Voltaren retard novartis

Υπαρχει μου φαινεται ελειψη σε αυτο το φαρμακο ρε παιδια? Ολοι οι φαρκακοποιοι μου ριχνουν ακυρο😢

2024.03.29 13:35 Apprehensive_Toe6736 Υπαρχει μου φαινεται ελειψη σε αυτο το φαρμακο ρε παιδια? Ολοι οι φαρκακοποιοι μου ριχνουν ακυρο😢

Υπαρχει μου φαινεται ελειψη σε αυτο το φαρμακο ρε παιδια? Ολοι οι φαρκακοποιοι μου ριχνουν ακυρο😢 submitted by Apprehensive_Toe6736 to greececirclejerk [link] [comments]


2023.06.09 14:25 Haanipoju /unretard cure 🤤💊

/unretard cure 🤤💊 submitted by Haanipoju to okbuddyretard [link] [comments]


2022.12.31 13:26 ifuckparrotz I got my meds bajs

I got my meds bajs submitted by ifuckparrotz to forsen [link] [comments]


2022.12.31 00:57 Trini_YellowRanger HEY RETARD

HEY RETARD submitted by Trini_YellowRanger to howardstern [link] [comments]


2022.12.31 00:36 RV12321 Good news for Taylor. They finally have a cure!

Good news for Taylor. They finally have a cure! submitted by RV12321 to PKA [link] [comments]


2022.12.30 21:27 DrDonTango Now sold under the new name of “Voltaren Down Syndrom”

Now sold under the new name of “Voltaren Down Syndrom” submitted by DrDonTango to NormMacdonald [link] [comments]


2022.03.28 22:18 somerandomie Adderall 30mg and voltaren xr 100 interactions

I am 30m, 78kg, 170cm.
I am having some back pains due to wrongly picking up some heavy items last week. I am currently on Adderall XR 30mg, and would like to take a Voltaren Retard XR 100 for the pain, I am wondering if there are any negative interactions I should be aware of?
I tried google, there doesnt seem to be any known interactions https://www.drugs.com/drug-interactions/adderall-with-voltaren-xr-190-1645-869-4640.html#:~:text=Interactions%20between%20your%20drugs,between%20Adderall%20and%20Voltaren%2DXR.
How much can I rely on this data? has it been looked into or is it "unknown" and I should not risk mixing the meds? would appreciate a professional input.
submitted by somerandomie to AskDocs [link] [comments]


2022.03.24 07:54 thelansis Activated PI3Kdelta Syndrome (APDS) – Market outlook, Epidemiology, Competitive Landscape, and Market Forecast Report – 2020 To 2030

Activated PI3Kdelta Syndrome (APDS) – Market outlook, Epidemiology, Competitive Landscape, and Market Forecast Report – 2020 To 2030


Activated PI3Kdelta Syndrome (APDS), also known as PASLI disease, is a combined immunodeficiency resulting from dominant, gain-of-function mutations in the genes encoding p110δ (PIK3CD) and p85α (PIK3R1), the catalytic and regulatory subunits of phosphoinositide 3-kinase δ (PI3Kδ). These mutations result in the hyperactivation of the PI3K/AKT/mTOS6K signally pathways in immune cells. Patients with APDS may develop immune-deficient and immune-dysregulation features, including recurrent respiratory tract infections, bronchiectasis, herpesvirus infections, autoimmunity, non-neoplastic lymphoproliferation, and lymphoma as neurodevelopment delay and growth retardation. APDS due to gain-of-function mutations in the genes encoding p110δ (PIK3CD) and p85α (PIK3R1) are termed APDS1 and APDS2, respectively. There is no curative therapy for APDS. However, Treatment regimes for APDS patients include antibiotic prophylaxis and immunoglobulin replacement therapy. Hematopoietic stem cell transplantation (HSCT) has succeeded several APDS patients and can be a treatment option, especially in young patients.
In the United States, 1.75 to 2.3 patients are being diagnosed per million populations. Patients with APDS had a high incidence and wide range of inflammatory/autoimmune manifestations.
The competitive landscape of Activated PI3Kdelta Syndrome (APDS) includes country-specific approved and pipeline therapies. Any asset/product-specific designation or review and Accelerated Approval are tracked and supplemented with analyst commentary.
KOLs insights of Activated PI3Kdelta Syndrome (APDS) across 8 MM market from the center of Excellence/ Public/ Private hospitals participated in the study. Insights around current treatment landscape, epidemiology, clinical characteristics, future treatment paradigm, and Unmet needs.
Activated PI3Kdelta Syndrome (APDS) Market Forecast: Patient Based Forecast Model (MS. Excel Based Automated Dashboard) which Data Inputs with sourcing, Market Event, and Product Event, Country specific Forecast Model, Market uptake and patient share uptake, Attribute Analysis, Analog Analysis, Disease burden, and pricing scenario, Summary, and Insights.
Read more: Activated PI3Kdelta Syndrome (APDS) – Market outlook, Epidemiology, Market Forecast, and Competitive Landscape Report – 2020 To 2030
S. No Asset Company Stage
1 leniolisib Pharming Group N.V Phase 2/3
2 Nemiralisib GlaxoSmithKline Phase 2
3 CDZ173 Novartis Pharmaceuticals Phase 2/3
submitted by thelansis to u/thelansis [link] [comments]


2022.02.21 11:38 thelansis Rett syndrome (RTT) – Market outlook, Epidemiology, Competitive Landscape and Market Forecast Report – 2020 To 2030

Rett syndrome (RTT) – Market outlook, Epidemiology, Competitive Landscape and Market Forecast Report – 2020 To 2030


Rett Syndrome (Also called: RTS, Cerebroatrophic Hyperammonemia) is a rare, non-inherited, X-linked dominant neurological disorder affecting brain development only in girls and is one of the most common causes of mental retardation in females. Girls with the syndrome show normal development during the first 6-18 months of life followed first by a period of stagnation and then by rapid regression in motor and language skills. The hallmark of Rett syndrome is the loss of purposeful hand use and its replacement with stereotyped hand-wringing. Screaming fits and inconsolable crying are common. With this syndrome, the girls typically survive into adulthood but are at risk of sudden unexplained death.
Etiology-
Rett Syndrome is caused by a mutation within the Methylcytosine-binding protein 2 (MECP2) gene. The MECP2 gene is located on the X chromosome. Between 90% and 95% of girls with Rett syndrome have a mutation in the MECP2 gene. Among families with a child affected by Rett syndrome the chance of having a second child with the syndrome is very low. Eight mutations in the MECP2 gene represent the most prevalent causes of Rett syndrome. The development and severity of Rett syndrome symptoms depend on the location and type of the mutation on the MECP2 gene
Epidemiology-
According to the published articles of Rett Syndrome Research Trust, the incidence of Rett Syndrome is estimated at 1 in 10,000 females; in the United States, approximately 30,000 children and women are affected by the condition. As per Chahil G and Bollu PC, et al, says that approximately 90% of reported cases of RTT inherit mutations of the methyl-CpG-binding protein 2 (MECP2) gene. The diagnosis of Rett syndrome is still based on clinical criteria and clinical presentation. Over 95% of females with classic Rett syndrome will have a mutation in the MECP2 gene
The competitive landscape of Rett syndrome (RTT) includes country-specific approved as well as pipeline therapies. Any asset/product-specific designation or review and Accelerated Approval are being tracked and supplemented with analyst commentary.
KOLs insights of Rett syndrome (RTT) across 8 MM market from the center of Excellence/ Public/ Private hospitals participated in the study. Insights around current treatment landscape, epidemiology, clinical characteristics, future treatment paradigm, and Unmet needs.
Rett syndrome (RTT) Market Forecast: Patient Based Forecast Model (MS. Excel Based Automated Dashboard) which Data Inputs with sourcing, Market Event, and Product Event, Country specific Forecast Model, Market uptake and patient share uptake, Attribute Analysis, Analog Analysis, Disease burden, and pricing scenario, Summary, and Insights.
Read more: Rett syndrome (RTT) – Market outlook, Epidemiology, Market Forecast, and Competitive Landscape Report – 2020 To 2030
S. No Asset Company Stage
1 trofinetide ACADIA Pharmaceuticals Inc. Phase 3
2 NNZ-2566 Neuren Pharmaceuticals Limited Phase 2
3 EPI-743 Edison Pharmaceuticals Inc Phase 2
4 ANAVEX2-73 Anavex Life Sciences Corp. Phase 2
5 fingolimod (FTY720) Novartis Phase 2
6 triheptanoin Ultragenyx Pharmaceutical Inc Phase 2
submitted by thelansis to u/thelansis [link] [comments]


2021.02.01 11:07 decs555 IMMP cancer fighting stock targeted by shorts up 558% in January!

Hi fellow retards I am fighting this war along you fellas with AMC and I trully believe that shorting stocks should be illegal,, how can you sell something that you don't even own!!
But worse is to short stocks/companies that are trying to fight cancer.. $IMMP increased by 558% jist in January.. this is ridiculous!
These guys are trying to short actually companies that are trying to promote health and become this world a better place.. i enlisted some progress from the company here below so you can see that they are doing pretty well.
About Immutep:
They have 4 main products seeking commercialisation:
1.- IMP321, known as eftilagimod alpha - immunotherapy for cancer 2.- IMP761 - preclinical immunotherapy for autoimmune disease 3.-IMP701, known as LAG525 - immunotherapy for solid tumors, blood cancer and breast cancer (partnered with Novartis) 4.- IMP731, known as GSK‘781 - immunotherapy in ulcerative colitis (partnered with GSK)
website
Let's get these shorts! Trying to ruin cancer fighting stocks!!!
submitted by decs555 to WallStreetbetsELITE [link] [comments]


2021.01.13 10:17 PurpIeMonkeyBalls SGMO might 🚀 at 9am PST

SGMO might 🚀 at 9am PST
I'll keep this short since there were a couple of SGMO DD posts in December and you guys can't read.
  1. SGMO is presenting at JPM (JP Morgan Healthcare Conference) tomorrow at 9am PST and they will receive widespread attention from many pharma investors. While everyone jizzing at the seams about their EDIT, NTLA and CRISPY returns, they may not be aware that there are potentially hazardous effects of using this genomic editing tech. (You go in to be treated for testicular cancer and then you grow a dong on your forehead) Also SGMO owns many of the patents to the other three gene-editing companies above. Despite this, they continue to work on Zinc Finger Nuclease, which is more expensive and labor intensive. This may be indicative of its long term success, since it is safer and has a longer track record in clinical trials. (I don't want to explain the nuance here, I trust my 2.7 GPA Bio friends) In this clown market, everyone is chasing stocks that are up 420% for the year, no one wants to touch a beaten down underrated company that is pursuing potentially much more lucrative long term production. The price collapsed in 2018 because they only kind of cured HIV with gene-editing. One of their collaborators, University of Pennsylvania is also accepting patients for a new HIV trial which may be huge news if it drops on tomorrow's conference.
  2. The sharks are circling. SGMO has a partnership with Gilead, Biogen, Pfizer, Novartis, Takeda and Sanofi. All have dumped millions into their gene-editing pipelines. Biogen is in an interesting place, as they own 17% of SGMO, giving them an enormous bidding advantage. CEO said he's open to acquisition and the CFO quit for personal reasons, which is odd right before a big event like JPM and while everyone is working remote (I assume). Around 20% of CFO resignations are for M&A. Oh and there was a massive Block Order over $20 when it peaked two weeks ago.
  3. Some retard shorted the first day it spiked on the 10th, see below. Since then, the price is over 50% higher and whoever has this position must be sweating, especially with the long list of catalysts (listed above) that could rocket the price in the near future. In the last two weeks without fail, there is a large sell order at market open. I hate to use the M word but if they are trying to shake out paper hands, it is working handsomely as 90% of WSB call holders that I have heard from so far have sold at a loss . You know the cycle, stock spikes WSB fomo's, stock drops -> paper hands then 🚀 again and the cycle repeats. There was also a weak 'Analyst Downgrade' report last week that was paid for with little reasoning for the downgrade.

https://preview.redd.it/p3mj9ble52b61.png?width=653&format=png&auto=webp&s=abb6316d1b2f03a1596fa103f263e83d6838c69a

  1. Be careful with this stock. Bears are desperate and people think of it as that lame boomer tech company that is still somehow alive, don't all-in. The market cap is 2.4B which pales in comparison to CRSP's 12B so there's lots of room to run. As for TA, there's a bullflag or something. There is definitely resistance at $20 which is what the Bears seem to be defending from a break out (lots of interest above $20 because clown market). Support at $15 seems strong, at least I keep buying there. I will be waiting with the buy button to buy more while watching the conference.

TL;DR
SGMO 30C 2/19/21 🚀🚀🚀🚀🚀🚀🚀🚀🚀🚀🚀🚀 🚀🚀🚀🚀🚀🚀🚀🚀🚀🚀🚀🚀
Big conference tomorrow. Massive block orders. Big pharma circling and a possible buyout. Quality long term company. Bears in over their head and trying to cover before it's too late.

Positions:
Garden Variety of Jan and Feb Calls (Whatever is a steal), $1.5K total and ready to drop $2k more tomorrow on a dime.
1,000 Shares at $15.5 avg (yes I bought the spike)
submitted by PurpIeMonkeyBalls to wallstreetbets [link] [comments]


2020.12.21 03:19 Rake-7613 SGMO- Investment Thesis- Full DD

SGMO- Investment Thesis- Full DD
  • Wtf is SGMO? It’s the most drastically undervalued gene therapy company on the market. They edit genes with zinc finger nucleases, a technology distinctly different from crispr.
  • Zinc Finger? It’s theoretically better than crispr. More specificity and less off-target edits than crispr, but years of reading investor village posts and the occasional research paper aren’t easily summarized. And how it works doesn’t really change the thesis here.
  • Why is it undervalued? Check out the market cap and past year’s price action of the competitors in the field

Ticker Market Cap
BMRN 16 B
CRSP 10.5 B
ONCE Acquired for 4 B
EDIT 4 B
NTLA 3 B
SGMO 2 B

  • Why is BMRN on there? Because Biomarin is SGMO’s largest competitor for Hemophilia A gene therapy, which also happens to SGMO’s closest to market product. But, surprise, SGMO has better data than BMRN! This year they reported higher sustained clotting factor levels and no bleeds within the first 52 weeks for the highest dose level of SB-525. Biomarin’s patients are having bleeds and requiring factor, and because of it (and the much better data from SGMO) BMRN got a rejection from the FDA when they tried to get accelerated approval to beat SGMO to market: https://www.reuters.com/article/us-biomarin-pharma-fda/u-s-fda-rejects-biomarin-hemophilia-a-gene-therapy-shares-dive-idUSKCN25F1H6 BTW, the SGMO Hemophilia A gene therapy program is also partnered with *Pfizer*
  • Partnered with Pfizer? Yeah, and Takeda. And Kite therapeutics. And Novartis. And Sanofi. And Biogen. I’m retarded, but highly doubt those 5 big pharma partners and their entire team of scientists and capital allocation programs are as retarded as me. Look at the pipeline page: https://www.sangamo.com/pipeline And just for good measure, the Biogen/SGMO collaboration also included Biogen acquiring so much SGMO stock that Biogen owns like 17% of the damn company!!!! Acquisition rumors abound…and if you look at the table above most of those other names don't have anywhere near the number of partnerships/pipeline programs SGMO has.
  • Biogen partnership is for multiple neurological diseases, including Alzheimer’s, the single largest unmet need in medicine today. And Biogen didn’t fuck around with crispr for it.
  • Speaking of pipeline, I hope you clicked on the link to the pipeline page. Aside from the Phase 3 trial with Pfizer, they have four Phase 1 or 2 trials, and 13 disclosed preclinical trials. And 7 wholly-owned (not partnered) programs. And an estimated 600-700 million cash runway, with the expenses for the phase 3 program with Pfizer covered by Pfizer, and a potential reimbursement of a few hundred thousand to $1 million plus per patient (still cheaper than replacement factor infusion therapy).
  • Why isn’t this worth more? I dunno, but I can guess. CRSPR was featured on Radiolab and had some articles written about it a few years ago, and has had enough press that most people have heard of it in passing. SGMO also had some false starts, once a long time ago when they were basically a different company trying to tackle some bullshit like diabetic neuropathy. Another time when they were trying to do gene editing in live patients for MPS II (the CHAMPIONS ½ trial) that didn’t have great results. Yes, they are trying to edit genes in live humans. Turns out it’s hard. And yes, it worked via detection of targeted integration via liver biopsy, but had not edit enough cells to be clinically significant (they’re still working on it).
  • What else are they working on? T-cell therapies, which can address anything from transplant rejection (their wholly-owned TX200 trial) to autoimmune diseases (IBD, also wholly owned). They bought the company TX Cell for 84 million in 2018 for this purpose.
  • So why the hell are you telling me about this now? Last couple weeks have been weird and SGMO has been taking off. Look at the last year specifically this month- it fucking rocketed off, pulled back, and has started to climb again. Price action on this stock has always been super wonky. If you follow it as close as I do, you’d notice the huge price spike happened *after* they reported the positive Hemophilia A data at ASH Dec 7th- the price spiked Dec 10th.
  • Anything else going to make the price rocket up? Aside from the fact that every gene therapy company chart has been a goddamn hockey stick this year, here’s some events: https://www.investorvillage.com/smbd.asp?mb=1933&mn=152550&pt=msg&mid=21430904
  • Also, its not in the ARKG gene therapy fund yet, but theres a good chance Cathie Wood might shift profits from other names to SGMO #1 to diversify and #2 because it’s comparatively cheap as shit.
  • Speaking of price, HCW just gave it a $25 price target. Truist gave it price target $23. Some badass analyst with huge nuts had it at $36. The average is like $21. Mine personally is $25 this year and $45 long term. Here’s some undiagnosed autist on IV making a case: https://www.investorvillage.com/smbd.asp?mb=1933&mn=152920&pt=msg&mid=21447148
  • Yeah but do you own any, you kooky fuck with a wizard avatar? Yeah, I have 2500+ shares, 25+ ITM calls, and 40+ OTM calls across all my accounts. I attached a screenshot from my traditional IRA. It’s most of my tradeable retirement. Not sure if this counts as YOLO? I feel like I’m wearing a life helmet at this point having held and accumulated this shit for 3+ years and finally seeing it take off.
  • Thesis summary; SGMO is undervalued. They have superior gene editing technology and a shit ton of shots on target in their huge pipeline with 5 big pharma partners, and they are getting close to hemophilia A gene therapy being commercialized in early 2022. Even if they completely fuck up more than half their pipeline they’re still undervalued.
  • TLDR; why to invest in SGMO: https://www.sangamo.com/pipeline
  • TLDR; Buy SGMO now. LEAPs > short term, this stock trades weird and I don’t know how soon it will rocket off, but started to launch a couple weeks ago. Shares are still cheap. Don’t buy calls too far OTM in case of buyout. May and August calls in the $17-$20 range seem cheap. Jan’22 $20 strike looks good to me, or Jan’23 $25 strike. $20 conservative price target by year-end 2021. Long term price target $45.
  • Note: the original post got banned because I updated it and used a four-letter word that was a banned ticker. I'm sorry to anyone that commented on that one.

https://preview.redd.it/uy7mib749g661.jpg?width=939&format=pjpg&auto=webp&s=4b3ff20c8177d57f5c4443fd1177e62767876934
submitted by Rake-7613 to wallstreetbets [link] [comments]


2020.10.28 11:57 nightystorm1 Novartis teams up with Molecular Partners (MOLN.SW) against COVID

So back in April, Molecular Partners announced that they will be remodeling their new innovative drugs to create a treatment for covid. (I'm not a biotech expert so go read the articles if you want more details)
Now Novartis announced that they have been granted an option to in-license global rights to these drugs. Molecular Partners will lead the first clinical trials in November, followed by Novartis handling the 2nd and 3rd trials.
- The person behind Molecular Partners is the billionaire Jackson Hansjoerg Wyss, former CEO and founder of Synthes.
- There's a Harvard building to his name (The Wyss Institute for Biologically Inspired Engineering), so the guy must be legit.
- Here's an interesting detail "with the possibility to manufacture at scale, easy administration and with the potential to bypass cold storage" boom logistics problem associated to vaccines solved
- and most importantly: Molecular Partners has a mkt cap of only 420M, so could easily go to the moon
Thank you for having read my very in-depth and technical analysis
Cheers retards
Disclaimer: I'm balls deep in this motherfucker, so absolutely not biased at all
sources:
https://www.globenewswire.com/news-release/2020/10/28/2115640/0/en/Novartis-announces-collaboration-with-Molecular-Partners-to-develop-two-DARPin-therapies-designed-for-potential-use-against-COVID-19.html
https://www.accesswire.com/585828/Molecular-Partners-Initiates-Anti-COVID-19-Therapeutic-Program-Leveraging-Multi-Target-Binding-of-DARPinR-Proteins-to-Neutralize-SARS-CoV-2-Virus
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2020.04.08 13:28 Wojtaz69 My Medicine List

Here is a shortlist of Meds I like to keep in stock for this type of situation. If you have any questions I’d be more than happy to answer them. As I said this is a shortlist that applies to me. There could be other necessary meds. But I either can’t get them or I don’t need them.
Medication List
Steroids Halobetasol Propionate 0.05% 30g x 3 Betamethasone 0.5mg x 400 Beclomethasone 100mcg spray x 200 x4
NSAIDs Celecoxib 200mg x 100 Voltaren Retard 100mg x 30 Voltaren Forte 100g x 3 Loxonin 60mg x 100
Pain Meds Tramadol 50mg x 100 x 2 Carisprodol 375mg x 100 x 2
Other Sodium Liothyronine 25mcg x 90 x 3
Stomach Omeprazole 20mg x 28 x 3 Loperamide 2mg x 30 Famotidine 40mg x 294
Asthma Clenbuterol HCL 40mcg x 90 x 2 Montelukast 10mg x 150 Ventolin 200回 x 3
Sleep Toficalm 50mg x 100 x 2 Trazodone 50mg x 100 Eszopiclone 3mg x 30 x 3 Eszopiclone 3mg x 100 Olanzapine 10mg x 100
Antibiotics Ciprofloxacin 0.3% drops x 6 Ciprofloxacin 500mg x 100 Amoxicillin 500mg x 21 x 3 Metronidazole 200mg x 21 x 5 Cephalexin 250mg x 200
Antihistamines Diphenhydramine HCL 25mg x 600 Fexofenadine 180mg x 20 x 3
submitted by Wojtaz69 to preppers [link] [comments]


2020.04.03 07:17 teezar420 This Crash has Been In The Works for YEARS

This Crash has Been In The Works for YEARS
Sup retards. I know you’re freaking out about your tendies after you completely misunderstood what u/variation-separate said regarding today being, what he thought to be, “the most important trading day of the year.” For an explanation as to what he meant by that, check out his comments on his most recent big 🐻 🌈 star(oil)wars post. That’s not what this is about.
This post should bring you gay bears more comfort than the can of paint you huff every night while you watch your wife get rammed by her hairy-assed boyfriend. So buckle up (as in, your helmets) and break out the Jergens, because we’re about to get our jerks in to these gains the next few weeks and months.
This Crash Has Been In The Making for a Long Time
I know you gaggle of fuckatrons are jacked to the tits in SPY puts and as such, only care about U.S. large cap companies. We all are rather familiar with the success these companies have been benefiting from over the last few years, and the bulls have been jacking their peens to no end over it. Let me peel your eyes off of your RobinHood portfolio and your (at the moment, free) PornHub premium account to look at the performance of global markets for the past decade or so.
EFA, 1M Candles
EFA is an ETF with exposure to securities in Europe, Australia, and the Far East. Some notable names of their 923 holdings include Nestle, Novartis (pharmaceutical company), and Toyota. What’s important about this ETF is that it excludes U.S. and Canada securities. If you want to know more about about it, since I know you’re too incompetent to find the big fucking search bar at the top of your browser, here you go: https://www.etf.com/EFA#overview.
Take a look at the chart, particularly post 2007. It’s essentially been trading sideways ever since, with its most recent peak (marked by the big 🌈 magenta line) being lower than it was in 2007. Speaking of its most recent peak, take a look at the date of that peak at the bottom of the beautiful magenta line. This ETF has been on the decline since January of 2018.
Okay, perhaps that’s a coincidence. Maybe Toyota and Nestle haven’t been sucking enough JPOW BRR printer dick to get their share of that unlimited under-the-table QE.

EEM, 1M Candles
EEM is another ETF that tracks investments of emerging market firms. It’s almost entirely represented by Hong Kong, Taiwan, Korea, India, and China. Most notable of its 1225 holdings include Alibaba, Samsung, and Tencent (info here: https://www.etf.com/EEM#efficiency) Again, we see that it has traded sideways since 2007 and has been on the decline since January of 2018. Let's go bigger.

Courtesy of Rodney E. Constable
This is the MSCI world index excluding U.S. holdings. This index captures large and mid cap stocks across 22 of 23 developed market countries. It, too, has traded sideways since 2007 and has been on the decline since 2018. I could go on.
All this is to say, this is a long time coming. As to the why, the short answer is who the fuck knows? The longer answer is likely multi-factorial, resulting from a failure to adequately rectify the fiscal policy shortfalls that caused the ‘08 recession. Lending to those who shouldn’t be lended to in large amounts and being surprised when the whole shebang goes tits up, then slapping a band-aid on the issue by slashing interest rates and creating stimulus packages (sound familiar?) Let’s not even bother reinstating laws like the Glass-Steagall act that many economists believe would have prevented it all to begin with, let’s just fix it long enough to make it someone else’s problem after the boomers die or retire. The failure to eliminate the underlying causes of the ‘08 crash has had the global economy teetering on the re-entry into a full blown recession for years, but no one gives a fuck here in the states because all we care about are the U.S. large caps. Ya know, ‘murica and all that bud-light-drinkin’ shit. Stonks be goin up, all is gud.
Thanks For The History Lesson, but Who Fucking Cares?
I’m glad you asked. Speaking of history, the average length of a bear market is 10 months (1). Although, averages can be inflated a lot by outliers, like the 1929 bear market that lasted 61 months (2). The shortest ever bear market was 3 months in 1990, and was mostly due to central banking policy attempting to wrangle inflation like automod wrangles you autists and the invasion of Saddam Hussein into Kuiwait, causing a spike in oil prices (3). We are hardly 6 weeks into this bear market and, needless to say, these are very different circumstances.
This is not an issue that can be band-aided through stimulus packages and slashed interest rates. All these years of high-risk lending is going to dick everyone down by these cuts in production caused by the beervirus. I sincerely believe that the Fed and the gov’t in general are just delaying the inevitable (and vegafucking my tendies) under the aforementioned retarded boomer logic.
We’re in it for the long haul boys. Diamond hands.
Tl;Dr Learn to read, it’s not that long. It’s fuc and it’s been fuc ever since 2008. SPY $220p 5/15
Sources:
  1. https://www.hartfordfunds.com/dam/en/docs/pub/whitepapers/CCWP045.pdf
  2. https://www.usnews.com/news/business/articles/2020-03-11/a-look-at-what-happens-when-stocks-enter-a-bear-market
  3. https://en.wikipedia.org/wiki/Early_1990s_recession
Credit where credit is due: Third chart and inspiration for this post is from Rodney E. Constable on YouTube. He’s a little dry, but he’s the former VP of an investment firm and seems to know his shit (but does not, at all, understand how to market himself online). Check him out and listen to his shit on 1.5x speed, makes it much more 🐻able.
Edit: The only part of this post geared towards predicting the future is the final part regarding the average length of bear markets. However, since JPOW and TrumpTheCuck are taking unprecedented action, who knows what could happen. I believe really long dated puts are pretty safe here, because I don't think the question is what direction we're headed, but rather how fast. The general sentiment I'm trying to convey is that based on the performance of other markets, this should not be that fucking surprising. Additionally, who knows what international implications this beervirus crash will lead to. '08 ultimately led to the collapse of Greece's economy (source: https://www.thebalance.com/what-is-the-greece-debt-crisis-3305525).
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2020.02.22 19:09 Bubbly-Concern Farmaci prodotti in gran parte dalla Cina


PRENDETE QUESTO POST COME UNA SPECULAZIONE ASSOLUTA IN BACHECA PRINCIPALE.
Si tratta solamente di voci rese disponibili alla community italiana (noi non censuriamo niente), nel caso fosse interessata a fare ragionamenti in merito. Nessuno sta consigliando niente a nessuno e ogni azione o conclusione individuale è vostra unica e assoluta responsabilità.
Queste informazioni arrivano da fonti quarantinate e altamente controverse, ma ho controllato buona parte delle affermazioni e mi sembrano corrette. Non posso linkarvi la fonte o rischio il ban da reddit, ma se scrivete Nomecittàincriminata_flu troverete un sub completamente senza moderazione a 0 iscritti, non è detto che riusciate comunque a trovarlo e accedervi senza link diretto.


Senza perdersi in chiacchiere, questi farmaci sono prodotti al 90% in Cina. Ci sarà possibilmente da aspettarsi una carenza nel medio lungo termine, se la Cina stentasse ancora a lungo a rialzarsi.
Con estrema coscienza di causa, vi autosuggerite, esclusivamente per i farmaci "salva-vita", di comprarne una o due scatole in più per sicurezza, ben che vada lo userete lo stesso. Lasciate perdere antibiotici e molecole base da banco (aspirine, paracetamolo etc), gli impianti nel mondo si stanno già convertendo per produrli, ma se avete un trattamento cronico molto particolare avere una scatola in più non nuoce, lasciandone il giusto numero agli altri che come voi ne hanno bisogno per sopravvivere.
Molte di queste molecole della lista sono antibiotici base e antivirali base di cui non ci sarà carenza, ma ci sono anche farmaci secondari come antiipertensivi (ramipril), la lovastatina per il colesterolo e sopratutto neurolettici (se lasciate lo zio schizofrenico senza clorpromazina o lamictal è probabile vi faccia fuori lui prima del virus). Se prendete lo Xanax potete autosuggerirvi una visita dallo psichiatra e farvi prescrivere valide alternative, non vedo nella lista altre benzodiazepine quindi potete cambiare con delorazepam (en) e le altre 100 molecole analoghe (consultate lo psichiatra prima però eh mi raccomando).
Vi ho lasciato l'introduzione del post dell'autore originale in inglese così capite che queste molecole sono solo POSSIBILI CANDIDATI a una eventuale carenza nel mercato ed E' UNA SPECULAZIONE SUL MERCATO AMERICANO.
Ripeto comunque che si tratta solamente di voci rese disponibili alla community italiana (noi non censuriamo niente), nel caso fosse interessata a fare ragionamenti in merito. Nessuno sta consigliando niente a nessuno e ogni azione o conclusione individuale è vostra unica e assoluta responsabilità.


In the early 2000s, China's government subsidized drug production, undercutting American manufacturers. So these big US corporations simply laid off workers and shifted production to the East.
Johnson & Johnson cut close to 13k jobs, Pfizer laid off 2k researchers. GlaxoSmithKline has more than 2000 employees in China. All the big names are tied to China -- Roche, Novartis, Merck, Eli Lily and many more. So even if a big American drug company produces your meds, chances are good disruptions in the supply chain are going to cause problems.
Millions of Americans could experience significant delays in getting their prescription drugs.
And it's not just meds. China manufactures a number a drug related products like spray bottles or pumps. And some of the drugs aren't going to be manufactured elsewhere because China has exclusive manufacturing agreements for drugs for anesthesia, cancer and HIV/AIDS.
Those that can be made elsewhere require Active Pharmaceutical Ingredients (known as APIs). Even if you gear up factories in India, you still need the raw materials from China.
Here’s a list of medicines made in China, but any prescription drug may fall victim to shortages. These are simply the most likely candidates.
Aciclovir – (Zovirax) – antiviral drug
Advair – asthma medicine
Adrenaline Hcl – treatment for cardiac arrest
Albendazole – treatment for worms
Alfuzosin – (Uroxatral) treatment for enlarged prostate
Allopurinol – gout treatment
Alprazolam – (Xanax) – treatment for anxiety disorders
Amikacin sulfate – treatment for bacterial infections
Aminophyline -treatment for cerebral ischemia
Amiodarone Hydrochloride -treatment for irregular heartbeat
Amlodipine – treats high blood pressure & angina
Ampicillin – antibiotic
Amodiaquine – treatment of malaria
Amoxicillin – antibiotic
Aniracetam – (Draganon, Sarpul, Ampamet) a congnition enhancer
Artemether – treats drug resistant malaria
Artesunate – malaria treatment
Aspirin – anti-inflammatory painkiller
Artemether – treats malaria
Atenolol – high blood pressure medicine
Atropine – antidote against nerve agents
Avandia – (Avandia) treatment of diabetes
Budesonide – (Entocort) treatment of allergy & asthma
Bupropion (Wellbutrin) antidepressant
Calcifediol – treats vitamin D deficiency
Candesartan – (Blopress, Atacand, Amias, Ratacand) treats hypertension
Captopril – (Capoten, Inhibace) treatment for hypertension & congestive heart failure
Carbamazepine – treatment of epilepsy, ADD & ADHD
Carnosine – treatment for autism
Cefixime – antibiotic
Cefotaxime – (Claforan) antibiotic
Cefsulodin – also, cephalosporin – antibiotic
Cephealexin – (Keflex, Keftab) – antibiotic
Chloramphenicol – antibiotic
Chlorpheniramine Maleate – (Chlor-Trimeton, Piriton) Antihistamine
Chlorpromazine Hydrochloride
Chloroquine Phosphate – treatment of malaria
Cilexetil – (Atacand) treats high blood pressure
Cilostazole – (Pletal) treats peripheral vascular disease
Cimetidine – (Tagamet) – heartburn treatment
Ciprofloxacine – (Cipro) – antibiotic & one of two effective treatments for anthrax exposure
Clomiphene Citrate – (Clomid, Serophene, Milophene) infertility treatment
Clopidogrel Bisulfate – (Plavix) treats coronary artery disease
Co-trimoxazole – (Septrin, Bactrim) antibiotic
Cloxacillin – antibiotic
Coreg – (Coreg) beta blocker that treats congestive heart failure
Cromoglicate – treats allergies and asthma
Cyclosporine – immunosuppressive drug
Cytisine – (Tabex) smoking cessation drug
Dexamethasone Acetate – anti-inflammatory steroid
Diclofenac Sodium – (Flector patch/Voltaren) – anti-imflammatory painkiller used to treat arthritis, acute injury and menstrual pain
Diosmin – hemorrhoid treatment
Diphenhydramine hydrochloride – (Benadryl) antihistimine
Doxycycline Hcl – (Vibramycin) – antibiotic
Enalapril – (Renitec, Vasotec) treatment of hypertension, chronic heart failure
Enoxacin – (Enroxil, Penetrex) antibiotic
Erythromycin – antibiotic
Famotidine – (Pepcid) antacid
Ferrous Sulfate – treatment for iron-deficiency anemia
Flucloxacillin – (Flopen, Floxapen) antibiotic
Fluconazole – (Diflucan, Trican) antifungal drug
Furosemide – (Lasix) diuretic for treating congestive heart failure
Frusemide – diuretic used to treat heart failure & edema
Flucloxacillin sodium – antibiotic
Gentamycin – antibiotic
Glibenclamide (Diabeta, Flynase, Micronase) anti-diabetic drug
Gliclazide – diabetes treatment
Griseofulvin – antifungal drug
Glyceryl Trinitrate – treatment of angina & heart disease
Hydrochlorothiazide – (Aquazide H, Dichlotride, Microzide, Oretic) diuretic
Human growth hormone – treatment of growth failure in children
Ibuprofen – anti-inflammatory painkiller
Imitrex – (Imatrex) migraine medicine
Indomethazine – anti-inflammatory painkiller
Ketoconazole – (Nizoral) antifungal drug
Lincomycine – antibiotic
Lamictal – treatment for epilepsy & bipolar disorder
Letrozole – treatment of breast cancerLipitor – (Lipitor) lowers cholesteral
Loratadine (Claritin, Lomilan, Clarinase, Alavert, AllergyX) antihistamine
Lovastatin- lowers cholesteral
Lumefantrine – treatment of malaria
Mebendazole – (Ovex, Vermox, Antiox, Pripsen) treatment for worms
Mefenamic Acid – (Ponstel, Ponstan) non-steroidal, anti-inflammatory painkiller
Meloxicam – (Mobic) non-steroidal, anti-inflammatory painkiller
Metamizole sodium (Analgin, Dipyrone, Novalgin) painkiller, fever-reducer
Methyldopa – (Aldomet, Dopamet, Novomedopa) antihypertension drug
Metoclopramide – (Maxolon, Reglan, Degan, Maxeran, Primeran) anti-nausea drug
Metronidazole – treats infections
Moexipril – (Univasc) treatment of high blood pressure
Mycophenolate Mofetil – Immunosuppressive drug
Niclosamide – treats tapeworms
Nifedipine (Adalat, Nifedical, Procardia) treats hypertension, premature labor
Nitroglycerin – (Nitrospan, Nitrostat, Tridil) heart medication
Norfloxacin – antibiotic
Ofloxacin – (Floxin) antibiotic
Ondansetron – (Zofran) – nausea prevention for chemo patients
Orlistat – (Xenical) – obesity treatment
Oxandrolone – Synthetic anabolic steroid
Oxybutinin – treatment for incontinence
Oxymetholone – Synthetic anabolic steroid
Oxytetracycline – antibiotic
Paclitaxel – also taxol – cancer treatment
Paracetamol – also, acetaminophen – painkiller
Penicillin – antibiotic
Phenacetin – painkiller
Phenformin Hydrochloride – diabetes treatment
Prednisone – steroid
Promethazine Hydrochloride – (Phenergan, Romergan, Fargan, Avomine) antihistamine
Propranolol – (Inderal, Avlocardyl, Dociton, Inderalici, InnoPran XL) hypertension treatment
Pyrimethamine – (Daraprim) antimalarial drug
Propecia – (Propecia) for prostate enlargement and hair loss
Quinine – malaria treatment
Ramipril – used to treat hypertension and congestive heart failure
Ranitidine Hydrochloride – (Zantac) antacid
Ribavirin – (Copegus, Rebetol, Ribashere, Vilona, Virazole) anti-viral drug
Rifampicin+Isoniazid – malaria treatment
Ribavirin – (Copegus, Rebetol, Ribashere) antivirual drug
Rifampicin – antibiotic
Salbutamol – asthma, copd
Sibutramine – (Meridia) obesity treatment
Spironolactone – (Aldactone, Novo-Spiroton, Verospiron, Berlactone) diuretic
Streptomycin – antibiotic
Sucralfate – (Carafate) – treats ulcers & acid reflux disease
Sulfadiazine – antibiotic
Sulfamethoxazole – antibiotic
Sulfadoxine&Pyrimethamine – treatment for malaria
Sulpiride – (Meresa, Sulpirid Ratiopharm) treatment of schizophrenia
Tamoxifen – breast cancer treatment
Tinidazole – (Tindamax, Fasigyn) anti-parasitic drug
Trandolapril – treatment of high blood pressure
Trimethoprim – antibiotic
Valaciclovir – (Valtrex) antiviral drug
submitted by Bubbly-Concern to CoronaVirus_ITALIA [link] [comments]


2019.11.07 10:45 Darksideswife Still adjusting after emergency removal

Sketching short my fucked up weekend. (42, F, overweight)
Saturday night, I celebrated our 22 aniversary with steak & fries. Between 2:30 am and 6:30 am, I was wide awake by severe pain in top abdominal region, empty vomiting, and no meds helped (buscopans & colpermint). In the past, I felt similarly, but as they quiet down I never told my doctor about it. Who never feels a stomache ache in her life right?
But after 4 hours non stop terrible pain, I begged my hubs to drive me to ER, a drive from hell as I felt every turn and bump. Once there, I was given horse-sized painkillers, bloodwork and ultra-sound all in the space of two hours. Conclusion, a huge pile of stones and a slightly inflammed galbladder. They wheeled me at 10:30 am into OR for a keyhole surgery, three hours later neatly back in my room.
We’re four days further, the only pain I feel is an ache below my ribs each time I lie down on my right side or when I need to breathe deeply, cough or sneeze. But I take 2x voltaren (diclofenac 75 retard) for some comfort. Physically, it could be a lot worse. But mentally I’m a mess.
I’m freaking out about how to eat from now on. I’m following a low fat approach for 14 days on doct’s advice, white bread w light butter, lean chicken w potatoes, veggies, yoghurt and toast.
But I love chocolate, enjoy a burger king and pizza, and my biggest issue is that I cant size down my portions. I’m the one who eats the bigger burgers, one piece of chocolate is not small... I got overweight not by miracle.
I need to loose weight and I have zero discipline. On the other side, the risk of getting bigger health issues scares me like shit. If this galbladder removal wasnt a wake up call to change my habits, then I dont know what else will.
How do I balance this new life? To avoid binging attacks, that certainly will follow? Never again steak and fries? Sporadically, some bacon with breakfast? Or endure stomache ache and risk worse health problems?
Can you ingest anything prior to a fattier meal to facilitate the breakdown of fats? Not as a free card but when you don’t want to be the odd duck at family meals, everyones pity party? Or when the beast cant control herself and caves in?
How do you balance and hold on?
submitted by Darksideswife to gallbladders [link] [comments]


2019.05.07 14:34 Eladir Knee issue discomfort (orthopedic)

30 years old, male, 1.78m 5′10, 71kg 156lb, caucasian (Greek), duration of complaint ~6months.
I'm somewhat fit and eat healthy. My main physical activity for the last ~5 years was walking/jogging 4 days/week for 2.5-3 hours (15km).
6 months ago I was on a 10 day trip doing a lot of walking/hiking, like 6 hours per day (20km). In the 6th day my left (weaker in the sense I'm right handed) knee didn't feel normal, it wasn't something extreme but there was a little pain and when I fully extended it, it made a click. I was limping a bit so in the remaining 4 days I cut down the walking to half.
When I got back home it had already improved but I went to an orthopedic anyway. He took an x-ray, said that it showed no issue, it's probably "chondromalacia patellae", to RICE for a week, take it slowly after that and if the problem persisted after months, an MRI would be needed.
I followed his advice and it indeed got better, close to perfect but not 100%. Most of the time there's zero discomfort but sometimes when I'll attempt some weird "turning" move or after I've jogged for an hour, a very slight discomfort emerges. I've been cautious about it so I've reduced my activity to mostly walking 3 days/week for 2 hours (11km).
Reading a bit about it, I thought maybe it just takes time to fully fix but 6 months later I thought I should get an MRI. Here's the data I got in digital form (25mb), dunno if you'll be able to view them as they're in some weird format including a "Millensys Viewer" .exe. I also got a paper with the findings, it's in greek with medical vocabulary but I'll do my best translating it:
MRI LEFT KNEE JOINT
After checking on 3 levels, the following are observed:
Thinning regarding the posterior horn of the medial meniscus without any points of tear.
Normal intensity signal in the lateral meniscus, cruciate-lateral ligaments of the joint, quadriceps tendon, patellar ligament and vertical patellar ligaments.
Collection of synovial fluid, mainly in the area of ligaments and behind the patella.
Small chondropathy alterations in femoral condyles and the plateau tibials, both of which will be evaluated further rheumatologically.
Alterations of bone edema are not observed.
I'll plan an orthopedic visit to show him the MRI but a friend working in a hospital showed the above report to an orthopedic and based on just that he said it's pretty normal stuff, the fluid part being the important finding. He advised resting it for a week and taking voltaren retard 75 mg (diclofenac sodium) twice a day for 7 days in the short term and in the long term, doing specific exercises to strengthen my thigh muscles so as to provide more support to the knee.
Obviously it's not a major health issue, maybe people not exercising wouldn't even notice it but I want to get over it so I can return to exercising as I want to and I don't know what to do. Any advice ? Are the above recommendations reasonable ? Should I ignore the discomfort and train as I used to do ? Should I reduce walking for a time and do more stationary bike ? My main focus is aerobic exercise for the heart, the rest is secondary. I realise swimming is ideal in these situations and although I do swim semi-regularly in the summer, it's not a suitable substitute.
submitted by Eladir to AskDocs [link] [comments]


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submitted by Suzanne_Paxton to u/Suzanne_Paxton [link] [comments]


2018.05.23 10:56 New2TheMasterRace Likelihood of developing an upper GI bleed as a result of a one day drug interaction

Weight 122Kg Height 6' 2"
(Fat I know, but I carry a lot of muscle as well from being a Center in college)
Male Caucasian Gibraltar 20mg Daily dosage of Citalopram Gout
I am having a flair up of Gout, a particularly bad one. I usually take a strong NSAI and colchacine to combat it at the onset.
I have taken Diclofenac 150mg (Voltaren Retard) Diclofenaco Sodico. 24/1500mg Co-Codomol (I know that a bit too much paracetemol) 1.5mg Colchicina Seid (I think Seid is the lab)
I would usually take Omaprozol as well as a stomach liner. I have also not eaten anything because I am very queasy this morning.
My question is - As a one off day; what are the chances of developing an upper GI bleed due to not taking the stomach protector / not eating / taking a bit over the reccomended dosage of Diclofenac.
Ideally not looking for judgement; though will take the lecture if required.
submitted by New2TheMasterRace to AskDocs [link] [comments]


2018.03.28 11:44 re-patch Acromion/Clavicle inflammation, suggest exercises please

Hi everyone
To follow the rules, I've been to the doctor already and he said I have an inflammation/swelling at the acromion/clavicle area (the place where those two meet ...) sorry for the bad description, ENG is not my main language. I have received the doctors clearing to keep training, HOWEVER, he told me I am only allowed to do exercises which will not affect the shoulders. For the shoulders I should pause for 2 weeks (I got Voltaren Retard pills & some patches, which are helping with inflammations in general).
Usually I'm doing stuff like: skipping ropes, push-ups, sit-ups, squats, running, swimming, rope climbing, tricking (backflips etc.), slacklining, balance exercises etc.
I am now unsure of what kind of exercises I am allowed to do or not, especially my favorite ones: skipping ropes/sit-up variations/tricking (backflips/frontflips) for example. Can someone help me a bit here maybe? Would sit-ups/core exercises/skipping ropes pass as being easy on the shoulder or not?
Also, if you have some ideas for me, I'd be really happy to receive some exercises that should be fine to do in the next two weeks? Should I just stick to basic airsquats/running etc. and not use the shoulders at all? What would you do?
Thanks a lot for your help! cheers
submitted by re-patch to bodyweightfitness [link] [comments]


2018.02.10 22:17 peter_fretter Perle de la farmacie

Ce vor unii clienti la farmacie (perle din colectia unui farmacist):
  • Bună ziua….vreau şi eu o colega.
  • ???!!! De care colega?
  • Colega fixă… = Corega
Am cules treaba asta de pe Facebook, source is here. M-am stricat de ras si am zis sa fac un bine si comunitatii.
submitted by peter_fretter to Romania [link] [comments]


http://rodzice.org/