck falsified the data on the efficacy of the mumps part of the MMR vaccine.
The JAMA author states that the medical community needs to stay vigilant. Again, I could not agree more. Vigilance with Vioxx would have saved tens of thousands of lives and prevented hundreds of thousands of heart attacks.
Questioning the wisdom, safety and efficacy of any therapy is not fake news. It is what physicians should be doing.
My friend and colleague, David Diamond, Ph.D, also took exception to the JAMA Cardiology article. We wrote (Dr. Diamond was the principal author on this reply) the following reply which was rejected by the JAMA Cardiology. Refer to the link below to read our letter to JAMA: submitted_version
[i] https://jamanetwork.com/journals/jamacardiology/article-abstract/2736328
[ii] PLOS One. 2014; 9(2): e89631
[iii] Accessed 6.28.19 from: https://www.cdc.gov/mumps/outbreaks.html
[iv] American Pediatrics. Vol. 11. Issue 3, Supplement May – June 2011. S22-S33
[v] How much do you really know about vaccine safety? https://articles.mercola.com/sites/articles/ archive/2017/12/16/how-much-do-you-knowabout-vaccine-safety.aspx.AccessedMarch27, 2019.
[vi] Accessed 6.28.19 from: http://labeling.pfizer.com/ShowLabeling.aspx?id=587#section-5
[vii] Drug Saf (2018) 41:403–413 https://doi.org/10.1007/s40264-017-0620-4
[viii] 1040-5488/12/8908-1165/0 VOL. 89, NO. 8, PP. 1165–1171 OPTOMETRY AND VISION SCIENCE
[ix] the bmj BMJ 2017;356:i6770 doi: 10.1136/bmj.i6770
[x] Annals of Int. Med. April 2, 2013. https://annals.org/aim/article-abstract/1671715/discontinuation-statins-routine-care-settings-cohort-study https://www.drbrownstein.com/from-vaccines-to-statins-a-reply-to-fake-news-in-jama-cardiology/
2019.04.02 08:14 diegoldenenjude Why is it so dangerous to take a statin while pregnant?
Age- 34
Sex- female
Location- PNW, USA
Height- 5’2”
Weight- 135
Medications- Lipitor 20mg, Cyclobenzaprine 10mg, Escitalopram 15mg, Zolpidem 5mg PRN
Existing conditions- insomnia, anxiety, elevated cholesterol, intermittent neuritis/Fx coccyx, compressed lumbasacrum
Hi! I just recently had a physical with a PA at my normal medical facility. She was not my normal PA, so she went over my medication list with me. I told her my fiancé and I are thinking of becoming pregnant next year, and she told me that before we try, it’s imperative that I discontinue Lipitor. What is it about a statin that is so dangerous to take while pregnant? I have no issue discontinuing the medication, I just found it interesting because I’d never heard of any adverse side effects surrounding pregnancy
submitted by diegoldenenjude to AskDocs [link] [comments]
Sex- female
Location- PNW, USA
Height- 5’2”
Weight- 135
Medications- Lipitor 20mg, Cyclobenzaprine 10mg, Escitalopram 15mg, Zolpidem 5mg PRN
Existing conditions- insomnia, anxiety, elevated cholesterol, intermittent neuritis/Fx coccyx, compressed lumbasacrum
Hi! I just recently had a physical with a PA at my normal medical facility. She was not my normal PA, so she went over my medication list with me. I told her my fiancé and I are thinking of becoming pregnant next year, and she told me that before we try, it’s imperative that I discontinue Lipitor. What is it about a statin that is so dangerous to take while pregnant? I have no issue discontinuing the medication, I just found it interesting because I’d never heard of any adverse side effects surrounding pregnancy
2019.01.14 21:55 MaslerB Very Short Head/Neck Pain
Age: 29
Sex: Male
Height: 5'11"
Weight: 200lbs
Race: White
Location: Neck/Head
Current medical issues: Bruxism, post CVA (minor)
Current medications: Low dose aspirin, Lipitor (Plavix was discontinued by doctor two days ago)
My issue today is I yawned and had a very quick shooting, stabbing pain go from the right side of my head (felt like my brain) and travel down my neck. It all felt internal. It went as quickly as it came. It occurred around 11:30 this morning. Now, intermittently, when I yawn the pain returns for a brief moment but only in my neck and not quite as intense. I was diagnosed with bruxism several years ago and used a bite guard until it wore out. I haven't worn the guard for a few years now though. I do not have a headache. Could this be bruxism related (like an irritated nerve) or possibly due to the CVA I had last month?
If it helps...I have been cleared of a carotid dissection as cause of my stroke but the cause still has not been discovered. The CVA occurred in my right prefrontal motor cortex. Very few left sided deficits.
submitted by MaslerB to AskDocs [link] [comments]
Sex: Male
Height: 5'11"
Weight: 200lbs
Race: White
Location: Neck/Head
Current medical issues: Bruxism, post CVA (minor)
Current medications: Low dose aspirin, Lipitor (Plavix was discontinued by doctor two days ago)
My issue today is I yawned and had a very quick shooting, stabbing pain go from the right side of my head (felt like my brain) and travel down my neck. It all felt internal. It went as quickly as it came. It occurred around 11:30 this morning. Now, intermittently, when I yawn the pain returns for a brief moment but only in my neck and not quite as intense. I was diagnosed with bruxism several years ago and used a bite guard until it wore out. I haven't worn the guard for a few years now though. I do not have a headache. Could this be bruxism related (like an irritated nerve) or possibly due to the CVA I had last month?
If it helps...I have been cleared of a carotid dissection as cause of my stroke but the cause still has not been discovered. The CVA occurred in my right prefrontal motor cortex. Very few left sided deficits.
2019.01.11 23:46 MaslerB Post Stroke Medication Question
Age: 29
Sex: Male
Height: 5'11"
Weight: 200 lbs
Race: Caucasian
Duration: Stroke occurred December 10th. Some minor deficits still present, primarily left sided facial droop from eye down.
Medications: Baby Aspirin, Plavix, Lipitor
I had an ischemic stroke on December 10th, causes still unknown and I'm still undergoing some testing. Some abnormal bloodwork was found as follows:
LDL Cholesterol: 137/100 (I was on Keto before the stroke so I believe this explains it due to high fat diet)
Cardiolipin Antibody IgM: 13.5 (Doctor said this has no clinical significance)
Dilute Russell Viper Venom Time: 46 Sec (Normal <44 Sec)
Lupus Anticoagulant PTT: 51 Sec (Normal 43 Sec)
As a result I've been put on Baby Aspirin and Plavix, both 75mg doses, once a day. My vascular neurologist, the specialist I've been referred to, said that I could discontinue the Plavix after 30 days but remain on the Aspirin. He said that a study is showing that post stroke patients in my age group only benefit from the dual anti-platelet therapy for 30 days. That the Plavix does not lower my chance of recurrent stroke any further after said 30 days but my chances of hemorrhage increase greatly. I did not start taking the Plavix until the 12th or 13th of December, when it was ready at the pharmacy.
My main concern is, will the Aspirin be enough to prevent further clots from forming? I'm just a tad nervous to go off the dual therapy but the specialist did say that he sees no reason I need to be on both after 30 days. I know I can't get a 100% guarantee that I will never have another stroke but some peace of mind would be nice.
submitted by MaslerB to AskDocs [link] [comments]
Sex: Male
Height: 5'11"
Weight: 200 lbs
Race: Caucasian
Duration: Stroke occurred December 10th. Some minor deficits still present, primarily left sided facial droop from eye down.
Medications: Baby Aspirin, Plavix, Lipitor
I had an ischemic stroke on December 10th, causes still unknown and I'm still undergoing some testing. Some abnormal bloodwork was found as follows:
LDL Cholesterol: 137/100 (I was on Keto before the stroke so I believe this explains it due to high fat diet)
Cardiolipin Antibody IgM: 13.5 (Doctor said this has no clinical significance)
Dilute Russell Viper Venom Time: 46 Sec (Normal <44 Sec)
Lupus Anticoagulant PTT: 51 Sec (Normal 43 Sec)
As a result I've been put on Baby Aspirin and Plavix, both 75mg doses, once a day. My vascular neurologist, the specialist I've been referred to, said that I could discontinue the Plavix after 30 days but remain on the Aspirin. He said that a study is showing that post stroke patients in my age group only benefit from the dual anti-platelet therapy for 30 days. That the Plavix does not lower my chance of recurrent stroke any further after said 30 days but my chances of hemorrhage increase greatly. I did not start taking the Plavix until the 12th or 13th of December, when it was ready at the pharmacy.
My main concern is, will the Aspirin be enough to prevent further clots from forming? I'm just a tad nervous to go off the dual therapy but the specialist did say that he sees no reason I need to be on both after 30 days. I know I can't get a 100% guarantee that I will never have another stroke but some peace of mind would be nice.
2016.06.24 16:38 toccobrator [T2] Kidney victory
A year ago my urine had moderate levels of protein (microalbuminaria) and my doc was quite concerned, put me on ramipril, lipitor and wanted me to go on a secondary blood sugar drug (januvia or a sulfonylurea). I went full keto, started using my treadmill desk daily plus intermittent fasting, and got my blood sugar normalized, then three months ago I switched doctors to someone whose answer to every problem isn't "here is another pill". He had me stop all the pills except ramipril. My urine still had protein in it, the level had fallen but he was still concerned that I had diabetic nephropathy.
He had me do a bunch more tests to assess the situation. Just got the results -- all good! No more protein in the urine, kidneys are back to full health. Discontinued the ramipril too, and now I have no pills to take :D
submitted by toccobrator to diabetes [link] [comments]
He had me do a bunch more tests to assess the situation. Just got the results -- all good! No more protein in the urine, kidneys are back to full health. Discontinued the ramipril too, and now I have no pills to take :D
2015.09.06 21:00 chuckguy17 How to Suppress Cough in Pulmonary Fibrosis
I'm posting this on behalf of my father. He is 76 years old, 5'9", 190lbs, and white. Medications include Losartan, Lipitor, Demadex, Alendronate, and Calcium w/ Vit D. First one taken for high blood pressure. Second taken after a quadruple bypass in 2005. Last three taken after breaking hip earlier this year.
Early 2014 he was diagnosed with Follicular B-Cell Non-Hodgkin's Lymphoma with a high proliferation index. He had it throughout his body ... swollen lymph nodes under arm pits, on his neck, and his spleen was 2X the normal size. His platelets and red blood cells were both out of range because of it. They treated him with R-CHOP (Rituxan - the immunotheraphy drug, three chemotheraphy drugs, and prednisone). He did six 21-day cycles. This fully erased any trace of cancer from his body.
Around the time he was ending his last R-CHOP cycle in late 2014, he started getting a cough that wouldn't go away. They took a CT-scan and x-ray on his lungs and discovered he had inflammation in his lungs. Early 2015 they took another CT-scan and x-ray, and the radiologist wrote on the report that it looked like Idiopathic Pulmonary Fibrosis (which was scary). It looked like his lungs were a honeycomb of scar tissue. His pulmonologist put him on prednisone (which in my opinion helped his cough slightly) ... although this might have weakened his bones and contributed to breaking his hip, so he discontinued it a few months later. They took a last CT-scan and x-ray mid-2015 and had determined that his scarring had not progressed and that it wasn't IPF, just non-progressive fibrosis from one of the chemotherapy drugs (although they couldn't say which one). He has a good oxygen level during rest and exercise.
Here's the problem. He coughs thousands of times a day. His side always hurts from coughing so much. I can't talk to him on the phone without him coughing. He is always drained ... completely exhausted all the time from coughing. He can't sleep in his bed because he will cough more if he lies down ... so he sleeps upright in a chair. The coughs sound dry and unproductive. We have tried Tessalon Perles (Benzonatate), dextromethorphan, cough drops, gum, fluticasone propionate spray (in case post-nasal drip contributes), honey, Loratadine/Cetirizine (in case allergies contribute), and others that I can't think of right now. Nothing seems to do the trick. He sometimes will be able to go an hour or two without coughing, but this is rare. Every day he goes into coughing fits. I find it hard to believe there isn't something in 2015 that can effectively suppress his cough. Like I said, his oxygen is good ... the only problem is the coughing which is destroying his quality of life. Any suggestions, information, or opinions are welcome. Please help. Thanks.
submitted by chuckguy17 to AskDocs [link] [comments]
Early 2014 he was diagnosed with Follicular B-Cell Non-Hodgkin's Lymphoma with a high proliferation index. He had it throughout his body ... swollen lymph nodes under arm pits, on his neck, and his spleen was 2X the normal size. His platelets and red blood cells were both out of range because of it. They treated him with R-CHOP (Rituxan - the immunotheraphy drug, three chemotheraphy drugs, and prednisone). He did six 21-day cycles. This fully erased any trace of cancer from his body.
Around the time he was ending his last R-CHOP cycle in late 2014, he started getting a cough that wouldn't go away. They took a CT-scan and x-ray on his lungs and discovered he had inflammation in his lungs. Early 2015 they took another CT-scan and x-ray, and the radiologist wrote on the report that it looked like Idiopathic Pulmonary Fibrosis (which was scary). It looked like his lungs were a honeycomb of scar tissue. His pulmonologist put him on prednisone (which in my opinion helped his cough slightly) ... although this might have weakened his bones and contributed to breaking his hip, so he discontinued it a few months later. They took a last CT-scan and x-ray mid-2015 and had determined that his scarring had not progressed and that it wasn't IPF, just non-progressive fibrosis from one of the chemotherapy drugs (although they couldn't say which one). He has a good oxygen level during rest and exercise.
Here's the problem. He coughs thousands of times a day. His side always hurts from coughing so much. I can't talk to him on the phone without him coughing. He is always drained ... completely exhausted all the time from coughing. He can't sleep in his bed because he will cough more if he lies down ... so he sleeps upright in a chair. The coughs sound dry and unproductive. We have tried Tessalon Perles (Benzonatate), dextromethorphan, cough drops, gum, fluticasone propionate spray (in case post-nasal drip contributes), honey, Loratadine/Cetirizine (in case allergies contribute), and others that I can't think of right now. Nothing seems to do the trick. He sometimes will be able to go an hour or two without coughing, but this is rare. Every day he goes into coughing fits. I find it hard to believe there isn't something in 2015 that can effectively suppress his cough. Like I said, his oxygen is good ... the only problem is the coughing which is destroying his quality of life. Any suggestions, information, or opinions are welcome. Please help. Thanks.
2011.10.28 23:51 mistressnein Doctors of Reddit: My gf is very sick, and no doctor can explain why. Please help!
UPDATE:
GF is home from the hospital, still lethargic and having intermittent angina and frequent coughing. They changed her medication to the following: Isosorbide Dinitrate (60 mg three times daily), Amlodipine (2.5 mg daily), Aspirin (81 mg daily), Effient (10 mg daily), Verapimil (80 mg three times daily), Pantaprazole (40 mg daily), Lipitor (20 mg daily-- should she even be taking this? Her cholesterol is perfect), sublingual Nitrostat (as needed), and Advair (500 mg, twice daily). Basically, they took her off Prednisone and Plavix, and put her on a new blood thinner, Effient.
She has an appointment scheduled on Wednesday for a different cardiologist in San Francisco. I'm going to mention both Kounis Syndrome and Churg Strauss. I'm also going to ask that he test her blood for c-ANCA and p-ANCA, which might help in determining whether or not she has Churg Strauss. I'm going to ask about a higher dose of Prednisone (at least 60 mg). If we continue to experience problems with the new cardiologist, I'm going to call Kaiser and ask for a referral to a doctor at UCSF because of her unique (and potentially life-threatening) case.
Thank you all so much to everyone that responded! Any input is helpful. I'm positive that someone, somewhere, will have the last piece to this diagnostic puzzle and she'll finally be on track towards recovery. I won't stop searching. I will definitely post updates as I get more information. Thank you, thank you, thank you.
UPDATE #2:
My gf asked her cardiologist if she would be able to apply for a temporary handicapped placard for her car, so she doesn't have to walk too far (since she often gets out of breath). Today in the mail, we received a letter from her cardiologist stating what her health problems are, as well as a DMV application for the placard (a very kind gesture that I appreciate!). Here is his "Patient Active Problem" List:
ORIGINAL POST:
I’ll start from the beginning. About two years ago she was diagnosed with asthma. She started taking Monelukast (Singular) supplemented with Advair twice a day, and nebulized Albuterol as needed. About one year ago, she started to have, what she described at the time, as “heart burn.” Doctors told her she had gastro-esophageal reflux disease (GERD), and recommended she take OTC antiacids like Tums, Prilosec, etc., none of which helped much, despite avoiding acidic food. Months of persistent chest/stomach pain finally led to some lab tests. It was discovered that she had a H. Pylori bacteria infection and gastritis. She was given antibiotics, I think Cipro.
Then, suddenly this March, she had a heart attack. We were sitting on the couch at our friend’s house watching Netflix, and she complained for hours about a foreign-body sensation in her throat. She started coughing a lot and having asthma problems. We decided to go to the hospital for her asthma; it was then that she passed out in the admitting area. She had an angiogram and angioplasty. She was diagnosed with the following: retroperitoneal hematoma, GERD, prinzmetal’s angina, and hx of percutaneous transluminal coronary angioplasty [severe lesion proximal RCA—4.0 x 32 mm Taxus drug eluting stent expanded to 4.0 mm, spasm initially seen in LAD—not present at final angiogram, moderate inferobasilar wall motion abnormality with EF of approx 50%, angioseal deployed (6 Fr)]. She stayed in the hospital for a few days. She was put on the following medications: Asprin, Clopidogrel, Diltiazem, Famotidine, Simvastatin, and sublingual Nitroglycerin as needed.
Since then, she has been hospitalized over twenty times with recurrent chest pain (luckily we have insurance), each time with elevated Troponin levels and eosinophilia. Nitroglycerin helps a bit, but not much (she usually has to take it 6-7 times a day). She has had her medicine changed back and forth each time. She’s been on several different forms of Isosorbide. Doctors say that her heart itself doesn’t seem to be a problem; the problem is that her coronary arteries are spasming and restricting oxygen to her heart. At one point it was suspected that she had vasculitis (Churg-Strauss Syndrome), but since she can’t have a biopsy (she's on blood thinners), they couldn’t make a conclusive diagnosis. They put her on Prednisone anyway, which seemed to help for awhile, then stopped working. She has seen multiple cardiologists, rheumatologists, and other specialists, none of which understand what’s going on. She has had five angiograms. On some of the angiograms you can’t even see her arteries, they’re so constricted. I have a couple pictures of her angiograms that I can scan tomorrow if it’s helpful.
We are running out of options and time. She has become lethargic, her quality of life has severely deteriorated, and it’s killing me to see her covered in brusies from being on Plavix, crying in her hospital bed because the pain is unbearable. I just want her to be the happy, healthy person she used to be… She’s in the hospital now once again and doctors are now thinking about retracting their initial diagnosis of prinzmetal’s angina because of her age. I’m lying in bed, home from work, feeling hopeless. I don't have any medical training, but I've been searching through a lot of medical journals the past few months, hoping to find something relevant or overlooked. I haven't yet. I really don’t know what to do anymore other than sit here and write this as I cry.
Doctor’s of Reddit, what can we do? What do you think? We live in the SF Bay and have Kaiser Insurance. Is anyone interested in delving deeper into her case?
Other facts that might be useful:
submitted by mistressnein to Health [link] [comments]
GF is home from the hospital, still lethargic and having intermittent angina and frequent coughing. They changed her medication to the following: Isosorbide Dinitrate (60 mg three times daily), Amlodipine (2.5 mg daily), Aspirin (81 mg daily), Effient (10 mg daily), Verapimil (80 mg three times daily), Pantaprazole (40 mg daily), Lipitor (20 mg daily-- should she even be taking this? Her cholesterol is perfect), sublingual Nitrostat (as needed), and Advair (500 mg, twice daily). Basically, they took her off Prednisone and Plavix, and put her on a new blood thinner, Effient.
She has an appointment scheduled on Wednesday for a different cardiologist in San Francisco. I'm going to mention both Kounis Syndrome and Churg Strauss. I'm also going to ask that he test her blood for c-ANCA and p-ANCA, which might help in determining whether or not she has Churg Strauss. I'm going to ask about a higher dose of Prednisone (at least 60 mg). If we continue to experience problems with the new cardiologist, I'm going to call Kaiser and ask for a referral to a doctor at UCSF because of her unique (and potentially life-threatening) case.
Thank you all so much to everyone that responded! Any input is helpful. I'm positive that someone, somewhere, will have the last piece to this diagnostic puzzle and she'll finally be on track towards recovery. I won't stop searching. I will definitely post updates as I get more information. Thank you, thank you, thank you.
UPDATE #2:
My gf asked her cardiologist if she would be able to apply for a temporary handicapped placard for her car, so she doesn't have to walk too far (since she often gets out of breath). Today in the mail, we received a letter from her cardiologist stating what her health problems are, as well as a DMV application for the placard (a very kind gesture that I appreciate!). Here is his "Patient Active Problem" List:
- Degenerative Disc Disease, Lower Back (But her primary care physician said arthritis? Are these the same things?)
- Asthma
- Case/care mgmt, Asthma, Level 2
- Hx of percutaneous transluminal coronary angioplasty
- GERD
- Angina, Prinzmetal
- MI, < 8 weeks (it's actually well beyond 8 weeks, but okay...)
- Eosinophilia
- Leukocytosis
- Acute coronary syndrome (first time I've heard of this!)
- MI, acute, non ST segment elevation
- CAD (I assume this stands for coronary artery disease... is this the same as atherosclerosis? We were told that she didn't have atherosclerosis)
ORIGINAL POST:
I’ll start from the beginning. About two years ago she was diagnosed with asthma. She started taking Monelukast (Singular) supplemented with Advair twice a day, and nebulized Albuterol as needed. About one year ago, she started to have, what she described at the time, as “heart burn.” Doctors told her she had gastro-esophageal reflux disease (GERD), and recommended she take OTC antiacids like Tums, Prilosec, etc., none of which helped much, despite avoiding acidic food. Months of persistent chest/stomach pain finally led to some lab tests. It was discovered that she had a H. Pylori bacteria infection and gastritis. She was given antibiotics, I think Cipro.
Then, suddenly this March, she had a heart attack. We were sitting on the couch at our friend’s house watching Netflix, and she complained for hours about a foreign-body sensation in her throat. She started coughing a lot and having asthma problems. We decided to go to the hospital for her asthma; it was then that she passed out in the admitting area. She had an angiogram and angioplasty. She was diagnosed with the following: retroperitoneal hematoma, GERD, prinzmetal’s angina, and hx of percutaneous transluminal coronary angioplasty [severe lesion proximal RCA—4.0 x 32 mm Taxus drug eluting stent expanded to 4.0 mm, spasm initially seen in LAD—not present at final angiogram, moderate inferobasilar wall motion abnormality with EF of approx 50%, angioseal deployed (6 Fr)]. She stayed in the hospital for a few days. She was put on the following medications: Asprin, Clopidogrel, Diltiazem, Famotidine, Simvastatin, and sublingual Nitroglycerin as needed.
Since then, she has been hospitalized over twenty times with recurrent chest pain (luckily we have insurance), each time with elevated Troponin levels and eosinophilia. Nitroglycerin helps a bit, but not much (she usually has to take it 6-7 times a day). She has had her medicine changed back and forth each time. She’s been on several different forms of Isosorbide. Doctors say that her heart itself doesn’t seem to be a problem; the problem is that her coronary arteries are spasming and restricting oxygen to her heart. At one point it was suspected that she had vasculitis (Churg-Strauss Syndrome), but since she can’t have a biopsy (she's on blood thinners), they couldn’t make a conclusive diagnosis. They put her on Prednisone anyway, which seemed to help for awhile, then stopped working. She has seen multiple cardiologists, rheumatologists, and other specialists, none of which understand what’s going on. She has had five angiograms. On some of the angiograms you can’t even see her arteries, they’re so constricted. I have a couple pictures of her angiograms that I can scan tomorrow if it’s helpful.
We are running out of options and time. She has become lethargic, her quality of life has severely deteriorated, and it’s killing me to see her covered in brusies from being on Plavix, crying in her hospital bed because the pain is unbearable. I just want her to be the happy, healthy person she used to be… She’s in the hospital now once again and doctors are now thinking about retracting their initial diagnosis of prinzmetal’s angina because of her age. I’m lying in bed, home from work, feeling hopeless. I don't have any medical training, but I've been searching through a lot of medical journals the past few months, hoping to find something relevant or overlooked. I haven't yet. I really don’t know what to do anymore other than sit here and write this as I cry.
Doctor’s of Reddit, what can we do? What do you think? We live in the SF Bay and have Kaiser Insurance. Is anyone interested in delving deeper into her case?
Other facts that might be useful:
- 28 year old southeast Asian female
- History of smoking from age 17 to age 27 (quit before heart attack)
- Experiences angina every day, but angina increases during menstrual period. Also, her heart attack occurred while she was on her period. I asked if she could be put on the birth control pill to increase her estrogen levels, but her doctors said that would do more harm than good.
- Stress test has always been normal. Angina occurs mostly at rest, but can also during activity.
- Current medications: Verpamil, Simvastatin, Isosorbide Dinitrate, Prednisone 10 mg, Aspirin 325 mg, Nitrostat (as needed), Proair as needed) , Advair 500 mg, Plavix.
- Discontinued medications: Metroprolol, Singulair, Amlodipine, Famotidine, Pantoprazole, Diltiazem, probably some others that I’m forgetting.
- Persistent cough that doesn’t respond well to asthma medication
- No skin problems observed
- No Raynaud’s Phenomenon
- No Barrett’s esophagus
- Kidneys and liver normal
- Most recent (as of yesterday) eosinophil count: 25%
- Lipid panel is normal
- ALT, AST, alkaline phosphate is normal
- Erythrocyte sedimentation rate is normal