I think I am starting to see good changes! Almost no sweating in my hands & feet, which are the places where I drip sweat. Reduced sweating in armpits as well although this was not too big of an issue for me compared to my hand sweat. I really hope this medicine continues to show effects on my hyperhidrosis with minimal to no side effects! So far I haven’t noticed a huge difference in how I feel or noticed any of the listed side effects. I up my dosage today from 2.5mg once a day, to 2.5mg twice a day. One more step when I try 5mg once daily in about 3 weeks. I have struggled with this condition since I was very young. For as long as I can remember, sweat has impaired the ability to do certain activities with my hands. As I got older my feet started producing more sweat and most recently, my armpits started to sweat more. I will try to continue to share my experience as I have looked all over this group for remedies and relief from this very annoying and impairing condition. After reading a bit about oxybutynin on here, I bit the bullet coming home from work and picked up my prescription. Im not a fan of taking meds (or at least not ones that dont have mostly harmless natural ingredients) but I was very fed up with sweating and sage seemed to not work so I had to move on to try a stronger solution for myself. If anyone wants to share their experience taking oxybutynin feel free to, it would be greatly appreciated! Best wishes to everyone else struggling with this :)

I'm new to skyrim and modding in general but I read on load order is important that the game runs properly but I have no idea what or how to exactly sort it properly. Could anybody give a general guideline to follow. Currently whenever i encounter any problems i either do: a) Skip the mod entirely after searching the mods and found it might be too complex to follow b) Reinstall Skyrim and hope for the best c) Enable and disable mods to find out which is working or not working
Here's my plugin modlist if it helps
0 0 Skyrim.esm
1 1 Update.esm
2 2 Dawnguard.esm
3 3 HearthFires.esm
4 4 Dragonborn.esm
5 5 ccASVSSE001-ALMSIVI.esm
6 6 ccBGSSSE001-Fish.esm
254 FE 0 ccBGSSSE002-ExoticArrows.esl
254 FE 1 ccBGSSSE003-Zombies.esl
254 FE 2 ccBGSSSE004-RuinsEdge.esl
254 FE 3 ccBGSSSE005-Goldbrand.esl
254 FE 4 ccBGSSSE006-StendarsHammer.esl
254 FE 5 ccBGSSSE007-Chrysamere.esl
254 FE 6 ccBGSSSE010-PetDwarvenArmoredMudcrab.esl
254 FE 7 ccBGSSSE011-HrsArmrElvn.esl
254 FE 8 ccBGSSSE012-HrsArmrStl.esl
254 FE 9 ccBGSSSE014-SpellPack01.esl
254 FE a ccBGSSSE019-StaffofSheogorath.esl
254 FE b ccBGSSSE020-GrayCowl.esl
254 FE c ccBGSSSE021-LordsMail.esl
254 FE d ccMTYSSE001-KnightsOfTheNine.esl
254 FE e ccQDRSSE001-SurvivalMode.esl
7 7 ccTWBSSE001-PuzzleDungeon.esm
8 8 ccEEJSSE001-Hstead.esm
254 FE f ccQDRSSE002-Firewood.esl
254 FE 10 ccBGSSSE018-Shadowrend.esl
254 FE 11 ccBGSSSE035-PetNHound.esl
254 FE 12 ccFSVSSE001-Backpacks.esl
254 FE 13 ccEEJSSE002-Tower.esl
254 FE 14 ccEDHSSE001-NorJewel.esl
254 FE 15 ccVSVSSE002-Pets.esl
254 FE 16 ccBGSSSE037-Curios.esl
254 FE 17 ccBGSSSE034-MntUni.esl
254 FE 18 ccBGSSSE045-Hasedoki.esl
254 FE 19 ccBGSSSE008-Wraithguard.esl
254 FE 1a ccBGSSSE036-PetBWolf.esl
254 FE 1b ccFFBSSE001-ImperialDragon.esl
254 FE 1c ccMTYSSE002-VE.esl
254 FE 1d ccBGSSSE043-CrossElv.esl
254 FE 1e ccVSVSSE001-Winter.esl
254 FE 1f ccEEJSSE003-Hollow.esl
9 9 ccBGSSSE016-Umbra.esm
10 a ccBGSSSE031-AdvCyrus.esm
254 FE 20 ccBGSSSE038-BowofShadows.esl
254 FE 21 ccBGSSSE040-AdvObGobs.esl
254 FE 22 ccBGSSSE050-BA_Daedric.esl
254 FE 23 ccBGSSSE052-BA_Iron.esl
254 FE 24 ccBGSSSE054-BA_Orcish.esl
254 FE 25 ccBGSSSE058-BA_Steel.esl
254 FE 26 ccBGSSSE059-BA_Dragonplate.esl
254 FE 27 ccBGSSSE061-BA_Dwarven.esl
254 FE 28 ccPEWSSE002-ArmsOfChaos.esl
254 FE 29 ccBGSSSE041-NetchLeather.esl
254 FE 2a ccEDHSSE002-SplKntSet.esl
254 FE 2b ccBGSSSE064-BA_Elven.esl
254 FE 2c ccBGSSSE063-BA_Ebony.esl
254 FE 2d ccBGSSSE062-BA_DwarvenMail.esl
254 FE 2e ccBGSSSE060-BA_Dragonscale.esl
254 FE 2f ccBGSSSE056-BA_Silver.esl
254 FE 30 ccBGSSSE055-BA_OrcishScaled.esl
254 FE 31 ccBGSSSE053-BA_Leather.esl
254 FE 32 ccBGSSSE051-BA_DaedricMail.esl
254 FE 33 ccBGSSSE057-BA_Stalhrim.esl
254 FE 34 ccBGSSSE066-Staves.esl
11 b ccBGSSSE067-DaedInv.esm
254 FE 35 ccBGSSSE068-Bloodfall.esl
254 FE 36 ccBGSSSE069-Contest.esl
254 FE 37 ccVSVSSE003-NecroArts.esl
254 FE 38 ccVSVSSE004-BeAFarmer.esl
12 c ccBGSSSE025-AdvDSGS.esm
254 FE 39 ccFFBSSE002-CrossbowPack.esl
254 FE 3a ccBGSSSE013-Dawnfang.esl
254 FE 3b ccRMSSSE001-NecroHouse.esl
254 FE 3c ccEDHSSE003-Redguard.esl
254 FE 3d ccEEJSSE004-Hall.esl
13 d ccEEJSSE005-Cave.esm
254 FE 3e ccKRTSSE001_Altar.esl
254 FE 3f ccCBHSSE001-Gaunt.esl
14 e ccAFDSSE001-DweSanctuary.esm
254 FE 40 _ResourcePack.esl
Unofficial Skyrim Special Edition Patch.esp
unofficial skyrim creation club content patch.esl
LegacyoftheDragonborn.esm
Occ_Skyrim_Tamriel.esp
Campfire.esm
FlowerGirls SE.esm
TrueHUD.esl
SurvivalControlPanel.esp
Experience.esl
Schlongs of Skyrim - Core.esm
High Poly Head.esm
Expressive Facegen Morphs.esl
OCPA.esl
SkyUI_SE.esp
SMIM-SE-Merged-All.esp
Audio Overhaul Skyrim.esp
Relationship Dialogue Overhaul.esp
Immersive Jewelry.esp
AI Overhaul.esp
DungeonsRevisited.esp
Hand Placed Enemies.esp
Immersive Encounters.esp
Hothtrooper44_ArmorCompilation.esp
Point The Way.esp
0Kaidan.esp
Cloaks.esp
Immersive Weapons.esp
Summermyst - Enchantments of Skyrim.esp
Wildcat - Combat of Skyrim.esp
ImprovedCompanionsBoogaloo.esp
DBM_IW_Patch.esp
ElysiumEstate.esp
Schlongs of Skyrim.esp
SOS - Shop.esp
Occ_Skyrim-Legacy_of_Dragonborn_patch.esp
isilNarsil.esp
Hothtrooper44_Armor_Ecksstra.esp
LABikiniSSE.esp
icepenguinworldmapclassic.esp
Ars Metallica.esp
Cloaks - Dawnguard.esp
Cloaks - USSEP Patch.esp
My Home Is Your Home.esp
Fenrir Blades.esp
Bijin Warmaidens.esp
RichMerchantsSkyrim_x5.esp
The Huntsman.esp
UIExtensions.esp
RaceMenu.esp
XPMSE.esp
AddItemMenuSE.esp
RaceMenuPlugin.esp
FNIS.esp
DSerArcheryGameplayOverhaul.esp
UltimateCombat.esp
Sarta Sword.esp
VioLens SE.esp
DSerCombatGameplayOverhaul.esp
MithrodinSword.esp
Sarah Follower.esp
SOSRaceMenu.esp
CBBE.esp
RaceMenuMorphsCBBE.esp
NibeneanArmorsAndOutfit.esp
CL's Crissaegrim.esp
MCMHelper.esp
MovementMCO.esp
Lazy Weapon Pack.esp
TrueDirectionalMovement.esp
Precision.esp
AX KaidanArsenal.esp
BetterQuestObjectives.esp
BetterQuestObjectives - LOTD Patch.esp
AX KaidanArmory.esp
SmoothCam.esp
Lazy Weapon Pack 2.esp
ValhallaCombat.esp
Attack_MCO.esp
KatanaCrafting.esp
IA CBBE Patch.esp
ImperialStormcloakRangerSet.esp
12FemaleBrows.esp
Keytrace.esp
scar-adxp-patch.esp
I4IconAddon.esp
Arena.esp
HotKeySkill.esp
BowRapidCombo.esp
beltfastenedquivers.esp
Chesko_WearableLantern.esp
EnhancedAtronachs.esp
BetterThirdPersonSelection.esp
Alternate Dual Wield Weapon Speed.esp
Sojourn Over Signposts.esp
JaxonzMCMKicker.esp
ValhallaBackStabFix.esp
FPSBoost.esp
Insignificant Object Remover.esp
WaitYourTurn.esp
SkyrimReputation_SSE.esp
BuyStatsPerks.esp
Skyrim Reputation Improved.esp
Skyrim Reputation Patch.esp
AutomaticItemStorage.esp
Ursine Armour - Non HDT.esp
weight_usleep.esp
Armor of Intrigue.esp
UnreadBooksGlow.esp
TransmuteSoulGems.esp
SOS - Smurf Average Addon.esp
SOS - VectorPlexus Regular Addon.esp
[dint999] HairPack02.esp
Realistic AI Detection 3 - Medium Interior, Medium Exterior.esp
SlightlyFasterDaggers.esp
Book Of Shadows.esp
Nicos Reversed Daggers.esp
ObiWarpaintsTattoos.esp
ObiTattoos.esp
DBVO.esp
Hydra's Reversed Daggers.esp
BW Lydia.esp
LeftHandRings.esp
ImmersiveJewelryXSummermyst - Unrestricted.esp
DBM_UnreadBooksGlow_Patch.esp
DBM_ImmersiveJewelry_Patch.esp
DBM_CloaksofSkyrim_Patch.esp
DBM_SMIM_Patch.esp
AI Overhaul - RDO Updated Patch.esp
BW ifd Lydia patch.esp
IFDL_BijinAlt_Patch.esp
DBM_IA_Patch.esp
LydiaPatch.esp
LydiaPatchForLOTD.esp
zhenli 1.esp
AkaviriTsurugi.esp
OrcPonytailsForHumans.esp
loki_POISE.esp
KS Hairdo's.esp
OneClickPowerAttackMCM.esp
Immersive Citizens - AI Overhaul.esp
Convenient Horses.esp
Convenient Horses Anniversary Edition Patch.esp
Ordinator - Perks of Skyrim.esp
AutomaticItemStorage - Ordinator Patch.esp
Alternate Start - Live Another Life.esp
BetterQuestObjectives-AlternateStartPatch.esp
nwsFollowerFramework.esp
And here's the left panel modlist :
*DLC: HearthFires *DLC: Dragonborn *DLC: Dawnguard *Creation Club: ccVSVSSE004-BeAFarmer *Creation Club: ccVSVSSE003-NecroArts *Creation Club: ccVSVSSE002-Pets *Creation Club: ccVSVSSE001-Winter *Creation Club: ccTWBSSE001-PuzzleDungeon *Creation Club: ccRMSSSE001-NecroHouse *Creation Club: ccQDRSSE002-Firewood *Creation Club: ccQDRSSE001-SurvivalMode *Creation Club: ccPEWSSE002-ArmsOfChaos *Creation Club: ccMTYSSE002-VE *Creation Club: ccMTYSSE001-KnightsOfTheNine *Creation Club: ccKRTSSE001_Altar *Creation Club: ccFSVSSE001-Backpacks *Creation Club: ccFFBSSE002-CrossbowPack *Creation Club: ccFFBSSE001-ImperialDragon *Creation Club: ccEEJSSE005-Cave *Creation Club: ccEEJSSE004-Hall *Creation Club: ccEEJSSE003-Hollow *Creation Club: ccEEJSSE002-Tower *Creation Club: ccEEJSSE001-Hstead *Creation Club: ccEDHSSE003-Redguard *Creation Club: ccEDHSSE002-SplKntSet *Creation Club: ccEDHSSE001-NorJewel *Creation Club: ccCBHSSE001-Gaunt *Creation Club: ccBGSSSE069-Contest *Creation Club: ccBGSSSE068-Bloodfall *Creation Club: ccBGSSSE067-DaedInv *Creation Club: ccBGSSSE066-Staves *Creation Club: ccBGSSSE064-BA_Elven *Creation Club: ccBGSSSE063-BA_Ebony *Creation Club: ccBGSSSE062-BA_DwarvenMail *Creation Club: ccBGSSSE061-BA_Dwarven *Creation Club: ccBGSSSE060-BA_Dragonscale *Creation Club: ccBGSSSE059-BA_Dragonplate *Creation Club: ccBGSSSE058-BA_Steel *Creation Club: ccBGSSSE057-BA_Stalhrim *Creation Club: ccBGSSSE056-BA_Silver *Creation Club: ccBGSSSE055-BA_OrcishScaled *Creation Club: ccBGSSSE054-BA_Orcish *Creation Club: ccBGSSSE053-BA_Leather *Creation Club: ccBGSSSE052-BA_Iron *Creation Club: ccBGSSSE051-BA_DaedricMail *Creation Club: ccBGSSSE050-BA_Daedric *Creation Club: ccBGSSSE045-Hasedoki *Creation Club: ccBGSSSE043-CrossElv *Creation Club: ccBGSSSE041-NetchLeather *Creation Club: ccBGSSSE040-AdvObGobs *Creation Club: ccBGSSSE038-BowofShadows *Creation Club: ccBGSSSE037-Curios *Creation Club: ccBGSSSE036-PetBWolf *Creation Club: ccBGSSSE035-PetNHound *Creation Club: ccBGSSSE034-MntUni *Creation Club: ccBGSSSE031-AdvCyrus *Creation Club: ccBGSSSE025-AdvDSGS *Creation Club: ccBGSSSE021-LordsMail *Creation Club: ccBGSSSE020-GrayCowl *Creation Club: ccBGSSSE019-StaffofSheogorath *Creation Club: ccBGSSSE018-Shadowrend *Creation Club: ccBGSSSE016-Umbra *Creation Club: ccBGSSSE014-SpellPack01 *Creation Club: ccBGSSSE013-Dawnfang *Creation Club: ccBGSSSE012-HrsArmrStl *Creation Club: ccBGSSSE011-HrsArmrElvn *Creation Club: ccBGSSSE010-PetDwarvenArmoredMudcrab *Creation Club: ccBGSSSE008-Wraithguard *Creation Club: ccBGSSSE007-Chrysamere *Creation Club: ccBGSSSE006-StendarsHammer *Creation Club: ccBGSSSE005-Goldbrand *Creation Club: ccBGSSSE004-RuinsEdge *Creation Club: ccBGSSSE003-Zombies *Creation Club: ccBGSSSE002-ExoticArrows *Creation Club: ccBGSSSE001-Fish *Creation Club: ccASVSSE001-ALMSIVI *Creation Club: ccAFDSSE001-DweSanctuary *Creation Club: _ResourcePack -1.Bug & Game Patches_separator +- USSEP- Unofficial Skyrim Special Edition Patch +First Person Animation Teleport Bug Fix +- USCCCP -Unofficial Skyrim Creation Club Content Patches +Alternate Start - Live Another Life - SSE +SSE Display Tweaks +powerofthree's Tweaks +AddItemMenu - Ultimate Mod Explorer -2.Overhaul and UI_separator +SkyUI +Survival Control Panel +SkyUI Config Tweak - Equipped Items On Top SE +Dear Diary +Dear Diary DM and Paper (Squish) Fixes +Quest Journal Fixes +SkyUI - Survival Mode Integration +SkyUI SE - Difficulty Persistence Fix +Audio Overhaul for Skyrim (4.1.2) +Sound Record Distributor +JContainers SE +ConsoleUtilSSE NG +ConsoleUtilSSE +Dragonborn Voice Over +Dragonborn Voice Over (DBVO) - Plugin Replacer +Geralt DBVO Pack +Talion DBVO Voice Pack +Compass Navigation Overhaul +Infinity UI +UIExtensions +Convenient Horses +Summermyst - Enchantments of Skyrim +Combat Gameplay Overhaul SE +Ultimate Combat SE +Archery Gameplay Overhaul SE +Even Better Quest Objectives SE +SmoothCam +SmoothCam - Modern Camera Preset +MCM Helper +Jaxonz MCM Kicker SE +TrueHUD - HUD Additions +Address Library for SKSE Plugins +Relationship Dialogue Overhaul - RDO SE +AI Overhaul SSE +Ordinator - Perks of Skyrim +RaceMenu +Racemenu Patch GOG +PapyrusUtil SE - Modders Scripting Utility Functions +Wildcat - Combat of Skyrim +A Quality World Map +Attack MCO-DXP +VioLens - A Killmove Mod SE +Movement MCO-DXP +Precision +Raven's Awareness - AC-Valhalla inspired TrueHud color preset +Arena - An Encounter Zone Overhaul +Hand Placed Enemies - More populated spawns dungeons and POIs +Immersive Citizens - AI Overhaul +POISE - Stagger Overhaul SKSE +POISE - Stagger Overhaul - NG +Wait Your Turn - Enemy Circling Behaviour +Nether's Follower Framework +Project New Reign - Nemesis Unlimited Behavior Engine -3.Mission & Quest Mods_separator -4.Environmental Mods_separator -5.Cities,Town Add Ons_separator -6.Building Add Ons ( Within Cities )_separator -7.Plant & Foliage Mods_separator -8.Gameplay Changes & Tweaks_separator +Valhalla Combat +True Directional Movement - Modernized Third Person Gameplay +Campfire - Complete Camping System (Supports Skyrim VR) +-CBBE- Caliente's Beautiful Bodies Enhancer +XP32 Maximum Skeleton Special Extended +XP32 Maximum Skeleton Special Extended - Fixed Scripts +Schlongs of Skyrim SE +Fair Skin Complexion +Flower Girls SE and VR +Better MessageBox Controls +Rich Skyrim Merchants +Experience +Bow Rapid Combo V3 +Compatibility Patch for Archery Gameplay Overhaul (AGO) and XP32 Skeleton Styles MCM +One Click Power Attack MCM +One Click Power Attack NG -9.Animations_separator -Open Animation Replacer -Vanargand Animations - Sword Dual Wield Moveset MCO - SkySA -Vanargand Animations - Dual Wield Normal and Power Attacks -Vanargand Animations - Dual Wield Sneak Thrusts -Vanargand Animations - Dual Wield Sneak Strikes -Vanargand Animations - Archery -Dual Wield Sword MCO Moveset -Borgut1337's Dual Wield Parrying Non-SKSE Random Attacks (Oldrim conversion) -Elder Creed - Odyssey Dual Wield Dagger Moveset -Dual Wielding Unlocker -Elden RIM x DS3 Mashup I Dual wield katana moveset (MCO I SCAR) -ER Dual Wield Sword (MCO) -Vanargand Animations - Sneak idle walk and run -MCO - ADXP - Elder Creed - Blade -3rd Person Dual Wield Animation Fix SSE -Extra Drawing Animations -Disable Turn Animation SE I AE -Paired Animation Improvements -Animation Queue Fix -Animation Motion Revolution -Dynamic Activation Key -Immersive Interactions - Animated Actions -Open Animation Replacer - IED Conditions -Payload Interpreter -10.Texture Mods_separator +Cloaks of Skyrim SSE +Immersive Weapons +Bijin Warmaidens SE +Fenrir Blades +Sarta - Leather Wrapped Sword +Lazy Weapon Pack +Lazy Weapon Pack 2 +CL's Crissaegrim +Isilmeriel LOTR Weapons Collection SSE +Katana Crafting - SE +Mithrodin Sword +The Huntsman SE +Nibenean Armors and Outfit SE - UNP - UNPB - CBBE by Xtudo +Immersive Armors +Immersive Armours - SSE CBBE 3BA BodySlide +Imperial or Stormcloak Ranger Set SE +Kaidan's Arsenal +Kaidan 2 +Sithis Armour - Special Edition +Kaidan's Armory Samurai for HIMBO +Kaidan's Armory +BodySlide and Outfit Studio +Legendary Armors - Bikini SSE Beta +The Bathsheba Body (BSB) +Sarah - My character as a follower SE by Xtudo +Cleaned and Modernized Keybinds - Controlmap.txt +SCAR - Skyrim Combos AI Revolution +SCAR AE Support -Weapon Styles - DrawSheathe Animations for IED +Immersive Equipment Displays +Hot Key Skill +Dynamic Bow Animation +Dynamic Key Action Framework NG +dTry's Key Utils +dTry Plugin Updates +Inventory Interface Information Injector +Belt-Fastened Quivers +Better Jumping SE +Spell Perk Item Distributor +Enhanced Atronachs - With Levelling and Luminosity +Enemy (R)Evolution of Skyrim - EEOS +Wearable Lanterns +Dungeons - Revisited +Better Third Person Selection - BTPS +Immersive World Encounters SE +Elysium Estate SSE +Point The Way +Sojourn Over Signposts - Witcher-Style Fast Travel Alternative +Alternate Dual Wield Weapon Speed +Valhalla Combat - Backstab Bug Fix +Trainwreck - A Crash Logger +Backported Extended ESL Support +powerofthree's Papyrus Extender +eFPS - Exterior FPS boost +eFPS - Official Patch Hub +Low Resolution Particles +Insignificant Object Remover +SSE Engine Fixes (skse64 plugin) +Papyrus Tweaks NG +Skyrim Priority SE AE - CPU Performance FPS Optimizer +My Home is Your Home +Ars Metallica - Smithing Enhancement +Sovngarde - A Nordic Font +Skyrim Reputation +Skyrim Reputation - Fixed and Patched +Skyrim Reputation Improved +Buy Stats and Perks +Automatic Item Storage +AutomaticItemStorage - Ordinator Patch +Reduced weight of Ingredients and Potions +Armor of Intrigue SE +Grandmaster Ursine Armour - Special Edition +Behavior Data Injector Universal Support +Unread Books Glow SSE +Experience - MCM +Legacy of the Dragonborn +Legacy of the Dragonborn Patches (Official) +Security Overhaul SKSE - Lock Variations +Transmute Soul Gem +Book Of Shadows - Behaviour Based Stealth Additions +Realistic AI Detection (RAID) +Nicos Reversed Daggers +Reversed Daggers Moveset for MCO +Hydra's Reversed Daggers +Hydra's Reversed Daggers Keyword patch for MCO Reversed Daggers Moveset +Slightly Faster Daggers +Fuz Ro D-oh - Silent Voice +High Poly Head SE +Obi's Warpaints 2K +Obi's Tattoos 3BA 4K +Hairpack +Tempered Skins for Males - Nude Version +Tryael - The True Nord - Male Nord Preset +Ragnar and Brenna - Nord Presets for Racemenu +Immersive Jewelry SSE +Static Mesh Improvement Mod +Dialogue Interface ReShaped +Sarah as Lydia - Improved Follower Dialogue - Lydia patch +Lydia - Private Version - High Poly Head +Lydia Private Version +Improved Follower Dialogue - Lydia +Expressive Facial Animation -Female Edition- +Expressive Facegen Morphs SE +Bijin Warmaidens Patch Improved Follower Dialogue Lydia +Akaviri Tsurugi +Su Zhen li Two weapons +Left Hand Rings Modified SE +Bug Fixes SSE +Summermyst X Immersive Jewelry +AI Overhaul SSE - Official Patch Hub +Wearable Lanterns MCM Fixed No DLL Error +Dear Diary Paper Anniversary Edition Main Menu Patch +KS Hairdos SSE +Orc Shaved Ponytails for Humans SE +Nemesis Animation +Papyrus Ini Manipulator +Behavior Data Injector

I just keep replaying the whole thing in my head and everyone else’s reactions and I still don’t know if I did the right thing. Did I do too much? Not enough? I’m hoping maybe some parents in here that work in healthcare can give me an unbiased answer.
So daughter is 4 (turning 5 in June). She was diagnosed at birth with septo optic dysplasia and optic nerve hypoplasia. Long story short, she has very low vision and developmental and verbal delays. She is otherwise healthy as a horse, active, very strong, followed by specialists at a children’s hospital nearby, gets therapy through school, all that good stuff. We’ve never had issues with allergies, she’s been stung by a wasp (barely phased her), eats peanut butter, has had cooked egg and stuff made with egg and no issues. So this was alarming to say the least.
We live out in the country and have chickens so there’s no shortage of eggs that are laid out around my kitchen on a daily basis (obviously not anymore). About a month ago she grabbed one off the counter, broke it, and got egg all over her arms and hands and some on her face. I didn’t think much of it, it had happened before plenty of times. I cleaned her up, wiped up the floor and went on making dinner. She went and played in her room and when she walked back out I noticed she had little bumps popping up on her face and arms where the egg got on her. She didn’t seem bothered at all, I put some hydrocortisone cream on her, gave her a dose of Claritin just to be safe and it was cleared up in less than 10 minutes. I mentioned it to one of her teachers the next day at school and asked if they had ever noticed anything when they would have eggs for breakfast and they said no and told me they’d keep an eye out. And that was it. I didn’t think too much about it after that.
Fast forward to yesterday. Same scenario, I’m about to make lunch and she manages to grab an egg that I was sure was out of her reach, she dropped it, I immediately went over and checked her. It wasn’t even that much that got on her that I could tell. I got everything cleaned up and not even 5 minutes later her entire face is swollen, eyes swollen shut, bumps all over her legs and face. I am internally panicking at this point because it was so sudden and not something I ever expected to deal with. Plus we’re home alone and the nearest ER is at least 30 minutes away. There is a local clinic less than 5 minutes from our house so I called them, explained what was going on. Her face was swollen but she was still in good spirits, breathing fine, didn’t seem to be in distress. They told me to go ahead and bring her in. I just assumed the quicker I could get her to medical professionals, the better. I did consider calling for an ambulance but we’re in a rural area with one ambulance to service the entire county and I knew I could get her to the clinic faster than the ambulance could get to me. We get to the clinic, I’m filling out paperwork, nobody at the front really seems phased, they see her face but not really acting like it’s urgent. Nurse takes us back, gets her weight and height, gets history from me. She tried to get Daughter’s vitals but she has never tolerated any of that since infancy. Blood pressure cuffs send her into a full meltdown, she won’t keep a pulse ox on her finger. I always feel so bad for healthcare workers having to deal with her because as sweet as she is, she is EXTREMELY difficult at doctor visits. I can tell the nurse is getting frustrated with us. So then the NP comes in and looks at her and asks me, “So is there a reason why you didn’t just go to the ER?” My heart dropped and I tried to stay calm and told her I came here because it was a lot closer and I did call first and explain the situation and they said it was fine to come in. She then proceeded to tell me that they weren’t really equipped to handle anything like this and I should have just gone to the ER. I guess that was my first dumb mistake, assuming that a clinic with a full pharmacy attached could handle an allergic reaction. I just figured they’d give her a shot of Benadryl and we’d be good. But apparently not.
Other than the swelling and hives, Daughter wasn’t showing any other symptoms. The NP listened to her chest, said everything sounded good but she still wanted her to be monitored in case something happened and we’d be best off taking the ambulance to the ER. They gave her a dose of oral Benadryl and called the ambulance for us. Thirty minutes later the ambulance gets there, and we head to the ER. They were very kind and understanding, Daughter was actually having a good time riding in the ambulance, laughing and singing. She wouldn’t let them hook up any monitoring equipment still but they kept a close eye on her. I start feeling a little bad at this point because she’s still not in any distress and other than the severe facial swelling, seems totally fine, so I started feeling guilty for wasting local resources and peoples time.
We get to the ER and they get us to a bed and one of the nurses comes over and I can just tell right off the bat that she doesn’t even want us there. She was very short with us and kept talking at my daughter telling her that she’d have to leave if she didn’t act right. I kept mentioning that she was low vision and had verbal delays but I don’t know if she was listening. I was beyond stressed at this point and so was Daughter and she was admittedly being difficult yet again and not keeping the pulse ox on her finger. I just mentioned to the nurse that we have to go to the children’s hospital a lot and they’ve only ever managed to get her vitals once when she was sedated for an MRI. I guess at the time I was just trying to acknowledge that yes my kid is difficult and let the nurse know please don’t feel bad because she’s like this with everybody. I wasn’t trying to tell her how to do her job. She glared at me and snapped “I am NOT sedating your child just to get her vitals!” and stormed back over to the nurses station across from our bed and repeated the same thing loudly, “I am NOT sedating someone to get their vitals that’s just RIDICULOUS!!”
I’m trying not to break down and cry at this point. I feel like I should just apologize to everyone for wasting their time and leave. Like I’m that dumbass that went to the ER for no reason and took up space that a real emergency could have used. A different nurse came over and was very sweet. She used a different monitor that taped to her toe and we were able to get a quick reading just to verify that her stats were good. The doctor came in and listened to her heart and checked her out for any other symptoms. Said she seemed stable but he wanted to watch her for a couple of hours to make sure the Benadryl was working and she continued to improve. So after we hung out for an hour and watched PBS kids, her hives went away and her face cleared up and her eyes opened back up. The doctor came in and cleared her, pharmacy tech came in and brought us her Epipen prescription and gave us instructions on what to do next time (Benadryl, blue to sky, orange to thigh, straight to ER). Paid $300 and went home.
Daughter is perfectly fine. I however am not. I barely slept last night between getting up to check on her and replaying the whole scenario in my head. Part of me feels like I didn’t do enough and the other part feels like I overreacted and wasted peoples time. I apologize for this being so long. It’s just all been so heavy on my mind and I needed to get it out and get another perspective on the whole situation. Much thanks to anyone that managed to read all of this.

Targeting specific areas of fat, like stubborn belly fat, is a common desire for many people trying to lose weight. While there are numerous weight loss supplements on the market claiming to target belly fat specifically, it's essential to approach them with caution and skepticism.
Here are some common ingredients found in weight loss supplements that are often marketed for targeting belly fat:

1. Caffeine: Stimulants like caffeine are believed to increase metabolism and promote fat burning. However, while caffeine may provide a temporary boost in energy and metabolism, its effects on long-term weight loss and belly fat reduction are limited.
2. Green Tea Extract: Green tea contains compounds like catechins and caffeine that are thought to enhance fat oxidation and promote weight loss. Some studies suggest that green tea extract may modestly reduce body weight and waist circumference, including belly fat, but results can vary.
3. Conjugated Linoleic Acid (CLA): CLA is a type of fatty acid found in meat and dairy products, as well as in supplement form. Some research suggests that CLA supplements may help reduce body fat, including belly fat, although the evidence is mixed and the effects may be modest.
4. Garcinia Cambogia: This tropical fruit extract is often marketed as a weight loss supplement. Some studies suggest that it may inhibit fat production and suppress appetite, but the evidence is limited and inconclusive.
5. Soluble Fiber: Fiber supplements like glucomannan are believed to promote feelings of fullness and reduce appetite, potentially aiding in weight loss. While increasing fiber intake through whole foods is generally beneficial, the evidence on the effectiveness of fiber supplements for belly fat reduction is limited.

It's important to note that no supplement can specifically target fat loss in one area of the body, such as the belly, without affecting overall body composition. Additionally, many weight loss supplements may come with potential side effects or interact with medications.
The most effective and sustainable approach to reducing belly fat and promoting overall weight loss is through a combination of healthy eating, regular exercise, adequate sleep, and stress management. Focus on consuming a balanced diet rich in whole foods, including plenty of fruits, vegetables, lean proteins, and whole grains, while minimizing processed foods, sugary beverages, and excessive calorie intake. Combine this with regular physical activity, including both cardiovascular exercise and strength training, to support fat loss and improve body composition over time. Always consult with a healthcare professional before starting any new supplement regimen, especially if you have underlying health conditions or are taking medications.

hi! i have a few scars on my arms from cat wrangling, etc, about four to five months old. they're fairly flat but slightly shiny/textured and noticeably pigmented. i'm trying to get them to fade and blend in with the rest of my skin.
currently i'm using tretinoin and mederma scar gel. i have a tube of prescription .05% tretinoin cream left over from when i had terrible acne as a teen, so i apply that at night with a little aquaphor ointment on top. then in the morning i put on the mederma scar gel. its active ingredient is .05% allantoin. i then apply some sunscreen (spf 100) because i know tretinoin can cause sun sensitivity.
does anyone have any suggestions for my routine? i looked through this sub and saw most people were recommending silicone sheets over mederma, but those are even more expensive, and i'm afraid they wouldn't do anything now that the wounds are fully healed. i'm also not sure about the tretinoin, as it's at least two years out of date. will it still be effective? is it okay to use tretinoin with allantoin or will using both cause irritation/make things worse? i don't know that much about skincare, so any help is appreciated, lol

Gas separation can be done by using a variety of membranes such as polymeric membranes, mixed membranes, silica membranes, microporous membranes, zeolite membranes, and others. Gas separation based on membranes provides several advantages such as low costs involved in operation and maintenance, user-friendly approach, and lower energy consumption. Membrane-based gas separation system uses the difference in permeability of gas molecules passing through the membrane material, to separate the gases from each other. Gas separation techniques are widely adopted in oil refinery and gas production industries for applications such as dehydration of natural gas, carbon dioxide removal, and production of liquid nitrogen. The pharmaceutical industry is focused on development of novel methods for separation processes to reduce the costs involved in active ingredient manufacturing. Gas separation membranes are used in the pharmaceutical industry to separate oxygen gas for medical purposes.
The global Polymeric Membrane for Separation market was estimated at 768.29 Million USD in 2021 with CAGR 6.21% during 2021-2030. The objective of report is to define, segment, and project the market on the basis of product type, application, and region, and to describe the content about the factors influencing market dynamics, policy, economic, technology and market entry etc.
The report includes market size, upstream situation, market segmentation, market segmentation, price & cost and industry environment. In addition, the report outlines the factors driving industry growth and the description of market channels. The report begins from overview of industrial chain structure, and describes the upstream. Besides, the report analyses market size and forecast in different geographies, type and end-use segment, in addition, the report introduces market competition overview among the major companies and companies profiles, besides, market price and channel features are covered in the report.
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Based on Materials, the report describes major products type share of regional market. Products mentioned as follows:
Polyimide & Polyaramide Type Polysulfone Type Cellulose Acetate Type Others
Leading vendors in the market are included based on profile, business performance etc. Vendors mentioned as follows:
Air Products Air Liquide UBE Grasys Evonik Schlumberger IGS Honeywell MTR Borsig Parker Hannifin Tianbang SSS
Based on Application, the report describes major application share of regional market. Application mentioned as follows:
Isolation of Inert N2 from Air H2 Recovery CO2 Removal from Natural Gas VapoNitrogen Separation Others
Based on region, the report describes major regions market by products and application. Regions mentioned as follows:
Asia-Pacific North America Europe South America Middle East & Africa

In a recent study, researchers have successfully fabricatedinterpenetrating biopolymer network (IPN) membranes from natural compounds, agarose and natural rubber latex, without the use of toxic cross-linking agents. This breakthrough technology offers a promising solution for the separation of molecular species in harsh organic media, benefiting various industries such as petrochemical, biorefining, paint, pharmaceutical, and food.
Key Features of the Biopolymer Membranes
The biopolymer membranes exhibit excellent solvent resistance and tunable molecular sieving, making them suitable for a wide range of applications. The membranes are biodegradable, ensuring an environmentally friendly end-of-life phase. The use of natural materials and water as a solvent during fabrication reduces the environmental impact of the production process. Additionally, the membranes demonstrate high mechanical strength, thermal stability, and resistance to fouling, making them suitable for long-term operation in harsh environments.
Fabrication and Characterization of the Membranes
The IPN membranes were fabricated by combining agarose and natural rubber latex through a self-assembly and self-cross-linking process. The morphology and chemical information of the membranes were characterized using various techniques, including scanning electron microscopy (SEM), atomic force microscopy (AFM), and nano-Fourier transform infrared (nano-FTIR) spectroscopy. The results revealed a textured dense microstructure with a water contact angle of 71° ± 1° and a roughness value of 138.75 nm. The membranes' surface chemistry was also analyzed using X-ray photoelectron spectroscopy (XPS), which showed a high concentration of hydroxyl and carboxyl groups, contributing to their hydrophilic nature.
Nanofiltration Performance and Biodegradability
The nanofiltration performance of the membranes was evaluated using a crossflow filtration system. The results showed a linear correlation between the pure solvent flux and the solubility parameter, indicating that the membranes can be used with optimum linear control over polar solvents. The membranes demonstrated long-term stability over 72 h of continuous crossflow nanofiltration at 20 bar. The biodegradability of the membranes was confirmed through enzymatic treatment, ensuring a sustainable end-of-life phase. The membranes' biodegradability was further evaluated using a soil burial test, which showed a significant reduction in membrane weight and molecular weight over a period of 6 months.
API Purification and Impurity Removal
The membranes were successfully used for the purification of an active pharmaceutical ingredient (API) and the removal of a carcinogenic impurity. The results showed that the membranes can effectively remove impurities below the threshold of toxicological concern, making them suitable for pharmaceutical applications. The membranes' ability to remove impurities was further evaluated using a range of analytical techniques, including high-performance liquid chromatography (HPLC) and mass spectrometry (MS).
Scalability and Industrial Applications
The scalability of the membrane fabrication process was evaluated using a pilot-scale setup. The results showed that the membranes can be fabricated on a large scale while maintaining their performance and properties. The membranes' potential for industrial applications was further evaluated through collaborations with industry partners, which showed promising results in the areas of petrochemical, biorefining, and pharmaceuticals.
The development of biopolymer membranes for OSN offers a sustainable solution for the separation of molecular species in harsh organic media. The use of natural materials, water as a solvent, and the biodegradability of the membranes reduce the environmental impact of the production process. The membranes' excellent solvent resistance, tunable molecular sieving, and long-term stability make them suitable for various industrial applications. This breakthrough technology has the potential to replace traditional fossil-based polymer materials, contributing to a more sustainable future.

As the world shifts towards a more sustainable future, industries are under increasing pressure to adopt environmentally friendly technologies. One area that has seen significant advancements in recent years is the development of biopolymer membranes for organic solvent nanofiltration (OSN). In this blog post, we'll explore the benefits of biopolymer membranes, their applications, and the potential for scalability in industrial settings.
What are Biopolymer Membranes?
Biopolymer membranes are a type of membrane made from natural polymers, such as agarose and natural rubber latex. These membranes are fabricated using interpenetrating polymer networks (IPN), which provide excellent mechanical strength and stability. The use of natural materials and water as a solvent during fabrication reduces the environmental impact of the production process.
The Benefits of Biopolymer Membranes
Biopolymer membranes offer several advantages over traditional fossil-based polymer materials. Firstly, they are biodegradable, ensuring an environmentally friendly end-of-life phase. Additionally, they demonstrate high mechanical strength, thermal stability, and resistance to fouling, making them suitable for long-term operation in harsh environments.
Applications of Biopolymer Membranes
Biopolymer membranes have a wide range of applications across various industries. In the pharmaceutical industry, they can be used for the purification of active pharmaceutical ingredients (APIs) and the removal of carcinogenic impurities. In petrochemical and biorefining applications, they can be used for the separation of molecular species in harsh organic media.
Scalability and Industrial Applications
One of the key advantages of biopolymer membranes is their scalability. The fabrication process can be easily scaled up to meet the demands of industrial applications. In fact, pilot-scale studies have shown that biopolymer membranes can be fabricated on a large scale while maintaining their performance and properties.
The Future of Sustainable Technology
The development of biopolymer membranes for OSN is a significant step towards a more sustainable future. As industries continue to adopt green solvents and sustainable technologies, the demand for biopolymer membranes is likely to increase. With their excellent performance, scalability, and biodegradability, biopolymer membranes are poised to revolutionize the field of organic solvent nanofiltration.
biopolymer membranes offer a sustainable solution for the separation of molecular species in harsh organic media. Their excellent performance, scalability, and biodegradability make them an attractive option for industries looking to adopt sustainable technologies. As the world continues to shift towards a more sustainable future, biopolymer membranes are likely to play a key role in shaping the future of organic solvent nanofiltration.
Key Takeaways

• Biopolymer membranes are a sustainable solution for organic solvent nanofiltration
• They offer excellent performance, scalability, and biodegradability
• Applications include pharmaceutical, petrochemical, and biorefining industries
• The development of biopolymer membranes is a significant step towards a more sustainable future

This analysis also comes from Cults and Nonconventional Religious Groups: A Collection of Outstanding Dissertations and Monographs, "Shakubuku: A Study of the Nichiren Shoshu Buddhist Movement in America, 1960-1975", David A. Snow, 1993, pp. 175-177 - it's a section within the analysis here about how the SGI's "discussion meetings" were carefully planned and choreographed sales pitch performances aimed at convincing any "guests" to convert. I thought this part about the carefully structured "experiences" deserved its own post:

In addition to the general supportive role, members are provided with instructions regarding the more specific role activity. That is, they are coached as to how to give explanations of what NSA [former name of SGI-USA] is all about, to lead songs, and to give testimonies. Regarding the latter, for example, members are reminded to respond to the emcee's request for experiences with great alacrity and enthusiasm by thrusting their hands in the air in a vigorous manner and yelling out "hi."

Actually, it's "Hai!", which means "Yes/Okay/I'll do it" in Japanese.

And if called upon, they are reminded to attend to the five major points or the "five S's" of giving a good experience.

That "coaching" is done before the live performance at the "discussion meeting", of course, not reminded within that performance context. That would break the illusion, as you can imagine.

The first point is Shakubuku. Remember, the guests have absolutely no understanding of this practice or any NSA terminology. Always talk to the guests and not to the members. The sole purpose of an experience is to make the guests curious enough to join ... Don't use Buddhist terms and names the guests won't understand...
Point number two is story. Make sure an experience is just that - something which happened to you and which you either changed into a benefit or changed an aspect of your life-condition through chanting. Basically , an experience should be structured as
(a) I had a problem or I was satisfied [sic] with my life and

That's obviously a typo; it should be either "I wasn't satisfied with my life" or "I was dissatisfied with my life", as confirmed by part (b):

(b) then I chanted, solved the problem or changed that aspect of my life which I wasn't satisfied with...
Make sure that you stress that chanting was the ingredient which changed those aspects of your life. Otherwise, the guests won't be able to connect just how chanting and a person's problems relate.
The third point to keep in mind is simplicity. Make each point of the story simple and to the point. Don't clutter the issue with unnecessary details. Try to be as brief as possible.
The fourth point is that of a seeking mind. What this means is that the person giving an experience should try to find out what type of experience the leader wants to have conveyed to the guests that will most benefit them.

Clearly, this is all about crafting the most persuasive sales pitch, not about honestly and authentically communicating anything real.

We're not saying that there is a "one" type of experience that is sought, but experiences have to be geared to the guests at the meeting. A middle-aged person is definitely going to have hard time relating to the change in values of a college student... The point is, make sure you are perceptive enough to give the type of experience which the guests at the meeting can relate to best.

Keeping in mind that no one knows for certain WHO these "guests" will be - this sort of "adjustment" in the details has to be made on the fly, which demonstrates the inauthenticity of the "experience" performance. But the culties are supposed to make it appear "authentic":

The final point is one of the most important - sincerity ... Even if your experience isn't that spectacular or full of content, the guests can relate to a person' [sic] sincere way of giving the experience...

The "5 S's" section is footnoted as coming from:

"The Five S's of Giving a Good Experience," World Tribune (September 11, 1974). Also, see the NSA Quarterly (Winter, 1975), p. 13; and the World Tribune (October 25, 1974).

It was obviously a structured thing that was explicitly taught (indoctrinated).

These five pointers on how to construct and give a "good" experience are mentioned repeatedly in the movement's literature and by its leaders. Furthermore, members can learn how to construct testimonies in accordance with these instructions by simply watching and listening to other members, and especially core converts, when giving their respective experiences.

You can probably surmise that after a while, these "experiences" will all start to show the same standardized structure; this will be accepted within the cult (because that's the goal), but the guests won't realize just how structured it is - and the focus on making it as manipulative as possible.

Indeed, rank-and-file members and new converts are often told to watch and listen to how so-and-so gives an experience.

That's true - I remember that.

It should thus come as no surprise that the testimonies given at these meetings, or wherever, are usually structured in accordance with the above pointers or instructions. And when they are not, the violators are usually pulled aside after the meeting and provided with corrective suggestions. At the end of several meetings, for example, I overheard the district chief reprimanding and re-instructing members regarding the unsuitable testimonies they had given earlier in the evening. This sanctioning and corrective work occurs not only when unsatisfactory testimonies are given but whenever meeting or movement-related roles are performed in an unsatisfactory manner and whenever members visibly engage in conduct that is inappropriate from the standpoint of NSA. During the San Diego Convention weekend, for example, I observed on several occasions members who were being brought back into line for engaging in unbecoming conduct, such as smoking grass on the bus while en route to the convention. That members who conduct themselves and perform their roles in an unsuitable and unconvincing manner are frequently pulled aside and provided with corrective guidance thus suggests a third consideration pointing to the highly orchestrated and theatrical character of discussion meetings in particular and of NSA in general.

Everyone must be "on" at all times; they must at all times display the SGI-defined image that SGI believes will impress the public and be most appealing to draw in potential new members.
While these specific "five S's" aren't around any more, there are still guidelines for how to give an "experience":

How do I write an experience for SGI budhist meeting?
State the difficulty you faced.
State how long you have been struggling with it, and how it affected you.
State what you did to resolve it, and how much you chanted.
State the resolution, and what that means to you.
Keep it to under 3.5 minutes.
Before you give your experience, read it to someone who cares about you, someone you know, and ask for an honest opinion on how your delivery is. from 7 years ago

REHEARSE it, in other words. These "experiences" are NOT spontaneous!

In the world of nanotechnology, the art of assembly is a delicate dance of molecules and reactions. It is a process that requires precision, patience, and a deep understanding of the intricate relationships between building blocks. In this essay, we will delve into the step-by-step process of crafting PMPC25-PDPA70 polymersomes, a complex nanostructure with unique properties.
The journey begins with the selection of two key ingredients: MPC (2-Methacryloyloxyethyl phosphorylcholine) and DPA (Dopamine acrylamide). These molecules are the foundation upon which the polymersome is built, each with its own unique characteristics. MPC, with its water-loving head and water-repelling tail, provides a hydrophilic-hydrophobic balance that is essential for the polymersome’s structure. DPA, on the other hand, is the dopamine-inspired component that confers adhesive and reactive properties to the polymersome.
The next step is the linking of these molecules together in a chain, a process known as Atom-Transfer Radical Polymerization (ATRP). This sophisticated technique is akin to building a Lego structure with specific instructions, where each molecule is carefully added to the growing chain. The initiator molecule kicks off the chain-building process, while copper bromide and bipyridine act as catalysts, speeding up the reaction and ensuring its smooth progression.
As the reaction unfolds, the researchers carefully monitor its progress, using Nuclear Magnetic Resonance (NMR) spectroscopy to confirm that all the MPC has been incorporated into the growing chain. This is akin to taking a snapshot to see how the Lego structure is coming along, ensuring that each piece is in its correct place.
Once the MPC is used up, the researchers add more DPA to the mix, continuing the chain-building process and incorporating the dopamine-inspired component. The resulting mixture is then filtered through silica gel, removing impurities and leaving behind a pure solution. This solution is then subjected to dialysis, a process that removes smaller molecules, and finally, freeze-dried to produce a fluffy powder of PMPC25-PDPA70 polymer.
But the journey is not yet complete. The researchers must still verify the quality of the polymer, using techniques such as Gel Permeation Chromatography (GPC) to separate the polymer chains by size. This analysis is akin to running a race, where smaller chains move faster, while larger chains lag behind. The results confirm the polymer’s characteristics, ensuring that it meets the required standards.
The final step is the creation of the polymersomes themselves, a process known as self-assembly. The polymer powder is dissolved, spread into a thin film, and then rehydrated to form tiny, bubble-like structures called polymersomes. Alternatively, the polymer can be dissolved in acidic conditions, and then the pH slowly raised, triggering the polymer molecules to self-assemble into polymersomes.

In the end, the art of assembly is a testament to human ingenuity and the power of science. By carefully crafting each step, the have created a complex nanostructure with unique properties, a true marvel of modern technology.researchers 

In the world of nanotechnology, the art of assembly is a delicate dance of molecules and reactions. It is a process that requires precision, patience, and a deep understanding of the intricate relationships between building blocks. In this essay, we will delve into the step-by-step process of crafting PMPC25-PDPA70 polymersomes, a complex nanostructure with unique properties.
The journey begins with the selection of two key ingredients: MPC (2-Methacryloyloxyethyl phosphorylcholine) and DPA (Dopamine acrylamide). These molecules are the foundation upon which the polymersome is built, each with its own unique characteristics. MPC, with its water-loving head and water-repelling tail, provides a hydrophilic-hydrophobic balance that is essential for the polymersome’s structure. DPA, on the other hand, is the dopamine-inspired component that confers adhesive and reactive properties to the polymersome.
The next step is the linking of these molecules together in a chain, a process known as Atom-Transfer Radical Polymerization (ATRP). This sophisticated technique is akin to building a Lego structure with specific instructions, where each molecule is carefully added to the growing chain. The initiator molecule kicks off the chain-building process, while copper bromide and bipyridine act as catalysts, speeding up the reaction and ensuring its smooth progression.
As the reaction unfolds, the researchers carefully monitor its progress, using Nuclear Magnetic Resonance (NMR) spectroscopy to confirm that all the MPC has been incorporated into the growing chain. This is akin to taking a snapshot to see how the Lego structure is coming along, ensuring that each piece is in its correct place.
Once the MPC is used up, the researchers add more DPA to the mix, continuing the chain-building process and incorporating the dopamine-inspired component. The resulting mixture is then filtered through silica gel, removing impurities and leaving behind a pure solution. This solution is then subjected to dialysis, a process that removes smaller molecules, and finally, freeze-dried to produce a fluffy powder of PMPC25-PDPA70 polymer.
But the journey is not yet complete. The researchers must still verify the quality of the polymer, using techniques such as Gel Permeation Chromatography (GPC) to separate the polymer chains by size. This analysis is akin to running a race, where smaller chains move faster, while larger chains lag behind. The results confirm the polymer’s characteristics, ensuring that it meets the required standards.
The final step is the creation of the polymersomes themselves, a process known as self-assembly. The polymer powder is dissolved, spread into a thin film, and then rehydrated to form tiny, bubble-like structures called polymersomes. Alternatively, the polymer can be dissolved in acidic conditions, and then the pH slowly raised, triggering the polymer molecules to self-assemble into polymersomes.

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ps://discord.com/invite/4pTtypfSvM
Visit today, Apply now - 24 hour max beta app wait time at the moment !!!

• Over 40 different legal jobs
• Player ownable mech shops, food stores etc
• Full PD with MDT/Radar (whitelisted)
• EMS with npc and player options, various hospitals (whitelisted)
• Banks
• Robberys
• ATM Hacking
• Money laundering
• Grow you own drugs
• Over 7 different strains
• various gang owneable drug activities
• over 400 custom tuned cars
• Play arcade games
• Phone with app store,games and more
• Pokemon TCG With badge and trophy system
• Npcs with daily events
• Seasonal content - halloween, christmas etc
• Hunting
• Farming
• Seed to plate ingredient systems and features
• Daily rewards and season pass
• and so much more !!!!

I was hired by a 3 Michelin Star restaurant as a Commis Chef (prep cook) and relocated across the country to do so. I've been here 7 months and it's been mostly hell. I've been screamed at in front of the whole kitchen by management, berated by other cooks, bullies, has things physically thrown onto my cutting board, been threatened with termination and more. I was supposed to get a relocation compensation, but HR said it was a "miscommunication". I'm treated like an idiot and all I do is measure ingredients and pick flowers.
I've had 3 work injuries since starting because I'm rushed to go fast in an unsafe way. Most recently I got Covid after management told a symptomatic, Covid positive employee to take his mask off because he thought they were faking. I sent HR a complaint and have been ignored. Every day is just one big anxiety attack and I'm missing work to the point it's hurting my reputation. Every kitchen I've interviewed with around here has only negative things to say about the restaurant and how they treat employees.
I recently was offered a job at another high end restaurant without any stars but with multiple James Beard Awards attached to it. I'd get more experience working on the line in a fast paced but high caliber environment. During my working interview I felt happier than almost any day I've been here and the people seem nicer and helpful. The restaurant itself is not as clean, but my current job actively hides violations from the health department. I asked my old mentor for advice and he recommended staying for a year, but even the thought of that scares me. I'm becoming a meaner more bitter person and I don't want to become that.
I came here to work at this restaurant and I don't want to deal with the bullshit anymore, but I don't want to fail the people who believe in me back home or view myself as a failure for leaving after 7 months. I know not all cooks have the opportunity to work at a 3 star restaurant and don't want to squander the opportunity, but at this point in my culinary career I have more experience picking flowers than working on the line and I feel it's a big gap in my education that this new job could fill and I'd feel better mentally as well. I don't want to make the wrong decision and any advice is greatly appreciated.

I was hired by a 3 Michelin Star restaurant as a Commis Chef (prep cook) and relocated across the country to do so. I've been here 7 months and it's been mostly hell. I've been screamed at in front of the whole kitchen by management, berated by other cooks, bullies, has things physically thrown onto my cutting board, been threatened with termination and more. I was supposed to get a relocation compensation, but HR said it was a "miscommunication". I'm treated like an idiot and all I do is measure ingredients and pick flowers.
I've had 3 work injuries since starting because I'm rushed to go fast in an unsafe way. Most recently I got Covid after management told a symptomatic, Covid positive employee to take his mask off because he thought they were faking. I sent HR a complaint and have been ignored. Every day is just one big anxiety attack and I'm missing work to the point it's hurting my reputation. Every kitchen I've interviewed with around here has only negative things to say about the restaurant and how they treat employees.
I recently was offered a job at another high end restaurant without any stars but with multiple James Beard Awards attached to it. I'd get more experience working on the line in a fast paced but high caliber environment. During my working interview I felt happier than almost any day I've been here and the people seem nicer and helpful. The restaurant itself is not as clean, but my current job actively hides violations from the health department. I asked my old mentor for advice and he recommended staying for a year, but even the thought of that scares me. I'm becoming a meaner more bitter person and I don't want to become that.
I came here to work at this restaurant and I don't want to deal with the bullshit anymore, but I don't want to fail the people who believe in me back home or view myself as a failure for leaving after 7 months. I know not all cooks have the opportunity to work at a 3 star restaurant and don't want to squander the opportunity, but at this point in my culinary career I have more experience picking flowers than working on the line and I feel it's a big gap in my education that this new job could fill and I'd feel better mentally as well. I don't want to make the wrong decision and any advice is greatly appreciated.