Bitcoin

• Amber_Sam

The State of Wisconsin Investment Board discloses buying $99 million worth of BlackRock's spot Bitcoin ETF - SEC FORM 13-F Information Table
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• FairBlamer

New Vanguard CEO Discussing His Bitcoin ETF Filing (While Leading ETF Business at BlackRock)
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• Cryptoconomy

The Model that Explains Why the World is Falling Apart...
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ethereum

• redrip52

Dai vs GHO vs crvUSD
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• Zfellows

HELP! Sent ETH from Coinbase to Polygon on GGpoker
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• binnsyboysg

Smart contract engineer looking for opportunities
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CryptoCurrency

• rizzobitcoin

LUNA crashing to $0 in 1 day, exactly 2 years ago. A lasting reminder of the risks of crypto ✨
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• ARoyaleWithCheese

Tornado Cash Developer Alexey Pertsev Sentenced to 64 Months in Prison by Dutch Court
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• Omn1Crypto

Jim Cramer Recommends Bitcoin Against MicroStrategy Shares, Advising To Purchase Directly ‘If You Want Bitcoin Exposure’
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btc

• rareinvoices

17 hours left until the BCH upgrade to adaptive block sizes, effectively solving the scaling debate, possibly forever. BCH has solved onchain scaling.
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• samdane7777

The Netherlands Verdict for Tornado
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• btcxio

*The Blocksize Wars are over with the Bitcoin Cash Adaptive Blocksize Limit Algorithm upgrade *
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SatoshiStreetBets

• Chineyo

Unlocking Real-Time Insights: The Magic you can create with Data
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• Hotsiam

$ETF ETHTrustFund $1.5m Treasury 900% APY Staking Yield Ethereum ETF Narrative Hype V2 Coming Soon [$90k Market Cap] [2.5 Months Old]
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• Token_Broker

OG memes meta is taking off
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CryptoMarkets

• Mattie_Kadlec

NiceHash To Host Bitcoin Conference In November
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• ProffesionalAds

XRP Price Eyes $0.55 as Ripple Files New Motion against SEC
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• reichardtcole

What are you investing more in right now?
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CryptoCurrencies

• RF12

El Salvador Launches Own Proof-of-Reserves Website to Track Its $360M Bitcoin Holdings
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CoinBase

• Shaver5000

Account Restricted
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• ArchitecTJ94

Nicely done, CoinBase support take slow response approach until my account closed. (So they don't have to offer service to closed account)
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• 1hour54minutes

*Coinbase closed my account without explanation and won't let me empty my wallets *
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binance

• AutoModerator

Binance Support Thread
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FantomFoundation

• DragonSlayerFX

Help wrapped btc
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solana

• m4r00o

Solchan’s One-Month Update
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• Ok_Cranberry_9653

*Roaring Kitty: GameStop Causes a Shift In Memecoin Meta. *
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• R100K-Martin-Lunger

Have you been investing in any solana memecoins?
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cosmosnetwork

• defiCosmos

Yieldmos is shutting down. 05/31/2024 and thats a wrap... They will be missed.
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• cameron_kavalabs

WBTC on Kava EVM is now LIVE on Binance! 🎉
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• catdotfish

👩🏻‍🚀👨🏽‍🚀 Cosmos Daily Discussion
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algorand

• omniwarp

It feels like the sentiment is finally turning
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• Independent-Care-353

LottoRace on Algorand Just Got Even Better with USDC Integration! 🚀
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• semanticweb

xGov Proposal 182 has reached 55% and need your support to take algorand to more web3 users.
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cardano

• kwhahn

We need to up our game
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• PALM-Economy

Palmyra Producer Wins Major Award
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• Mike_Hornan

The Governance Tree
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Monero

• Dopenxans

Reto is live now
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• Substantial-Ad3830

Life in nyc after localmonero
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• sk420_

baldeagle's proposal regarding P2P trading matrix room
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NFT

• feelingdrawsy

Porky Pixels Ordinals now LIVE at Ordzaar. Free to mint. 333 supply
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• surf_bluecrab

I am new here. I would like to promote my NFTs and my art websites
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• CreatorofArk

What kind of trader are you? Chicken panic seller or whale long term hodler?
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So, I recently ran into a lady who has opened a couple nail salons and is a rabid follower of Grant Cardone and his 10x program. I met her because I’m on the board for the chamber of commerce for my city, and she is one of our “ambassadors”.
While she herself is a true business owner, she has dropped so much money on his 10x university and is almost cult like in her fanaticism for his program. I’m a managing partner at a law firm, so I’m no stranger to owning and running a business, but holy shit does talking to her raise tons of red flags. Her businesses are being propped up by her husband’s generous starting capital of a million bucks, and while they have some potential, her business model is similar to a tech startup, huge injection, generate massive traction, and hope it works out… very little thought into execution, accounting, and financial planning.
She has dumped tons of money into the 10x thing and praises Grant as this Jesus figure who doesn’t need money and is spreading his gospel for the good of the people. While she’s great for promoting the chamber’s membership, my job as a board director is to gauge her to make sure she’s not pulling our Chamber members into any cult.
Anyone here have experience with Grant Cardone or his 10x system? Everything I look into tells me he’s the one of those financial “gurus” who isn’t giving bad advice per sẽ, but does sell massively overpriced “lessons” which give vague, repetitive, self-congratulatory lessons that don’t really add any value to the “student”.

Today, the SCU released the following statement:

The Scientific Coalition for UAP Studies (SCU) announces the addition of Dr. Laura Domine and Dr. Doug Buettner to the Board of Directors.

Adding these two board members will bring new rigor to the SCU goal of engaging academia to help answer long-standing and fundamental questions about the nature of UAP.”— Scientific Coalition for UAP Studies
WASHINGTON, DC, UNITED STATES, May 15, 2024 /EINPresswire.com/ -- Today, the Scientific Coalition for UAP Studies (SCU) released the following announcement:
The SCU is pleased to announce the addition of physicist Dr. Laura Domine and physicist and astronautical engineer Dr. Doug Buettner to the Board of Directors. These two academic researchers work on the scientific questions raised by UAP reports and supervise college students applying STEM principles to these studies. Adding these two board members will help to fortify our role as a national leader in promoting the rigorous scientific investigation of unidentified anomalous phenomena (UAP).
Dr. Laura Domine is a postdoctoral research fellow at the Center for Astrophysics, Harvard University. She completed her Ph.D. in physics at Stanford in 2023, working at the SLAC National Accelerator Laboratory operated by Stanford University. Dr. Domine worked on novel machine learning (ML) methods for liquid argon time projection chamber-based neutrino detectors such as ICARUS. In April 2023, she joined Harvard University’s Galileo Project to help design ML-based scalable experimental approaches to conducting scientific surveys of UAP.
Laura Domine: “I am excited to be living through a rare moment of opportunity to destigmatize the scientific study of the UAP phenomenon and to conduct open and foundational research related to this under-explored topic. As part of the Board, I want to support the SCU community’s efforts to establish academic UAP research as a logical and well-accepted area of scientific inquiry.”
Dr. Doug Buettner received his Ph.D. in astronautical engineering from the University of Southern California. Dr. Buettner is the Deputy Chief Scientist of the Acquisition Innovation Research Center - a multi-university applied research center led by the Stevens Institute of Technology. He has over 30 years of industry experience in aerospace and software-intensive systems engineering for the Department of Defense (DOD) and NASA. Dr. Buettner is also an adjunct professor in the University of Utah’s Mechanical Engineering Department’s Systems Engineering Program, teaching space mission engineering.
Doug Buettner: “Joining the SCU’s Board of Directors is an honor and a profound responsibility. Recognized as a preeminent international organization engaged in the scientific investigation of UAPs, I am eager to further contribute to SCU’s pioneering mission of expanding our understanding of this global phenomenon.”
Robert Powell, SCU Co-Founder and Executive Board Member: “The expertise and practices of academia are critical in addressing the scientific exploration of UAP. The open exchange of information is fundamental to the scientific process. Science relies on transparency, peer review, and the sharing of results to build upon existing knowledge, verify findings, and foster collaboration. The appointment of Dr. Domine and Dr. Buettner to the Board exemplifies SCU’s commitment to the scientific process.”
***
SCU promotes and encourages the rigorous scientific examination of UAP, commonly known as Unidentified Flying Objects (UFOs). SCU comprises scientists, engineers, members of the high-tech and defense industries, former military, and other professionals, utilizing scientific principles, methodologies, and practices to advance the study of UAP observed and reported around the globe.
The Scientific Coalition for UAP Studies is a 501(c)(3) charitable organization.
https://www.einpresswire.com/article/711752130/scu-announces-two-additions-to-the-board-of-directors

Hi all,
Just been promoted to the premier league, but haven’t received any promotion money or my budget for next season. I usually get an email saying ‘board initial budget’ but haven’t received one.
I’m on June 6th 2024 atm. Any help?
Thanks

Today, SCU released the following press release:
The Scientific Coalition for UAP Studies (SCU) announces the addition of Dr. Laura Domine and Dr. Doug Buettner to the Board of Directors.
Adding these two board members will bring new rigor to the SCU goal of engaging academia to help answer long-standing and fundamental questions about the nature of UAP.”— Scientific Coalition for UAP Studies
WASHINGTON, DC, UNITED STATES, May 15, 2024 /EINPresswire.com/ -- Today, the Scientific Coalition for UAP Studies (SCU) released the following announcement:
The SCU is pleased to announce the addition of physicist Dr. Laura Domine and physicist and astronautical engineer Dr. Doug Buettner to the Board of Directors. These two academic researchers work on the scientific questions raised by UAP reports and supervise college students applying STEM principles to these studies. Adding these two board members will help to fortify our role as a national leader in promoting the rigorous scientific investigation of unidentified anomalous phenomena (UAP).
Dr. Laura Domine is a postdoctoral research fellow at the Center for Astrophysics, Harvard University. She completed her Ph.D. in physics at Stanford in 2023, working at the SLAC National Accelerator Laboratory operated by Stanford University. Dr. Domine worked on novel machine learning (ML) methods for liquid argon time projection chamber-based neutrino detectors such as ICARUS. In April 2023, she joined Harvard University’s Galileo Project to help design ML-based scalable experimental approaches to conducting scientific surveys of UAP.
Laura Domine: “I am excited to be living through a rare moment of opportunity to destigmatize the scientific study of the UAP phenomenon and to conduct open and foundational research related to this under-explored topic. As part of the Board, I want to support the SCU community’s efforts to establish academic UAP research as a logical and well-accepted area of scientific inquiry.”
Dr. Doug Buettner received his Ph.D. in astronautical engineering from the University of Southern California. Dr. Buettner is the Deputy Chief Scientist of the Acquisition Innovation Research Center - a multi-university applied research center led by the Stevens Institute of Technology. He has over 30 years of industry experience in aerospace and software-intensive systems engineering for the Department of Defense (DOD) and NASA. Dr. Buettner is also an adjunct professor in the University of Utah’s Mechanical Engineering Department’s Systems Engineering Program, teaching space mission engineering.
Doug Buettner: “Joining the SCU’s Board of Directors is an honor and a profound responsibility. Recognized as a preeminent international organization engaged in the scientific investigation of UAPs, I am eager to further contribute to SCU’s pioneering mission of expanding our understanding of this global phenomenon.”
Robert Powell, SCU Co-Founder and Executive Board Member: “The expertise and practices of academia are critical in addressing the scientific exploration of UAP. The open exchange of information is fundamental to the scientific process. Science relies on transparency, peer review, and the sharing of results to build upon existing knowledge, verify findings, and foster collaboration. The appointment of Dr. Domine and Dr. Buettner to the Board exemplifies SCU’s commitment to the scientific process.”
***
SCU promotes and encourages the rigorous scientific examination of UAP, commonly known as Unidentified Flying Objects (UFOs). SCU comprises scientists, engineers, members of the high-tech and defense industries, former military, and other professionals, utilizing scientific principles, methodologies, and practices to advance the study of UAP observed and reported around the globe.
The Scientific Coalition for UAP Studies is a 501(c)(3) charitable organization.###
https://www.einpresswire.com/article/711752130/scu-announces-two-additions-to-the-board-of-directors

Hey, back to this platform after a long time and this is my first post since. I figured that this could potentially help me, considering how the culture here is a bit more practical and realistic than other social media. Well, this is going to be a bit long discussion/rant about my life since the last couple of years. A bit of background information about me: I was considered to be academically brilliant all of my life, except when the lockdown started, the down fall (or as people say) began. I was distracted, however still was enthusiastic about life. However, it all got sucked out eventually. At that time, negativity was all around and I got sucked in too, completely draining all my mental health and energy. It kinda worsened after I left my regular high school about two years ago and joined a non attending one. I recently graduated about a month ago, still waiting for the results. But hell, has it been a journey. Well, I would like to mention what potentially had a more negative impact on my mental health. So, it was all kinda like a scam, the non attending thing and stuff related. It was all due to a coaching institution, which got all the primary attention through social media, and which got me into that fraud school. I never fall into scams (online or real life) considering my technical skills and expertise, but this was more of a trap. All those fake promises did pile up, and eventually, I had to face so much of harassment when it came to the final year of my high school exams (we have board exams here, and it's nationally competitive). When things couldn't get any worse, I suffered from an ankle fracture right in the middle of my preparation period, had to leave coaching altogether and study all alone at home (it was all due to the poor engineering of the institute, others had noticed too). Even after some months when I was kinda able to walk, I was suggested to go back, however, for me it felt awkward and non welcoming for some reason, even if I knew we had to pay so much of money to them. I mean, they didn't even care to even ask how I was doing all this time, like literally, they were aware of everything that took place with me. All they sent was promotional texts. NO guide, NO mentor, NO social media, NO friends, had to study all alone and somehow still make it through to make sure that I am qualified more than enough for the university entrance tests. I probably even have undiagnosed ADHD. If you are wondering what was my entertainment sources, it was primarily gaming, and binging on TV shows especially comedy. Well, coming to the part of my board exams, there was so much of uncertainty involved in the whole thing that all of it was seriously messed up. So much of misinformation, miscommunication and a non cooperative environment. Comparing to other schools for the pracs that they completed all of it in a week, the scammers in my case, took literally two damn months for all of it (with breaks in between, but still of course, it requires a mental preparation, which significantly affected my studies). They literally fixed the last one ten days before the theoretical exams started. As much as they lied, it was held so far away from our residence, we had to stay at a hotel every single day before the exam, and reach the exam center from there, then come back home afterwards.
Of course, I missed out on all high school experiences, even if it's not as much as the US, rather way less. However, I am not really disappointed in that. I was rather tensed about my results, that got released, and wasn't the best for which my mood went to hell. I wanted to study abroad, but this has been seriously traumatizing and I am totally unsure of what to do, currently thinking about taking the standardized tests and trying to research more about other requirements, all alone. I know that this post is related to career guidance and I will be posting the same there too, just wanted to share my story, which is not a part of the future decisions.
NOTE - This is a pretty serious discussion, if you are a troll or someone who likes to act like one, you better stay out of this. I am not in the mood.

(Flagging as ELI5 because I need help approaching this to people with limited English skills.)
I work for an Asian culture non-profit that throws a yearly festival in my city. We've been invited, along with the organizers of other festivals, to a meeting to discuss the use of Placer.ai at our events. The meeting will be held at the office of a non-profit that promotes tourism in my city, and I view it as an arm of the government because they are the primary and officially-sanctioned source of visitor information for our area, and they work closely with county and city government.
My director and most of our board is comprised of immigrants who either have limited English skills, low tech proficiency, or both. I'm being sent to this meeting because I'm a Gen Z native English speaker, but my knowledge of data collection, AI, and privacy in the digital age is not the best. We have a lawyer who specializes in this sort of thing coming with us, as well, to further back us up.
Some concerns my director has expressed:

• Placer is an Israeli company. (Regardless of feelings about the Israeli government and the ongoing conflict, we aren't comfortable with a semi-governmental body having a contract with a foreign-based company collecting location and demographic data.)
• How this data is being collected and used, especially by a semi-governmental office. (Big one for us as an organization primarily comprised of immigrants. We live in a very Republican state.)

I have some notes and did some research, but I'd like to hear from you all who might be better versed in this. A lot of the people in our organization hear "AI" and get real scared, and I want to be able to reassure, or at least, better educate them. Meeting is later today (1PM EST), and I can share my notes afterwards if you all are interested.

This has been discussed a few times over on the general Pittsburgh subreddit (and I'm sure some of you have commented on those threads), but just wondering if there is a consensus from the "bike-specific" community on this issue?
Some general points:

1. I assume there is a fair degree of overlap between folks who are interested in biking/bike infrastructure and folks who support further development of public transit options.
2. For its part, it appears that the firm that is proposing this use, Railroad Development Corp., has been advocating for this potential use for, at least, 6 years (and the County and/or associated redevelopment entities, have, apparently, repeatedly rejected the dual use proposals).
3. PRT has included the potential to develop this route in long-term plans, although it does not appear that any substantial steps were ever taken toward developing this route, and certainly no funding was available to do so.
4. Trail advocates worked diligently for several years to secure an agreement with the owners of the Brilliant Branch, and after securing such agreement, and seeking approval from a government entity known as the "Surface Transportation Board," Railroad Development Corp., is attempting to insert itself into the process, in order to promote its desired use.
5. Railroad Development Corp. claims that there is community support for its proposal, and it did file five (5) letters of support with the Surface Transportation Board, including letters from two rails with trails advocates, a CMU professor and two reps from transit organizations ("Pittsburghers for Public Transit" and "Mobilify Southwestern Pennsylvania").
6. In their filing with the Surface Transportation Board, Railroad Development Corp. and its affiliate, Pop-Up Metro, claim that the trail only usage represents, "the parochial policies advocated by the former Allegheny County Executive" and that such proposal is "short-sighted and is merely reflective of local politics".
7. Pop-Up Metro claims that it will invest, at a minimum, $3.5 million in the project, although it is not necessarily clear what percentage of these monies would go toward the trail development vs. the proposed transit use.

I dunno, what do yinz think?

News Link: https://www.globenewswire.com/news-release/2024/05/14/2881828/0/en/Dyadic-Announces-First-Quarter-2024-Financial-Results-and-Highlights-Recent-Company-Progress.html
Human Health Sector

• Final Clinical Study Report has been issued for the First-In-Human Phase 1 clinical trial demonstrating safety and antibody response for DYAI-100, a recombinant protein receptor binding domain booster vaccine candidate for protection against COVID-19 infection
• Entered into several fully funded vaccine and antibody projects covering more than twelve targets, five of which are funded by two of the top ten pharmaceutical companies
• Successfully expressed a H1N1 influenza antigen in our collaboration with the Vaccine and Immunotherapy Center (“VIC”) at Massachusetts General Hospital
• Announced strategic partnership to develop affordable rabies prophylactics and vaccines using C1-cell protein production platform
• Published a manuscript of preclinical studies on C1 produced monoclonal antibody in non-human primates and hamsters in prestigious peer-reviewed journal Nature Communications
• Advanced collaboration with Israel Institute for Biological Research (IIBR) targeting bio-threats and emerging disease solutions
• C1 produced adjuvanted recombinant ferritin nanoparticle H5N1 “Bird Flu” human vaccine candidate demonstrated a strong immune response in animal studies

Animal Health Sector

• C1 produced adjuvanted recombinant ferritin nanoparticle H5N1 “Bird Flu” human vaccine candidate demonstrated a strong immune response in animal studies for potential use in poultry, cattle and other animals
• Expanded collaboration with Phibro/Abic to develop vaccines and treatments for companion and livestock animal diseases

Alternative Proteins Sector

• Executed a term sheet to utilize our microbial protein production platforms to develop production strains for the production of recombinant serum albumin
• Advanced development of 6 product candidates for non-pharmaceutical applications utilizing the Dapibus™ platform technology

Corporate

• Closed a $6.0 million convertible note in a private placement, with a conversion price of $1.79 and no warrants
• Appointed Mr. Patrick Lucy as Board Chairman and Mr. Joe Hazelton as Chief Operating Officer
• Cash and investment grade securities of $12.1 million as of March 31, 2024
• Financial results and business update conference call scheduled for 5:00 p.m. ET today

JUPITER, Fla., May 14, 2024 (GLOBE NEWSWIRE) -- Dyadic International, Inc. (“Dyadic”, “we”, “us”, “our”, or the “Company”) (NASDAQ: DYAI), a biotechnology company focused on the efficient large-scale manufacture of proteins for use in human and animal vaccines and therapeutics, as well as non-pharmaceutical applications including food, nutrition, and wellness, today announced its financial results for the first quarter of 2024 and highlighted recent Company progress.
“We continue to execute our business strategy to focus on near-term pharmaceutical and non-pharmaceutical applications for our proprietary and patented C1 and Dapibus™ protein production platforms and pipeline products,” said Mr. Mark Emalfarb, President and CEO of Dyadic. “One of our key highlights was the successful completion of a Phase 1 clinical trial that met its primary endpoint of safety and reactogenicity affirming the safety of proteins produced by Dyadic's C1 platform in humans. We believe this milestone not only establishes the safety of our platform but also provides a solid foundation for C1 technology’s future applications in human and animal vaccines and therapeutics. With the H5N1 ('Bird Flu') virus outbreaks in poultry and U.S. dairy cows, along with one recent human case, we are seeing an increasing interest in our H5N1 'Bird Flu' ferritin nanoparticle human vaccine candidate, developed with ViroVax. Additional animal studies indicate that the vaccine candidate has the potential to generate high neutralizing antibodies for use in cattle. Our Q1 2024 achievements demonstrate our ongoing commitment to enhancing our microbial platforms for diverse applications, and our dedication to improving health for humans and animals, while tackling the challenges of sustainable food production.”
Mr. Emalfarb continued, “As we progress into the second quarter, our Company continues to focus on enhancing the Dapibus™ platform, designed specifically for non- pharmaceutical uses in industries such as food, nutrition, health, and other bioproducts. To accomplish this goal, we have honed our business development strategy, focusing on key areas where our technologies can deliver the greatest impact with shorter commercialization timelines. Our strategy includes simultaneously targeting multiple offtakes for a single product in several corresponding business segments and seeking out new opportunities that are in line with our strategy.”
Joe Hazelton, Dyadic’s Chief Operating Officer, elaborated, “In addition to operational advancements, we also strengthened our financial position with the issuance of $6.0 million in convertible notes, which will be used to accelerate and exploit our strategic objective of near-term revenue generating products and commercialization opportunities for pharmaceutical and non-pharmaceutical applications. We believe that product opportunities such as recombinant human albumin and alpha-lactalbumin provide Dyadic with multiple monetization opportunities as a licensed product or cell line in pharmaceutical, diagnostic, and food applications. We are confident that our strong position, both financially and scientifically, will enable us to implement our business plans with improved capabilities and resources. We are enthusiastic about our future prospects and remain committed to providing value to our customers and stakeholders.”
Recent Company Progress
Corporate Events:

• On March 8, 2024, the Company issued an aggregate principal amount of $6.0 million of its 8.0% Senior Secured Convertible Promissory Notes due March 8, 2027 (the “Convertible Notes”) in a private placement in reliance on the exemption from registration provided by Section 4(a)(2) of the Securities Act of 1933, as amended. The purchasers of the Convertible Notes include immediate family members and family trusts related to Mark Emalfarb, our President and Chief Executive Officer and a member of our Board of Directors, including The Francisco Trust, an existing holder of more than 5% of the Company’s outstanding common stock.
• On March 28, 2024, the Company announced changes in the leadership roles of the Board and senior management team: the appointment of Mr. Patrick Lucy as Chairman of Board of Directors and promotion of Mr. Joe Hazelton to Chief Operating Officer.

~Human Health Sector~
DYAI-100 Phase 1 Clinical Trial
DYAI-100, a C1-SARS-CoV-2 recombinant protein RBD vaccine candidate, is the first C1-expressed protein tested in humans. The Phase 1 randomized, double-blind, placebo-controlled trial was designed as a first-in-human trial to assess the clinical safety and antibody response of DYAI-100, produced using the C1 platform and administered as a booster vaccine at two single dose levels in healthy volunteers. Following regulatory clearance from the South African Health Products Regulatory Authority (SAHPRA), the trial was initiated in 1Q 2023, with the last patient visit occurring in 3Q 2023. On November 29, 2023, the Company announced the top-line safety results, indicating that the study has met its primary endpoint that both the low and high dose levels of the vaccine are safe and well tolerated among participants. Additionally, the vaccine has been shown to induce immune responses at both dose levels, suggesting its potential efficacy in generating protective immunity against the target virus. The study has been finalized, and the final Clinical Study Report has been issued, demonstrating that the DYAI-100 vaccine met its primary endpoint of safety and reactogenicity.

• In April 2024, Dyadic and its development partner ViroVax reported pre-clinical animal testing on a ferritin nanoparticle H5N1 bird flu recombinant protein human vaccine candidate that demonstrated a strong immune response in rabbits. The potential vaccine combines Dyadic’s C1 single step ferritin nanoparticle H5N1 antigen production with a novel adjuvant from ViroVax. Additional animal studies are being carried out that preliminarily show that this H5N1 bird flu vaccine has the potential to be used in humans.
• Successfully expressed H1N1 influenza antigen in the fully funded research collaboration with the Vaccine and Immunotherapy Center (“VIC”) at Massachusetts General Hospital to express vaccine antigens for influenza A and other infectious diseases, as part of a US $5.88 million award from the Department of Defense (“DoD”).
• On March 25, 2024, the Company entered a funded research collaboration with a top ten pharmaceutical company to develop a vaccine antigen and a monoclonal antibody produced from the C1 technology.
• In March 2024, a manuscript of preclinical studies on C1-produced monoclonal antibody in non-human primates and hamsters was published in the prestigious peer-reviewed journal Nature Communications. A non-human primate challenge study completed dosing of a C1-produced COVID-19 monoclonal antibody (mAb) that had previously demonstrated broad neutralization and protection against Omicron (BA.1 and BA.2) and the other earlier variants of concern in hamsters. Preliminary results obtained from the challenge study with the SARS-CoV-2 Delta virus on non-human primates demonstrated potential high protection. This was the first time a C1-produced monoclonal antibody was used in a non-human primate study validating the safety and efficacy of a C1 produced antibody for infectious diseases.
• On February 28, 2024, the Company’s Dutch subsidiary, Dyadic Nederland BV, entered into a strategic partnership agreement and collaboration with Rabian BV (“Rabian”), a Dutch innovative SME founded by experienced entrepreneurs and vaccine scientists. Awarded by Eurostars for the AVATAR project, a part of the European Partnership on Innovative SMEs (small and medium-sized enterprises), and co-funded by the European Union through Horizon Europe. Rabian will use the total funding of approximately Є1.7 million leveraging its expertise in virology to develop a rabies vaccine using Dyadic’s C1 protein production platform to tackle the challenges posed by rabies, particularly in lower- and middle-income countries. Dyadic is expected to receive an equity stake in Rabian, fully funded research and development costs, and specified product milestones and royalties upon commercialization.
• On February 21, 2024, the Company announced it has advanced its collaboration with the IIBR and its commercial arm Life Science Research Israel (LSRI), to target emerging disease solutions. This partnership aims to leverage Dyadic’s expertise in microbial platforms for flexible scale protein bioproduction and the IIBR’s antibodies and antigens discovery capabilities to develop and manufacture innovative solutions for addressing emerging diseases and potential bio-threats. Through this collaboration, both parties are working towards the development of effective treatments and vaccines to combat global health challenges with the intention of future commercialization (to date, the framework is non-binding and subject to the execution of a binding agreement to be negotiated by the parties) through collaborative out-licensing initiatives.
• On February 13, 2024, the Company announced a strategic partnership with Cygnus Technologies®, part of Maravai LifeSciences®, who have developed the C1 Host Cell Protein ELISA Kit for the quality release of products produced using Dyadic’s protein expression platforms. The C1 Host Cell Protein ELISA Kit is now available for purchase on Cygnus Technologies website under Fungal HCP ELISA kits tab.
• On February 6, 2024, the Company announced it signed a fully funded evaluation agreement including a commercial option with an undisclosed leading global biopharmaceutical company to design and produce recombinant proteins using Dyadic’s C1 microbial protein production platform.

~Animal Health Sector~

• On March 15, 2024, the Company expanded its collaboration with Phibro Animal Health/Abic Biological Laboratories Ltd to develop vaccines and treatments for companion and livestock animal diseases.
• C1 produced adjuvanted recombinant ferritin nanoparticle H5N1 “Bird Flu” human vaccine candidate demonstrated a strong immune response in animal studies for potential use in poultry, cattle and other animals.
  • The H5N1 C1 produced bird flu ferritin nanoparticle vaccine elicits high neutralizing antibodies against all three virus isolates (including Texas) of the H5 virus in livestock.

~Alternative Proteins Sector~
Dyadic is advancing a pipeline of differentiated product candidates that leverage its microbial protein production platforms, including Dapibus™ which have demonstrated the ability and efficiency to enable the rapid development and large-scale manufacture of proteins at low cost in a wide range of non-pharmaceutical applications and commercial use.
Cell Culture Media Products

• In March 2024, the Company executed a term sheet with a large global albumin manufacturer and distributor to develop and license Dyadic’s recombinant serum albumin. The Company’s animal-free recombinant serum albumin projects were initiated in late 2022 using Dyadic pharmaceutical cell lines for use in potential therapeutic, product development, research, and/or diagnostic human and animal pharmaceutical applications. The Company has completed the initial analysis of its recombinant albumin products and has Certificates of Analysis for recombinant human and bovine albumin that demonstrate comparability to reference standards used in the testing.
• In March 2024, the Company entered into a co-promotion agreement with Biftek Co. for the promotion of growth media supplement for cell culture.
• The Company is undergoing a project to produce recombinant transferrin for use in cell culture media for the alternative protein industry.
• The Company is currently sampling recombinant bovine albumin for application testing as growth media for the cultured meat industry.

Non-animal Dairy Products

• As previously announced, in September 2023, the Company entered into a development and exclusive license agreement to commercialize certain non-animal dairy enzymes used in the production of food products using Dapibus™ and received an upfront payment of $0.6 million in October 2023. The Company believes it has achieved the specified target yield level required for a milestone payment upon verification by its partner, and the development of a second enzyme is progressing as planned.
• The Company has developed a highly productive strain and is actively sampling recombinant alpha-lactalbumin, a whey protein, and is currently negotiating several development and commercialization agreements.
• The Company is undergoing a beta-lactoglobulin animal-free recombinant whey protein project, expected to begin sampling in the late third quarter.
• The Company is undergoing a recombinant lactoferrin project, expected to begin sampling the product in the late second or early third quarter.

Bio Industrial Products

• The Company has developed three enzymes, with plans for two additional enzymes, that have the potential for use in multiple industries, such as dairy, nutrition, biogas, biofuels and biorefining. Several initial targets are under evaluation with interested parties.

Financial Highlights
Cash Position: As of March 31, 2024, cash, cash equivalents, and the carrying value of investment-grade securities, including accrued interest, were approximately $12.1 million compared to $7.3 million as of December 31, 2023.
Revenue: Research and development revenue and license revenue for the three months ended March 31, 2024, decreased to approximately $335,000 compared to $934,000 for the same period a year ago. The decrease in research and development revenue was due to the winding down of several large research collaborations conducted in 2023. For the three months ended March 31, 2024, the Company’s revenue was generated from ten collaborations compared to seven collaborations in the same period a year ago.
Cost of Revenue: Cost of research and development revenue for the three months ended March 31, 2024, decreased to approximately $144,000 compared to $727,000 for the same period a year ago. The decrease in cost of research and development revenue was due to the same reasons as for revenue described above.
R&D Expenses: Research and development expenses for the three months ended March 31, 2024, decreased by 35.5% to approximately $523,000 compared to $811,000 for the same period a year ago. The decrease reflected the winding down of activities related to the Company’s Phase 1 clinical trial of DYAI-100 COVID-19 vaccine candidate and a decrease in the amount of ongoing internal research projects.
G&A Expenses: General and administrative expenses for the three months ended March 31, 2024, increased by 20.9% to approximately $1,789,000 compared to $1,480,000 for the same period a year ago. The increase reflected increases in business development and investor relations expenses of approximately $138,000, audit fees of $99,000, management incentives of $59,000, and other increases of $59,000, offset by decreases in insurance expenses of $29,000 and legal expenses of $17,000.
Loss from Operations: Loss from operations for the three months ended March 31, 2024, slightly increased to $2,126,000, compared to $2,050,000 for the same period a year ago.
Net Loss: Net loss for the three months ended March 31, 2024, was $2,010,000 or $(0.07) per share compared to $956,000 or $(0.03) per share for the same period a year ago. The increase in net loss was derived from the sale of the Company’s equity interest in Alphazyme LLC for $989,000 in 2023.
Conference Call Information: Date: Tuesday, May 14, 2024 Time: 5:00 p.m. Eastern Time Dial-in numbers: Toll Free 877-407-0784 International +1-201-689-8560 Conference ID: 13743568 Webcast link: https://viavid.webcasts.com/starthere.jsp?ei=1650831&tp_key=0f89478e24
An archive of the webcast will be available within 24 hours after completion of the live event and will be accessible on the Investor Relations section of the Company’s website at www.dyadic.com. To access the replay of the webcast, please follow the webcast link above.

Simple as title. I've read some comments even from flaired people of 1400 rating (top 5% in Chess.com) that moving all your pawns and promoting them in a won end game is "taunting" the losing opponent. With the context obviously referring to online chess. It is not. In over-the-board games it might be considered rude to resign "early" if your opponent truly wants a learning experience from the game, but opting not to resign when your opponent has enough time (say, 15s or more) to get a mate with material on the board might be considered rude as well.
Online this does not matter. I'm all for learning ticks and trips to get a dirty stalemate on the board. But if you honestly think that your opponent with over a minute on the clock, who has two or more queens on the board against your lone king is taunting YOU, you're mistaken. Most humans want to see the number go up. GothamChess wants to see the letters go up from IM to GM. I want to see my number go up, so as soon as I have a winning endgame, I simplify and make as many premoves as I can. I'm already thinking about the next game, what mistakes I clearly did in this game and why I still won. I'm not spending any more brain power than necessary in KQP v K endgame. IF the endgame needs finesse, then it's good to play it to the end to see if you can quickly come up with faster mates.
If you do not respect your own time enough or think that you need to play the game to the end to avoid a tilt, go for it. But if you want to see your number go up, take the L, resign in a lost position and move on to the next game or go through the game to see where your mistake was.

Currently employed ako, sbrang toxic punyeta. Recently, nagkaroon ako ng eligibility para ma promote ako. Yung salary ko, kung maging okay, tataas. Ito na ang problema ko.
A: • May job offer ako na sobrang near sa akin, 10 mins walk, kaso lower than 10-11k yung sahod. • Nakapasok ako on my own talaga, nag exam ako, nilakad ko etc. • Di ko alam if toxic and wala akong kakilala talaga at all sa loob PERO lima lang kami sa position. Sa buong unit, nasa 7-8 people lang kami kasama na boss. 4 kami na same position, 1 boss, 2 admin tas may isa pa ata. • Kaso, pag nag leave ako for boards, idk if may mababalikan ako.
B: • Level 3 lang ako ngayon sa current job kasi wala pa akong eligibility pero pang Level 22 yung work binibigay kasi dun din daw papunta pag may eligibility na. • Mas may security yung pag leave pag mag boards na, may babalikan ako after boards. May mga kilala rin ako sa loob na higher up. Kaso, yung position na aangatan, "iveverify" pa pero okay na sa ibang bossing kung ma verify na meron pa nga, baka daw kasi abolished na kasi matagal atang nabakante sabi ng mga chaka sa office. • Also, talamak ang bullying. Ngayon ngayon lang, nasimulan na akong mabully. • Nakakainis lang din na na-timbrehan yung isang superior na madami daw nakatenggang work sa akin. Ang akin naman kasi, ako nang ako yung tinatambakan ng trabaho eh yung mga nasa Level 22 na talaga hayahay buhay, mga basic shit lang binibigay. Ako, isang bungkos ng papel isahang lapag. Napaka inconsiderate nung mga level 35.
Idk ano pipiliin. Antayin ko ba if meron talaga or opened pa yung position or kagatin ko na current job offer?

This is what I posted on the board game community in Korea, and I'm also translating and posting it on Reddit!
The translation and text inspection took a long time, but I'm posting it because I think croquinol gamers from other countries will enjoy reading it.
(I don't know how to put pictures in between when writing on Reddit. If you're curious about pictures while reading, please visit the link below. You may not understand Korean, but pictures are visual information so they can be understood universally)
https://boardlife.co.kbbs_detail.php?tb=community_post&bbs_num=26766
Not long ago in early May, I ran a croquinol booth for students and parents at a Children's Day event (it was held on the grounds of the University of Education)
The head of the school affairs department suggested, "I heard you like board games, do you want to run a booth?" so I thought very hard. Actually, it was bothersome.
In the end, I accepted because I wanted to make good memories with children as well as selling croquinol. At first, I thought it was easy to take a few croquinols and play a few rounds.
It wasn't long before I realized that the idea was very wrong. This is because there were so many things to consider operating the booth. The program should be organized in consideration of the number of users and the number of people visiting.
The arrangement of objects and the movement of people should also be considered. I shouldn't think, 'I'm done explaining the game to the students in moderation and watching them play.'
I have to think about the details. I thought about it until the day of operation and right before it started. Now that it's been decided so far, I'll have to recruit staff to run it together (this was the most difficult problem)
Finally, find out the products to give to the visiting children and purchase them, purchase notices to be installed in the booth, and other things necessary to proceed or make them
For two weeks, I spent a lot of time and energy thinking about and preparing for how to operate the booth. I thought a lot about what to give as the prize, but it was finally decided to go down
(1) Pokémon Key Chain Pokémon is definitely a successful IP!!
I decided it right away because it looked so pretty and the quality looked good. There were some that were really cheap, but the quality was really... It was a pity, so I put in more budget
(2) ritter sport chocolate It's economical because there are 200 in a pack I tried one to see if it's poisonous What????? This chocolate tastes pretty good...
(3) Crockinol Pencil (Steadler + Engrave) Originally, I didn't want to give pencils, but if I imprint them and give them to students, I thought they could remember croquinol for quite some time, so I made it meaningful.
If you look closely at the pencil, you can see the image of a disc bouncing with a finger. (○ ● ☜) I made it using the basic characters on the keyboard. Haha.)
It took a long time to think of the word 'dream tree' in the engraved phrase. (Offered words: rookie, genius, child, master, king, god, etc.) Since there are no other people to help me, I planned and produced a lot of things by myself.... lol
I recruited the operating personnel as follows
Head of the school affairs department -> Recruit me (one-person planner and business manager): Let's compare and analyze croquinol sales and rest at home and then experience it. Decided
Me-> First cast (S teacher): A versatile teacher who has been in the next class since we met in the 6th grade this year He became interested after being introduced to Crockinol by me. Enjoying Crockinol at home with his wife. Canadian style. (He said he was doing it without giving it away.) After receiving a proposal from me, "I'll do all the preparations, so please come and let the children know the games without any burden," he decided to participate after much consideration. I'm playing with my kids in the classroom, and my croquinol skills are increasing rapidly. I'm planning to promote the entire 6th grade croquinol competition later.
Second cast (Teacher C): My younger brother who met as a manager and a staff member at my last school and became very close. The same person who said in an old article that he helped move the classroom!
Together, we played about 400 rounds of croquinol 1:1 match. He made a lot of mistakes in his early days, but after hundreds of editions, he became enlightened at some point. He has become quite a master.
His powerful shots made a lot of crazy scenes. Among them, he sent five discs of his opponent to a ditch at the same time. When he was asked by me to help him, he accepted without hesitation. (He is expected to participate in the next event.)
Third cast (Teacher K): I am a teacher from another region, and I am close to him because I got to know him in a club. She was the last to be recruited, and she suggested liter port chocolate and keychain among the product ideas. Pencils were also highly recommended when I was thinking about it.
Lastly, he volunteered after seeing me thinking about recruiting one more person.
She's the only teacher who doesn't have a croquinol, and she doesn't usually have a chance to train, so she's still a beginner's skill.
Rather, a person who is expected to revitalize the booth operation because of that. (If teachers do too well, all students lose.) For the record, she has a board gamer gene that can also play Arcnova board games.
※ In addition, there is a sad history of rejection and subtly falling over during the recruitment process.
And I started setting it up on the day!! Visit early with teacher C and install one croquinol on three tables in the tent
At first, I was worried because the table was in the shape of a rectangle, but I could put things here and there. If you put the croquinol at an angle on the table, it was possible to conduct a 2:2 team, so there was no problem.
After I finished setting up, I sat down for a bit and tried a croquinol test. Played without any problems. The shot was even better because I told them to cut their nails, including myself.
However, there was a lot of dust on the tables and chairs provided by the company, so I hurriedly cleaned them. The remaining two operators also narrowly joined, and a total of four people were matched.
After that, I had time to start operating the booth as a whole They're here...!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!! The name of the booth was 'Gather up here if you're confident in flicking', but I think I drew some aggro. Other places looked healthy like making animal bracelets, but our booth was like, "You! Come if you're confident!"
The booth was originally planned like this Planning the rules of the game: - If you feel uncomfortable, you can stand and shoot freely - In the case of 1:1, the original use of the 1/4 shooting line based on North America and Canada, rather than the use of the 1/2 shooting line that changed the rules in Korean company Korea Board Games. - A student who is too young is forced to shoot with a line forward. Two places are experience seats and listen to and experience the rules 1:1 or 2:2 (Parents and friends can participate together) - The experience gift is one litre pot chocolate - Rule Description -> Shot Practice -> consists of a two-game friendly
If you have learned the rules through the experience, go to the challenge seat of one place and challenge 1:1 or 2:2 (you can also participate together) - If you win, you'll get a Pokémon keychain, even if you lose, you'll get a 1/3 chance of a keychain and a 2/3 chance of a pencil through a lottery - Using one chance card, we will proceed with two sets, and if the student draws or wins even one set, it will be considered a victory. - Re-challenge possible when you line up again The booth gradually gathered and filled the corner, and the line got longer
I repeated the explanation and game so wildly!
The first episode : Even though it was in the shade of the tent, the temperature was high, so the chocolate melted. The student said it melted, so I touched it and it was liquid! Unfortunately, we can't give these defective products to students, so we decided to go to the challenge seat without giving them away in the experience seat.
The second episode : Our classmates are here! I heard a voice saying, "Teacher!" and I can see the 6th grade girls in my class
Of course, we played the game. I tried to lose, but I thought that if I lost too much, the student would notice, so I made mistakes from time to time, but these guys made more mistakes!
It ended with me winning or drawing (I should have made it more clear and lost... lol) I said, "This is just an experience seat, so it doesn't matter, show your real skills in the challenge seat," and sent the girl to another corner
The third episode : People were buzzing that a very famous politician visited the booth next door. (He was Korea's presidential candidate.) I looked up and saw the face that I saw on screen Although I was curious, I had my day job as a board gamer, so I welcomed students and focused on explaining the rules. Later, I found out that he talked to a student who experienced our booth and passed by
The 4th episode : The booth operators were not given a separate lunch break! It was announced that they would take turns eating lunch boxes. There were quite a few people... and I barely had time to eat. One person will be in charge of one booth, and one person will take turns eating I'm the type to eat slowly while tasting the taste, but I didn't have much time to relax on this day, so I sat on the stand and came back in a hurry that I couldn't even feel the taste
The fifth episode : There are so many people, and especially in the case of the challenge seat, the waiting line is longer, so to solve the bottleneck, we decided to take both the place and challenge as an experience seat It was the same with the booth I was in. I don't know what this day is... I made more mistakes than usual and often missed shots because I was nervous dealing with children. Hahaha
The 6th episode : The operations staff at the next table said, "A kid came up with a challenge and beat me." He got the prize, of course But after that, the student was still in the viewing room and gave advice to other participating children, saying, "I win all of them," showing a lot of confidence Then the child triumphantly challenged the management staff again! He must have wanted to win again. What was the result? According to him, he showed the dignity of an adult with his skills to children Of course, he gave away a croquinol pencil this time!!
The 7th episode : I explained the rules so much that the script was automatically made "This game is a 150-year-old game of Canada known to have started in 1876.... "In Canada, it's a daily sport that many families have and play throughout their lives, from childhood to grandmothers and grandparents. The rules are simple: if you put it in here, it's 20 points, this is 15 points....." I can't remember how many times I repeated the script above! The eighth episode : There are people who waited for an hour to listen to it while organizing it I've already experienced it and moved to the challenge seat, but the challenge seat lines are too long... Did they feel like they were waiting for a long line in the amusement park... ㅠㅠ Parents were tired of waiting, so they asked to go to another booth, but the child said, "Since I've experienced it, I really want to try it. I want to take a Pokémon keychain!" and waited a lot. It must have been very boring for parents, but there was no other way. I thought the quality of the operation would be very low to just experience/challenge one game at a time 2 play experience + 2 play challenge was the minimum number of plays to feel a little croquinol
The ninth episode : After eating, I heard parents and children talking "This is where we play Alkagi(flicking). Shall we play Alkagi?" "Let's do it!"
If you had written the booth title, "Who wants to play croquinol?" no one would know croquinol, so accessibility would have been low But when the title said "Alkkagi", I was proud of him coming in without any pressure
The 10th episode : The official closing time of the booth was 4 p.m At around 3:50 p.m., I took a breath and looked at other places, and some places had already withdrawn, and I was usually cleaning up, so the atmosphere was clear But our booth is still full It lasted beyond hours Is this the power of crocinol?
The 11th episode : Time has been deleted I was worried about what if time went by during that long time of operating the booth, but it was a mistake. We were so busy explaining and playing that we didn't have time to look at the clock, and when we came to our senses, it was a time when the end was imminent. I couldn't even go to the bathroom for five hours. Because it was hectic, the operation ended without a comparative analysis of 'Are many people visiting other booths? How popular is our booth?' (When I saw the photos and videos later, I could see that our booth was more crowded than other booths.)
The 12th episode : I tried a lot to react to it in my own way. I really complimented the kid every time he hit the disc. I exaggerated a little bit like I became a YouTuber and shouted a compliment chant out loud A young girl who looked like elementary 1 or 2 sat down (around 7-8 years old) I finished explaining the rules, and asked her to practice shooting a few times. After that, we started playing the game. The girl said she would do it first, and she took the first shot of her life's first game. It went straight into the center hole. There was applause from all around. I said, "Even I couldn't put it in at first. It's amazing." Congratulations on your best experience." She's made a lot of mistakes in play since then, but it doesn't matter at all! There's nothing more touching than the first shot of 20 The parents who were nearby filmed this scene and will cherish this meaningful moment for a long time
The 13th episode : There seemed to be something interesting to see other crocinol tables also clapping, wow, oh, oh From the perspective of planning, all these reactions are a gift
The 14th episode : There were a lot of spectators while explaining/playing There were a lot of comments about the rules of the game "You have to hit the disc when it's on the surface" "Oh!" A male parent was glad to hear that he knew croquinol "I knew this game since it came out last year. It was about 110 dollars, but I didn't buy it because it was expensive." (It's more expensive now. It's about $140)
The 15th episode : We allowed a re-challenge in the 'Beat the Teacher' section, caressing the hearts of children thirsty for crocinol Some students tried again 3 times (The challenge itself takes about 1 minute and 30 seconds for the first round, 3 minutes in total, so it doesn't take much.)
The 16th episode : After 4 p.m., I looked at the other booth thinking about when to organize it, and a boy who looked like a fourth grade in the challenge seat was doing very well Her parents were also amazed by it The accuracy of each step wasn't unusual He said he came back to try it out and do it again Looking at the game, he unfortunately lost to Teacher S by 5 points when he made a mistake of 2 turns in the second half Teacher S told the student. " Try it with that teacher. He's the best While sitting down, I asked, "Do you want me to do it with all my strength or not?" I laughed and asked At first, the student said, "Please be generous!" but later changed his words to "With full strength." "Haha, okay. I'll go with all my strength!" The student said he would attack first and tried an open shot and went straight into the center hole "Wow... does this make sense?" I also chased along the disc in the center hole. That's how I tried to hit my opponent's disc in Hogan's alley and accidentally wasted three turns. The result is that the student who leads by 15 points wins... The child liked it very much and came home with a light step with his parents "Thank you for your hard work. Bye!" When I looked at the playground with the back of my family leaving after saying hello, the sun was slowly heading down, scattering light everywhere and giving the lawn a cozy view What could be a more peaceful landscape. He must have felt really good on his way home. I thought he lost well
Finish writing : When I was in college, I ran a different kind of booth when I was the president of a club, but it was the first time I ran it this way in relation to board games.
At that time, there were a lot of club members and the space was very spacious, so the event was held comfortably, but the croquinol booth was operated in a very minimal condition: 1 tent, 3 tables, 3 croquinols, and 4 people in operation
Still, it ended successfully as it exceeded the time without an accident, so considering that it is the first operation under this condition, it should be considered a great success.
The operation of this croquinol booth was planned by myself and prepared for the program, so I have a lot of attachment.
I'm grateful to the three people who ran it together (they were dispatched from each elementary school publicly and privately). As expected, people are the most important.
I'm willing to do it again if I have to participate in the booth event another month this year or if I have to run it again next year. I think we can do it in a better way than now
For example, I dream of running a mini-contest by installing more tables. There's a mini trophy, and I think the kid who got it will really like it. (Of course we need a lot more people than we do now...!)

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The CBSE curriculum has been designed keeping in mind the overall development of children. It involves not only memorizing books but also understanding the things learned, thinking about them, and applying them in life.It includes many subjects like language, mathematics, science, social science and arts. These subjects give children complete information about the world.

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Doon Public School, located in the heart of Paschim Vihar, is known for innovative methods of teaching, providing excellent education and focusing on the overall development of children. This CBSE affiliated school is known for nurturing young minds and providing a good environment for studies and has become one of the best schools in the region.

Facilities and Infrastructure:

1. Library and Digital Library : Doon School has a big library, where children get various types of books, magazines and things on the internet to read.
2. Playground: The school also has modern playgrounds to promote the physical development and sportsmanship of children.
3. Care for every child: Every child is taken care of in Doon School. If a child has any problem in studies, then a special teacher and support is given to help him.
4. Special for small children: The school has a pre-primary wing for small children. There are play and learning materials so that children can learn easily.
5. New Age Method: New methods of teaching are adopted in Doon School and modern technology is used. Due to this, children enjoy studies and they are able to learn easily.
6. Security and monitoring: Full care is taken of the safety of children in the school. Cameras are installed throughout the school and ID cards are used.
7. Doctor's facility: Doctors and medicines are available in the school so that if the children have any health concerns, they can be taken care of.
8. Tasty and nutritious food: Tasty and healthy food is prepared for the children in school so that they can remain energetic throughout the day.
9. Science Lab: The school has a modern science lab where children can learn by doing experiments.Art Room: Doon School has an art studio so that children can showcase their artistic talent.

Conclusion

In short, Doon Public School is an example of excellent education. This school provides a good environment for the all-round development of children and success in their studies. There are many facilities here, the teachers are hardworking and full attention is paid to enhancing the talent of every child. That is why Doon School is considered to be the best education school in Paschim Vihar.

First time reader of Wolfe and I'm having an amazing time working my way through shadow and claw. I had to read this chapter a couple times to try and grasp it; it's extremely dense. I'm still finishing Claw of the Concilliator so my thoughts may change. I'd love to hear your thoughts.
The Tale of the Student and His Son Analysis
“Once, upon the margin of the unpastured sea, there stood a city of pale towers.”

• The unpastured sea evokes Hamlet “the undiscovered country” death and the unconscious. Pale refers obviously to a light color but also feebleness. However, a tower symbolizes wisdom and stability and the balance of forces (light and dark, fire and water, order and chaos). Wolfe is already painting this city in contradiction.

“In it dwelt the wise. Now that city had both law and curse.”

• Another symbol of duality: loss and gain. The wise give the law but simultaneously curse the city.

“The law was this: That for all who dwelt there, life held but two paths: they might rise among the wise and walk clad with hoods of myriad colors, or they must leave the city and go into the friendless world.”

• Here’s another contradiction: the wise wear myriad colors symbolizing their acceptance of all, but their law is built on exclusion, a brotherhood without.

“Now one there was who had studied long all the magic known in the city, which was most of the magic known in the world”

• The magicians study pan (all). They are comparative mythologists, occultists, Jungians, etc. (This, ironically, is Wolfe). Pan in Greek mythology is a cloven foot and horned god that plays the “pan flute”, and is associated with nature and sex. He is often accompanied by nymphs.

“And he grew near the time at which he must choose a path. In high summer, when flowers with yellow and careless heads thrust even from the dark walls overlooking the sea.”

• High summer is a reference to the “dog days” of summer. In ancient Greece, this was the hottest and most uncomfortable part of summer. It’s called the “dog days” because it coincides with the heliacal rising of Sirius in the constellation Canis Major. Furthermore, the Greeks believed the luminous Sirius (from seiros: scorching) caused the extra hot days. I mention this because it relates to the alzabo which in the Lexicon Urthus is from the archaic Arabic “al-dhi’b” which refers to a wolf, a jackal, or a star in Canis Major.

“How may I - even I who know nothing - have a place among the wise of the city? For I wish to study spells that are not sacred all my days, and not go into the friendless world to dig and carry for bread”

• Another paradoxical and ironic statement: he’s been studying all his life, but knows nothing. A Socratic kind of wisdom but also represents spiraling madness. Critically, he wants to study non-sacred spells; he turns away from the divine.

“ Do you recall how, when you were hardly more than a boy, I taught you the art by which we flesh sons from dream stuff? How skillful you were in these days, surpassing all the others! Go now, and flesh such a son, and I will show it to the hooded ones, and you will be as we.”

• Groomer! And if Wolfe is trying to evoke ancient Greece with this story, it’s well-founded that older Athenian men would often indulge their passion for youth. This would explain the use of the carnal word “flesh” to describe the creative process. Sex magic is a common occult practice and is certainly non-sacred. The passing of seasons represents the cyclical nature of trauma and abuse.
• Wolfe uses very unsettling language: “And the old man who had taught him thought of the beauty of the trees that had for so many years delighted his eyes like the white limbs of women.”

“Winter came stalking into the land from his frozen capital, where the sun rolls along the edge of the world like a trumpery gilded ball and the fires that flow between the stars and Urth kindle the sky. His touch turned the waves to steel, and the city of the magicians welcomed him, hanging banners of ice from its balconies and heaping its roofs with glaces of snow.”

• Perhaps a reference to Saturnalia but does not follow the ancient Greece theme. Saturnalia occurred near the winter solstice because the sun enters Capricorn, the astrological house of Saturn, at that time. Capricorn fits in with the Pan imagery as it too is a goat-like being.
• Saturn represents the cyclical course of time and season (Greek equivalent Chronos). Saturn would regularly devour his own children; this fits into the aforementioned cycle of trauma.
• Saturn is often represented with a sickle: a symbol of mankind’s partial control over the natural world.

“In spring, the most beautiful maidens of the city, the daughters of the magicians, were clothed in green; and while the soft winds of spring teased their golden hair, they walked unshod through the portal of the city, and down the narrow path that led to the quay, and boarded the black-sailed ship that waited them. And because of their golden hair, and their gowns of green faille, and because it seemed to the magicians that they were reaped like grain, they were called Corn Maidens.”

• Here the sickle imagery is introduced directly. The Corn Maidens are human sacrifices, but are compared to grain and corn; sent into the “unpastured sea.”

“Looking from his window saw the maidens filing by, he set aside all his books and began to draw such figures as no man had ever seen, and to write in many languages, as his master had taught him aforetime.”

• Is this not what Wolfe does in his writing? He constantly appropriates ancient words from forgotten languages to do his “magic.”

“ At first it seemed to him that all the skill his master had taught him of old had deserted him, for from the first light to the moonlight he was alone in his chambers save for the moth that fluttered sometimes to show the insignia of Death at his undaunted candle flame.

• More meta stuff: writer's block
• A moth showing the insignia of death is an interesting comparison. This moth could be interpreted as the final stage of metamorphosis before death. It could also refer to the Bombyx Mori, the silk moth. Mori in this sense means mulberry, but mori can also mean death (as in memento mori). The silkworm has a similar symbology to the scythe in that it represents man’s control of nature. This is the domesticated version of the silkworm that relies completely on humans for its survival and is genetically modified to promote silk production. This reflects the city’s practice of human farming and sacrifice.

“Then there crept into his dreams another; and he, knowing who that other was, welcomed him, though the dreams were fleeting and soon forgotten.”

• The Irony here is that although he works tirelessly practicing his magic, he only summons the being when he is not working, asleep and unconscious. He welcomes this being into his mind. “He heard the step, always in another room” He’s unable to pinpoint this being’s being; he can only pinpoint its secondary effects. As he continues his magic, the aftereffects become increasingly pronounced until finally the illusory becomes real. Milton describes hell as “darkness visible.” I think Wolfe is going for a similar effect here.

“Then the student dared turn himself where he sat, and he saw standing before him a youth haughty of port, wide of shoulder, and mighty of thew. Command was in his firm mouth, knowing wit in his bright eyes, and courage in all his face. Upon his brow sat that crown that is invisible to every eye, but can be seen even by the blind; the crown beyond price that draws brave men to a paladin, and makes weak men brave.

• The student’s creation terrifies him, but he doesn’t want to show his fear.
• “Haughty of port” meaning prideful with an air of superiority. Going back to Milton: “round he (Satan) throws his baleful eyes, that witnessed huge affliction and dismay, mixed with obdurate pride and steadfast hate.” Classic Luciferian pride.
• Contrary to popular depictions of Satan, he is one of God’s highest creations: “Whoever he is, the “Devil” is among the very first and best creatures of God. He is, so to speak, perfect enough, wise enough, powerful enough, one can almost say divine enough, to know God and not to surrender to him - to know him and yet opt against him, to desire freedom from him. But since this freedom is impossible in the love and light which always lead to God and to a free surrender to him, it must of necessity be fulfilled in negation, hatred, and rebellion.” (Alexander Schmemann). Satan is God’s highest creation but he is the most base, he is wise yet chooses irrationality, in Wolfe’s description he wears the invisible crown that all see. Satan is an ironic, paradoxical, and tragic figure.
• Milton also describes Satan as a commander

“Often I have seen, like a green serpent called by the notes of a pipe, a column of green slip down the cliff below our city to the quay.”

• Again Wolfe uses Miltonian imagery: “Thus they Breathing united force with fixed thought moved on in silence to soft pipes that charmed Their painful steps O’er the burnt soil.” Both descriptions suggest a snake charmer playing his pipes.
• This connects Satan and Pan: pan pipes as well as ostensible concern for his nymphs

“At this the young man’s eye flashed, and he demanded: ‘Who is this ogre, and what form has he, and where does he dwell?’”

• The ogre is the beast and the minotaur that lives in the west. The West is another symbol of death and the unconscious.

“His name no man knows, for no man can approach near enough…His harbor is an isle to the west, where a channel with many a twist and bend, dividing and redividing, reaches far inland. It is on the isle, so my lore teaches me, that the Corn Maidens are made to dwell; and there he rides at anchor in the midst of them, turning his eye ever to left and right to watch them in their despair.”

• Does no man know its name because no one has discovered it or because it doesn’t exist? Or are both the same?
• Eye of Sauron reference. Masonic all-seeing eye which masons say represents the omnipresence and omniscience of God, but, in reality, represents an all-powerful control system that constrains mankind. When Severian first goes against his guild he says of his fellow torturers: “ I saw them as powerful, the active principle of an inimical and nearly perfect machine.” Severian first realizes that Nessus is a vast control mechanism; the torturers are a gear in the infernal machine.
  
• The beast lies in the labyrinth. The twisting and bending channels describe a labyrinthine structure without directly calling it a labyrinth. When Domnina first observes Father Inire’s mirrors: “She ran to the curtains hoping to find another door behind them, but as soon as she pulled one aside, one of the eight walls painted with labyrinths opened and Father Inire stepped out. Behind him she saw what she called a bottomless hole filled with light.” Wolfe is trying to show that the beast, the control mechanism, is tied to these mirrors.
  
• The young man fleshed from dreams relates to the fish fleshed from reflected light in Father Inire’s mirrors. They are both paradoxical creations; how can one create reality from the virtual (dream stuff and mere reflections)? The fish is clearly a reference to Christ and the ichthys; Domnina even references Pascha. But this Christ is a virtual Christ, an antichrist. In Revelation, the Antichrist is depicted as the ape of Christ, but ultimately the Antichrist is a mere illusionist: “And for this cause God shall send them strong delusion, that they should believe a lie” (Thessalonians 2:11).
  

“For I am Noctua, the daughter of Night, and the daughter too of him whom you have come to slay…For though he did not know why, being of the stuff of dreams he was drawn to her; and she, who eyes held starlight, to him…At this the princess took pity on him, for all who have the stuff of dreams about them seem fair in some degree at least to the daughters of the night, and he fairest of all.

• Noctua means owl from Latin nox meaning night (and she is quite literally from her mother Nox). Nox is an important aspect of Thelema or the occult practices of Aleister Crowley. Nox is the formula of the night of pan, the “crossing of the abyss” and the union with “our lady of abominations” Babalon (from Revelations the whore of Babylon). In Nox, the adept experiences unification with the All through ecstatic destruction of the ego-self, dissolving duality into one or, in other words, nonsense. Ego death is a core element of mind control (MK Ultra and Project Monarch** remember the silkworm symbol).
• It’s clear from this passage and later passages that many others have been sent on this mission in the past. However, Noctua feels a particular affection for this commander.

“At length Night came, and they saw her striding from islet to islet with her bats about her shoulders and her dire wolves dogging her steps. No more than an easy carronade shot from their anchorage she seemed, yet they all observed that she passed not before Hesperus or even Sirius; but they before her. For a moment only she turned her face toward them, and none could be certain what her look conveyed. But all of them wondered if indeed the ogre had taken her without her will as her daughter had said; and if so, if she had not lost the resentment she might be imagined to have felt.”

• Hesperus represents Venus the morning star in Latin Lucifer or light bringer. As Russell puts it, the evening star is the morning star; it represents the drama of a hero striving for the highest seat of heaven but being cast out of heaven (matches the movement of Venus in the sky). Another connection to Sirius.
• Another suggestion that perhaps this quest is not as it seems.

“In ancient times, so it is said, a tattered child, the daughter of a fisherman, found on the sand a stoppered flask, and by breaking the seal and drawing forth the cork became queen from ice to ice. Just so it seemed, an elemental being, strong with the strength of the forging of creation, debouched from the tall smokestacks of their ship, tumbling over himself in dark joy and growing with a rush, as the wind comes.”

• This could be a Pandora’s box reference, critically Pandora. Another dualistic notion, that what saves the day also causes doom. Or perhaps Odysseus’ bag of winds; the aid turns into the curse. Fits into the overall narrative of the story that Severian is both a torturer and a hero. He is “severed” and “severs” into two. Dorcas: “All of you are torturers, one way or another.”

“Then he strode to the rail and looked down; but with such an expression that no one, not even the most brave, dared to look at him. When he lifted his eyes at last, his face was set and grim and with no word to any man he took himself to his cabin and barred the door.”

• Obviously despondent. Either about the evil he released into the world or that his great battle was with a phantasm or that the whole quest was a lie.

“But on the morning of the third day, the young man fleshed from dreams came out of his cabin and began to walk up and down the deck as he was wont to do”

• Allusion to the resurrection of Jesus on the third day. His cabin serves as his “tomb.”

“At this he looked up into the very vault of the firmament. And some thought he prayed, and some that he sought to restrain the anger he felt against them, and some only that he hoped to gain inspiration there. But so long did he stare that they waxed afraid, even as they had when he had peered into the water, and one or two began to creep away. Then he said to them: “Behold! Do you not see the sea birds? From every corner of the sky they stream. Follow them.”

• He’s come back from the dead but is filled with anger.

“None of them ever forgot that night”

• Nothing like an orgy after a long day of work.

“Certain of the Corn Maidens wed those princes who, having spent years so long enchanted that they are loath to leave that life (and have in that time learned much of gramary), build palaces on lily pads and are seldom seen by men.”

• They go out to become demonic forces in the world. Lily pads are a call back to Chapter 2 of shadow: “When I think of my own death, or of the death of someone who has been kind to me, or even of the death of the sun, the image that comes to my mind is that of the nenuphar, with its glossy, pale leaves and azure flower.” The nenuphar exists above and below the water; they exist in two worlds just as their journey took them from the east to the west.

“And when he beheld their dark sails, smutted by the burning tar that had blinded their enemy, he believed them blackened in mourning for the young man, and he threw himself down, and so perished. For no man lives long when his dreams are dead.”

• Absurd ending to the story. You can't help but laugh at the ending. Jonas even suggests that the end of the story has been edited.
• IMO, he kills himself because the “hero’s” journey was never meant to be a success. The hooded ones need the ogre to have the utopia.