Trans fat smashburger culvers
Jeans clocky or no
2024.05.17 09:16 cowboylizard99 Jeans clocky or no
2024.05.17 08:19 archangelsgabriel you don’t have to like every effect of testosterone
this is something that i and i’m sure plenty of other trans guys have struggled with. there’s been plenty of effects of testosterone that i don’t enjoy which has sent me into a spiral of “oh god, what if i’m not trans and this was all a mistake??” (despite being much much happier and more at peace in my body than i was pre-T)
you don’t have to like everything!! i don’t like all of my body hair because i’ve never been a fan of hairiness. i don’t like it thinning my hair. i don’t like being more sweaty and oily. i like feminine fat distribution more than masculine fat distribution. some other things too. me not liking these things doesn’t mean being on T is a mistake! it’s just a matter of what makes you feel BETTER than before. plus, plenty of these things make cis guys insecure too. i mean have you ever met a cis guy who enjoys male pattern baldness??
anyway, if you’re anxious like me and get all up in your head worried that being or going on T is a mistake because you don’t like everything about it, don’t worry. it’s okay to not like some of it. that’s normal! but if it makes you feel happier and closer to how you want to be perceived, then it’s worth it :)
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2024.05.17 07:59 Bragunetzki Is it normal to feel dysphoria due to my Sigma Grindset?
Hello, so I have a bit of a problem. I am a trans woman married to a cis woman, and I make most of the money in our relationship. I understand that she doesn't have the same opportunities that I do. I don't blame her, and I like being able to provide the extra stability.
My issue is that this makes me the breadwinner in our household. A real hustler of sorts. You could say I am on my grind set, perhaps, maybe even a bit of a grustler hindset. And this is a stereotypically male role, which honestly makes me feel somewhat dysphoric. My wife even does most of the cooking. Just because I come home from work all tired and I suck at cooking doesn't mean I don't want to cook! Last month we had a pipe burst, and I had to be the one to replace it. All of this makes me feel like a man, and I start feeling like I'm faking my way through womanhood again.
It's come to the point that when I go to get my paycheck, I look at that juicy fat stack of cash, and instead of imagining all the stuff I can spend it on, I start feeling severe dysphoria right there. And it's some strange dysphoria, too. Everything moves as if in slow motion, and there's this high-contrast filter on top of everything. And sometimes I get these auditory hallucinations, where I start hearing various motivational speakers echoing their words through my head, with some music overlayed on top. I just get the urge to throw the cash into a ditch and go sleep on the street for a night. Then maybe get home and cook dinner for my wife coming from work. For some reason, something similar happened when my wife couldn't make the time to go vote this year, but it's not like our country has a democracy anyway.
Has anyone experienced something similar? Do you know what can be done about this? It's gotten so bad that I'm considering leaving my sigma grindset work behind.
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2024.05.17 07:29 drambikachestclinic What lifestyle changes can I make to reduce the risk of chest pain?
Reducing
the risk of chest pain, particularly if it is related to heart issues or other serious conditions, often involves making several lifestyle changes. Here are some key changes that can help:
1. Adopt a Heart-Healthy Diet
- Increase fruits and vegetables: Aim for a variety of colors and types.
- Whole grains: Choose whole grains over refined grains.
- Healthy fats: Opt for unsaturated fats found in nuts, seeds, avocados, and oily fish. Limit saturated fats and avoid trans fats.
- Limit salt and sugar: Reducing intake of added sugars and sodium can help manage blood pressure and weight.
- Lean proteins: Include sources like chicken, fish, beans, and legumes while limiting red and processed meats.
2. Maintain a Healthy Weight
- Body weight: Keeping a healthy weight reduces strain on your heart. Use a balanced diet and regular exercise to maintain or achieve a healthy weight.
3. Regular Physical Activity
- Exercise: Aim for at least 150 minutes of moderate aerobic exercise or 75 minutes of vigorous exercise per week, along with muscle-strengthening activities on two or more days a week.
- Stay active: Incorporate physical activity into your daily routine, like taking stairs instead of the elevator, walking or biking for short trips, etc.
4. Quit Smoking
- Tobacco cessation: Smoking is a major risk factor for heart disease. Seek support to quit smoking, such as counseling, medications, or nicotine replacement therapies.
5. Limit Alcohol Intake
- Moderation: If you drink, do so in moderation. This means up to one drink per day for women and up to two drinks per day for men.
6. Manage Stress
- Stress reduction techniques: Practice stress-reducing activities such as mindfulness, meditation, yoga, deep breathing exercises, or hobbies you enjoy.
- Sleep: Ensure you get 7-9 hours of quality sleep each night to help manage stress and overall health.
7. Monitor and Manage Health Conditions
- Regular check-ups: Have regular medical check-ups to monitor blood pressure, cholesterol levels, and other heart disease risk factors.
- Manage chronic conditions: If you have conditions like hypertension, diabetes, or high cholesterol, work with your healthcare provider to manage them effectively.
8. Avoid Illicit Drugs
- Substance use: Avoid using illicit drugs, especially stimulants like cocaine and amphetamines, which can cause serious heart problems.
9. Stay Hydrated
- Adequate hydration: Drink enough water throughout the day to maintain optimal bodily functions.
10. Be Aware of Medications
- Medication management: Ensure any medications you are taking do not have side effects that could contribute to chest pain. Consult your doctor about any concerns.
11. Know the Warning Signs
- Early intervention: Be aware of the signs and symptoms of heart attack and seek immediate medical attention if you experience severe chest pain, especially if it is accompanied by shortness of breath, sweating, nausea, or lightheadedness.
Implementing these lifestyle changes can significantly reduce the risk of chest pain and improve overall cardiovascular health. However, it is essential to consult with a healthcare professional before making significant changes, especially if you have existing health conditions or risk factors.
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2024.05.17 07:08 Due-Exit-8310 Protein in a bottle (32g)
How would you rate the quality of these ingredients?
Any alternatives you’d recommend? Not looking for vegan necessarily.
Looking for a superior powder or premade shake for the busier days
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2024.05.17 06:05 TrissaurusRex To all the fat-phobic transphobes trying to bully me into not sharing my journey. Mommy isn’t going anywhere!
I’ve been getting a ton of fat-phobic comments and messages lately. Their obvious goal is to shame me into not posting my joy. I’ve finally gotten to a point in my life where I completely love who I am, how I look, and the energy I’m putting out into the world. Absolutely nothing is going to change that. I’m here to share more proud fat trans girl representation and nothing is going to stop me. So hold onto your butts because Mommy is only going to be absolutely unapologetically herself! Which means proud, loud, and ofcourse sluty!
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2024.05.17 05:32 Longjumping-Notice76 Is this per bag?
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2024.05.17 04:55 girl_class Girls. Help!
Ladies, this is my first summer as an out trans woman. I’m really trying to make up for lost time!!! The problem is every time I try on things I think are cute I can’t quite pair everything in my wardrobe together. Cute shorts? I only have shirts that make me look like a little boy. Cute top? No idea how to wear pants with it. I’m 24, 6’2 and fairly skinny, but I still carry a lot of fat in my stomach instead of my hips. What should I be looking for in terms of garments or silhouettes to try and counteract my shapelessness?
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2024.05.17 02:53 minimumaxima Flares from CoQ10 demystified [How I hacked my flox — Personal Story]
Hello, everyone! It's been a while since I posted anything or even visited the sub. I do not visit the sub anymore as I collected all the information I needed long ago and staying on the sub only led to more thinking about flox. Focusing on other areas of life has been a great life hack for me! I have done a lot of positive things in the past half a year - I am starting my own business, been meeting new people and making a lot of new friends. Flox has changed me for the better.
I want to preface this by saying that I was probably the only person (or almost only as I've met maybe 1 or 2 other people on Reddit) who claimed flares from CoQ10. It actually flared me quite a lot — sometimes I could handle 100mg and sometimes even 30mg would lead to terrible pain. It was frightening to be one of the rarest cases in a pool of already rare cases, so, naturally, I tracked reactions to supplements extremely attentively (
u/vadroqvertical won’t let me lie about that) and I have tried a lot (my cupboard is full of supplements — I spent around €3,500 on them in the span of 1.5 years). I will list reactions to supplements and the approximate timeline of when it happened:
— First of all, CoQ10/Ubiquinol flared me not so much 1 month out (tried 100mg ubiquinol multiple times) but it got worse as time went on to the point that April 2023 I could not even take 30mg without great pain. I tried it 1, 2, 3, 4, 5, 6, 8, 16 months out all without luck with varying doses flaring me to different extents. I will outline the reasons for it below;
— Vitamin E flared me a lot 2, 4, 6 and 8 months out. Never tried again. Tried 200-400 IU at a time. Due to poor GSH regeneration through Glutathione Reductase dependent upon B2 and NADPH;
— Benfothiamine flared me as well (doses 150mg-300mg/day). This is due to high sulphite and blockage of complex IV of the Electron Transport Chain in the mitochondria the reason for I will explain further. Thiamine is easily broken down by sulphite in the body and it is broken down into sulphite as well, which causes a negative loop reaction in people with high sulphite levels. Benfothiamine also caused me a severe allergic reaction (extreme anxiety and itching) that gladly did not require hospitalisation but was extremely scary and scarred me psychologically (likely high sulfocysteine activated NMDA receptors);
— Vitamin B6 increased my neuropathy when I got it. Likely due to poor B2 functional status. The problem I was also deficient in B6 and its supplementation led to great improvements in sleep quality once I could tolerate it. Note B6 is easily destroyed by sulphite just like B1;
— Riboflavin flared me (tried at 100mg, doses under 10mg never flared me). This is likely due to unmatched NADPH supply due to high sulphite load in the body (speculative);
— Astaxanthin greatly improved my physical health at 5-6 months out (proving that the core of my issues was solely ROS) but it caused reductive stress (NADH accumulation), which also caused pain, albeit the pain was a different kind and asta caused worsening neuropathy and visual snow. It accumulates in fat tissue, so stopping it was nice with ROS coming to a balance at about 10-12 days after discontinuation (after a loading dose of 36mg/daily for 3.5 weeks) but ROS then came back after it went out of the body further. I did not retry astaxanthin as I realised it caused me reductive stress and neurological issues;
— NAC helped me a damn lot. It was the best antioxidant for me. The problem is it depleted my molybdenum and copper and started giving me allergic reactions (low molybdenum + copper as well as blocked complex IV will lead to way higher sulphite generated from NAC);
— Did not feel much from vitamin D. I live in a very sunny country and tested at 51 (ref. Range 30+) without any supplements;
— Magnesium helped me a lot. #1 supplement;
— Calcium did not help me much in the beginning, actually, caused me heart palpitations. Was fine taking it after a few months;
— Potassium was a good supplement. I took 800mg/day for a while and it supported my muscle health;
— Important: vitamin B5 made me feel a lot better. It took my ROS down like crazy — I could feel normal muscles again, it removed my oxalate pain completely, too but for only a short while like 3-4h.
I have tried many more supplements that were phyto-supplements and such and none of them really helped me beside maybe some placebo effects. Some made me feel worse and were not worth it at all. I did not try anything mood-changing as I was not interested in it. To note, GABA supplement made me feel a little euphoric at first.
It is very relevant that I have been oxalate dumping since 27 Dec. 2023. The description of the experience can be found here:
https://www.reddit.com/floxies/comments/1by0uh0/comment/kyma718/ Now, to the real question: why did CoQ10 flare me even at high nutrient status (just after flox). I have to stress that flares from CoQ10 were much less at the beginning of flox likely due to better nutrient status (it went from extremely terrible to slightly more extremely terrible while 6 months out it went from ‘eh’ to terrible).
- First, I have to say that NAC made me worse long-term. How? Over a long period of time I was taking it and was not watching my copper levels (NAC increases metallothionein and causes poor copper absorption) and molybdenum levels (NAC raises generation of sulfite and it needs molybdenum to be detoxified). Some NAC formulations have molybdenum in them but I was not lucky to get one of those and, due to lack of knowledge, did not supplement any molybdenum. The result was high sulphite and from that high ROS (with a combo of benfo which further increased sulphite it caused me peripheral neuropathy at 5 months). Sulphite causes Fenton reactions when complex IV gets blocked up. H2S (a signalling molecule and a vasodilator) also needs to be detoxified by a CoQ-10 dependent enzyme and turned later into sulphite and then sulphate by molybdenum and complex IV (dependent on copper) and if it is not detoxified, it causes a complex IV blockage and starts Fenton reactions as well as electron leakage during production of ATP, causing ROS. This causes a negative feedback loop that was described in the linked article as follows:
«This can be explained as follows:
1) hydrogen sulfide inhibition of complex IV generates superoxide in the respiratory chain, which becomes hydrogen peroxide,
2) hydrogen sulfide reduces ferric iron to ferrous iron, which makes it release from storage in ferritin,
3) this increases Fenton reactions between free iron and hydrogen peroxide, which generate more dangerous reactive oxygen species like the hydroxyl radical,
4) all of this deplete glutathione,
5) since a major purpose of the trans-sulfuration pathway is to provide enough cysteine to make glutathione, glutathione depletion hyperactivates the trans-sulfuration pathway, leading to more cysteine availability, the excess of which is catabolized to sulfite by alternative reactions that do not produce hydrogen sulfide and therefore do not require CoQ10.»
- In the article linked below, you will see that CoQ-10 protects against reactive oxygen species mainly due to improving hydrogen sulphide clearance (H2S). Therefore, CoQ-10 deficiency did not cause much ROS in complexes I and II but mainly produced issues in Complex III (where sulphite detoxification starts) and complex IV (where the last electrons are delivered during the sulphite-sulphate reaction). Excerpt: «In human cells with CoQ10 synthesis defects from the same study, CoQ10 protected against reactive oxygen species, but suppressing the enzyme that uses CoQ10 to clear hydrogen sulfide abolished this effect. This shows that the reactive oxygen species were coming from poor hydrogen sulfide clearance.»
Considering this, and oh my god, finding this article was like god sent it to me: my CoQ10 flares were coming from poor hydrogen sulphide clearance. At that point there were multiple reasons this could be happening:
- Cellular CoQ-10 deficiency;
- Manganese toxicity;
- Copper deficiency;
- Molybdenum deficiency;
- SUOX (enzyme which converts sulphite to sulphate) or another genetic impairment;
- Blockage of complex IV by something else.
I checked my molybdenum and copper transporting genes, SUOX using DBSNP and my AncestryDNA.txt file, and they were all good (Yes, I know Ancestry does not do a full genomic profile but it still had the main SNPs for that.). I also checked my manganese transporter genes and seemed I was homozygous for an important one but fine with others. It is really hard to estimate how that might affect you IRL, perhaps that would require a real genetic counsellor (or lots of hours spent ruminating again). I also did not think I had any genetic issue since I was very very healthy all my life and had 0 pain or health issues before flox occurred (I have extremely healthy young looking parents that drink, smoke and do whatever they want and have 0 consequences to their health as well).
I took some tests, for example: Genova NutrEval at ~6 months out, full nutrient blood test panel at ~11 months out (abstained for 35 days from any supplements at all, even vitamins and tested literally everything, paid around €1,200) and my CoQ10 levels at both of those occurrences were at 1 & 1.07 in absence of supplementation with ref. Range 0.8-1.4, so it was definitely not low. That way I eliminated #1 and #5. While I was not entirely sure whether genetic issues had to do anything with it, I decided to pretend like they didn’t, since I had to try out other solutions before jumping to the most complex one. I took a lot of molybdenum, so molybdenum deficiency was not at the table for me. In this way I was left with #2, #3 and #6. In the full blood panel, my manganese was slightly high (20.1 with ref. Range <~18) and the SNP people were talking about that caused them manganese toxicity was homozygous for me, so I definitely considered it but manganese when supplemented made me a feel a lot better, actually (mentally, not physically), so I was also likely deficient in it. For now, I just avoid it in supplemental doses but I do not avoid foods containing it. Besides, I do not have iron overload genes that could contribute to manganese toxicity.
I could not take copper because it would lead to high ROS immediately (due to complex IV blockage the reasons for which I will outline further). Considering manganese was likely deficient and not superfluous, I discarded reason #2 and reason #3 could not be fixed by copper, so it was definitely not only copper deficiency but either another factor or another factor coupled with copper deficiency. I was stuck for a long time until I found another article from the same author about B12 and B9 helping to detoxify oxalate. As I said before all this explanation, I have been oxalate dumping throughout the whole process (already 4 months). I should note I was oxalate dumping even before I got floxed (I likely had oxalate overload to my appendix surgery — this is proven by inflamed mesenteric lymph nodes confirmed by 3 MRIs — Sally Norton has the same case of over-absorption in her book) and that is how I actually got the E. Coli they gave me Cipro for (oxalate crystals create a good environment for it in the urinary tract lol) and how I got floxed (I went full circle, lmao). When I was floxed, I was not oxalate dumping for at least a year likely because my body was not in the state to handle the dumping process but it was still affecting me as I will outline further. First of all, I want to say that biotin actually promoted dumping for me as said in the article and not relieved it like it is said in Sally Norton’s book (I am not sure if there is a genetic variation to this). The proposed mechanism of oxalate detoxification in the article is as follows:
«Recall my proposed two-step detoxification process:
- Pyruvate carboxylase [biotin-dependent] converts oxalate to formate.
- Formate is joined to tetrahydrofolate to enter the methylation cycle, be used for the synthesis of purines or DNA, or be converted to carbon dioxide and exhaled in the breath.»
This are also very important words: «There may be more regulation layered on top of this to prevent excessive formate accumulation. It would certainly be preferable to have oxalate crystals cause pain or disrupt the skin than to have formate accumulate beyond the capacity to clear it.» This is why I felt best when dumping. Could eat anything, drink beer, even smoked weed once without issue. Another time though I got too brave, smoked a lot of weed and got a very bad ‘relapse’ but recovered quickly from it. The next morning when using a towel after a shower I had the same pain I used to have 2.5 months out from Cipro (which was extremely bad and took me back 14 months in memories) while before I smoked weed that second time I had almost 0 tendon pain in my daily life apart from oxalate [Here I thought maybe I and DrHungry share similar issues then? He also had an extreme (same in intensity relatively to his flox journey) flare from weed and is also using a lot of sulphur-based antioxidants still. Could such weed flares be related to complex IV dysfunction and/or impaired sulphite clearance?]. In either case, I felt best when dumping, probably because my body was able to regulate formate accumulation and ROS production greatly reduced at those times.
I was sitting outside with my parents and their friends, researching my flox issue when I read these lines: «Formate accumulation is the principle mechanism of
methanol toxicity. Part of its toxicity is driven by inhibiting cytochrome oxidase, complex IV of the mitochondrial respiratory chain, which would inhibit the clearance of sulfite and hydrogen sulfide and block the production of ATP.» It finally clicked. It was honestly one of the best moments in my life when I realised. I made the connection between great improvement from B5, formate accumulation, issues with copper supplementation, general ROS improvement and oxalate everything together. Suddenly, my whole flox journey became crystal clear to me.
B5 is mainly used in the body to create Coenzyme A. An intermediate molecule in the production of CoA is called 4’-phosphopantethine and is used in the enzyme 10-methyltetrahydrofolate dehydrogenase (high formate will pair with THF and form 10-MTHF in the attempt of the body to detoxify formate). This enzyme converts 10-MTHF back to THF and creates NADPH in the process which is used by Glutathione Reductase to regenerate Glutathione. Hence, high-dose B5 led to a lot of those reactions occurring and me feeling a big relief from ROS AND OXALATE, so oxalate is indeed detoxified into formate by biotin-dependent pyruvate carboxylase.
Okay, so theory is very interesting but what is theory if it has no proof? When I read it, I realised I finally cracked my flox but I had to get real proof.
Just a few weeks before this, I drank some wine and got nerve damage (likely from high sulphites in it, again, duh — while this was a terrible experience, it played a role in me getting closer to the solution of my issues). Beer caused me no issues, could drink 10 or more bottles in one sitting, eat a lot of rice with no issue. Before, I had only numb hands and top of feet. After the wine, I had burning up to the knee and burning in palms and behind my shoulders. I got fed up with this, I just decided to methylate the fuck out of my nerves and eat copper not in supplements but from calamari (very high in copper but low in vit A, so no toxicity risk like from liver). At that time, I was dumping and my ROS was not too high. I started consuming around 200g protein per day, eating a lot of copper 3-4mg/day and my nerves really healed a lot. To the point they even became normal after 3-4 days. My vision became brighter, it was absolutely crazy. I was also supplementing 150mg molybdenum/day. After a week of that, though, I started getting ROS back and it was very bad ROS, like almost a year ago when I had low molybdenum and copper from a lot of NAC use. That confirmed my suspicion that my issue was indeed sulphite. Eating almost anything caused ROS for me, dumping stopped since the body had no free reducing agents (NADPH) to support sulphate-producing enzymes (oxalate is transported on sulphate transporters, so it literally could not drive out of the cell because it had no car lol). As you understand, high ROS prevents a lot of enzymes from working and here it causes, as you have probably understood, a negative feedback loop.
So, back to the proof. Since I realised that my issue is probably formate, I just decided to take high-dose B5 again (did not add any high dose B2, B1 or other B vitamins, just took my usual B complex with food). It really helped me a lot, again. I felt almost normal. Then, it caused me some pain but I felt how I was getting better and the next day I took it in the day, then in the evening I ate around 80g carbs and took double the dose of B complex (my B complex has low doses: 10mg B1, 10mg B2, 25mg B3, 20mg B5, 5mg B6, 100mcg B7, 100mcg B9, 50mcg B12) instead of adding a lot of B5 and boom, no pain and oxalate dumping restarted quite more strongly than it even used to be before megadosing protein. So I was in pain for at least 2 weeks dying from ROS and then 2 days of B5 and suddenly I was normal again? It felt like paradise. The next day, I went out with my friends. I was a little nervous since we were going to eat out and we ordered 600g of carbonara (the portions here were huge there). I ate it all at once with 2x my light B complex and guess what happened? NO PAIN, just oxalate dumping. I finally realised that I was right and detoxified formate unloaded my complex IV, allowed sulphate transporters to be created, reduced ROS production from food and suddenly I felt like a normal human being (except the dumping part). I recently retried CoQ10 — no flare. Likely before formate got recreated a lot because I was dumping a lot (if you read my comment, you will understand).
I am not megadosing B5 right now but just stuck to 80-100mg B5 per day, so 4x my light B complex as my B6 tolerance improved a lot. Why I am not megadosing B5 is because oxalate likely blocks conversion of vitamin B2 into its active forms as I at ~11 months out when I did full-testing in the absence of supplementation 35 pre-testing had high molybdenum, iodine, (almost above the ref. Range (113 with ref. Range <120) selenium and very high B2 even though I was cellularly deficient according to Genova NutrEval (at 356 with ref. Range <295).
Hence, we can understand what happened to me from the beginning:
- Oxalate overload led to formate overload as oxalate is converted to formate through the action of biotin-dependent pyruvate carboxylase;
- Formate overload led to complex IV blockage, high ROS and high sulphite, which also leads to high ROS and also leads to complex IV blockage (negative feedback loop);
- High sulphite destroys vitamins B1&B6 as said in the beginning, which caused endogenous production of oxalate to skyrocket (you can read about this if you google, this information is very available);
- Hence sulphate transporters also got impaired, oxalate detoxification in the form of physical crystals also halted, which led to even higher overload;
- This led to higher formate, this led to even more ROS.
Mega-dosing B vitamins and especially B5 and B9 led to formate detoxification and the ability of my body to detoxify oxalate. This improved me a lot and it definitely feels like it will inevitably lead to my recovery. I feel good now, I still have some remaining neuropathy but it’s minimal and I know what to avoid to not make it worse and how to improve it quickly if I need to. I have no OS from beer, coffee or food. Also, I am dumping a lot right now. You can ask me all kinds of questions that you want and I will try to answer them to my best ability since I know what it is like to be floxed and I will help anyone who is in the same situation. I am only 22 years old and this experience led to me rethinking my whole life. I plan to become an extremely rich person to be able to fund biochemical research in the future and will focus specifically on floxed individuals and I will help floxed people first. I will try to reach my goals as fast as possible, I promise.
I hope this post does not get removed by moderators. If there is anything to moderate, change, or add, I will be happy to do that. All I say here is very attentively selected and fact-checked either from external sources or personal experience. I do not lie and have no motivation to do so. I am only trying to share my knowledge and to help realise others flox is not unbeatable and can be understood and solved — it all depends on individual factors.
Linked articles:
Manganese Toxicity Is a CoQ10 Deficiency https://chrismasterjohnphd.substack.com/p/manganese-toxicity-is-a-coq10-deficiency CoQ10 Deficiency Is Sulfur Toxicity https://chrismasterjohnphd.substa2ck.com/p/coq10-deficiency-is-sulfur-toxicity?utm_source=profile&utm_medium=reader 10-Formyltetrahydrofolate dehydrogenase https://lpi.oregonstate.edu/mic/vitamins/pantothenic-acid#formyltetrahydrofolate-dehydrogenase Can Biotin Help Detoxify Oxalate? https://chrismasterjohnphd.substack.com/p/can-biotin-help-detoxify-oxalate Can B12 and Folate Help Detoxify Oxalate? https://chrismasterjohnphd.substack.com/p/can-b12-and-folate-help-detoxify submitted by
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2024.05.17 01:51 emilylydian Make it make sense :) Smartpop Popcorn
2024.05.17 01:25 veeross87 Got them!
2024.05.17 00:53 BiscuitPuncher Just a lil feelins post
Hi all, I just wanted to send the stuff I'm currently feeling into the aether
Thought 1: So I've been on hrt for 11 months, and I'm getting impatient. I have EXTREMELY soft skin, but my boobs are only just starting to boob, fat redistribution has just not happened, still have a decent bit of muscle mass, etc. I just want to time skip to like 5 years from now. The thought of the future being one where I'm a girl is comforting at least.
Thought the second: For a while I was doubting myself. I thought I was wrong about being trans for a bit, but after lots of introspection I'm now super excited to be a girl. Thinking about how I've wanted this since I was a kid and I finally get to be a girl is an amazing thought, so I'm firmly in the trans club.
Thought the third: my cat is currently laying on me and he's cute
Thought the fourth: I'm scared to socially come out. My friends know, and they're great, but I'm scared for my coworkers to know. When I came out initially, my girlfriend at the time betrayed me. She was initially supportive and everything but one day just rug pulled me and broke up with me (giving me PTSD and a terrible fear of rejection). When I came out to my parents, my mom asked if I like men now (I don't), and my dad said (in supposed privacy) "How is he gonna get a girlfriend now?" Suffice to say I haven't had the best experience coming out. There's some hope in that there's a trans woman at my work but she's a contractor and I work directly for the company so it's not the same. I live in an at will state so they can fire me for that and disguise it as another reason, but I love my job, I don't think I could handle being fired like that, both mentally and financially (if anyone has advice on this topic I'd love to hear)
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2024.05.16 23:56 FA-__-CE Help Tracking Macros
| These are the macros “as prepared” I want to add the macros without the prepared ingredients that aren’t within the contents of the box. The as prepared ingredients are: 3 tbps Heavy Cream & 2 tbsp of butter. Can anyone do this math out for me to where I can input into the app. I have a half assed try and couldn’t figure it out - thanks! submitted by FA-__-CE to MacroFactor [link] [comments] |
2024.05.16 20:22 gamanatoryt I'm not strong enough for this
I feel like Im just not strong enough to deal with my life anymore, let alone trying to transition. Ive been on estrogen since November 1st 2023, and yet... barely any changes. after 6 months, I finally got the courage to ask for some tests. I was at practically nothing. It crushed me. Not only had they put me on a low dose, but they had prescribed me half the dose they both said they would and wrote down they did. Its par for the course for my experience with doctors. Honestly, I think they just forgot. Maybe thats me being charitable. I got my dose raised and started progesterone. Im now 8 months in and... still, nothings's happened. Im going to get my dose checked again, but I know its going to be fine. it was fine last time I checked. My body is almost certainly stuck like this.
I wouldn't be suprised. I got terrible genetics for being a trans woman with such intense dysphoria. Im 6" 1' from my mother's Polish descent. I'm built like a truck. Wide shoulders, narrow waist, Incredibly hairy, and the hair grows back fast. My face is inarguably square. My dad's side of the family is all high weight with fat piling up on the stomach as beer gut and on the neck, even female family members. It may be too early to tell, but Im 90% sure I inherited my mothers non-existent breasts. I haven't had any real breast development. Im not sure I even qualify as A cup. If I've had any breast development, it manages to perfectly pass as moobs.
The truth is I dont think estrogen will make anything better anymore. I just have to live like this.
I tried to lean more into fashion to help me pass, but I have panic attacks shopping, mostly from childhood trauma. I have panic attacks all the time, actually. When I order clothing online they almost never fit, and I dont have enough money to get anything custom fitted.
Ive spent dozens of hours trying to get makeup to look good but anything past foundation I always mess up. My hands are too shakey, like they've always been for precise hand movements.
Even after everything, I look like an ugly man. I dont even look handsome by any standards. Theres nothing there to be confident or happy about.
Ive spent so much time voice training, but even after years I just end up shifting back into speaking like a man after a minute or two. My fem voice is crackled and gravely. Ive tried to make it as soft and clear as I can but I can only push it so far.
Maybe in a decade everything will work out. Maybe in 5 years. But Ive spent my entire life in pain, being bullied, abused, dysphoric to the bone. I'm too weak to stand up for myself, and at the rate things are going, I dont know if I'll even get to simply feel mediocre about my life. I dont know how much longer I can do this.
Ive talked to therapists before. Some tried to help me and failed. Others simply didn't try. A couple sided with abusive parents. I want therapy, even need it, but the market is so scarce, so expensive, and I don't know if I can survive being burned again. Even then, I dont know how many people are even qualified to help me. I dont even know if I'm stable enough to maintain not ending up in a psych ward.
I dont know what to do and I feel like Im drowning. Everything hurts and if I have to live my life in pain like this Id rather just die. Ive been on a handful of antidepressants and none of them worked.
Everyone in a position to help me just ignored me, my entire life. Now Im too unstable to take care of myself anymore. I dont know what to do.
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2024.05.16 18:18 PsychologicalLet4027 need tips for diet/workout
Im 16 and trans (AFAB), 150lbs and about 5'3. im trying to lose fat in my thighs and hips while gaining muscle in my shoulders and arms. Do I need to focus on cutting or bulking for this goal? Also, will building muscle in my thighs make them appear slimmer? How do I do spot reduction in just my legs while building still building muscle? I've tried to do my research but i just dont understand how or if this is an obtainable goal. Pls help!!
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2024.05.16 16:58 East_Alternative_538 Best Porn Subs 2024
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2024.05.16 16:54 belugabishop Positive Experience with Fertility Clinic
I just wanted to add some positivity here and say I've had a great experience with our fertility clinic so far! We're in a red state so I have lots of medical anxiety surrounding reproductive health, but I've been really happy with how lovely our fertility clinic has been. I am a fat, queer, disabled person and they didn't blink an eye when I told them I wanted to carry. They've been so kind and answered all our questions. Most importantly, we're using a known donor who is a trans woman who banked her sperm prior to transitioning. When submitting her paperwork for the vials to our bank, she redacted her dead name and again they did not care one bit. They even correct their pronouns when referring to her! My wife is also a transwoman and they've treated her with nothing but respect. I'm just delighted with how wonderful they've been.
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2024.05.16 16:35 TerraTechy Quick PSA on lgbt
Seen a couple posts here about lgbt stuff and a couple arguments thrown here and there. Wanted to clarify some points I see brought up often, particularly from those who dislike queerness.
Firstly, "Pride" as a movement is not about shoving queerness in everyone's face. It's about recognizing and supporting queerness in our local communities, and providing reassurance that they are safe to be themselves. For those who aren't out, it's about letting them know they have people who can help them and support time when they're ready.
"They're turning our kids gay." Lemme just say that's a big fat lie. When we educate on queer topics and queerness overall, it's to inform people about queerness so they can recognize if they feel it themselves.If you've grown up with an undiagnosed condition like adhd or autism like me, you know the feeling of wishing you knew what to look for earlier. This is similar. It's not telling people to be gay or trans, it's letting them know those are real things and that there are resources if they start to feel that way.
"I just don't like people who make being gay their entire personality" I'm going to ask that anyone who holds this opinion elaborate in the comments,(be nice to them) because more often than not, I see this used to basically say "I'm okay with gay people as long as I can pretend their not." If someone is making you uncomfortable, tell them or leave, but please do not hate an entire demographic because of it.
Tldr; pride is to provide recognition and reassurance to queer people, including those that aren't safe to be themselves. Education on queerness is to help people recognize it in themselves if it happens. Be good people, don't hate, have a good one.
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2024.05.16 10:27 Balsssuperfan I think y’all would like my OC + rant about my bf
| Her name is Bonnie and she’s straight and GNC cuz I really wanted to have a character like this. Also I’m so happy to find this, literally so much posts that describe my feelings perfectly. Before meeting my bf and figuring things out with him (it took many years for us both to heal our traumas and be free in our identities), I was really pissed off that people only see a girl being a top in a relationship as a dominatrix, but that’s not my case at all! I also love to look feminine sometimes but I’m a total service top! And I remember how I was complaining to a friend that I want to wear my pink skirts and stuff but still be a “man” in a relationship, and they were like “well, I think when you wear female clothes you look more like a top, it’s easy to imagine you holding your bf on a dog leash”. AND I tried so hard to explain that I’m the one on a dog leash and people just can’t understand itttt and I’m so happy to find this subreddit. I remember when I was 12 yo I got my first boyfriend and I liked him because he had a beautiful chubby curvy body, and he wore glasses and had cute bangs and was a nerd so I had a crush, but I was so sad that he was trying to be a gentleman for me, I remember how I was begging him to let me walk him home and open doors for him and shit, and he was like well that’s not right. And my mom was saying that I don’t let him bloom his masculinity. Oh god. I turned out to consider myself a trans guy for many years because it was easier for me like that but I kept returning to be a girl every once in a while because I’m not actually trans, I just couldn’t fit my identity into being a girl because society taught me that it’s not normal. To others when a girl is somehow gnc it implies that she’s either a power bottom, a dominatrix or a lesbian. But I’m neither!!!!! And I’m so glad to have my bf we will marry soon and I love him so much he sits on my lap and slaps my face like a lady when he’s angry at me and oh my god I love him. We had so many discussions about him always having crushes on lesbians and failing to date classic women and me dreaming about a boy like him. I have short hair and I’m a fan of 2000s fashion so I enjoy both female and male clothes, my bf usually just dresses in regular clothes because he doesn’t really care about fashion, but his attitude is so… wow… he can be a silly nerd sometimes and then all of a sudden he’s a “dark fem” seductive hottie and I want him both ways. I’m just so happy. Also I always was into fat/chubby guys because they are the curviest. Even on pictures where my bf was skinny he still has that sexy waist and broad hips and shoulders like hourglass figure but male. Damnnnn. submitted by Balsssuperfan to GNCStraight [link] [comments] |
2024.05.16 08:26 c3ber6ng7l why are trans women so obsessed with lying about their transition
*ONLINE
why is it that whenever I talk with a trans person irl they never mention something like:
yea I got multiple orgasms from hrt when I take estrogen I can feel that its the hormone that I was missing all the time, I finally do not feel miserable anymore! 2 Months on HRT and I got C Cups! I got a period from hrt I grew a uterus from hrt 2 years hrt my face changed so much!! my hair thinned out from hrt, lost most of it, dw you don't need laser hrt made me lose so much fat! and I have way less appetite I am crazy horny from hrt My bones changed from hrt, give it time!! 2 more years hrt YOU WILL PASS trust me oh my god sex is amazing after srs, finally I am a woman!! my vagina just looks and feels like the real deal! I got vrs now I sound like any woman, so easy!!
why is it so hard to be honest about transitioning. It takes so much more than just taking hrt pills. No you will most likely never pass if hrt is the only thing you do. It is for 99% not enough and it is not a crazy drug. It doesn't matter how much you minmax drpower Strat your hrt cycles, this isn't a wonder pill that is is gonna turn you into a woman in a few years
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2024.05.16 08:19 ToothCapital5284 Lost brands for 🍉
| trying the best she can 🥺 lost management and brand deals 😞 had to live with her mom longer 😭 who remembers when she said she had to fire her management company? 🙋🏻♀️ or when she blamed her lost brand deals on being trans and fat? 🙋🏼♀️ or when she admitted brands don’t like her because she’s messy? 🙋🏽♀️ she is such a liarrrrrr, she never ever posted about Palestine as proven by the comments she’d make to people asking her to. And she only posts about it now because she is literally using a g3 n0 c1 d3 to get views 🤢 submitted by ToothCapital5284 to Joolieannie [link] [comments] |
2024.05.16 06:03 ByMyDecree Reviewing and Ranking Every Battle: Bruce Banner vs. Bruce Jenner
Tier List:
https://imgur.com/a/8uZCpGy Oh boy, is this one gonna be a can of worms. Let's dive in headfirst!
"I'll school you in this battle of the baddest Bruce, with your He-Man haircut and your Daisy Dukes." It's an unremarkable line, but the rhythm here is pretty kickass, and I
love the choregraphy of Jenner doing stretches in time with the beat, it's a really satisfying visual. "I hear you're good at running, you're just like the Flash. Especially in the 100-meter ditch-your-wife dash." Decent attack. They never fail to use someone getting divorced as material for a diss, do they? Banner looming over his beakers and microscope is a nice visual, and "You turned one gold medal to a lifetime of green; the most overrated athlete anyone's ever seen" is a competent enough attack. "You need to carry fatherhood across that finish line; kept up with the Kardashians but left some kids behind" is, again, a decent enough diss. A lot of material about Jenner's family here; I guess that's to be expected. There's still one or two much more obvious lines of attack to make, but I suppose Banner is just saving his best stuff for the end, right? He certainly wasn't saving it for the end of
this verse, in which he just references the fact that he transforms when he gets pissed off without fashioning it into much of an attack or boast. The use of strings in the music here is a really nice touch, although I'd say the green screen effect with Bruce standing in front of those neurons or whatever ain't looking so hot.
Actually, the green screen effects for this battle broadly aren't the best. That stadium Jenner's standing in is looking pretty low-res. "I think you're in your element when you're behaving badly; honestly you're kind of boron when you're happy." It's a corny pun, but the sentiment is true enough. "I'll lap and pass your ass ten different ways. Decathlon athlete blast through you like some gamma rays." This is filler; it's fine, rhythm sounds pretty good, but it's just taking up space. "The truth is there's no truce between the Bruces, you're a drifter being useless, I'm a winner, no excuses!" That's a
lot of playing on the same rhyme in a short period of time, and I dig that: truth/truce/Bruces/useless/excuses, hell yeah. I guess some of those aren't proper rhymes so much as, what's the word... assonance, maybe? It's good writing, is the point. The visuals panning in and out of this home gym is a nice touch too, and a nice parallel to Banner's sequence with his lab. "Beatiful women all up on my jock, I got a home gym, check me on the cereal box, Doc!" The rhythm Jenner's spitting here rules, this beat is low-key one of the better ones they've done. It's also a nice boast, and that Wheaties visual is pretty great. "You big green freak, don't try to flex; if it wasn't for your cousin, you'd never have sex!" Okay, this line goes super hard and I think it's one of the most underrated ones in ERB history. AND it's got one of the funniest visuals in the way Jenner pops in on that roller shouting "OHH!" while Banner suffers. That bit lives rent-free in my head. "You're so strong when you get mad, too bad you can't go back to protect your mom from your dad!" Holy fucking SHIT, this goes hard! The flow here kicks all kinds of ass, and we've got a 3x rhyme combo going on with mad/bad/dad; I LOVE odd numbers of rhymes! It's also just an extremely savage low blow. Another line that doesn't get enough credit. Jenner is kicking Banner's ass so far.
One questionable and inadvisable transformation sequence later, The Hulk comes in to spit a few bars. But only a few. "That painted face don't give you class; just one more thing Bruce do for cash!" Interesting argument. "Best thing you make? Kylie ass! She eighteen? Hulk SMASH!!" I do think this is a pretty funny way to reduce Jenner's legacy to Kardashian bullshit, and the Hulk SMASH joke always gets a strong reaction out of people.
Fully transitioned Caitlin Jenner comes in with "That's my teenage daughter, man, I have to forbid this; I'll put a javelin through your jolly green discus." Decent lines. Good way for Caitlin Jenner to brag about her athletic achievements while also throwing a Jolly Green Giant jab in. "Kylie not the kinda girl I'm gonna let you smash on; you'll get the medal without the decathlon!" I like the medeal/metal wordplay here, although Caitlin Jenner dual-wielding pistols and firing them at the Hulk feels extremely out of left field.
"Hulk is Hulk! No identify as man! Me thinks Cait might understand!" Pretty funny line, and Caitlin's reaction is also amusing. "No gender issue; this Jenner issue! Just you being you is enough to diss you!" So that's it, then? They're really not going to bring that one thing up, eh? I feel like that closing line would land a lot better if they did.
"Look I understand that you hate yourself; but you don't need to blame yourself." Oh, huh. That's different. Let's see where this therapy session goes. "You're a tiger, stop trying to tame yourself; you gotta be big enough to contain yourself." Well... I like that she's mixing things up by rhyming with the penultimate word instead of the last word, that's always something. They're clearly going for an angle of Caitlin relating to Bruce and trying to teach him to come to terms with his identity, which is kind of cute, I guess. "Be green, it ain't none of my business!" That line's pretty funny, as is the tea-sipping visual. "But if you think you're looking good in those torn-ass clothes; you're lying, which means you need a new wardrobe!" That's a reference to The Chronicles of Narnia: The Lion, The Witch, and the Wardrobe, which has absolutely nothing to do with this matchup. Feels out of place because of it. And it's not a very strong diss besides, feels like padding. Doubly strange to end her verse on it. "The visions of those shorts kinda scarred me; what'd you just rage at a Barney themed party?" Oh, there's more? Alright. This burn is
really lame. Barney jokes? Come aaaaaaaahhhhhn, what are we doing here? That line should have definitely been left on the cutting room floor. "That's probably not something you seen as a child; not one day did you see your daddy smile!" Okay. She already established that Hulk's father was abusive in her first verse, and while it was a powerful blow there, here it feels much more toothless. "Hulk not strong enough to deal with denial! Laying you down easy; that's kitchen tile!" The first line is pretty amusing with how Caitlin imitates The Hulk's speech, but that second line... why? Pretty weaksauce way to finish her performance off, but whatever. Also not a fan of these visuals with the diamonds, feels like they wanted to add some visual flair but couldn't think of a good way to do it so they settled on Caitlin popping out of diamonds which is just odd. "Examine this under your microscope; you've got no neck, but you still fucking choked!" Oh. This verse is still going? Okay. Well, it's a good line. "After battling me, you're gonna always be pissed! So the Hulk will stay forever, neither Bruce will exist!" You know, that's actually a pretty strong closer, but I can't help but feel like it's undercut by just how long that verse was dragging on.
Okay, so. I feel it should be pointed out that there's a lot of people who were always going to hate this battle for making the decision not to attack Caitlin for being trans. Furthermore, the overwhelming sentiment has been that Banner won this; it bears keeping in mind that there's a lot of transphobes out there who were going to say the Hulk won no matter
what happened simply because Caitlin is trans. So to that end, I think that a fair amount of the hate this battle gets, and the hate that Caitlin's performance gets, is bullshit. But there are still some big criticisms that need to be made.
So let's be honest: they threw the match for Caitlin. Or at least
attempted to. You might still think the Hulk managed to win, but with that insanely long final verse it's pretty clear they tried to make Caitlin the 'canon' winner, as with Thomas Jefferson vs. Frederick Douglass. They did this presumably because it was pride month, and they wanted to say Trans Rights with a trans rapper that gets a positive portrayal. I can get behind that sentiment, but the execution is questionable to say the least.
Like... I'm not trans, but there's some shitty stuff going on here that's easy to see. For one, the cardinal rule that everybody knows is that you're not supposed to misgendedeadname a trans person, and the title of this battle is Bruce Banner vs. Bruce Jenner. So from the get-go, before the video even starts playing, we're getting some mixed signals here. Are we to take from this that they made the tactical decision to go ahead and deadname Caitlin for the sake of the matchup making intuitive sense(what with it obviously being a play on their similar names), and then try and do a hard pivot and make Caitlin win the battle to avoid criticism for that decision? Feels like maybe they could have just not gone with this matchup instead. The whole transformation element also seems dubious, but I could see someone reasonably landing either way on whether that's actually an issue or just silly fun, so I won't go into that.
Another issue to consider: Caitlin Jenner kind of sucks. Most people do not like her. Most
TRANS people don't even like her. For one, despite the fact that she's trans, she is a Republican who has made anti-gay marriage comments in the past. The bizarre shittiness of a trans person being like that is a pretty ripe source of material for disses, yet this battle does not bring it up at all. And more notably than
that, Caitlin Jenner was famously involved with a manslaughter case, where she was accused of getting someone killed due to negligent driving. It was ultimately determined that there wasn't enough evidence for manslaughter and so she wasn't found guilty(though it's widely believed that this decision was bullshit and she did commit manslaughter), but it's an extremely well-known and controversial factoid and it's insane they didn't have Banner bring up as a diss. If you're going to have a rapper make the case of "Just you being you is enough to diss you", seems like being a trans Republican and quite possibly committing vehicular manslaughter are the two strongest and most obvious points to go with. And yet... nothing. If your goal to make a battle that gives trans people positive representation, then Caitlin Jenner is a
pretty poor choice. If you don't want your trans rapper to look like a bad person, then maybe instead of ignoring either elephant in the room, you could just go with some other trans rapper in some other matchup. I get that there aren't a lot of choices for a trans rep with name recognition or ample material to work with, but... the Wachowski sisters are right there. And they've done more to warrant getting in an ERB than Caitlin Jenner anyhow.
Another thing is... why is it a moral imperative that Caitlin win this battle? Sure she's trans, and it's cool to want to give trans people positive representation, but you didn't need to give her an absurdly long verse at the end to do that. You could just give her good writing, refrain from shitting on her just for being trans, and sure, let her have the final word. Then, yes, show the pride flag at the end to say Trans Rights. That's all you had to do. With something like Jefferson v. Douglass the scale-tipping made sense, because it was a slave-owner vs. a slave. Yeah, it's kind of hard for the slave-owner to win that match, and it makes sense to use it as a vehicle to take a firm stand against slavery. But it's not like
this battle is Trans Person vs. Transphobe; Bruce Banner isn't some horrible person that must be morally condemned(there's a much stronger case for Caitlin herself), so... why have it play out like this? I think that ironically, by trying to hand the match to Caitlin they wound up getting more hate thrown towards the performance and more people voting against her in polls than there otherwise would have been if they'd just cut out all that excessive padding and given her a solid closing verse. As-is the verse isn't good, the overall quality is dragged down by just how much fluff there is.
In the end, my read on the situation is this: for whatever reason, they really liked the idea of this matchup and wanted to go through with it. They knew that going through with it would necessitate making it Bruce Banner vs. Bruce Jenner at the start, so they bit the bullet on the deadnaming and the conceit for the matchup and did everything they could to mitigate the potential backlash for that, going as soft on Caitlin as possible and giving her a verse that was ridiculously lengthy. People always say "but it's the Hulk, it makes sense he wouldn't say much!" and sure, I can buy that as an excuse as to why Caitlin's verse would be longER than his, but that still doesn't account for why it's as insanely long as it is. In any case... this paragraph is just speculation, I can't know their actual motivations, but I think this is likely what happened.
Anyway... despite all, this battle gets way too much hate. I think Jenner's first verse is really good, and the Hulk is also quite solid for as few lines as he gets. Bruce Banner is a little mediocre and Caitlin's last verse ends up just being a pain in the ass to sit through(could've been good if they cut all the fat and left in the handful of good lines) that's best skipped past on repeat listens. But still... there's some stuff here that is thoroughly enjoyable. I don't think this battle quite manages to be
good, but it's got enough going for it that I think it manages to avoid being outright bad. I'm putting this in the top of C tier, because I genuinely think it's more enjoyable than all of the battles that are below it.
It's understandable to say that The Hulk beat Jenner's second verse, but I think her first verse was pretty fire and the highlight of the battle. I say she edges out a win, but a case could be made either way.
Let me end things off by saying this: I once watched this battle with an extremely transphobic relative, and he was pissed off by that "no gender issue, this Jenner issue" line. So even if this battle was a regrettable mistake, at least they did
something right.
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